CN106214789A - Herb mixture for the treatment of suckling piglet yellow scours and preparation method thereof - Google Patents
Herb mixture for the treatment of suckling piglet yellow scours and preparation method thereof Download PDFInfo
- Publication number
- CN106214789A CN106214789A CN201610645823.9A CN201610645823A CN106214789A CN 106214789 A CN106214789 A CN 106214789A CN 201610645823 A CN201610645823 A CN 201610645823A CN 106214789 A CN106214789 A CN 106214789A
- Authority
- CN
- China
- Prior art keywords
- parts
- herb mixture
- herba
- suckling piglet
- piglet yellow
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/33—Cactaceae (Cactus family), e.g. pricklypear or Cereus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/739—Sanguisorba (burnet)
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of herb mixture treating suckling piglet yellow scours and preparation method thereof, the raw material of this herb mixture includes the composition of following parts by weight: Herba Portulacae 20～50 parts, Herba Erodii 10～30 parts, Radix Sanguisorbae 10～30 parts, Herba Acalyphae 10～20 parts, Radix et Caulis Opuntiae Dillenii 5～20 parts.The herb mixture of the treatment suckling piglet yellow scours of the present invention through scientific compatibility, has significantly effect for suckling piglet yellow scours, can effectively blocking condition, raising combined therapy effect.
Description
Technical field
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of herb mixture treating suckling piglet yellow scours and preparation side thereof
Method.
Background technology
Due to the unreasonable use of medicine on veterinary clinic, cause animal derived pathogen drug resistance phenomenon abnormal serious, anti-
The best increase with medical expense of bacterium curative effect of medication, sometimes due to treatment the most also causes complication, makes therapeutic effect the best
And cause the continuous Spreading and diffusion of pathogen, cause serious economic loss.Additionally, fastbacteria animal, environment and the mankind it
Between transmit widely and spread one of factor being likely to become serious harm human health[1]。
Escherichia coli are the normal floras of humans and animals intestinal, are also medical science and the modal conditioned pathogen of veterinary clinic
One of, it is possible to the escherichia coli caused a disease specifically include that enterotoxigenic E．Coli (enterotoxigenic E.coli, ETEC),
Escherichia coli (enteropathogenicE.coli, EPEC), enteroinvasive E．Coli (enteroinvasive
E.coli, EIEC), Enterohemorrhagic E.coli (enterohemorrhagic E.coli, EHEC), adhesiveness escherichia coli
(enteroadherent E.coli, EAEC), wherein ETEC is main Escherichia coli.These pathogenic infections
Animal can cause yellow scour of piglet, Hakuri, bowel oedema disease and avian colibacillosis etc., becomes the commonly encountered diseases of puzzlement aquaculture development
One of.For yellow and white dysentery of piglet, the most all having a generation, U.S.'s yellow and white dysentery of piglet obtains sickness rate and is about 16.5% according to statistics,
Mortality rate is up to 15.5%；The sickness rate of Holland's yellow and white dysentery of piglet is about 16.6%, and mortality rate is 11.5 ~ 14.2%[4].China East China
West Large-Scaled Swine Farms, yellow and white dysentery of piglet average attack rate is about 29.0 ± 3.0%, and average mortality reaches 20.4 ±
1.9%.Jiang Zhongqi etc. be isolatable from 10 large-scale pig farms in Zhejiang Province 60 pathogen strain escherichia coli as material, it is right to have carried out
The Monitoring of drug resistance of 21 kinds of antibacterials conventional on veterinary clinic, result show 60 pathogen strain escherichia coli have 57 kinds resistance to
Be there is universal drug resistance by medicine spectral pattern in antibacterials, and the drug resistance of the coli strain on different scales pig farm
There is some difference, and the florfenicol resistant rate that the application time is not grown clinically has reached 60.9%.
The multiple 7 age in days suckling pigs of being born in of yellow scour of piglet, the sick pig mainly row's of showing as yellow or yellow-white watery stools, extremely
Rate of dying up to more than 80%, even 100%.At present conventional medicine mainly has: aminoglycosides, Tetracyclines, chloromycetin,
Part of polypeptide class antibiotic and part sulfonamides and nitrofurans, but owing to Drug Resistance of E. coli constantly strengthens, cause
The therapeutic effect of antibiotic is the best (even to be needed to carry out in advance bacteria drug sensitivity test, or increases using dosage, or multiple
Drug combination and rotation application), make the state of an illness to be controlled effectively, bring harm greatly to Swine Production, because of
The preventing and treating of this primary disease also becomes one of emphasis of piglet diseases control, and various countries are devoted to the effective antibacterials of new type of safe in succession
And the exploitation of succedaneum.
In view of yellow scour of piglet gives the present situation that industrial belt of raising pigs carrys out bigger harm, bacterial drug resistance constantly strengthens relative with treatment
Difficulty and therefore bring the present situation of grave danger to human health, research and development safely and effectively, are not likely to produce the new of drug resistance
Type medicine seems more and more important.
Chinese herbal medicine has nothing/little toxic and side effects, nothing/few hazard residue, nothing/little stress, is not likely to produce drug resistance, no
Pollute the plurality of advantages such as environment, medical science and veterinary clinic are widely used.The harm brought due to antibiotic is got over
Coming the most serious, people start attention to be increasingly turned to Chinese herbal medicine and natural product, it is desirable to be able to find and safely and effectively prevent and treat
The medicine of Animal diseases.Obtained by a kind of herb mixture treating suckling piglet yellow scours of the present invention is studied through clinical practice for many years
It is specifically designed to the Chinese medicine formula for the treatment of yellow scour of piglet.
Summary of the invention
A kind of herb mixture treating suckling piglet yellow scours of the present invention, this mixture is with Herba Portulacae, Herba Erodii, Radix Sanguisorbae, Herba Acalyphae
Dish, Radix et Caulis Opuntiae Dillenii five tastes Chinese herbal medicine, through soak by water twice, collecting decoction, filter, the sepia that filtrate is cooled, concentrating under reduced pressure is made
Liquid preparation.
A kind of herb mixture treating suckling piglet yellow scours of the present invention, it is characterised in that it is by following parts by weight
Raw material forms: Herba Portulacae 20～50 parts, Herba Erodii 10～30 parts, Radix Sanguisorbae 10～30 parts, Herba Acalyphae 10～20 parts, Radix et Caulis Opuntiae Dillenii 5～
20 parts.
Inventive formulation is the most more preferably: Herba Portulacae 350g, Herba Erodii 200g, Radix Sanguisorbae 200g, Herba Acalyphae
150g, Radix et Caulis Opuntiae Dillenii 100g, extracting in water twice, it is evaporated to 1000ml, i.e. every 1ml 1g Han crude drug in whole.
The concrete preparation method of herb mixture that above-mentioned a kind of of the present invention treats suckling piglet yellow scours is as follows: washed by the Chinese medicine of formula ratio
Only, adding 10 times amount water soaking 2 hours, decoct 2 times, 2 hours for the first time, 1 hour for the second time, collecting decoction, filtration, filtrate concentrated
To about 560ml, add 0.5% sodium benzoate, stir evenly, stand 12～24 hours, filter, add the cold water newly boiled and make into
1000ml, subpackage, to obtain final product.
The herb mixture that the present invention is above-mentioned, it is also possible to include following pharmacopedics can adjuvant: as correctives, preservative,
Carrier etc..
For observing its therapeutic effect to yellow scour of piglet, We conducted this product and artificial challenge escherichia coli piglet is controlled
Treat test.
" DLY " tri-crossbreeding 140 of random choose 2～3 age in days, is randomly divided into 5 groups, and artificial vaccination is pathogenic
Escherichia coli O149 K88(except 10 piglets of normal healthy controls group), implement treatment with medicine after 20h.Test high, medium and low dosage group
Each 30 piglets, gavage herb mixture, 30 piglets of drug control group by the dosage of every piglet 3,1.5,0.8 ml respectively, use
Apramycin sulfate soluble powder is soluble in water to be gavaged, and dosage is every kg body weight 8mg.Infect 10 piglets of matched group, not medication.
Each group is administered 2 times equal every day, is used in conjunction 3 days, adds up curative effect after drug withdrawal 3d.Result shows, the dosage group high, middle of herb mixture and
The cure rate of drug control group is more than 90.0%, and the total effective rate of dysentery relieving mixture dosage group high, middle is 96.7%, higher than medicine
Thing matched group, but difference is not notable (P ＞ 0.05).Result of the test shows that yellow scour of piglet is had relatively by the dysentery relieving mixture of dosage high, middle
Good curative effect.
A kind of herb mixture treating suckling piglet yellow scours of the present invention, through scientific compatibility, has substantially for suckling piglet yellow scours
Effect, can effective blocking condition, improve combined therapy effect.Using method is every 1.5ml, every day 2 times, is used in conjunction 3～5
My god.
Detailed description of the invention
Embodiment 1:
A kind of herb mixture treating suckling piglet yellow scours, it is made up of the raw material of following parts by weight: Herba Portulacae 300g, Herba Erodii
200g, Radix Sanguisorbae 200g, Herba Acalyphae 150g, Radix et Caulis Opuntiae Dillenii 150g, extracting in water twice, it is evaporated to 1000ml, i.e. every 1ml is containing former
Crude drug 1g.
Embodiment 2:
A kind of herb mixture treating suckling piglet yellow scours, it is made up of the raw material of following parts by weight: Herba Portulacae 300g, Herba Erodii
200g, Radix Sanguisorbae 200g, Herba Acalyphae 100g, Radix et Caulis Opuntiae Dillenii 200g, extracting in water twice, it is evaporated to 1000ml, i.e. every 1ml is containing former
Crude drug 1g.
Being described in detail the specific embodiment of the present invention above, but it is intended only as example, the present invention does not limit
It is formed on particular embodiments described above.To those skilled in the art, any equivalent modifications that the present invention is carried out and
Substitute the most all among scope of the invention.Therefore, in the impartial conversion made without departing from the spirit and scope of the invention and
Amendment, all should contain within the scope of the invention.
Claims (2)
1. treat a herb mixture for suckling piglet yellow scours, be characterised by: its raw material includes bitterroot, Herba Erodii, Radix Sanguisorbae, Herba Acalyphae
Dish, Radix et Caulis Opuntiae Dillenii.
A kind of herb mixture treating suckling piglet yellow scours the most according to claim 1, is characterised by: its raw material includes following
The composition of parts by weight: Herba Portulacae 20～50 parts, Herba Erodii 10～30 parts, Radix Sanguisorbae 10～30 parts, Herba Acalyphae 10～20 parts, celestial being
Slap 5～20 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610645823.9A CN106214789A (en) | 2016-08-09 | 2016-08-09 | Herb mixture for the treatment of suckling piglet yellow scours and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610645823.9A CN106214789A (en) | 2016-08-09 | 2016-08-09 | Herb mixture for the treatment of suckling piglet yellow scours and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106214789A true CN106214789A (en) | 2016-12-14 |
Family
ID=57548699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610645823.9A Pending CN106214789A (en) | 2016-08-09 | 2016-08-09 | Herb mixture for the treatment of suckling piglet yellow scours and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106214789A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109349425A (en) * | 2018-10-27 | 2019-02-19 | 江苏波杜农牧股份有限公司 | A kind of Chinese herbal feed additive and preparation method thereof |
| CN109512934A (en) * | 2017-09-20 | 2019-03-26 | 扬中牧乐药业有限公司 | A kind of oral solution and preparation method thereof for treating swine enteritis |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101385803A (en) * | 2008-10-24 | 2009-03-18 | 扬中牧乐药业有限公司 | Compound Chinese herbal medicine extract liquid for preventing and treating livestock and birds diarrhea and preparation thereof |
| CN103191175A (en) * | 2013-04-18 | 2013-07-10 | 重庆市中药研究院 | Diarrhoea-stopping traditional Chinese medicine composition, capsule and application thereof |
-
2016
- 2016-08-09 CN CN201610645823.9A patent/CN106214789A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101385803A (en) * | 2008-10-24 | 2009-03-18 | 扬中牧乐药业有限公司 | Compound Chinese herbal medicine extract liquid for preventing and treating livestock and birds diarrhea and preparation thereof |
| CN103191175A (en) * | 2013-04-18 | 2013-07-10 | 重庆市中药研究院 | Diarrhoea-stopping traditional Chinese medicine composition, capsule and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 颜邦斌: "马齿苋治猪病妙方", 《农村百事通》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109512934A (en) * | 2017-09-20 | 2019-03-26 | 扬中牧乐药业有限公司 | A kind of oral solution and preparation method thereof for treating swine enteritis |
| CN109349425A (en) * | 2018-10-27 | 2019-02-19 | 江苏波杜农牧股份有限公司 | A kind of Chinese herbal feed additive and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104522358A (en) | Chinese herbal medicine microbial ecological agent for improving weight of weaned pig and preparation method of Chinese herbal medicine microbial ecological agent | |
| CN103893272A (en) | Pharmaceutical composition for treating livestock diarrhea and preparation method thereof | |
| CN102772478A (en) | Chinese medicinal granule for enhancing immunity of livestock and poultry | |
| CN103355500A (en) | Rabbit feed additive | |
| CN103006916A (en) | Pure traditional Chinese medicine recipe for curing various animal diarrhoeal diseases and preparation method of pure traditional Chinese medicine recipe | |
| CN101209307A (en) | Chinese medicinal oral liquid with heat-clearing and detoxication, dampness-eliminating and dysentery-stopping efficacy | |
| CN105166544A (en) | Pig mixed feed and preparation method thereof | |
| CN103877229B (en) | A kind of compound Chinese medicine extract and application thereof preventing and treating an avian colibacillosis | |
| CN102671011B (en) | Traditional Chinese medicine compound powder for preventing and treating yellow and white scour of piglets and preparation method thereof | |
| CN101396462A (en) | Traditional Chinese medicine oral liquid for treating livestock and poultry digestive canal disease | |
| CN106214789A (en) | Herb mixture for the treatment of suckling piglet yellow scours and preparation method thereof | |
| CN109528895A (en) | It is a kind of for treating the Chinese medicine composition and preparation method of animal diarrhea | |
| CN103861007B (en) | A kind of Chinese herbal compound preparation for the treatment of chicken diarrhea | |
| CN107812166A (en) | A kind of feed addictive for preventing fish acute gastroenteritis and preparation method thereof | |
| CN109432287B (en) | Traditional Chinese medicine oral liquid for preventing and treating excessive heat syndrome of poultry qi system and preparation method thereof | |
| CN102961405A (en) | Secretio bufonis injection for treating yellow and white scour of newborn piglets, and preparation method of injection | |
| CN105707898A (en) | Toxin removing and bowel relaxing probiotic composition and preparation method and application thereof | |
| CN105582413A (en) | Pharmaceutical composition for preventing and treating piglet diarrhea and preparation method of pharmaceutical composition | |
| CN105748873A (en) | Veterinary traditional Chinese medicine particle for treating livestock and poultry respiratory tract infection | |
| CN104606627B (en) | A kind of pharmaceutical composition for treating grice diarrhoea and preparation method thereof | |
| AU2021105905A4 (en) | A Pharmaceutical Composition for Treating Diarrhea Of Piglet And Its Preparation Method | |
| CN101375931A (en) | Chinese medicine oral liquid with heat-clearing and dampness-draining functions as well as application thereof for livestock and poultry | |
| CN114099573B (en) | Traditional Chinese medicine composition for improving egg laying performance of laying hens as well as preparation method and application of traditional Chinese medicine composition | |
| CN103007270B (en) | Injection injected into acupoint Houhai to treat piglet diarrhea | |
| CN101375934A (en) | Chinese medicine oral liquid with heat-clearing and detoxicating, antibiotic and anti-dysentery functions as well as application thereof for livestock and poultry |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20161214 |