CN106214633A - A kind of preparation method of ecosystem Ganoderma oral liquid - Google Patents
A kind of preparation method of ecosystem Ganoderma oral liquid Download PDFInfo
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- CN106214633A CN106214633A CN201610777335.3A CN201610777335A CN106214633A CN 106214633 A CN106214633 A CN 106214633A CN 201610777335 A CN201610777335 A CN 201610777335A CN 106214633 A CN106214633 A CN 106214633A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention discloses the preparation method of a kind of ecosystem Ganoderma oral liquid, cultivation including (1) Ganoderma, (2) enrichment of glossy ganoderma nutrient solution, (3) humidification of Ganoderma sporophore, (4) collection of glossy ganoderma nutrient solution, (5) concentration of nutritional solution, the mixing of (6) nutritional solution, the fill of (7) nutritional solution and sterilization steps.The ecosystem Ganoderma oral liquid that preparation method of the present invention prepares, containing abundant nutritional labeling and healthy ingredient, has significant cough-relieving, reduces phlegm and improve the effect of immune function of human body.The active component obtaining Ganoderma of the inventive method maximizing, remains its nutritional labeling to greatest extent；The effective ingredient in the Ganoderma oral liquid of present invention acquisition is used to be water miscible, it is easy to absorption of human body；Do not introduce other chemical reagent during the whole extraction of the present invention, there is not chemical contamination；The Ganoderma oral liquid obtained does not adds other functional extract, there is not the phenomenon that many kinds of substance mutually suppresses, causes effect to reduce.
Description
Technical field
The present invention relates to the preparation method of a kind of oral liquid, the preparation method of a kind of ecosystem Ganoderma oral liquid,
Belong to health product processing technique field.
Background technology
Ganoderma be a kind of be On Polyporaceae also known as Lin Zhongling, fine jade precious (formal name used at school: Ganoderma Lucidum Karst)
The sporophore of Ganoderma, has effect of invigorating QI and tranquilization, relieving cough and asthma, life lengthening.For dizziness sleeplessness, shortness of breath and palpitation, nerve
Weak, asthenia cough with asthma.
Application 201310625029.4 discloses a kind of by Ganoderma 290～310 mass parts, Agaricus blazei Murrill 290～310 mass
Part, Herba Epimedii 190～210 mass parts；Also include following adjuvant: stevioside 0.4～0.6 mass parts, potassium sorbate 0.4～
Ganoderma oral liquid prepared by 0.6 mass parts, purified water；02151036.9 disclose a kind of Ganoderma, the Cortex Eucommiae, the Radix Astragali, Spica Prunellae,
Dragon, Radix Polygoni Multiflori Preparata, Radix Salviae Miltiorrhizae, Semen Cuscutae are Ganoderma oral liquid prepared by raw material；Application 93103116.8 discloses a kind of by 94%
The wild Ganoderma biofermentation concentrated stock solution of 96% and adjuvant (ethyl lactate, citric acid, Mel, really grass juice factor, the Osmanthus tragranscv.Aurantiacu of 4%-6%
Water, fiber crops Rhizoma Zingiberis Recens liquid etc.) Ganoderma oral liquid prepared.Although prior art discloses product or the preparation method of Ganoderma oral liquid, but
Due to the restriction of extractive technique, existing Ganoderma oral liquid effective ingredient therein can not extract completely；And most Ganoderma mouth
Take liquid product to increase effect of product, the joining of product adds other Chinese herbal medicine material；Although can be necessarily
Realize the complementation of effect in degree, but owing to material composition is more, occur between raw material unavoidably or raw material is in preparation process
In intermediate product between, there is the phenomenon of mutually suppression between functional extract, ultimately result in the reduction of product efficacy.
Summary of the invention
It is an object of the invention to provide the preparation method of a kind of ecosystem Ganoderma oral liquid, the method with Ganoderma as raw material,
By taking measures to be enriched with and obtain the nutritional solution of optimum state at the cultivation of Ganoderma, and when collecting nutritional solution, in conjunction with
Freezing, pulverizing, hot water extraction etc. process, the maximized active component obtaining Ganoderma, remain the nutrition of raw material to greatest extent
Composition；The effective ingredient in the Ganoderma oral liquid of present invention acquisition is used to be water miscible, it is easy to absorption of human body；System of the present invention
Do not introduce other chemical reagent during the whole extraction of Preparation Method, there is not chemical contamination；The Ganoderma oral liquid of the present invention does not has
There is other functional extract of interpolation, there is not the phenomenon that many kinds of substance mutually suppresses, causes effect to reduce.
Technical scheme is as follows: the preparation method of a kind of Ganoderma oral liquid, comprises the steps:
(1) cultivation of Ganoderma: by quality proportioning, with Maninot esculenta crantz. cane 45 ~ 55%, cotton seed hulls 30 ~ 38%, Testa Tritici 2 ~ 8%, Semen Maydis powder 5 ~
15%, Calx 1 ~ 4% is raw material, is fabricated to bacterium bag, and bacterium bag, through 100 DEG C of sterilizing 10h, is cooled to room temperature, inoculation, postvaccinal bacterium bag
Being placed under dark room conditions and carry out mycelial growth, control ambient temperature and be 25-28 DEG C, humidity is 50-60%；After growing 30-40 days
Entering the sporophore growth phase, control ambient temperature and be 27-30 DEG C, humidity is 85%-95%；
(2) enrichment of glossy ganoderma nutrient solution: when sporophore enters Later growth, and cap edge thinning, white portion starts progressively to disappear
Missing the season, start to increase ambient humidity and be 24-26 DEG C to 95-100%, temperature, endobacillary moisture is gradually increased, and keeps increasing
Wet 2-5 days, Ganoderma water content, at 30-40%, started to start to gather before Ganoderma is dusted to fresh sesame；
(3) humidification of Ganoderma sporophore: the Ganoderma after plucking is cleaned, and the Ganoderma after cleaning is placed in vacuum tank humidification, it is thus achieved that
Ganoderma after damping, its water content is 40-70%；
(4) collection of glossy ganoderma nutrient solution: by the Ganoderma after damping, freezing 1-3 days at being placed in-20 DEG C；Ganoderma after freezing is placed in
Pulverizer is pulverized 1-2min, then carries out 10-40 mesh coarse filtration, collect filtrate, obtain filtrate 1；Filtrate 1 is placed in tubular type from
Scheming is centrifuged, obtains filtrate 2 and residual residue；Residual residue clean water is soaked 10min-20min, soaks after terminating, enter
Row heating steaming and decocting, heats while stirring, heating-up temperature 70-90 DEG C, steaming and decocting 1-3h；Then carry out 10-40 mesh coarse filtration, remove filter
Slag, collects filtrate, obtains filtrate 3；Filtrate 3 is placed in tube centrifuge and is centrifuged, and collects clear liquid, obtains filtrate 4；
(5) concentration of nutritional solution: filtrate 4 is placed in vacuum concentrator concentration, and thickening temperature is 55-60 DEG C, vacuum is-
0.08 ~ (-) 0.1Mpa, time 30-120min, being concentrated into concentration of soluble solids is that 2-7%(20 DEG C of refractometer measures), obtain
Filtrate 4 after must concentrating；
(6) mixing of nutritional solution: by the filtrate 4 after filtrate 2 and concentration, mix according to 1:1, obtain glossy ganoderma nutrient solution；
(7) fill of glossy ganoderma nutrient solution and sterilizing: by ganoderma lucidum flow container in the bottle of 10ml, capping preserves, then as
In moist heat sterilizer 121 DEG C, process 30min, after sterilizing terminates, cooling, packaging, obtain ecosystem Ganoderma oral liquid.
Further, the actual conditions that described step (3) is humidified is as follows: the Ganoderma after cleaning and water are according to material water quality
Ratio is placed in vacuum tank for 1:3-6, and the vacuum of vacuum tank-0.08 ~ (-) 0.1Mpa, humidification time 10-20min.
It is furthermore preferred that described material water quality is than for 1:5.
Further, in described step (4), filtrate 1, the centrifugal rotational speed of filtrate 3 are 15000-18000r/min.
Further, in described step (4), the ratio of material water quality when residual residue is soaked is for 1:5-1:15.
Further, described bacterium packs that to make the quality proportioning of raw material as follows: Maninot esculenta crantz. cane 50%, cotton seed hulls 33%, Testa Tritici 5%,
Semen Maydis powder 10%, Calx 2%.
Described bacterium bag is preferably 15 × 50cm size；Also can be fabricated to satisfactory bacterium bag according to actual production demand.
The ecosystem Ganoderma oral liquid that preparation method of the present invention prepares, containing abundant nutritional labeling and healthy ingredient, tool
There is significant cough-relieving, reduce phlegm and improve the effect of immune function of human body.
The present invention also resides in relative to the beneficial effect of prior art:
(1) can be increased the water content of Ganoderma sporophore by the enriching step of nutritional solution, this part increases water content, on the one hand profit
In the harvesting of Ganoderma, on the other hand, promotion moisture is in Ganoderma sporophore cell, intercellular diffusion, so that activity becomes
The increase divided；
(2) humidification step of Ganoderma sporophore can increase the water content of Ganoderma sporophore further by the effect of external force, pass through
The principle of low concentration infiltration, promotes the cracking of cell；It is beneficial to the freezing of Ganoderma and the broken of Ganoderma simultaneously；
(3), during the collection of glossy ganoderma nutrient solution, first at-20 DEG C, Ganoderma being carried out freezing processing is carrying out the steps such as follow-up pulverizing,
By freezing in advance, the moisture of the Ganoderma after freezing is in crystalline state, when carrying out follow-up pulverizing, at the work of mechanical external force
Under with, so that Ganoderma pulverizing is more thorough, the internal activity of Ganoderma is easier to spilling and release simultaneously；
(4) residual residue obtained after pulverizing, be centrifuged carries out hot water extraction, on the one hand, can obtain spirit by hot water extraction
The water soluble ingredient being easily absorbed by the body in sesame, on the other hand can obtain in Ganoderma and need the most just can extract
Particular functionality composition；First carry out the removable macromolecular particle of coarse filtration after hot water extraction, reduce follow-up employing tubular type when being centrifuged
Macromolecular particle on centrifugal impact, also can make extract and the outward appearance of final products and state more preferably simultaneously；
(5) filtrate 4 after filtrate 2 and concentration being mixed to obtain glossy ganoderma nutrient solution, the nutrition that can retain filtrate 2 to greatest extent becomes
Dividing, and the nutritional labeling of filtrate 4 has certain toleration to temperature, after concentrating, nutritive validity will not lose too much；
(6) effective ingredient in the Ganoderma oral liquid of the present invention is water miscible, it is easy to absorption of human body；Preparation method of the present invention
Do not introduce other chemical reagent during whole extraction, there is not chemical contamination；The Ganoderma oral liquid of the present invention does not add
, there is not the phenomenon that many kinds of substance mutually suppresses, causes effect to reduce in other functional extract.
Detailed description of the invention
Being described in further details the present invention below by embodiment, these embodiments are only used for the present invention is described, and
Do not limit the scope of the invention.
Embodiment 1 uses following steps to prepare ecosystem Ganoderma oral liquid:
(1) cultivation of Ganoderma: by quality proportioning, with Maninot esculenta crantz. cane 50%, cotton seed hulls 33%, Testa Tritici 5%, Semen Maydis powder 10%, Calx 2%
For raw material, being fabricated to the bacterium bag of 15 × 50cm size, bacterium bag, through 100 DEG C of sterilizing 10h, is cooled to room temperature, inoculation, postvaccinal bacterium
Bag is placed under dark room conditions and carries out mycelial growth, controls ambient temperature and is 25-28 DEG C, and humidity is 50-60%；Grow 30-40 days
The rear entrance sporophore growth phase, controlling ambient temperature and be 27-30 DEG C, humidity is 85%-95%；
(2) enrichment of glossy ganoderma nutrient solution: when sporophore enters Later growth, and cap edge thinning, white portion starts progressively to disappear
Miss the season, start to increase ambient humidity and be 24-26 DEG C to 95-100%, temperature, increase endobacillary moisture, keep humidification 2-5
My god, Ganoderma water content, at 30-40%, starts to start to gather before Ganoderma is dusted to fresh sesame；
(3) humidification of Ganoderma sporophore: the Ganoderma after plucking is cleaned, the Ganoderma after cleaning with water according to material water quality ratio is
1:5 is placed in vacuum tank, and the vacuum of vacuum tank-0.08 ~ (-) 0.1Mpa, humidification time 10-20min, it is thus achieved that after damping
Ganoderma, its water content is 40-70%；
(4) collection of glossy ganoderma nutrient solution: by the Ganoderma after damping, freezing 1-3 days at being placed in-20 DEG C；Ganoderma after freezing is placed in
Pulverizer is pulverized 1-2min, then carries out 10-40 mesh coarse filtration, collect filtrate, obtain filtrate 1；Filtrate 1 is placed in tubular type from
Scheming is centrifuged with rotating speed 17000r/min, obtains filtrate 2 and residual residue；By residual residue clean water by material water quality ratio it is
1:10 soaks 15min, soaks after terminating, and carries out heating steaming and decocting, heats while stirring, heating-up temperature 70-90 DEG C, steaming and decocting 2h；So
After carry out 10-40 mesh coarse filtration, remove filtering residue, collect filtrate, obtain filtrate 3；Filtrate 3 is placed in tube centrifuge with rotating speed
17000r/min is centrifuged, and collects clear liquid, obtains filtrate 4；
(5) concentration of nutritional solution: filtrate 4 is placed in vacuum concentrator concentration, and thickening temperature is 55-60 DEG C, vacuum is-
0.08 ~ (-) 0.1Mpa, time 90min, being concentrated into concentration of soluble solids is that 2-7%(20 DEG C of refractometer measures), it is thus achieved that dense
Filtrate 4 after contracting；
(6) mixing of nutritional solution: by the filtrate 4 after filtrate 2 and concentration, mix according to 1:1, obtain glossy ganoderma nutrient solution；
(7) fill of glossy ganoderma nutrient solution and sterilizing: by ganoderma lucidum flow container in the bottle of 10ml, capping preserves, then as
In moist heat sterilizer 121 DEG C, process 30min, after sterilizing terminates, cooling, packaging, obtain ecosystem Ganoderma oral liquid.
Embodiment 2 uses following steps to prepare ecosystem Ganoderma oral liquid:
(1) cultivation of Ganoderma: by quality proportioning, with Maninot esculenta crantz. cane 45%, cotton seed hulls 38%, Testa Tritici 2%, Semen Maydis powder 14%, Calx 1%
For raw material, being fabricated to the bacterium bag of 15 × 50cm size, bacterium bag, through 100 DEG C of sterilizing 10h, is cooled to room temperature, inoculation, postvaccinal bacterium
Bag is placed under dark room conditions and carries out mycelial growth, controls ambient temperature and is 25-28 DEG C, and humidity is 50-60%；Grow 30-40 days
The rear entrance sporophore growth phase, controlling ambient temperature and be 27-30 DEG C, humidity is 85%-95%；
(2) enrichment of glossy ganoderma nutrient solution: when sporophore enters Later growth, and cap edge thinning, white portion starts progressively to disappear
Miss the season, start to increase ambient humidity and be 24-26 DEG C to 95-100%, temperature, increase endobacillary moisture, keep humidification 2-5
My god, Ganoderma water content, at 30-40%, starts to start to gather before Ganoderma is dusted to fresh sesame；
(3) humidification of Ganoderma sporophore: the Ganoderma after plucking is cleaned, the Ganoderma after cleaning with water according to material water quality ratio is
1:3-6 is placed in vacuum tank, and the vacuum of vacuum tank-0.08 ~ (-) 0.1Mpa, humidification time 10-20min, it is thus achieved that after damping
Ganoderma, its water content is 40-70%；
(4) collection of glossy ganoderma nutrient solution: by the Ganoderma after damping, freezing 1-3 days at being placed in-20 DEG C；Ganoderma after freezing is placed in
Pulverizer is pulverized 1-2min, then carries out 10-40 mesh coarse filtration, collect filtrate, obtain filtrate 1；Filtrate 1 is placed in tubular type from
Scheming is centrifuged with rotating speed 15000r/min, obtains filtrate 2 and residual residue；By residual residue clean water by material water quality ratio it is
1:15 soaks 10min, soaks after terminating, and carries out heating steaming and decocting, heats while stirring, heating-up temperature 70-90 DEG C, steaming and decocting 3h；So
After carry out 10-40 mesh coarse filtration, remove filtering residue, collect filtrate, obtain filtrate 3；Filtrate 3 is placed in tube centrifuge with rotating speed
15000r/min is centrifuged, and collects clear liquid, obtains filtrate 4；
(5) concentration of nutritional solution: filtrate 4 is placed in vacuum concentrator concentration, and thickening temperature is 55-60 DEG C, vacuum is-
0.08 ~ (-) 0.1Mpa, time 30min, being concentrated into concentration of soluble solids is that 2-7%(20 DEG C of refractometer measures), it is thus achieved that dense
Filtrate 4 after contracting；
(6) mixing of nutritional solution: by the filtrate 4 after filtrate 2 and concentration, mix according to 1:1, obtain glossy ganoderma nutrient solution；
(7) fill of glossy ganoderma nutrient solution and sterilizing: by ganoderma lucidum flow container in the bottle of 10ml, capping preserves, then as
In moist heat sterilizer 121 DEG C, process 30min, after sterilizing terminates, cooling, packaging, obtain ecosystem Ganoderma oral liquid.
Embodiment 3 uses following steps to prepare ecosystem Ganoderma oral liquid:
(1) cultivation of Ganoderma: by quality proportioning, with Maninot esculenta crantz. cane 55%, cotton seed hulls 30%, Testa Tritici 8%, Semen Maydis powder 5%, Calx 2% be
Raw material, is fabricated to the bacterium bag of 15 × 50cm size, and bacterium bag, through 100 DEG C of sterilizing 10h, is cooled to room temperature, inoculation, postvaccinal bacterium bag
Being placed under dark room conditions and carry out mycelial growth, control ambient temperature and be 25-28 DEG C, humidity is 50-60%；After growing 30-40 days
Entering the sporophore growth phase, control ambient temperature and be 27-30 DEG C, humidity is 85%-95%；
(2) enrichment of glossy ganoderma nutrient solution: list entity enters Later growth, and cap edge thinning, white portion starts progressively to disappear
Miss the season, start to increase ambient humidity and be 24-26 DEG C to 95-100%, temperature, increase endobacillary moisture, keep humidification 2-5
My god, Ganoderma water content, at 30-40%, starts to start to gather before Ganoderma is dusted to fresh sesame；
(3) humidification of Ganoderma sporophore: the Ganoderma after plucking is cleaned, the Ganoderma after cleaning with water according to material water quality ratio is
1:3 is placed in vacuum tank, and the vacuum of vacuum tank-0.08 ~ (-) 0.1Mpa, humidification time 10-20min, it is thus achieved that after damping
Ganoderma, its water content is 40-70%；
(4) collection of glossy ganoderma nutrient solution: by the Ganoderma after damping, freezing 1-3 days at being placed in-20 DEG C；Ganoderma after freezing is placed in
Pulverizer is pulverized 1-2min, then carries out 10-40 mesh coarse filtration, collect filtrate, obtain filtrate 1；Filtrate 1 is placed in tubular type from
Scheming is centrifuged with rotating speed 18000r/min, obtains filtrate 2 and residual residue；By residual residue clean water by material water quality ratio it is
1:5 soaks 20min, soaks after terminating, and carries out heating steaming and decocting, heats while stirring, heating-up temperature 70-90 DEG C, steaming and decocting 1h；Then
Carry out 10-40 mesh coarse filtration, remove filtering residue, collect filtrate, obtain filtrate 3；Filtrate 3 is placed in tube centrifuge with rotating speed
18000r/min is centrifuged, and collects clear liquid, obtains filtrate 4；
(5) concentration of nutritional solution: filtrate 4 is placed in vacuum concentrator concentration, and thickening temperature is 55-60 DEG C, vacuum is-
0.08 ~ (-) 0.1Mpa, time 120min, being concentrated into concentration of soluble solids is that 2-7%(20 DEG C of refractometer measures), it is thus achieved that
Filtrate 4 after concentration；
(6) mixing of nutritional solution: by the filtrate 4 after filtrate 2 and concentration, mix according to 1:1, obtain glossy ganoderma nutrient solution；
(7) fill of glossy ganoderma nutrient solution and sterilizing: by ganoderma lucidum flow container in the bottle of 10ml, capping preserves, then as
In moist heat sterilizer 121 DEG C, process 30min, after sterilizing terminates, cooling, packaging, obtain ecosystem Ganoderma oral liquid.
Claims (6)
1. the preparation method of an ecosystem Ganoderma oral liquid, it is characterised in that: comprise the steps:
(1) cultivation of Ganoderma: by quality proportioning, with Maninot esculenta crantz. cane 45 ~ 55%, cotton seed hulls 30 ~ 38%, Testa Tritici 2 ~ 8%, Semen Maydis powder 5 ~
15%, Calx 1 ~ 4% is raw material, is fabricated to bacterium bag, and bacterium bag, through 100 DEG C of sterilizing 10h, is cooled to room temperature, inoculation, postvaccinal bacterium bag
Being placed under dark room conditions and carry out mycelial growth, control ambient temperature and be 25-28 DEG C, humidity is 50-60%；After growing 30-40 days
Entering the sporophore growth phase, control ambient temperature and be 27-30 DEG C, humidity is 85%-95%；
(2) enrichment of glossy ganoderma nutrient solution: when sporophore enters Later growth, and cap edge thinning, white portion starts progressively to disappear
Missing the season, now thalli growth is slow, starts to increase ambient humidity and is 24-26 DEG C to 95-100%, ambient temperature, increases in thalline
Moisture, keep humidification 2-5 days, Ganoderma water content, at 30-40%, starts to start to gather before Ganoderma is dusted to fresh sesame；
(3) humidification of Ganoderma sporophore: the Ganoderma after plucking is cleaned, and the Ganoderma after cleaning is placed in vacuum tank humidification, it is thus achieved that
Ganoderma after damping, its water content is 40-70%；
(4) collection of glossy ganoderma nutrient solution: by the Ganoderma after damping, freezing 1-3 days at being placed in-20 DEG C；Ganoderma after freezing is placed in
Pulverizer is pulverized 1-2min, then carries out 10-40 mesh coarse filtration, collect filtrate, obtain filtrate 1；Filtrate 1 is placed in tubular type from
Scheming is centrifuged, obtains filtrate 2 and residual residue；Residual residue clean water is soaked 10min-20min, soaks after terminating, enter
Row heating steaming and decocting, heats while stirring, heating-up temperature 70-90 DEG C, steaming and decocting 1-3h；Then carry out 10-40 mesh coarse filtration, remove filter
Slag, collects filtrate, obtains filtrate 3；Filtrate 3 is placed in tube centrifuge and is centrifuged, and collects clear liquid, obtains filtrate 4；
(5) concentration of nutritional solution: filtrate 4 is placed in vacuum concentrator concentration, and thickening temperature is 55-60 DEG C, vacuum is-
0.08 ~ (-) 0.1Mpa, time 30-120min, being concentrated into concentration of soluble solids is that 2-7%(20 DEG C of refractometer measures), obtain
Filtrate 4 after must concentrating；
(6) mixing of nutritional solution: by the filtrate 4 after filtrate 2 and concentration, mix according to 1:1, obtain glossy ganoderma nutrient solution；
(7) fill of glossy ganoderma nutrient solution and sterilizing: by ganoderma lucidum flow container in the bottle of 10ml, capping preserves, then as
In moist heat sterilizer 121 DEG C, process 30min, after sterilizing terminates, cooling, packaging, obtain ecosystem Ganoderma oral liquid.
Preparation method the most according to claim 1, it is characterised in that: the actual conditions that described step (3) is humidified is as follows: will
Ganoderma after cleaning and water are placed in vacuum tank than for 1:3-6 according to material water quality, and the vacuum of vacuum tank-0.08 ~ (-)
0.1Mpa, humidification time 10-20min.
Preparation method the most according to claim 2, it is characterised in that: described material water quality is than for 1:5.
Preparation method the most according to claim 1, it is characterised in that: in described step (4), filtrate 1, filtrate 3 centrifugal
Rotating speed is 15000-18000r/min.
Preparation method the most according to claim 1, it is characterised in that: the material in described step (4), when residual residue is soaked
Water quality is than for 1:5-1:15.
Preparation method the most according to claim 1, it is characterised in that: described bacterium packs that to make the quality proportioning of raw material as follows:
Maninot esculenta crantz. cane 50%, cotton seed hulls 33%, Testa Tritici 5%, Semen Maydis powder 10%, Calx 2%.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106489541A (en) * | 2016-12-20 | 2017-03-15 | 福建农林大学 | A kind of Ganoderma fruiting method |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN85100417A (en) * | 1985-04-01 | 1986-07-09 | 山东省枣庄市薛城真菌实验站 | Greenhouse cultivation of ganoderma lucidum |
| CN1056057A (en) * | 1991-05-26 | 1991-11-13 | 裴留成 | The preparation method of " Linglan " concentrated liquid |
| CN1099239A (en) * | 1994-05-28 | 1995-03-01 | 徐士杰 | Lucid ganoderma syrup and its preparation |
| CN1786033A (en) * | 2005-07-22 | 2006-06-14 | 天津市林业果树研究所 | Preparation process of lucid ganoderma polysaccharide |
| CN102578349A (en) * | 2012-02-07 | 2012-07-18 | 何松庆 | Pressed candies added with fresh glossy ganoderma full-juice powder |
| CN102824377A (en) * | 2012-09-20 | 2012-12-19 | 江南大学 | Method for extracting functional ingredients from lucid ganoderma sporocarp |
| CN102870595A (en) * | 2012-09-13 | 2013-01-16 | 广东省微生物研究所 | Artificial cultivation method capable of realizing highland cultivation of wild ganoderma tsugae murr |
| CN102920749A (en) * | 2012-11-05 | 2013-02-13 | 广西仙草堂制药有限责任公司 | Method for preparing fully-effective ganoderma lucidum health care product |
-
2016
- 2016-08-31 CN CN201610777335.3A patent/CN106214633B/en active Active
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN85100417A (en) * | 1985-04-01 | 1986-07-09 | 山东省枣庄市薛城真菌实验站 | Greenhouse cultivation of ganoderma lucidum |
| CN1056057A (en) * | 1991-05-26 | 1991-11-13 | 裴留成 | The preparation method of " Linglan " concentrated liquid |
| CN1099239A (en) * | 1994-05-28 | 1995-03-01 | 徐士杰 | Lucid ganoderma syrup and its preparation |
| CN1786033A (en) * | 2005-07-22 | 2006-06-14 | 天津市林业果树研究所 | Preparation process of lucid ganoderma polysaccharide |
| CN102578349A (en) * | 2012-02-07 | 2012-07-18 | 何松庆 | Pressed candies added with fresh glossy ganoderma full-juice powder |
| CN102870595A (en) * | 2012-09-13 | 2013-01-16 | 广东省微生物研究所 | Artificial cultivation method capable of realizing highland cultivation of wild ganoderma tsugae murr |
| CN102824377A (en) * | 2012-09-20 | 2012-12-19 | 江南大学 | Method for extracting functional ingredients from lucid ganoderma sporocarp |
| CN102920749A (en) * | 2012-11-05 | 2013-02-13 | 广西仙草堂制药有限责任公司 | Method for preparing fully-effective ganoderma lucidum health care product |
Non-Patent Citations (6)
| Title |
|---|
| 余虹: "灵芝栽培技术", 《四川农业科技》 * |
| 刘钧发，等: "超声和水提法提取灵芝多糖的结构和抗氧化性的比较研究", 《食品工业科技》 * |
| 叶向花，等: "灵芝栽培新技术", 《现代农业科技》 * |
| 牟建楼，等: "灵芝水提物及其抗氧化性研究", 《食品科技》 * |
| 罗光明，等: "《药用植物栽培学》", 31 January 2013, 上海科学技术出版社 * |
| 邢小黑，等: "灵芝保健食品的研制", 《中国食用菌》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106489541A (en) * | 2016-12-20 | 2017-03-15 | 福建农林大学 | A kind of Ganoderma fruiting method |
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