CN106178035A - A kind of Antipollution method of spray bottle - Google Patents
A kind of Antipollution method of spray bottle Download PDFInfo
- Publication number
- CN106178035A CN106178035A CN201610532138.5A CN201610532138A CN106178035A CN 106178035 A CN106178035 A CN 106178035A CN 201610532138 A CN201610532138 A CN 201610532138A CN 106178035 A CN106178035 A CN 106178035A
- Authority
- CN
- China
- Prior art keywords
- quintessence oil
- clathrate
- spray bottle
- cyclodextrin
- bottle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/22—Phase substances, e.g. smokes, aerosols or sprayed or atomised substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/10—Apparatus features
- A61L2202/15—Biocide distribution means, e.g. nozzles, pumps, manifolds, fans, baffles, sprayers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/23—Containers, e.g. vials, bottles, syringes, mail
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides the Antipollution method of a kind of spray bottle, make the clathrate containing quintessence oil, then on the bottle cap inwall of spray bottle, it is provided for the medicine box of accommodating clathrate, clathrate is placed in medicine box so that quintessence oil volatilizees in the inside of spray bottle, wherein, described clathrate is mixed to form with inclusion agents by quintessence oil, or is carried on carrier formation by quintessence oil.The Antipollution method that the present invention provides uses the quintessence oil of natural botanical source to replace common synthesis antibacterial, and toxic and side effects is less, and safety is more preferable；Quintessence oil is fabricated to the clathrate with slow release characteristic, can be extended it and use effect so that it is for a long time, play consistently effect；Essential oil clathrate is placed in the bottle cap of spray bottle, can avoid producing impact with material in bottle, antibacterial environment can be formed in spray bottle, thus solve the microbiological contamination problem at microbiological contamination problem, especially nozzle；The method raw material sources of the present invention are extensive, and manufacture method is easy, has very much the potentiality of large-scale application.
Description
Technical field
The present invention relates to field of medical technology, be specifically related to the Antipollution method of a kind of spray bottle.
Background technology
Spray bottle is a kind of common medical, living utensil, can be used to contain medicine, food, cosmetics etc..Due to spraying
Be mostly aqueous liquid component in Ping, be therefore very easy to breed bacteria, contact the most at first the external world position (bottleneck,
Nozzle etc.) because the index that may present that the residual of liquid makes microbiological contamination rises.
For some spray products needing life-time service, for suppressing its microbiological contamination, conventional method is to spray bottle
In liquid in add antibacterial, but this way there may be following hidden danger: first, the antibacterial overwhelming majority is industry
Synthesis (such as: benzalkonium chloride, benzalkonium bromide etc.) product, may have undesirable effect user；Second, the bottle of spray bottle
Contact external environment due to altofrequency at mouth, nozzle, only rely on the antibacterial in residual liquid and cannot play enough antibacterial effects
Really；3rd, whether the antibacterial that endogenous adds can produce chemical action with liquid in spray bottle and to affect product property the most difficult
With precognition.
Summary of the invention
For the defect overcoming existing spray bottle to exist at aspects such as easy microbiological contaminations, it is an object of the invention to provide a kind of spray
The Antipollution method of mist bottle.
The Antipollution method of the spray bottle that the present invention provides includes: make the clathrate containing quintessence oil, then in described spray
Be provided for the medicine box of accommodating described clathrate on the bottle cap inwall of mist bottle, the clathrate of gained is placed in described medicine box so that
Quintessence oil volatilizees in the inside of described spray bottle, and wherein, described clathrate is mixed to form with inclusion agents by described quintessence oil, or passes through
Described quintessence oil is carried on carrier formation.
In Antipollution method of the present invention, described inclusion agents can be selected for cyclodextrin and derivant thereof, carbamide, thiourea,
Deoxycholic acid or glucosan.
Preferably, described cyclodextrin and derivant thereof selected from alpha-cyclodextrin, beta-schardinger dextrin-, gamma-cyclodextrin, hydroxy propyl-Beta-
Cyclodextrin, hydropropyl-y-cyclodextrin, methyl-B-cyclodextrin, carboxymethyl-beta-cyclodextrin, hydroxyl fourth group-beta-cyclodextrin, ethoxy
One or more in cyclodextrin, ethyl cyclodextrin, polymeric cyclodextrins, branched cyclodextrin.Also can be selected for existing any modification
Cyclodextrin kind.
In Antipollution method of the present invention, described quintessence oil can change according to actual needs with the consumption of described inclusion agents
Becoming, preferred mass ratio can be 0.01～10:100.
In Antipollution method of the present invention, the inclusion type clathrate preparation process that quintessence oil and inclusion agents are formed is permissible
For: by inclusion agents suitable quantity of water or solvent dilution, grind to form pasty state, more uniform with quintessence oil mixed grinding, volatilize water or solvent obtains
To dry extract, then grind to form fine powder, to obtain final product.
In Antipollution method of the present invention, described carrier is selected from absorbent paper, and described absorbent paper can be natural material,
Can also be for synthesis macromolecule material, such as materials such as non-woven fabrics, high quality cotton, natural fiber material, dust-free papers.Preferably, described
Absorbent paper is selected from Wen Xiangzhi.
In Antipollution method of the present invention, the support type clathrate preparation process that quintessence oil and carrier are formed can be:
The quintessence oil solution of configuration finite concentration (can be such as 0.1～10%), is then placed in solution certain time (such as by carrier
Can be 30min, or longer) carry out quintessence oil load, to obtain final product.
In Antipollution method of the present invention, described quintessence oil can be selected from any kind with bacteriostasis, such as
Quintessence oil selected from extracting from following plant: Herba thymi vulgaris, lavandula angustifolia, Herba Ocimi (Herba Ocimi Pilosi), Citrus, eucalyptus globolus, Herba Menthae, Herba Verbenae, Flos Inulae, fourth
Perfume, coffee, Fructus Foeniculi, hyssop, Herba Cymbopogonis Citrari, myrtus communis, Flos Osmanthi Fragrantis, Cymbopogon martini, pine, Luo Wenshaye, rosewood, Mentha viridis L, Radix Et Rhizoma Nardostachyos, ten thousand
Longevity chrysanthemum or Camellia sinensis.
In Antipollution method of the present invention, described medicine box can be provided with one or more passage, so that quintessence oil
Volatilization produces bacteriostasis.
In Antipollution method of the present invention, described medicine box can also be closed structure, and the bottom of described spray bottle sets
It is equipped with sharp portion, in order to puncture described medicine box so that described quintessence oil volatilizees in the inside of described spray bottle.
Further, the bottom of described spray bottle is additionally provided with shielding block, in order to cover described sharp portion.
The Antipollution method that the present invention provides has the advantage that
(1) quintessence oil using natural botanical source replaces common synthesis antibacterial, for user toxic and side effects more
Little, safety is more preferable.
(2) quintessence oil is fabricated to the clathrate with slow release characteristic, can be extended it and use effect so that it is be long-time, steady
Surely play a role.
(3) essential oil clathrate is placed in the bottle cap of spray bottle, can avoid producing impact with material in bottle, can be in spraying
Form antibacterial environment in bottle, thus solve the microbiological contamination problem at microbiological contamination problem, especially nozzle.
(4) Antipollution method of the present invention has also carried out structure improvement to common spray bottle, makes making of essential oil clathrate
With convenient, safely, effectively.
(5) the method raw material sources of the present invention are extensive, and manufacture method is easy, has very much the potentiality of large-scale application.
Accompanying drawing explanation
Fig. 1 is the internal structure schematic diagram at the spray bottle nozzle of the present invention；
Fig. 2 is spray bottle polycrystalline substance schematic diagram (without shielding block) of the present invention；
Fig. 3 is spray bottle polycrystalline substance schematic diagram (containing shielding block) of the present invention；
Wherein, description of reference numerals is as follows: 1, spray bottle；2, medicine box；3, essential oil clathrate；4, sharp portion；5, shielding block.
Detailed description of the invention
Following example, with selecting quintessence oil only as a example by Herba thymi vulgaris, can select the quintessence oil that other kinds are suitable as required.
Embodiment 1
| Thyme oil | 0.01g |
| HP-β-CD | 100g |
| Distilled water | 50ml |
Preparation method:
Accurately weigh 100g HP-β-CD in mortar, to add suitable quantity of water be ground into pasty state, take thyme oil 0.01g and put and grind
In alms bowl, after grinding uniformly, stop, being dried, obtain dry extract, then grind to form fine powder, pelletize, obtain the HP-β-CD of volatile oil
Clathrate.
Embodiment 2
Preparation method:
Accurately weigh 100g HP-β-CD in mortar, to add suitable quantity of water be ground into pasty state, take thyme oil 0.1g and put mortar
In, after grinding uniformly, stop, being dried, obtain dry extract, then grind to form fine powder, pelletize, obtain the HP-β-CD bag of volatile oil
Compound.
Embodiment 3
| Thyme oil | 1g |
| HP-β-CD | 100g |
| Distilled water | 50ml |
Preparation method:
Accurately weigh 100g HP-β-CD in mortar, to add suitable quantity of water be ground into pasty state, take thyme oil 1g and put mortar
In, after grinding uniformly, stop, being dried, obtain dry extract, then grind to form fine powder, pelletize, obtain the HP-β-CD bag of volatile oil
Compound.
Embodiment 4
| Thyme oil | 10g |
| HP-β-CD | 100g |
| Distilled water | 50ml |
Preparation method:
Accurately weigh 100g HP-β-CD in mortar, to add suitable quantity of water be ground into pasty state, take thyme oil 10g and put mortar
In, after grinding uniformly, stop, being dried, obtain dry extract, then grind to form fine powder, pelletize, obtain the HP-β-CD bag of volatile oil
Compound.
Embodiment 5
| Thyme oil | 0.1% |
| Hear fragrant paper |
Preparation method:
Wen Xiangzhi is soaked in confined conditions in 0.1% thyme oil solution after 30 minutes, takes out, be dried, i.e.
?.
Embodiment 6
| Thyme oil | 3% |
| Hear fragrant paper |
Preparation method:
Wen Xiangzhi is soaked in confined conditions in 3% thyme oil solution after 30 minutes, takes out, be dried, to obtain final product.
Embodiment 7
| Thyme oil | 10% |
| Absorbent paper |
Preparation method:
Wen Xiangzhi is soaked in confined conditions in 10% thyme oil solution after 30 minutes, takes out, be dried, i.e.
?.
The essential oil clathrate of the present invention can be used for any type of spray bottle, such as, spray bottle 1 as shown in Figure 1, bottle cap
Be internally provided with medicine box 2, for preventing the moving influence essential oil clathrate 3 of medicine box 2 from playing a role, medicine box 2 is preferably fixedly installed
In bottle cap.Spray bottle 1 can be the structure that bottle cap separates with bottle, it is possible to be structure as a whole, and now, medicine box 2 may be disposed at
Nozzle top, so that its performance is antibacterial, especially antibacterial at nozzle function.
Essential oil clathrate 3 is placed among medicine box 2, for making quintessence oil volatilize, medicine box 2 can arrange one to multiple passages.
It addition, be the effect keeping quintessence oil further, medicine box 2 may also set up the structure becoming sealing, punctured formation when deployed
Passage for quintessence oil volatilization.As in figure 2 it is shown, may also set up the structure for puncturing medicine box 2 on spray bottle, such as, it it can be the end
One sharp portion 4 in portion.As it is shown on figure 3, for preventing sharp portion 4 from scratching user, shielding block 5 also can be arranged on sharp portion 4.
<bacteriostatic activity checking test>
1, sample and test method
Take the news perfume (or spice) scraps of paper (sample 1, prepared by embodiment 5 method) containing thyme oil respectively and containing Isodose
The clathrate (sample 2, prepared by embodiment 1 method) of thyme oil as examination group, and by above-mentioned 2 samples respectively in connection with in
Upper wall in spray bottle bottle cap, simultaneously using upper wall zero load in bottle cap as blank group (sample 3).Above 3 spray bottles, bottle inner canister
The liquid of dress is purified water.After every bottle sprays 30 times, cover bottle cap, place.After one week, every bottle at nozzle spray take spraying 1ml,
Do microorganism count.
2, method and conclusion
Take the solution to be measured of above-mentioned 3 kinds of samples, check according to microbial limit test, the results are shown in Table 1.
Table 1
| Sample | Bacterial population (cfu/ml) |
| Sample 1 | 0 |
| Sample 2 | 40 |
| Sample 3 | ＞ 100 |
Result shows, in bottle cap, the spray bottle containing essential oil clathrate of the present invention all can effectively suppress bottle content
The microbial growth of thing, and inhibition is the most notable.Found by contrast that bottle cap has the spray bottle of essential oil clathrate simultaneously
To the spray bottle not containing essential oil clathrate in the inhibitory action bottle cap to be substantially better than of bottle content microbial growth.And
And, the essential oil clathrate of the present invention, without extra antibacterial, eliminates potential safety hazard, and preparation is simple.
Unless limited otherwise, term used herein is the implication that those skilled in the art are generally understood that.
Embodiment described in the invention is merely for exemplary purpose, and is not used to limit the scope of the invention,
Those skilled in the art can be made within the scope of the invention various other replacement, changes and improvements, thus, the invention is not restricted to
Above-mentioned embodiment, and be only defined by the claims.
Claims (10)
1. the Antipollution method of a spray bottle, it is characterised in that make the clathrate containing quintessence oil, then at described spray bottle
Bottle cap inwall on be provided for the medicine box of accommodating described clathrate, the clathrate of gained is placed in described medicine box so that quintessence oil
Volatilizing in the inside of described spray bottle, wherein, described clathrate is mixed to form with inclusion agents by described quintessence oil, or by described
Quintessence oil is carried on carrier formation.
Antipollution method the most according to claim 1, it is characterised in that described inclusion agents is selected from cyclodextrin and derives
Thing, carbamide, thiourea, deoxycholic acid or glucosan.
Antipollution method the most according to claim 2, it is characterised in that described cyclodextrin and derivant thereof are stuck with paste selected from α-ring
Essence, beta-schardinger dextrin-, gamma-cyclodextrin, HP-β-CD, hydropropyl-y-cyclodextrin, methyl-B-cyclodextrin, carboxymethyl-
In beta-schardinger dextrin-, hydroxyl fourth group-beta-cyclodextrin, hydroxyethyl cyclodextrin, ethyl cyclodextrin, polymeric cyclodextrins, branched cyclodextrin one
Plant or multiple.
Antipollution method the most according to claim 2, it is characterised in that described quintessence oil with the mass ratio of described inclusion agents is
0.01～10:100.
Antipollution method the most according to claim 1, it is characterised in that described carrier is selected from absorbent paper.
Antipollution method the most according to claim 5, it is characterised in that described absorbent paper is selected from Wen Xiangzhi.
Antipollution method the most according to claim 1, it is characterised in that described quintessence oil is selected from the essence extracting from following plant
Oil: Herba thymi vulgaris, lavandula angustifolia, Herba Ocimi (Herba Ocimi Pilosi), Citrus, eucalyptus globolus, Herba Menthae, Herba Verbenae, Flos Inulae, Flos Caryophylli, coffee, Fructus Foeniculi, hyssop, perfume (or spice)
Thatch, myrtus communis, Flos Osmanthi Fragrantis, Cymbopogon martini, pine, Luo Wenshaye, rosewood, Mentha viridis L, Radix Et Rhizoma Nardostachyos, Flos Tagetis Erectae or Camellia sinensis.
Antipollution method the most according to claim 1, it is characterised in that be provided with one or more ventilation on described medicine box
Hole.
Antipollution method the most according to claim 1, it is characterised in that described medicine box is closed structure, described spray bottle
Bottom be provided with sharp portion, in order to puncture described medicine box so that described quintessence oil in the inside of described spray bottle volatilize.
Antipollution method the most according to claim 9, it is characterised in that the bottom of described spray bottle is additionally provided with covers
Block, in order to cover described sharp portion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610532138.5A CN106178035A (en) | 2016-07-07 | 2016-07-07 | A kind of Antipollution method of spray bottle |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610532138.5A CN106178035A (en) | 2016-07-07 | 2016-07-07 | A kind of Antipollution method of spray bottle |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106178035A true CN106178035A (en) | 2016-12-07 |
Family
ID=57473114
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610532138.5A Pending CN106178035A (en) | 2016-07-07 | 2016-07-07 | A kind of Antipollution method of spray bottle |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106178035A (en) |
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| CB03 | Change of inventor or designer information |
Inventor after: Liang Xiao Inventor after: Xin Yan Inventor after: Liu Xuan Inventor after: Liu Weiwei Inventor before: Xin Yan Inventor before: Liu Xuan Inventor before: Liu Weiwei |
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| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20161207 |