CN106177711A - A kind of medicine for treating postcerebral injury syndrome - Google Patents

A kind of medicine for treating postcerebral injury syndrome Download PDF

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Publication number
CN106177711A
CN106177711A CN201610700096.1A CN201610700096A CN106177711A CN 106177711 A CN106177711 A CN 106177711A CN 201610700096 A CN201610700096 A CN 201610700096A CN 106177711 A CN106177711 A CN 106177711A
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medicine
fructus alpiniae
alpiniae oxyphyllae
treating
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吴斌
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9062—Alpinia, e.g. red ginger or galangal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/62—Nymphaeaceae (Water-lily family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
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  • Alternative & Traditional Medicine (AREA)
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Abstract

The present invention relates to a kind of medicine for treating postcerebral injury syndrome, it is to be prepared from by the raw medicinal material of following weight proportion: 7 parts of Semen Persicae, Folium Ilicis Cornutae 2 parts, 4 parts of Folium Nelumbinis, Poria cum Radix Pini 4 parts, Flos Albiziae 7 parts, Fructus Alpiniae Oxyphyllae 6 parts, phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle skin eat 7 parts, Herba Pugionii Cornuti 30 parts.This present invention uses: Semen Persicae blood circulation promoting and blood stasis dispelling；Folium Ilicis Cornutae reinforcing spleen and kidney, YIN nourishing and the production of body fluid promoting；Folium Nelumbinis sending up the lucid YANG；Poria cum Radix Pini's mind tranquilizing and the heart calming；Flos Albiziae resolving stagnation for tranquilization；Fructus Alpiniae Oxyphyllae benefit essence fills out marrow, brain-care；Phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle skin eats removing heat-phlegm；Herba Pugionii Cornuti promoting flow of QI and blood.All medicines share, and reach blood circulation promoting and blood stasis dispelling reinforcing spleen and kidney, YIN nourishing and the production of body fluid promoting, sending up the lucid YANG, the effect of Fructus Alpiniae Oxyphyllae of calming the nerves simultaneously.Clinical trial certificate, the present invention can safely and effectively treat postcerebral injury syndrome.

Description

A kind of medicine for treating postcerebral injury syndrome
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of medicine for treating postcerebral injury syndrome.
Background technology
Postcerebral injury syndrome is the performance after common injury of head.Often show as head injuries after 3 months, still deposit Or a series of neuropsychic symptoms of occurring, patient show as headache, dizzy, tired, sleep disorder, hypomnesis, Energy is not good and ability to work declines, nervous, hyperhidrosis, sexual disorder etc..Neurologic check does not has positive sign.
For subjective symptom is heavier, objective sign lacks such as or slight the clinical characters of post-traumatic syndrome, mainly headache, Dizzy and nervous system dysfunction etc. shows.
Headache is most commonly seen symptom, can be sharp pain, dull pain, throbbing pain, may alternatively appear in whole head, forehead Or occipitalia.The pain of occipitalia generally entails pain and the tension of muscle after neck.The time of Headache attacks is uncertain, can be because of emotion The best, tired, insomnia and increase the weight of, and therefore lather.One clear and definite reason of chronic post-traumatic headache is the forfeiture of cerebrospinal fluid, Hypotensive cranial pressure is caused to cause headache.But, most of persistence, the most serious cerebrospinal fluid person of leaking outside is the most significantly Headache, therefore, the excess generation of cerebrospinal fluid, it is fully able to supplement the quantity of loss.
Dizzy performance is of all kinds, often tells as having a dizzy spell, tinnitus, feels sick, increases the weight of because of position chanP.Neural Allergy and irritability are also the most common, typically by caused by nervous environmental factors.It addition, hypomnesis, attention are difficult The result of psychological factor effect it is probably with concentration, fatiguability, hypophrenia, insomnia etc..
What autonomic nervous function was lacked of proper care shows as cardiopalmus, fluctuation of blood pressure, hyperhidrosis, menoxenia, sexual dysfunction etc..
Having document to report, the symptom of craniocerebral injury is sometimes relevant to injury.The injured rear symptom of forehead is less；Temples is hindered After there are about more than half dizziness, dysmnesia occur；And attention concentrates difficulty, nervousness, fatiguability to be more common in outside top The wounded.
Medical material involved in the present invention all seen from be recorded in " China book on Chinese herbal medicine ".
Summary of the invention
It is desirable to provide a kind of medicine for treating postcerebral injury syndrome, by select suitable medical material and Proportioning, reaches safely and effectively to cure the purpose of postcerebral injury syndrome.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of medicine for treating postcerebral injury syndrome, it is characterised in that it is by the raw medicinal material of following weight proportion It is prepared from: 7 parts of Semen Persicae, Folium Ilicis Cornutae 2 parts, 4 parts of Folium Nelumbinis, Poria cum Radix Pini 4 parts, Flos Albiziae 7 parts, Fructus Alpiniae Oxyphyllae 6 parts, phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle skin eat 7 parts, sand 30 parts of mustard.
Illustrate the method have the benefit that below in conjunction with theories of Chinese materia medica
It has been recognised by the inventors that brain is " house of mental activity ", brain flows in may result in stagnant blood after causing injury because of extraneous violence strike, the blood flow stasis of blood Stagnant, brain is not filled, and then the series of symptoms such as headache, dizziness occurs.But after serious disease, the moon of consumption impairment of the spleen kidney, kidney governing bones, raw Marrow, brain being the marrow sea, suffer from a deficiency of the kidney, marrow nourishing bone can not be given birth to；Or weakness of the spleen and stomach, dysfunction of the spleen in transportation and transformation, so that clear sun is not all right, turbid YIN failing to descend, pathogenic fluid-retention Upper criminal, stops poly-intracranial；Therefore if blood circulation promoting and blood stasis dispelling is taked merely in treatment, curative effect is the most bad, palpus reinforcing spleen and kidney simultaneously, and YIN nourishing and the production of body fluid promoting rises Send out clear sun, Fructus Alpiniae Oxyphyllae of calming the nerves.
The present invention uses: Semen Persicae blood circulation promoting and blood stasis dispelling；Folium Ilicis Cornutae reinforcing spleen and kidney, YIN nourishing and the production of body fluid promoting；Folium Nelumbinis sending up the lucid YANG；Poria cum Radix Pini's mind calming Calm the nerves；Flos Albiziae resolving stagnation for tranquilization；Fructus Alpiniae Oxyphyllae benefit essence fills out marrow, brain-care；Phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle skin eats removing heat-phlegm；Herba Pugionii Cornuti promoting flow of QI and blood.All Medicine share, and reaches blood circulation promoting and blood stasis dispelling reinforcing spleen and kidney, YIN nourishing and the production of body fluid promoting, sending up the lucid YANG, the effect of Fructus Alpiniae Oxyphyllae of calming the nerves simultaneously.
Below in conjunction with clinical laboratory data beneficial effects of the present invention is described:
1, physical data
Inventor collects 44 example postcerebral injury syndrome patients altogether between in January ,-2015 in March, 2012.It is randomly divided into: treatment group 22 Example, matched group 22 example.Male 10 examples of wherein treatment group, female 12 example, age 18～38 years old, the course of disease 1～14 years；Matched group man 7 examples, female 15 examples, between age 19～43 years old, the course of disease 1～15 years.The data such as two groups of sexes, age, courses of disease there was no significant difference, and has comparable Property.
1. inclusive criteria makes a definite diagnosis the state of an illness；2. age 18-70 year；3. compliance is good；Sign Informed Consent Form the most voluntarily.
Exclusion standard 1. gestation, women breast-feeding their children；2. suffer from severe cardiac, lung, liver, renal disease patient；3. there are other essences God's systemic disease, it is impossible to partner treatment person；4. through the patient of other drug treatment after morbidity.
2, Therapeutic Method
Treatment group is administered orally the capsule that the present invention prepares according to specific embodiment 3, three times a day.Treat 1 month.
Matched group is administered orally oryzanol 40mg, piracetam 0.4 g and cinnarizine 50mL every time, three times a day..Treat 1 month.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
1. recovery from illness: giddy, headache, hypomnesis, absent minded, forgetful, insomnia, appetite decline, tinnitus, dizziness etc. are faced Bed transference cure, disease feelings consolidate more than 1 year；
The most effective: giddy, headache, hypomnesis, absent minded, forgetful, insomnia, appetite decline, tinnitus, dizziness etc. are faced Bed symptom alleviates；
The most invalid: symptom and sign all deteriorate without improving or continuing.
3.2 treatment statistical results are shown in Table 1.
1 liang of table group comparitive study
Group n Recovery from illness Effectively Invalid Total effective rate (%) Obvious adverse reaction example
Treatment group 22 10 8 4 82% 0
Matched group 22 6 7 9 59% 0
Visible, postcerebral injury syndrome can safely and effectively be treated by the medicine that the present invention prepares, and cure rate is high.
Detailed description of the invention
In order to be more fully understood that and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Weigh: 7 grams of Semen Persicae, Folium Ilicis Cornutae 2 grams, 4 grams of Folium Nelumbinis, Poria cum Radix Pini 4 grams, Flos Albiziae 7 grams, Fructus Alpiniae Oxyphyllae 6 grams, phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle skin eat 7 grams, sand 30 grams of mustard；Add 8 times amount water, decoct 1.5 hours, filter；Filtering residue adds 6 times amount water, decocts 1 hour, filters；Merging filtrate, concentrates To 120 grams, the decoct of one day consumption of adult normal must be met.
For treating postcerebral injury syndrome.Oral, the most once.
Embodiment 2
Weigh: 7 grams of Semen Persicae, Folium Ilicis Cornutae 2 grams, 4 grams of Folium Nelumbinis, Poria cum Radix Pini 4 grams, Flos Albiziae 7 grams, Fructus Alpiniae Oxyphyllae 6 grams, phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle skin eat 7 grams, sand 30 grams of mustard；Add 10 times amount water, decoct 2 hours, filter；Filtering residue adds 8 times amount water, decocts 1.5 hours, filters；Merging filtrate is dense Contracting, is dried, and packaging must meet the powder of one day consumption of adult normal.
For treating postcerebral injury syndrome.Oral, every bu is taken for twice sooner or later.
Embodiment 3
Weigh: 7 grams of Semen Persicae, Folium Ilicis Cornutae 2 grams, 4 grams of Folium Nelumbinis, Poria cum Radix Pini 4 grams, Flos Albiziae 7 grams, Fructus Alpiniae Oxyphyllae 6 grams, phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle skin eat 7 grams, sand 30 grams of mustard；Add 6 times amount water, decoct 3 times, decoct 1 hour every time, merge decoction liquor, concentrate, be dried, load capsule shells, obtain symbol Close the capsule of one day consumption of adult normal.
For treating postcerebral injury syndrome.Oral, every bu morning, noon and afternoon take for three times.

Claims (4)

1. the medicine being used for treating postcerebral injury syndrome, it is characterised in that it is by the crude drug of following weight proportion Material is prepared from: 7 parts of Semen Persicae, Folium Ilicis Cornutae 2 parts, 4 parts of Folium Nelumbinis, Poria cum Radix Pini 4 parts, Flos Albiziae 7 parts, Fructus Alpiniae Oxyphyllae 6 parts, phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle skin eat 7 parts, Herba Pugionii Cornuti 30 parts.
2. the medicine for treating postcerebral injury syndrome as claimed in claim 1, it is characterised in that its preparation method is: Weigh: 7 parts of Semen Persicae, Folium Ilicis Cornutae 2 parts, 4 parts of Folium Nelumbinis, Poria cum Radix Pini 4 parts, Flos Albiziae 7 parts, Fructus Alpiniae Oxyphyllae 6 parts, phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle skin eat 7 parts, Herba Pugionii Cornuti 30 Part；Add 8 times amount water, decoct 1.5 hours, filter；Filtering residue adds 6 times amount water, decocts 1 hour, filters；Merging filtrate, is concentrated into 120 Part, obtain decoct；Above-mentioned part each means weight portion.
3. the medicine for treating postcerebral injury syndrome as claimed in claim 1, it is characterised in that its preparation method is: Weigh: 7 parts of Semen Persicae, Folium Ilicis Cornutae 2 parts, 4 parts of Folium Nelumbinis, Poria cum Radix Pini 4 parts, Flos Albiziae 7 parts, Fructus Alpiniae Oxyphyllae 6 parts, phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle skin eat 7 parts, Herba Pugionii Cornuti 30 Part；Add 10 times amount water, decoct 2 hours, filter；Filtering residue adds 8 times amount water, decocts 1.5 hours, filters；Merging filtrate, concentrates, dry Dry, packaging, obtain powder；Above-mentioned part each means weight portion.
4. the medicine for treating postcerebral injury syndrome as claimed in claim 1, it is characterised in that its preparation method is: Weigh: 7 parts of Semen Persicae, Folium Ilicis Cornutae 2 parts, 4 parts of Folium Nelumbinis, Poria cum Radix Pini 4 parts, Flos Albiziae 7 parts, Fructus Alpiniae Oxyphyllae 6 parts, phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle skin eat 7 parts, Herba Pugionii Cornuti 30 Part；Add 6 times amount water, decoct 3 times, decoct 1 hour every time, merge decoction liquor, concentrate, be dried, load capsule shells, obtain capsule Agent；Above-mentioned part each means weight portion.
CN201610700096.1A 2016-08-23 2016-08-23 A kind of medicine for treating postcerebral injury syndrome Pending CN106177711A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103784746A (en) * 2014-02-08 2014-05-14 孙永国 Traditional Chinese medicinal composition for treating post-traumatic brain syndrome

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103784746A (en) * 2014-02-08 2014-05-14 孙永国 Traditional Chinese medicinal composition for treating post-traumatic brain syndrome

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