CN104587396A - Preparation for preventing dizziness caused by power overhead operation - Google Patents

Abstract

The invention relates to a preparation for preventing dizziness caused by power overhead operation. The preparation is prepared from the following raw materials in parts by weight: 35 parts of rhizoma atractylodis macrocephalae, 35 parts of fructus ligustri lucidi, 35 parts of radix puerariae, 30 parts of rhizoma alismatis, 30 parts of herba agrimoniae, 30 parts of rhizoma acori tatarinowii, 25 parts of radix glycyrrhizae, 25 parts of radix achyranthis bidentatae, 25 parts of folium nelumbinis, 25 parts of semen cassiaesemen cassiae, 22 parts of poria, 22 parts of radix ophiopogonis, 20 parts of radix ginseng rubra, 20 parts of radix rubiae, 20 parts of olibanum, 18 parts of indigo naturalis, 15 parts of radix polygoni multiflori, 15 parts of radix polygoni multiflori, 10 parts of cortex magnoliae officinalis, 10 parts of rhizoma curcumae, 7 parts of folium ginkgo, 7 parts of folium ginkgo, 7 parts of semen myristicae and 5 parts of semen strychni. The preparation can treat both symptoms and root causes of the dizziness, has no toxicity and injury and no side effects, and is low in price, simple and convenient to prepare, and wide in prospects.

Description

For the preparation preventing electric power work high above the ground dizzy

Technical field

The invention belongs to medical art, relate to a kind of for dizzy preparation, more specifically, it relates to a kind of preparation for preventing electric power work high above the ground dizzy.

Background technology

Dizzy is the one property moved because body produces planotopokinesia or positional illusion, and it relates to multiple subject.Most people all experiences this disease in life, and power construction to have open work many, work high above the ground is many, the features such as labor intensity is large, high-altitude electric operating, away from the tens of rice in ground, transfer to other use as acrobat, work, only have palm wide with stopping over, gingerly, camp step by step forever.As the power worker being responsible for work high above the ground specially, generally, have every month within 20 days, all obtain creepage tower or electric pole, if and run into duration tighter project, except sleep of having a meal, all the other all times all will treat on tower, and seven or eight hours every days, foot did not land.Some work high above the ground persons stand in eminence and look down, and will produce a kind of probably all psychology, worry to throw and can lose one's life, thus more worry more panic, cold sweat directly emits, and two lower limbs are aching and limp trembles; And after the others's work high above the ground a period of time, just there will be pale complexion, astasia, the symptom such as very dizzy, this is all dizzy symptom in fact,

Dizzy, be a kind of common symptom clinically.This disease can recurrent exerbation, and the lighter is as sat journey, and the time of outbreak is of short duration, and namely the flat sleeping order that closes pacifies a moment; Namely severe one feels very dizzy, can not stand, the symptoms such as companion sees nausea and vomiting, is in a cold sweat, hand shaking, and especially easily occur in it fat, the poor person of body and old people, patient feels " fluttering is swung ", does not clearly rotate sense.Patient is to the subjective mistake known from experience of spatial orientation sensation, and patient feels surrounding objects or from rotation, or is oscilaltion, the sensation that rolls.The patient suffering from vertigo has following symptom usually: blood pressure, perspires, pale complexion, diarrhoea; Deafness, tinnitus, ear is vexed; Dark and dim eyesight, diplopia, blurred vision; Neck portion or shoulder arm pain, upper limb numbness, limitation of activity; Headache, disturbance of consciousness, sensorimotor obstacle, language or dysarthria etc., doctor trained in Western medicine generally adopts symptomatic treatment, and is treated respectively for underlying diseases.

Clinical common many uses calmness and tranquilizer, blood vessel dilating agent, anticholinergic agents, antihistamine drug and anesthetis etc.Because said medicine has the side effect such as drowsiness, xerostomia mostly, most of patients is more prone to seek treatment by Chinese herbs safely and effectively.

The traditional Chinese medical science has very long history for dizzy treatment, and have accumulated rich experience in practice, motherland's medical science is thought dizzy and can be caused by wind, expectorant, wet, void, therefore have the saying of " calm do not do dizzy ", " dizziness must be caused by phlegm ", " dizziness must be due to deficiency ", dizzyly many to fall ill because of reasons such as dynamic in patient's excess of YANG hyperactivity of fire or empty positive rising usually, wind sun, stagnation of turbid phlegm in middle-JIAO, deficiency of QI in middle-JIAO, deficiency of kidney-essence, treatment is stopped burning with fresh breeze, blood stasis dispelling of eliminating the phlegm, nourish yin and calm the liver, kidney tonifying, essence replenishing be essential therapeutic arsenals.Successive dynasties doctor nationality is recorded a lot of, as: " Plain Questions the most pure virginity will be discussed greatly " is thought: " all wind trembling and dizziness, all belong to liver "; " the large puzzled opinion of bier " is pointed out: " in item in old pathogen; because meeting the void of its body ... enter brain then vertigo; it is anxious that vertigo then draws order system; order system is anxious then dizzy to turn, " pathogenic factor long term in cervical vertebra, general debility with deficiency of QI in addition, skeleton regression, cause neck blood stasis, passages through which vital energy circulates loses supports, and causes all diseases such as dizzy, stiffness of the nape to occur; " Ling Shu Miraculous Pivot or Divine Axis defends gas " is thought: " deficiency of the upper causing dizziness ", also has " QI of the upper portion of the body being insufficient " in Miraculous Pivot, and " deficiency of marrow-reservoir " etc. cause dizzy because of void.Han dynasty Zhang Zhongjing thinks that phlegm retention is one of reason of dizzy morbidity, had again six climate exopathogens afterwards, damaged by excess of seven emotions causes dizzy, and dificiency in lower-JIAO causes dizzy etc.According to clinical practice, dizzy in close relations with the liver of theory of Chinese medical science.Excessive rising of liver-YANG can directly be sent out dizzy, or because of long-term melancholy angry, stagnated QI transforming into fire, makes liver-yin secretly consume, and wind sun rises dynamic, and pathogen upward attacking orifices in head is sent out as dizzy, or chronic deficiency of kidney-YIN, the liver failing to be nourished, so that deficiecny of liver-YIN, and excessive rising of liver-YANG is sent out as dizzy.But it is very inconvenient that Chinese medicine decoction uses, and has been difficult to extensive patients and accepted, in addition, the dizzy Chinese medicine of existing treatment is very limited, far can not meet clinical application demand.

Summary of the invention

The object of this invention is to provide that a kind for the treatment of both the principal and secondary aspects of a disease, side effect are little, safe ready, cheap prevent dizzy preparation.Its objective is to solve treatment vertigo, especially, invention formulation is applicable to dizzy electric power work high above the ground occurred frequently, and it may be used for treatment work high above the ground vertigo, also can dizzy effectively in prevention work, the risk factor of reduction work high above the ground.

The present invention is with reference to the motherland medical science invaluable experience to the pathogenetic understanding of vertigo and treatment, consult existing reasonable formula, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, according to Chinese Pharmacopoeia and pharmacology compatibility, push away Chen Zhixin gain to some extent, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs is the core theory of Chinese medicine disease always, how to take into account secondary pathogenesis for main pathogenesis medication simultaneously, taking into account the treatment of general character and individual character, thus at utmost embody intension and the extension of Chinese traditional treatment disease, is a realistic problem of Chinese patent medicine compatibility.Inventor is for dizzy main pathogenesis characteristics, in conjunction with a large amount of formula according to doctor's row practice for many years, by the research to Chinese medicine, and in conjunction with dialectical demonstration, in many ways the length of many families is collected, seek therapeutic regimen, the natural drug of effect of benefiting QI and nourishing blood, promoting the flow of QI in the collateral by warming the meridian, Fuzheng Yiliu heresy is filtered out from motherland's medical treasure-house, treat the high and safe without toxic side effect of sudden dizzy cure rate, by theory of Chinese medical science prescription, skim the cream off milk, it is rapid-action, effect is strong, short treating period, safety are high, without obvious toxic-side effects.All medicines share, and bring out the best in each other.

For realizing the object of the invention, the technical solution used in the present invention is as follows:

For the preparation preventing electric power work high above the ground dizzy, it is prepared by following weight proportioning raw material and obtains:

The Rhizoma Atractylodis Macrocephalae 35 parts, Fructus Ligustri Lucidi 35 parts, Radix Puerariae 35 parts, Rhizoma Alismatis 30 parts, Herba Agrimoniae 30 parts,

Rhizoma Acori Graminei 30 parts, 25 parts, Radix Glycyrrhizae, Radix Achyranthis Bidentatae 25 parts, 25 parts, Folium Nelumbinis, Semen Cassiae 25 parts,

22 parts, Poria, Radix Ophiopogonis 22 parts, Radix Ginseng Rubra 20 parts, 20 parts, Radix Rubiae, Olibanum 20 parts,

Indigo Naturalis 18 parts, Radix Polygoni Multiflori 15 parts, Cortex Moutan 15 parts, Fructus Chaenomelis 15 parts, Cortex Magnoliae Officinalis 10 parts,

Rhizoma Curcumae 10 parts, Folium Ginkgo 7 parts, Semen Myristicae 7 parts, Semen Strychni 5 parts.

Its preparation method is:

1) raw material is taken according to weight proportion

2) Radix Puerariae, Rhizoma Alismatis, Herba Agrimoniae, Rhizoma Acori Graminei, Poria, Radix Ophiopogonis, Radix Ginseng Rubra, Radix Rubiae, Olibanum, Radix Polygoni Multiflori, Cortex Magnoliae Officinalis, Semen Strychni is got, add 3 times of weight 90% alcohol dipping 24 hours, reflux, extract, twice, each 1 hour, merge extractive liquid, is condensed into the clear paste that density is 1.2 g/ml;

3) get residual components water boiling and extraction 2 times, first time extracts the water adding 5 times of weight, and extraction time is 1 hour; Second time extracts the water adding 2 times of weight, and extraction time is 1 hour; Filter, merging filtrate, is concentrated into the clear paste that density is 1.2 g/ml;

4) by step 2), the clear paste prepared of step 3) mixes and get final product.

Medicine of the present invention can adopt the conventional method in existing pharmaceutical field to produce, and can add various pharmaceutically acceptable carrier when needs.Described carrier comprises the excipient, filler, binding agent, wetting agent, disintegrating agent, absorption enhancer, surfactant, absorption carrier, lubricant etc. of pharmaceutical field routine.

Preferably, make capsule according to a conventional method, every 0.1g, through being up to the standards as finished product.

Usage and dosage, one time 1,3 times on the one.

During for pre-anti-dazzle, within first two hours, take 1 in work high above the ground.

Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription, each drug component is through dialectical compatibility, complement each other using, there is synergism, play strengthening the spleen stomach function regulating altogether, effect of eliminating phlegm of having one's ideas straightened out, warming the meridian and promoting blood circulation, promoting blood circulation to remove blood stasis, thus the treatment of vertigo is reached to the object for the treatment of both the principal and secondary aspects of a disease.

The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.It follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopts decocting and takes after mixing it with water and takes.Through clinical practice checking, it is evident in efficacy, reliable effect, mild in medicine property and, there is not toxic and side effects.

Detailed description of the invention

Embodiment 1

For the preparation preventing electric power work high above the ground dizzy, it is characterized in that it is prepared by following weight proportioning raw material and obtains:

The Rhizoma Atractylodis Macrocephalae 35 parts, Fructus Ligustri Lucidi 35 parts, Radix Puerariae 35 parts, Rhizoma Alismatis 30 parts, Herba Agrimoniae 30 parts,

Rhizoma Acori Graminei 30 parts, 25 parts, Radix Glycyrrhizae, Radix Achyranthis Bidentatae 25 parts, 25 parts, Folium Nelumbinis, Semen Cassiae 25 parts,

22 parts, Poria, Radix Ophiopogonis 22 parts, Radix Ginseng Rubra 20 parts, 20 parts, Radix Rubiae, Olibanum 20 parts,

Indigo Naturalis 18 parts, Radix Polygoni Multiflori 15 parts, Cortex Moutan 15 parts, Fructus Chaenomelis 15 parts, Cortex Magnoliae Officinalis 10 parts,

Rhizoma Curcumae 10 parts, Folium Ginkgo 7 parts, Semen Myristicae 7 parts, Semen Strychni 5 parts.

Its preparation method is:

1) raw material is taken according to weight proportion

2) Radix Puerariae, Rhizoma Alismatis, Herba Agrimoniae, Rhizoma Acori Graminei, Poria, Radix Ophiopogonis, Radix Ginseng Rubra, Radix Rubiae, Olibanum, Radix Polygoni Multiflori, Cortex Magnoliae Officinalis, Semen Strychni is got, add 3 times of weight 90% alcohol dipping 24 hours, reflux, extract, twice, each 1 hour, merge extractive liquid, is condensed into the clear paste that density is 1.2 g/ml;

3) get residual components water boiling and extraction 2 times, first time extracts the water adding 5 times of weight, and extraction time is 1 hour; Second time extracts the water adding 2 times of weight, and extraction time is 1 hour; Filter, merging filtrate, is concentrated into the clear paste that density is 1.2 g/ml;

4) by step 2), step 3) prepare clear paste mixing, be pressed into soft capsule with encapsulating machine, every 0.1g, through being up to the standards as finished product.

Usage and dosage, one time 1,3 times on the one.

Embodiment 2

One, toxicity test

This experiment adopts healthy SD rat, medicine prepared by oral administration embodiment 1, successive administration 30 days, during observing rat administration and after drug withdrawal, within 1 week, growth of animal state, movable diet, hematology, blood biochemical analysis, organs and tissues structure and routine urinalysis etc. all have no significant effect, and show that clinical drug safety is reliable.

Two, invention formulation rotates rear property nystagmus to rat obvious inhibitory action, the tolerance time of vestibule irriate can be extended, alleviate vestibule autonomic nervous dysfunction, blood vessel dilating can be played, improve microcirculation, increase blood flow, alleviate dizzy and tinnitus, deaf effect;

Embodiment 3

Clinical data

1. choose outpatient's totally 82 examples with complete case.Patient feels that self or surrounding objects rotate, waves, floating sense, with diseases such as Nausea and vomiting, tinnitus, dysequilibrium, nystagmus, be divided into treatment group, matched group two groups at random, often organize 41 people, between group, age of patient, the course of disease and dizzy degree are basically identical, no significant difference (P>0.05), has comparability.

Treatment group give embodiment 1 prepare preparation, 3 times on the 1st, 1 time 1;

Matched group gives diphenidol tablet, 3 times on the 1st, 1 50mg;

All patients stops using the other medicines relevant to treating primary disease and other Therapeutic Method at treatments period.

Diagnostic criteria

1. tcm diagnosis

(1) typical vertigo symptoms is had: self have and rotate or rolling innervation, or what comes into a driver's thing has sense of rotation; Or conscious dizziness, dusk

Heavy or dizzy swollen discomfort.(2) history of repeated attack can be had.

2. Chinese medical discrimination

Stagnation of turbid phlegm in middle-JIAO is demonstrate,proved

Dizzy and see heaviness of the head as being covered, or sharply dizzy, self or scenery rotate, and body uncomfortable in chest is stranded, lack of appetite drowsirness, nausea and vomiting, Hiccough and deaf, white and greasy fur, the sliding or stringy and rolling pulse of soft pulse.

3. dizzy weight grade scale

(1) slight: consciously to have a dizzy spell, without self or scenery sense of rotation or shake dynamic; Or the murky and not shadow of simple head

It is movable to ring.

(2) moderate: conscious dizziness also has self to rotate or shakes dynamic, but does not affect life; Or simple dizzy and affect activity,

But can work be adhered to.

(3) severe: conscious dizziness also has self and scenery sense of rotation, and head body dare not rotate; Or dizzy merely, upset,

Be difficult to competent at a job.

Efficacy assessment standard:

1, clinical efficacy

Recovery from illness: treatment is dizzy afterwards waits transference cure.

Effective: after treatment, the symptom such as dizzy obviously alleviates, micro-have murky, or have a dizzy spell slight but without self and scenery rotation, shake dynamic, can orthobiosis and work.

Effective: dizzy or dizzyly to alleviate after treatment, only with slight self or scenery rotation, shake dynamic, though can adhere to

Work, but live and work is affected.

Invalid: the symptoms such as giddy is heavy and dizzy are without improvement or increase the weight of.

Result is as shown in table 1:

Table 1: efficacy result

Group	Example time	Recovery from illness	Effective	Effectively	Invalid	Total effective rate
							Treatment group	41	31	6	2	2	95.1％
Matched group	41	12	11	8	10	75.6％

Therefore the embodiment of the present invention 1 group is all significantly higher than matched group medicine in total effective rate and cure rate etc.

Embodiment 4

Exemplary embodiments

Military certain, man, 49 years old.Suffered from sudden dizzy before half a year, take a turn for the better by treatment.The overworked recurrence of cause on the 1st.Time medical, private prosecution is had a dizzy spell, with Nausea and vomiting, and pale complexion.Nausea and vomiting stopping after 1 day is treated in the pharmaceutical preparation giving embodiment 1 preparation, and after 2 days, symptom obviously alleviates.After continuing to take 3 days, symptom all disappears.

The application is for preventing dizzy preparation with low cost, evident in efficacy, has broad application prospects.

Claims (3)

1. the preparation for preventing electric power work high above the ground dizzy, is characterized in that, described preparation is prepared by the raw material of following weight proportioning and obtains:

The Rhizoma Atractylodis Macrocephalae 35 parts, Fructus Ligustri Lucidi 35 parts, Radix Puerariae 35 parts, Rhizoma Alismatis 30 parts, Herba Agrimoniae 30 parts,

Rhizoma Acori Graminei 30 parts, 25 parts, Radix Glycyrrhizae, Radix Achyranthis Bidentatae 25 parts, 25 parts, Folium Nelumbinis, Semen Cassiae 25 parts,

22 parts, Poria, Radix Ophiopogonis 22 parts, Radix Ginseng Rubra 20 parts, 20 parts, Radix Rubiae, Olibanum 20 parts,

Indigo Naturalis 18 parts, Radix Polygoni Multiflori 15 parts, Cortex Moutan 15 parts, Fructus Chaenomelis 15 parts, Cortex Magnoliae Officinalis 10 parts,

Rhizoma Curcumae 10 parts, Folium Ginkgo 7 parts, Semen Myristicae 7 parts, Semen Strychni 5 parts.

2. preparation according to claim 1, is characterized in that, the preparation method of described preparation comprises the steps:

1) each raw material is taken according to weight proportion;

2) Radix Puerariae, Rhizoma Alismatis, Herba Agrimoniae, Rhizoma Acori Graminei, Poria, Radix Ophiopogonis, Radix Ginseng Rubra, Radix Rubiae, Olibanum, Radix Polygoni Multiflori, Cortex Magnoliae Officinalis, Semen Strychni is got, mixing, add 90% alcohol dipping 24 hours of 3 times of weight, reflux, extract, twice, each 1 hour, merge extractive liquid, is condensed into the clear paste that density is 1.2 g/ml;

3) get surplus stock, mixing, by water boiling and extraction 2 times, first time extracts the water adding 5 times of weight, and extraction time is 1 hour; Second time extracts the water adding 2 times of weight, and extraction time is 1 hour; Filter, merging filtrate, is concentrated into the clear paste that density is 1.2 g/ml;

4) by step 2) and the clear paste prepared of step 3) mix and get final product.

3. preparation described in claim 1-2 is used for the dizzy therapeutic use of high-altitude electric operating.