CN106176478A - A kind of cosmetic composition and preparation method thereof - Google Patents

A kind of cosmetic composition and preparation method thereof Download PDF

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Publication number
CN106176478A
CN106176478A CN201610777398.9A CN201610777398A CN106176478A CN 106176478 A CN106176478 A CN 106176478A CN 201610777398 A CN201610777398 A CN 201610777398A CN 106176478 A CN106176478 A CN 106176478A
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China
Prior art keywords
cosmetic composition
sun
proof
alcohol
extract
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Chinese (zh)
Inventor
胡火明
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Guangzhou Qiaoqiao Biotechnology Co Ltd
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Guangzhou Qiaoqiao Biotechnology Co Ltd
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Priority to CN201610777398.9A priority Critical patent/CN106176478A/en
Publication of CN106176478A publication Critical patent/CN106176478A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/066—Multiple emulsions, e.g. water-in-oil-in-water
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A61K8/553—Phospholipids, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
    • A61K8/585—Organosilicon compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/602—Glycosides, e.g. rutin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/89—Polysiloxanes
    • A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/60—Particulates further characterized by their structure or composition
    • A61K2800/61—Surface treated
    • A61K2800/62—Coated
    • A61K2800/63—More than one coating

Abstract

The invention provides a kind of cosmetic composition, " the sun-proof stock base combination " that use hydrolecithin W/O/W bilayer micron ball cladding prepares through secondary again, the cosmetic composition obtained, including glyceryl stearate 100 stearate, cetearyl alcohol cetearyl glucoside, cetearyl alcohol, Adeps Bovis seu Bubali resin, candlenut oil, iso-octyl palmitate, polysiloxanes and other suitable excipients.Achieve the effect having reached the spf value more than 35 in the case of component of sun total mass fraction is less than or equal to 12%.

Description

A kind of cosmetic composition and preparation method thereof
Technical field
The present invention relates to use " the sun-proof stock base combination " of lecithin W/O/W bilayer micron ball cladding to join through secondary again System, the cosmetic composition obtained.
Background technology
The sun care preparations developing high SPF (sun protection factor) (spf value) is always the hot issue of cosmetics worker research, especially It is to add a small amount of sunscreen to make the high sun-proof performance of cosmetics acquisition be always direction and the difficult problem that researcher is made great efforts, tradition On, it is all to obtain high sun-proof performance (indicating with high spf value) by the substantial amounts of sunscreen of interpolation, this method exists all Many problems, the dosage form of cosmetics, stability, use skinfeel are difficult to control by the membership that adds of such as a large amount of sunscreen；Some chemistry Sunscreen also exists relatively Thief zone absorbtivity in the case of high-load, can be greatly improved the risk of cutaneous safety, chemistry anti- Shine degradable, the increase product cost of agent instability etc.；Also some opaque sunscreen (such as titanium dioxide) addition is high, it is also possible to Result in blockage pore, and easily generation " blackhead ", " acne " skin problem.Relate to reducing sunscreen addition at present and realize height The patent of the sun care preparations of spf value also can be found.Some is to be realized by sunscreen and the combination of polymer, assembling effect , such as patent CN1316239A, CN101371816A, US7264795, US5487886, US5145669, US4663157, US 6409998, US 6312672, US0148647A1, some is the combination by different sunscreen or sunscreen and other little molecules Compound combination acts synergistically realize, as patent CN1339960A, CN1425366A, CN101460135A, US7014842, CN 102387781 A、CN 103002865 A、CN 102946848 A、CN 103221026 A、CN 103501759 A、CN 104010621 A, WO2014023481A2, WO2014102050A2, some be by prepare that new preparation system realizes as Patent CN1273525A, some be by bonding agent cladding realize as patent US5733531, CN102076382A, CN102076320A, patent CN 102596150 A utilize agar microgel to improve sun-proof performance and the use skinfeel of cosmetics. Sum up these patents it is seen that: be mostly the collocation from sunscreen raw material go out to send raising sun-proof performance, seldom have consideration In the whole compositions of cosmetics, other components (base material) impact on SPF (sun protection factor), secondly, from the point of view of current patent, want To the SPF (sun protection factor) SPF (sun protection factor) (spf value) more than 30, the sunscreen content mass fraction of interpolation at least to account for whole cosmetics More than the 12% of compositions (formula) content (100%).
Summary of the invention
The present invention provides a kind of interpolation to be coated with one or more sunscreen shapes by hydrolecithin W/O/W bilayer micron ball " the sun-proof stock base combination " become, then secondary generation cosmetic composition, can be opened in skin surface by uniform spreading, maximize " fishnet effect " phenomenon or sunscreen part that minimizing sunscreen products the most easily occurs when covering and being coated with and use are absorbed by the skin phenomenon, thus Being greatly improved the cosmetic composition of SPF (sun protection factor) (spf value), the cosmetic composition provided is adding chemical sunscreen Under conditions of agent composition total mass fraction is less than 12%, SPF (sun protection factor) (spf value) >=35, it might even be possible to far surpass 45, provided is anti- Shine cosmetic composition and there is good storage stability, superior waterproof sweat resistance energy, preferably use skinfeel, use rear excellence Use sense, the outward appearance of bright and clean exquisiteness.
The dosage form that the cosmetic composition that the present invention provides prepares is emulsion or cream, is a kind of oil-in-water in particular Bao Shui (W/O/W) ultra light sun block lotion or cream.
Cosmetic composition/formula that the present invention provides contains the sun-proof of hydrolecithin W/O/W bilayer micron ball parcel Agent combination is combined as sun-proof stock base, and this " sun-proof stock base combination " quality accounting in formula is 0.01%- 15.0%, it is preferred that for 2.0%-12.0%.
For cream emulsus or wax under " sun-proof stock base combination " room temperature that the cosmetic composition that the present invention provides is applied Sense solid.
In " sun-proof stock base combination " that the cosmetic composition that the present invention provides is applied, the quality of hydrolecithin Mark is 5%-30%, preferably 8%-20%.
The cosmetic composition that the present invention provides, in " sun-proof stock base combination ", the sunscreen contained can include first The different monooctyl ester of epoxide cinnamic acid, BP-3 and butylmethoxydibenzoylmethane, such as p-methoxycinnamic acid are different The mass fraction accounting of monooctyl ester can be 60%-90%, is excellent with 70%-90%；BP-3 mass fraction accounting permissible For 5%-40%, being excellent with 15%-25%, the mass fraction of butylmethoxydibenzoylmethane is 0.1% ~ 5%, it is ensured that each group Proportion by subtraction example summation is 100%.
Emulsifying agent used by the cosmetic composition that the present invention provides is preferably composite emulsifier, and one of which emulsifying agent is such as Being Gan Youyingzhisuanzhi &PEG-100 stearate, trade name Cithrol GMS A/S(manufacturer is Britain Croda chemistry Product company), the quality accounting in formula is 0.05%-3.0%, is advisable with 0.5%-2.0%, is excellent with 1.0%-1.8%.Another kind of Emulsifying agent e.g. cetearyl alcohol & cetearyl glucoside, trade name Montanov 68(manufacturer is France SEPPIC chemical company), the quality accounting in formula is 0.05%-3.0%, is advisable with 0.2%-2.0%, with 0.6%-1.2% For excellent.
Cosmetic composition/formula that the present invention provides contains cetearyl alcohol, and its quality accounting in formula is 0.01%-2.0%, is advisable with 0.2%-1.5%, is excellent with 0.5%-1.2%, its role is to skin moistening, moisturizing thickening, increases formula Stability.
Cosmetic composition/formula that the present invention provides contains Adeps Bovis seu Bubali resin, and its quality accounting in formula is 0.01%-6.0%, is advisable with 0.8%-4.0%, its role is to skin moistening moisturizing, the carrier as sunscreen, makes sunscreen rest on Skin epidermis layer, it has absorption maximum to the ultraviolet of 275nm simultaneously, as sunscreen auxiliary absorbent, improves formulation product Sun-proof ability.
Cosmetic composition/formula that the present invention provides contains candlenut oil, and its quality accounting in formula is 0.01%-5.0%, is advisable with 0.5%-3.0%.Effect is skin moistening moisturizing, increases the permeability of formulation product, makes sunscreen fix At epithelial layer, improve the sun-proof ability of formulation product.
Cosmetic composition/formula that the present invention provides contains iso-octyl palmitate, and the quality accounting in formula is 0.01%-15.0%, is advisable with 2.0%-10.0%, its role is to skin moistening moisturizing, increase the spreadability of formulation product, permeability, Screening characteristics, simultaneously as the carrier of sunscreen, contributes to that sunscreen is dispersed on skin, make sunscreen be fixed on epithelium Layer, improves the sun-proof ability of formulation product.
The present invention provide cosmetic composition/formula contain low viscosity polydimethylsiloxane or (with) the poly-first of low viscosity Base phenyl siloxane or (with) ring five polysiloxanes, its quality accounting in formula is 0.01%-20%, is advisable with 5%-15%. Effect is skin moistening moisturizing, forms the thin film that fastness is strong as sunscreen carrier on skin, increases the water resistant of formulation product Property, preferably improve the SPF (sun protection factor) of formulation product.
Cosmetic composition/formula that the present invention provides, further contains antioxidant, antioxidant preferred vitamin A cetylate, sodium L-ascorbate-2-phosphate, vitamin e acetate, the quality accounting in formula is 0.01%-1.5%, with 0.1%-1.0% is advisable, and effect is to increase formulation product oxidation resistance.
Cosmetic composition/formula that the present invention provides contains acrylic acid (ester) class/t-octylacrylamido, business The name of an article is Dermacryl-79, and the quality accounting in formula is 0.01%-5.0%, is advisable with 1.0%-5.0%.Effect is to increase Skin feel after big formulation product using film property and improving the use of formulation product on skin, increases formula simultaneously and produces The waterproof anti-antiperspirant performance of keeping humidity of product, increases the sun-proof performance of formulation product.
Cosmetic composition/formula that the present invention provides contains chain alkyl amine, and effect is to neutralize Dermacryl-79, Playing Dermacryl-79 waterproof sweat resistance energy in the product to greatest extent, chain alkyl amine can be Semen Myristicae amine, palm fibre Palmitic acid amine, stearylamine etc., the quality accounting in formula is as the criterion with the degree of neutralization neutralizing the 80%-100% of Dermacryl-79.Typically Mass ratio in formula is 0.01%-3.5%, is advisable with 0.5%-3.0%.
The present invention provide cosmetic composition/formula further preferred containing chelating agen, chelating agen typically uses EDTA- Disodium, the ratio in formula is 0.01%-0.08%, is advisable with 0.04%, in order to chelate the metal ion in water, is that formula produces Product are more stable.
Cosmetic composition/formula that the present invention provides contains acrylic compounds water-soluble polymer, acrylic acid water-soluble poly Compound can be acrylic acid/C10-C30 alkylmethacrylate copolymer, acrylates/C10-C30 alkyl acrylate altogether One or more mixing of polymers emulsifying agent, acrylate/polyoxyethylene stearyl alcohol ether metacrylic acid ester, effect is to increase The film property of formulation product, moisture retention, thickening suspension stability, this base polymer commercially available prod has a lot, such as Carbopol 934、Carbopol 940 Polymer、Carbopol 941、Dexon P940、Carbopol Ultrez 10 Polymer、 Carbopol Ultrez 20 Polymer 、Carbopol Ultrez 21 Polymer、 Carbopol ETD 2020 Polymer, with Carbopol 940 Polymer, Carbopol 941, Carbopol Ultrez 20 in these commodity Polymer, Carbopol Ultrez 21 Polymer, Carbopol ETD 2020 Polymer is the most commonly used, and selected third Olefin(e) acid polymer quality accounting in formula is 0.01%-1%, is advisable with 0.05%-0.5%.
The present invention provide cosmetic composition/formula further preferably comprise polyhydric alcohol, polyhydric alcohol can be glycerol, Propylene glycol, butanediol, pentanediol etc., effect is to improve performance of keeping humidity and the comfort of formulation product, in formula Quality accounting be 0.01%-10.0%, be advisable with 1.0%-5.0%.
Cosmetic composition/formula that the present invention provides contains nertralizer, in order to neutralize acrylic compounds water solublity in formula Polymer, it is achieved acrylic polymer moisturizing film forming thickening suspension emulsifiability in formulation product, regulates formula simultaneously The pH value of product between 5.0-7.0, selected nertralizer can be sodium hydroxide, potassium hydroxide, ammonium hydroxide, triethanolamine, AMP etc., the quality accounting in formula is determined by the amount of acrylic polymer in formula and selected nertralizer kind, So that the pH value of formulation product is adjusted to the 5.5-6.5 standard as addition during specific experiment, typically constitute from prescription quality ratio 0.01%-0.8%, is advisable with 0.01%-0.3%.
Cosmetic composition/formula that the present invention provides preferably contains sodium acrylate/sodium acryloyldimethyl taurate Copolymer & 2-Methylpentadecane & Polyoxyethylene Sorbitan Monooleate emulsifying agent, the trade name Simulgel EG(manufacturer of this emulsifying agent is method State's SEPPIC chemical company).Effect is strengthen the stability of formulation product, aesthetic finish and use skinfeel affinity. Quality accounting in formula is 0.01%-1.0%, is advisable with 0.2%-0.8%, is optimal with 0.3%-0.6%.
Cosmetic composition/formula that the present invention provides preferably contains preservative, and selected preservative can be benzene oxygen second Alcohol, 2-bromo-2-nitro-1,3-glycol, parabens, Methylisothiazolinone, methylchloroisothiazandnone, imidazolidinyl One or more in urea, chlorphenesin, the quality accounting in formula is generally 0.01%-2.0%, with 0.05%-0.8% is Preferably.
Can also contain other sunscreen in " sun-proof stock base combination " that the present invention provides, other sunscreen can be One or more in salicylic acid esters, methane Derivatives class benzophenone and derivatives class, o-aminobenzoa class etc., its The addition of his sunscreen can make the SPF (sun protection factor) of whole formulation product to be greatly improved, and other sunscreen component is " sun-proof former Material substrate combination " in addition accounting be generally 5%-30%, it is ensured that each component total amount is 100%.
Cosmetic composition/formula that the present invention provides can also contain other both effectiveness active ingredient, as whitening becomes Divide arbutin derivant, kojic acid derivative, Radix Glycyrrhizae extract, silk-extract, green tea extract etc., aging ingredient SOD, paddy The sweet peptide of Guang, collagen protein etc., anti-acne composition fruit acid, Flos Chrysanthemi extract, Radix Sophorae Flavescentis extract, chamomile extract etc., add each Kind of functional activity compound component can make formulation product realize many effects, these other both effectiveness active ingredient addition one As be 0.01%-5.0%, be advisable with 0.05%-2.0%.
Cosmetic composition/formula that this patent provides can be added as needed on suitable perfume ingredient, gives formula The odor type that product is different.The addition of essence is generally 0.01%-0.15%.
Advantages of the present invention
What the present invention provided is added with the cosmetic of the sun-proof stock base combination with hydrolecithin W/O/W bilayer micron ball cladding Product compositions/formula, thus formula prepare emulsion or cream, chemical sun total raw material composition only need to add less than 12%, with regard to energy Obtain the sun care preparations that SPF (sun protection factor) (spf value) is much higher than 35, and the sun care preparations of the present invention has the anti-of excellence Water sweat resistance energy and superior use sense, and production operation is simple, easily realizes.
Detailed description of the invention
Cosmetic composition (formula) preparation method of the present invention comprises the steps:
According to the present invention a kind of formula, successively by Gan Youyingzhisuanzhi &PEG-100 stearate, cetearyl alcohol & spermaceti Stearyl glucoside, cetearyl alcohol, shea butter, candlenut oil, iso-octyl palmitate, non-volatile low viscosity polysiloxanes Polymer, oil-soluble inhibitor, chain alkyl amine, other oil-soluble chemical sun, parabens preservative add oil Pot is heated to 80-85 DEG C mutually, is allowed to be completely dissolved, is then the most slowly sprinkled into by Dermacryl-79, and keeps temperature With continuously stirred 30 minutes, prepare oil phase；
Slowly being sprinkled in water by acrylic polymer, completely, addition polyhydric alcohol, chelating agen are heated to 80 ~ 85 to homogenizing to dispersion DEG C, prepare aqueous phase；
Being joined by oil-phase component in aqueous phase, emulsifying is complete, adds " sun-proof stock base combination ", continues stirring insulation A period of time, it is cooled to 55-60 DEG C and adds Simulgel EG, nertralizer and volatile siloxane polymer, stir, Continue cool to 40-50 DEG C and add essence, preservative and other both effectiveness compositions.Stir the most prepared.
The preparation method of described sun-proof stock base combination:
By the quality of hydrolecithin, the different monooctyl ester of methoxy cinnamic acid and BP-3, butyl methoxy dibenzoyl base Methane premix (or in salicylic acid esters, methane Derivatives class benzophenone and derivatives class, o-aminobenzoa class etc. The different monooctyl ester of one or more hydrolecithins, methoxy cinnamic acid and BP-3, butyl methoxy dibenzoyl Ji Jia Alkane premixes), after slowly stirring, add in high pressure homogenizer, first with high pressure homogenizer, under the high pressure of 125MPa, homogenizing is also Online high shear homogenizing about 60min, then stop 20min, it is set to altogether in a cycle, in 2 cycles of experience this cycle, obtain pre- Mixed sunscreen diameter of particle controls the blended mixture serosity in 1 ± 0.3 μm.First mixture serosity is carried out again by complex coacervation Micro encapsulation cladding, then this microcapsule carries out solidifying and separating, then uses spray drying method to microcapsule of gained Carry out second time cladding to process, finally give the microcapsule of double-coating, thus realize wrapping up chemical sun mixture serosity In the double-deck microsphere of W/O/W.
Embodiment one
Precise Gan Youyingzhisuanzhi &PEG-100 stearate (trade name Cithrol GMS A/S) 1.2g, cetearyl alcohol Alcohol & cetearyl glucoside (trade name Montanov 68) 0.8g, cetearyl alcohol 1.0g, shea butter 2.0g, Semen Aleuritis Moluccanae Oil 1.0g, iso-octyl palmitate 5.0g, polydimethylsiloxane (trade name SF1000N, 350CST) 6.0g, vitamin E acetic acid Ester 0.5g, methyl hydroxybenzoate 0.1g, propylparaben 0.05g, cetylamine 1.0g, be mixed and heated to 85 DEG C and be allowed to dissolve completely, Then Dermacryl-79 2.0g is the most slowly sprinkled in oil phase, holding temperature continuously stirred 30 minutes, prepares oil Phase；Weighing deionized water 67.0g, weigh Carbopol941 polymer 0.1g, spread in deionized water, homogenizing is to having disperseed Entirely, add EDTA-disodium 0.02g, glycerol 5.0g, stir and be heated to 85 DEG C, prepare aqueous phase；Oil phase is joined aqueous phase In, emulsifying 3min, add sun-proof stock base combination 8.0g, insulated and stirred 10min, be cooled to 60 DEG C and add Simulgel EG 0.3g, triethanolamine 0.075g, Cyclomethicone 2.0g, stir, and continues cool to 45 DEG C and adds rose Essence 0.0005g, Preservative Kathon CG(Methylchloroisothiazolinone/Methylisothiazolinone combination) 0.12g, stir and i.e. prepare this ultra light sun block lotion.
Embodiment two
Precise Gan Youyingzhisuanzhi &PEG-100 stearate (trade name Cithrol GMS A/S) 1.2g, cetearyl alcohol Alcohol & cetearyl glucoside (trade name Montanov 68) 1.0g, cetearyl alcohol 0.8g, shea butter 1.5g, Semen Aleuritis Moluccanae Oil 2.0g, iso-octyl palmitate 3.0g, polydimethylsiloxane (trade name SF1000N, 5CST) 8.0g, vitamin e acetate 0.2g, methyl hydroxybenzoate 0.05g, propylparaben 0.02g, 18-amine. 1.5g, be mixed and heated to 85 DEG C and be allowed to dissolve completely, so After Dermacryl-79 3.0g is the most slowly sprinkled in oil phase, keep temperature continuously stirred 30 minutes, prepare oil Phase；Weigh deionized water 71.0g, weigh Carbopol Ultrez 20 Polymer 0.2g, spread in deionized water, homogenizing To dispersion completely, add EDTA-disodium 0.02g, propylene glycol 3.0g, stir and be heated to 85 DEG C, prepare aqueous phase；Oil phase is added Enter in aqueous phase, emulsifying 3min, add sun-proof stock base combination 9.0g, insulated and stirred 10min, be cooled to 55 DEG C of additions Simulgel EG 0.2g, sodium hydroxide 0.040g, stir, and continues cool to 45 DEG C and adds Arctostaphylos ura-ursi extract 0.02g, sweet Grass extract 0.02g, jasmin essence 0.0005g, preservative germall 0.05g, stir and i.e. prepare this ultra light sun block lotion.
Embodiment three
Precise Gan Youyingzhisuanzhi &PEG-100 stearate (trade name Cithrol GMS A/S) 1.3g, cetearyl alcohol Alcohol & cetearyl glucoside (trade name Montanov 68) 0.9g, cetearyl alcohol 1.2g, shea butter 1.2g, Semen Aleuritis Moluccanae Oil 1.5g, iso-octyl palmitate 4.0g, polydimethylsiloxane (trade name DOW CORNING 200 FLUID, 50 CST) 7.0g, vitamin A palmitate 0.3g, Antisolaire 5.0g, methyl hydroxybenzoate 0.15g, propylparaben 0.10g, tetradecy lamine 1.8g, be mixed and heated to 85 DEG C and be allowed to dissolve completely, then by the slowest for Dermacryl-79 4.0g Slowly it is sprinkled in oil phase, holding temperature continuously stirred 30 minutes, prepares oil phase；Weigh deionized water 63.0g, weigh Carbopol Ultrez 21 Polymer 0.05g, spreads in deionized water, and homogenizing is complete to dispersion, addition EDTA-disodium 0.02g, and 1,3- Butanediol 5.0g, stirs and is heated to 85 DEG C, prepares aqueous phase；Oil phase is joined in aqueous phase, emulsifying 2min, add anti- Shine stock base combination 4.0g, insulated and stirred 10min, be cooled to 60 DEG C and add Simulgel EG 0.4g, potassium hydroxide 0.02g, stirs, and continues cool to 45 DEG C and adds Flos Chrysanthemi extract 0.02g, Radix Sophorae Flavescentis extract 0.02g, osmanthus flower fragrance 0.0003g, preservative Bronopol 0.07g, stir and i.e. prepare this ultra light sun block lotion.
Hereinafter, for physical and chemical index, the stability test of embodiment one, two, three ultra light sun block lotion.
Stability test:
Test when embodiment prepares emulsion T=0 and 25 DEG C place two months after T=2 month outward appearance of (25 DEG C), pH value and viscous Degree, outward appearance, pH value and the viscosity of T=2 month (45 DEG C) after also tested under the conditions of 45 DEG C two months simultaneously.Viscosity test is Test with DV-II Pro digital display viscometer (BROOKFIELD, the U.S.), selection 25 DEG C, 2# rotor, the test of 12rpm during test Condition, result sees below:
Table 1: stability test
Outward appearance PH Viscosity (cps)
Embodiment one T=0 White uniformity smooth emulsion 5.83 6860
Embodiment one T=2 month (25 DEG C) White uniformity smooth emulsion 5.85 6950
Embodiment one T=2 month (45 DEG C) White uniformity smooth emulsion 5.81 6780
Embodiment two T=0 White uniformity smooth emulsion 6.00 7535
Embodiment two, T=2 month (25 DEG C) White uniformity smooth emulsion 6.02 7669
Embodiment two T=2 month (45 DEG C) White uniformity smooth emulsion 6.05 7512
Embodiment three T=0 White uniformity smooth emulsion 6.23 7229
Embodiment three T=2 month (25 DEG C) White uniformity smooth emulsion 6.21 7350
Embodiment three T=2 month (45 DEG C) White uniformity smooth emulsion 6.19 7187
Stability test result shows that embodiment one, two, three formulation product all has preferable stability.
It is below the spf value test of embodiment one, two, three ultra light sun block lotion:
Method of testing is according to " cosmetics health specification " Ministry of Health of the People's Republic of China in January, 2007 Part V four (1) sun care preparations SPF (sun protection factor) (spf value) assay method (page 283) is tested, experimenter totally 20 people, wherein man 5 People, female 15 people, the age 18-45 year between, measurement result coincidence detection method requirement, each embodiment ultra light sun block lotion spf value tie Fruit sees below:
Table 2:SPF value is tested
Embodiment one spf value Embodiment two spf value Embodiment three spf value
42 35 38
Spf value test result shows that embodiment 1,2,3 formulation product all has higher SPF (sun protection factor).
It it is below the water resistance test of embodiment one, two, three ultra light sun block lotion
Method of testing is according to " cosmetics health specification " Ministry of Health of the People's Republic of China in January, 2007 Part V four (2) sun care preparations water resistance assay method (page 287) is tested, and experimenter tests same crowd for SPF (sun protection factor), The spf value measured after water-resistance test in 80 minutes sees below:
Table 3: water resistance is tested
Embodiment one spf value Embodiment two spf value Embodiment three spf value
32 29 31
After water-resistance test in 80 minutes, SPF is followed successively by embodiment one 23.8%, embodiment 2 17.1%, embodiment three to decrement 18.4%。
Water resistance test result shows that embodiment one, two, three formulation product all has great water proofing property.
It is below the use sensing examination of embodiment one, two, three ultra light sun block lotion:
Method of testing is for being carried out actually used test by panel and being evaluated, totally five panels, each the least Group is made up of 5 professional teachers, every group score take its group in proprietary average, evaluation criterion sees below:
Table 4: use sensing examination
Project Difference Evaluation score (5 grades) Good
Spreadability Weight -2 ,-1,0,1,2 Gently
Dry sensation Have -2 ,-1,0,1,2 Nothing
Tunicle sense Have -2 ,-1,0,1,2 Nothing
Soft and smooth sense Nothing -2 ,-1,0,1,2 Have
Greasy feeling Nothing -2 ,-1,0,1,2 Have
Comprehensive hobby Detest -2 ,-1,0,1,2 Like
The following is embodiment one, embodiment two, the evaluation result of embodiment three ultra light sun block lotion
Table 5: embodiment one evaluation result
Project Professional group A Professional group B Professional group C Professional group D Professional group E Averagely
Spreadability 2 1 1 1 2 1.4
Dry sensation 2 2 1 2 1 1.6
Tunicle sense 1 1 0 1 0 0.6
Soft and smooth sense 2 0 2 1 1 1.2
Greasy feeling 1 1 1 1 2 1.2
Comprehensive hobby 1 2 1 2 1 1.4
Table 6: embodiment two evaluation result
Project Professional group A Professional group B Professional group C Professional group D Professional group E Averagely
Spreadability 1 2 1 2 1 1.4
Dry sensation 1 1 2 2 1 1.4
Tunicle sense 0 1 1 1 1 0.8
Soft and smooth sense 0 2 2 1 1 1.2
Greasy feeling 2 1 2 1 2 1.6
Comprehensive hobby 1 2 2 1 1 1.4
Table 7: embodiment three evaluation result
Project Professional group A Professional group B Professional group C Professional group D Professional group E Averagely
Spreadability 2 1 1 2 1 1.4
Dry sensation 1 1 1 2 1 1.2
Tunicle sense 1 1 1 0 1 0.8
Soft and smooth sense 1 1 2 1 1 1.2
Greasy feeling 2 2 2 1 2 1.8
Comprehensive hobby 2 1 2 1 1 1.4
Sensing bright embodiment one, two, three formulation product of taking temperature is used all to have preferable spreadability, moisture retention, skin affinity, clearly Non-greasy, compares and is liked by user.
Embodiment described above is only to be described the preferred embodiment of the present invention, the not model to the present invention Enclose and be defined, on the premise of designing spirit without departing from the present invention, this area ordinary skill technical staff skill to the present invention Various deformation that art scheme is made and improvement, within all should falling into the protection domain that claims of the present invention determines.

Claims (10)

1. a cosmetic composition, comprises the various compositions of following mass percent:
Gan Youyingzhisuanzhi &PEG-100 stearate 0.05%-3.0%；
Cetearyl alcohol & cetearyl glucoside 0.05%-3.0%；
Cetearyl alcohol 0.01%-2.0%；
Adeps Bovis seu Bubali resin 0.01%-6.0%；
Candlenut oil 0.01%-5.0%；
Iso-octyl palmitate 0.01%-15.0%；
Polydimethylsiloxane is or/and PSI is or/and ring five polysiloxanes 0.01%-20%；
Acrylate/octylacrylamido 0.01%-5.0%；
Chain alkyl amine 0.01%-3.5%；
Acrylic compounds water-soluble polymer 0.01%-1%；
Nertralizer 0.01%-0.8%；
The sun-proof stock base combination 2.0%-10.0% of hydrolecithin W/O/W bilayer micron ball parcel；
Other adjuvant；
Described nertralizer is in order to neutralize acrylic compounds water-soluble polymer, it is achieved acrylic polymer moisturizing in the composition Film forming thickening suspension emulsifiability, regulates the pH value of compositions between 5.0-7.0 simultaneously.
2. a cosmetic composition, comprises the various compositions of following mass percent:
Gan Youyingzhisuanzhi &PEG-100 stearate 1.0%-1.8%；
Cetearyl alcohol & cetearyl glucoside 0.6%-1.2%；
Cetearyl alcohol 0.5%-1.2%；
Adeps Bovis seu Bubali resin 0.8%-4.0%；
Candlenut oil 0.5%-3.0%；
Iso-octyl palmitate 2.0%-10.0%；
Polydimethylsiloxane is or/and PSI is or/and ring five polysiloxanes 5.0%-15.0%；
Acrylate/octylacrylamido 1.0%-5.0%；
Chain alkyl amine 0.5%-3.0%；
Acrylic compounds water-soluble polymer 0.05%-0.5%；
Nertralizer 1.0%-5.0%；
The sun-proof stock base combination 2.0%-10% of hydrolecithin W/O/W bilayer micron ball parcel；
Other adjuvant；
Described nertralizer is in order to neutralize acrylic compounds water-soluble polymer, it is achieved acrylic polymer moisturizing in the composition Film forming thickening suspension emulsifiability, regulates the pH value of compositions between 5.0-7.0 simultaneously.
3. according to the cosmetic composition of claim 1 or 2, other adjuvant include antioxidant, chelating agen, polyhydric alcohol, Emulsifying agent, preservative；Described antioxidant mass fraction is 0.01%-1.5%, and chelating agen mass fraction is 0.01%-0.08%, many Unit's alcohol mass fraction is 0.01%-10.0%, and emulsifying agent mass fraction is 0.01%-1.0%, and preservative mass fraction is 0.01%- 2.0%。
4. according to the cosmetic composition of claim 1 or 2, sun-proof stock base combination in containing 60%-90% to first The different monooctyl ester of epoxide cinnamic acid and/or the BP-3 of 5%-40%, the hydrolecithin of 5%-30% and butylmethoxy hexichol Formoxyl methane 0.1% ~ 5%, amounts to 100%.
5., according to the cosmetic composition of claim 1 or 2, the combination of sun-proof stock base includes salicylic acid esters, methane Derivatives class benzophenone and derivatives class thereof, o-aminobenzoa apoplexy due to endogenous wind one or more, chain alkyl amine is selected from: lima bean Cool amine, palmitamide, stearylamine.
Cosmetic composition the most according to claim 5, sun-proof stock base combination in containing 70%-90% to methoxyl group The different monooctyl ester of cinnamic acid and/or the BP-3 of 15%-25%, the hydrolecithin of 8%-20% and butyl methoxy dibenzoyl Methylmethane 0.1% ~ 5%, total amount 100%.
Cosmetic composition the most according to claim 4, it is characterised in that by different for methoxy cinnamic acid monooctyl ester, hexichol first Ketone-3 and, hydrolecithin, premix, after slowly stirring, add in high pressure homogenizer, first exist with high pressure homogenizer Homogenizing online high shear homogenizing about 60min under the high pressure of 125MPa, then stop 20min, it is set to a cycle, this week altogether In 2 cycles of experience phase, obtain premixing sunscreen diameter of particle and control the blended mixture serosity in 1 ± 0.3 μm, then pass through complex coacervation Method first carries out micro encapsulation cladding for the first time to mixture serosity, and then this microcapsule carries out solidifying and separating, then uses spray dried Dry method carries out second time cladding and processes microcapsule of gained, finally gives the microcapsule of double-coating, the most sun-proof raw material base The end, combines.
Cosmetic composition the most according to claim 3, wherein antioxidant is selected from: vitamin A palmitate, vitamin C cetylate, vitamin e acetate, wherein polyhydric alcohol is selected from: glycerol, propylene glycol, butanediol, pentanediol；Preservative is selected from: Phenoxyethanol, 2-bromo-2-nitro-1,3-glycol, parabens, Methylisothiazolinone, methylchloroisothiazandnone, imidazoles One or more in ureine, chlorphenesin.
9., according to the cosmetic composition of claim 1 or 2, it further comprises other efficacy active components, described other Efficacy active component selected from arbutin derivant, kojic acid derivative, Radix Glycyrrhizae extract, silk-extract, green tea extract, SOD, One or more in glutathion, collagen protein, fruit acid, Flos Chrysanthemi extract, Radix Sophorae Flavescentis extract, chamomile extract.
10. a preparation method for cosmetic composition, comprises the steps:
According to each component ratio described in any one of claim 1-9, by Gan Youyingzhisuanzhi &PEG-100 stearate, spermaceti Stearyl alcohol & cetearyl glucoside, cetearyl alcohol, shea butter, candlenut oil, iso-octyl palmitate, polysiloxanes are poly- Compound, antioxidant, chain alkyl amine, sunscreen, preservative add oil phase pot and are heated to 80-85 DEG C, are allowed to be completely dissolved, so After acrylate/octylacrylamido is the most slowly sprinkled into, and keep temperature and continuously stirred 30 minutes, system Obtain oil phase；
Slowly being sprinkled in water by acrylic polymer, completely, addition polyhydric alcohol, chelating agen are heated to 80 ~ 85 to homogenizing to dispersion DEG C, prepare aqueous phase；
Being joined by oil-phase component in aqueous phase, emulsifying is complete, adds the combination of sun-proof stock base, continues stirring insulation one The section time, it is cooled to 55-60 DEG C and adds Simulgel EG, nertralizer and siloxane polymer, stir, continue cooling Add essence, preservative and other both effectiveness compositions to 40-50 DEG C, stir.
CN201610777398.9A 2016-08-31 2016-08-31 A kind of cosmetic composition and preparation method thereof Pending CN106176478A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107638307A (en) * 2017-09-19 2018-01-30 澳宝化妆品（惠州）有限公司 A kind of sunscreen spray composition
CN107638343A (en) * 2017-09-19 2018-01-30 澳宝化妆品（惠州）有限公司 A kind of sunscreen spray composition of the component of antiallergic containing plant
CN107823004A (en) * 2017-12-12 2018-03-23 云南百叶集生物科技有限公司 Plant composition with anti-sunlight function and its application in sunscreen product
CN108049175A (en) * 2017-11-09 2018-05-18 安徽美德发艺有限责任公司 A kind of sun-screening agent for patch-type seamless sending and receiving
CN110799169A (en) * 2017-08-02 2020-02-14 吉欧化工有限公司 Cosmetic preparation
CN115350099A (en) * 2022-08-26 2022-11-18 广州栋方生物科技股份有限公司 Emulsification method and application of oil-in-water type sunscreen composition

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CN1798538A (en) * 2003-06-03 2006-07-05 默克专利股份有限公司 Photostable organic sunscreen composition
CN101309746A (en) * 2005-08-22 2008-11-19 塔格拉生物科技有限公司 Method for production of single- and multi-layer microcapsules

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Publication number Priority date Publication date Assignee Title
CN1798538A (en) * 2003-06-03 2006-07-05 默克专利股份有限公司 Photostable organic sunscreen composition
CN101309746A (en) * 2005-08-22 2008-11-19 塔格拉生物科技有限公司 Method for production of single- and multi-layer microcapsules

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110799169A (en) * 2017-08-02 2020-02-14 吉欧化工有限公司 Cosmetic preparation
CN107638307A (en) * 2017-09-19 2018-01-30 澳宝化妆品（惠州）有限公司 A kind of sunscreen spray composition
CN107638343A (en) * 2017-09-19 2018-01-30 澳宝化妆品（惠州）有限公司 A kind of sunscreen spray composition of the component of antiallergic containing plant
CN107638343B (en) * 2017-09-19 2019-11-15 澳宝化妆品（惠州）有限公司 A kind of sunscreen spray composition of the component of antiallergic containing plant
CN108049175A (en) * 2017-11-09 2018-05-18 安徽美德发艺有限责任公司 A kind of sun-screening agent for patch-type seamless sending and receiving
CN107823004A (en) * 2017-12-12 2018-03-23 云南百叶集生物科技有限公司 Plant composition with anti-sunlight function and its application in sunscreen product
CN115350099A (en) * 2022-08-26 2022-11-18 广州栋方生物科技股份有限公司 Emulsification method and application of oil-in-water type sunscreen composition
CN115350099B (en) * 2022-08-26 2023-12-29 广州栋方生物科技股份有限公司 Emulsification method of oil-in-oil type sun-screening composition and application thereof

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Application publication date: 20161207