CN106176377B - A kind of sun-proof synergistic composition of plant origin and preparation method thereof - Google Patents
A kind of sun-proof synergistic composition of plant origin and preparation method thereof Download PDFInfo
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- CN106176377B CN106176377B CN201610642408.8A CN201610642408A CN106176377B CN 106176377 B CN106176377 B CN 106176377B CN 201610642408 A CN201610642408 A CN 201610642408A CN 106176377 B CN106176377 B CN 106176377B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/737—Galactomannans, e.g. guar; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/738—Cyclodextrins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
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Abstract
The present invention relates to sun-proof synergistic compositions of a kind of plant origin and preparation method thereof, it is characterised in that: is made of hydrolysis rice bran extract, cistus incanus flower/leaf/stem extraction, marigold flower extract, navel shape seaweed extract, edelweiss extract, gamma-cyclodextrin and hydroxypropyl guar gum according to mass ratio 3-5:1-3:1-3:3-5:3-5:15-20:5-10.The present invention can play protective action near infrared band and visible blue wavelengths, and the sun-proof result of existing sun-screening agent can be enhanced.
Description
Technical field
The present invention relates to cosmetic technical field, in particular to the sun-proof synergistic composition of a kind of plant origin and its preparation
Method.
Background technique
Ultraviolet light can be divided into UVC(short wave ultraviolet, 200nm-290nm by its wavelength), UVB(ultraviolet B radiation, 290nm-
320nm) and UVA(long wave ultraviolet, 320nm-400nm).The UVC that ground is reached after ozone layer is very faint, and UVB only has part
It is absorbed by ozone layer, and UVA is not absorbed completely.Therefore, the ultraviolet light on ground is mainly by 10% UVB and 90% UVA group
At.UVB is strong to skin ability to function, will appear oedema, blister, erythema, decortication, skin aging after irradiation.UVA penetration power is strong,
There is accumulation in reachable dermis of skin depths to skin effect, permanent irradiation can cause skin brown, collagenous fibres fracture,
Flexibility decrease, wrinkle generate, and lead to cutaneum carcinoma.In addition, with climate warming, depletion of the ozone layer, it is seen that blue light (400-
500 nm) and near infrared ray IRA (700-1000nm) in daily life expose chance it is more and more, lead to matrix metalloprotease
The synthesis of enzyme MMP increases, and promotes the degradation of collagen, accelerates skin aging process.
In order to reach ideal sun-proof result, it should at the same include can reduce injury of the near infrared ray to skin at
Point, and the ingredient of protection visible blue wavelengths, then the ingredient of cooperation protection UVB and UVA wave band, could constitute one in this way
More complete wide spectrum skin care protective net., it is specified that there is 27 in China " cosmetics safety technical specification " (version in 2015)
Mutatis mutandis sun-screening agent, wherein Orangic sunscreen has 25 kinds, and 2 kinds of inorganic sunscreen, but these are all artificial synthesized chemical sunscreen knots
Structure, and these ingredients are usually only capable of the ultraviolet light of protection UVB wave band and UVA wave band, are not related to near infrared band and visible indigo plant
The protection of optical band.When needing more broadband protection, especially near infrared band and blue wave band are protected, only national regulation
27 kinds of sun-screening agents be inadequate.
Summary of the invention
The technical problem to be solved by the present invention is to providing a kind of can play protection near infrared band and visible blue wavelengths
Effect, safe, plant origin sun-proof synergistic composition and preparation method thereof.
To solve above-mentioned technical problem: the present invention provides a kind of following solution: sun-proof synergistic combination of plant origin
Object, it is characterised in that: purple by hydrolysis rice bran extract, cistus incanus flower/leaf/stem extraction, marigold flower extract, navel shape
Dish extract, edelweiss extract, gamma-cyclodextrin and hydroxypropyl guar gum are according to mass ratio 3-5:1-3:1-3:3-5:
3-5:15-20:5-10 composition.
The present invention also provides a kind of preparation methods of the sun-proof synergistic composition of plant origin, it is characterised in that using following
Step:
A, 3-5:1-3:1-3:3-5:3-5:15-20:5-10 in mass ratio weighs hydrolysis rice bran extract, graywacke rose
Common vetch flower/leaf/stem extraction, marigold flower extract, navel shape seaweed extract, edelweiss extract, gamma-cyclodextrin and hydroxyl
Propyl guar gum；
B, the weighed hydrolysis rice bran extract of step A, cistus incanus flower/leaf/stem extraction, marigold flower are extracted
Object, navel shape seaweed extract, edelweiss extract pour into ethyl alcohol and are stirred dissolution, and it is molten that ethyl alcohol is obtained after being completely dissolved
Liquid；
C, the weighed gamma-cyclodextrin of step A is add to deionized water, is mixed slowly at normal temperature to being completely dissolved,
Obtain gamma-cyclodextrin aqueous solution；
D, ethanol solution obtained by step B is mixed with gamma-cyclodextrin aqueous solution obtained by step C, is used under room temperature
IKA blender 3500rpm is stirred 8 hours, is then placed on 5 DEG C of refrigerators and is stood 24 hours, obtains gamma-cyclodextrin inclusion complex in solution；
E, the weighed hydroxypropyl guar gum of step A is added in the gamma-cyclodextrin inclusion complex in solution of D step preparation, stirring
It is 0.7mm, gas flow 600L/h, injector temperature 120- in nozzle diameter using spray-dried instrument to being completely dissolved
150 DEG C, under the conditions of outlet temperature is 80-90 DEG C, up to a kind of sun-proof synergistic composition of plant origin after spray drying.
Plant is in order to resist environmental injury, and especially to the ultraviolet light of higher-energy, blue light was adapted in evolution and environment
Cheng Zhong can naturally synthesize some sun-prevention components, while thermal burn in order to prevent, can also generate it is some resist it is infrared or by infrared ray
Restoration and protection ingredient after burning.Compared with chemically synthesized sun-screening agent, although the anti-sunlight function of natural products is weaker, but still
So efficient combination can be carried out by the screening and extraction to these natural products, as sun-proof synergist, it is sun-proof to improve tradition
The SPF of formula, preventing coating protection ability of the enhancing product to consumer.The present invention is by grinding various plants extract
Study carefully, filters out five kinds and be combined.
Contain oryzanol in rice bran extract (HYDROLYZED RICE BRAN EXTRACT) of the present invention
(ORYZANOL), the ultraviolet light to wavelength within the scope of 300-320nm has strong absorption.The navel shape seaweed (PORPHYRA
UMBILICALIS) extract contains class bacterium spore element amino acid (MAAs), is using cyclonene as basic framework, with inhomogeneity
The major class water-soluble substances that type amino acid is formed by amine condensation, it is ultraviolet within the scope of 320nm-340nm to wavelength
Line has strong absorption.Cistus incanus (CISTUS INCANUS) flower/leaf/stem extraction contains isoquercitrin
(ISOQUERCITRIN) it links the glucosides to be formed with glucose for Quercetin, has anti-inflammatory, anti-oxidant and anti-light aging function
Effect.Marigold (TAGETES ERECTA) flower extract contains lutein (XANTHOPHYLL), belong to carotenoid at
Point, there is strong absorption to visible blue of the wavelength within the scope of 400-500nm.Edelweiss (the LEONTOPODIUM
ALPINUM) extract contains 2-[(3S)-3-hydroxybutanate (Leontopodic Acid), has and inhibits matrix metalloproteinase and protection DNA
Effect, reduce near infrared light near infrared ray IRA (700-1000nm) loss to skin.
As a further improvement of the present invention, the oryzanol content in the rice bran extract is not less than 25%；The navel shape
Class bacterium spore element amino acid (MAAs) content in seaweed (PORPHYRA UMBILICALIS) extract is not less than 10%；The ash
Isoquercitrin (ISOQUERCITRIN) content in white cistus creticus (CISTUS INCANUS) flower/leaf/stem extraction is not less than 15%；
Lutein content in marigold (TAGETES ERECTA) flower extract is not less than 10%；The edelweiss
2-[(3S)-3-hydroxybutanate (Leontopodic Acid) content in (LEONTOPODIUM ALPINUM) extract is not less than 5%.
Gamma-cyclodextrin of the present invention is the production of WACKER company, trade name CAVAMAX W8 food.
Hydroxypropyl guar gum of the present invention is the Jaguar HP-105 of SOLVAY production.
The present invention includes hydrolysis rice bran extract, cistus incanus flower/leaf/stem extraction, ten thousand by gamma-cyclodextrin first
Longevity chrysanthemum extract, navel shape seaweed extract, edelweiss extract, formed gamma-cyclodextrin inclusion compound, then pass through by
The method of gamma-cyclodextrin inclusion compound and hydroxypropyl guar gum mixing improves gamma-cyclodextrin inclusion hydrolysis rice bran extract, ash
Dissolution after white cistus creticus/leaf/stem extraction, marigold flower extract, navel shape seaweed extract, edelweiss extract
Degree, gains good water solubility, addition in formula are easy-to-use.
The present invention by selection hydrolysis rice bran extract, navel shape seaweed extract, cistus incanus flower/leaf/stem extraction,
Marigold flower extract, edelweiss extract are compounded according to special ratios, can absorb UVB, UVA, visible blue and close
Infrared light removes free radical, protection DNA, inhibits inflammatory factor and matrix metalloproteinase, reduces the light injury that skin is subject to.
Product of the present invention makes an addition to sunscreen formulas, can have the function of synergy to the sun-proof result of common sunscreen product, improve
The sun-proof SPF index of conventional formulation meets and protects more broadband, and the protection including blue wave band and near infrared band needs
It asks.
The experiment that hydroxypropyl guar gum promotes gamma-cyclodextrin inclusion compound dissolubility
Gamma-cyclodextrin is respectively 25g/100ml, 65g/ in 20 DEG C, 40 DEG C, 60 DEG C and 80 DEG C of solubility in water
100ml, 125 g/100ml and 200 g/100ml measure gamma-cyclodextrin its solubility after absorption includes active matter through experiment
It is substantially reduced.1-5:1 in mass ratio weighs the gamma-cyclodextrin inclusion compound and hydroxypropyl guar gum of different proportion, measures hydroxyl
Influence of the addition of propyl guar gum to gamma-cyclodextrin inclusion compound solubility, experimental result such as table 1:
Table 1
The compounding that can be seen that gamma-cyclodextrin and hydroxypropyl guar gum from above-mentioned experimental result, improves gamma-cyclodextrin
The solubility of inclusion compound.The meaning for increasing the meltage of active constituent in water is that this can be convenient a greater amount of in formula
Use, to further increase sun-proof synergistic effect.Because only that the ingredient of dissolution could sufficiently spread over skin surface, more
Sun-proof synergistic effect is played well.
It weighs by embodiment 3 hereinafter, a kind of sun-proof synergistic composition 1mg of plant origin of preparation pours into 250ml
Volumetric flask measures it in 200- using 300 ultraviolet-uisible spectrophotometer of Agilent Cary with deionized water constant volume
The absorption of 800nm, experimental result is as shown in Figure 1, abscissa is wavelength in Fig. 1, and ordinate is trap, as can be seen from Figure 1 this hair
A kind of sun-proof synergistic composition of plant origin of bright preparation is in UVB wave band 291.13nm, UVA wave band 332.11nm, it is seen that blue
Light 497.86nm has absorption, illustrates the sun-proof synergistic composition of plant origin prepared by the present invention really in visible blue wavelengths
And UVB, UVA have absorption, and then prove it with sun-proof synergistic effect.
The sun-proof synergistic composition 3mg for weighing a kind of plant origin of the preparation of embodiment 3 pours into 250ml volumetric flask, spends
Ionized water constant volume measures it in the absorption of 900-1700nm, experimental result using Nicolet S410 near infrared spectrometer
As shown in Fig. 2, abscissa is wavelength in Fig. 2, ordinate is trap, a kind of sun-proof synergy of plant origin prepared by the present invention
Wave band of the composition in near-infrared 900-1000nm has absorption, illustrates white powder prepared by the present invention really near infrared band
There is absorption, meets the protection requirements of near infrared band.
A kind of sun-proof synergistic composition of plant origin prepared by the present invention is to spf value synergy test experiments
Choose healthy volunteer 40, male 17, women 23, the age 20-58 year old, be averaged (27.6 ± 4.5) year, both
Toward unglazed perceptual history of disease, be not used influences photosensitive drug at no distant date, no serious systemic disease, immune deficiency or itself exempts from
Epidemic disease disease, to cosmetics without allergy, facial no acute inflammation, hormone medicine or immunosuppressor is not used, do not participate in it
His clinical test, does not smear external preparation.4 groups are randomly divided into, every group of 10 people, wherein 3 groups of smearings add the embodiment of 5% content
1, a kind of sun-proof synergistic composition of plant origin prepared by 2,3, in addition 1 group of smearing blank group sample.According to " cosmetics peace
Full technical specification " measuring method of (version in 2010) about sunscreen cosmetic SPF (spf value), measure sample SPF value.
A kind of sun-proof synergistic composition of plant origin prepared by embodiment 1,2,3 at being grouped as such as table 2:
Table 2
Sunscreen Base Formula such as table 3:
Table 3
Measurement according to " cosmetics safety technical specification " (version in 2010) about sunscreen cosmetic SPF (spf value)
Method, 1,2,3 group of the sample and blank group human body SPF test result of test addition object of the present invention are as shown in table 4:
Table 4
| Sample number into spectrum | Sample 1 | Sample 2 | Sample 3 | Blank group |
| Spf value | 22.5 | 23.8 | 23.5 | 16.2 |
Find out from upper table test result, adds the sun-proof synergistic composition of 5% plant origin of the present invention, have to spf value bright
Aobvious synergistic function, addition 5% can averagely improve spf value 6 or so.
Detailed description of the invention
Fig. 1 is the sun-proof synergistic composition UV absorption wave spectrogram of plant origin；
Fig. 2 is the sun-proof synergistic composition near infrared absorption wave spectrogram of plant origin.
Specific embodiment
Embodiment 1:
A kind of sun-proof synergistic composition of plant origin, it is characterised in that prepared using following methods:
A. in mass ratio 3: 1: 1.5: 3.4: 3.4: 16.2: 5.8 hydrolysis rice bran extract is weighed
175.0g, cistus incanus flower/leaf/stem extraction 58.4g, marigold flower extract 87.4g, navel shape seaweed extract
198.2g, edelweiss extract, gamma-cyclodextrin 944.6g and hydroxypropyl guar gum 338.2g；
B. the weighed hydrolysis rice bran extract of step A institute, cistus incanus flower/leaf/stem extraction, marigold flower are extracted
After object, navel shape seaweed extract, the mixing of edelweiss extract, pours into 7172.0g ethyl alcohol and be stirred dissolution, obtain second
Alcoholic solution；
C. the weighed gamma-cyclodextrin of step A is added in 5667.6g deionized water, is mixed slowly under room temperature to dissolution,
Obtain gamma-cyclodextrin aqueous solution；
D. ethanol solution obtained by step B is mixed with gamma-cyclodextrin aqueous solution obtained by step C, is stirred under room temperature with IKA
It mixes device 3500rpm to stir 8 hours, is then placed on 5 DEG C of refrigerators and stands 24 hours, obtain clear gamma-cyclodextrin inclusion complex in solution；
E. the weighed hydroxypropyl guar gum of step A is added in the gamma-cyclodextrin inclusion complex in solution of D step preparation, stirring
To being completely dissolved, using BUCHI Mini S Spray Dryer B-290 spray-dried instrument, nozzle diameter 0.7mm, gas
Flow is 600L/h, and injector temperature is 120 DEG C, and outlet temperature is 82 DEG C, and a kind of homogeneous white powder is prepared
The as sun-proof synergistic composition of plant origin.
Embodiment 2:
A kind of sun-proof synergistic composition of plant origin, it is characterised in that prepared using following methods:
A. in mass ratio 3.8: 2.0: 2.0: 3.6: 3.8: 17.4: 6.5 hydrolysis rice bran extract is weighed
194.4g, cistus incanus flower/leaf/stem extraction 102.4g, marigold flower extract 102.4g, navel shape seaweed extract
184.0g, edelweiss extract 194.4g, gamma-cyclodextrin 890.0g and hydroxypropyl guar gum 332.4g；
B. the weighed hydrolysis rice bran extract of step A institute, cistus incanus flower/leaf/stem extraction, marigold flower are extracted
It is poured into 7776.0g ethyl alcohol after object, navel shape seaweed extract, the mixing of edelweiss extract and is stirred dissolution, obtain second
Alcoholic solution；
C. the weighed gamma-cyclodextrin of step A is added in 6230.0g deionized water, is mixed slowly under room temperature to dissolution,
Obtain gamma-cyclodextrin aqueous solution；
D. ethanol solution obtained by step B is mixed with gamma-cyclodextrin aqueous solution obtained by step C, is stirred under room temperature with IKA
It mixes device 3500rpm to stir 8 hours, is then placed on 5 DEG C of refrigerators and stands 24 hours, obtain clear gamma-cyclodextrin inclusion complex in solution；
E. the weighed hydroxypropyl guar gum of step A is added in the gamma-cyclodextrin inclusion complex in solution of D step preparation, stirring
To being completely dissolved, using BUCHI Mini S Spray Dryer B-290 spray-dried instrument, nozzle diameter 0.7mm, gas
Flow is 600L/h, and injector temperature is 130 DEG C, and outlet temperature is 84 DEG C, and a kind of homogeneous white powder is prepared
The as sun-proof synergistic composition of plant origin.
Embodiment 3:
A kind of sun-proof synergistic composition of plant origin, it is characterised in that prepared using following methods:
A. in mass ratio 4.0: 1.5: 2.4: 4.2: 3.8: 18.0: 7.0 hydrolysis rice bran extract is weighed
195.6g, cistus incanus flower/leaf/stem extraction 73.4g, marigold flower extract 117.4g, navel shape seaweed extract
205.4g, edelweiss extract 185.8g, gamma-cyclodextrin 880.2g and hydroxypropyl guar gum 342.2g；
B. the weighed hydrolysis rice bran extract of step A institute, cistus incanus flower/leaf/stem extraction, marigold flower are extracted
It is poured into 7776.0g ethyl alcohol after object, navel shape seaweed extract, the mixing of edelweiss extract and is stirred dissolution, obtain second
Alcoholic solution；
C. the weighed gamma-cyclodextrin of step A is added in 7041.6g deionized water, obtains gamma-cyclodextrin aqueous solution；
D. ethanol solution obtained by step B is mixed with gamma-cyclodextrin aqueous solution obtained by step C, is stirred under room temperature with IKA
It mixes device 3500rpm to stir 8 hours, is then placed on 5 DEG C of refrigerators and stands 24 hours, obtain clear gamma-cyclodextrin inclusion complex in solution；
E. the weighed hydroxypropyl guar gum of step A is added in the gamma-cyclodextrin inclusion complex in solution of D step preparation, stirring
To being completely dissolved, using BUCHI Mini S Spray Dryer B-290 spray-dried instrument, nozzle diameter 0.7mm, gas
Flow is 600L/h, and injector temperature is 138 DEG C, and outlet temperature is 86 DEG C, and a kind of homogeneous white powder is prepared
The as sun-proof synergistic composition of plant origin.
Embodiment 4:
A kind of sun-proof synergistic composition of plant origin, it is characterised in that prepared using following methods:
A. in mass ratio 4.4: 2.4: 2.6: 4.0: 4.0: 18.5: 8.0 hydrolysis rice bran extract is weighed
200.4g, cistus incanus flower/leaf/stem extraction 109.4g, marigold flower extract 118.4g, navel shape seaweed extract
182.2g, edelweiss extract 182.2g, gamma-cyclodextrin 842.8g and hydroxypropyl guar gum 364.6g；
B. the weighed hydrolysis rice bran extract of step A institute, cistus incanus flower/leaf/stem extraction, marigold flower are extracted
It is poured into 7926.0g ethyl alcohol after object, navel shape seaweed extract, the mixing of edelweiss extract and is stirred dissolution, obtain second
Alcoholic solution；
C. the weighed gamma-cyclodextrin of step A is added in 7585.2g deionized water, is mixed slowly under room temperature to dissolution,
Obtain gamma-cyclodextrin aqueous solution；
D. ethanol solution obtained by step B is mixed with gamma-cyclodextrin aqueous solution obtained by step C, is stirred under room temperature with IKA
It mixes device 3500rpm to stir 8 hours, is then placed on 5 DEG C of refrigerators and stands 24 hours, obtain clear gamma-cyclodextrin inclusion complex in solution；
E. the weighed hydroxypropyl guar gum of step A is added in the gamma-cyclodextrin inclusion complex in solution of D step preparation, stirring
To being completely dissolved, using BUCHI Mini S Spray Dryer B-290 spray-dried instrument, nozzle diameter 0.7mm, gas
Flow is 600L/h, and injector temperature is 142 DEG C, and outlet temperature is 88 DEG C, and a kind of homogeneous white powder is prepared
The as sun-proof synergistic composition of plant origin.
Embodiment 5:
A kind of sun-proof synergistic composition of plant origin, it is characterised in that prepared using following methods:
A. in mass ratio 4.8: 2.8: 2.6: 4.4: 4.6: 18.5: 9.0 hydrolysis rice bran extract is weighed
205.6g, cistus incanus flower/leaf/stem extraction 120.0g, marigold flower extract 111.4g, navel shape seaweed extract
188.4g, edelweiss extract 197.0g, gamma-cyclodextrin 792.2g and hydroxypropyl guar gum 385.4g；
B. the weighed hydrolysis rice bran extract of step A institute, cistus incanus flower/leaf/stem extraction, marigold flower are extracted
It is poured into 8224.0g ethyl alcohol after object, navel shape seaweed extract, the mixing of edelweiss extract and is stirred dissolution, obtain second
Alcoholic solution；
C. the weighed gamma-cyclodextrin of step A is added in 7922.0g deionized water, is mixed slowly under room temperature to dissolution,
Obtain gamma-cyclodextrin aqueous solution；
D. ethanol solution obtained by step B is mixed with gamma-cyclodextrin aqueous solution obtained by step C, is stirred under room temperature with IKA
It mixes device 3500rpm to stir 8 hours, is then placed on 5 DEG C of refrigerators and stands 24 hours, obtain clear gamma-cyclodextrin inclusion complex in solution；
E. the weighed hydroxypropyl guar gum of step A is added in the gamma-cyclodextrin inclusion complex in solution of D step preparation, stirring
To being completely dissolved, using BUCHI Mini S Spray Dryer B-290 spray-dried instrument, nozzle diameter 0.7mm, gas
Flow is 600L/h, and injector temperature is 150 DEG C, and outlet temperature is 90 DEG C, and a kind of homogeneous white powder is prepared
The as sun-proof synergistic composition of plant origin.
The above description is only an embodiment of the present invention, is not intended to limit the scope of the invention, all to utilize this hair
Equivalent structure or equivalent flow shift made by bright description is applied directly or indirectly in other relevant technology necks
Domain is included within the scope of the present invention.
Claims (2)
1. a kind of sun-proof synergistic composition of plant origin, it is characterised in that: by hydrolysis rice bran extract, cistus incanus flower/
Leaf/stem extraction, marigold flower extract, navel shape seaweed extract, edelweiss extract, gamma-cyclodextrin and hydroxypropyl
Guar gum is formed according to mass ratio 3-5:1-3:1-3:3-5:3-5:15-20:5-10；Paddy in the hydrolysis rice bran extract
It ties up cellulose content and is not less than 25%；Class bacterium spore element amino acid content in the navel shape seaweed extract is not less than 10%；It is described greyish white
Isoquercitrin content in cistus creticus/leaf/stem extraction is not less than 15%；Lutein content in the marigold flower extract
Not less than 10%；2-[(3S)-3-hydroxybutanate content in the edelweiss extract is not less than 5%.
2. the preparation method of the sun-proof synergistic composition of plant origin described in claim 1, it is characterised in that use following steps:
A, 3-5:1-3:1-3:3-5:3-5:15-20:5-10 in mass ratio weigh hydrolysis rice bran extract, cistus incanus flower/
Leaf/stem extraction, marigold flower extract, navel shape seaweed extract, edelweiss extract, gamma-cyclodextrin and hydroxypropyl
Guar gum；Oryzanol content in the hydrolysis rice bran extract is not less than 25%；Class bacterium spore in the navel shape seaweed extract
Plain amino acid content is not less than 10%；Isoquercitrin content in the cistus incanus flower/leaf/stem extraction is not less than 15%；Institute
The lutein content in marigold flower extract is stated not less than 10%；2-[(3S)-3-hydroxybutanate content in the edelweiss extract
Not less than 5%；
B, by the weighed hydrolysis rice bran extract of step A, cistus incanus flower/leaf/stem extraction, marigold flower extract, navel
Shape seaweed extract, edelweiss extract, which pour into ethyl alcohol, is stirred dissolution, obtains ethanol solution after being completely dissolved；
C, the weighed gamma-cyclodextrin of step A is add to deionized water, is mixed slowly at normal temperature to being completely dissolved, obtains γ-
Cyclodextrin aqueous solution；
D, ethanol solution obtained by step B is mixed with gamma-cyclodextrin aqueous solution obtained by step C, is stirred under room temperature with IKA
It mixes device 3500rpm to stir 8 hours, is then placed on 5 DEG C of refrigerators and stands 24 hours, obtain gamma-cyclodextrin inclusion complex in solution；
E, the weighed hydroxypropyl guar gum of step A is added in the gamma-cyclodextrin inclusion complex in solution of D step preparation, has been stirred to
Fully dissolved is 0.7mm, gas flow 600L/h, injector temperature 120-150 in nozzle diameter using spray-dried instrument
DEG C, under the conditions of outlet temperature is 80-90 DEG C, up to a kind of sun-proof synergistic composition of plant origin after spray drying.
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| CN110974765B (en) * | 2020-01-15 | 2021-06-15 | 芭芭多芦荟生物科技研究(广州)院 | Natural whitening mask and preparation method and application thereof |
| CN111821235A (en) * | 2020-07-13 | 2020-10-27 | 植物医生(广东)生物科技有限公司 | Photo-protection plant extraction composition and application thereof |
| CN112545942A (en) * | 2020-12-18 | 2021-03-26 | 深圳市琉璃光生物科技有限公司 | Plant extract composition, sunscreen composition and preparation method thereof |
| CN113197793B (en) * | 2021-04-15 | 2022-03-04 | 广州天玺生物科技有限公司 | Blue light resistant composition and preparation method and application thereof |
| CN115487080A (en) * | 2022-09-23 | 2022-12-20 | 山东博科医用材料有限公司 | Bavacrol microcapsule and preparation method thereof |
| CN115252512B (en) * | 2022-09-29 | 2022-12-13 | 美尚(广州)化妆品股份有限公司 | Sunscreen composition and preparation method and application thereof |
| CN117503626B (en) * | 2023-11-09 | 2024-04-16 | 植物医生(广东)生物科技有限公司 | Plant-derived sun-screening synergistic composition, sun-screening product, preparation method and application |
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