CN106170470B - 制造15-羟基脂肪酸衍生物的方法 - Google Patents

制造15-羟基脂肪酸衍生物的方法 Download PDF

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Publication number
CN106170470B
CN106170470B CN201480071389.7A CN201480071389A CN106170470B CN 106170470 B CN106170470 B CN 106170470B CN 201480071389 A CN201480071389 A CN 201480071389A CN 106170470 B CN106170470 B CN 106170470B
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China
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fatty acid
less
dgla
enzyme
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CN201480071389.7A
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Chinese (zh)
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CN106170470A (zh
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M·曼库
D·科兰
B·道恩斯
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Af Immunology Co ltd
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Honorable Science Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN201480071389.7A 2013-10-29 2014-10-29 制造15-羟基脂肪酸衍生物的方法 Active CN106170470B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361896901P 2013-10-29 2013-10-29
US61/896,901 2013-10-29
PCT/IB2014/003086 WO2015063617A2 (en) 2013-10-29 2014-10-29 Methods of making 15-hydroxy fatty acid derivatives

Publications (2)

Publication Number Publication Date
CN106170470A CN106170470A (zh) 2016-11-30
CN106170470B true CN106170470B (zh) 2019-06-18

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ID=52669636

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CN201480071389.7A Active CN106170470B (zh) 2013-10-29 2014-10-29 制造15-羟基脂肪酸衍生物的方法

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US (1) US9670126B2 (https=)
EP (1) EP3063118B1 (https=)
JP (1) JP6659557B2 (https=)
CN (1) CN106170470B (https=)
ES (1) ES2670776T3 (https=)
WO (1) WO2015063617A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018003569A1 (ja) * 2016-06-30 2018-01-04 備前化成株式会社 ω３およびω６不飽和脂肪酸酸化物の製造方法
US20240000680A1 (en) * 2019-12-06 2024-01-04 Kolon Industries, Inc. Mono-hydroxy or di-hydroxy derivatives of polyunsaturated fatty acids, production method therefor, and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69524639T2 (de) * 1994-10-13 2002-08-08 Peptech Ltd., North Ryde Modifizierte mehrfach ungesättigte fettsäuren
US20040122126A1 (en) * 2002-12-20 2004-06-24 Dong Wu Free-radical initiator systems containing enzymes, compositions, and methods
US7893106B2 (en) * 2004-11-19 2011-02-22 Martek Biosciences, Corporation Oxylipins from stearidonic acid and γ-linolenic acid and methods of making and using the same
NZ578368A (en) * 2006-12-20 2011-02-25 Protech Res Pty Ltd Extraction and purification of lipoxygenase from soy beans
JP2010110246A (ja) * 2008-11-05 2010-05-20 Kao Corp ９位過酸化脂肪酸の製造方法

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
《Asymmetric synthesis of unnatural (Z,Z,E)-octadecatrienoid and eicosatrienoid by lipoxygenase-catalyzed oxygenation》;S. Nanda et al.;《Tetrahedron: Asymmetry》;20030704;第14卷(第13期);1799–1806 *
《Biocatalytic hydroxylation of linoleic acid in a double-fed batch system with lipoxygenase and cysteine》;Michel B. W. Elshof et al.;《EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY》;19981231;第100卷(第6期);246–251 *
《On the specificity of oxygenation of unsaturated fatty acids catalyzed by soybean lipoxygenase》;Mats Hamberg et al.;《J. Biol. Chem.》;19671231;第242卷(第22期);5329-5335 *
《Structural Requirements for the Inhibition of 5-Lipoxygenase by15-Hydroxyeicosa-5,8,11,13-tetraenoiAc cid Analogues》;Fortuna Haviv et al.;《J. Med. Chem.》;19871231;第30卷(第2期);254-263 *

Also Published As

Publication number Publication date
WO2015063617A2 (en) 2015-05-07
US20150119593A1 (en) 2015-04-30
CN106170470A (zh) 2016-11-30
EP3063118B1 (en) 2018-04-18
JP6659557B2 (ja) 2020-03-04
JP2016537411A (ja) 2016-12-01
ES2670776T3 (es) 2018-06-01
WO2015063617A3 (en) 2015-08-06
US9670126B2 (en) 2017-06-06
EP3063118A2 (en) 2016-09-07

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