CN106164097A - 用于预防和治疗出血的半衰期延长的因子fviia以及为此的给药方案 - Google Patents
用于预防和治疗出血的半衰期延长的因子fviia以及为此的给药方案 Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461978218P | 2014-04-11 | 2014-04-11 | |
| US61/978,218 | 2014-04-11 | ||
| EP14167612.2 | 2014-05-09 | ||
| EP14167612 | 2014-05-09 | ||
| EP14168389 | 2014-05-15 | ||
| EP14168389.6 | 2014-05-15 | ||
| PCT/AU2015/050137 WO2015154139A1 (en) | 2014-04-11 | 2015-03-30 | Half-life extended factor fviia protein for prevention and treatment of bleeding and dosing regimens therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106164097A true CN106164097A (zh) | 2016-11-23 |
Family
ID=54287020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580018873.8A Withdrawn CN106164097A (zh) | 2014-04-11 | 2015-03-30 | 用于预防和治疗出血的半衰期延长的因子fviia以及为此的给药方案 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20170042981A1 (https=) |
| EP (1) | EP3129408A4 (https=) |
| JP (1) | JP2017513831A (https=) |
| KR (1) | KR20160143820A (https=) |
| CN (1) | CN106164097A (https=) |
| AU (1) | AU2015245941A1 (https=) |
| BR (1) | BR112016023158A2 (https=) |
| CA (1) | CA2944174A1 (https=) |
| MX (1) | MX2016013281A (https=) |
| RU (1) | RU2016144159A (https=) |
| SG (1) | SG11201608006QA (https=) |
| WO (1) | WO2015154139A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110799209A (zh) * | 2017-06-29 | 2020-02-14 | 康诺贝林伦瑙有限公司 | 用于预防性治疗血友病的包含因子ix和人白蛋白的融合蛋白的21天给药方案及其方法 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007090584A1 (en) * | 2006-02-06 | 2007-08-16 | Csl Behring Gmbh | Modified coagulation factor vila with extended half-life |
| CN101557830A (zh) * | 2006-12-15 | 2009-10-14 | 巴克斯特国际公司 | 具有延长的体内半衰期的因子VIIa-聚唾液酸结合物 |
| WO2012002745A3 (en) * | 2010-06-30 | 2012-04-26 | Hanmi Holdings Co., Ltd | Factor viia complex using an immunoglobulin fragment |
| US20130243747A1 (en) * | 2006-02-03 | 2013-09-19 | Prolor Biotech Inc. | Long-acting coagulation factors and methods of producing same |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011020866A2 (en) * | 2009-08-20 | 2011-02-24 | Csl Behring Gmbh | Albumin fused coagulation factors for non-intravenous administration in the therapy and prophylactic treatment of bleeding disorders |
-
2015
- 2015-03-30 BR BR112016023158A patent/BR112016023158A2/pt not_active Application Discontinuation
- 2015-03-30 RU RU2016144159A patent/RU2016144159A/ru not_active Application Discontinuation
- 2015-03-30 SG SG11201608006QA patent/SG11201608006QA/en unknown
- 2015-03-30 CN CN201580018873.8A patent/CN106164097A/zh not_active Withdrawn
- 2015-03-30 CA CA2944174A patent/CA2944174A1/en not_active Abandoned
- 2015-03-30 US US15/302,597 patent/US20170042981A1/en not_active Abandoned
- 2015-03-30 KR KR1020167031632A patent/KR20160143820A/ko not_active Withdrawn
- 2015-03-30 WO PCT/AU2015/050137 patent/WO2015154139A1/en not_active Ceased
- 2015-03-30 EP EP15775929.1A patent/EP3129408A4/en not_active Withdrawn
- 2015-03-30 MX MX2016013281A patent/MX2016013281A/es unknown
- 2015-03-30 JP JP2016561735A patent/JP2017513831A/ja active Pending
- 2015-03-30 AU AU2015245941A patent/AU2015245941A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130243747A1 (en) * | 2006-02-03 | 2013-09-19 | Prolor Biotech Inc. | Long-acting coagulation factors and methods of producing same |
| WO2007090584A1 (en) * | 2006-02-06 | 2007-08-16 | Csl Behring Gmbh | Modified coagulation factor vila with extended half-life |
| CN101557830A (zh) * | 2006-12-15 | 2009-10-14 | 巴克斯特国际公司 | 具有延长的体内半衰期的因子VIIa-聚唾液酸结合物 |
| WO2012002745A3 (en) * | 2010-06-30 | 2012-04-26 | Hanmi Holdings Co., Ltd | Factor viia complex using an immunoglobulin fragment |
Non-Patent Citations (1)
| Title |
|---|
| THOMAS WEIMER ET AL.: "Prolonged in-vivo half-life of factor VIIa by fusion to albumin", 《THROMB HAEMOST》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110799209A (zh) * | 2017-06-29 | 2020-02-14 | 康诺贝林伦瑙有限公司 | 用于预防性治疗血友病的包含因子ix和人白蛋白的融合蛋白的21天给药方案及其方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| SG11201608006QA (en) | 2016-10-28 |
| JP2017513831A (ja) | 2017-06-01 |
| CA2944174A1 (en) | 2015-10-15 |
| AU2015245941A1 (en) | 2016-11-17 |
| MX2016013281A (es) | 2017-01-18 |
| BR112016023158A2 (pt) | 2017-10-17 |
| RU2016144159A3 (https=) | 2018-11-26 |
| US20170042981A1 (en) | 2017-02-16 |
| EP3129408A1 (en) | 2017-02-15 |
| WO2015154139A1 (en) | 2015-10-15 |
| EP3129408A4 (en) | 2018-04-25 |
| RU2016144159A (ru) | 2018-05-11 |
| KR20160143820A (ko) | 2016-12-14 |
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| WW01 | Invention patent application withdrawn after publication | ||
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Application publication date: 20161123 |