CN106139128A - A kind of moisturizing antibacterial liquid and preparation method thereof - Google Patents
A kind of moisturizing antibacterial liquid and preparation method thereof Download PDFInfo
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- CN106139128A CN106139128A CN201510186741.8A CN201510186741A CN106139128A CN 106139128 A CN106139128 A CN 106139128A CN 201510186741 A CN201510186741 A CN 201510186741A CN 106139128 A CN106139128 A CN 106139128A
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Abstract
The invention discloses a kind of moisturizing antibacterial liquid and preparation method thereof, it is the moisturizing antibacterial liquid being prepared as by following raw material: golden cypress, frutus cnidii, Asian puccoon, benzalkonium bromide, tea oil, menthol, borneol, aloe powder, Hydrolyzed Collagen, poly glycol monomethyl ether, by golden cypress, frutus cnidii, after Asian puccoon mixes in proportion, pulverize, carry out soak extraction with ethanol solution, extract is concentrated into relative density 1.01～1.03, add benzalkonium bromide, tea oil, menthol, borneol, aloe powder, Hydrolyzed Collagen, after poly glycol monomethyl ether mixed dissolution, add water blended, filter, stand, filling moisturizing antibacterial liquid.The present invention nurses medicament safety non-toxic, can bactericidal antiphlogistic, antipruritic, moisturizing, have good effects for irritant dermatitis, fungal infection, particularly notable to the effect such as Labia Minora/Pruritus vulvae, peculiar smell.
Description
Technical field
The present invention relates to pharmaceutical preparation, specifically a kind of moisturizing antibacterial liquid and preparation method thereof.
Background technology
Society, is incremented by owing to many factors causes suffering from skin disease crowd in number foot year soon, and disease of skin has become a kind of dermatosis chronic disease repeatedly common, multiple, easy.Skin disease Signs is at table, for common disease, frequently-occurring disease, severe patient can affect the study of patient, work and life, and skin disease is of a great variety, the cause of disease is complicated, and the pathogenesis of multiple dermatosis is still less clear and definite so far, the obstinate difficulty of illness heals, from pathology, cannot treat different things as the same because skin disease is of a great variety, western medical treatment skin disease instant effect, but easily recurrence bounce-back, caused by with the addition of hormone in medicine.So that the recurrence bounce-back tossed about of a lot of conditions of patients, and increase the weight of time by time, have no alternative！Lose the confidence for the treatment of.The traditional Chinese medical science uses traditional Chinese medical herbal treatment, the especially dermatosis chronic disease to chronic disease, has extraordinary curative effect, by clinical verification, has reflected and got the nod, be included into national development strategy for this Development of Chinese Medicine.
In Chinese Patent Application No.: 200910074188.3 disclose a kind of pudendum-cleaning lotion and preparation method thereof, its composition of raw materials jin number meter by weight: kuh-seng 10-90 part, root bark of shaggy-fruited dittany 5-90 part, golden cypress 1-60 part, bark of eucommia 5-85 part, parasitic 10-90 part, Radix Angelicae Sinensis 1-50 part, tarragon 3-90 part.But patient is relatively strong to the dependence of this medicament, and the preparation process of this medicament is complicated, relatively costly, has the limitation of himself simultaneously.
Product of the present invention without hormonal components, clinical practice show nontoxic, corrosion-free, have no side effect, compared with antibacterial liquid similar with existing market, product purpose of the present invention is not single product, and effect is notable.It is applicable to the problem skin disease crowd that many reasons causes.Such as eczema, nettle rash, acne, scabies, bleb, seborrhea, heat-rash, pruitus, tinea pedis, dermatitis, cutaneous pruritus, fungus-caused vaginitis etc. can be tackled.It is suitable for the application of all kinds of skin diseases, have good treatment and prevention effect, notable to the effect such as Labia Minora/Pruritus vulvae, peculiar smell.
Content of the invention
It is an object of the invention to provide a kind of moisturizing antibacterial liquid and preparation method thereof.This lotion prescription is reasonable, giving consideration to both the incidental and fundamental, and curative effect is lasting, and clinical effectiveness is notable.
A kind of moisturizing antibacterial liquid provided by the present invention and preparation method thereof, is made by the raw material of following weight proportion: golden cypress 36～80 jin, frutus cnidii 36～80 jin, Asian puccoon 15～45 jin.Golden cypress, frutus cnidii, Asian puccoon are mixed according to above-mentioned weight proportion, pulverize, carry out soak extraction with ethanol solution, extract is concentrated into relative density 1.01～1.03, add benzalkonium bromide 500～1000 grams, tea oil 80～240 grams, menthol 80～240 grams, borneol 80～240 grams, aloe powder 80～240 grams, Hydrolyzed Collagen 80～240 grams, poly glycol monomethyl ether 80～240 grams, add 50～150 liters of water water blended, filter, stand, filling moisturizing antibacterial liquid.
The present invention nurses medicament safety non-toxic, can bactericidal antiphlogistic, antipruritic, moisturizing, good effects is had to irritant dermatitis, fungal infection, particularly notable to the effect such as Labia Minora/Pruritus vulvae, peculiar smell.Formula raw material are readily available, and low price, production cost is low.This product makes nursing become simpler, mitigates the anaclisis of patient, promotes its psychological rehabilitation, establish the confidence of Fighting Disease.
The moisturizing antibacterial liquid preparation method of the present invention is:
1st, after golden cypress, frutus cnidii, Asian puccoon being mixed in proportion, pulverize, soak at normal temperatures with 40% ethanol solution of raw material gross weight 5～6 times, filter after soaking two weeks, obtain filtrate；
2nd, taking supernatant after above-mentioned filtered fluid being stood 24 hours and both having can get golden cypress, frutus cnidii, the ethanol extract of Asian puccoon, it is 1.01～1.03 that extract is concentrated into proportion, obtains concentrate；3rd, after adding benzalkonium bromide, tea oil, menthol, borneol, aloe powder, Hydrolyzed Collagen, poly glycol monomethyl ether mixed dissolution in above-mentioned concentrate, the blended stirring of water, filtration, standing, filling moisturizing antibacterial liquid are added.
The moisturizing antibacterial liquid of the present invention is made up of the common Chinese herbal medicine of golden cypress, frutus cnidii, a few taste of Asian puccoon, is aided with tea oil, aloe powder, Hydrolyzed Collagen natural component, adds benzalkonium bromide, menthol, poly glycol monomethyl ether composition.Asian puccoon cures mainly: cool blood, invigorates blood circulation, promoting eruption of detoxifying, for blood-head poison contain, macula purple is black, measles without adequate eruption, sore, eczema, scald, clearing heat and cooling blood, is used for measles, pyreticosis ecchymosis, eczema, hematuria, blood drenches, bloody flux, sore, erysipelas, burn, constipation with heat retention, other Asian puccoon has more the effect of significant anti-acne and anti-inflammatory, has very big its cosmetic values.Tea oil has effects such as improving dysmenorrhoea, irregular menstruation and genital infection.Hydrolyzed Collagen firm skin, crease-resistant effect.Benzalkonium bromide this product is one of the most frequently used surfactant, there is cleaning, sterilizing and algae removal effect, be widely used in the aspects such as sterilization, sterilization, anticorrosion, emulsification, de-sludging, solubilising, have that toxicity is little, water soluble, not by the water hardness affected, easy to use, low cost and other advantages.Poly glycol monomethyl ether has good water solubility, wetability, lubricity, physiological inertia, non-stimulated, gentle to human body, is widely used in cosmetics and pharmaceuticals industry.It in pharmaceuticals industry, is used as the matrix of ointment, emulsion, ointment, lotion and suppository.
The existing lubrication of moisturizing antibacterial liquid of the present invention, the effect of firm skin have again effect clearing heat and detoxicating, sterilizing and itch-relieving, it is adaptable to the problem skin disease crowd that many reasons causes.Have preferably prevention and result for the treatment of for all kinds of skin diseases such as eczema, nettle rash, acne, bleb, seborrhea, heat-rash, pruitus, tinea pedis, cutaneous pruritus, fungus-caused vaginitis and gynecological disease.
Detailed description of the invention
Embodiment 1: a kind of moisturizing antibacterial liquid and preparation method thereof, take golden cypress 36 jin, frutus cnidii 36 jin, Asian puccoon 15 jin is as raw material, mix after pulverizing, 40% ethanol solution adding raw material gross weight 5～6 times soaks at normal temperatures, filter after soaking two weeks, obtain filtrate, take supernatant after filtered fluid is stood 24 hours and both can get golden cypress, frutus cnidii and the ethanol extract of Asian puccoon, extract is concentrated into relative density 1.01～1.03, add benzalkonium bromide 500 grams, tea oil 80 grams, menthol 80 grams, borneol 80 grams, aloe powder 80 grams, Hydrolyzed Collagen 80 grams, 80 grams of mixed dissolutions of poly glycol monomethyl ether, add distilled water diluting to 50 liters of stirrings, obtain finished product liquid.
Embodiment 2: a kind of moisturizing antibacterial liquid and preparation method thereof, take golden cypress 36 jin, frutus cnidii 36 jin, Asian puccoon 15 jin is as raw material, mix after pulverizing, 40% ethanol solution adding raw material gross weight 5～6 times soaks at normal temperatures, filter after soaking two weeks, obtain filtrate, take supernatant after filtered fluid is stood 24 hours and both can get golden cypress, frutus cnidii and the ethanol extract of Asian puccoon, extract is concentrated into relative density 1.01～1.03, add benzalkonium bromide 750 grams, tea oil 160 grams, menthol 80 grams, borneol 80 grams, aloe powder 80 grams, Hydrolyzed Collagen 80 grams, 80 grams of mixed dissolutions of poly glycol monomethyl ether, add distilled water diluting to 50 liters of stirrings, obtain finished product liquid.
Embodiment 3: a kind of moisturizing antibacterial liquid and preparation method thereof, take golden cypress 60 jin, frutus cnidii 60 jin, Asian puccoon 30 jin is as raw material, mix after pulverizing, 40% ethanol solution adding raw material gross weight 5～6 times soaks at normal temperatures, filter after soaking two weeks, obtain filtrate, take supernatant after filtered fluid is stood 24 hours and both can get golden cypress, frutus cnidii and the ethanol extract of Asian puccoon, extract is concentrated into relative density 1.01～1.03, add benzalkonium bromide 750 grams, tea oil 80 grams, menthol 80 grams, borneol 80 grams, aloe powder 80 grams, Hydrolyzed Collagen 160 grams, 80 grams of mixed dissolutions of poly glycol monomethyl ether, add distilled water diluting to 50 liters of stirrings, obtain finished product liquid.
Embodiment 4: a kind of moisturizing antibacterial liquid and preparation method thereof, take golden cypress 36 jin, frutus cnidii 36 jin, Asian puccoon 15 jin is as raw material, mix after pulverizing, 40% ethanol solution adding raw material gross weight 5～6 times soaks at normal temperatures, filter after soaking two weeks, obtain filtrate, take supernatant after filtered fluid is stood 24 hours and both can get golden cypress, frutus cnidii and the ethanol extract of Asian puccoon, extract is concentrated into relative density 1.01～1.03, add benzalkonium bromide 500 grams, tea oil 160 grams, menthol 80 grams, borneol 80 grams, aloe powder 80 grams, Hydrolyzed Collagen 160 grams, 80 grams of mixed dissolutions of poly glycol monomethyl ether, add distilled water diluting to 50 liters of stirrings, obtain finished product liquid.
Embodiment 5: a kind of moisturizing antibacterial liquid and preparation method thereof, take golden cypress 80 jin, frutus cnidii 80 jin, Asian puccoon 45 jin is as raw material, mix after pulverizing, 40% ethanol solution adding raw material gross weight 5～6 times soaks at normal temperatures, filter after soaking two weeks, obtain filtrate, take supernatant after filtered fluid is stood 24 hours and both can get golden cypress, frutus cnidii and the ethanol extract of Asian puccoon, extract is concentrated into relative density 1.01～1.03, add benzalkonium bromide 1000 grams, tea oil 240 grams, menthol 240 grams, borneol 240 grams, aloe powder 240 grams, Hydrolyzed Collagen 240 grams, 240 grams of mixed dissolutions of poly glycol monomethyl ether, add distilled water diluting to 150 liters of stirrings, obtain finished product liquid.
Claims (8)
1. a moisturizing antibacterial liquid, it is characterized in that making by the raw material of following weight proportion: golden cypress 36～80 jin, frutus cnidii 36～80 jin, Asian puccoon 15～45 jin, is aided with benzalkonium bromide 500～1000 grams, tea oil 80～240 grams, menthol 80～240 grams, borneol 80～240 grams, aloe powder 80～240 grams, Hydrolyzed Collagen 80～240 grams, poly glycol monomethyl ether 80～240 grams and 50～150 liters of water.
2. the preparation method of moisturizing antibacterial liquid described in claim 1, it is characterized in that mixing golden cypress, frutus cnidii, Asian puccoon according to above-mentioned weight proportion, pulverize, carry out soak extraction with ethanol solution, add benzalkonium bromide, tea oil, menthol, borneol, aloe powder, Hydrolyzed Collagen, after poly glycol monomethyl ether mixed dissolution, add that water is blended, filter, stand, filling moisturizing antibacterial liquid.
3. the preparation method of moisturizing antibacterial liquid according to claim 1, it is characterised in that:
Including once step:
1) after golden cypress, frutus cnidii, Asian puccoon being mixed in proportion, pulverize, soak at normal temperatures with 40% ethanol solution of raw material gross weight 5～6 times, filter after soaking two weeks, obtain filtrate；2) taking supernatant after above-mentioned filtered fluid being stood 24 hours and both having can get golden cypress, frutus cnidii, the ethanol extract of Asian puccoon, it is 1.01～1.03 that extract is concentrated into proportion, obtains concentrate；3), after adding benzalkonium bromide, tea oil, menthol, borneol, aloe powder, Hydrolyzed Collagen, poly glycol monomethyl ether mixed dissolution in above-mentioned concentrate, the blended stirring of water, filtration, standing, filling moisturizing antibacterial liquid are added.
4. the preparation method of moisturizing antibacterial liquid according to claim 3, it is characterized in that: take golden cypress 36 jin, frutus cnidii 36 jin, Asian puccoon 15 jin is as raw material, mix after pulverizing, 40% ethanol solution adding raw material gross weight 5～6 times soaks at normal temperatures, filter after soaking two weeks, obtain filtrate, take supernatant after filtered fluid is stood 24 hours and both can get golden cypress, frutus cnidii and the ethanol extract of Asian puccoon, extract is concentrated into relative density 1.01～1.03, add benzalkonium bromide 500 grams, tea oil 80 grams, menthol 80 grams, borneol 80 grams, aloe powder 80 grams, Hydrolyzed Collagen 80 grams, 80 grams of mixed dissolutions of poly glycol monomethyl ether, add distilled water diluting to 50 liters of stirrings, obtain finished product liquid.
5. the preparation method of moisturizing antibacterial liquid according to claim 3, it is characterized in that: produce the material quantity of extract and extract concentrates with claim 4, add benzalkonium bromide 750 grams, tea oil 160 grams, menthol 80 grams, borneol 80 grams, aloe powder 80 grams, Hydrolyzed Collagen 80 grams, 80 grams of mixed dissolutions of poly glycol monomethyl ether, add distilled water diluting to 50 liters of stirrings, obtain finished product liquid.
6. the preparation method of moisturizing antibacterial liquid according to claim 3, it is characterized in that: produce the material quantity of extract and extract concentrates with claim 4, add benzalkonium bromide 750 grams, tea oil 80 grams, menthol 80 grams, borneol 80 grams, aloe powder 80 grams, Hydrolyzed Collagen 160 grams, 80 grams of mixed dissolutions of poly glycol monomethyl ether, add distilled water diluting to 50 liters of stirrings, obtain finished product liquid.
7. the preparation method of moisturizing antibacterial liquid according to claim 3, it is characterized in that: produce the material quantity of extract and extract concentrates with claim 4, add benzalkonium bromide 500 grams, tea oil 160 grams, menthol 80 grams, borneol 80 grams, aloe powder 80 grams, Hydrolyzed Collagen 160 grams, 80 grams of mixed dissolutions of poly glycol monomethyl ether, add distilled water diluting to 50 liters of stirrings, obtain finished product liquid.
8. the preparation method of moisturizing antibacterial liquid according to claim 3, it is characterized in that: take golden cypress 80 jin, frutus cnidii 80 jin, Asian puccoon 45 jin is as raw material, mix after pulverizing, 40% ethanol solution adding raw material gross weight 5～6 times soaks at normal temperatures, filter after soaking two weeks, obtain filtrate, take supernatant after filtered fluid is stood 24 hours and both can get golden cypress, frutus cnidii and the ethanol extract of Asian puccoon, extract is concentrated into relative density 1.01～1.03, add benzalkonium bromide 1000 grams, tea oil 240 grams, menthol 240 grams, borneol 240 grams, aloe powder 240 grams, Hydrolyzed Collagen 240 grams, 240 grams of mixed dissolutions of poly glycol monomethyl ether, add distilled water diluting to 150 liters of stirrings, obtain finished product liquid.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106075070A (en) * | 2016-07-26 | 2016-11-09 | 济南市儿童医院 | A kind of unguentum treating children's's urticaria and preparation method thereof |
| CN107412643A (en) * | 2017-05-20 | 2017-12-01 | 连云港康肤药业有限公司 | A kind of external preparation for skin sterilizes antibacterial emulsifiable paste and preparation method thereof |
| CN107714812A (en) * | 2017-11-24 | 2018-02-23 | 凯格尔品牌运营（西安）有限公司 | A kind of male's privates multi-functional traditional Chinese medicine lotion and preparation method thereof |
| CN112773860A (en) * | 2021-01-18 | 2021-05-11 | 澳邦制药(横琴)有限公司 | Wanying ointment and preparation method thereof |
Citations (2)
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| CN101396507A (en) * | 2008-10-31 | 2009-04-01 | 山西振东制药有限公司 | Traditional Chinese medicine antibacterial liquid and preparation method and use thereof |
| CN101690785A (en) * | 2009-10-15 | 2010-04-07 | 贵州百灵企业集团制药股份有限公司 | Bacteriostatic lotion and preparation method thereof |
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2015
- 2015-04-20 CN CN201510186741.8A patent/CN106139128A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101396507A (en) * | 2008-10-31 | 2009-04-01 | 山西振东制药有限公司 | Traditional Chinese medicine antibacterial liquid and preparation method and use thereof |
| CN101690785A (en) * | 2009-10-15 | 2010-04-07 | 贵州百灵企业集团制药股份有限公司 | Bacteriostatic lotion and preparation method thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106075070A (en) * | 2016-07-26 | 2016-11-09 | 济南市儿童医院 | A kind of unguentum treating children's's urticaria and preparation method thereof |
| CN107412643A (en) * | 2017-05-20 | 2017-12-01 | 连云港康肤药业有限公司 | A kind of external preparation for skin sterilizes antibacterial emulsifiable paste and preparation method thereof |
| CN107714812A (en) * | 2017-11-24 | 2018-02-23 | 凯格尔品牌运营（西安）有限公司 | A kind of male's privates multi-functional traditional Chinese medicine lotion and preparation method thereof |
| CN112773860A (en) * | 2021-01-18 | 2021-05-11 | 澳邦制药(横琴)有限公司 | Wanying ointment and preparation method thereof |
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Application publication date: 20161123 |