CN106138659A - 一种治疗痹症的中药组合物 - Google Patents

一种治疗痹症的中药组合物 Download PDF

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CN106138659A
CN106138659A CN201610701270.4A CN201610701270A CN106138659A CN 106138659 A CN106138659 A CN 106138659A CN 201610701270 A CN201610701270 A CN 201610701270A CN 106138659 A CN106138659 A CN 106138659A
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姚洪超
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Abstract

本发明涉及一种治疗痹症的中药组合物，其中药原料及重量份配比为：天仙藤10‑30份、凤尾参5‑25份、桂枝5‑20份、两面针5‑25份、桑枝5‑25份、大萼鹿角藤 5‑20份、昂天莲5‑25份、薜荔根5‑25份、山茱萸5‑25份、羌活5‑20份、狗脊5‑25份、木瓜5‑25份、刺龙牙5‑25份、肿节风5‑25份、饭团根5‑20份、巴戟天5‑25份、七叶莲5‑25份、五加皮5‑25份、知母5‑20份、血风藤5‑25份、一支箭5‑25份、穿破石5‑25份、甘草5‑15份。本发明的中药组合物具有补益肝肾、行气活血、清热除湿、祛风通络、消肿止痛的功效，其治疗痹症疗效显著，作用可靠。

Description

一种治疗痹症的中药组合物
技术领域
本发明涉及一种传统草药的未确定结构的医药配制品，尤其是一种治疗痹症的中药组合物。
背景技术
痹症(Bi syndrome)是指人体机表、经络因感受风、寒、湿、热等引起的以肢体关节及肌肉酸痛、麻木、屈伸不利，甚或关节肿大灼热等为主症的一类病症。临床上有渐进性或反复发作性的特点。临床症状：双手指、双脚趾、腕、踝等小关节首先发病，晨间出现关节僵硬，并有浑身不适。西医一般采用非甾体类药物，如消炎痛、布洛芬、萘普生、芬必得等治疗，这种疗法虽然见效明显，但也只能暂时缓解症状。而且长期服用，对肝、胆、心血管、脑血管，以及凝血机制均有一定的副作用。
中医认为，痹症主要病机是气血痹阻不通，筋脉关节失于濡养，且与外感风寒湿热之邪和人体正气不足有关。
根据中医理论，针对痹症的发病机理，采用补益肝肾、行气活血、清热除湿、祛风通络、消肿止痛的治法，进行辩证配伍组方，以达到标本兼治的目的。
发明内容
为了克服现有技术中治疗痹症存在只能暂时缓解症状及一定的副作用的不足，本发明提供一种配制简便、成本低、疗效显著、无副作用的治疗痹症的中药组合物。
本发明解决其技术问题所采用的技术方案是：一种治疗痹症的中药组合物，其特征在于：其中药原料及重量份配比为：天仙藤10-30份、凤尾参5-25份、桂枝5-20份、两面针5-25份、桑枝5-25份、大萼鹿角藤 5-20份、昂天莲5-25份、薜荔根5-25份、山茱萸5-25份、羌活5-20份、狗脊5-25份、木瓜5-25份、刺龙牙5-25份、肿节风5-25份、饭团根5-20份、巴戟天5-25份、七叶莲5-25份、五加皮5-25份、知母5-20份、血风藤5-25份、一支箭5-25份、穿破石5-25份、甘草5-15份。
本发明的优选技术方案是：一种治疗痹症的中药组合物，其特征在于：其中药原料及重量份配比为：天仙藤20份、凤尾参15份、桂枝10份、两面针15份、桑枝15份、大萼鹿角藤10份、昂天莲15份、薜荔根15份、山茱萸15份、羌活10份、狗脊15份、木瓜15份、刺龙牙15份、肿节风15份、饭团根10份、巴戟天15份、七叶莲15份、五加皮15份、知母10份、血风藤15份、一支箭15份、穿破石15份、甘草10份。
本发明中药组合物是在传统中医理论和临床经验指导下，精选药物组方。本发明中药组合物中：天仙藤具有行气化湿、活血止痛的功效；凤尾参具有补气血、强筋骨、健脾胃的功效；桂枝具有发汗解肌、温经通脉、助阳化气、散寒止痛的功效；两面针具有行气止痛、活血化瘀、祛风通络的功效；桑枝具有祛风湿、利关节的功效；大萼鹿角藤具有通经活络、活血止痛、接骨生肌、降压的功效；昂天莲具有通经活血、消肿止痛的功效；薜荔根具有祛风除湿、舒筋通络的功效；山茱萸具有补益肝肾、涩精固脱的功效；羌活具有散寒解表、祛风胜湿、除痹止痛的功效；狗脊具有补肝肾、强腰脊、祛风湿、利关节的功效；木瓜具有破血行气、通经止痛的功效；刺龙牙具有益气补肾、祛风利湿、活血止痛的功效；肿节风具有祛风除湿、活血散瘀、清热解毒的功效；饭团根具有行气活血、散瘀止痛的功效；巴戟天具有补肾助阳、强筋壮骨、祛风除湿的功效；七叶莲具有祛风止痛、活血消肿的功效；五加皮具有祛风湿、补肝肾、强筋骨的功效；知母具有清热泻火、生津润燥的功效；血风藤具有补益气血、祛风活络的功效；一支箭具有清热解毒、活血散瘀的功效；穿破石具有祛风通络、清热除湿、解毒消肿的功效；甘草具有补脾益气、清热解毒、祛痰止咳、调和诸药的功效。本发明精选药物组方，其药物组分经辩证配伍，在作用上相互佐助，共奏补益肝肾、行气活血、清热除湿、祛风通络、消肿止痛的功效，对痹症的治疗达到标本兼治。
本发明组合物的组分均采用天然的中药原料，其配制简便、药源广、成本低。本发明遵循中医的处方用药原则，各种组分药物采用水煎服用。经临床应用验证和中药品不良反应（ADR）安全性评价，其疗效显著，安全可靠，药性平和，未出现毒副作用，有效率达96%，治愈率79%。
具体实施方式
下面结合实施例对本发明作进一步说明。
实施例1
一种治疗痹症的中药组合物，其中药原料及重量配比为：天仙藤20g、凤尾参15g、桂枝10g、两面针15g、桑枝15g、大萼鹿角藤 10g、昂天莲15g、薜荔根15g、山茱萸15g、羌活10g、狗脊15g、木瓜15g、刺龙牙15g、肿节风15g、饭团根10g、巴戟天15g、七叶莲15g、五加皮15g、知母10g、血风藤15g、一支箭15g、穿破石15g、甘草10g。
实施例2
一种治疗痹症的中药组合物，其中药原料及重量配比为：天仙藤15g、凤尾参25g、桂枝12g、两面针20g、桑枝5g、大萼鹿角藤 15g、昂天莲10g、薜荔根20g、山茱萸5g、羌活15g、狗脊10g、木瓜20g、刺龙牙5g、肿节风25g、饭团根12g、巴戟天20g、七叶莲5g、五加皮25g、知母12g、血风藤20g、一支箭5g、穿破石25g、甘草12g。
实施例3
一种治疗痹症的中药组合物，其中药原料及重量配比为：天仙藤25g、凤尾参5g、桂枝20g、两面针10g、桑枝25g、大萼鹿角藤 5g、昂天莲20g、薜荔根10g、山茱萸25g、羌活5g、狗脊20g、木瓜10g、刺龙牙25g、肿节风5g、饭团根20g、巴戟天10g、七叶莲25g、五加皮5g、知母20g、血风藤10g、一支箭25g、穿破石5g、甘草8g。
实施例4
一种治疗痹症的中药组合物，其中药原料及重量配比为：天仙藤10g、凤尾参20g、桂枝5g、两面针25g、桑枝10g、大萼鹿角藤 20g、昂天莲5g、薜荔根25g、山茱萸10g、羌活20g、狗脊5g、木瓜25g、刺龙牙10g、肿节风20g、饭团根5g、巴戟天25g、七叶莲10g、五加皮20g、知母5g、血风藤25g、一支箭10g、穿破石20g、甘草5g。
实施例5
一种治疗痹症的中药组合物，其中药原料及重量配比为：天仙藤30g、凤尾参10g、桂枝15g、两面针5g、桑枝20g、大萼鹿角藤 12g、昂天莲25g、薜荔根5g、山茱萸20g、羌活12g、狗脊25g、木瓜5g、刺龙牙20g、肿节风10g、饭团根15g、巴戟天5g、七叶莲20g、五加皮10g、知母15g、血风藤5g、一支箭20g、穿破石10g、甘草15g。
本发明实施例中的中药组合物按常规的水煎法制取药剂。具体方法如下：将组方的中药原料放入容器中，加冷水漫过药面，浸泡15～20分钟，再加水没过药面约6厘米，进行第一次煎煮，未沸前采用武火煎煮，沸后用文火煎煮20～30分钟；第二次煎煮，加水没过药面约4厘米，水沸后煎煮15～20分钟。两次煎煮取汁，合并。
本发明以实施例1所给出的一种治疗痹症的中药组合物，做临床疗效总结如下：
一、一般性资料：本中药组合物应用于临床观察病例95例，男52例，女43例，年龄35～75岁。
二、临床表现：
自觉肢体关节肌肉疼痛、屈伸不利；或游走不定，恶风寒；或痛剧，遇寒则甚，得热则缓；或重着而痛，手足笨重，活动不灵，肌肤麻木不仁；或肢体关节疼痛，痛处红灼热，筋脉拘急；或关节剧痛，肿大变形，也有绵绵而痛，麻木尤甚伴心悸、乏力。
三、用法用量：临床应用时，一日一剂，水煎两遍取汁约400ml，分早、晚两次空腹温服。六天为一疗程。治疗期间忌生冷辛辣刺激之物。
四、疗效标准：
(1) 治愈：肢体关节疼痛消失，其他伴随症状恢复正常；
(2) 有效：肢体关节疼痛明显减轻，其他伴随症状也明显好转；
(3) 无效：肢体关节疼痛及伴随症状无明显改善。
五、治疗效果：该临床观察病例中，服药2-5个疗程，痊愈75例，随访未见复发；有效16例，无效4例。治疗期间对中药品临床引起各类型的过敏反应、疑为药物引起人体各系统、器官、组织的功能和形态方面的异常、疑为药物引起癌症等致突变反应、药物的依赖性以及认为重要或有价值的其他不良反应进行了评价，即中药品不良反应（ADR）评价，未发生不良反应和毒副作用。
六、典型病例：
病例1：
姜某，男，53岁。双手腕、手指及双膝关节对称性疼痛、肿胀，遇冷加重，活动受限，形体消瘦，面色无华。诊见：舌质淡红，苔薄白，脉沉细。诊断为：痹症。服用本发明中药组合物制备的药剂2个疗程，关节疼痛肿胀明显减轻；继续服药2个疗程，肢体关节疼痛及其他伴随症状完全消失，治愈。
病例 2 ：
迟某，女，45 岁。肢体关节酸痛、沉重、肿胀、屈伸不利，遇阴雨天气症状加重，伴心悸、乏力、恶寒发热。诊见者：舌质红，苔黄腻，脉细数。诊断为：痹症。服用本发明中药组合物制备的药剂3个疗程，自觉关节酸痛、肿胀明显减轻，心悸、乏力等伴随症状消失；继续服药2个疗程，所有症状完全消失，治愈。

Claims (2)

1.一种治疗痹症的中药组合物，其特征在于：其中药原料及重量份配比为：天仙藤10-30份、凤尾参5-25份、桂枝5-20份、两面针5-25份、桑枝5-25份、大萼鹿角藤 5-20份、昂天莲5-25份、薜荔根5-25份、山茱萸5-25份、羌活5-20份、狗脊5-25份、木瓜5-25份、刺龙牙5-25份、肿节风5-25份、饭团根5-20份、巴戟天5-25份、七叶莲5-25份、五加皮5-25份、知母5-20份、血风藤5-25份、一支箭5-25份、穿破石5-25份、甘草5-15份。
2.根据权利要求1所述一种治疗痹症的中药组合物，其特征在于：其中药原料及重量份配比为：天仙藤20份、凤尾参15份、桂枝10份、两面针15份、桑枝15份、大萼鹿角藤 10份、昂天莲15份、薜荔根15份、山茱萸15份、羌活10份、狗脊15份、木瓜15份、刺龙牙15份、肿节风15份、饭团根10份、巴戟天15份、七叶莲15份、五加皮15份、知母10份、血风藤15份、一支箭15份、穿破石15份、甘草10份。
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