CN106138609A - A kind of ERZHI WAN of tonifying kidney and nourishing liver and preparation method thereof - Google Patents

A kind of ERZHI WAN of tonifying kidney and nourishing liver and preparation method thereof Download PDF

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Publication number
CN106138609A
CN106138609A CN201610611547.4A CN201610611547A CN106138609A CN 106138609 A CN106138609 A CN 106138609A CN 201610611547 A CN201610611547 A CN 201610611547A CN 106138609 A CN106138609 A CN 106138609A
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parts
fructus
tonifying kidney
nourishing liver
nourishing
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CN201610611547.4A
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Inventor
曹剑
施鼎铭
施深海
陈方谭
厉云彪
陆娟
刘兴约
卢晓智
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PAN'AN FOREIGN TRADE MEDICINE Co Ltd ZHEJIANG CHINA
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PAN'AN FOREIGN TRADE MEDICINE Co Ltd ZHEJIANG CHINA
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Priority to CN201610611547.4A priority Critical patent/CN106138609A/en
Publication of CN106138609A publication Critical patent/CN106138609A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/894—Dioscoreaceae (Yam family)
    • A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/62—Nymphaeaceae (Water-lily family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/638—Ligustrum, e.g. Chinese privet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734—Crataegus (hawthorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses ERZHI WAN of a kind of tonifying kidney and nourishing liver and preparation method thereof, the ERZHI WAN of this tonifying kidney and nourishing liver is made up of following weight composition: Fructus Ligustri Lucidi 50 100 parts, Herba Ecliptae 50 90 parts, Fructus Mori 10 25 parts, Radix Polygoni Multiflori 12 20 parts, the Cortex Eucommiae 17 parts, Rhizomadioscoreae 36 parts, Semen Euryales 1 12 parts, Fructus Lycii 25 parts and Fructus Crataegi 10 13 parts, the ERZHI WAN of the tonifying kidney and nourishing liver of the present invention uses Fructus Mori and Radix Polygoni Multiflori, coordinate other various Chinese medicines and traditional Fructus Ligustri Lucidi mixing manufacture again, there is nourishing skin care, invigorating the spleen and replenishing QI, strengthening the spleen and nourishing the stomach, only sweating due to debility, nourishing YIN and supplementing blood, reduce blood glucose, tonifying kidney and nourishing liver, reduce effect of cholesterol.

Description

A kind of ERZHI WAN of tonifying kidney and nourishing liver and preparation method thereof
Technical field
The present invention relates to ERZHI WAN of a kind of tonifying kidney and nourishing liver and preparation method thereof.
Background technology
Modern medicine study thinks that Fructus Ligustri Lucidi can suppress the effect of helicobacter pylori, can treat gastropathy, also have and press down Purine abnormal metabolism processed, for ventilating and the treatment of hyperuricemia.Traditional ERZHI WAN is mixed only with Fructus Ligustri Lucidi and Herba Ecliptae Conjunction decocts into pill, although making very simple, but effect is the most single, and drug effect does not has highly significant.
Summary of the invention
The technical problem to be solved is to provide the ERZHI WAN of a kind of tonifying kidney and nourishing liver, nourishes skin care, invigorating the spleen and replenishing QI, Strengthening the spleen and nourishing the stomach, only sweating due to debility, nourishing YIN and supplementing blood, reduces blood glucose, reduces effect of cholesterol.
For solving the problems referred to above, the present invention is achieved through the following technical solutions: the ERZHI WAN of a kind of tonifying kidney and nourishing liver, The ERZHI WAN of this tonifying kidney and nourishing liver is made up of following weight composition: Fructus Ligustri Lucidi 50-100 part, Herba Ecliptae 50-90 part, Mulberry Shen 10-25 part, Radix Polygoni Multiflori 12-20 part, Cortex Eucommiae 1-7 part, Rhizomadioscoreae 3-6 part, Semen Euryales 1-12 part, Fructus Lycii 2-5 part and Fructus Crataegi 10-13 Part.
Another technical problem to be solved by this invention is to provide the preparation method of the ERZHI WAN of a kind of tonifying kidney and nourishing liver,
The present invention is achieved through the following technical solutions: the preparation process of the ERZHI WAN of described tonifying kidney and nourishing liver is as follows:
1) extract Fructus Ligustri Lucidi 50-100 part, destemming leaf by weight ratio, be immersed in one day night in wine, wipe skin, shine Dry, grind into powder；
2) extracting Herba Ecliptae 50-90 part by weight ratio, smash to pieces as juice, 100 degree of high temperature decoct 4 hours；
3) Fructus Mori 10-25 part, Radix Polygoni Multiflori 12-20 part, Cortex Eucommiae 1-7 part, Rhizomadioscoreae 3-6 part, Semen Euryales are extracted by weight ratio 1-12 part, Fructus Lycii 2-5 part and Fructus Crataegi 10-13 part wash clean respectively, dries, and container grind into powder is put in mixing；
4) mixed-powder of extraction step 3 uniformly mixes with the Fructus Ligustri Lucidi powder of step 1；
5) mixture of extraction step 4 is slowly put into the Herba Ecliptae dope of step 2 and is stirred together and heat；
6) mixture of extraction step 5 is fabricated to ball cooling and is ERZHI WAN.
The ERZHI WAN of tonifying kidney and nourishing liver of the present invention, its medical material efficacy effect is respectively as follows: 1, Fructus Ligustri Lucidi: have reduction blood Fat, prevention of arterial hardens, drops hypoglycemic effect；2, Herba Ecliptae: there is enhancing non-specific immunity and cellular immune function, right Chromosome damage has certain protective effect；3, Fructus Mori: there is nourishing YIN and supplementing blood, the effect of intestine moistening of promoting the production of body fluid；4, Radix Polygoni Multiflori: there is solution Poison, intestine moistening pain are flat, and blood fat reducing promotes hemopoietic function, enhancing immunity, protects the liver, effect of slow down aging；5, the Cortex Eucommiae: there is benefit Liver and kidney, bone and muscle strengthening, blood pressure lowering, antiabortive effect；6, Semen Euryales: there is supplementing the kidney to control the nocturnal, tonifying spleen and stopping diarrhea, effect of damp eliminating leukorrhagia stopping；7、 Fructus Lycii: there is caused by liver and kidney deficiency；Have a dizzy spell；The most unclear；Soreness of the waist and knees；Impotence and seminal emission；Cough due to consumptive disease；Quench one's thirst the merit of taking fluids profusely Effect；8, Rhizomadioscoreae: have spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, effect of the kidney invigorating arresting seminal emission；9, Fructus Crataegi: have promoting digestion and invigorating the stomach, activating blood circulation to dissipate blood stasis, Effect of convergence dysentery relieving.
The invention has the beneficial effects as follows: use Fructus Mori and Radix Polygoni Multiflori, then coordinate other various Chinese medicines and traditional Fructus Ligustri Lucidi Mixing manufacture, has nourishing skin care, invigorating the spleen and replenishing QI, strengthening the spleen and nourishing the stomach, only sweating due to debility, nourishing YIN and supplementing blood, reduces blood glucose, tonifying kidney and nourishing liver, fall Effect of low cholesterol.
Detailed description of the invention
Following example are used for illustrating the present invention, but are not limited to the scope of the present invention.
Embodiment 1
The ERZHI WAN of a kind of tonifying kidney and nourishing liver of the present invention, the ERZHI WAN of this tonifying kidney and nourishing liver is by following weight composition Composition: Fructus Ligustri Lucidi 50 parts, Herba Ecliptae 50 parts, Fructus Mori 10 parts, Radix Polygoni Multiflori 12 parts, the Cortex Eucommiae 1 part, Rhizomadioscoreae 3 parts, Semen Euryales 1 part, Fructus Lycii 2 Part and Fructus Crataegi 10 parts.
The preparation process of the ERZHI WAN of described tonifying kidney and nourishing liver is as follows:
1) extract Fructus Ligustri Lucidi 50 parts, destemming leaf by weight ratio, be immersed in one day night in wine, wipe skin, dry, grind Clay into power；
2) extracting Herba Ecliptae 50 parts by weight ratio, smash to pieces as juice, 100 degree of high temperature decoct 4 hours；
3) Fructus Mori 10 parts, Radix Polygoni Multiflori 12 parts, the Cortex Eucommiae 1 part, Rhizomadioscoreae 3 parts, Semen Euryales 1 part, Fructus Lycii 2 parts are extracted by weight ratio With Fructus Crataegi 10 parts wash clean respectively, drying, container grind into powder is put in mixing；
4) mixed-powder of extraction step 3 uniformly mixes with the Fructus Ligustri Lucidi powder of step 1；
5) mixture of extraction step 4 is slowly put into the Herba Ecliptae dope of step 2 and is stirred together and heat；
6) mixture of extraction step 5 is fabricated to ball cooling and is ERZHI WAN.
Embodiment 2
Its difference from Example 1 is, the ERZHI WAN of this tonifying kidney and nourishing liver is made up of following weight composition: Fructus Ligustri Lucidi 100 parts, Herba Ecliptae 90 parts, Fructus Mori 25 parts, Radix Polygoni Multiflori 20 parts, the Cortex Eucommiae 7 parts, Rhizomadioscoreae 6 parts, Semen Euryales 12 parts, Fructus Lycii 5 parts and Fructus Crataegi 13 parts.
Experimental basis,
1, experimental subject: the patient suffering from cholesterol 20 is divided into 2 groups, often organizes 10 people.
2, experimental technique: allow 10 people's normal diets of matched group, 10 people of experimental group eat the ERZHI WAN of tonifying kidney and nourishing liver, often Take hundred night, the most edible 15 days.
3, experimental result:
From experimental result, the present invention has the effect reducing cholesterol.
Typical case
Wang, man, 67 years old, the soreness of waist was unable, and blood pressure, blood glucose are too high, perspire abnormal sweat.After the most edible one month, blood glucose is obvious Reducing, muscle power increases, and old man no longer gets up in the night to urinate, and the most no longer perspires abnormal sweat.
Experimental basis, the schoolgirl wax yellow to 10 pachylosiies eats every day, and every day is edible once, can be according to self-condition Edible, the most edible one month, skin had obvious improvement, change more smooth, ruddy, and therefore, the present invention has nourishing and supports Face, invigorating the spleen and replenishing QI, effect of strengthening the spleen and nourishing the stomach.
Experimental basis, man weak to 20, sweating due to debility, frequent micturition eats every day, and every day, with (medicine) to be taken with wine hundred, eats continuously After half wheat harvesting period, evening, sweating due to debility was not the most flowed in sleep, and frequent micturition there has also been improvement clearly, and therefore, the present invention only has Sweating due to debility, effect of suppression frequent micturition.
The present invention is not limited to above-mentioned preferred forms, anyone draw under the enlightenment of the present invention other any with Product as the present invention is same or like, within all falling within protection scope of the present invention.

Claims (2)

1. the ERZHI WAN of a tonifying kidney and nourishing liver, it is characterised in that: the ERZHI WAN of this tonifying kidney and nourishing liver is to be become by following weight Part composition: Fructus Ligustri Lucidi 50-100 part, Herba Ecliptae 50-90 part, Fructus Mori 10-25 part, Radix Polygoni Multiflori 12-20 part, Cortex Eucommiae 1-7 part, Rhizomadioscoreae 3-6 part, Semen Euryales 1-12 part, Fructus Lycii 2-5 part and Fructus Crataegi 10-13 part.
2. the preparation method of the ERZHI WAN of a tonifying kidney and nourishing liver as claimed in claim 1, it is characterised in that: described tonifying kidney and nourishing liver The preparation process of ERZHI WAN as follows:
1) extract Fructus Ligustri Lucidi 50-100 part, destemming leaf by weight ratio, be immersed in one day night in wine, wipe skin, dry, grind Clay into power；
2) extracting Herba Ecliptae 50-90 part by weight ratio, smash to pieces as juice, 100 degree of high temperature decoct 4 hours；
3) Fructus Mori 10-25 part, Radix Polygoni Multiflori 12-20 part, Cortex Eucommiae 1-7 part, Rhizomadioscoreae 3-6 part, Semen Euryales 1-12 are extracted by weight ratio Part, Fructus Lycii 2-5 part and Fructus Crataegi 10-13 part wash clean respectively, dries, and container grind into powder is put in mixing；
4) mixed-powder of extraction step 3 uniformly mixes with the Fructus Ligustri Lucidi powder of step 1；
5) mixture of extraction step 4 is slowly put into the Herba Ecliptae dope of step 2 and is stirred together and heat；
6) mixture of extraction step 5 is fabricated to ball cooling and is ERZHI WAN.
CN201610611547.4A 2016-07-27 2016-07-27 A kind of ERZHI WAN of tonifying kidney and nourishing liver and preparation method thereof Pending CN106138609A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108802217A (en) * 2018-05-28 2018-11-13 南京中医药大学 The quality control of Chinese medicine compound prescription and evaluation method

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1088447A (en) * 1992-12-22 1994-06-29 福建中医学院 A kind of powerful anti-ageing Chinese patent medicine with anti-aging effects
CN1242993A (en) * 1998-07-23 2000-02-02 宋建祥 Preparation for tonifying kidney and blackening hairs
CN1293992A (en) * 1999-10-21 2001-05-09 陈德才 Medicine 'Buyuan Jianmei Wan'
CN103103081A (en) * 2011-11-15 2013-05-15 伊青 Medicinal wine for tonifying kidney and nourishing liver
CN104587215A (en) * 2015-01-21 2015-05-06 梁黎明 Traditional Chinese medicine composition for treating kidney yin deficiency
CN105106549A (en) * 2015-09-30 2015-12-02 成都倍加特生物科技有限公司 Oral traditional Chinese medicine pill for treating phalacrosis and preparation method of oral traditional Chinese medicine pill
CN105232955A (en) * 2015-11-12 2016-01-13 青岛友诚高新技术有限公司 Traditional Chinese medicine composition capable of tonifying kidneys and preparation method thereof

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1088447A (en) * 1992-12-22 1994-06-29 福建中医学院 A kind of powerful anti-ageing Chinese patent medicine with anti-aging effects
CN1242993A (en) * 1998-07-23 2000-02-02 宋建祥 Preparation for tonifying kidney and blackening hairs
CN1293992A (en) * 1999-10-21 2001-05-09 陈德才 Medicine 'Buyuan Jianmei Wan'
CN103103081A (en) * 2011-11-15 2013-05-15 伊青 Medicinal wine for tonifying kidney and nourishing liver
CN104587215A (en) * 2015-01-21 2015-05-06 梁黎明 Traditional Chinese medicine composition for treating kidney yin deficiency
CN105106549A (en) * 2015-09-30 2015-12-02 成都倍加特生物科技有限公司 Oral traditional Chinese medicine pill for treating phalacrosis and preparation method of oral traditional Chinese medicine pill
CN105232955A (en) * 2015-11-12 2016-01-13 青岛友诚高新技术有限公司 Traditional Chinese medicine composition capable of tonifying kidneys and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108802217A (en) * 2018-05-28 2018-11-13 南京中医药大学 The quality control of Chinese medicine compound prescription and evaluation method
CN108802217B (en) * 2018-05-28 2021-09-14 南京中医药大学 Quality control and evaluation method of Chinese herbal compound

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