CN106138418A - Preparation method of external medicament for treating soft tissue contusion - Google Patents
Preparation method of external medicament for treating soft tissue contusion Download PDFInfo
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- CN106138418A CN106138418A CN201610817041.9A CN201610817041A CN106138418A CN 106138418 A CN106138418 A CN 106138418A CN 201610817041 A CN201610817041 A CN 201610817041A CN 106138418 A CN106138418 A CN 106138418A
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Abstract
A preparation method of an external medicament for treating soft tissue contusion belongs to the technical field of medicines, and aims to solve the soft tissue contusion caused by traumatic injury, and the preparation method is mainly carried out according to the following steps: firstly, raw materials used are as follows: notoginseng radix, radix Dipsaci, Camphora, periostracum Serpentis, radix rehmanniae, flos Lonicerae, radix et rhizoma Rhei, fructus Trichosanthis, exocarpium Benincase, radix Isatidis, semen Persicae, and alcohol; secondly, decocting the himalayan teasel root, the snake slough, the dried rehmannia root, the honeysuckle, the rhubarb, the trichosanthes kirilowii Maxim, the Chinese waxgourd peel, the peach kernel, the radix isatidis and clear water by one liter to obtain liquid medicine; thirdly, distilling and concentrating the liquid medicine to obtain thick and thin paste; fourthly, the temperature of the thin and thick medicine paste obtained by distillation is reduced to 10-25 ℃, then the paste is moved to a sealed drying box, and a drying agent is used for drying to obtain yellow and black dry massive medicine; fifthly, crushing the massive medicine and 7 parts of camphor into mixed medicine powder; sixthly, smashing 10 parts of pseudo-ginseng into pseudo-ginseng medicinal mud; seventhly, adding the panax notoginseng medicine mud and the mixed medicine powder into 50 parts of alcohol, quickly stirring uniformly, bottling and sealing. The medicament prepared by the preparation method of the external medicament for treating the soft tissue contusion has obvious effects of detumescence and acesodyne, and melanin scars are not left after the wound part is healed.
Description
Technical field
The present invention relates to a kind of topical agent manufacture method treating soft tissue contusion, belong to pharmaceutical technology field.
Background technology
Soft tissue injury refers to that the reason such as various acute trauma or chronic strain and oneself disease pathology causes human body
Skin, subcutaneous shallow deep fascia, muscle, tendon, stndon sheath, ligament, joint capsule, synovial bursae, intervertebral disc, peripheral nerve blood vessel etc. are organized
Pathological lesion, referred to as soft tissue injury.Clinical manifestation: pain, swelling, deformity, dysfunction.
The classification of soft tissue injury: sprain class, dampens class, mangled injury class；There are the acute injury of tendon and muscle, Chronic soft tissue injury class；Have
Open injury class, closed injury class etc..The size of wound, shape, bleeding, injured degree and scope, skin with or without
Ecchymosis, vesicle, Pi Wen, with or without change, refers to that (toe) holds loop condition, and muscle, with or without ischemic necrosis, hinders limb whether swelling, skin
Nervous and harden, can be movable, with or without sensory disturbance.
These tissues, by the acting on of different causative factors of injury of external inherence, cause disorganization and tissue physiology's function disorderly
Disorderly produce damage.Soft tissue injury is usually acting on by external mechanism's stress, induces damage when reaching certain intensity,
Produce symptom.Generally can be divided into acute injury and chronic accumulation damage two big classes.When soft tissue is sudden and violent by passivity or sharp property
Power damage time, can cause local soft tissue (include skin, subcutaneous tissue, muscle, wherein include nerve, blood vessel andLymph Tissue) contusion or (with) laceration.Human soft tissue injury is a kind of commonly encountered diseases in human motion system, frequently-occurring disease.
The damage of soft tissue can cause occurring neck shoulder back of the body waist-leg and extremity because of acute injury and chronic accumulation harm
Different situations, disease in various degree, in recent decades, find the significant portion of many diseases derive from soft tissue muscle,
Ligament, fascia, fat, joint capsule, nerve, blood vessel etc. directly cause to send out.Cause harm the biggest.Which the reason that soft tissue contusion occurs has
A bit？Soft tissue contusion is many flutters wound or impact injury because spraining, dampen, fall, and causes the tear of human body local subcutaneous soft tissue hemorrhage or ooze
Go out.
The injury symptoms of soft tissue includes: (1) pain: with the nature and extent of violence, distribution that injury is neural and
The power of inflammatory reaction is relevant.(2) swelling: because of local soft tissue internal hemorrhage or (with) inflammatory reaction oozes out caused.(3) function barrier
Hinder: cause the obstacle of limb function or activity.(4) wound or wound surface: can have different deep according to the violence nature and extent of damage
The wound of degree or skin abrasion etc..
Generally can ease pain, physical therapy, the treatment of the method such as braking.In injured 24 hours, the available cold compress in local, skin can be made
Hair vasoconstriction, tissue edema disappears, and plays the effect of hemostasia and detumescence pain relieving.My section uses the drug of topical application in early days for soft tissue contusion
Method is treated, and has extraordinary curative effect, is one of the big characteristic of traumatological department of TCM's treatment.
The general treatment of soft tissue contusion: include injection of antibiotics, take some pain relieving Western medicine, can receive timely
Curative effect, but dampen after drug effect, be prone to pain, treatment to be used for multiple times, make contusion surface leave melanin scar.Can also
Use Chinese medicine just can have certain reducing swelling and alleviating pain effect after the drug of topical application of affected part, but mostly be all difficult to overcome black vestige after recovery from illness.
Summary of the invention
In order to after overcoming Western medicine or general treatment by Chinese herbs soft tissue contusion to recover slowly and treat, contusion surface stays black
The shortcoming of pigment trace, a kind of externally-used embrocation of the present invention, by smearing affected part, the function of antiinflammatory, stop-pass, recovery can be obtained,
Importantly contusion surface not scar, melanin vestige after recovery from illness.
Dampen with Chinese medicine viewpoint analysis human body soft tissue, belong to external force and attack caused blockage of main and collateral channels, QI-blood circulation not freely,
Should with dredge the meridian passage, promoting flow of QI and blood, dispel the wind the medicine partner treatment drawn out pus by applying a plaster to the affected part.A kind of topical agent treating soft tissue contusion makes
Method solution problem is adopted the technical scheme that to carry out by below step: raw materials quality part ratio one, used: Radix Notoginseng 10
Part, Radix Dipsaci 12 parts, Camphora 7 parts, Periostracum Serpentis 10 parts, 13 parts of the Radix Rehmanniae, Flos Lonicerae 13 parts, Radix Et Rhizoma Rhei 12 parts, Fructus Trichosanthis 12 parts, Exocarpium Benincasae 12
Part, Radix Isatidis 12 parts, 10 parts of Semen Persicae, ethanol 50 parts；Two, by Radix Dipsaci 12 parts, Periostracum Serpentis 10 parts, 13 parts of the Radix Rehmanniae, Flos Lonicerae 13 parts, big
Yellow 12 parts, Fructus Trichosanthis 12 parts, Exocarpium Benincasae 12 parts, 10 parts of Semen Persicae, Radix Isatidis 12 parts and one liter of clear water cross leaching after decocting 30 ~ 50 minutes
Medicinal liquid；Three, the medicinal liquid filtered is carried out further distillation and concentration to dilute thick mass；Four, by the dilute thick mass of distillation gained
Reduce temperature and move to hermetically drying case to 10 DEG C ~ 25 DEG C temperature, use external desiccant after being dried, to obtain yellow black and do
Dry Bulk drug；Five, together with the Bulk drug of dried gained and Camphora 7 parts, it is ground into mixed powder；Six, by Radix Notoginseng 10
Part smashs into Radix Notoginseng medicine mud to pieces；Seven, Radix Notoginseng medicine mud is added together with mixed powder 50 parts of ethanol quickly stir after bottle
Seal.
Medicine material property of medicine effect that the manufacture method of a kind of topical agent treating soft tissue contusion is used is as follows: three
Seven is outer for congestive edema mass formed by blood stasis such as traumatic injury congestion, traumatic hemorrhage；Radix Notoginseng also can prevent for various hyperlipidemia, regulation menstruation, cerebral infarction, brain
The symptoms such as blood supply insufficiency.Effect of Radix Dipsaci is reuniting the fractured tendons and bones, invigorating the liver and kidney, blood circulation regulating, and the effect of Radix Dipsaci is to control aching pain in waist and back, leukorrhagia,
Seminal emission, the foot and knee being feeble.Camphora be the root of canella Camphor tree, dry, branch, leaf through the refined granular substance of distillation, external removes
Wet parasite killing, warming and odynolysis, have one's ideas straightened out and ward off dirty effect.Periostracum Serpentis salty in the mouth, sweet, property is put down；Having expelling wind for relieving convulsion, detoxifying and relieving itching, improving eyesight is moved back
Effect of nebula;Cure mainly infantile convulsion epilepsy, cornea cataracta, sore throat acute throat trouble, aphtha, swelling of the gum, carbuncle furunculosis, scrofula malignant boil, rubella pruritus,
Leprosy, burn and scald.Radix Rehmanniae clearing away heat and promoting production of body fluid, removing heat from blood, hemostasis；For consumption of YIN caused by febrile disease, crimson tongue excessive thirst, send out speckle dermexanthesis, spit blood, epistaxis,
Laryngopharynx swelling and pain.Flos Lonicerae can dispelling wind-heat, be also apt to removing summer-heat blood poison, for various febrile diseases, such as fever of the body, dermexanthesis, send out speckle, pyretic toxicity
Carbuncle sore, laryngopharynx swelling and pain etc. are demonstrate,proved, and equal effect is notable.Radix Et Rhizoma Rhei have the strongest anti-infectious function, defying age antioxidation, can
The merits such as regulation immunity, antiinflammatory, refrigeration function, resisting pathogenic microbes effect, blood fat reducing, anastalsis, anti-stomach and duodenum are routed
Effect.The major function of Fructus Trichosanthis is removing heat-phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturizes laxation, detumescence and apocenosis.Fructus Trichosanthis has expansion to cardiovascular system
Zhang Zuoyong, resist myocardial ischemia, improve the effects such as microcirculation.Exocarpium Benincasae have delicate fragrance rise dissipate, inducing diuresis to remove edema, have summer heat relieving and dampness eliminating,
Spleen invigorating yang invigorating, effect of eliminating stasis to stop pain, it addition, Exocarpium Benincasae also has certain refrigerant, bleaching, effect of skin whitening.Semen Persicae energy
Blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, relieving cough and asthma；For amenorrhea, dysmenorrhea, abdominal mass mass in the abdomen, injury from falling down, dryness of the intestine constipation.Radix Isatidis
Effect mainly has heat clearing away with effect, removing toxic substances, removing heat from blood. control influenza, and epidemic encephalitis, encephalitis b, pneumonia, erysipelas, pyretic toxicity sends out speckle, and coma tells nosebleed,
Pharyngeal swelling, mumps, acute catarrhal conjunctivitis, skin ulcer rash, crimson tongue is purple dark, sore throat, rotten larynx etc..
A kind of treat soft tissue contusion the topical agent manufacture method beneficial effect of the invention be: one is treated soft tissue and is frustrated
The manufacture method of the topical agent of wound, by dampening with Chinese medicine viewpoint analysis soft tissue contusion, belongs to external force and attacks caused meridians
Obstructed, QI-blood circulation is smooth, takes to coordinate with dredge the meridian passage, promoting flow of QI and blood, the medicine drawn out pus by applying a plaster to the affected part that dispels the wind, is decocted by high temperature molten
Solution, distillation and concentration, cold drying, ethanol secondary solvent dissolve, and are fabricated to be prone to the outer topical agent being coated with and using, and detumescence is only
Effect bitterly is obvious, and does not stay melanin cicatrix after wound site recovery from illness.
Detailed description of the invention
Below in conjunction with embodiment, a kind of topical agent manufacture method treating soft tissue contusion is further described.
As a example by making a bottled medication amount, a kind of topical agent manufacture method of soft tissue contusion for the treatment of is by following
Making step is carried out: one, raw materials quality used: Radix Notoginseng 10 grams, Radix Dipsaci 12 grams, Camphora 7 grams, Periostracum Serpentis 10 grams, 13 grams of the Radix Rehmanniae, gold
Flos Lonicerae 13 grams, Radix Et Rhizoma Rhei 12 grams, Fructus Trichosanthis 12 grams, Exocarpium Benincasae 12 grams, Radix Isatidis 12 grams, 10 grams of Semen Persicae, ethanol 50 grams；Two, by Radix Dipsaci
12 grams, Periostracum Serpentis 10 grams, 13 grams of the Radix Rehmanniae, Flos Lonicerae 13 grams, Radix Et Rhizoma Rhei 12 grams, Fructus Trichosanthis 12 grams, Exocarpium Benincasae 12 grams, 10 grams of Semen Persicae, plate blue
Root 12 grams and one liter of clear water decoct 30 ~ 50 minutes after filtering extracting liquid；Three, the medicinal liquid filtered further is distilled dense
It is reduced to dilute thick mass；Four, the dilute thick mass of distillation gained is reduced temperature and moves to hermetically drying case to 10 DEG C ~ 25 DEG C temperature,
External desiccant is used to obtain, after being dried, the Bulk drug that yellow black is dried；Five, by the Bulk drug of dried gained with
Camphora 7 grams is ground into mixed powder together；Six, Radix Notoginseng 10 grams is smashed into pieces Radix Notoginseng medicine mud；Seven, by Radix Notoginseng medicine mud and mixed powder
Add bottling after quickly stirring in 50 grams of ethanol together to seal.
A kind of topical agent made by topical agent manufacture method treating soft tissue contusion, effect of reducing swelling and alleviating pain
Powerful, it is coated with outside the soft tissue contusion patient that 35 example traumatic injury cause and uses checking, effective percentage 100%.The external of this medicine
Time also can be better simultaneously with the use of for oral administration or injection of antibiotics, cure rate 100%, most importantly do not stay black after recovery from illness
Pigment cicatrix.
Claims (1)
1. treat a topical agent manufacture method for soft tissue contusion, it is characterized in that carrying out by below step: one, used
Raw materials quality part compare: Radix Notoginseng 10 parts, Radix Dipsaci 12 parts, Camphora 7 parts, Periostracum Serpentis 10 parts, 13 parts of the Radix Rehmanniae, Flos Lonicerae 13 parts, Radix Et Rhizoma Rhei 12 parts,
Fructus Trichosanthis 12 parts, Exocarpium Benincasae 12 parts, Radix Isatidis 12 parts, 10 parts of Semen Persicae, ethanol 50 parts；Two, by Radix Dipsaci 12 parts, Periostracum Serpentis 10 parts, the Radix Rehmanniae
13 parts, Flos Lonicerae 13 parts, Radix Et Rhizoma Rhei 12 parts, Fructus Trichosanthis 12 parts, Exocarpium Benincasae 12 parts, 10 parts of Semen Persicae, Radix Isatidis 12 parts and one liter of clear water are decocted
Boil filtering extracting liquid after 30 ~ 50 minutes；Three, the medicinal liquid filtered is carried out further distillation and concentration to dilute thick mass；Four, will
The dilute thick mass of distillation gained reduces temperature and moves to hermetically drying case to 10 DEG C ~ 25 DEG C temperature, uses external desiccant to carry out
Obtain the Bulk drug that yellow black is dried after drying；Five, mixed by being ground into together with the Bulk drug of dried gained and Camphora 7 parts
Close medicated powder；Six, Radix Notoginseng 10 parts is smashed into pieces Radix Notoginseng medicine mud；Seven, Radix Notoginseng medicine mud is added in 50 parts of ethanol together with mixed powder
After quickly stirring, bottling seals.
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