CN105832941A

CN105832941A - External-use ointment for treating tenosynovitis and preparation method thereof

Info

Publication number: CN105832941A
Application number: CN201610384520.6A
Authority: CN
Inventors: 温红卫
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-06-02
Filing date: 2016-06-02
Publication date: 2016-08-10

Abstract

The invention provides an external-use ointment for treating tenosynovitis and a preparation method thereof according to the pathogenesis of the tenosynovitis and aims to solve the problems that current medicine for treating the tenosynovitis is poor in curative effect, long in treatment course, easy in relapse, high in toxic and side effects, poor in pertinence and efficiency, low in safety, and the like. The external-use ointment is prepared by, by weight, 35-62 parts of raw radix aconiti, 6-15 parts of raw radix aconiti agrestis, 7-13 parts of gardenia jasminoides, 8-15 parts of incised notopterygium, 16-25 parts of taraxacum mongolicum, 14-28 parts of asarum, 6-12 parts of resina draconis, 17-26 parts of olibanum, 21-36 part of myrrh, 41-65 parts of caulis spatholobi, 22-36 parts of carthamus tinctorious, 36-43 parts of angelica sinensis and 8-23 parts of radix paeoniae rubra. The external-use ointment has the advantages that the 13 unique and carefully-selected traditional Chinese medicine raw materials of the external-use ointment are scientifically combined to achieve synergic and complementary effects, and the tenosynovitis is fundamentally improved and treated radically.

Description

A kind of externally-applied ointment varnish treating tenosynovitis and preparation method thereof

Technical field

The invention belongs to medical product technical field, a kind of for externally-applied ointment varnish treating tenosynovitis and preparation method thereof.

Background technology

Tenosynovitis is a kind of inflammation that flesh wild goose or flesh are good for surrounding tissue.There are the positions such as wrist, finger, shoulder in common affected part.Flesh is strong is a branch of link muscle and skeleton, the procerus muscle tendinitis diagram dimensional tissue of the pressure that conduction muscle produces.Flesh is good for has the resistance to function by bending, stretching and distorting.But working as fatigue, when fiber tearing or other damages, flesh is strong can inflammation.If the constantly motion in joint makes damage develop further, pain can clearly or increase the weight of.Tenosynovitis patient often has the symptoms such as pain in various degree, numbness, stiff, swelling, affected arthroncus, even snap, joint movement disorder at joint.Drastically influence normal activity and the quality of the life of patient.

At present, some common method for the treatment of for tenosynovitis include operative treatment and Drug therapy two kinds on the market.Operation or enclosed type treatment wound are big, and painful big, convalescent period is long.Mostly being some oral anti-inflammation analgesics in Drug therapy, these medicines not only effect is limited, function singleness, and is not directed to focus, uses the cycle long.Oral drugs also can have intense stimulus to gastrointestinal tract, and toxic and side effects is big, easily bounce-back, poor stability, thus does not reaches the purpose of safety thoroughly cure diseases, brings the biggest misery to patient.

Along with the progress of society, increasing people invest the sight for the treatment of disease in external application Chinese medicine class safe drugs natural, that have no side effect.Therefore, in order to effect a radical cure tenosynovitis, alleviate slight illness, develop and develop specific aim prepared by a kind of natural Chinese medicine and ageing strong, toxic and side effects is little, safety good, external application composition of medicine evident in efficacy is the most necessary.

Summary of the invention

It is an object of the invention to for current tenosynovitis medicine weak curative effect, use the cycle long, easily bounce-back, toxic and side effects is relatively big, specific aim and ageing strong, the problem such as safety is low, the pathogeny of conjoint tendon vaginitis, it is provided that a kind of for topical compositions ointment varnish treating tenosynovitis and preparation method thereof.

The present invention realizes above-mentioned purpose and the technical scheme is that a kind of externally-applied ointment varnish treating tenosynovitis, it is made up of following raw material according to parts by weight: Radix Aconiti 35-62 part, Radix Aconiti Kusnezoffii 6-15 part, Fructus Gardeniae 7-13 part, Rhizoma Et Radix Notopterygii 8-15 part, Herba Taraxaci 16-25 part, Herba Asari 14-28 part, Sanguis Draxonis 6-12 part, Olibanum 17-26 part, Myrrha 21-36 part, Caulis Spatholobi 41-65 part, Flos Carthami 22-36 part, Radix Angelicae Sinensis 36-43 part and Radix Paeoniae Rubra 8-23 part.

Preferably, described a kind of externally-applied ointment varnish treating tenosynovitis, it is made up of following raw material according to parts by weight: Radix Aconiti 50 parts, Radix Aconiti Kusnezoffii 10 parts, Fructus Gardeniae 10 parts, Rhizoma Et Radix Notopterygii 10 parts, Herba Taraxaci 20 parts, Herba Asari 20 parts, Sanguis Draxonis 10 parts, Olibanum 20 parts, Myrrha 30 parts, Caulis Spatholobi 50 parts, 30 parts of Flos Carthami, Radix Angelicae Sinensis 37 parts and Radix Paeoniae Rubra 21 parts.

Preferably, described a kind of externally-applied ointment varnish treating tenosynovitis, it is made up of following raw material according to parts by weight: Radix Aconiti 38 parts, Radix Aconiti Kusnezoffii 12 parts, Fructus Gardeniae 13 parts, Rhizoma Et Radix Notopterygii 9 parts, Herba Taraxaci 17 parts, Herba Asari 18 parts, Sanguis Draxonis 6 parts, Olibanum 26 parts, Myrrha 36 parts, Caulis Spatholobi 62 parts, 35 parts of Flos Carthami, Radix Angelicae Sinensis 41 parts and Radix Paeoniae Rubra 15 parts.

Preferably, described a kind of externally-applied ointment varnish treating tenosynovitis, it is made up of following raw material according to parts by weight: Radix Aconiti 60 parts, Radix Aconiti Kusnezoffii 8 parts, Fructus Gardeniae 9 parts, Rhizoma Et Radix Notopterygii 13 parts, Herba Taraxaci 22 parts, Herba Asari 26 parts, Sanguis Draxonis 11 parts, Olibanum 18 parts, Myrrha 24 parts, Caulis Spatholobi 44 parts, 30 parts of Flos Carthami, Radix Angelicae Sinensis 39 parts and Radix Paeoniae Rubra 19 parts.

The preparation method of the externally-applied ointment varnish of described treatment tenosynovitis, comprises the following steps:

(1), choose above crude drug, clean, carry out respectively being crushed to 100-200 mesh after drying；

(2), weigh, according to above-mentioned parts by weight, the crude drug powder that step (1) prepares respectively, mix homogeneously is placed in microwave dryer, under conditions of volume of material in putting into microwave dryer accounts for the internal free space 1/2～3/5 of microwave dryer, regulation microwave power is 300～500W, carries out microwave treatment 60～120s；

(3), putting in boiling container by the crude drug after step (2) microwave treatment, after adding water to submerge, carry out soaking 30-120min in 35-45 DEG C, then, normal pressure boils 20-30min, by filtration treatment, obtains filtrate a and filtering residue a, standby；

(4), the filtering residue a of step (3) gained is added water to submerge, afterwards, add the ratio of cellulase 10-20U according to every gram of filtering residue a, under 40 ~ 45 DEG C of temperature conditionss, carry out enzymolysis 1-1.5h, afterwards, filter, obtain filtrate b and filtering residue b, standby；

(5), the filtering residue b of step (4) gained is added water to submerge, under the conditions of 50-65 DEG C, carry out extracting 30-60min, afterwards, filter, gained filtering residue is added flooding 1-2 time again, merging multiple times of filtration gained filtrate, obtain filtrate c, standby；

(6), step (3) gained filtrate a, step (4) gained filtrate b and step (5) gained filtrate c are merged, afterwards, it is carried out vacuum-concentrcted and becomes paste, the externally-applied ointment varnish of tenosynovitis must be treated.

Beneficial effects of the present invention

The selected 13 taste Chinese medicines that the present invention is unique are raw material, scientific compatibility, synergism between various raw materials, have complementary advantages, bring out the best in each other, fundamentally improve and effected a radical cure the slight illness of tenosynovitis.With Radix Aconiti, Radix Aconiti Kusnezoffii, Rhizoma Et Radix Notopterygii and Herba Asari as monarch drug in formula, there is dispeling the wind, win the effects such as wet, pain relieving；With Caulis Spatholobi, Flos Carthami, Olibanum, Myrrha, Radix Angelicae Sinensis and Radix Paeoniae Rubra as ministerial drug, have invigorate blood circulation, nourish blood, dispel the wind, the effect such as pain relieving；With Fructus Gardeniae and Herba Taraxaci as adjuvant drug, there is the effect such as removing heat from blood, detumescence；With antibacterial, invigorate blood circulation, the Sanguis Draxonis of blood stasis dispelling for making medicine, play coordinating the actions of various ingredients in a prescription, further enhance the effect of this formula treatment tenosynovitis.Said medicine presses monarch compatibility, each medicine synergism, finished product external used medicine specific aim and ageing percutaneous absorbtion degree is good, and treatment cycle is short by force, and drug effect is magical notable, has anti-inflammation and sterilization, the curative effects such as detumescence, blood circulation promoting and blood stasis dispelling, promoting the circulation of QI to relieve pain of dispeling the wind.Pain can be eliminated rapidly, be effectively improved affected part peri-musculotendinous tissue microcirculation, fundamentally cut off pathogenesis, repair tendon tissue, recover joint normal function, reach thoroughly to cure the purpose of tendinitis.

Meanwhile, Chinese medicine preparation is owing to selecting raw material green natural, and therefore, toxic and side effects is little, low cost, cure rate is high, and drug action is strong, pollution-free in production, security reliability is good, even if life-time service, also medicine will not produce the untoward reaction such as dependence, be not easy to bounce-back after drug withdrawal.The preparation method of medicine is simple and easy to control, and low cost is worthy to be popularized.

Wherein: Radix Aconiti, pungent, temperature.Return lung, spleen, kidney, bladder warp.Effectively containing multiple alkaloid in pharmaceutical component, there is the effects such as promoting the circulation of QI to relieve pain, expelling wind and removing dampness, warming kidney for dispelling cold.Can be used for the disease such as anemofrigid-damp arthralgia, arthralgia.Meanwhile, it also has antiinflammatory and expansion blood vessel function, and the outer used time can stimulate skin, then produce feeling of numbness, therefore can make the analgesics of some neuralgia and rheumatism, and effect is notable.

Radix Aconiti Kusnezoffii, pungent, bitter, heat；Very toxic.GUIXIN, liver,kidney,spleen warp.Alkaloid aconitine and hypaconitine in its composition have analgesia and antiinflammatory action, and Mucocutaneous sensory nerve ending also can produce stimulation, and the outer used time can be used for topical anesthesia, expelling wind and removing dampness, antalgic.

Fructus Gardeniae, bitter in the mouth, cold.Enter the heart, liver, lung, stomach warp.For pathopyretic ulcer, sprain the auxiliary curative effect that swollen and ache.

Rhizoma Et Radix Notopterygii, acrid in the mouth；Bitter；Warm in nature.There is the effects such as relieving exterior syndrome and dispelling cold, expelling wind and dampness, profit joint, pain relieving.

Herba Taraxaci, sweet, micro-hardship, cold.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Modern pharmacological research shows: Herba Taraxaci has stronger bactericidal action to pathogenic microorganisms such as staphylococcus aureus resistance bacterial strain, Hemolytic streptococcuss；Can also improve the immunologic function of human body, the polysaccharide in its composition can be obviously enhanced the cytotoxicity of human macrophages.

Herba Asari has expelling wind and cold, sensible pain relieving, effect of warming the lung to resolve fluid-retention.Volatile oil in Herba Asari has obvious CNS inhibition and analgesic activity, is the valuable pharmacological basis of the various slight illness such as treatment head general pain.Herba Asari volatile oil also has the most antipyretic, antibacterial, antiviral, anti-inflammatory efficacy.Its antibacterial effective ingredient is safrole, and multiple fungus such as Aspergillus flavus, Aspergillus niger, Candida albicans etc. are all had inhibitory action.

Effective pharmaceutical component in Sanguis Draxonis has inhibitory action in various degree for multiple pathomycetes such as trichophyton, trichophyton gypseum, oidium schoenleiniis.Can also blood circulation promoting and blood stasis dispelling, shorten plasma recalcification time, thus increase its blood coagulation and anastalsis.

Olibanum, arduous, temperature.Enter the heart, liver, spleen channel.There is the effects such as blood-activating and qi-promoting, analgesic therapy, detumescence and promoting granulation.For treating coagulation of QI-blood, trusted subordinate's pain, ulcerative carbuncle toxic swelling, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.

Myrrha, acrid in the mouth is bitter, and property is put down.GUIXIN, liver, spleen channel.There is scattered blood blood stasis removing, the effect of subduing swelling and relieving pain.

Caulis Spatholobi, bitter, sweet, temperature.Return liver, kidney channel.Have and enrich blood, invigorate blood circulation, dredging collateral.For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.Its effective pharmaceutical component can expand blood vessel, antiplatelet aggregation, and experimental arthritis is had significant curative effect.

Flos Carthami, warm in nature, acrid in the mouth, promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury.When ancients often have what blood in vivo, often add Flos Carthami tate.Available one day twice foot bath boiled by bundle, is suitable for various varicosis, peripheral neuritis, and blood circulation is bad, lower limb numbness or the congestion such as livid purple.

Radix Angelicae Sinensis, sweet in the mouth；Pungent；Bitter；Warm in nature, return liver；The heart；Spleen channel, its be mainly used in hematonic, invigorate blood circulation, regulating menstruation, pain relieving.Body's immunity, replenishing and activating blood, antibacterial, arteriosclerosis effect can also be regulated.

Radix Paeoniae Rubra, bitter, it is slightly cold.Return Liver Channel.There is the effects such as blood stasis removing, pain relieving, removing heat from blood, detumescence.

The externally-applied ointment varnish preparation method of the treatment tenosynovitis of the present invention is in preparation process, it is provided with the step that dried crude drug is carried out microwave treatment, pass through microwave treatment, material table layer can be made to burst, mechanism structure changes, possessed loose porous character, beneficially crude drug powder follow-up immersion, boil and in enzymolysis, leaching process more fully by effective pharmaceutical component therein activate, and discharge so that it is function effect is more notable.

The present invention is provided with the step of micro-fermentation for the filtering residue after soaking, boiling extraction, by micro-sweat, effective pharmaceutical component glucosides class material in crude drug can be hydrolyzed by mycetogenetic a large amount of β-glucosidases hydrolytic enzyme in a large number, make it be discharged in filtrate with free state, thus improve the extraction of crude drug and effective rate of utilization and effective being absorbed by the body of pharmaceutical component.Microwave treatment step before fermentation can also make crude drug particle surface possess loose and porous structure, improves fermentation efficiency.

Detailed description of the invention

A kind of externally-applied ointment varnish treating tenosynovitis, it is made up of following raw material according to parts by weight: Radix Aconiti 35-62 part, Radix Aconiti Kusnezoffii 6-15 part, Fructus Gardeniae 7-13 part, Rhizoma Et Radix Notopterygii 8-15 part, Herba Taraxaci 16-25 part, Herba Asari 14-28 part, Sanguis Draxonis 6-12 part, Olibanum 17-26 part, Myrrha 21-36 part, Caulis Spatholobi 41-65 part, Flos Carthami 22-36 part, Radix Angelicae Sinensis 36-43 part and Radix Paeoniae Rubra 8-23 part.

Embodiment 1 :

A kind of externally-applied ointment varnish treating tenosynovitis, it is made up of following raw material according to parts by weight: Radix Aconiti 50 parts, Radix Aconiti Kusnezoffii 10 parts, Fructus Gardeniae 10 parts, Rhizoma Et Radix Notopterygii 10 parts, Herba Taraxaci 20 parts, Herba Asari 20 parts, Sanguis Draxonis 10 parts, Olibanum 20 parts, Myrrha 30 parts, Caulis Spatholobi 50 parts, 30 parts of Flos Carthami, Radix Angelicae Sinensis 37 parts and Radix Paeoniae Rubra 21 parts.

(1), choose above crude drug, clean, carry out respectively being crushed to 200 mesh after drying；

(2), weigh, according to above-mentioned parts by weight, the crude drug powder that step (1) prepares respectively, mix homogeneously is placed in microwave dryer, under conditions of volume of material in putting into microwave dryer accounts for the internal free space 1/2 of microwave dryer, regulation microwave power is 500W, carries out microwave treatment 90s；

(3), putting in boiling container by the crude drug after step (2) microwave treatment, after adding water to submerge, carry out soaking 90min in 45 DEG C, then, normal pressure boils 30min, by filtration treatment, obtains filtrate a and filtering residue a, standby；

(4), the filtering residue a of step (3) gained is added water to submerge, afterwards, add the ratio of cellulase 20U according to every gram of filtering residue a, under 40 DEG C of temperature conditionss, carry out enzymolysis 1.5h, afterwards, filter, obtain filtrate b and filtering residue b, standby；

(5), the filtering residue b of step (4) gained is added water to submerge, under the conditions of 60 DEG C, carry out extracting 50min, afterwards, filter, gained filtering residue is added flooding 2 times again, merge multiple times of filtration gained filtrate, obtain filtrate c, standby；

Embodiment 2 :

A kind of externally-applied ointment varnish treating tenosynovitis, it is made up of following raw material according to parts by weight: Radix Aconiti 38 parts, Radix Aconiti Kusnezoffii 12 parts, Fructus Gardeniae 13 parts, Rhizoma Et Radix Notopterygii 9 parts, Herba Taraxaci 17 parts, Herba Asari 18 parts, Sanguis Draxonis 6 parts, Olibanum 26 parts, Myrrha 36 parts, Caulis Spatholobi 62 parts, 35 parts of Flos Carthami, Radix Angelicae Sinensis 41 parts and Radix Paeoniae Rubra 15 parts.

(1), choose above crude drug, clean, carry out respectively being crushed to 100 mesh after drying；

(2), weigh, according to above-mentioned parts by weight, the crude drug powder that step (1) prepares respectively, mix homogeneously is placed in microwave dryer, under conditions of volume of material in putting into microwave dryer accounts for the internal free space 3/5 of microwave dryer, regulation microwave power is 300W, carries out microwave treatment 120s；

(3), putting in boiling container by the crude drug after step (2) microwave treatment, after adding water to submerge, carry out soaking 120min in 35 DEG C, then, normal pressure boils 20min, by filtration treatment, obtains filtrate a and filtering residue a, standby；

(4), the filtering residue a of step (3) gained is added water to submerge, afterwards, add the ratio of cellulase 10U according to every gram of filtering residue a, under 45 DEG C of temperature conditionss, carry out enzymolysis 1h, afterwards, filter, obtain filtrate b and filtering residue b, standby；

(5), the filtering residue b of step (4) gained is added water to submerge, under the conditions of 50 DEG C, carry out extracting 60min, afterwards, filter, gained filtering residue is added flooding 1 time again, merge multiple times of filtration gained filtrate, obtain filtrate c, standby；

Embodiment 3 :

A kind of externally-applied ointment varnish treating tenosynovitis, it is made up of following raw material according to parts by weight: Radix Aconiti 60 parts, Radix Aconiti Kusnezoffii 8 parts, Fructus Gardeniae 9 parts, Rhizoma Et Radix Notopterygii 13 parts, Herba Taraxaci 22 parts, Herba Asari 26 parts, Sanguis Draxonis 11 parts, Olibanum 18 parts, Myrrha 24 parts, Caulis Spatholobi 44 parts, 30 parts of Flos Carthami, Radix Angelicae Sinensis 39 parts and Radix Paeoniae Rubra 19 parts.

(2), weigh, according to above-mentioned parts by weight, the crude drug powder that step (1) prepares respectively, mix homogeneously is placed in microwave dryer, under conditions of volume of material in putting into microwave dryer accounts for the internal free space 1/2 of microwave dryer, regulation microwave power is 400W, carries out microwave treatment 120s；

(3), putting in boiling container by the crude drug after step (2) microwave treatment, after adding water to submerge, carry out soaking 300min in 40 DEG C, then, normal pressure boils 25min, by filtration treatment, obtains filtrate a and filtering residue a, standby；

(4), the filtering residue a of step (3) gained is added water to submerge, afterwards, add the ratio of cellulase 15U according to every gram of filtering residue a, under 43 DEG C of temperature conditionss, carry out enzymolysis 1.2h, afterwards, filter, obtain filtrate b and filtering residue b, standby；

(5), the filtering residue b of step (4) gained is added water to submerge, under the conditions of 65 DEG C, carry out extracting 30min, afterwards, filter, gained filtering residue is added flooding 2 times again, merge multiple times of filtration gained filtrate, obtain filtrate c, standby；

Clinical trial

In order to preferably verify the curative effect of the present invention, the externally-applied ointment varnish treating tenosynovitis using the proportioning raw materials described in the embodiment of the present invention 1 to prepare carries out clinical observation research, further illustrates the present invention curative effect to treatment tenosynovitis.

Clinical data:

Statistic record is on record and patient's totally 200 example of using the externally-applied ointment varnish for the treatment of tenosynovitis that the present invention provides to carry out treating tenosynovitis, age distribution 18-60 year between；The joint recovery of patient after the externally-applied ointment varnish of the treatment tenosynovitis that the statistics use present invention provides.Result shows, wherein 173 example patients are after the externally-applied ointment varnish using the present invention, and transference cure, tenosynovitis is effected a radical cure, and for effective effect, accounts for 86.5%；Have 26 example patients use the present invention externally-applied ointment varnish after, remission, swelling, inflammation etc. be improved significantly, for effectively, account for 13%；Only 1 example patient is after the externally-applied ointment varnish using the present invention, and symptom is not improved, and accounts for 0.5%.

Clinical treatment model case:

Case 1: Zhang, female, 36 years old, right finesse tenosynovitis March, pastes 5 times, recovery from illness.

Case 2: Chen, man, 68 years old, right finesse tenosynovitis more than 3 years, plaster January, alleviate.

Case 3: Wang, female, 46 years old, right elbow tenosynovitis February, pastes 5 times, recovery from illness.

The foregoing is only presently preferred embodiments of the present invention, not with the present invention for limiting, all any amendment, equivalent and improvement made within the spirit and principles in the present invention, should be included within the scope of the present invention.

Claims

1. the externally-applied ointment varnish treating tenosynovitis, it is characterized in that, be made up of following raw material according to parts by weight: Radix Aconiti 35-62 part, Radix Aconiti Kusnezoffii 6-15 part, Fructus Gardeniae 7-13 part, Rhizoma Et Radix Notopterygii 8-15 part, Herba Taraxaci 16-25 part, Herba Asari 14-28 part, Sanguis Draxonis 6-12 part, Olibanum 17-26 part, Myrrha 21-36 part, Caulis Spatholobi 41-65 part, Flos Carthami 22-36 part, Radix Angelicae Sinensis 36-43 part and Radix Paeoniae Rubra 8-23 part.

A kind of externally-applied ointment varnish treating tenosynovitis, it is characterized in that, it is made up of following raw material according to parts by weight: Radix Aconiti 50 parts, Radix Aconiti Kusnezoffii 10 parts, Fructus Gardeniae 10 parts, Rhizoma Et Radix Notopterygii 10 parts, Herba Taraxaci 20 parts, Herba Asari 20 parts, Sanguis Draxonis 10 parts, Olibanum 20 parts, Myrrha 30 parts, Caulis Spatholobi 50 parts, 30 parts of Flos Carthami, Radix Angelicae Sinensis 37 parts and Radix Paeoniae Rubra 21 parts.

A kind of externally-applied ointment varnish treating tenosynovitis, it is characterized in that, it is made up of following raw material according to parts by weight: Radix Aconiti 38 parts, Radix Aconiti Kusnezoffii 12 parts, Fructus Gardeniae 13 parts, Rhizoma Et Radix Notopterygii 9 parts, Herba Taraxaci 17 parts, Herba Asari 18 parts, Sanguis Draxonis 6 parts, Olibanum 26 parts, Myrrha 36 parts, Caulis Spatholobi 62 parts, 35 parts of Flos Carthami, Radix Angelicae Sinensis 41 parts and Radix Paeoniae Rubra 15 parts.

A kind of externally-applied ointment varnish treating tenosynovitis, it is characterized in that, it is made up of following raw material according to parts by weight: Radix Aconiti 60 parts, Radix Aconiti Kusnezoffii 8 parts, Fructus Gardeniae 9 parts, Rhizoma Et Radix Notopterygii 13 parts, Herba Taraxaci 22 parts, Herba Asari 26 parts, Sanguis Draxonis 11 parts, Olibanum 18 parts, Myrrha 24 parts, Caulis Spatholobi 44 parts, 30 parts of Flos Carthami, Radix Angelicae Sinensis 39 parts and Radix Paeoniae Rubra 19 parts.

5. the preparation method of a kind of externally-applied ointment varnish treating tenosynovitis as described in any claim in claim 1-4, it is characterised in that comprise the following steps: