CN107998325A - Strong drug use in osteopathy water of a kind of quick penetration and preparation method thereof - Google Patents

Strong drug use in osteopathy water of a kind of quick penetration and preparation method thereof Download PDF

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Publication number
CN107998325A
CN107998325A CN201810094038.8A CN201810094038A CN107998325A CN 107998325 A CN107998325 A CN 107998325A CN 201810094038 A CN201810094038 A CN 201810094038A CN 107998325 A CN107998325 A CN 107998325A
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liquid
water
gained
root
osteopathy
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张志良
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
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Abstract

The present invention relates to Medicines technical field, and in particular to strong drug use in osteopathy water of a kind of quick penetration and preparation method thereof；It is made of following raw material：Elder, hempleaf groundsel herb, cajan leaf, teasel root, cairo morningglory root or leaf, radix aconiti agrestis, monkshood, Angelica sinensis, asarum, fraxetin, pepper, chlorophyll, atoleine, galangal, Soil unit, chlorpheniramine, Li Kaduoyin, mannitol, menthol, camphor, rhizoma typhonii, frankincense, myrrh, notopterygium root, levisticum, lopseed, lycopodium calvatum, geranium wilfordii, climbing entada, safflower, reticulate millettia, giant knotweed, Morinda officinalis, Herba Epimedii, semen brassicae, pig label grass, mountain Changshan, brill earthworm, the root of bidentate achyranthes and the achene of Siberian cocklebur；Liquid medicine prepared by the present invention has the function of to soften spur well, the soft tissue of damage is repaired rapidly, moreover it is possible to quickly repairs nerve cell, osteocyte and muscle cell；Also there is good therapeutic effect to symptoms such as rheumatism, scapulohumeral periarthritis, cervical spondylosis, waist dish outstanding, gonitis and courbatures.

Description

Strong drug use in osteopathy water of a kind of quick penetration and preparation method thereof
Technical field
The present invention relates to Medicines technical field, and in particular to a kind of strong drug use in osteopathy water of quick penetration and its Preparation method.
Background technology
With advancing age, the cartilage in joint is gradually degenerated, cell elasticity reduction, Bones and joints unconsciously by Abrasion, especially the larger neck of activity, waist, knee joint, heel, damage articular cartilage no blood vessel supply nutrition when just It is difficult to repair, it is at this moment more vigorous in the peripheral blood circulation of articular cartilage, just occur that compensatory cartilage increases, this is bone The predecessor of matter hyperplasia.The cartilage of hyperplasia is again by calcification over time, and here it is osteoproliferation.It is a kind of natural aging phenomenon, General long spur means that the vertebra of this person enters the ageing step.
Spur, academic noun are bone wart, are not a medically appropriate nouns, because it is both non-fully made of bone, Also it is not sharp as pierced.Correct name medically should be bone wart.Spur is that wearing, breaking for cartilage is caused in joint because of various reasons It is bad, and facilitate repairing, hardening and the hyperplasia of bone in itself.Spur easily involves interphalangeal joint, knee joint, hip joint, cervical vertebra and chest Vertebra etc., is additionally found in acromioclavicular joint, remporomandibular joint, elbow joint etc..Spur is a kind of common disease, has intractable And the characteristics of recurrent.Spur can cause sciatica, disc herniation, spinal canal stenosis, degenerative arthritis, can when serious Cause people to walk and activity, seriously affect the quality of life of people.At present, doctor trained in Western medicine there is no effective medicine to this disease, Frequently with anti symptom treatment, such as pain when can take the medicine of some antipyretic-antalgics；When numb, B family vitamin class medicine can be selected；Joint Swelling has hydrops, and person can give the local extraction therapy such as hydrops or partial closure.It facts have proved that these treatment methods do not reach reason Think effect and palliative, the state of an illness is easy to recur.In addition ultraviolet therapy, massage, traction, acupuncture, massage, simply interim Local oedema and inflammation are eliminated, is tightly helped out to spur treatment.And the traditional Chinese medical science think spur be channels and collaterals obstruction qi depression to blood stasis, Caused by wind-cold damp pathogen.Cold-evil stagnates spasm, and damp evil adhesive aggregation is not changed, and causes the passages through which vital energy circulates such as waist-leg to be obstructed, and QI-blood circulation is not smooth or to fall servant outer Wound, damages passages through which vital energy circulates qi and blood, or because prolonged illness QI-blood circulation is not smooth, causes meridian qi and blood retardance obstructed and pathogenic.
Based on such a situation, there is provided a kind of customer for having significant curative effect for orthopaedic disease becomes this area skill with liquid medicine Art personnel's urgent problem to be solved！
The content of the invention
In view of the deficiencies of the prior art, the present invention provides a kind of strong drug use in osteopathy water of quick penetration and its preparation Method, prepared liquid medicine have the advantages that quick and penetration is strong, and can go directly lesion, to rheumatism, scapulohumeral periarthritis, cervical spondylosis, The symptoms such as waist dish outstanding, gonitis, courbature and strain have good therapeutic effect.
In order to achieve the above object, the present invention is achieved by the following technical programs：
A kind of strong drug use in osteopathy water of quick penetration, is prepared from the following raw materials in parts by weight：Elder 27-33g, Hempleaf groundsel herb 12-18g, cajan leaf 13-17g, teasel root 14-20g, cairo morningglory root or leaf 12-17g, radix aconiti agrestis 10-15g, monkshood 9-14g, Angelica sinensis 8- 14g, asarum 10-14g, fraxetin 13-18g, pepper 27-33g, chlorophyll 2-5g, atoleine 15-25ml, galangal 48- 55g, Soil unit 13-17g, chlorpheniramine 7-13g, Li Kaduoyin 26-32ml, mannitol 45-55ml, menthol 13-18g, camphor 12- 17g, rhizoma typhonii 13-17g, frankincense 28-33g, myrrh 27-32g, notopterygium root 12-16g, levisticum 13-16g, lopseed 28-34g, stretch Muscle grass 27-32g, geranium wilfordii 47-53g, climbing entada 13-17g, safflower 12-16g, reticulate millettia 12-18g, giant knotweed 14-17g, Morinda offcinalis How Its 28-33g, Herba Epimedii 27-32g, semen brassicae 12-17g, pig label grass 27-34g, mountain Changshan 12-16g, brill earthworm 13-17g, ox Knee 28-34g and achene of Siberian cocklebur 27-32g.
A kind of preparation method of the strong drug use in osteopathy water of quick penetration, comprises the following steps：
A, clean, dry：Will remove fraxetin, chlorophyll, atoleine, chlorpheniramine, Li Kaduoyin, mannitol, menthol, After starting material with water beyond camphor and frankincense cleans up, naturally dry；
B, extract：
(1) three, which shines three, boils extraction method：Asarum, monkshood, rhizoma typhonii are placed in the water of 300-500mL, and are 70- in temperature 25-35min is decocted under conditions of 85 DEG C, then filtered processing, 11 gained filter residue is placed at noon under sunlight when 13 Drying, so daily in triplicate, continues three days；The filtrate of gained three times is merged, gained is denoted as liquid a；
(2) wine immersion extraction method：Angelica sinensis, Soil unit and cairo morningglory root or leaf are placed in 1 jin of white wine and soak 7 days, then filtered place Reason, discards filter residue, gained liquid is denoted as liquid b；
(3) anima in the world is taken：Radix aconiti agrestis, reticulate millettia, Morinda officinalis, Herba Epimedii and semen brassicae are placed in sieve plate or are directly placed into Boiler, pot is interior plus the bed of material is crossed in water logging, distills 40-60min, then filtration treatment, takes 500mL filtrates, is irradiated under sunlight 50-70min, then sinks to and 40-50h is soaked in deep well, and gained liquid is denoted as liquid c；
(4) distillation and extraction method：Earthworm will be bored, mountain Changshan and the achene of Siberian cocklebur be placed in temperature be 60-70 DEG C, volume 300- 40-50h is soaked in the water of 500mL, then through being cooked by slow fire 20-30min, then filtered processing, discards filter residue, gained liquid is denoted as Liquid d；
(5) water cooking and extraction method：By remaining herbal medicine immersion in the water that temperature is 60-70 DEG C, volume is 1000-1200mL 42-50h, after being then cooked by slow fire 20-30min, is then adjusted to intense fire and boils 30-40min, filtered to handle and discard filter residue, gained Liquid is denoted as liquid e；
C, ultrasonic mixing：Liquid a, liquid b, liquid c, liquid d and the liquid e of gained in step b are mixed evenly, Supernatant liquor 1000-1200mL is taken after staticly settling, then by chlorophyll, atoleine, chlorpheniramine, lidocaine, mannitol, Menthol and camphor are blended into 1000mL supernatant liquors, after ultrasonic mixing is uniform, obtain liquid medicine finished product；
D, sampling observation, packaging：The liquid medicine finished product of gained in step c is sealed up for safekeeping, then carries out sterilization treatment, and to liquid medicine Finished product is inspected by random samples, packaging and storage after sampling observation is qualified.
Preferably, the concentration of white wine is 62 ° in the step (2) in the step b.
Preferably, the power of ultrasonic mixing is 500-600W in the step c.
Preferably, the sterilization method in the step d uses sterilization by ultraviolet.
Preferably, the time that staticly settles in the step c is 10-20min.
Beneficial effect：
The present invention selects a variety of genuine Chinese medicines and Western medicine as raw material, and by different extracting methods, by different Chinese medicines Active ingredient fully extract, not only increase the utilization rate of raw material, and the spirit for taking the world is realized in extraction process The purpose of gas so that the drug effect of the liquid medicine prepared by the present invention is more preferable, more fierce.Prepared liquid medicine can act on epidermis, Can rapid osmotic skin, reach periosteum deep layer, have the function of to soften spur well, can rapidly to the soft tissue of damage into Row is repaired, moreover it is possible to quickly repairs nerve cell, osteocyte and muscle cell.Dash forward for rheumatism, scapulohumeral periarthritis, cervical spondylosis, Waist disc Go out, the symptom such as gonitis, courbature and strain also has good therapeutic effect.In addition, liquid medicine prepared by the present invention stops Pain and anti-inflammatory effects are also than more significant.Relieved pain with 3-5 seconds, the effect of 5-10min anti-inflammatory, detumescence, disperse accumulation liquid.In addition, Liquid medicine prepared by the present invention also has effects that dredging the channel, promoting blood circulation and stopping pain and antianaphylactic.
Embodiment
To make the purpose, technical scheme and advantage of the embodiment of the present invention clearer, below in conjunction with the embodiment of the present invention, Technical solution in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is the present invention one Divide embodiment, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not making All other embodiments obtained under the premise of creative work, belong to the scope of protection of the invention.
Embodiment 1：
A kind of strong drug use in osteopathy water of quick penetration, is prepared from the following raw materials in parts by weight：Elder 27g, return Soul grass 15g, cajan leaf 13g, teasel root 15g, cairo morningglory root or leaf 12g, radix aconiti agrestis 12g, monkshood 9g, Angelica sinensis 10g, asarum 10g, fraxetin 15g, Pepper 27g, chlorophyll 3g, atoleine 15ml, galangal 50g, Soil unit 13g, chlorpheniramine 10g, Li Kaduoyin 26ml, mannitol 50ml, menthol 13g, camphor 15g, rhizoma typhonii 13g, frankincense 30g, myrrh 27g, notopterygium root 14g, levisticum 13g, lopseed 30g, stretch It is muscle grass 27g, geranium wilfordii 50g, climbing entada 13g, safflower 14g, reticulate millettia 12g, giant knotweed 15g, Morinda officinalis 28g, Herba Epimedii 29g, white Mustard seed 12g, pig label grass 30g, mountain Changshan 12g, bore earthworm 15g, root of bidentate achyranthes 28g and achene of Siberian cocklebur 29g.
A kind of preparation method of the strong drug use in osteopathy water of quick penetration, comprises the following steps：
A, clean, dry：Will remove fraxetin, chlorophyll, atoleine, chlorpheniramine, Li Kaduoyin, mannitol, menthol, After starting material with water beyond camphor and frankincense cleans up, naturally dry；
B, extract：
(1) three, which shines three, boils extraction method：Asarum, monkshood, rhizoma typhonii are placed in the water of 300mL, and are 70 DEG C in temperature Under the conditions of decoct 25min, gained filter residue, 11 is placed under sunlight and dries at noon, so by then filtered processing when 13 Daily in triplicate, three days are continued；The filtrate of gained three times is merged, gained is denoted as liquid a；
(2) wine immersion extraction method：Angelica sinensis, Soil unit and cairo morningglory root or leaf are placed in 1 jin of white wine and soak 7 days, then filtered place Reason, discards filter residue, gained liquid is denoted as liquid b；
(3) anima in the world is taken：Radix aconiti agrestis, reticulate millettia, Morinda officinalis, Herba Epimedii and semen brassicae are placed in sieve plate or are directly placed into Boiler, pot is interior plus the bed of material is crossed in water logging, distills 40min, then filtration treatment, takes 500mL filtrates, is irradiated under sunlight 50min, then sinks to and 40h is soaked in deep well, and gained liquid is denoted as liquid c；
(4) distillation and extraction method：Earthworm, mountain Changshan and the achene of Siberian cocklebur will be bored to be placed in the water that temperature is 60 DEG C, volume is 300mL 40h is soaked, then through being cooked by slow fire 20min, then filtered processing, discards filter residue, gained liquid is denoted as liquid d；
(5) water cooking and extraction method：By remaining herbal medicine immersion in the water that temperature is 60 DEG C, volume is 1000mL 42h, Ran Houwen After fire boils 20min, then it is adjusted to intense fire and boils 30min, filtered to handle and discard filter residue, gained liquid is denoted as liquid e；
C, ultrasonic mixing：Liquid a, liquid b, liquid c, liquid d and the liquid e of gained in step b are mixed evenly, Supernatant liquor 1000mL is taken after staticly settling, then by chlorophyll, atoleine, chlorpheniramine, lidocaine, mannitol, peppermint Brain and camphor are blended into 1000mL supernatant liquors, after ultrasonic mixing is uniform, obtain liquid medicine finished product；
D, sampling observation, packaging：The liquid medicine finished product of gained in step c is sealed up for safekeeping, then carries out sterilization treatment, and to liquid medicine Finished product is inspected by random samples, packaging and storage after sampling observation is qualified.
Preferably, the power of ultrasonic mixing is 500W in the step c.
Preferably, the time that staticly settles in the step c is 10min.
1st, 50 scapulohumeral periarthritis patients are allowed to adhere to that (7 days are one using two courses for the treatment of using the liquid medicine prepared by embodiment 1 The course for the treatment of), then this 50 scapulohumeral periarthritis patients are paid a return visit, wherein 43 scapulohumeral periarthritis conditions of patients are clearly better, 3 scapulohumeral periarthritis Conditions of patients somewhat improves, and for 4 scapulohumeral periarthritis conditions of patients without improvement, effective percentage is 92%.
2nd, 50 patient with cervical Spondylopathy are allowed to adhere to that (7 days are one using two courses for the treatment of using the liquid medicine prepared by embodiment 1 The course for the treatment of), then this 50 patient with cervical Spondylopathy are paid a return visit, wherein 45 patient with cervical Spondylopathy's state of an illness are clearly better, 2 cervical spondylosiss Conditions of patients somewhat improves, and for 3 patient with cervical Spondylopathy's state of an illness without improvement, effective percentage is 94%.
3rd, 50 waist dish outstanding patients are allowed using the liquid medicine prepared by embodiment 1, adhere to (be within 7 days using two courses for the treatment of One course for the treatment of), then this 50 waist dish outstanding patients are paid a return visit, wherein 39 waist dish outstanding conditions of patients are substantially good Turn, 6 waist dish outstanding conditions of patients somewhat improve, and for 5 waist dish outstanding conditions of patients without improvement, effective percentage is 90%.
4th, 50 gonitis patients are allowed to adhere to that (7 days are one using two courses for the treatment of using the liquid medicine prepared by embodiment 1 A course for the treatment of), then this 50 gonitis patients are paid a return visit, wherein 44 gonitis conditions of patients are clearly better, 3 Gonitis conditions of patients somewhat improves, and for 3 gonitis conditions of patients without improvement, effective percentage is 94%.
Embodiment 2：
A kind of strong drug use in osteopathy water of quick penetration, is prepared from the following raw materials in parts by weight：Elder 30g, return Soul grass 12g, cajan leaf 15g, teasel root 14g, cairo morningglory root or leaf 15g, radix aconiti agrestis 10g, monkshood 10g, Angelica sinensis 8g, asarum 12g, fraxetin 13g, Pepper 30g, chlorophyll 2g, atoleine 20ml, galangal 48g, Soil unit 15g, chlorpheniramine 7g, Li Kaduoyin 28ml, mannitol 45ml, menthol 15g, camphor 12g, rhizoma typhonii 15g, frankincense 28g, myrrh 29g, notopterygium root 12g, levisticum 14g, lopseed 28g, stretch It is muscle grass 29g, geranium wilfordii 47g, climbing entada 15g, safflower 12g, reticulate millettia 15g, giant knotweed 14g, Morinda officinalis 30g, Herba Epimedii 27g, white Mustard seed 14g, pig label grass 27g, mountain Changshan 14g, bore earthworm 13g, root of bidentate achyranthes 30g and achene of Siberian cocklebur 27g.
A kind of preparation method of the strong drug use in osteopathy water of quick penetration, comprises the following steps：
A, clean, dry：Will remove fraxetin, chlorophyll, atoleine, chlorpheniramine, Li Kaduoyin, mannitol, menthol, After starting material with water beyond camphor and frankincense cleans up, naturally dry；
B, extract：
(1) three, which shines three, boils extraction method：Asarum, monkshood, rhizoma typhonii are placed in the water of 350mL, and are 75 DEG C in temperature Under the conditions of decoct 30min, gained filter residue, 11 is placed under sunlight and dries at noon, so by then filtered processing when 13 Daily in triplicate, three days are continued；The filtrate of gained three times is merged, gained is denoted as liquid a；
(2) wine immersion extraction method：Angelica sinensis, Soil unit and cairo morningglory root or leaf are placed in 1 jin of white wine and soak 7 days, then filtered place Reason, discards filter residue, gained liquid is denoted as liquid b；
(3) anima in the world is taken：Radix aconiti agrestis, reticulate millettia, Morinda officinalis, Herba Epimedii and semen brassicae are placed in sieve plate or are directly placed into Boiler, pot is interior plus the bed of material is crossed in water logging, distills 45min, then filtration treatment, takes 500mL filtrates, is irradiated under sunlight 55min, then sinks to and 45h is soaked in deep well, and gained liquid is denoted as liquid c；
(4) distillation and extraction method：Earthworm, mountain Changshan and the achene of Siberian cocklebur will be bored to be placed in the water that temperature is 65 DEG C, volume is 350mL 45h is soaked, then through being cooked by slow fire 25min, then filtered processing, discards filter residue, gained liquid is denoted as liquid d；
(5) water cooking and extraction method：By remaining herbal medicine immersion in the water that temperature is 65 DEG C, volume is 1100mL 45h, Ran Houwen After fire boils 25min, then it is adjusted to intense fire and boils 35min, filtered to handle and discard filter residue, gained liquid is denoted as liquid e；
C, ultrasonic mixing：Liquid a, liquid b, liquid c, liquid d and the liquid e of gained in step b are mixed evenly, Supernatant liquor 1100mL is taken after staticly settling, then by chlorophyll, atoleine, chlorpheniramine, lidocaine, mannitol, peppermint Brain and camphor are blended into 1000mL supernatant liquors, after ultrasonic mixing is uniform, obtain liquid medicine finished product；
D, sampling observation, packaging：The liquid medicine finished product of gained in step c is sealed up for safekeeping, then carries out sterilization treatment, and to liquid medicine Finished product is inspected by random samples, packaging and storage after sampling observation is qualified.
Preferably, the power of ultrasonic mixing is 550W in the step c.
Preferably, the time that staticly settles in the step c is 15min.
1st, 50 scapulohumeral periarthritis patients are allowed to adhere to that (7 days are one using two courses for the treatment of using the liquid medicine prepared by embodiment 2 The course for the treatment of), then this 50 scapulohumeral periarthritis patients are paid a return visit, wherein 41 scapulohumeral periarthritis conditions of patients are clearly better, 3 scapulohumeral periarthritis Conditions of patients somewhat improves, and for 6 scapulohumeral periarthritis conditions of patients without improvement, effective percentage is 88%.
2nd, 50 patient with cervical Spondylopathy are allowed to adhere to that (7 days are one using two courses for the treatment of using the liquid medicine prepared by embodiment 2 The course for the treatment of), then this 50 patient with cervical Spondylopathy are paid a return visit, wherein 42 patient with cervical Spondylopathy's state of an illness are clearly better, 4 cervical spondylosiss Conditions of patients somewhat improves, and for 4 patient with cervical Spondylopathy's state of an illness without improvement, effective percentage is 92%.
3rd, 50 waist dish outstanding patients are allowed using the liquid medicine prepared by embodiment 2, adhere to (be within 7 days using two courses for the treatment of One course for the treatment of), then this 50 waist dish outstanding patients are paid a return visit, wherein 40 waist dish outstanding conditions of patients are substantially good Turn, 4 waist dish outstanding conditions of patients somewhat improve, and for 6 waist dish outstanding conditions of patients without improvement, effective percentage is 88%.
4th, 50 gonitis patients are allowed to adhere to that (7 days are one using two courses for the treatment of using the liquid medicine prepared by embodiment 2 A course for the treatment of), then this 50 gonitis patients are paid a return visit, wherein 42 gonitis conditions of patients are clearly better, 3 Gonitis conditions of patients somewhat improves, and for 5 gonitis conditions of patients without improvement, effective percentage is 90%.
Embodiment 3：
A kind of strong drug use in osteopathy water of quick penetration, is prepared from the following raw materials in parts by weight：Elder 31g, return Soul grass 18g, cajan leaf 17g, teasel root 20g, cairo morningglory root or leaf 16g, radix aconiti agrestis 15g, monkshood 12g, Angelica sinensis 14g, asarum 13g, fraxetin It is 18g, pepper 31g, chlorophyll 5g, atoleine 23ml, galangal 55g, Soil unit 16g, chlorpheniramine 13g, Li Kaduoyin 30ml, sweet Reveal alcohol 55ml, menthol 17g, camphor 17g, rhizoma typhonii 16g, frankincense 33g, myrrh 30g, notopterygium root 16g, levisticum 15g, lopseed 34g, lycopodium calvatum 30g, geranium wilfordii 53g, climbing entada 16g, safflower 16g, reticulate millettia 17g, giant knotweed 17g, Morinda officinalis 31g, Herba Epimedii 32g, semen brassicae 15g, pig label grass 34g, mountain Changshan 15g, brill earthworm 17g, root of bidentate achyranthes 32g and achene of Siberian cocklebur 32g.
A kind of preparation method of the strong drug use in osteopathy water of quick penetration, comprises the following steps：
A, clean, dry：Will remove fraxetin, chlorophyll, atoleine, chlorpheniramine, Li Kaduoyin, mannitol, menthol, After starting material with water beyond camphor and frankincense cleans up, naturally dry；
B, extract：
(1) three, which shines three, boils extraction method：Asarum, monkshood, rhizoma typhonii are placed in the water of 450mL, and are 80 DEG C in temperature Under the conditions of decoct 32min, gained filter residue, 11 is placed under sunlight and dries at noon, so by then filtered processing when 13 Daily in triplicate, three days are continued；The filtrate of gained three times is merged, gained is denoted as liquid a；
(2) wine immersion extraction method：Angelica sinensis, Soil unit and cairo morningglory root or leaf are placed in 1 jin of white wine and soak 7 days, then filtered place Reason, discards filter residue, gained liquid is denoted as liquid b；
(3) anima in the world is taken：Radix aconiti agrestis, reticulate millettia, Morinda officinalis, Herba Epimedii and semen brassicae are placed in sieve plate or are directly placed into Boiler, pot is interior plus the bed of material is crossed in water logging, distills 55min, then filtration treatment, takes 500mL filtrates, is irradiated under sunlight 65min, then sinks to and 48h is soaked in deep well, and gained liquid is denoted as liquid c；
(4) distillation and extraction method：Earthworm, mountain Changshan and the achene of Siberian cocklebur will be bored to be placed in the water that temperature is 68 DEG C, volume is 450mL 48h is soaked, then through being cooked by slow fire 28min, then filtered processing, discards filter residue, gained liquid is denoted as liquid d；
(5) water cooking and extraction method：By remaining herbal medicine immersion in the water that temperature is 68 DEG C, volume is 1150mL 48h, Ran Houwen After fire boils 27min, then it is adjusted to intense fire and boils 38min, filtered to handle and discard filter residue, gained liquid is denoted as liquid e；
C, ultrasonic mixing：Liquid a, liquid b, liquid c, liquid d and the liquid e of gained in step b are mixed evenly, Supernatant liquor 1150mL is taken after staticly settling, then by chlorophyll, atoleine, chlorpheniramine, lidocaine, mannitol, peppermint Brain and camphor are blended into 1000mL supernatant liquors, after ultrasonic mixing is uniform, obtain liquid medicine finished product；
D, sampling observation, packaging：The liquid medicine finished product of gained in step c is sealed up for safekeeping, then carries out sterilization treatment, and to liquid medicine Finished product is inspected by random samples, packaging and storage after sampling observation is qualified.
Preferably, the power of ultrasonic mixing is 580W in the step c.
Preferably, the time that staticly settles in the step c is 18min.
1st, 50 scapulohumeral periarthritis patients are allowed to adhere to that (7 days are one using two courses for the treatment of using the liquid medicine prepared by embodiment 3 The course for the treatment of), then this 50 scapulohumeral periarthritis patients are paid a return visit, wherein 45 scapulohumeral periarthritis conditions of patients are clearly better, 3 scapulohumeral periarthritis Conditions of patients somewhat improves, and for 2 scapulohumeral periarthritis conditions of patients without improvement, effective percentage is 96%.
2nd, 50 patient with cervical Spondylopathy are allowed to adhere to that (7 days are one using two courses for the treatment of using the liquid medicine prepared by embodiment 3 The course for the treatment of), then this 50 patient with cervical Spondylopathy are paid a return visit, wherein 46 patient with cervical Spondylopathy's state of an illness are clearly better, 1 cervical spondylosis Conditions of patients somewhat improves, and for 3 patient with cervical Spondylopathy's state of an illness without improvement, effective percentage is 94%.
3rd, 50 waist dish outstanding patients are allowed using the liquid medicine prepared by embodiment 3, adhere to (be within 7 days using two courses for the treatment of One course for the treatment of), then this 50 waist dish outstanding patients are paid a return visit, wherein 43 waist dish outstanding conditions of patients are substantially good Turn, 2 waist dish outstanding conditions of patients somewhat improve, and for 5 waist dish outstanding conditions of patients without improvement, effective percentage is 90%.
4th, 50 gonitis patients are allowed to adhere to that (7 days are one using two courses for the treatment of using the liquid medicine prepared by embodiment 3 A course for the treatment of), then this 50 gonitis patients are paid a return visit, wherein 40 gonitis conditions of patients are clearly better, 6 Gonitis conditions of patients somewhat improves, and for 4 gonitis conditions of patients without improvement, effective percentage is 92%.
Embodiment 4：
A kind of strong drug use in osteopathy water of quick penetration, is prepared from the following raw materials in parts by weight：Elder 33g, return Soul grass 16g, cajan leaf 16g, teasel root 18g, cairo morningglory root or leaf 17g, radix aconiti agrestis 13g, monkshood 14g, Angelica sinensis 12g, asarum 14g, fraxetin It is 16g, pepper 33g, chlorophyll 4g, atoleine 25ml, galangal 53g, Soil unit 17g, chlorpheniramine 11g, Li Kaduoyin 32ml, sweet Reveal alcohol 52ml, menthol 18g, camphor 16g, rhizoma typhonii 17g, frankincense 31g, myrrh 32g, notopterygium root 15g, levisticum 16g, lopseed 32g, lycopodium calvatum 32g, geranium wilfordii 51g, climbing entada 17g, safflower 15g, reticulate millettia 18g, giant knotweed 16g, Morinda officinalis 33g, Herba Epimedii 30g, semen brassicae 17g, pig label grass 32g, mountain Changshan 16g, brill earthworm 16g, root of bidentate achyranthes 34g and achene of Siberian cocklebur 30g.
A kind of preparation method of the strong drug use in osteopathy water of quick penetration, comprises the following steps：
A, clean, dry：Will remove fraxetin, chlorophyll, atoleine, chlorpheniramine, Li Kaduoyin, mannitol, menthol, After starting material with water beyond camphor and frankincense cleans up, naturally dry；
B, extract：
(1) three, which shines three, boils extraction method：Asarum, monkshood, rhizoma typhonii are placed in the water of 500mL, and are 85 DEG C in temperature Under the conditions of decoct 35min, gained filter residue, 11 is placed under sunlight and dries at noon, so by then filtered processing when 13 Daily in triplicate, three days are continued；The filtrate of gained three times is merged, gained is denoted as liquid a；
(2) wine immersion extraction method：Angelica sinensis, Soil unit and cairo morningglory root or leaf are placed in 1 jin of white wine and soak 7 days, then filtered place Reason, discards filter residue, gained liquid is denoted as liquid b；
(3) anima in the world is taken：Radix aconiti agrestis, reticulate millettia, Morinda officinalis, Herba Epimedii and semen brassicae are placed in sieve plate or are directly placed into Boiler, pot is interior plus the bed of material is crossed in water logging, distills 60min, then filtration treatment, takes 500mL filtrates, is irradiated under sunlight 70min, then sinks to and 50h is soaked in deep well, and gained liquid is denoted as liquid c；
(4) distillation and extraction method：Earthworm, mountain Changshan and the achene of Siberian cocklebur will be bored to be placed in the water that temperature is 70 DEG C, volume is 500mL 50h is soaked, then through being cooked by slow fire 30min, then filtered processing, discards filter residue, gained liquid is denoted as liquid d；
(5) water cooking and extraction method：By remaining herbal medicine immersion in the water that temperature is 70 DEG C, volume is 1200mL 50h, Ran Houwen After fire boils 30min, then it is adjusted to intense fire and boils 40min, filtered to handle and discard filter residue, gained liquid is denoted as liquid e；
C, ultrasonic mixing：Liquid a, liquid b, liquid c, liquid d and the liquid e of gained in step b are mixed evenly, Supernatant liquor 1200mL is taken after staticly settling, then by chlorophyll, atoleine, chlorpheniramine, lidocaine, mannitol, peppermint Brain and camphor are blended into 1000mL supernatant liquors, after ultrasonic mixing is uniform, obtain liquid medicine finished product；
D, sampling observation, packaging：The liquid medicine finished product of gained in step c is sealed up for safekeeping, then carries out sterilization treatment, and to liquid medicine Finished product is inspected by random samples, packaging and storage after sampling observation is qualified.
Preferably, the power of ultrasonic mixing is 600W in the step c.
Preferably, the time that staticly settles in the step c is 20min.
1st, 50 scapulohumeral periarthritis patients are allowed to adhere to that (7 days are one using two courses for the treatment of using the liquid medicine prepared by embodiment 4 The course for the treatment of), then this 50 scapulohumeral periarthritis patients are paid a return visit, wherein 44 scapulohumeral periarthritis conditions of patients are clearly better, 3 scapulohumeral periarthritis Conditions of patients somewhat improves, and for 3 scapulohumeral periarthritis conditions of patients without improvement, effective percentage is 94%.
2nd, 50 patient with cervical Spondylopathy are allowed to adhere to that (7 days are one using two courses for the treatment of using the liquid medicine prepared by embodiment 4 The course for the treatment of), then this 50 patient with cervical Spondylopathy are paid a return visit, wherein 43 patient with cervical Spondylopathy's state of an illness are clearly better, 2 cervical spondylosiss Conditions of patients somewhat improves, and for 5 patient with cervical Spondylopathy's state of an illness without improvement, effective percentage is 90%.
3rd, 50 waist dish outstanding patients are allowed using the liquid medicine prepared by embodiment 4, adhere to (be within 7 days using two courses for the treatment of One course for the treatment of), then this 50 waist dish outstanding patients are paid a return visit, wherein 45 waist dish outstanding conditions of patients are substantially good Turn, 3 waist dish outstanding conditions of patients somewhat improve, and for 2 waist dish outstanding conditions of patients without improvement, effective percentage is 96%.
4th, 50 gonitis patients are allowed to adhere to that (7 days are one using two courses for the treatment of using the liquid medicine prepared by embodiment 4 A course for the treatment of), then this 50 gonitis patients are paid a return visit, wherein 44 gonitis conditions of patients are clearly better, 2 Gonitis conditions of patients somewhat improves, and for 4 gonitis conditions of patients without improvement, effective percentage is 92%.
It should be noted that herein, relational terms such as first and second and the like are used merely to a reality Body or operation are distinguished with another entity or operation, are deposited without necessarily requiring or implying between these entities or operation In any this actual relation or order.Moreover, term " comprising ", "comprising" or its any other variant are intended to Non-exclusive inclusion, so that process, method, article or equipment including a series of elements not only will including those Element, but also including other elements that are not explicitly listed, or further include as this process, method, article or equipment Intrinsic key element.In the absence of more restrictions, the key element limited by sentence "including a ...", it is not excluded that Also there are other identical element in process, method, article or equipment including the key element.
The above embodiments are merely illustrative of the technical solutions of the present invention, rather than its limitations；Although with reference to the foregoing embodiments The present invention is described in detail, it will be understood by those of ordinary skill in the art that：It still can be to foregoing each implementation Technical solution described in example is modified, or carries out equivalent substitution to which part technical characteristic；And these modification or Replace, the essence of appropriate technical solution is departed from the spirit and scope of various embodiments of the present invention technical solution.

Claims (6)

  1. A kind of 1. strong drug use in osteopathy water of quick penetration, it is characterised in that：It is prepared from the following raw materials in parts by weight：Synthetism Wooden 27-33g, hempleaf groundsel herb 12-18g, cajan leaf 13-17g, teasel root 14-20g, cairo morningglory root or leaf 12-17g, radix aconiti agrestis 10-15g, monkshood 9- 14g, Angelica sinensis 8-14g, asarum 10-14g, fraxetin 13-18g, pepper 27-33g, chlorophyll 2-5g, atoleine 15-25ml, Galangal 48-55g, Soil unit 13-17g, chlorpheniramine 7-13g, Li Kaduoyin 26-32ml, mannitol 45-55ml, menthol 13- It is 18g, camphor 12-17g, rhizoma typhonii 13-17g, frankincense 28-33g, myrrh 27-32g, notopterygium root 12-16g, levisticum 13-16g, deep Careless 28-34g, lycopodium calvatum 27-32g, geranium wilfordii 47-53g, climbing entada 13-17g, safflower 12-16g, reticulate millettia 12-18g, giant knotweed 14-17g, Morinda officinalis 28-33g, Herba Epimedii 27-32g, semen brassicae 12-17g, pig label grass 27-34g, mountain Changshan 12-16g, brill ground Imperial 13-17g, root of bidentate achyranthes 28-34g and achene of Siberian cocklebur 27-32g.
  2. A kind of 2. preparation method of the strong drug use in osteopathy water of quick penetration according to claim 1, it is characterised in that Comprise the following steps：
    A, clean, dry：Fraxetin, chlorophyll, atoleine, chlorpheniramine, Li Kaduoyin, mannitol, menthol, camphor will be removed After being cleaned up with the starting material with water beyond frankincense, naturally dry；
    B, extract：
    (1) three, which shines three, boils extraction method：Asarum, monkshood, rhizoma typhonii are placed in the water of 300-500mL, and are 70-85 DEG C in temperature Under conditions of decoct 25-35min, gained filter residue, 11 is placed under sunlight and dries at noon by then filtered processing when 13, So daily in triplicate, three days are continued；The filtrate of gained three times is merged, gained is denoted as liquid a；
    (2) wine immersion extraction method：Angelica sinensis, Soil unit and cairo morningglory root or leaf are placed in 1 jin of white wine and soaked 7 days, then filtered processing, is abandoned Filter residue is removed, gained liquid is denoted as liquid b；
    (3) anima in the world is taken：Radix aconiti agrestis, reticulate millettia, Morinda officinalis, Herba Epimedii and semen brassicae are placed in sieve plate or are directly placed into distillation Pot, pot is interior plus the bed of material is crossed in water logging, distills 40-60min, then filtration treatment, takes 500mL filtrates, irradiates 50- under sunlight 70min, then sinks to and 40-50h is soaked in deep well, and gained liquid is denoted as liquid c；
    (4) distillation and extraction method：Earthworm will be bored, mountain Changshan and the achene of Siberian cocklebur be placed in temperature be 60-70 DEG C, volume be 300-500mL's 40-50h is soaked in water, then through being cooked by slow fire 20-30min, then filtered processing, discards filter residue, gained liquid is denoted as liquid d；
    (5) water cooking and extraction method：By remaining herbal medicine immersion in the water that temperature is 60-70 DEG C, volume is 1000-1200mL 42- 50h, after being then cooked by slow fire 20-30min, is then adjusted to intense fire and boils 30-40min, filtered to handle and discard filter residue, gained liquid It is denoted as liquid e；
    C, ultrasonic mixing：Liquid a, liquid b, liquid c, liquid d and the liquid e of gained in step b are mixed evenly, stood Supernatant liquor 1000-1200mL is taken after precipitation, then by chlorophyll, atoleine, chlorpheniramine, lidocaine, mannitol, peppermint Brain and camphor are blended into 1000mL supernatant liquors, after ultrasonic mixing is uniform, obtain liquid medicine finished product；
    D, sampling observation, packaging：The liquid medicine finished product of gained in step c is sealed up for safekeeping, then carries out sterilization treatment, and to liquid medicine finished product Inspected by random samples, packaging and storage after sampling observation is qualified.
  3. A kind of 3. preparation method of the strong drug use in osteopathy water of quick penetration according to claim 2, it is characterised in that： The concentration of white wine is 62 ° in step (2) in the step b.
  4. A kind of 4. preparation method of the strong drug use in osteopathy water of quick penetration according to claim 2, it is characterised in that： The power of ultrasonic mixing is 500-600W in the step c.
  5. A kind of 5. preparation method of the strong drug use in osteopathy water of quick penetration according to claim 2, it is characterised in that： Sterilization method in the step d uses sterilization by ultraviolet.
  6. A kind of 6. preparation method of the strong drug use in osteopathy water of quick penetration according to claim 2, it is characterised in that： The time that staticly settles in the step c is 10-20min.
CN201810094038.8A 2018-01-31 2018-01-31 Strong drug use in osteopathy water of a kind of quick penetration and preparation method thereof Pending CN107998325A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101530583A (en) * 2008-03-10 2009-09-16 曲宏民 Composition and preparation method of thin paste for treating pain and numbness
CN105832941A (en) * 2016-06-02 2016-08-10 温红卫 External-use ointment for treating tenosynovitis and preparation method thereof
CN106434219A (en) * 2016-11-23 2017-02-22 贺州市杨晋记豆豉有限公司 Rhizoma polygonati health care wine and brewing method thereof
CN106620400A (en) * 2017-03-06 2017-05-10 李朝成 Wine drug for treating chronic pain damage
CN107095916A (en) * 2017-07-02 2017-08-29 陈首名 Treat external medicine composition of neck-shoulder pain, lumbago and leg pain and preparation method thereof and application method

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101530583A (en) * 2008-03-10 2009-09-16 曲宏民 Composition and preparation method of thin paste for treating pain and numbness
CN105832941A (en) * 2016-06-02 2016-08-10 温红卫 External-use ointment for treating tenosynovitis and preparation method thereof
CN106434219A (en) * 2016-11-23 2017-02-22 贺州市杨晋记豆豉有限公司 Rhizoma polygonati health care wine and brewing method thereof
CN106620400A (en) * 2017-03-06 2017-05-10 李朝成 Wine drug for treating chronic pain damage
CN107095916A (en) * 2017-07-02 2017-08-29 陈首名 Treat external medicine composition of neck-shoulder pain, lumbago and leg pain and preparation method thereof and application method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
卓廉佳等: "针灸结合中药熏蒸治疗颈肩背肌筋膜炎30例", 《中医药导报》 *
王海舒: "中药贴敷治疗颈肩腰腿痛105例", 《中医外治杂志》 *

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