CN106109591A - For treating the micro-powder of Chinese herbs agent that chicken Ankara is sick - Google Patents

For treating the micro-powder of Chinese herbs agent that chicken Ankara is sick Download PDF

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Publication number
CN106109591A
CN106109591A CN201610480838.4A CN201610480838A CN106109591A CN 106109591 A CN106109591 A CN 106109591A CN 201610480838 A CN201610480838 A CN 201610480838A CN 106109591 A CN106109591 A CN 106109591A
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parts
powder
micro
chinese herbs
herbs agent
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刘翠艳
李桂华
韩春杨
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Anhui Agricultural University AHAU
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Anhui Agricultural University AHAU
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)
    • A61K36/855Clerodendrum, e.g. glorybower
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
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  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Alternative & Traditional Medicine (AREA)
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  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of for treating the micro-powder of Chinese herbs agent that chicken Ankara is sick, be made up of by weight following components: Fructus Forsythiae 4~10 parts, Folium Isatidis 5~10 parts, Radix Isatidis 4~8 parts, Flos Lonicerae 5~11 parts, Radix Bupleuri 1~5 parts, Poria 1~5 parts, Ramulus Cinnamomi 1~5 parts and Radix Glycyrrhizae 1~5 parts.The micro-powder of Chinese herbs agent of the present invention uses pure Chinese herbal medicine composition prescription, ultra micro powder is made by superfine communication technique, medical material ingredient is readily absorbed by, can effectively antiviral, antiinflammatory, antipyretic-antalgic, can also excitating organism immunity, recover rapidly body function, chicken Ankara disease cure rate reached 80.25%;This micro-powder of Chinese herbs agent is oral formulations, can directly be administered with spice feeding patterns, easy to use, it addition, the preparation method of this micro-powder of Chinese herbs agent is simple, with low cost, is suitable to industrialized mass production.

Description

For treating the micro-powder of Chinese herbs agent that chicken Ankara is sick
Technical field
The present invention relates to a kind of Chinese medicine preparation, a kind of for treating the micro-powder of Chinese herbs that chicken Ankara is sick Agent.
Background technology
Chicken pericardial effusion-hepatitis syndrome is sick also known as Ankara, the multiple broiler being born in 3~6 week old.Also seen in meat kind Chicken and laying hen.Morbidity chicken group starts death more than 3 week old, and 4~5 week old reach peak, peak duration 4~8 days.The course of disease usual 8 ~15 days, mortality rate reaches 25%~75%.It is characterized in that falling down to the ground suddenly without obvious tendency, spirit is depressed, and some arranges yellow loose stool, Two lower limbs draw sky, dead in several minutes.Sick Cor Gigeriae Galli flesh is soft, and pericardium amasss the transudate of pale yellow transparent.Liver swelling, hyperemia, Quality becomes fragile, and color and luster is dimmed, and necrosis occurs.Primary disease can vertical transmission and horizontal transmission.Chicken Ankara is sick in China in recent years It is widely current, and M & M is the highest, cause bigger economic loss to poultry husbandry.
Chicken Ankara disease there is no effectively preventing measure.In actual production, frequently with antiviral drugs and antibacterials Use in conjunction carries out preventing and controlling, but poor effect.Therefore, with Traditional Chinese Medicine Anti virus, tranquilizing mind, antiinflammatory, protect the liver and protect kidney possibility It it is the sick more efficiently way in treatment chicken Ankara.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of for treating the micro-powder of Chinese herbs agent that chicken Ankara is sick.
The another one technical problem that the invention solves the problems that is to provide a kind of for treating the micro-powder of Chinese herbs that chicken Ankara is sick The preparation method of agent.
For for treating the micro-powder of Chinese herbs agent that chicken Ankara is sick, the technical solution used in the present invention is, by following components Composition by weight:
Fructus Forsythiae 4~10 parts, Folium Isatidis 5~10 parts, Radix Isatidis 4~8 parts, Flos Lonicerae 5~11 parts, Radix Bupleuri 1~5 parts, Poria 1~5 Part, Ramulus Cinnamomi 1~5 parts and Radix Glycyrrhizae 1~5 parts.
As preferably, above-mentioned micro-powder of Chinese herbs agent is made up of by weight following components:
Fructus Forsythiae 6 parts, Folium Isatidis 7 parts, Radix Isatidis 6 parts, Flos Lonicerae 7 parts, Radix Bupleuri 2 parts, 2 parts of Poria, Ramulus Cinnamomi 3 parts and 3 parts of Radix Glycyrrhizae.
For the preparation method for treating the sick micro-powder of Chinese herbs agent in chicken Ankara, the technical solution used in the present invention is, Comprise the following steps:
(1) tentatively pulverize: weigh medical material by formula, each medical material is respectively crushed into coarse powder, mixing;
(2) micronizing: step (1) mixed coarse powder is carried out micronizing, it is thus achieved that fineness is 500 mesh and above thin Powder, is described micro-powder of Chinese herbs agent.
The principle that the present invention treats chicken Ankara sick is: according to herbal pharmacology, in described Chinese medicine formula, Fructus Forsythiae, Folium Isatidis Leaf, Radix Isatidis, Flos Lonicerae, all for the cause of disease, have heat-clearing and toxic substances removing, anti-pestilence effect, are principal agent altogether;Radix Bupleuri heat-clearing and toxic substances removing, expelling pathogenic factors from muscles Bring down a fever yang invigorating, for accessory drugs;Poria is put down, spleen invigorating mind calming, promoting diuresis to eliminate damp pathogen, and Ramulus Cinnamomi is warm in nature, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, plays balance With assist the major-minor medicine property of medicine, protect the liver and protect kidney, the merit of heart tonifying diuresis, for adjuvant drug;In the sweet mitigation of Radix Glycyrrhizae, invigorating the spleen and replenishing QI, removing toxic substances of eliminating the phlegm, For making medicine.All medicines share, and play heat-clearing and toxic substances removing altogether, protect the liver kidney, the effect of diuretic liquid.
Modern pharmacological research shows, Flos Lonicerae, Fructus Forsythiae, Radix Isatidis, Folium Isatidis have stronger antibacterial, antiviral, antiinflammatory Hepatoprotective effect;Radix Bupleuri has the effects such as antipyretic, antiinflammatory, promotion immunologic function;Ramulus Cinnamomi, Poria all have antiinflammatory, diuresis, regulation body Immunity;The effects such as Radix Glycyrrhizae antiinflammatory, antiviral, protecting liver and detoxication and enhancing immunologic function.
Beneficial effects of the present invention:
Provide a kind of for treating sick micro-powder of Chinese herbs agent in chicken Ankara and preparation method thereof, during this micro-powder of Chinese herbs agent employing is pure Medical herbs composition prescription, makes ultra micro powder by superfine communication technique so that medical material ingredient is readily absorbed by, can be the most anti- Virus, antiinflammatory, antipyretic-antalgic, moreover it is possible to excitating organism immunity, recovers rapidly body function, reaches chicken Ankara disease cure rate 80.25%;This micro-powder of Chinese herbs agent is oral formulations, can directly be administered with spice feeding patterns, easy to use, it addition, this Chinese medicine is micro- The preparation method of powder is simple, with low cost, is suitable to industrialized mass production.
Detailed description of the invention
Embodiment 1
1, formula components
By weight, Fructus Forsythiae 4 parts, Folium Isatidis 10 parts, Radix Isatidis 8 parts, Flos Lonicerae 5 parts, Radix Bupleuri 1 part, 1 part of Poria, Ramulus Cinnamomi 1 part are taken And 1 part of Radix Glycyrrhizae.
2, preparation method
(1) tentatively pulverize: weigh medical material by above-mentioned formula proportion, each medical material is respectively crushed into coarse powder, mixing;
(2) micronizing: utilize super micron mill, is ground into 500 mesh fineness further by the mixed coarse powder of step (1) Fine powder, i.e. obtains the present embodiment for treating the micro-powder of Chinese herbs agent that chicken Ankara is sick.
3, mode is taken: oral.
4, clinical verification
Choosing clinical manifestation is heating, and spirit is depressed, and what appetite declined suffers from the sick chicken 1500 that chicken Ankara is sick, by above-mentioned preparation The micro-powder of Chinese herbs agent obtained is mixed in feedstuff by the percentage by weight of 2%, takes to sick chicken, every day 1 time, is used in conjunction 5 days, and result is common Curing 950, cure rate is 63.33%.
Embodiment 2
1, formula components
By weight, Fructus Forsythiae 6 parts, Folium Isatidis 7 parts, Radix Isatidis 6 parts, Flos Lonicerae 7 parts, Radix Bupleuri 2 parts, 2 parts of Poria, Ramulus Cinnamomi 3 parts are taken And 3 parts of Radix Glycyrrhizae.
2, preparation method (with embodiment 1)
3, mode is taken: oral.
4, clinical verification
Choosing clinical manifestation is heating, and spirit is depressed, and what appetite declined suffers from the sick chicken 2000 that chicken Ankara is sick, by above-mentioned preparation The micro-powder of Chinese herbs agent obtained is mixed in feedstuff by the percentage by weight of 2%, takes to sick chicken, every day 1 time, is used in conjunction 5 days, and result is common Curing 1650, cure rate is 80.25%.
Embodiment 3
1, formula components
By weight, take stick up repeatedly 10 parts, Folium Isatidis 5 parts, Radix Isatidis 4 parts, Flos Lonicerae 11 parts, Radix Bupleuri 5 parts, 5 parts of Poria, Ramulus Cinnamomi 5 parts and 5 parts of Radix Glycyrrhizae.
2, preparation method (with embodiment 1)
3, mode is taken: oral.
4, clinical verification
Choosing clinical manifestation is heating, and spirit is depressed, and what appetite declined suffers from the sick chicken 1100 that chicken Ankara is sick, by above-mentioned preparation The micro-powder of Chinese herbs agent obtained is mixed in feedstuff by the percentage by weight of 2%, takes to sick chicken, every day 1 time, is used in conjunction 5 days, and result is common Curing 745, cure rate is 67.73%.
Invention described above embodiment, is not intended that limiting the scope of the present invention.Any in the present invention Spirit and principle within amendment, equivalent and the improvement etc. made, should be included in the claim protection model of the present invention Within enclosing.

Claims (3)

1. for treating the micro-powder of Chinese herbs agent that chicken Ankara is sick, it is characterised in that be made up of by weight following components:
Fructus Forsythiae 4~10 parts, Folium Isatidis 5~10 parts, Radix Isatidis 4~8 parts, Flos Lonicerae 5~11 parts, Radix Bupleuri 1~5 parts, Poria 1~5 Part, Ramulus Cinnamomi 1~5 parts and Radix Glycyrrhizae 1~5 parts.
Micro-powder of Chinese herbs agent the most according to claim 1, it is characterised in that be made up of by weight following components:
Fructus Forsythiae 6 parts, Folium Isatidis 7 parts, Radix Isatidis 6 parts, Flos Lonicerae 7 parts, Radix Bupleuri 2 parts, 2 parts of Poria, Ramulus Cinnamomi 3 parts and 3 parts of Radix Glycyrrhizae.
3. the preparation method of micro-powder of Chinese herbs agent as claimed in claim 1, it is characterised in that comprise the following steps:
(1) tentatively pulverize: weigh medical material by formula, each medical material is respectively crushed into coarse powder, mixing;
(2) micronizing: step (1) mixed coarse powder is carried out micronizing, it is thus achieved that fineness is 500 mesh and above thin Powder, is described micro-powder of Chinese herbs agent.
CN201610480838.4A 2016-06-28 2016-06-28 For treating the micro-powder of Chinese herbs agent that chicken Ankara is sick Pending CN106109591A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106421725A (en) * 2016-11-30 2017-02-22 河南牧翔动物药业有限公司 Traditional Chinese medicine composition for preventing and treating poultry Ankara disease and preparation method thereof
CN107279574A (en) * 2017-07-25 2017-10-24 安徽华米生物科技有限公司 It is a kind of to be used to prevent feed of duck Ankara disease and preparation method thereof
CN107647166A (en) * 2017-09-30 2018-02-02 安徽麒麟正大饲料有限公司 It is a kind of to be used to prevent and treat 4% premix of broiler chicken Ankara disease and preparation method thereof
CN108478639A (en) * 2018-05-28 2018-09-04 安徽科技学院 Chinese medicine composition and its preparation method and application for treating/preventing poultry Ankara disease

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106421725A (en) * 2016-11-30 2017-02-22 河南牧翔动物药业有限公司 Traditional Chinese medicine composition for preventing and treating poultry Ankara disease and preparation method thereof
CN107279574A (en) * 2017-07-25 2017-10-24 安徽华米生物科技有限公司 It is a kind of to be used to prevent feed of duck Ankara disease and preparation method thereof
CN107647166A (en) * 2017-09-30 2018-02-02 安徽麒麟正大饲料有限公司 It is a kind of to be used to prevent and treat 4% premix of broiler chicken Ankara disease and preparation method thereof
CN108478639A (en) * 2018-05-28 2018-09-04 安徽科技学院 Chinese medicine composition and its preparation method and application for treating/preventing poultry Ankara disease
CN108478639B (en) * 2018-05-28 2020-11-10 安徽科技学院 Traditional Chinese medicine composition for treating/preventing poultry Ankara disease and preparation method and application thereof

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