CN106074286A - Skin protection plant essence aerosol with sun-proof white-skinned face function and preparation method thereof - Google Patents
Skin protection plant essence aerosol with sun-proof white-skinned face function and preparation method thereof Download PDFInfo
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- CN106074286A CN106074286A CN201610569190.8A CN201610569190A CN106074286A CN 106074286 A CN106074286 A CN 106074286A CN 201610569190 A CN201610569190 A CN 201610569190A CN 106074286 A CN106074286 A CN 106074286A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/046—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
Abstract
The present invention provides a kind of skin protection plant essence aerosol with sun-proof white-skinned face function and preparation method, belongs to skin care field.This aerosol in parts by weight, specifically includes that trehalose 20 30 parts, oligomerization hyaluronate sodium 0.4 0.6 parts, nicotiamide 5 15 parts, butanediol 40 60 parts, plant antiseptic agent NPS5 9 parts, 0.1 0.4 parts of essence, PEG 40 castor oil hydrogenated 23 parts, Aesculus chinensis Bunge extract 50 80 parts, Rhizoma Chuanxiong extract 50 80 parts, Radix Scutellariae extract 30 80 parts, Rhizoma Polygonati Odorati extract 60 100 parts, Ganoderma extract 10 30 parts, licorice root extract 10 30 parts, 10% potassium hydroxide solution 5 30 parts.The present invention also provides for the preparation method of a kind of skin protection plant essence aerosol with sun-proof white-skinned face function.This aerosol to prevent skin sunburn, tanned and tenderization skin and alleviate, eliminate chloasma, freckle and senile plaque have good effect.
Description
Technical field
The invention belongs to skin care field, be specifically related to a kind of skin protection plant essence aerosol with sun-proof white-skinned face function
And preparation method.
Background technology
Along with the progress of society, the raising of people's living standard, consumer is to self appearance and health requirements increasingly
High.The pigmentation etc. that day sunburn that born freckle, Exposure to Sunlight cause, life-time service cosmetics cause have impact on people face
Attractive in appearance.And in recent years, along with in nature, atmospheric ozone layer segment is destroyed, solar UV irradiates to be made human body skin
The harm become the most increasingly is subject to people's attention.The direct irradiation of ultraviolet can cause skin speckle, melanin deposition,
A series of skin problems such as dermatitis even skin carcinoma.
The product of existing sun-proof whitening is many containing chemical composition, hormone medicine etc., face skin is had stimulation and
Toxic and side effects, therapeutic effect is the most inconspicuous, and easily rebounds.And existing whitening sun protection product is cream mostly, use
Extremely inconvenience, also to smear a thick layer of, and impact perspires, if also preferably contaminating medicated clothing etc. after antiperspirant leaching.
Caused by cosmetics for special use refers to the cosmetics of drug containing, is the combination of D&C, is that medicine is to cosmetics
Infiltration.It is referred to as " quasi drug ", also known as " medicine part outer article " in Japan;It is referred to as OTC (over-in the U.S., Britain's part
The-ocunte drug) product, i.e. " nonprescription drugs ", including adding the skin-care product of medicine, skin protection and the nursing of hair
Product, cleaning agent for mouth cavity etc., the title medicine cosmetic also having.It is referred to as caused by cosmetics for special use in China, adds chemicals, particularly
Add China distinctive Chinese medicine, in addition to beautifying human body tenderization skin, have again effect of regulating body function concurrently, but require safety,
Nontoxic, have no side effect.
Summary of the invention
The invention aims to solve existing sun-proof Skin whitening care cosmetics and contain chemistry and hormone medicine to skin
There is stimulation, and great majority are the problems such as cream impact perspires, and a kind of skin protection plant with sun-proof white-skinned face function is provided
Elite aerosol and preparation method.
Present invention firstly provides a kind of skin protection plant essence aerosol with sun-proof white-skinned face function, according to parts by weight
Meter, including:
Deionized water 400-700 part, trehalose 20-30 part, oligomerization hyaluronate sodium 0.4-0.6 part, nicotiamide 5-15 part,
Butanediol 40-60 part, plant antiseptic agent NPS5-9 part, essence 0.1-0.4 part, Cremophor RH40 2-3 part, Aesculus chinensis Bunge carries
Take thing 50-80 part, Rhizoma Chuanxiong extract 50-80 part, Radix Scutellariae extract 30-80 part, Rhizoma Polygonati Odorati extract 60-100 part, Ganoderma extract
10-30 part, licorice root extract 10-30 part, 10% potassium hydroxide solution 5-30 part, distilled water 25-350 part.
Preferably, there is the skin protection plant essence aerosol of sun-proof white-skinned face function, in parts by weight, including: go
Ionized water 500-600 part, trehalose 22-28 part, oligomerization hyaluronate sodium 0.4-0.6 part, nicotiamide 7-12 part, butanediol 45-
55 parts, plant antiseptic agent NPS 6-8 part, essence 0.2-0.3 part, Cremophor RH40 2-3 part, Aesculus chinensis Bunge extract 60-
70 parts, Rhizoma Chuanxiong extract 60-70 part, Radix Scutellariae extract 50-70 part, Rhizoma Polygonati Odorati extract 80-90 part, Ganoderma extract 15-25 part,
Licorice root extract 15-25 part, 10% potassium hydroxide solution 8-20 part, distilled water 50-100 part.
Preferably, there is the skin protection plant essence aerosol of sun-proof white-skinned face function, in parts by weight, including: go
Ionized water 500 parts, trehalose 25 parts, oligomerization hyaluronate sodium 0.5 part, nicotiamide 9 parts, butanediol 50 parts, plant antiseptic agent NPS
7 parts, 0.25 part of essence, Cremophor RH40 2.5 parts, Aesculus chinensis Bunge extract 65 parts, Rhizoma Chuanxiong extract 65 parts, Radix Scutellariae extracts
Thing 60 parts, Rhizoma Polygonati Odorati extract 85 parts, Ganoderma extract 20 parts, licorice root extract 20 parts, 10% potassium hydroxide solution 15 parts, steams
Distilled water 75.75 parts.
The present invention also provides for the preparation method of a kind of skin protection plant essence aerosol with sun-proof white-skinned face function, including:
Step one: in reaction vessel, trehalose, oligomerization hyaluronate sodium and nicotiamide are dissolved in deionized water and stir
Dissolve, be warming up to 80-90 DEG C of reaction, obtain mixed solution I;
Step 2: temperature in reaction vessel is down to 40-50 DEG C, then in mixed solution I, addition butanediol, plant prevent
Rotten agent NPS, essence and Cremophor RH40 stirring, add 10% potassium hydroxide solution, obtain mixed solution II;
Step 3: temperature in reaction vessel is down to 30-40 DEG C, then adds Aesculus chinensis Bunge in mixed solution II and extracts
Thing, Rhizoma Chuanxiong extract, Radix Scutellariae extract, Rhizoma Polygonati Odorati extract, Ganoderma extract and licorice root extract stirring, add distillation
Water, obtains the skin protection plant essence aerosol with sun-proof white-skinned face function.
Preferably, the response time of described step one is 20min.
Preferably, the mixing time of described step 2 is 20-60min.
Preferably, the mixing time of described step 3 is 20-60min.
Beneficial effects of the present invention
The present invention provides a kind of skin protection plant essence aerosol with sun-proof white-skinned face function and preparation method, and this skin protection is planted
Thing elite aerosol selects the Chinese medicine ingredients of pure natural, wherein Aesculus chinensis Bunge extract, Rhizoma Chuanxiong extract, Radix Scutellariae extract and Rhizoma Polygonati Odorati
Extract can combine with cell, before cell damage, by skin produces in ultraviolet the ingredient draws of injury, reaches sun-proof
Purpose, and damaged cell can be repaired rapidly, block melanic synthesis, reduce the black speck growth of skin after shining, after there is solarization
The effect repaired;Ganoderma extract plays the effect brightened with speckle, and licorice root extract plays antibacterial, effect of antiinflammatory, this
The skin protection plant essence aerosol of invention all selects natural composition of releiving, little to skin irritation, the experiment proved that the present invention's
Aerosol to prevent skin sunburn, tanned and tenderization skin and alleviate, eliminate chloasma, freckle and senile plaque have good effect
Really, for prevention, the sun-proof and whitening of pigmentation spots.The raw material of the present invention is easy to get, and preparation method is simple, has good answering
Use prospect.
Detailed description of the invention
Present invention firstly provides a kind of skin protection plant essence aerosol with sun-proof white-skinned face function, according to parts by weight
Meter, including:
Deionized water 400-700 part, trehalose 20-30 part, oligomerization hyaluronate sodium 0.4-0.6 part, nicotiamide 5-15 part,
Butanediol 40-60 part, plant antiseptic agent NPS (polyhydric alcohol plant compound preservative) 5-9 part, essence 0.1-0.4 part, PEG-40 hydrogen
Changing Oleum Ricini 2-3 part, Aesculus chinensis Bunge extract 50-80 part, Rhizoma Chuanxiong extract 50-80 part, Radix Scutellariae extract 30-80 part, Rhizoma Polygonati Odorati carries
Take thing 60-100 part, Ganoderma extract 10-30 part, licorice root extract 10-30 part, 10% potassium hydroxide solution 5-30 part, steam
Distilled water 25-350 part.
Preferably, there is the skin protection plant essence aerosol of sun-proof white-skinned face function, in parts by weight, including: go
Ionized water 500-600 part, trehalose 22-28 part, oligomerization hyaluronate sodium 0.4-0.6 part, nicotiamide 7-12 part, butanediol 45-
55 parts, plant antiseptic agent NPS 6-8 part, essence 0.2-0.3 part, Cremophor RH40 2-3 part, Aesculus chinensis Bunge extract 60-
70 parts, Rhizoma Chuanxiong extract 60-70 part, Radix Scutellariae extract 50-70 part, Rhizoma Polygonati Odorati extract 80-90 part, Ganoderma extract 15-25 part,
Licorice root extract 15-25 part, 10% potassium hydroxide solution 8-20 part, distilled water 50-100 part.
It is further preferred that have the skin protection plant essence aerosol of sun-proof white-skinned face function, in parts by weight, including:
Deionized water 500 parts, trehalose 25 parts, oligomerization hyaluronate sodium 0.5 part, nicotiamide 9 parts, butanediol 50 parts, plant antiseptic agent
NPS 7 parts, 0.25 part of essence, Cremophor RH40 2.5 parts, Aesculus chinensis Bunge extract 65 parts, Rhizoma Chuanxiong extract 65 parts, Radix Scutellariae
Extract 60 parts, Rhizoma Polygonati Odorati extract 85 parts, Ganoderma extract 20 parts, licorice root extract 20 parts, 10% potassium hydroxide solution 15
Part, distilled water 75.75 parts.
According to the present invention, the pharmacological action of Chinese medicine of the present invention is as follows:
Oligomerization hyaluronate sodium: wetting agent, during high humidity, water suction is few, opens metabolic pathway, deep moisturizing, and emollient is good.
Nicotiamide: nutrient, whitening, suppression melanin produces, and prevents and treats eczema and pachylosis, nutrition skin.
Butanediol: wetting agent, moistening effect is good, and water absorption is fewer than glycerol, and during high humidity, skin beauty water texture is strong, clearly, clearly
Clean, lyotropy good, antifreeze.
Plant antiseptic agent NPS (polyhydric alcohol plant compound preservative): preservative, polyhydric alcohol plant composite anti-corrosive, low stimulation
Property.
Essence: deodorant tune, has colored natural scents, has cosmetic result simultaneously.
Cremophor RH40: solubilizing agent, solubilising Oil soluble materials, cleaning skin, stabilising system, safer.
10% potassium hydroxide solution: neutralize acid material, adjusts pH value.
Aesculus chinensis Bunge extract: activating skin, anti-aging, anti-ultraviolet.
Rhizoma Chuanxiong extract: wind, invigorate blood circulation, skin moistening, lipotropism overflow, hair care, defying age, sun-proof.
Radix Scutellariae extract: antibacterial, antiallergic, defying age, antipruritic, sun-proof.
Rhizoma Polygonati Odorati extract: skin protection, antibacterial, skin care, beauty treatment, defying age.
Ganoderma extract: defying age, crease-resistant, brighten, speckle, skin protection.
Licorice root extract: antibacterial, antiinflammatory, antiallergic, antiviral.
The present invention also provides for the preparation method of a kind of skin protection plant essence aerosol with sun-proof white-skinned face function, including:
Step one: in reaction vessel, trehalose, oligomerization hyaluronate sodium and nicotiamide are dissolved in deionized water and stir
Dissolving, be warming up to 80-90 DEG C of reaction, the described response time is preferably 20min, obtains mixed solution I;
Step 2: temperature in reaction vessel is down to 40-50 DEG C, then in mixed solution I, addition butanediol, plant prevent
Rotten agent NPS, essence and Cremophor RH40 stirring, add 10% potassium hydroxide solution, adjust pH to 5.0-6.0, obtain
Mixed solution II;Described mixing time is preferably 20-60min;
Step 3: temperature in reaction vessel is down to 30-40 DEG C, then adds Aesculus chinensis Bunge in mixed solution II and extracts
Thing, Rhizoma Chuanxiong extract, Radix Scutellariae extract, Rhizoma Polygonati Odorati extract, Ganoderma extract and licorice root extract stirring, add distillation
Water, obtains the skin protection plant essence aerosol with sun-proof white-skinned face function, and described mixing time is preferably 20-60min.
Form by the following examples, is described in further detail the foregoing of the present invention again, but should be by this
It is interpreted as that the scope of this bright above-mentioned theme is only limitted to Examples below, all technology realized based on foregoing of the present invention, all
Belong to the scope of the present invention.
Embodiment 1
Each raw material is weighed according to following component and consumption:
Deionized water 500 parts, trehalose 25 parts, oligomerization hyaluronate sodium 0.5 part, nicotiamide 9 parts, butanediol 50 parts, plant
Thing Liquid BPF PS 7 parts, 0.25 part of essence, Cremophor RH40 2.5 parts, Aesculus chinensis Bunge extract 65 parts, Rhizoma Chuanxiong extract
65 parts, Radix Scutellariae extract 60 parts, Rhizoma Polygonati Odorati extract 85 parts, Ganoderma extract 20 parts, licorice root extract 20 parts, 10% hydroxide
Potassium solution 15 parts, distilled water 75.75 parts.
In reaction vessel, trehalose, oligomerization hyaluronate sodium and nicotiamide are dissolved in stirring and dissolving in deionized water, rise
Temperature, to 85 DEG C of reaction 20min, obtains mixed solution I;
Temperature in reaction vessel is down to 40-50 DEG C, in mixed solution I, then adds butanediol, plant antiseptic agent
NPS, essence and Cremophor RH40 stirring 30min, add 10% potassium hydroxide solution, adjust pH to 5.0-6.0, obtain
Mixed solution II;
Temperature in reaction vessel is down to 30-40 DEG C, and then in mixed solution II, addition Aesculus chinensis Bunge extract, Rhizoma Chuanxiong carry
Take thing, Radix Scutellariae extract, Rhizoma Polygonati Odorati extract, Ganoderma extract and licorice root extract stirring 30min, add distilled water,
To the skin protection plant essence aerosol with sun-proof white-skinned face function.
Embodiment 2
Each raw material is weighed according to following component and consumption:
Deionized water 500 parts, trehalose 22 parts, oligomerization hyaluronate sodium 0.4 part, nicotiamide 7 parts, butanediol 45 parts, plant
Thing Liquid BPF PS 6 parts, 0.2 part of essence, Cremophor RH40 2 parts, Aesculus chinensis Bunge extract 60 parts, Rhizoma Chuanxiong extract 60
Part, Radix Scutellariae extract 50 parts, Rhizoma Polygonati Odorati extract 80 parts, Ganoderma extract 15 parts, licorice root extract 15 parts, 10% potassium hydroxide
Solution 8 parts, distilled water 100 parts.
In reaction vessel, trehalose, oligomerization hyaluronate sodium and nicotiamide are dissolved in stirring and dissolving in deionized water, rise
Temperature, to 85 DEG C of reaction 20min, obtains mixed solution I;
Temperature in reaction vessel is down to 40-50 DEG C, in mixed solution I, then adds butanediol, plant antiseptic agent
NPS, essence and Cremophor RH40 stirring 30min, add 10% potassium hydroxide solution, adjust pH to 5.0-6.0, obtain
Mixed solution II;
Temperature in reaction vessel is down to 30-40 DEG C, and then in mixed solution II, addition Aesculus chinensis Bunge extract, Rhizoma Chuanxiong carry
Take thing, Radix Scutellariae extract, Rhizoma Polygonati Odorati extract, Ganoderma extract and licorice root extract stirring 30min, add distilled water,
To the skin protection plant essence aerosol with sun-proof white-skinned face function.
Embodiment 3
Each raw material is weighed according to following component and consumption:
Deionized water 600 parts, trehalose 28 parts, oligomerization hyaluronate sodium 0.6 part, nicotiamide 12 parts, butanediol 55 parts, plant
Thing Liquid BPF PS 8 parts, 0.3 part of essence, Cremophor RH40 3 parts, Aesculus chinensis Bunge extract 70 parts, Rhizoma Chuanxiong extract 70
Part, Radix Scutellariae extract 70 parts, Rhizoma Polygonati Odorati extract 90 parts, Ganoderma extract 25 parts, licorice root extract 25 parts, 10% potassium hydroxide
Solution 20 parts, distilled water adds to 50 parts.
In reaction vessel, trehalose, oligomerization hyaluronate sodium and nicotiamide are dissolved in stirring and dissolving in deionized water, rise
Temperature, to 85 DEG C of reaction 20min, obtains mixed solution I;
Temperature in reaction vessel is down to 40-50 DEG C, in mixed solution I, then adds butanediol, plant antiseptic agent
NPS, essence and Cremophor RH40 stirring 30min, add 10% potassium hydroxide solution, adjust pH to 5.0-6.0, obtain
Mixed solution II;
Temperature in reaction vessel is down to 30-40 DEG C, and then in mixed solution II, addition Aesculus chinensis Bunge extract, Rhizoma Chuanxiong carry
Take thing, Radix Scutellariae extract, Rhizoma Polygonati Odorati extract, Ganoderma extract and licorice root extract stirring 30min, add distilled water,
To the skin protection plant essence aerosol with sun-proof white-skinned face function.
Embodiment 4
Each raw material is weighed according to following component and consumption:
Deionized water 400 parts, trehalose 20 parts, oligomerization hyaluronate sodium 0.4 part, nicotiamide 5 parts, butanediol 40 parts, plant
Thing Liquid BPF PS5 part, 0.1 part of essence, Cremophor RH40 2 parts, Aesculus chinensis Bunge extract 50 parts, Rhizoma Chuanxiong extract 50 parts,
Radix Scutellariae extract 30 parts, Rhizoma Polygonati Odorati extract 60 parts, Ganoderma extract 10 parts, licorice root extract 10 parts, 10% potassium hydroxide is molten
Liquid 10 parts, distilled water adds to 350 parts.
In reaction vessel, trehalose, oligomerization hyaluronate sodium and nicotiamide are dissolved in stirring and dissolving in deionized water, rise
Temperature, to 80 DEG C of reaction 20min, obtains mixed solution I;
Temperature in reaction vessel is down to 40-50 DEG C, in mixed solution I, then adds butanediol, plant antiseptic agent
NPS, essence and Cremophor RH40 stirring 20min, add 10% potassium hydroxide solution, adjust pH to 5.0-6.0, obtain
Mixed solution II;
Temperature in reaction vessel is down to 30-40 DEG C, and then in mixed solution II, addition Aesculus chinensis Bunge extract, Rhizoma Chuanxiong carry
Take thing, Radix Scutellariae extract, Rhizoma Polygonati Odorati extract, Ganoderma extract and licorice root extract stirring 20min, add distilled water,
To the skin protection plant essence aerosol with sun-proof white-skinned face function.
Embodiment 5
Each raw material is weighed according to following component and consumption:
Deionized water 700 parts, trehalose 30 parts, oligomerization hyaluronate sodium 0.6 part, nicotiamide 15 parts, butanediol 60 parts, plant
Thing Liquid BPF PS9 part, 0.4 part of essence, Cremophor RH40 3 parts, Aesculus chinensis Bunge extract 80 parts, Rhizoma Chuanxiong extract 80 parts,
Radix Scutellariae extract 80 parts, Rhizoma Polygonati Odorati extract 100 parts, Ganoderma extract 30 parts, licorice root extract 30 parts, 10% potassium hydroxide is molten
Liquid 30 parts, distilled water adds to 25 parts.
In reaction vessel, trehalose, oligomerization hyaluronate sodium and nicotiamide are dissolved in stirring and dissolving in deionized water, rise
Temperature, to 90 DEG C of reaction 20min, obtains mixed solution I;
Temperature in reaction vessel is down to 40-50 DEG C, in mixed solution I, then adds butanediol, plant antiseptic agent
NPS, essence and Cremophor RH40 stirring 60min, add 10% potassium hydroxide solution, adjust pH to 5.0-6.0, obtain
Mixed solution II;
Temperature in reaction vessel is down to 30-40 DEG C, and then in mixed solution II, addition Aesculus chinensis Bunge extract, Rhizoma Chuanxiong carry
Take thing, Radix Scutellariae extract, Rhizoma Polygonati Odorati extract, Ganoderma extract and licorice root extract stirring 60min, add distilled water,
To the skin protection plant essence aerosol with sun-proof white-skinned face function.
The skin protection plant essence aerosol with sun-proof white-skinned face function prepared by above-described embodiment 1-5 carries out sun-proof
Measure of merit.Experimental technique: with reference to the pertinent regulations of spf value detection in " cosmetics health specification " (version in 2002).In test
Choose the volunteer totally 120 that age bracket was at 15 years old to 50 years old, each 60 of men and women, IV type skin (seldom tan severely, but the most tanned
Body constitution), unglazed allergies.120 volunteers are divided into four groups, often organize 30 people (SPF take 30 for each person value), often organize and use this respectively
The skin protection plant essence aerosol of invention, experimental result is shown in Table 1.
Table 1
The skin protection plant essence aerosol with sun-proof white-skinned face function prepared by above-described embodiment 1-5 carries out cell
Survival rate is tested, and experimental technique is: the human epidermal cell HEK-n of trophophase of taking the logarithm, according to 1 × 105The concentration of cells/ml
It is inoculated in 96 orifice plates, every pore volume 200 μ L, after normal cultivation 24h, in cell culture fluid, adds embodiment of the present invention 1-5
Elite aerosol, after 5min, is respectively adopted 1MmH2O2Carry out oxidative damage and process 6h.After oxidative damage process terminates, take out 96
Hole culture fluid, abandons supernatant, after carefully rushing 2-3 time with PBS, adds the 200 μ L fresh medium containing 0.5mg/mlMTT, continues
At 37 DEG C, 5%CO2Under the conditions of cultivate 4h.After cultivation terminates, discarding MTT solution, every hole adds 100 μ LLDMSO, shaken well,
Survey each hole absorbance (A490) that wavelength is 490nm, calculate cell survival rate, result such as table 2.
Table 2
As can be seen from Table 1 and Table 2, the skin protection plant essence aerosol of the present invention has good sun-proof function, to carefully
The raising situation of born of the same parents' vigor is fine.
The skin protection plant essence aerosol with sun-proof white-skinned face function prepared by above-described embodiment 1-5 carries out whitening
Testing with spot-removal function, choose the volunteer totally 120 that age bracket was at 15 years old to 50 years old, man's volunteer 60 in test, female is certainly
Hope person 60, cardinal symptom is: freckle, sun speckle, the colour of skin are obscure.Volunteer is randomly divided into two groups, often group 60.
Test group: after every day face cleaning, sprays the skin protection plant essence aerosol of the present invention, often in face and exposing on skin
Day twice.Within 3 days, 7 days, 1 month, respectively add up once.
Evaluation criterion: experienced by patient's readme, and computer contrast skin texture figure identifies colour of skin whitening degree and mottle
Desalination degree.Effective: the colour of skin highlights, mottle color dodge.Invalid: the colour of skin and mottle are not any change before experiment.
Result on trial: be suitable for the skin protection plant essence aerosol of the present invention after 3 days, there is obvious whitening effect, effectively
Rate is up to 85%, and after using 7 days, effective percentage reaches 95%, and after using one month, effective percentage reaches 100%, and can substantially increase
The glossiness of skin, skin exquisiteness is mellow and full.Do not have an example that the phenomenon that skin is uncomfortable occurs.
Claims (7)
1. a skin protection plant essence aerosol with sun-proof white-skinned face function, it is characterised in that in parts by weight, bag
Include:
Deionized water 400-700 part, trehalose 20-30 part, oligomerization hyaluronate sodium 0.4-0.6 part, nicotiamide 5-15 part, fourth two
Alcohol 40-60 part, plant antiseptic agent NPS5-9 part, essence 0.1-0.4 part, Cremophor RH40 2-3 part, Aesculus chinensis Bunge extract
50-80 part, Rhizoma Chuanxiong extract 50-80 part, Radix Scutellariae extract 30-80 part, Rhizoma Polygonati Odorati extract 60-100 part, Ganoderma extract 10-
30 parts, licorice root extract 10-30 part, 10% potassium hydroxide solution 5-30 part, distilled water 25-350 part.
A kind of skin protection plant essence aerosol with sun-proof white-skinned face function the most according to claim 1, it is characterised in that
There is the skin protection plant essence aerosol of sun-proof white-skinned face function, in parts by weight, including: deionized water 500-600 part, sea
Algae sugar 22-28 part, oligomerization hyaluronate sodium 0.4-0.6 part, nicotiamide 7-12 part, butanediol 45-55 part, plant antiseptic agent NPS
6-8 part, essence 0.2-0.3 part, Cremophor RH40 2-3 part, Aesculus chinensis Bunge extract 60-70 part, Rhizoma Chuanxiong extract 60-70
Part, Radix Scutellariae extract 50-70 part, Rhizoma Polygonati Odorati extract 80-90 part, Ganoderma extract 15-25 part, licorice root extract 15-25 part,
10% potassium hydroxide solution 8-20 part, distilled water 50-100 part.
A kind of skin protection plant essence aerosol with sun-proof white-skinned face function the most according to claim 1, it is characterised in that
There is the skin protection plant essence aerosol of sun-proof white-skinned face function, in parts by weight, including: deionized water 500 parts, trehalose
25 parts, oligomerization hyaluronate sodium 0.5 part, nicotiamide 9 parts, butanediol 50 parts, plant antiseptic agent NPS 7 parts, 0.25 part of essence,
Cremophor RH40 2.5 parts, Aesculus chinensis Bunge extract 65 parts, Rhizoma Chuanxiong extract 65 parts, Radix Scutellariae extract 60 parts, Rhizoma Polygonati Odorati is extracted
Thing 85 parts, Ganoderma extract 20 parts, licorice root extract 20 parts, 10% potassium hydroxide solution 15 parts, distilled water 75.75 parts.
4. according to a kind of skin protection plant essence aerosol with sun-proof white-skinned face function described in claim 1-3 any one
Preparation method, it is characterised in that including:
Step one: in reaction vessel, trehalose, oligomerization hyaluronate sodium and nicotiamide are dissolved in stirring and dissolving in deionized water,
It is warming up to 80-90 DEG C of reaction, obtains mixed solution I;
Step 2: temperature in reaction vessel is down to 40-50 DEG C, then adds butanediol, plant antiseptic agent in mixed solution I
NPS, essence and Cremophor RH40 stirring, add 10% potassium hydroxide solution, obtain mixed solution II;
Step 3: temperature in reaction vessel is down to 30-40 DEG C, then adds Aesculus chinensis Bunge extract, river in mixed solution II
Rhizome of chuanxiong extract, Radix Scutellariae extract, Rhizoma Polygonati Odorati extract, Ganoderma extract and licorice root extract stirring, add distilled water, obtain
There is the skin protection plant essence aerosol of sun-proof white-skinned face function.
The preparation method of a kind of skin protection plant essence aerosol with sun-proof white-skinned face function the most according to claim 4,
It is characterized in that, the response time of described step one is 20min.
The preparation method of a kind of skin protection plant essence aerosol with sun-proof white-skinned face function the most according to claim 4,
It is characterized in that, the mixing time of described step 2 is 20-60min.
The preparation method of a kind of skin protection plant essence aerosol with sun-proof white-skinned face function the most according to claim 4,
It is characterized in that, the mixing time of described step 3 is 20-60min.
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Application publication date: 20161109 |