CN106039249A - 一种治疗风湿骨痛膏药及其制备方法 - Google Patents

一种治疗风湿骨痛膏药及其制备方法 Download PDF

Info

Publication number
CN106039249A
CN106039249A CN201610442287.2A CN201610442287A CN106039249A CN 106039249 A CN106039249 A CN 106039249A CN 201610442287 A CN201610442287 A CN 201610442287A CN 106039249 A CN106039249 A CN 106039249A
Authority
CN
China
Prior art keywords
parts
radix
rhizoma
plaster
unguent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610442287.2A
Other languages
English (en)
Inventor
鲍泽全
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201610442287.2A priority Critical patent/CN106039249A/zh
Publication of CN106039249A publication Critical patent/CN106039249A/zh
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • A61K35/583Snakes; Lizards, e.g. chameleons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/646Arachnids, e.g. spiders, scorpions, ticks or mites
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • A61K36/126Drynaria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/237Notopterygium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/254Acanthopanax or Eleutherococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/56Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/67Piperaceae (Pepper family), e.g. Jamaican pepper or kava
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716Clematis (leather flower)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/732Chaenomeles, e.g. flowering quince
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884Arisaema, e.g. Jack in the pulpit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8888Pinellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8988Gastrodia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Insects & Arthropods (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Inorganic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

本发明提供一种治疗风湿骨痛膏药及其制备方法,采用狗胫骨,马钱子、川乌,草乌,南星等祛风除湿、温经止痛,有抑制骨质增生、纤维增生的作用;采用血竭,乳香,防风恢复局部肌力作用;采用氮酮、冰片,肉桂使药效通过皮肤透达病灶治疗疾病。本发明风湿骨痛膏药采用酒精提纯中药和水煎浓缩中药与传统膏药基质相结合制成膏药,保证了原料成份质量,保证了药材成份不受损,使药效得到了提高,临床验证能够有效治疗骨质增生、椎间盘突出,完善迅速的治疗风寒湿所致颈肩腰腿痛。

Description

一种治疗风湿骨痛膏药及其制备方法
技术领域
本发明涉及中药膏药领域,具体是一种风湿骨痛膏药的制作方法。
背景技术
风湿骨痛膏药是一种外用膏药,用于风寒湿所致颈椎病、骨质增生、椎间盘突出,手足麻木及骨折后遗症等,它的主要成份有川乌、草乌,元胡、威灵仙、当归、马钱子、乳香、没药、血竭、冰片等药材,传统制作工艺,整个制作过程大都需要控制温度在200℃左右,药料有效成分损失很多,降低疗效。
发明内容
本发明的目的就是提供一种风湿骨痛膏药的制作方法,其能够保证原料成份质量,保证药材有效成份不受损,提高疗效。
为达到以上目的,一种治疗风湿骨痛的膏药,由以下重量比中药原料制成:血竭40-60份、冰片40-60份、乳香40-60份、没药40-60份、氮酮30-50份、远红外陶瓷粉30-50份,白花菜子40-60份、儿茶30-50份、丁香40-60份、肉桂40-60份,鹿茸40-60份、生马钱子60-80份、生川乌50-70份、生草乌50-70份、生南星40-60份、生半夏40-60份、川芎40-60份、细辛40-60份、土元40-60份、天麻40-60份、石决明50-70份、龙骨50-70份、地龙50-70份、秦艽40-60份、羌活40-60份、独活40-60份、全虫40-60份、杜仲40-60份、元胡40-60份、白芷40-60份、水蛭40-60份、防风40-60份、葛根30-50份、桂枝30-50份、苍耳子30-50份、荆芥30-50份、细辛30-50份、三七40-60份、栀子40-60份,生地50-70份、年健50-70份、海风藤40-60份、狗胫骨60-80份、五加皮40-60份、清风藤40-60份、乌蛇40-60份、苏木40-60份、透骨草40-60份、枳壳40-60份、当归40-60份、木瓜40-60份、牛膝40-60份、川断40-60份、苍术40-60份、自然铜40-60份、穿山甲40-60份、寄生40-60份、桑枝30-50份、石菖蒲30-50份、茜草30-50份、骨碎补40-60份、干姜40-60份、灵仙40-60份、赤芍40-60份、地风40-60份、生大黄40-60份
治疗风湿骨痛的膏药的制备方法包括以下步骤:
(1)将芝麻油置锅内,在温度200—250度熬制,当熬至滴水成珠时,下红丹收膏,后冷却作为膏药基质备用;
(2)将血竭40-60份、冰片40-60份、乳香40-60份、没药40-60份、氮酮30-50份、远红外陶瓷粉30-50份,白花菜子40-60份、儿茶30-50份、丁香40-60份、肉桂40-60份分别研成细粉,过筛后备用;
(3)将鹿茸40-60份、生马钱子60-80份、生川乌50-70份、生草乌50-70份、生南星40-60份、生半夏40-60份、川芎40-60份、细辛40-60份、土元40-60份、天麻40-60份、石决明50-70份、龙骨50-70份、地龙50-70份、秦艽40-60份、羌活40-60份、独活40-60份、全虫40-60份、杜仲40-60份、元胡40-60份、白芷40-60份、水蛭40-60份、防风40-60份、葛根30-50份、桂枝30-50份、苍耳子30-50份、荆芥30-50份、细辛30-50份、三七40-60份、栀子40-60份碎成粗粉,用酒精提取多次,合并乙醇提取液,浓缩成相对密度1.2-1.4的浸膏备用;
(4)将生地50-70份、年健50-70份、海风藤40-60份、狗胫骨60-80份、五加皮40-60份、清风藤40-60份、乌蛇40-60份、苏木40-60份、透骨草40-60份、枳壳40-60份、当归40-60份、木瓜40-60份、牛膝40-60份、川断40-60份、苍术40-60份、自然铜40-60份、穿山甲40-60份、寄生40-60份、桑枝30-50份、石菖蒲30-50份、茜草30-50份、骨碎补40-60份、干姜40-60份、灵仙40-60份、赤芍40-60份、地风40-60份、生大黄40-60份水煎多次,多次药液混合后过滤,浓缩成相对密度1.2-1.4的浸膏备用;
(5)将步骤(1)所制得的膏药基质用文火融化后,分别加入步骤(2)、(3)、(4)三步所得药料,搅拌均匀后分摊于膏药布上,制成膏药。
上述制备方法进一步优选为如下步骤:
(1)将芝麻油置锅内,在温度200—250度熬炼4小时,熬至滴水成珠时,下红丹收膏,后放凉水中冷却作为膏药基质备用;
(2)将血竭50份、冰片50份、乳香50份、没药50份、氮酮40份、远红外陶瓷粉40份、白花菜子40份、儿茶40份、丁香40份、肉桂40份分别研成细粉,过100目筛后备用;
(3)将鹿茸50份、生马钱子70份、生川乌60份、生草乌60份、生南星50份、生半夏50份、川芎50份、细辛50份、土元50份、天麻50份、石决明60份、龙骨60份、地龙60份、秦艽50份、羌活50份、独活50份、全虫50份、杜仲50份、元胡50份、白芷50份、水蛭50份、防风50份、葛根40份、桂枝40份、苍耳子40份、荆芥40份、细辛40份、三七50份、栀子50份碎成粗粉,用3倍量75%酒精提取3次,合并乙醇提取液,浓缩成相对密度1.2-1.4的浸膏备用;
(4)将生地60份、年健60份、海风藤50份、狗胫骨70份、五加皮50份、清风藤50份、乌蛇50份、苏木50份、透骨草50份、枳壳50份、当归50份、木瓜50份、牛膝50份、川断50份、苍术50份、自然铜50份、穿山甲50份、寄生50份、桑枝40份、石菖蒲40份、茜草40份、骨碎补40份、干姜50份、灵仙50份、赤芍50份、地风50份、生大黄50份水煎2次,每次1小时,二次药液混合后过滤,浓缩成相对密度1.2-1.4的浸膏备用。
(5)将步骤(1)所制得的膏药基质用文火融化后,分别加入步骤(2)、(3)、(4)三步所得药料,搅拌均匀后分摊于膏药布上,制成膏药。
所述步骤(5)中膏药基质的用量为步骤(2)、(3)、(4)三步所得药料总重量的3倍。
所述乙醇为体积浓度75%的乙醇。
经医学药典可知,膏药含有的主要成分的药用机理为:
鹿茸:性味咸湿,壮元阳、补气血、益精髓、强筋骨。
马钱子:性味苦温,散结消肿,通络止痛;
川乌:性味辛苦热,祛风除湿,散寒温经;
草乌:性味辛苦热,祛风湿, 散寒止痛;
半夏:性味辛温,有毒,燥湿化痰,降逆止呕,消痞散结;
天南星:性味苦辛温,有毒,燥湿化痰,祛风止痉,消肿止痛;
川芎:性味辛温,活血行气,止痛祛痛;
细辛:性味辛,温。 祛风散寒,行水开窍;
土元:性味咸寒,有小毒,破血逐瘀续筋骨;
天麻:性味甘平,息风止痉,平肝通络祛风;
石决明:性味咸寒,平肝潜阳,明目清肝;
龙骨:性味甘涩平,镇惊安神,敛汗固精,止血涩肠,生肌敛疮;
地龙:性味咸寒,清热息风,平喘利尿通络;
秦艽:性味辛苦寒,疗痹痛,清湿热治骨蒸;
羌活:性辛苦温。归膀胱肾经。解表散寒,祛风胜湿,止痛;
独活:性味辛苦温,解表止痹痛,祛除风湿;
全蝎:性味辛平,有毒,息风止痉,攻毒散解,通络止痛;
杜仲:性味甘温,补肝肾,安胎强筋骨;
元胡:元胡味辛、苦,性温。有活血散瘀,利气止痛的功能。
白芷:性辛温,肺胃经。祛风解表,通窍止痛,消肿排脓;
水蛭: 味苦、咸,性平。活血破瘀,通经消积;
防风:性辛、甘,微温祛风解表,胜湿止痛,止痉;
葛根:性味甘辛性凉解肌退热,透疹,生津止渴,升阳止泻;
桂枝:性辛甘温。归心肺膀胱经。发汗解表,温经通阳;
苍耳子:性辛苦温。有毒。归肺经。功效通鼻窍,祛风湿;
荆芥:性辛,微温。归肺肝经。祛风解表,透疹,止血;
红花:性味辛温,活血通经,祛瘀止痛;
三七:性温,味甘微苦止血、活血化瘀、消肿定痛;
生地:性味甘苦寒,清热凉血,养阴生津;
千年健:性味苦辛温,千年健强筋骨,祛风湿痹痛除;
海风藤:性味苦辛微温,祛风湿通经络;
狗胫骨:性味辛温,祛风定痛,强筋健骨,风湿痹痛,筋骨痿弱;
五加皮:性味辛苦温,疗痹强筋,利水消肿补虚;
青风藤:药味: 苦、辛, 祛风湿,通经络,利小便;
乌蛇:性味甘平,定惊止痉,通络祛风;
苏木:性味甘咸辛平,消肿止痛,活血疗伤,祛瘀通经;
透骨草:性辛苦平,祛风湿通络止痛,用于风湿痹痛;
枳壳:性味辛苦微寒,破气消积,除痞化痰;
当归:性味甘辛温,润肠调经,补血活血止痛;
木瓜:性味酸温,舒筋和胃,消食舒筋活络;
牛膝:性味苦酸涩平,补肝肾强腰膝,活血通经;
川断:性苦甘辛微温,补肝肾,行血脉,续筋骨;
苍术:性味辛苦温,除痹能解表,健脾燥湿治中焦;
自然铜:性味辛平,自然铜属黄铁矿,散瘀止痛疗骨伤;
穿山甲:性味咸微寒,活血消癥,通经排脓下乳;
栀子:性味苦,寒,泻火除烦;清热利湿;凉血解毒;
桑寄生:性味苦甘平,安胎强筋骨,补益肝肾除风湿;
桑枝:性味苦,平。清热,祛风,通络;
石菖蒲:性辛,微温,开窍豁痰,理气活血,散风去湿;
茜草:性味苦寒,凉血止血,化瘀通经;
元胡:性味辛温,补肾强骨,活血续筋骨;
干姜,性味辛温,温肺化痰通脉回阳,温中散寒;
威灵仙:性味辛咸温,祛风湿治骨鲠,通经络,治痰水积聚;
赤芍:性味苦微寒,散瘀止痛,凉血解毒;
地风:性味辛涩温,祛风除湿,行气止痛;
大黄:味苦微涩,攻积清热、泻火凉血、祛瘀解毒;
血竭:性味甘咸平,止敛生肌,活血化瘀能止痛;
冰片:性味辛苦微寒,清热止痛,开窍利神,消热消肿,
乳香:性味辛苦温,活血止痛,消肿生肌;
没药:性味归经:苦平,活血止痛,消肿生肌;
儿茶:性味苦涩凉,活血疗伤,止血生肌敛疮;
白花菜子:性味苦辛温有小毒,祛风散寒,活血止痛;
肉桂:性大热味辛甘。补火助阳,引火归源,散寒止痛,活血通经。
铅丹:性味辛寒,杀虫止痒,截疟铅丹,拔毒生肌;
氮酮:高效皮肤渗透剂,显著提高药物疗效,减少剂量和副作用;
远红外陶瓷粉:良好的远红外温热效果,吸收外界的热能后,释放出远红外线。
本发明在于几十年的临床实践与治疗过程中,总结出狗胫骨,马钱子、穿山甲,川乌,草乌,南星,陶瓷粉能祛风除湿、温经止痛、有抑制骨质增生、纤维增生的作用。乳香,没药、血竭,葛根,防风有恢复局部肌力作用。自然铜,土元,三七等疗筋养骨骨伤科经典要药,利用中药双向调节作用对骨科病症均有良效,氮酮、冰片,肉桂等使药效透过皮肤透达病灶达到治疗疾病的目的。本发明总结祖国医学对风痹、寒痹、骨痹和湿痹方剂用药的配伍规律,相互兼顾全面分析痹证治则治法的科学内涵结合临床经验研制出本膏药,功效活血化瘀、。祛风除湿、温经止痛、舒筋通络、柔筋养骨,对骨质增生、椎间盘突出,软组织损伤等各类骨科病症均有良效。此膏药是利用局部或穴位的外贴,通过皮肤肌肉的渗透吸收或刺激穴位,调节经络,平衡脏腑,以达到治疗疾病的目的,膏药外贴治疗疾病,避免内服药及针剂对患者所造成的毒副作用,是治疗中的捷径,能达到方便、安全、可靠的治疗目的。
具体实施方式
以下实施例仅用于对本发明做进一步的描述,并不是用来限制本发明的范围。
实施例1
一种治疗风湿骨痛的膏药的制备方法,其特征在于,包括以下步骤:
(1)将芝麻油置锅内,在温度200—250度熬制,当熬至滴水成珠时,下红丹收膏,后放凉水中冷却作为膏药基质备用;
(2)将血竭40份、冰片40份、乳香40份、没药40份、氮酮30份、远红外陶瓷粉30份,白花菜子40份、儿茶30份、丁香40份、肉桂40份分别研成细粉,过100目筛后备用。;
(3)将鹿茸40份、生马钱子60份、生川乌50份、生草乌50份、生南星50份、生半夏50份、川芎50份、细辛50份、土元50份、天麻50份、石决明60份、龙骨50份、地龙60份、秦艽50份、羌活50份、独活50份、全虫50份、杜仲50份、元胡40份、白芷50份、水蛭50份、防风50份、葛根40份、桂枝40份、苍耳子40份、荆芥40份、细辛40份、三七50份、栀子40份碎成粗粉,用3倍量75%酒精提取三次,合并乙醇提取液,浓缩成相对密度1.2-1.4的浸膏备用。
(4)将生地50份、年健60份、海风藤50份、狗胫骨60份、五加皮50份、清风藤50份、乌蛇50份、苏木50份、透骨草50份、枳壳50份、当归50份、木瓜50份、牛膝50份、川断50份、苍术50份、自然铜50份、穿山甲50份、寄生50份、桑枝40份、石菖蒲40份、茜草40份、骨碎补40份、干姜50份、灵仙50份、赤芍50份、地风50份、生大黄50份水煎二次,每次1小时,二次药液混合后过滤,浓缩成相对密度1.2-1.4的浸膏备用;
(5)将步骤(1)所制得的膏药基质用文火融化后,分别加入步骤(2)、(3)、(4)三步所得药料加入膏内,搅拌均匀后分摊于膏药布上,制成膏药。
实施例2
一种治疗风湿骨痛的膏药的制备方法,其特征在于,包括以下步骤:
(1)将芝麻油置锅内,在温度200—250度熬制,当熬至滴水成珠时,下红丹收膏,后放凉水中冷却作为膏药基质备用;
(2)将50份血竭、50份冰片、50份乳香、50份没药、40份氮酮、40份远红外陶瓷粉、40份白花菜子、40份儿茶、40份丁香、40份肉桂分别研成细粉,过100目筛后备用;
(3)将鹿茸50份、生马钱子50份、生川乌60份、生草乌60份、生南星50份、生半夏50份、川芎50份、细辛50份、土元50份、天麻50份、石决明60份、龙骨60份、地龙60份、秦艽50份、羌活50份、独活50份、全虫50份、杜仲50份、元胡50份、白芷50份、水蛭50份、防风50份、葛根40份、桂枝40份、苍耳子40份、荆芥40份、细辛40份、三七50份、栀子50份碎成粗粉,用3倍量75%酒精提取3次,合并乙醇提取液,浓缩成相对密度1.2-1.4的浸膏备用;
(4)将生地60份、年健60份、海风藤50份、狗胫骨70份、五加皮50份、清风藤50份、乌蛇50份、苏木50份、透骨草50份、枳壳50份、当归50份、木瓜50份、牛膝50份、川断50份、苍术50份、自然铜50份、穿山甲50份、寄生50份、桑枝40份、石菖蒲40份、茜草40份、骨碎补40份、干姜50份、灵仙50份、赤芍50份、地风50份、生大黄50份水煎2次,每次1小时,二次药液混合后过滤,浓缩成相对密度1.2-1.4的浸膏备用;
(5)将步骤(1)所制得的膏药基质用文火融化后,分别加入步骤(2)、(3)、(4)三步所得药料,膏药基质的用量为步骤(2)、(3)、(4)三步所得药料总重量的3倍;搅拌均匀后分摊于膏药布上,制成膏药。
实施例3
一种治疗风湿骨痛的膏药的制备方法,其特征在于,包括以下步骤:
(1)将芝麻油置锅内,在温度200—250度熬制,当熬至滴水成珠时,下红丹收膏,后放凉水中冷却作为膏药基质备用;
(2)将血竭60份、冰片60份、乳香60份、没药60份、氮酮50份、远红外陶瓷粉50份、白花菜子50份、儿茶50份、丁香50份、肉桂50份分别研成细粉,过筛后备用;
(3)将鹿茸60份、生马钱子60份、生川乌70份、生草乌70份、生南星60份、生半夏60份、川芎60份、细辛60份、土元60份、天麻60份、石决明70份、龙骨70份、地龙70份、秦艽60份、羌活60份、独活60份、全虫60份、杜仲60份、元胡60份、白芷60份、水蛭60份、防风60份、葛根50份、桂枝50份、苍耳子50份、荆芥50份、细辛50份、三七60份、栀子60份碎成粗粉,用3倍量75%酒精提取3次,合并乙醇提取液,浓缩成相对密度1.2-1.4的浸膏备用;
(4)将70份生地、70份年健、60份海风藤、80份狗胫骨、60份五加皮、60份清风藤、60份乌蛇、60份苏木、60份透骨草、60份枳壳、60份当归、60份木瓜、60份牛膝、60份川断、60份苍术、60份自然铜、60份穿山甲、60份寄生、50份桑枝、50份石菖蒲、50份茜草、50份骨碎补、60份干姜、60份灵仙、60份赤芍、60份地风、60份生大黄水煎2次,每次1小时,二次药液混合后过滤,浓缩成相对密度1.2-1.4的浸膏备用;
(5)将步骤(1)所制得的膏药基质用文火融化后,分别加入步骤(2)、(3)、(4)三步所得药料,膏药基质的用量为步骤(2)、(3)、(4)三步所得药料总重量的3倍;搅拌均匀后分摊于膏药布上,制成膏药。
临床实验观察,
1.一般资料患者共计1660例,其中男性920人,女性740人
2.使用方法随机使用实施例所述方法得到膏药,时间10—50天左右
3.疗效判定标准:
治愈:患者疼痛消失,原症状与阳性体征消失,行动正常.
有效:患者疼痛明显减轻,原症状与阳性体征明显改善,活动基本正常。
无效:患者疼痛无减轻,原症状与阳性体征无变化,行动无改善。
4.本发明膏药治疗效果统计,
将实施例1-3制得膏药分别做以下具体应用:
1.刘** 女47岁 已婚 职工 东营市人 2015年11月6日就诊。就诊前天,在单位扫雪时,不慎将颈部扭伤,当即颈部肌肉剧烈疼痛,并向右背放射,自行在家中拨火罐无效,来我处就诊。查体:颈部功能活动受限,活动时疼痛加剧,用拇指触及颈部右侧肌肉僵硬,可触及条索状物,并压痛++,右上肢抬举时有痛麻感,X光拍片检查提示:颈椎生理曲度变直,颈5.6椎后缘见轻微增生。诊断:外伤性颈椎病。治疗:理疗后局部贴敷膏药1贴,5天一次,连用2次,症状完全消失,终止治疗,随访一年未复发。2.宋** 男42岁 已婚 铜厂工人 滨州人 2012年8月7日就诊,就诊前在单位卸原料时,腰部扭伤,随后腰部疼痛难忍,不能弯腰活动,疼痛向下肢放射,来我处就诊。查体:病人面容痛苦,腰部活动功能受限,腰部活动度,双拇指触及腰部肌肉痉挛,并压痛+++,X光拍片检查指示:未见腰部骨质异常。诊断:急性腰扭伤。治疗:局部用松解手法后,外用2贴膏药,5天更换一次,连用2次后,患者病症消失,查腰椎活动度,局部无压痛,终止治疗 。3.朱** 67岁 已婚 邮电局职工 东营市人 2014年12月1号就诊。 患者腰痛,右下肢间断性麻木6年,常因天气变化,劳累后,症状加剧,四处诊治效不佳,故来我处治疗。查体腰椎侧弯,腰椎3-5椎旁压痛,腰部肌肉呈板状,压痛,CT检查提示:腰椎1-5均增生,并形成骨桥。诊断:腰椎骨性关节炎。治疗:嘱患者膏药外敷,连用50天后,症状逐渐消失,终止治疗,随访2年未复发。
以上仅仅是本发明给出的几个典型的实施例,经过试验验证,在本发明保护范围内选择其他物料以及其他配比,制作成散剂,软膏剂等同样能够得到本发明所述的膏药一样的效果,在此就不一一赘述。

Claims (5)

1.一种治疗风湿骨痛的膏药,其特征在于,由以下重量比中药原料制成,血竭40-60份、冰片40-60份、乳香40-60份、没药40-60份、氮酮30-50份、远红外陶瓷粉30-50份,白花菜子40-60份、儿茶30-50份、丁香40-60份、肉桂40-60份,鹿茸40-60份、生马钱子60-80份、生川乌50-70份、生草乌50-70份、生南星40-60份、生半夏40-60份、川芎40-60份、细辛40-60份、土元40-60份、天麻40-60份、石决明50-70份、龙骨50-70份、地龙50-70份、秦艽40-60份、羌活40-60份、独活40-60份、全虫40-60份、杜仲40-60份、元胡40-60份、白芷40-60份、水蛭40-60份、防风40-60份、葛根30-50份、桂枝30-50份、苍耳子30-50份、荆芥30-50份、细辛30-50份、三七40-60份、栀子40-60份,生地50-70份、年健50-70份、海风藤40-60份、狗胫骨60-80份、五加皮40-60份、清风藤40-60份、乌蛇40-60份、苏木40-60份、透骨草40-60份、枳壳40-60份、当归40-60份、木瓜40-60份、牛膝40-60份、川断40-60份、苍术40-60份、自然铜40-60份、穿山甲40-60份、寄生40-60份、桑枝30-50份、石菖蒲30-50份、茜草30-50份、骨碎补40-60份、干姜40-60份、灵仙40-60份、赤芍40-60份、地风40-60份、生大黄40-60份。
2.一种治疗风湿骨痛的膏药的制备方法,其特征在于,包括以下步骤:
(1)将芝麻油置锅内,在温度200—250度熬制,当熬至滴水成珠时,下红丹收膏,后冷却作为膏药基质备用;
(2)将血竭40-60份、冰片40-60份、乳香40-60份、没药40-60份、氮酮30-50份、远红外陶瓷粉30-50份,白花菜子40-60份、儿茶30-50份、丁香40-60份、肉桂40-60份分别研成细粉,过筛后备用;
(3)将鹿茸40-60份、生马钱子60-80份、生川乌50-70份、生草乌50-70份、生南星40-60份、生半夏40-60份、川芎40-60份、细辛40-60份、土元40-60份、天麻40-60份、石决明50-70份、龙骨50-70份、地龙50-70份、秦艽40-60份、羌活40-60份、独活40-60份、全虫40-60份、杜仲40-60份、元胡40-60份、白芷40-60份、水蛭40-60份、防风40-60份、葛根30-50份、桂枝30-50份、苍耳子30-50份、荆芥30-50份、细辛30-50份、三七40-60份、栀子40-60份碎成粗粉,用酒精提取数次,合并乙醇提取液,浓缩成相对密度1.2-1.4的浸膏备用;
(4)将生地50-70份、年健50-70份、海风藤40-60份、狗胫骨60-80份、五加皮40-60份、清风藤40-60份、乌蛇40-60份、苏木40-60份、透骨草40-60份、枳壳40-60份、当归40-60份、木瓜40-60份、牛膝40-60份、川断40-60份、苍术40-60份、自然铜40-60份、穿山甲40-60份、寄生40-60份、桑枝30-50份、石菖蒲30-50份、茜草30-50份、骨碎补40-60份、干姜40-60份、灵仙40-60份、赤芍40-60份、地风40-60份、生大黄40-60份水煎多次,多次药液混合后过滤,浓缩成相对密度1.2-1.4的浸膏备用;
(5)将步骤(1)所制得的膏药基质用文火融化后,分别加入步骤(2)、(3)、(4)三步所得药料,搅拌均匀后分摊于膏药布上,制成膏药。
3.根据权利要求2所述的治疗风湿骨痛的膏药的制备方法,其特征在于,包括如下步骤:
(1)将芝麻油置锅内,在温度200—250度熬炼4小时,熬至滴水成珠时,下红丹收膏,后放凉水中冷却作为膏药基质备用;
(2)将血竭50份、冰片50份、乳香50份、没药50份、氮酮40份、远红外陶瓷粉40份、白花菜子40份、儿茶40份、丁香40份、肉桂40份分别研成细粉,过100目筛后备用;
(3)将鹿茸50份、生马钱子70份、生川乌60份、生草乌60份、生南星50份、生半夏50份、川芎50份、细辛50份、土元50份、天麻50份、石决明60份、龙骨60份、地龙60份、秦艽50份、羌活50份、独活50份、全虫50份、杜仲50份、元胡50份、白芷50份、水蛭50份、防风50份、葛根40份、桂枝40份、苍耳子40份、荆芥40份、细辛40份、三七50份、栀子50份碎成粗粉,用3倍量75%酒精提取3次,合并乙醇提取液,浓缩成相对密度1.2-1.4的浸膏备用;
(4)将生地60份、年健60份、海风藤50份、狗胫骨70份、五加皮50份、清风藤50份、乌蛇50份、苏木50份、透骨草50份、枳壳50份、当归50份、木瓜50份、牛膝50份、川断50份、苍术50份、自然铜50份、穿山甲50份、寄生50份、桑枝40份、石菖蒲40份、茜草40份、骨碎补40份、干姜50份、灵仙50份、赤芍50份、地风50份、生大黄50份水煎2次,每次1小时,二次药液混合后过滤,浓缩成相对密度1.2-1.4的浸膏备用。
(5)将步骤(1)所制得的膏药基质用文火融化后,分别加入步骤(2)、(3)、(4)三步所得药料,搅拌均匀后分摊于膏药布上,制成膏药。
4.根据权利要求2或3所述的治疗风湿骨痛的膏药的制备方法,其特征在于,所述步骤(5)中膏药基质的用量为步骤(2)、(3)、(4)三步所得药料总重量的3倍。
5.根据权利要求2或3所述的治疗风湿骨痛的膏药的制备方法,其特征在于,所述乙醇为体积浓度75%的乙醇。
CN201610442287.2A 2016-06-21 2016-06-21 一种治疗风湿骨痛膏药及其制备方法 Pending CN106039249A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610442287.2A CN106039249A (zh) 2016-06-21 2016-06-21 一种治疗风湿骨痛膏药及其制备方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610442287.2A CN106039249A (zh) 2016-06-21 2016-06-21 一种治疗风湿骨痛膏药及其制备方法

Publications (1)

Publication Number Publication Date
CN106039249A true CN106039249A (zh) 2016-10-26

Family

ID=57168475

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610442287.2A Pending CN106039249A (zh) 2016-06-21 2016-06-21 一种治疗风湿骨痛膏药及其制备方法

Country Status (1)

Country Link
CN (1) CN106039249A (zh)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106309954A (zh) * 2016-11-07 2017-01-11 穆林涛 一种治疗骨病的膏药
CN106539953A (zh) * 2016-10-27 2017-03-29 金秀瑶族自治县瑶医医院 瑶王膏及其制备方法
CN107050125A (zh) * 2017-03-10 2017-08-18 宫玉泰 一种治疗颈肩腰腿痛和坐骨神经痛的中药组合物
CN107456554A (zh) * 2017-08-09 2017-12-12 黄明金 一种治疗痹症的膏药及其制作方法
CN108042717A (zh) * 2018-01-15 2018-05-18 程杰 一种膏药及其制备方法
CN108245648A (zh) * 2016-12-27 2018-07-06 孙明月 一种风湿骨痛贴及其制作方法
CN110882352A (zh) * 2018-09-05 2020-03-17 林光辉 一种外敷用的林氏筋骨康药散

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101773642A (zh) * 2010-02-26 2010-07-14 陈德林 活血化瘀骨康灵膏药配方及制备方法
CN102188673A (zh) * 2010-03-17 2011-09-21 赵贵凤 强筋壮骨贴膏及其制备和应用
CN105079583A (zh) * 2015-09-30 2015-11-25 陕西玉麟能源开发有限公司 一种治骨痛贴膏

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101773642A (zh) * 2010-02-26 2010-07-14 陈德林 活血化瘀骨康灵膏药配方及制备方法
CN102188673A (zh) * 2010-03-17 2011-09-21 赵贵凤 强筋壮骨贴膏及其制备和应用
CN105079583A (zh) * 2015-09-30 2015-11-25 陕西玉麟能源开发有限公司 一种治骨痛贴膏

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106539953A (zh) * 2016-10-27 2017-03-29 金秀瑶族自治县瑶医医院 瑶王膏及其制备方法
CN106309954A (zh) * 2016-11-07 2017-01-11 穆林涛 一种治疗骨病的膏药
CN108245648A (zh) * 2016-12-27 2018-07-06 孙明月 一种风湿骨痛贴及其制作方法
CN107050125A (zh) * 2017-03-10 2017-08-18 宫玉泰 一种治疗颈肩腰腿痛和坐骨神经痛的中药组合物
CN107456554A (zh) * 2017-08-09 2017-12-12 黄明金 一种治疗痹症的膏药及其制作方法
CN108042717A (zh) * 2018-01-15 2018-05-18 程杰 一种膏药及其制备方法
CN110882352A (zh) * 2018-09-05 2020-03-17 林光辉 一种外敷用的林氏筋骨康药散

Similar Documents

Publication Publication Date Title
CN102363037B (zh) 一种治疗风湿、类风湿性关节炎和颈肩腰腿疼的外用膏药
CN106039249A (zh) 一种治疗风湿骨痛膏药及其制备方法
CN103055244B (zh) 一种治疗风湿骨病的膏药及其制备方法
CN101804190B (zh) 一种舒筋活血通痹膏及其制备方法
CN104288538A (zh) 一种治疗颈肩腰腿疾病的膏药及其制备方法
CN105983036A (zh) 一种治疗颈肩腰腿痛的膏药
CN112168872A (zh) 一种中药热灸膏及其制备方法
CN102552816B (zh) 一种治疗疼痛的膏药及其制作方法
CN103768315A (zh) 一种接骨活血的正骨膏药
CN103251914A (zh) 治疗风湿骨病的药物
CN103142938A (zh) 一种治疗跌打损伤骨折的膏药
CN103736069B (zh) 一种治疗风湿病的膏药及其制备方法
CN103784804A (zh) 一种治疗前列腺增生的中药组合物
CN106177819A (zh) 一种用于颈椎病的外用中药组合物、制备方法及其应用
CN104815286A (zh) 一种治疗三叉神经痛的中药配方
CN104225534A (zh) 一种治疗腰肩脚风湿病膏药及其制备方法
CN103301430A (zh) 一种治疗骨质增生、腰腿痛的药物及其制备方法
CN107115505A (zh) 一种活血祛瘀止痛膏药及其制备方法
CN103394042A (zh) 一种辅助治疗骨伤的中药酊剂
CN102949507B (zh) 一种治疗腰腿痛的中药洗剂及其制备方法
CN105561270A (zh) 一种外敷止痛中草药及其制备方法
CN104740450A (zh) 一种治疗风湿病的中药浴足粉及其制备和使用方法
CN104758527A (zh) 一种治疗腰腿痛的中药组合物
CN103961618A (zh) 一种治疗风寒湿邪引起的疼痛膏药
CN110151886A (zh) 一种治疗颈肩腰腿疼的膏药

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20161026

RJ01 Rejection of invention patent application after publication