CN106039238A - Traditional Chinese medicinal composition for treating depressive neurosis, and preparation method and application thereof - Google Patents
Traditional Chinese medicinal composition for treating depressive neurosis, and preparation method and application thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicinal composition for treating depressive neurosis. The composition is prepared from, by weight, 10-15 parts of Medulla Junci, 20-25 parts of Cortex Albiziae, 15-20 parts of Rhizoma Atractylodis Macrocephalae, 13-18 parts of Radix Curcumae Aromaticae, 13-18 parts of radix bupleuri, 15-20 parts of Chinese magnoliavine, 15-20 parts of Poria cocos, 15-20 parts of Fructus Gardeniae, 10-15 parts of white peony root, 10-15 parts of Valeriana officinalis L. and 15-20 parts of Folium Eucommiae. The invention also discloses a preparation method of the composition, and an application of the composition in depressive neurosis treatment medicines as an effective component. All raw material traditional Chinese medicines complement each other, and cooperate to realize the efficacy of soothing the liver and resolving depression, invigorating spleen and benefiting qi, tonifying liver and kidney, and calming heart and tranquilizing mind, so the composition has a definite treatment effect on the depressive neurosis, and has the advantages of substantial treatment effect, high safety, no toxic or side effects, realization of the effective rate reaching 99.4%, and very good promotion and use values.
Description
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to a kind of Chinese medicine composition treating depressive neurosis and preparation side thereof
Method and application.
Background technology
Depressive neurosis, also known as dysthymic disorder, is that a kind of lasting emotion caused due to socio-psychological factors presses down
Strongly fragrant, its lesser extent, the course of disease is relatively delayed.Have the feature that (1) has lasting depressed, dejected, constrain, with Jiao
Consider, Somatic discomfort and sleep disorder.(2) without the neurosal feature of major depressive, as sluggish, unreal without obvious psychomotor activity
Circadian change caused by feel, vain hope and the change of abiology aspect, early awakening insomnia, losing weight without obvious cause
Deng.(3) contact with surrounding well, daily work, learn and life Non Apparent Abnormality.(4) there is insight, can actively seek medical advice.
Common psychosocial factor has man and wife to quarrel, divorced, the difference of relatives, unexpected disability, operational difficulties, interpersonal difficulty,
Fail.Primary disease women is common, and many onsets are in juvenile era.The Most patients course of disease is longer, prognosis bona, especially spirit
Factor is single, without depressed personality person.But such as Relapse rate, often fluctuate along with the impact of Nervous and Mental Factors, there is depressed personality barrier
The person of hindering, the course of disease relatively delays, and prognosis is not good enough.Primary disease treatment needs psychotherapy and Drug therapy to carry out simultaneously, can obtain good result.
At present, depressive neurosis is treated frequently with tricyclic antidepressants amitriptyline, chlorine the third miaow prolixity etc. in psychiatric department, although effective
Hurry up, but its anticholinergic side effects (such as dizziness, postural hypotension, xerostomia, dysuria etc.) and induced cardiotoxicity are (such as the heart
Dynamic overrun, conduction block etc.) make patient not be easily accepted by, or more after end-of-dose failure, obstinate, affect the social merit of patient for a long time
Energy and quality of life.
Summary of the invention
For the deficiencies in the prior art, the invention provides the Chinese drug-treated group of the treatment depressive neurosis of a kind of determined curative effect
Compound and its preparation method and application.
For realizing object above, the present invention is achieved by the following technical programs:
A kind of Chinese medicine composition treating depressive neurosis, is made up of the raw material of following weight portion: Medulla Junci 10-15
Part, Cortex Albiziae 20-25 part, Rhizoma Atractylodis Macrocephalae 15-20 part, Radix Curcumae 13-18 part, Radix Bupleuri 13-18 part, Fructus Schisandrae Chinensis 15-20 part, Poria 15-20
Part, Fructus Gardeniae 15-20 part, Radix Paeoniae Alba 10-15 part, Rhizoma et radix valerianae 10-15 part, Folium Eucommiae 15-20 part.
Preferably, it is made up of the raw material of following weight portion: Medulla Junci 12 parts, Cortex Albiziae 21 parts, the Rhizoma Atractylodis Macrocephalae 17 parts, Radix Curcumae 15
Part, Radix Bupleuri 15 parts, Fructus Schisandrae Chinensis 18 parts, 20 parts of Poria, Fructus Gardeniae 17 parts, the Radix Paeoniae Alba 14 parts, Rhizoma et radix valerianae 12 parts, Folium Eucommiae 16 parts.
The preparation method of the Chinese medicine composition for the treatment of depressive neurosis, comprises the following steps:
1) Radix Curcumae, the Rhizoma Atractylodis Macrocephalae, Rhizoma et radix valerianae are taken, mixing, it is placed in volatile oil extractor, soaks, decompression distillation 1h, collects
Distillate, second distillation, ether extracts, and is dried, obtains volatile oil, Aqueous extracts and filtering residue standby；
2) by Medulla Junci, Folium Eucommiae, Radix Bupleuri, Poria and step 1) in filtering residue mixing, add 8 times amount water, decoct extraction 2
Secondary, each 1h, filters, discards medicinal residues, obtain Aqueous extracts；
3) Cortex Albiziae, Fructus Schisandrae Chinensis, Fructus Gardeniae, the Radix Paeoniae Alba are taken, mixing, add 8 times amount 70% alcohol heating reflux extraction 2 times, often
Secondary 1h, filters, obtains alcohol extract；
4) combining step 1) Aqueous extracts and volatile oil, step 2) in Aqueous extracts, step 3) alcohol extract, be concentrated to give leaching
Cream, is dried, is ground into medicated powder；
5) in medicated powder, add pharmaceutically acceptable carrier, be prepared as corresponding pharmaceutical dosage form.
Preferably, described dosage form is tablet, granule, capsule or pill.
Treatment depressive neurosis Chinese medicine composition as treatment depressive neurosis medicine effective ingredient should
With.
In the present invention, effect of each raw material Chinese medicine is as follows:
Medulla Junci: cold nature, sweet in the mouth, light, GUIXIN warp, lung meridian, small intestine meridian, clearing away heart-fire, diuresis are wet with controlling pyretic stranguria, water
The edema inside stopped, dysuria, oedema due to nephritis, dysphoria and insomnia, nocturnal fretfulness in infants etc..
Cortex Albiziae: property put down, sweet in the mouth, GUIXIN warp, Liver Channel, lung meridian, resolving stagnation for tranquilization, promoting blood circulation and detumescence, modern times with control irritability,
Melancholy insomnia.
The Rhizoma Atractylodis Macrocephalae: warm in nature, sweet in the mouth, hardship, return spleen channel, stomach warp, invigorating the spleen and benefiting QI, dampness diuretic.
Radix Curcumae: cold in nature, acrid in the mouth, hardship, return Liver Channel, heart channel, lung meridian, promoting blood circulation and stopping pain, circulation of qi promoting scabies, heart fire-clearing upset-relieving, function of gallbladder promoting to move back
Yellow.
Radix Bupleuri: cold nature, bitter in the mouth, return Liver Channel, gallbladder meridian, lung meridian, reconciling superficies and interior, soothing the liver yang invigorating, pharmacological testing proves, has
Antiinflammatory, antipyretic, calm, analgesia, antitussive and anticonvulsant action；Hepatic injury can be alleviated and promote bile secretion.
Fructus Schisandrae Chinensis: warm in nature, sour in the mouth, sweet, return lung meridian, heart channel, kidney channel, restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.
Poria: property is put down, sweet in the mouth, light, GUIXIN warp, lung meridian, spleen channel, kidney channel, promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.
Fructus Gardeniae: cold in nature, bitter in the mouth, GUIXIN warp, lung meridian, tri-jiao channel, pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body, with controlling epidemic febrile disease
Heat stagnation ambition, vexed, gloomy, restlessness is peaceful, sleep disorder.
The Radix Paeoniae Alba: cold nature, bitter in the mouth, acid, return Liver Channel, spleen channel, suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.
Rhizoma et radix valerianae: property is put down, bitter in the mouth is micro-sweet, GUIXIN warp, Liver Channel, has effect of mind tranquilizing and the heart calming.
Folium Eucommiae: warm in nature, taste is micro-pungent.Return Liver Channel, kidney channel, invigorating the liver and kidney, bone and muscle strengthening.
The method have the benefit that in the present invention, each raw material Chinese medicine complements each other, synergism, play dispersing the stagnated live-QI to relieve the stagnation of QI, spleen invigorating altogether
QI invigorating, liver and kidney tonifying, effect of mind tranquilizing and the heart calming, there is definite curative effect for depressive neurosis, and evident in efficacy, safety is without secondary
Effect, effective percentage reaches 99.4%, has good popularizing value.
Detailed description of the invention
For making the purpose of the embodiment of the present invention, technical scheme and advantage clearer, below in conjunction with the embodiment of the present invention,
Technical scheme in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is the present invention one
Divide embodiment rather than whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art are not making
The every other embodiment obtained under creative work premise, broadly falls into the scope of protection of the invention.
Embodiment 1:
A kind of Chinese medicine composition treating depressive neurosis, is made up of the raw material of following weight portion: Medulla Junci 12 parts, conjunction
Joyous skin 21 parts, the Rhizoma Atractylodis Macrocephalae 17 parts, Radix Curcumae 15 parts, Radix Bupleuri 15 parts, Fructus Schisandrae Chinensis 18 parts, 20 parts of Poria, Fructus Gardeniae 17 parts, the Radix Paeoniae Alba 14 parts, figured silk fabrics
Grass 12 parts, Folium Eucommiae 16 parts.
The preparation method of the Chinese medicine composition for the treatment of depressive neurosis, comprises the following steps:
1) Radix Curcumae, the Rhizoma Atractylodis Macrocephalae, Rhizoma et radix valerianae are taken, mixing, it is placed in volatile oil extractor, soaks, decompression distillation 1h, collects
Distillate, second distillation, ether extracts, and is dried, obtains volatile oil, Aqueous extracts and filtering residue standby；
2) by Medulla Junci, Folium Eucommiae, Radix Bupleuri, Poria and step 1) in filtering residue mixing, add 8 times amount water, decoct extraction 2
Secondary, each 1h, filters, discards medicinal residues, obtain Aqueous extracts；
3) Cortex Albiziae, Fructus Schisandrae Chinensis, Fructus Gardeniae, the Radix Paeoniae Alba are taken, mixing, add 8 times amount 70% alcohol heating reflux extraction 2 times, often
Secondary 1h, filters, obtains alcohol extract；
4) combining step 1) Aqueous extracts and volatile oil, step 2) in Aqueous extracts, step 3) alcohol extract, be concentrated to give leaching
Cream, is dried, is ground into medicated powder；
5) in medicated powder, add pharmaceutically acceptable carrier, be prepared as tablet.
Embodiment 2:
A kind of Chinese medicine composition treating depressive neurosis, is made up of the raw material of following weight portion: Medulla Junci 13 parts, conjunction
Joyous skin 24 parts, the Rhizoma Atractylodis Macrocephalae 18 parts, Radix Curcumae 16 parts, Radix Bupleuri 16 parts, Fructus Schisandrae Chinensis 20 parts, 18 parts of Poria, Fructus Gardeniae 18 parts, the Radix Paeoniae Alba 12 parts, figured silk fabrics
Grass 13 parts, Folium Eucommiae 17 parts.
The preparation method of the Chinese medicine composition for the treatment of depressive neurosis, comprises the following steps:
1) Radix Curcumae, the Rhizoma Atractylodis Macrocephalae, Rhizoma et radix valerianae are taken, mixing, it is placed in volatile oil extractor, soaks, decompression distillation 1h, collects
Distillate, second distillation, ether extracts, and is dried, obtains volatile oil, Aqueous extracts and filtering residue standby；
2) by Medulla Junci, Folium Eucommiae, Radix Bupleuri, Poria and step 1) in filtering residue mixing, add 8 times amount water, decoct extraction 2
Secondary, each 1h, filters, discards medicinal residues, obtain Aqueous extracts；
3) Cortex Albiziae, Fructus Schisandrae Chinensis, Fructus Gardeniae, the Radix Paeoniae Alba are taken, mixing, add 8 times amount 70% alcohol heating reflux extraction 2 times, often
Secondary 1h, filters, obtains alcohol extract；
4) combining step 1) Aqueous extracts and volatile oil, step 2) in Aqueous extracts, step 3) alcohol extract, be concentrated to give leaching
Cream, is dried, is ground into medicated powder；
5) in medicated powder, add pharmaceutically acceptable carrier, be prepared as granule.
Embodiment 3:
A kind of Chinese medicine composition treating depressive neurosis, is made up of the raw material of following weight portion: Medulla Junci 14 parts, conjunction
Joyous skin 22 parts, the Rhizoma Atractylodis Macrocephalae 16 parts, Radix Curcumae 15 parts, Radix Bupleuri 16 parts, Fructus Schisandrae Chinensis 17 parts, 18 parts of Poria, Fructus Gardeniae 16 parts, the Radix Paeoniae Alba 13 parts, figured silk fabrics
Grass 10 parts, Folium Eucommiae 15 parts.
The preparation method of the Chinese medicine composition for the treatment of depressive neurosis, comprises the following steps:
1) Radix Curcumae, the Rhizoma Atractylodis Macrocephalae, Rhizoma et radix valerianae are taken, mixing, it is placed in volatile oil extractor, soaks, decompression distillation 1h, collects
Distillate, second distillation, ether extracts, and is dried, obtains volatile oil, Aqueous extracts and filtering residue standby；
2) by Medulla Junci, Folium Eucommiae, Radix Bupleuri, Poria and step 1) in filtering residue mixing, add 8 times amount water, decoct extraction 2
Secondary, each 1h, filters, discards medicinal residues, obtain Aqueous extracts；
3) Cortex Albiziae, Fructus Schisandrae Chinensis, Fructus Gardeniae, the Radix Paeoniae Alba are taken, mixing, add 8 times amount 70% alcohol heating reflux extraction 2 times, often
Secondary 1h, filters, obtains alcohol extract；
4) combining step 1) Aqueous extracts and volatile oil, step 2) in Aqueous extracts, step 3) alcohol extract, be concentrated to give leaching
Cream, is dried, is ground into medicated powder；
5) in medicated powder, add pharmaceutically acceptable carrier, be prepared as capsule.
Embodiment 4:
A kind of Chinese medicine composition treating depressive neurosis, is made up of the raw material of following weight portion: Medulla Junci 10 parts, conjunction
Joyous skin 25 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Radix Curcumae 18 parts, Radix Bupleuri 13 parts, Fructus Schisandrae Chinensis 20 parts, 15 parts of Poria, Fructus Gardeniae 20 parts, the Radix Paeoniae Alba 10 parts, figured silk fabrics
Grass 15 parts, Folium Eucommiae 15 parts.
The preparation method of the Chinese medicine composition for the treatment of depressive neurosis, comprises the following steps:
1) Radix Curcumae, the Rhizoma Atractylodis Macrocephalae, Rhizoma et radix valerianae are taken, mixing, it is placed in volatile oil extractor, soaks, decompression distillation 1h, collects
Distillate, second distillation, ether extracts, and is dried, obtains volatile oil, Aqueous extracts and filtering residue standby；
2) by Medulla Junci, Folium Eucommiae, Radix Bupleuri, Poria and step 1) in filtering residue mixing, add 8 times amount water, decoct extraction 2
Secondary, each 1h, filters, discards medicinal residues, obtain Aqueous extracts；
3) Cortex Albiziae, Fructus Schisandrae Chinensis, Fructus Gardeniae, the Radix Paeoniae Alba are taken, mixing, add 8 times amount 70% alcohol heating reflux extraction 2 times, often
Secondary 1h, filters, obtains alcohol extract；
4) combining step 1) Aqueous extracts and volatile oil, step 2) in Aqueous extracts, step 3) alcohol extract, be concentrated to give leaching
Cream, is dried, is ground into medicated powder；
5) in medicated powder, add pharmaceutically acceptable carrier, be prepared as pill.
Embodiment 5:
A kind of Chinese medicine composition treating depressive neurosis, is made up of the raw material of following weight portion: Medulla Junci 15 parts, conjunction
Joyous skin 20 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, Radix Curcumae 13 parts, Radix Bupleuri 18 parts, Fructus Schisandrae Chinensis 15 parts, 20 parts of Poria, Fructus Gardeniae 15 parts, the Radix Paeoniae Alba 15 parts, figured silk fabrics
Grass 10 parts, Folium Eucommiae 20 parts.
The preparation method of the Chinese medicine composition for the treatment of depressive neurosis, comprises the following steps:
1) Radix Curcumae, the Rhizoma Atractylodis Macrocephalae, Rhizoma et radix valerianae are taken, mixing, it is placed in volatile oil extractor, soaks, decompression distillation 1h, collects
Distillate, second distillation, ether extracts, and is dried, obtains volatile oil, Aqueous extracts and filtering residue standby；
2) by Medulla Junci, Folium Eucommiae, Radix Bupleuri, Poria and step 1) in filtering residue mixing, add 8 times amount water, decoct extraction 2
Secondary, each 1h, filters, discards medicinal residues, obtain Aqueous extracts；
3) Cortex Albiziae, Fructus Schisandrae Chinensis, Fructus Gardeniae, the Radix Paeoniae Alba are taken, mixing, add 8 times amount 70% alcohol heating reflux extraction 2 times, often
Secondary 1h, filters, obtains alcohol extract；
4) combining step 1) Aqueous extracts and volatile oil, step 2) in Aqueous extracts, step 3) alcohol extract, be concentrated to give leaching
Cream, is dried, is ground into medicated powder；
5) in medicated powder, add pharmaceutically acceptable carrier, be prepared as tablet.
Clinical practice
Case selection: select Factors of Depressive Patients 340 example made a definite diagnosis, wherein male 152 example, women 188 example, age
In 14-65 year, the mean age is 26 years old, is randomly divided into 2 groups, experimental group and matched group, often organizes each 170 examples, male 76 example, women
94 examples, the equal not statistically significant of difference (P ＜ 0.05) such as two groups of sexes, age, the state of an illness, courses of disease, there is comparability.
1, diagnostic criteria: 1. Chinese Spirit Obstacles classification and diagnostic criteria (CCMD-3)；2. Hamilton depression scale
(HAMD, 24) ＞ 20 points；3. symptom at least continues 2 weeks；4. get rid of and have organic disease, physical disease and psychoactive drug substance
Caused depression, there is the symptom such as auditory hallucination, vain hope, differentiates with schizophrenia in patient.
2, Therapeutic Method: experimental group be administered orally the embodiment of the present invention 1 preparation Chinese medicinal tablet, 2g/ sheet, three times a day, each 2
Grain；Matched group is administered orally imipramine 75mg, and three times a day, two groups for the treatment of cycle were for 4 courses for the treatment of, within 10 days, were 1 course for the treatment of.
Outcome measure: use HAMD and self rating depressive scale SDS before the treatment and after treatment each course for the treatment of terminate after respectively
Evaluate 1 time, after treating for 2 courses for the treatment of, evaluate untoward reaction with TESS, evaluation person each scale consistency check r=0.89-0.93；Press
HAMD deduction rate evaluation curative effect, >=75% is recovery from illness, and >=74%-25% is that effectively ＜ 25% is invalid；Blood, urine before and after treatment
Routine, Liver and kidney function and electrocardiogram, electroencephalogram respectively do once.
4, therapeutic effect: 150 examples of fully recovering in experimental group 170 example, effective 19 examples, invalid 1 example, total effective rate reaches 99.4%；
Matched group is fully recovered 138 examples, effective 24 examples, invalid 8 examples, total effective rate 95.3%, it can be seen that experimental group cure rate, the most effective
Rate is significantly better than that matched group.Before and after treatment, the inspection of Leukocyte Counts, hepatic and renal function and electroencephalogram has no significant change, real
Test group and untoward reaction does not occurs；Xerostomia, constipation, postural hypotension occur during treatment of control group, severe patient arrhythmia,
Disturbance of consciousness occurs.
Above example only in order to technical scheme to be described, is not intended to limit；Although with reference to previous embodiment
The present invention is described in detail, it will be understood by those within the art that: it still can be to aforementioned each enforcement
Technical scheme described in example is modified, or wherein portion of techniques feature is carried out equivalent；And these amendment or
Replace, do not make the essence of appropriate technical solution depart from the spirit and scope of various embodiments of the present invention technical scheme.
Claims (5)
1. the Chinese medicine composition treating depressive neurosis, it is characterised in that be made up of the raw material of following weight portion: wick
Grass 10-15 part, Cortex Albiziae 20-25 part, Rhizoma Atractylodis Macrocephalae 15-20 part, Radix Curcumae 13-18 part, Radix Bupleuri 13-18 part, Fructus Schisandrae Chinensis 15-20 part, Fu
Siberian cocklebur 15-20 part, Fructus Gardeniae 15-20 part, Radix Paeoniae Alba 10-15 part, Rhizoma et radix valerianae 10-15 part, Folium Eucommiae 15-20 part.
2. the Chinese medicine composition treating depressive neurosis as claimed in claim 1, it is characterised in that by following weight portion
Raw material is made: Medulla Junci 12 parts, Cortex Albiziae 21 parts, the Rhizoma Atractylodis Macrocephalae 17 parts, Radix Curcumae 15 parts, Radix Bupleuri 15 parts, Fructus Schisandrae Chinensis 18 parts, Poria 20
Part, Fructus Gardeniae 17 parts, the Radix Paeoniae Alba 14 parts, Rhizoma et radix valerianae 12 parts, Folium Eucommiae 16 parts.
3. the preparation method of the Chinese medicine composition for the treatment of depressive neurosis as claimed in claim 1 or 2, it is characterised in that
Comprise the following steps:
1) Radix Curcumae, the Rhizoma Atractylodis Macrocephalae, Rhizoma et radix valerianae are taken, mixing, it is placed in volatile oil extractor, soaks, decompression distillation 1h, collection evaporates
Liquid, second distillation, ether extracts, and is dried, obtains volatile oil, Aqueous extracts and filtering residue standby；
2) by Medulla Junci, Folium Eucommiae, Radix Bupleuri, Poria and step 1) in filtering residue mixing, add 8 times amount water, decoct and extract 2 times,
1h every time, filters, discards medicinal residues, obtain Aqueous extracts；
3) Cortex Albiziae, Fructus Schisandrae Chinensis, Fructus Gardeniae, the Radix Paeoniae Alba are taken, mixing, add 8 times amount 70% alcohol heating reflux and extract 2 times, each 1h,
Filter, obtain alcohol extract；
4) combining step 1) Aqueous extracts and volatile oil, step 2) in Aqueous extracts, step 3) alcohol extract, be concentrated to give extractum,
It is dried, is ground into medicated powder；
5) in medicated powder, add pharmaceutically acceptable carrier, be prepared as corresponding pharmaceutical dosage form.
4. the preparation method of the Chinese medicine composition for the treatment of depressive neurosis as claimed in claim 3, it is characterised in that described
Dosage form is tablet, granule, capsule or pill.
5. treat the Chinese medicine composition medicine as treatment depressive neurosis of depressive neurosis as claimed in claim 1 or 2
The application of the effective ingredient of thing.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106581238A (en) * | 2017-01-02 | 2017-04-26 | 佛山市腾瑞医药科技有限公司 | Traditional Chinese medicine composition for relaxing bowels and preparation method of traditional Chinese medicine composition |
| CN106581588A (en) * | 2017-01-29 | 2017-04-26 | 毛华养 | Medicine for treating depressive neurosis |
| CN107080785A (en) * | 2017-04-07 | 2017-08-22 | 云南龙发制药股份有限公司 | A kind of jatamans valeriana rhizome volatile oil antiseptic inclusion compound and preparation method thereof |
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|---|---|---|---|---|
| CN1579461A (en) * | 2003-08-07 | 2005-02-16 | 于水 | Anti-depression traditional medicinal composition and its preparation method |
| CN101204575A (en) * | 2007-12-20 | 2008-06-25 | 董建国 | Chinese traditional medicine composite for depressive neurosis, preparation method and application thereof |
| CN103285334A (en) * | 2013-06-25 | 2013-09-11 | 单翠红 | Prescription for treatment of depressive neurosis |
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2016
- 2016-08-10 CN CN201610653281.XA patent/CN106039238A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1579461A (en) * | 2003-08-07 | 2005-02-16 | 于水 | Anti-depression traditional medicinal composition and its preparation method |
| CN101204575A (en) * | 2007-12-20 | 2008-06-25 | 董建国 | Chinese traditional medicine composite for depressive neurosis, preparation method and application thereof |
| CN103285334A (en) * | 2013-06-25 | 2013-09-11 | 单翠红 | Prescription for treatment of depressive neurosis |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106581238A (en) * | 2017-01-02 | 2017-04-26 | 佛山市腾瑞医药科技有限公司 | Traditional Chinese medicine composition for relaxing bowels and preparation method of traditional Chinese medicine composition |
| CN106581588A (en) * | 2017-01-29 | 2017-04-26 | 毛华养 | Medicine for treating depressive neurosis |
| CN107080785A (en) * | 2017-04-07 | 2017-08-22 | 云南龙发制药股份有限公司 | A kind of jatamans valeriana rhizome volatile oil antiseptic inclusion compound and preparation method thereof |
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