CN106036914A - Sleep aiding health product and preparation method thereof - Google Patents
Sleep aiding health product and preparation method thereof Download PDFInfo
- Publication number
- CN106036914A CN106036914A CN201610391412.1A CN201610391412A CN106036914A CN 106036914 A CN106036914 A CN 106036914A CN 201610391412 A CN201610391412 A CN 201610391412A CN 106036914 A CN106036914 A CN 106036914A
- Authority
- CN
- China
- Prior art keywords
- sleep
- aminobutyric acid
- gamma
- preparation
- health care
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000036541 health Effects 0.000 title claims abstract description 35
- 238000002360 preparation method Methods 0.000 title abstract description 13
- 238000004519 manufacturing process Methods 0.000 title description 5
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 claims abstract description 62
- 229960003692 gamma aminobutyric acid Drugs 0.000 claims abstract description 33
- OGNSCSPNOLGXSM-UHFFFAOYSA-N (+/-)-DABA Natural products NCCC(N)C(O)=O OGNSCSPNOLGXSM-UHFFFAOYSA-N 0.000 claims abstract description 29
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims abstract description 12
- 229910021529 ammonia Inorganic materials 0.000 claims abstract description 6
- 238000000034 method Methods 0.000 claims abstract description 4
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 12
- 239000000843 powder Substances 0.000 claims description 12
- RANQPHKSRUUPKK-UHFFFAOYSA-N 3-O-[alpha-L-arabinofuranosyl-(1->2)-O-{beta-D-glucopyranosyl-(1->3)}-(alpha-L-arabinopyranosyl)]jujubogenin Natural products CC(C)=CC1CC(C)(O)C2C3CCC4C5(C)CCC(OC6OCC(O)C(OC7OC(CO)C(O)C(O)C7O)C6OC6OC(CO)C(O)C6O)C(C)(C)C5CCC4(C)C33COC2(C3)O1 RANQPHKSRUUPKK-UHFFFAOYSA-N 0.000 claims description 10
- 229930192286 jujuboside Natural products 0.000 claims description 10
- 239000012141 concentrate Substances 0.000 claims description 9
- 239000006166 lysate Substances 0.000 claims description 9
- 230000001954 sterilising effect Effects 0.000 claims description 9
- 238000004659 sterilization and disinfection Methods 0.000 claims description 9
- PXEDJBXQKAGXNJ-QTNFYWBSSA-L disodium L-glutamate Chemical compound [Na+].[Na+].[O-]C(=O)[C@@H](N)CCC([O-])=O PXEDJBXQKAGXNJ-QTNFYWBSSA-L 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 7
- 235000013923 monosodium glutamate Nutrition 0.000 claims description 7
- 229940073490 sodium glutamate Drugs 0.000 claims description 7
- 102000008214 Glutamate decarboxylase Human genes 0.000 claims description 6
- 108091022930 Glutamate decarboxylase Proteins 0.000 claims description 6
- 238000001035 drying Methods 0.000 claims description 6
- 239000012137 tryptone Substances 0.000 claims description 6
- 235000018102 proteins Nutrition 0.000 claims description 5
- 102000004169 proteins and genes Human genes 0.000 claims description 5
- 108090000623 proteins and genes Proteins 0.000 claims description 5
- 108090000790 Enzymes Proteins 0.000 claims description 4
- 102000004190 Enzymes Human genes 0.000 claims description 4
- 238000002386 leaching Methods 0.000 claims description 4
- 239000002994 raw material Substances 0.000 claims description 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 3
- 241000186660 Lactobacillus Species 0.000 claims description 3
- 241000219100 Rhamnaceae Species 0.000 claims description 3
- 241000209140 Triticum Species 0.000 claims description 3
- 235000021307 Triticum Nutrition 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 3
- 235000015278 beef Nutrition 0.000 claims description 3
- 230000003197 catalytic effect Effects 0.000 claims description 3
- 238000000855 fermentation Methods 0.000 claims description 3
- 230000004151 fermentation Effects 0.000 claims description 3
- 239000008103 glucose Substances 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 210000000582 semen Anatomy 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- 238000003860 storage Methods 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 2
- 229940039696 lactobacillus Drugs 0.000 claims description 2
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 claims description 2
- 239000011593 sulfur Substances 0.000 claims description 2
- 229910052717 sulfur Inorganic materials 0.000 claims description 2
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 claims 2
- 230000000694 effects Effects 0.000 abstract description 13
- 230000006870 function Effects 0.000 abstract description 10
- 239000008280 blood Substances 0.000 abstract description 5
- 210000004369 blood Anatomy 0.000 abstract description 5
- 210000005036 nerve Anatomy 0.000 abstract description 5
- 230000036772 blood pressure Effects 0.000 abstract description 4
- 230000028327 secretion Effects 0.000 abstract description 4
- 208000024827 Alzheimer disease Diseases 0.000 abstract description 3
- 208000019901 Anxiety disease Diseases 0.000 abstract description 3
- 206010003210 Arteriosclerosis Diseases 0.000 abstract description 3
- 208000035985 Body Odor Diseases 0.000 abstract description 3
- 206010039966 Senile dementia Diseases 0.000 abstract description 3
- 206010040904 Skin odour abnormal Diseases 0.000 abstract description 3
- 230000036506 anxiety Effects 0.000 abstract description 3
- 208000011775 arteriosclerosis disease Diseases 0.000 abstract description 3
- 206010003549 asthenia Diseases 0.000 abstract description 3
- 230000009286 beneficial effect Effects 0.000 abstract description 3
- 230000001914 calming effect Effects 0.000 abstract description 3
- 230000006872 improvement Effects 0.000 abstract description 3
- 230000037356 lipid metabolism Effects 0.000 abstract description 3
- 230000009759 skin aging Effects 0.000 abstract description 3
- 239000004615 ingredient Substances 0.000 abstract 2
- 102000018997 Growth Hormone Human genes 0.000 abstract 1
- 108010051696 Growth Hormone Proteins 0.000 abstract 1
- 208000007443 Neurasthenia Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 230000018109 developmental process Effects 0.000 abstract 1
- 239000000122 growth hormone Substances 0.000 abstract 1
- 210000000653 nervous system Anatomy 0.000 abstract 1
- 235000008935 nutritious Nutrition 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 abstract 1
- 229930182490 saponin Natural products 0.000 abstract 1
- 150000007949 saponins Chemical class 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 description 9
- 210000004958 brain cell Anatomy 0.000 description 6
- 244000269722 Thea sinensis Species 0.000 description 5
- NDVRKEKNSBMTAX-BTVCFUMJSA-N (2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanal;phosphoric acid Chemical compound OP(O)(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O NDVRKEKNSBMTAX-BTVCFUMJSA-N 0.000 description 4
- 108090000371 Esterases Proteins 0.000 description 4
- 206010033557 Palpitations Diseases 0.000 description 4
- 230000004060 metabolic process Effects 0.000 description 4
- 235000016709 nutrition Nutrition 0.000 description 4
- 108090000765 processed proteins & peptides Proteins 0.000 description 4
- 230000035900 sweating Effects 0.000 description 4
- 235000009569 green tea Nutrition 0.000 description 3
- 239000005556 hormone Substances 0.000 description 3
- 229940088597 hormone Drugs 0.000 description 3
- 230000001976 improved effect Effects 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 235000013616 tea Nutrition 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 2
- 208000036119 Frailty Diseases 0.000 description 2
- 241000228347 Monascus <ascomycete fungus> Species 0.000 description 2
- 208000027089 Parkinsonian disease Diseases 0.000 description 2
- 206010034010 Parkinsonism Diseases 0.000 description 2
- 208000001431 Psychomotor Agitation Diseases 0.000 description 2
- 206010038743 Restlessness Diseases 0.000 description 2
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 2
- 206010043458 Thirst Diseases 0.000 description 2
- OIPILFWXSMYKGL-UHFFFAOYSA-N acetylcholine Chemical compound CC(=O)OCC[N+](C)(C)C OIPILFWXSMYKGL-UHFFFAOYSA-N 0.000 description 2
- 229960004373 acetylcholine Drugs 0.000 description 2
- 229940024606 amino acid Drugs 0.000 description 2
- 235000001014 amino acid Nutrition 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 235000021329 brown rice Nutrition 0.000 description 2
- 230000019522 cellular metabolic process Effects 0.000 description 2
- 230000002490 cerebral effect Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 230000009429 distress Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000004153 glucose metabolism Effects 0.000 description 2
- 206010022437 insomnia Diseases 0.000 description 2
- 238000002372 labelling Methods 0.000 description 2
- 239000002609 medium Substances 0.000 description 2
- 230000007514 neuronal growth Effects 0.000 description 2
- 102000039446 nucleic acids Human genes 0.000 description 2
- 108020004707 nucleic acids Proteins 0.000 description 2
- 150000007523 nucleic acids Chemical class 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 229920001184 polypeptide Polymers 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 239000011573 trace mineral Substances 0.000 description 2
- 235000013619 trace mineral Nutrition 0.000 description 2
- 230000004102 tricarboxylic acid cycle Effects 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 150000003722 vitamin derivatives Chemical class 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 206010065559 Cerebral arteriosclerosis Diseases 0.000 description 1
- 206010008132 Cerebral thrombosis Diseases 0.000 description 1
- 206010012289 Dementia Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 201000001429 Intracranial Thrombosis Diseases 0.000 description 1
- 241001300479 Macroptilium Species 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
- 244000131316 Panax pseudoginseng Species 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 208000009205 Tinnitus Diseases 0.000 description 1
- 230000000049 anti-anxiety effect Effects 0.000 description 1
- 239000002249 anxiolytic agent Substances 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000003925 brain function Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 206010015037 epilepsy Diseases 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 230000000147 hypnotic effect Effects 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 201000005851 intracranial arteriosclerosis Diseases 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 229940099596 manganese sulfate Drugs 0.000 description 1
- 235000007079 manganese sulphate Nutrition 0.000 description 1
- 239000011702 manganese sulphate Substances 0.000 description 1
- SQQMAOCOWKFBNP-UHFFFAOYSA-L manganese(II) sulfate Chemical compound [Mn+2].[O-]S([O-])(=O)=O SQQMAOCOWKFBNP-UHFFFAOYSA-L 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 229910000403 monosodium phosphate Inorganic materials 0.000 description 1
- 235000019799 monosodium phosphate Nutrition 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 239000002858 neurotransmitter agent Substances 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000005062 synaptic transmission Effects 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention discloses a sleep aiding health product and a preparation method thereof. The sleep aiding health product is characterized by being prepared from the following ingredients in percentage by weight: 80% of gamma aminobutyric acid and 20% of spine date seed saponin. The preparation method comprises preparation steps as following: 1, preparation of the gamma aminobutyric acid; 2, preparation of the sleep aiding health product. The sleep aiding health product has the beneficial effects of calming nerves, resisting anxiety, reducing blood pressure and promoting growth hormone secretion of children, plays a nutritious role in a development process of the nervous system, has remarkable improvement effect on various symptoms such as Parkinson's disease, senile dementia, neurasthenia and the like, and can effectively reduce blood ammonia; the ingredient gamma aminobutyric acid contained in the sleep aiding health product further has functions of preventing skin aging, eliminating body odor, improving lipid metabolism, preventing arteriosclerosis, efficiently reducing weight and the like.
Description
Technical field
The invention belongs to health product technology field, more specifically a kind of sleep-assistant health care product and preparation method.
Background technology
γ-aminobutyric acid (GABA), is distributed widely in animal and plant body.The kind of plant such as Macroptilium, ginseng genus, Chinese herbal medicine etc.
Son, rhizome and tissue fluid all contain GABA, molecular formula: C4H9NO2, molecular weight: 103.1.In animal body, GABA is almost
Existing only in nervous tissue, the content in its mesencephalic tissue is about 0.1-0.6mg/ gram of tissue, and immunological investigation shows, its
The region that concentration is the highest is black substance in brain.GABA is to study the most deep a kind of important inhibitory neurotransmitter at present,
It participates in multiple metabolic activity, has the highest physiologically active, has neurotransmission, improves brain function, hypermnesis, anti-Jiao
Consider, treatment epilepsy, Control of asthma, regulation hormone secretion, prevent obesity, promote reproduction, activate Liver and kidney, to improve neurocyte old
Dementia, alleviate cerebral thrombosis, alleviate cerebral arteriosclerosis cause headache, alleviate the physiological functions such as tinnitus, be widely used in food,
The fields such as medicine, cosmetics and feedstuff.
The patent of invention of China's Patent No. 201510943689.6 discloses a kind of health care rich in γ-aminobutyric acid
Scented tea, its constituent and parts by weight are as follows: monascus M315 ~ 20；Green tea 45 ~ 50；Brown rice 18 ~ 25；Sodium glutamate 2 ~
4 ；Sodium dihydrogen phosphate 0.2 ~ 0.7；Rhizoma Dioscoreae 8 ~ 12.The present invention is rich in the health care scented tea of γ-aminobutyric acid, with generally acknowledge at present
Safety bacterial strain monascus is fermented bacterium, with commercially available green tea and brown rice as culture medium raw material, it is thus achieved that rich in γ-amino fourth
The tea-drinking of the functional components such as acid, improves the value of green tea, has saved social resources, has effectively improved and has worked as
The nutritive value of the upper tea beverage of modern society and health care.
The health product containing γ-aminobutyric acid of prior art, its function many emphasis nourishing healthy, the rest to people is slept
Sleeping and do not promote health-care effect, and current, owing to people are busy with one's work, having a rest, it is prior to may often be such that, have a rest bad also simultaneously
Can affect the healthy of people, compare nourishing healthy, the health care of hypnotic is more important.
Summary of the invention
It is an object of the invention to provide a kind of sleep-assistant health care product and preparation method, sleep-assistant health care product have calm neural, anti-
Anxiety, reduce blood pressure, promote the effect of people's sleep.
For solving above-mentioned technical problem, the technical solution adopted in the present invention is: a kind of sleep-assistant health care product and preparation method,
The each composition and the percentage by weight that it is characterized in that described sleep-assistant health care product be: gamma-aminobutyric acid 80%, jujuboside
20%；Its preparation process is as follows:
1, gamma-aminobutyric acid is prepared:
1. the yeast that weight ratio is 3% is soaked powder, the tryptone of 3%, the glucose of 3%, the sodium glutamate of 0.2%, the sulfur of 0.06%
Acid manganese, 90.74% pure water mixing, dissolve, obtain lysate；
2. lysate step 1. prepared is sent into sterilization tank and is carried out heat sterilization, and temperature controls at 120 DEG C, continues 20 minutes；
3. the lysate after step 2. heat sterilization is sent into fermentation tank, and add appropriate lactobacillus and ferment, send out
Ferment temperature controls at 35～37 DEG C, and the time keeps 120 hours, and keeps the concentration of sodium glutamate, through glutamic acid decarboxylase organized enzyme
Catalytic action, make glutamic acid decarboxylase prepare gamma-aminobutyric acid solution；
4. gamma-aminobutyric acid solution concentrate drying step 3. prepared, prepares gamma-aminobutyric acid powder；
2, sleep-assistant health care product are prepared:
By weight, the gamma-aminobutyric acid 80% that 4. step of learning from else's experience prepares, add jujuboside 20% and mix, stir,
I.e. preparing sleep-assistant health care product, subpackage is put in storage.
Described jujuboside, for the extract of the seed of Rhamnaceae plant Ziziphi Spinosae, have nourishing the liver, mind calming, calm the nerves, arresting sweating
Effect, restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, excessive thirst, sweating due to debility are had preferable curative effect.
Described yeast leaching powder, for dusty yeast extractum, be with Semen Maydis, wheat protein bakery yeast as raw material, through self-dissolving,
Enzymolysis, concentrate, the biological medium that technique is made such as be dried, rich in proteins, aminoacid, peptide, polypeptide, nucleic acid, vitamin and
The nutritional labelings such as trace element.
Described tryptone, is through trypsinization, the buff powder of concentrate drying with fresh beef and Os Bovis seu Bubali.
The invention has the beneficial effects as follows that sleep-assistant health care product have calm nerve, anxiety, reduce blood pressure, promote children growth
The effect of hormone secretion, has Nutrition in neural growth course, to parkinsonism, senile dementia, god
It is significantly improved effect through the various disease conditions tool such as weak, can effectively reduce blood ammonia.
Sleep-assistant health care product of the present invention can improve the activity of glucose phosphate esterase, makes brain cell activity vigorous, can promote
The metabolism of cerebral tissue and recovery function of brain cell, improve nervous function, improve brain vigor.Contained gamma-aminobutyric acid can enter
Enter tricarboxylic acid cycle in brain, promote brain cell metabolism, the activity of glucose phosphate esterase when simultaneously can also improve glucose metabolism,
Increasing the generation of acetylcholine, expansion blood vessel increases blood flow, and reduces blood ammonia, promote the metabolism of brain, recovers brain thin
Born of the same parents' function.
Gamma-aminobutyric acid composition contained by sleep-assistant health care product of the present invention also have prevent skin aging, eliminate body odor, improvement
Lipid metabolism, prevents the functions such as arteriosclerosis high-efficient fat reducing.
Detailed description of the invention:
Further illustrate the present invention below in conjunction with embodiment, but embodiment is only that the explanation present invention rather than carries out it
Limit.
Embodiment:
Prepare 1000 grams of sleep-assistant health care product, need gamma-aminobutyric acid 800 grams, jujuboside 200 grams；Its preparation process is as follows:
1,800 grams of gamma-aminobutyric acid of preparation:
1. by yeast that weight is 24000.00 grams leaching powder, the tryptone of 24000.00 grams, the glucose of 24000.00 grams,
The sodium glutamate of 1600.00 grams, the manganese sulfate of 48.00 grams, 7259.20 grams of pure water mixing, dissolve, obtain lysate；
2. lysate step 1. prepared is sent into sterilization tank and is carried out heat sterilization, and temperature controls at 120 DEG C, continues 20 minutes；
3. the lysate after step 2. heat sterilization is sent into fermentation tank, and add 10 grams of lactobacilluss and ferment, send out
Ferment temperature controls at 35～37 DEG C, and the time keeps 120 hours, and keeps the concentration of sodium glutamate, through glutamic acid decarboxylase organized enzyme
Catalytic action, make glutamic acid decarboxylase prepare gamma-aminobutyric acid solution；
4. the gamma-aminobutyric acid solution concentrate drying 3. step prepared, even 800 or gram gamma-aminobutyric acid powder；
2, sleep-assistant health care product are prepared:
Take the gamma-aminobutyric acid 800 grams that 4. above-mentioned steps prepares, add jujuboside 200 grams and mix, stir,
I.e. preparing sleep-assistant health care product, subpackage is put in storage.
Described jujuboside, for the extract of the seed of Rhamnaceae plant Ziziphi Spinosae, have nourishing the liver, mind calming, calm the nerves, arresting sweating
Effect, restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, excessive thirst, sweating due to debility are had preferable curative effect.
Described yeast leaching powder, for dusty yeast extractum, be with Semen Maydis, wheat protein bakery yeast as raw material, through self-dissolving,
Enzymolysis, concentrate, the biological medium that technique is made such as be dried, rich in proteins, aminoacid, peptide, polypeptide, nucleic acid, vitamin and
The nutritional labelings such as trace element.
Described tryptone, is through trypsinization, the buff powder of concentrate drying with fresh beef and Os Bovis seu Bubali.
Described sleep-assistant health care product index is as follows: gamma-aminobutyric acid content >=70%, jujuboside content >=20%, moisture
≤ 10%, ash≤10%.
The invention has the beneficial effects as follows that sleep-assistant health care product have calm nerve, anxiety, reduce blood pressure, promote children growth
The effect of hormone secretion, has Nutrition in neural growth course, to parkinsonism, senile dementia, god
It is significantly improved effect through the various disease conditions tool such as weak, can effectively reduce blood ammonia.
Sleep-assistant health care product of the present invention can improve the activity of glucose phosphate esterase, makes brain cell activity vigorous, can promote
The metabolism of cerebral tissue and recovery function of brain cell, improve nervous function, improve brain vigor.Contained gamma-aminobutyric acid can enter
Enter tricarboxylic acid cycle in brain, promote brain cell metabolism, the activity of glucose phosphate esterase when simultaneously can also improve glucose metabolism,
Increasing the generation of acetylcholine, expansion blood vessel increases blood flow, and reduces blood ammonia, promote the metabolism of brain, recovers brain thin
Born of the same parents' function.
Gamma-aminobutyric acid composition contained by sleep-assistant health care product of the present invention also have prevent skin aging, eliminate body odor, improvement
Lipid metabolism, prevents the functions such as arteriosclerosis high-efficient fat reducing.
Claims (1)
1. sleep-assistant health care product, is characterized in that each composition of described sleep-assistant health care product and percentage by weight are: gamma ammonia
Base butanoic acid 80%, jujuboside 20%；Described sleep-assistant health care product use following steps to prepare:
1), gamma-aminobutyric acid is prepared,
1. the yeast that weight ratio is 3% is soaked powder, the tryptone of 3%, the glucose of 3%, the sodium glutamate of 0.2%, the sulfur of 0.06%
Acid manganese, 90.74% pure water mixing, dissolve, obtain lysate；
2. lysate step 1. prepared is sent into sterilization tank and is carried out heat sterilization, and temperature controls at 120 DEG C, continues 20 minutes；
3. the lysate after step 2. heat sterilization is sent into fermentation tank, and add appropriate lactobacillus and ferment, send out
Ferment temperature controls at 35～37 DEG C, and the time keeps 120 hours, and keeps the concentration of sodium glutamate, through glutamic acid decarboxylase organized enzyme
Catalytic action, make glutamic acid decarboxylase prepare gamma-aminobutyric acid solution；
4. gamma-aminobutyric acid solution concentrate drying step 3. prepared, prepares gamma-aminobutyric acid powder；
2), sleep-assistant health care product are prepared,
By weight, the gamma-aminobutyric acid 80% that 4. step of learning from else's experience prepares, add jujuboside 20% and mix, stirring is all
Even, i.e. prepare sleep-assistant health care product, subpackage is put in storage；
Described jujuboside, for the extract of the seed of Rhamnaceae plant Ziziphi Spinosae；
Described yeast leaching powder, for dusty yeast extractum, is with Semen Maydis, wheat protein bakery yeast as raw material, through self-dissolving, enzyme
Solve, concentrate, the biological medium that technique is made such as be dried；
Described tryptone, is through trypsinization, the buff powder of concentrate drying with fresh beef and Os Bovis seu Bubali.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610391412.1A CN106036914A (en) | 2016-06-06 | 2016-06-06 | Sleep aiding health product and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610391412.1A CN106036914A (en) | 2016-06-06 | 2016-06-06 | Sleep aiding health product and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106036914A true CN106036914A (en) | 2016-10-26 |
Family
ID=57169586
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610391412.1A Pending CN106036914A (en) | 2016-06-06 | 2016-06-06 | Sleep aiding health product and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106036914A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107412369A (en) * | 2017-07-25 | 2017-12-01 | 云南彝药生物科技有限公司 | A kind of sanchi flower sleeping Pharmaceutical composition |
| CN108669386A (en) * | 2018-05-20 | 2018-10-19 | 刘振亚 | A kind of drink formula and preparation method thereof promoting sleep |
| CN112931865A (en) * | 2021-03-29 | 2021-06-11 | 山东百德生物科技有限公司 | Edible amino acid enzyme rich in gamma-aminobutyric acid and preparation method thereof |
| CN114081185A (en) * | 2021-04-23 | 2022-02-25 | 程新 | Gamma-aminobutyric acid detection method and composition for improving sleep and resisting anxiety |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101340823A (en) * | 2005-12-26 | 2009-01-07 | Cj第一制糖株式会社 | Manufacturing method for fermented soybeans having increased gamma-aminobutyric acid content |
| CN101389751A (en) * | 2006-02-21 | 2009-03-18 | 龟甲万株式会社 | Lactic acid bacterium capable of producing gamma-aminobutyric acid |
| CN101880644A (en) * | 2010-05-28 | 2010-11-10 | 广州立达尔生物科技有限公司 | Liquid submerged fermentation method for lactobacillus gasseri |
| CN104187613A (en) * | 2014-07-29 | 2014-12-10 | 胡安然 | Total-nutrient formulated food for patients with insomnia |
| CN105029429A (en) * | 2015-06-17 | 2015-11-11 | 青岛海百合生物技术有限公司 | Food additive enriched by gamma-aminobutyric acid and preparation method for food additive |
| CN105077477A (en) * | 2015-08-12 | 2015-11-25 | 北京晚安科技有限责任公司 | Sleeping-aid beverage |
-
2016
- 2016-06-06 CN CN201610391412.1A patent/CN106036914A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101340823A (en) * | 2005-12-26 | 2009-01-07 | Cj第一制糖株式会社 | Manufacturing method for fermented soybeans having increased gamma-aminobutyric acid content |
| CN101389751A (en) * | 2006-02-21 | 2009-03-18 | 龟甲万株式会社 | Lactic acid bacterium capable of producing gamma-aminobutyric acid |
| CN101880644A (en) * | 2010-05-28 | 2010-11-10 | 广州立达尔生物科技有限公司 | Liquid submerged fermentation method for lactobacillus gasseri |
| CN104187613A (en) * | 2014-07-29 | 2014-12-10 | 胡安然 | Total-nutrient formulated food for patients with insomnia |
| CN105029429A (en) * | 2015-06-17 | 2015-11-11 | 青岛海百合生物技术有限公司 | Food additive enriched by gamma-aminobutyric acid and preparation method for food additive |
| CN105077477A (en) * | 2015-08-12 | 2015-11-25 | 北京晚安科技有限责任公司 | Sleeping-aid beverage |
Non-Patent Citations (1)
| Title |
|---|
| 顾金刚: "《中国农业菌种目录大全》", 31 January 2014, 中国农业科学技术出版社 * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107412369A (en) * | 2017-07-25 | 2017-12-01 | 云南彝药生物科技有限公司 | A kind of sanchi flower sleeping Pharmaceutical composition |
| CN108669386A (en) * | 2018-05-20 | 2018-10-19 | 刘振亚 | A kind of drink formula and preparation method thereof promoting sleep |
| CN112931865A (en) * | 2021-03-29 | 2021-06-11 | 山东百德生物科技有限公司 | Edible amino acid enzyme rich in gamma-aminobutyric acid and preparation method thereof |
| CN114081185A (en) * | 2021-04-23 | 2022-02-25 | 程新 | Gamma-aminobutyric acid detection method and composition for improving sleep and resisting anxiety |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106562162B (en) | Malus spectabilis probiotic fermented drink and preparation method thereof | |
| CN106036914A (en) | Sleep aiding health product and preparation method thereof | |
| CN103250865A (en) | Preparation method of peanut polypeptide | |
| CN103387899A (en) | Black tea wine and production method thereof | |
| CN105962369A (en) | Method for preparing lactobacillus fermentation liquor from black tea enzymatic hydrolysate | |
| CN104687202B (en) | A kind of manufacture method of Fructus Musae fermented beverage | |
| CN100413424C (en) | Health-caring nutrition powder | |
| CN103976205B (en) | Endocrine fruit jelly of a kind of improvement and preparation method thereof | |
| CN107361270A (en) | A kind of preparation method of jujube enzyme beverage | |
| CN113186066A (en) | SOD wine capable of preserving health and tonifying kidney and preparation method thereof | |
| CN106418067B (en) | health beverage for supplementing physical strength and relieving fatigue | |
| CN106900887A (en) | A kind of children educational tea oil | |
| CN103704351A (en) | Pawpaw bovine colostrum powder and preparation method thereof | |
| CN109845863A (en) | A kind of tree peony coffee and preparation method thereof supplementing 3 nutrient of omega | |
| CN105232441A (en) | Preparing method of enzyme speckle removing cream | |
| CN107822122A (en) | A kind of rhodiola root ferment and preparation method thereof | |
| CN108936631A (en) | A kind of chlorella pyrenoidosa piece and preparation method thereof | |
| CN101889685B (en) | Natural plant health care product and preparation method thereof | |
| CN104509862A (en) | All-lotus-seed-peptide nutrition and preparation method thereof | |
| CN107373526A (en) | A kind of liquid preparation method of the instant dish of ferment | |
| CN106857861A (en) | A kind of production method of red plants protein beverage | |
| CN105962368A (en) | Preparation method of dendrobium officinale fermentation liquid | |
| CN106036886A (en) | Gingko enzyme and preparation method thereof | |
| CN108522839A (en) | A kind of fermented feed and preparation method thereof of enhancing goat immune power | |
| CN109874960A (en) | A kind of preparation process of Bee Pollen pollen crystalline substance |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20161026 |
|
| RJ01 | Rejection of invention patent application after publication |