CN1060352C

CN1060352C - Blood-fat reducing medicine and preparing process thereof

Info

Publication number: CN1060352C
Application number: CN96102687A
Authority: CN
Inventors: 袁克兴; 郑军
Original assignee: Individual
Current assignee: Individual
Priority date: 1996-02-08
Filing date: 1996-02-08
Publication date: 2001-01-10
Anticipated expiration: 2016-02-08
Also published as: CN1156601A

Abstract

The present invention relates to a medicine for treating the diseases of hyperlipemia, fatty liver, adiposis, atherosclerosis of arteries blood vessel, coronary heart disease, apoplexy, etc. and a preparation method of the medicine. The medicine comprises the following components of giant knotweed rhizome, curcuma roots, citron peel, lotus leaves, raw haws, raw astragalus roots, schisandra fruits, fried white atractylodes rhizome, glossy privet fruits, broomrape, epimedium, rhubarb horsetail and water plantain through the processes of crushing, mixing, decoction and concentration. The present invention has the efficacy of strengthening a liver and a spleen, tonifying Qi of kidneys and activating blood circulation to dissipate blood stasis. The present invention also has the curative effects of reducing the contents of cholesterol and triglyceride in blood, increasing the content of high-density lipoprotein, accelerating lipid metabolism and slowing down the speed of angiosclerosis.

Description

Lipid lowerers and preparation method thereof

The present invention discloses a kind of Chinese patent medicine for the treatment of diseases such as hyperlipemia, fatty liver, obesity, arteries is atherosis and preparation method thereof.

Hyperlipemia is meant a kind of pathological state when one or more components and concentrations surpass arm's length standard in the blood plasma matter.Blood fat mainly is made up of cholesterol, glyceride, phospholipid, free fatty etc.In the clinical practice, finding that cardiovascular and cerebrovascular disease is many usually to deposit a large amount of lipids in the speckle of patient vessel's wall because of arteriosclerosis causes, illustrate that hyperlipemia is not only the key factor of facilitating arteriosclerosis to develop, also is the pathologic basis of cardiovascular and cerebrovascular disease.Defectives such as therefore, medical circle is generally built consensus, and promptly can reduce the hardened sickness rate of artery by reducing hyperlipidemia, reaches the purpose of treatment hyperlipemia, and the Western medicine blood fat reducing exists poor stability, and recurrence, and side effect easily is bigger.

The object of the present invention is to provide a kind of traditional Chinese medical science medicine and preparation method thereof, the content by cholesterol and triglyceride in the reduction blood increases its hdl concentration, quickens lipid metabolism, and sclerosis of blood vessels speed slows down.

The present invention is the purpose that reaches the treatment hyperlipemia by the Chinese medicine that adopts following raw materials according: Rhizoma Polygoni Cuspidati 6～8%, Radix Curcumae 6～8%, Pericarpium Citri 6～8%, Folium Nelumbinis 4～6%, Rhizoma Alismatis 4～6%, Fructus Crataegi 12～15%, Radix Astragali 8～10%, Pericarpium citri reticuatae chachiensis 3～6%, Fructus Amomi 3～5%, Fructus Schisandrae Chinensis 6～8%, Rhizoma Atractylodis Macrocephalae (parched) 6～10%, Fructus Ligustri Lucidi 6～10%, Herba Cistanches 6～8%, Herba Epimedii 6～10%, Radix Et Rhizoma Rhei 1.5～4%.

Above-mentioned preparation method of Chinese medicine may further comprise the steps: earlier Rhizoma Polygoni Cuspidati, Radix Curcumae, Rhizoma Alismatis, Fructus Crataegi, Radix Astragali, Rhizoma Atractylodis Macrocephalae (parched), Radix Et Rhizoma Rhei are mixed, be ground into fine powder, again remaining medicine is decocted with water secondary, merging filtrate, be concentrated into the 1 gram content that every milliliter of concentrated solution is equivalent to crude drug in whole, with above-mentioned fine powder mixing after drying, this fine powder is further pulverized milled then, sieve; Fine powder is with water pill or incapsulate.

Fat reducing pill provided by the present invention or capsule are pure Chinese medicinal preparation, show through clinical use, have the liver soothing and the spleen invigorating, tonify Qi of the kidney, the effect of blood circulation promoting and blood stasis dispelling, can reduce the content of cholesterol and triglyceride in the blood, increase its hdl concentration; Blood viscosity lowering, the lipidosis of removing blood vessel wall improves blood circulation, quickens lipid metabolism, and sclerosis of blood vessels speed slows down.

Embodiment

Take by weighing former medicine by following component and content thereof: Rhizoma Polygoni Cuspidati 6～8%, Radix Curcumae 6～8%, Pericarpium Citri 6～8%, Folium Nelumbinis 4～6%, Rhizoma Alismatis 4～6%, %, Fructus Crataegi 12～15%, Radix Astragali 8～10%, Pericarpium citri reticuatae chachiensis 3～6%, Fructus Amomi 3～5%, Fructus Schisandrae Chinensis 6～8%, Rhizoma Atractylodis Macrocephalae (parched) 6～10%, Fructus Ligustri Lucidi 6～10%, Herba Cistanches 6～8%, Herba Epimedii 6～10%, Radix Et Rhizoma Rhei 1.5～4%.

Earlier Rhizoma Polygoni Cuspidati, Radix Curcumae, Rhizoma Alismatis, Fructus Crataegi, Radix Astragali, Rhizoma Atractylodis Macrocephalae (parched), Radix Et Rhizoma Rhei are mixed, be ground into fine powder, again remaining medicine is decocted with water secondary, merging filtrate, be concentrated into to a certain degree, concentrating degree is grasped the 1 gram content that is equivalent to crude drug in whole at every milliliter of concentrated solution, with above-mentioned fine powder and concentrated solution mixing after drying, further pulverize then and mill, sieve; Make ball or capsule gets final product.

Rhizoma Polygoni Cuspidati in the above raw material, Radix Astragali, Herba Cistanches, Fructus Ligustri Lucidi four flavor owners want component, all belong to necessary component outward and remove Pericarpium citri reticuatae chachiensis, Fructus Amomi, in the medication preparation process, its color is gradually changed by yellowish → deep yellow → brown, fragrant odour, suffering, hardship, little sweet.

Has optimum curative effect through clinical use following component of proof and content;

Rhizoma Polygoni Cuspidati 12g, Radix Curcumae 12g, Pericarpium Citri 12g, Folium Nelumbinis 10g, Rhizoma Alismatis 10g, Fructus Crataegi 20g, Radix Astragali 15g, Pericarpium citri reticuatae chachiensis 10g, Fructus Amomi 6g, Fructus Schisandrae Chinensis 10g, Rhizoma Atractylodis Macrocephalae (parched) 12g, Fructus Ligustri Lucidi 12g, Herba Cistanches 10g, Herba Epimedii 10g, Radix Et Rhizoma Rhei 4g.

The above institute weight that provides adopts content to represent:

Rhizoma Polygoni Cuspidati 7.3%, Radix Curcumae 7.3%, Pericarpium Citri 7.3%, Folium Nelumbinis 6%, Rhizoma Alismatis 6%, Fructus Crataegi 12.1%, Radix Astragali 9.2%, Pericarpium citri reticuatae chachiensis 6%, Fructus Amomi 3.6%, Fructus Schisandrae Chinensis 6%, Rhizoma Atractylodis Macrocephalae (parched) 7.3%, Fructus Ligustri Lucidi 7.3%, Herba Cistanches 6%, Herba Epimedii 6%, Radix Et Rhizoma Rhei 2.6%.

With the medicine of above-mentioned content according to described preparation method via pulverizing, mix, decoct, concentrate encapsulated or making ball.

Clinical observation, after the course of treatment (three months) of taking medicine, TG descends and reaches 75%, and TCH descends and reaches 60%, and HDL-CH rises 75%; Fatty liver disappears; 80% above patient take medicine back xerostomia hardship, uncomfortable in chest, weak, breathe hard, receive food, defecation, picture of the tongue, pulse condition and all significantly improve, the present invention is a pure Chinese medicinal preparation, has no side effect.

Claims

1. lipid lowerers, it is made by following raw materials according: Rhizoma Polygoni Cuspidati 6～8%, Radix Curcumae 6～8%, Pericarpium Citri 6～8%, Folium Nelumbinis 4～6%, Rhizoma Alismatis 4～6%, Fructus Crataegi 12～15%, Radix Astragali 8～10%, Pericarpium citri reticuatae chachiensis 3～6%, Fructus Amomi 3～5%, Fructus Schisandrae Chinensis 6～8%, Rhizoma Atractylodis Macrocephalae (parched) 6～1 0%, Fructus Ligustri Lucidi 6～1 0%, Herba Cistanches 6～8%, Herba Epimedii 6～10%, Radix Et Rhizoma Rhei 1.5～4%, above raw material forms through pulverizing, mix, decoct, concentrating.

2. method for preparing the described lipid lowerers of claim 1, comprise the following steps: earlier Rhizoma Polygoni Cuspidati, Radix Curcumae, Rhizoma Alismatis, Fructus Crataegi, Radix Astragali, Rhizoma Atractylodis Macrocephalae (parched), Radix Et Rhizoma Rhei to be mixed, be ground into fine powder, again remaining medicine is decocted with water secondary, merging filtrate is concentrated into the 1 gram content that every milliliter of concentrated solution is equivalent to crude drug in whole, with above-mentioned fine powder mixing after drying, then this fine powder is further pulverized and milled, sieve; Fine powder is with water pill or incapsulate.