CN106029078A - 使用基于藻酸的抗微生物化合物抑制炎症和疾病的组合物和方法 - Google Patents

使用基于藻酸的抗微生物化合物抑制炎症和疾病的组合物和方法 Download PDF

Info

Publication number
CN106029078A
CN106029078A CN201480075975.9A CN201480075975A CN106029078A CN 106029078 A CN106029078 A CN 106029078A CN 201480075975 A CN201480075975 A CN 201480075975A CN 106029078 A CN106029078 A CN 106029078A
Authority
CN
China
Prior art keywords
acid
alginic acid
alginic
composition
molecular weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201480075975.9A
Other languages
English (en)
Chinese (zh)
Inventor
W·格斯里
盖瑞·哈恩
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evofem Inc
Original Assignee
Evofem Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53403777&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN106029078(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Evofem Inc filed Critical Evofem Inc
Priority to CN202210078304.4A priority Critical patent/CN114452298A/zh
Publication of CN106029078A publication Critical patent/CN106029078A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/02—Contraceptive devices; Pessaries; Applicators therefor for use by males
    • A61F6/04—Condoms, sheaths or the like, e.g. combined with devices protecting against contagion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/065—Condom-like devices worn by females
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/734—Alginic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body
    • A61M35/003—Portable hand-held applicators having means for dispensing or spreading integral media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201480075975.9A 2013-12-19 2014-12-19 使用基于藻酸的抗微生物化合物抑制炎症和疾病的组合物和方法 Pending CN106029078A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210078304.4A CN114452298A (zh) 2013-12-19 2014-12-19 使用基于藻酸的抗微生物化合物抑制炎症和疾病的组合物和方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361918445P 2013-12-19 2013-12-19
US61/918,445 2013-12-19
PCT/US2014/071664 WO2015095793A1 (en) 2013-12-19 2014-12-19 Compositions and methods for inhibiting inflammation and diseases using an alginic acid-based antimicrobial compound

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202210078304.4A Division CN114452298A (zh) 2013-12-19 2014-12-19 使用基于藻酸的抗微生物化合物抑制炎症和疾病的组合物和方法

Publications (1)

Publication Number Publication Date
CN106029078A true CN106029078A (zh) 2016-10-12

Family

ID=53403777

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201480075975.9A Pending CN106029078A (zh) 2013-12-19 2014-12-19 使用基于藻酸的抗微生物化合物抑制炎症和疾病的组合物和方法
CN202210078304.4A Pending CN114452298A (zh) 2013-12-19 2014-12-19 使用基于藻酸的抗微生物化合物抑制炎症和疾病的组合物和方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN202210078304.4A Pending CN114452298A (zh) 2013-12-19 2014-12-19 使用基于藻酸的抗微生物化合物抑制炎症和疾病的组合物和方法

Country Status (15)

Country Link
US (3) US11337989B2 (enExample)
EP (2) EP3082826B1 (enExample)
JP (3) JP2017501227A (enExample)
KR (1) KR102407408B1 (enExample)
CN (2) CN106029078A (enExample)
AU (2) AU2014368971B2 (enExample)
BR (1) BR112016014506B1 (enExample)
DK (1) DK3082826T3 (enExample)
ES (1) ES2790703T3 (enExample)
IL (1) IL246146B2 (enExample)
MX (2) MX2016008023A (enExample)
NZ (1) NZ722215A (enExample)
RU (1) RU2691950C1 (enExample)
WO (1) WO2015095793A1 (enExample)
ZA (1) ZA201604862B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013187984A1 (en) 2012-06-13 2013-12-19 Evofem, Inc. Compositions and methods for enhancing the efficacy of contraceptive microbicides
NZ722215A (en) 2013-12-19 2019-02-22 Evofem Inc Compositions and methods for inhibiting inflammation and diseases using an alginic acid-based antimicrobial compound
DE102017110168A1 (de) 2016-05-25 2017-11-30 Samsung Electronics Co., Ltd. Elektronische Vorrichtung mit NFC-Antenne
US20190209502A1 (en) * 2016-09-12 2019-07-11 Evofem, Inc. Combination gel for sexually transmitted infections
AU2017338748A1 (en) * 2016-10-04 2019-05-02 Evofem Inc. Method of treatment and prevention of bacterial vaginosis
WO2023076968A1 (en) * 2021-10-28 2023-05-04 Evofem, Inc. Rapidly dissolving vaginal film with contraceptive action and sexually transmitted infection prevention

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1431895A (zh) * 2000-03-07 2003-07-23 拉什-长老会-圣路加医学中心 捕获和灭活病原性微生物和精子的组合物和方法

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1213323B (it) 1986-08-07 1989-12-20 Crinos Industria Farmaco Composizione per uso locale ad atti vita' spermicida virulicida ,disinfettante e/o battericida
US4999342A (en) 1988-08-16 1991-03-12 Ortho Pharmaceutical Corporation Long lasting contraceptive suppository composition and methods of use
JP3202365B2 (ja) * 1992-12-04 2001-08-27 株式会社紀文フードケミファ オリゴマンヌロン酸を重合度によって分離する方法
US5592949A (en) 1994-06-29 1997-01-14 Moench; Thomas R. Device for acidic buffering and method for inactivation of pathogens
US5667492A (en) 1994-10-07 1997-09-16 Columbia Laboratories, Inc. Use and composition of an anti-sexually transmitted diseases formulation
FR2728464B1 (fr) 1994-12-22 1997-04-30 Innothera Lab Sa Forme galenique unitaire, son procede d'obtention et ses utilisations
US6093394A (en) 1997-04-11 2000-07-25 Gynelogix, Inc. Vaginal lactobacillus medicant
WO2001038284A1 (en) 1999-11-24 2001-05-31 Cargill Dow Llc Improved lactic acid processing; methods; arrangements; and, products
JP2009102407A (ja) * 2001-03-08 2009-05-14 Rohto Pharmaceut Co Ltd Ｇリッチなアルギン酸含有組成物
US20020177624A1 (en) 2001-03-16 2002-11-28 Calvin Hanna Acetate-lactate buffering vaginal gel and for method of making same and treating bacterial vaginosis
ITMI20010913A1 (it) 2001-05-04 2002-11-04 Univ Pavia Composizioni a rilascio controllato di acido lattico a livello vaginale
EP1399151A4 (en) * 2001-06-11 2004-08-04 Merck & Co Inc METHOD FOR TREATING INFLAMMABLE DISEASES BY ADMINISTRATING A PPAR DELTA AGONIST
US20130150810A1 (en) 2002-04-30 2013-06-13 The Population Council, Inc. Intravaginal ring for the delivery of unique combinations of antimicrobial compositions
WO2004011032A1 (ja) * 2002-07-26 2004-02-05 Mikasa Seiyaku Co., Ltd. 外用剤
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
DK1635847T3 (da) 2003-06-13 2019-10-28 Idh Holding Aps Behandling af symptomer forbundet med bakteriel vaginose
US20050272700A1 (en) 2004-05-10 2005-12-08 Servet Buyuktimkin Topical treatment and prevention of human papilloma virus (HPV) infection
RU2257197C1 (ru) * 2004-05-12 2005-07-27 Дулькис Мария Дмитриевна Вагинальные суппозитории, обладающие контрацептивным действием
UA93354C2 (ru) 2004-07-09 2011-02-10 Гилиад Сайенсиз, Инк. Местный противовирусный препарат
WO2008056786A1 (fr) * 2006-11-10 2008-05-15 Rohto Pharmaceutical Co., Ltd. Composition pour application cutanée ou par voie muqueuse
US7659259B2 (en) * 2006-12-21 2010-02-09 Bausch & Lomb Incorporated Method of treating inflammation of the eye
RU2459620C2 (ru) 2007-03-30 2012-08-27 Лаккуре Аб Применение олигомеров молочной кислоты в лечении гинекологических расстройств
EP2146698A2 (en) 2007-05-24 2010-01-27 New York Blood Center, Inc. Rapidly dispersible vaginal tablet that provides a bioadhesive gel
TW200927141A (en) 2007-11-22 2009-07-01 Bayer Schering Pharma Oy Vaginal delivery system
MX2010011244A (es) 2008-04-16 2010-11-09 Cipla Ltd Combinaciones topicas las cuales comprenden una agente antimicotico y un agente antiviral.
WO2009155118A1 (en) * 2008-05-30 2009-12-23 Reprotect, Inc. Compositions and methods for inactivation of pathogens at genital tract surfaces
EP2130531A1 (en) 2008-06-04 2009-12-09 Rolf Kullgren AB Vaginal suppository comprising lactic acid
WO2010142761A1 (en) 2009-06-10 2010-12-16 Ultimorphix Technologies B.V. The succinate of tenofovir disoproxil
MX2013012745A (es) * 2011-05-02 2014-12-05 Aptalis Pharmatech Inc Composiciones en forma de comprmido de disolución rápida para administración vaginal.
BR112013033759B1 (pt) 2011-06-28 2021-05-25 Chemo Research Sl forma de dosagem unitária de um gel de base aquosa de metronidazol mucoadesivo e uso relacionado ao gel de base aquosa de metronidazol
WO2013187984A1 (en) 2012-06-13 2013-12-19 Evofem, Inc. Compositions and methods for enhancing the efficacy of contraceptive microbicides
WO2015027071A1 (en) 2013-08-21 2015-02-26 Georgia Regents Research Institute, Inc. Gpr81 agonists and methods thereof for promoting production of secretory iga
NZ722215A (en) 2013-12-19 2019-02-22 Evofem Inc Compositions and methods for inhibiting inflammation and diseases using an alginic acid-based antimicrobial compound
US9801839B2 (en) 2014-02-28 2017-10-31 Macfarlane Burnet Institute For Medical Research And Public Health Pty Ltd Therapeutic method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1431895A (zh) * 2000-03-07 2003-07-23 拉什-长老会-圣路加医学中心 捕获和灭活病原性微生物和精子的组合物和方法

Also Published As

Publication number Publication date
IL246146B1 (en) 2023-11-01
MX2021001742A (es) 2021-04-19
RU2016129069A (ru) 2018-01-23
JP2022070924A (ja) 2022-05-13
KR102407408B1 (ko) 2022-06-10
EP3082826A4 (en) 2017-08-23
IL246146A0 (en) 2016-07-31
BR112016014506A2 (pt) 2017-10-31
US11337989B2 (en) 2022-05-24
CN114452298A (zh) 2022-05-10
JP2017501227A (ja) 2017-01-12
ZA201604862B (en) 2017-08-30
RU2691950C1 (ru) 2019-06-19
AU2020202835A1 (en) 2020-05-21
ES2790703T3 (es) 2020-10-28
IL246146B2 (en) 2024-03-01
DK3082826T3 (da) 2020-05-04
KR20160103036A (ko) 2016-08-31
JP2020125298A (ja) 2020-08-20
AU2014368971A1 (en) 2016-07-28
US20160354394A1 (en) 2016-12-08
EP3735966A1 (en) 2020-11-11
BR112016014506B1 (pt) 2022-06-28
US20240299426A1 (en) 2024-09-12
AU2014368971B2 (en) 2020-02-06
EP3082826A1 (en) 2016-10-26
AU2020202835B2 (en) 2021-12-02
WO2015095793A1 (en) 2015-06-25
EP3082826B1 (en) 2020-03-11
NZ722215A (en) 2019-02-22
MX2016008023A (es) 2017-01-13
US20220241301A1 (en) 2022-08-04

Similar Documents

Publication Publication Date Title
AU2020202835B2 (en) Compositions and methods for inhibiting inflammation and diseases using an alginic acid-based antimicrobial compound
US11992472B2 (en) Compositions and methods for enhancing the efficacy of contraceptive microbicides
HK40041070A (en) Compositions and methods for inhibiting inflammation and diseases using an alginic acid-based antimicrobial compound
HK1230485B (en) Compositions and methods for inhibiting inflammation and diseases using an alginic acid-based antimicrobial compound
HK1230485A1 (en) Compositions and methods for inhibiting inflammation and diseases using an alginic acid-based antimicrobial compound
HK40021110A (en) Compositions and methods for enhancing the efficacy of contraceptive microbicides
OA17704A (en) Compositions and methods for enhancing the efficacy of contraceptive microbicides.
EA041271B1 (ru) Противозачаточная микробицидная композиция и способ предупреждения заболеваний, передающихся половым путем

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20161012