CN106018786B - For detecting the intelligent detection equipment of Procalcitonin - Google Patents

For detecting the intelligent detection equipment of Procalcitonin Download PDF

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Publication number
CN106018786B
CN106018786B CN201610561542.5A CN201610561542A CN106018786B CN 106018786 B CN106018786 B CN 106018786B CN 201610561542 A CN201610561542 A CN 201610561542A CN 106018786 B CN106018786 B CN 106018786B
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China
Prior art keywords
reaction plate
channel
serum
procalcitonin
box body
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CN201610561542.5A
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CN106018786A (en
Inventor
陶少强
李玉峰
张士伟
张斌
王晓杨
杨彦齐
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Anhui National Science Biotechnology Co., Ltd.
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Anhui National Science Biotechnology Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302Apparatus specially adapted for immunological test procedures
    • G01N33/5304Reaction vessels, e.g. agglutination plates

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention discloses a kind of for detecting the intelligent detection equipment of Procalcitonin, including slide and reaction plate and box body, the reaction plate is located on slide, bottom surface and the upper surface of slide fit below reaction plate, reaction plate is rubber slab, the reaction plate is equipped with serum holding tank and one group of reactive tank, reaction plate one end is equipped with the serum being connected with serum holding tank and adds in channel, the entrance that serum adds in channel is located on the end face of reaction plate one end, serum holding tank is connected by channel with each reactive tank in the reaction plate, the reactive tank stagger setting of channel both sides, on the reaction plate waterleaf paper is equipped on the outside of each reactive tank, the channel is ramp way, channel is higher than by serum holding tank side by reactive tank side, Procalcitonin antibody is equipped in the reactive tank and is coated with locating slot;Reaction plate and slide are located in box body.The Procalcitonin antibody that can be used for a variety of concentration with a detection device detects it simultaneously respectively.

Description

For detecting the intelligent detection equipment of Procalcitonin
Technical field
The present invention relates to technical field of biological, are set more particularly, to a kind of for detecting the intelligent measurement of Procalcitonin It is standby.
Background technology
Procalcitonin is the calcitonin precursor substance of no hormonal activity.When serious bacterial, fungi, parasitic infection and purulence Its horizontal raising in blood when toxication and multiple organ failure.Procalcitonin when autoimmunity, allergy and virus infection It will not increase.It needs to be detected it respectively with the Procalcitonin antibody of various concentration during detection, ensures the accuracy of detection. Existing intelligent detection equipment single can only carry out, and the operating time is long, of high cost, and detection efficiency is low.
Invention content
In view of the shortcomings of the prior art, the technical problems to be solved by the invention be to provide it is a kind of for detecting Procalcitonin Intelligent detection equipment, to achieve the purpose that detection efficiency is high.
In order to solve the above-mentioned technical problem, the technical solution adopted in the present invention is:
This is used for the intelligent detection equipment for detecting Procalcitonin, including slide and reaction plate and box body, the reaction plate It is located on slide, reaction plate is located at the surface of slide, and bottom surface and the upper surface of slide fit below reaction plate, and reaction plate is Rubber slab, the reaction plate are equipped with serum holding tank and one group of reactive tank, and reaction plate one end is equipped with to be connected with serum holding tank Logical serum adds in channel, and the entrance that serum adds in channel is located on the end face of reaction plate one end, and serum is deposited in the reaction plate Storage tank is connected by channel with each reactive tank, the reactive tank stagger setting of channel both sides, each anti-on the reaction plate It answers and waterleaf paper is equipped on the outside of slot, the channel is ramp way, and channel is higher than by serum holding tank side by reactive tank side, institute It states and Procalcitonin antibody coating locating slot is equipped in reactive tank;It is opening above the box body, opening is equipped with protrusion inwardly Snap-gauge, reaction plate and slide are located between the bottom plate of box body and snap-gauge, and box body is transparent box body.
Further, Procalcitonin antibody coating locating slot is the annular groove being located in reactive tank, the slot of annular groove Wall is equipped with one group of through-hole.
Channel on the reaction plate includes main channel and subchannel, and main channel one end is connected with serum holding tank, main logical The road other end is equipped with main channel end waterleaf paper, and each reactive tank is connected by subchannel with main channel.
The upper surface edge of the slide is equipped with raised item, and the bottom surface edge of reaction plate is equipped with corresponding fixed with raised item Position groove.
Cover board is further included, the snap-gauge is equipped with card slot, and deck side edge can be inserted into card slot.
The bottom plate of the box body is equipped with opening.
The upper surface edge of the reaction plate is equipped with positioning convex strip, and the snap-gauge is equipped with and the corresponding rail of positioning convex strip Slot.
The positioning groove is dovetail groove.
The cover board be L-square, L-square include transverse slat and riser, transverse slat is corresponding with box body upper opening, riser and The opening of box body side is corresponding, and riser is equipped with the opening that channel is added in serum.
Compared with prior art, the present invention it has the following advantages:This is used for the intelligent detection equipment knot for detecting Procalcitonin Structure reasonable design, the Procalcitonin antibody that can be used for a variety of concentration with a detection device detect it simultaneously respectively, without Repeated detection is carried out, detection efficiency is high, reduces testing cost.
Description of the drawings
The content to this specification expressed by each width attached drawing and the label in figure are briefly described below:
Fig. 1 is present invention reaction plate structure schematic diagram.
Fig. 2 is the left view of Fig. 1.
Fig. 3 is slide structure diagram of the present invention.
Fig. 4 is box body structure schematic diagram of the present invention.
Fig. 5 is covering plate structure schematic diagram of the present invention.
In figure:
1. reaction plate, 2. positioning convex strips, 3. serum holding tanks, 4. main channels, 5. main channel end waterleaf papers, 6. reactions Slot, 7. Procalcitonin antibody coating locating slot, 8. subchannel waterleaf papers, 9. subchannels, 10. serum add in channel, 11. slides, 12. raised item, 13. convex blocks, 14. box bodys, 15. snap-gauges, 16. track slots, 17. card slots, 18. cover boards.
Specific embodiment
Below against attached drawing, by the description of the embodiment, making to the specific embodiment of the present invention further details of Explanation.
As shown in Figures 1 to 5, intelligent detection equipment for being used to detect Procalcitonin, including slide 11, reaction plate 1, box Body 14 and cover board 18, wherein, reaction plate is located on slide, and reaction plate 1 is located at the surface of slide, and slide is the branch of reaction plate Carrier is supportted, reaction plate is rectangle tabular structure as the size dimension of slide.
1 lower section bottom surface of reaction plate and the upper surface of slide 11 fit, and the upper surface edge of slide 11 is equipped with raised item 12, The bottom surface edge of reaction plate be equipped with 12 corresponding positioning groove of raised item, positioning groove is dovetail groove, ensure slide 11 on Surface is bonded effect with 1 bottom surface of reaction plate;Be equipped with convex block on the inside of raised item one end of slide, positioning groove one end be equipped with it is convex The corresponding slot of block, positions reaction plate and slide.Reaction plate is rubber slab, rubber slab and slide flexible contact, and fitting is imitated Fruit is good.
Reaction plate 1 is equipped with serum holding tank 3 and one group of reactive tank 6, and 1 one end of reaction plate is equipped with to be connected with serum holding tank Logical serum adds in channel 10, and the entrance that serum adds in channel 10 is located on the end face of 1 one end of reaction plate, and serum adds in channel Entrance can be connected with syringe, be added in convenient for serum.
Serum holding tank 3 is connected by channel with each reactive tank 6 in reaction plate 1, in each reactive tank on reaction plate 1 Outside be equipped with waterleaf paper, channel is ramp way, and channel is higher than by serum holding tank side by reactive tank side, in reactive tank 6 Locating slot 7 is coated with equipped with Procalcitonin antibody.
Channel includes main channel 4 and subchannel 9, and 4 one end of main channel is connected with serum holding tank 3, and 4 other end of main channel is set There is main channel end waterleaf paper 5, each reactive tank is connected by subchannel with main channel.In the outer of each reactive tank on reaction plate Side is equipped with subchannel waterleaf paper 8.
The serum added in serum holding tank 3 can be drawn onto automatically in reactive tank 6 by waterleaf paper, each Procalcitonin resists Procalcitonin antibody concentration in body coating locating slot 7 is different, is coated with as nitrocellulose filter, nitrocellulose filter is calcitonin Original antibody stationary support, the Procalcitonin antibody that can be used for a variety of concentration with a detection device examine it simultaneously respectively It surveys, without carrying out repeated detection, detection efficiency is high, and testing cost is low.
Procalcitonin antibody coating locating slot 7 is the annular groove being located in reactive tank, and the cell wall of annular groove is equipped with one group Outside communicates in through-hole, i.e. cell wall.The both sides of main channel 4 are equipped with subchannel 9, and the subchannel of main channel both sides shifts to install, 6 stagger setting of reactive tank of i.e. main logical 4 both sides, it is ensured that the reliability of detection.
Box body 14 is fixed the two for accommodating reaction plate 1 and slide 11.Box body is rectangular box-like structure, box Above body and one side is opening, and 1 upper opening of box body is equipped with the snap-gauge 15 of protrusion inwardly, and reaction plate 1 and slide 11 are located at Between the bottom plate of box body 14 and snap-gauge 15.It can be inserted into box body by the opening of box body side after reaction plate and slide cooperation.
The upper surface edge of reaction plate 1 is equipped with positioning convex strip 2, and snap-gauge 1 is equipped with and 2 corresponding track slot of positioning convex strip 16, reaction plate and slide are inserted into box body 14, ensure position of the two in box body by positioning convex strip, fixing-stable can It leans on.
Snap-gauge 15 is equipped with card slot 17, and 18 side of cover board can be inserted into card slot 17.Cover board 18 is L-square, and L-square includes Transverse slat and riser, transverse slat is corresponding with the opening on box body top, and riser is corresponding with the opening of box body side.Riser be equipped with Serum adds in the opening of channel, convenient for adding in serum.Cover board 18 is hollow plastic plate, and cover board 18 is squeezed elastically deformable, Cover board, which is inserted into card slot, to be positioned reliably, and cover board 18 is transparent panel.
The bottom plate of box body 14 is equipped with opening or box body 14 is transparent box body, it is ensured that detection result;Such as box body Bottom plate is equipped with opening, and opening can be rectangular opening, pass through support of the edge of opening to slide.
The present invention is exemplarily described above in conjunction with attached drawing, it is clear that present invention specific implementation is not by aforesaid way Limitation, as long as employ the present invention design and technical solution carry out various unsubstantialities improvement or it is not improved will The design and technical solution of the present invention directly applies to other occasions, within protection scope of the present invention.

Claims (7)

1. a kind of intelligent detection equipment for being used to detect Procalcitonin, it is characterised in that:Including slide and reaction plate and box body, The reaction plate is located on slide, and reaction plate is located at the surface of slide, and bottom surface and the upper surface of slide are affixed below reaction plate It closes, reaction plate is rubber slab, and the reaction plate is equipped with serum holding tank and one group of reactive tank, and reaction plate one end is equipped with and serum The serum that holding tank is connected adds in channel, and the entrance that serum adds in channel is located on the end face of reaction plate one end, the reaction Serum holding tank is connected by channel with each reactive tank in plate, the reactive tank stagger setting of channel both sides, the reaction plate On be equipped with waterleaf paper on the outside of each reactive tank, the channel is ramp way, and channel is by serum holding tank side higher than leaning on Reactive tank side, the interior Procalcitonin antibody that is equipped with of the reactive tank are coated with locating slot;It is opening above the box body, opening is inwardly Snap-gauge equipped with protrusion, reaction plate and slide are located between the bottom plate of box body and snap-gauge, and box body is transparent box body;The drop calcium Plain original antibody coating locating slot is the annular groove being located in reactive tank, and the cell wall of annular groove is equipped with one group of through-hole;The reaction Channel on plate includes main channel and subchannel, and main channel one end is connected with serum holding tank, and the main channel other end is equipped with main logical Road end waterleaf paper, each reactive tank are connected by subchannel with main channel.
2. it is used to detect the intelligent detection equipment of Procalcitonin as described in claim 1, it is characterised in that:The upper table of the slide Face edge is equipped with raised item, and the bottom surface edge of reaction plate is equipped with and the corresponding positioning groove of raised item.
3. it is used to detect the intelligent detection equipment of Procalcitonin as described in claim 1, it is characterised in that:Cover board is further included, institute Snap-gauge is stated equipped with card slot, deck side edge can be inserted into card slot.
4. it is used to detect the intelligent detection equipment of Procalcitonin as described in claim 1, it is characterised in that:The bottom plate of the box body It is equipped with opening.
5. it is used to detect the intelligent detection equipment of Procalcitonin as described in claim 1, it is characterised in that:The reaction plate it is upper Surface edge is equipped with positioning convex strip, and the snap-gauge is equipped with and the corresponding track slot of positioning convex strip.
6. it is used to detect the intelligent detection equipment of Procalcitonin as claimed in claim 2, it is characterised in that:The positioning groove is Dovetail groove.
7. it is used to detect the intelligent detection equipment of Procalcitonin as claimed in claim 3, it is characterised in that:The cover board is right angle Plate, L-square include transverse slat and riser, and transverse slat is corresponding with box body upper opening, and riser is corresponding with the opening of box body side, Riser is equipped with the opening that channel is added in serum.
CN201610561542.5A 2016-07-15 2016-07-15 For detecting the intelligent detection equipment of Procalcitonin Active CN106018786B (en)

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CN106018786B true CN106018786B (en) 2018-06-29

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2565022Y (en) * 2002-08-23 2003-08-06 上海博昇微晶科技有限公司 Microfluid chip with three-layer structure
CN101382538A (en) * 2007-09-04 2009-03-11 财团法人工业技术研究院 Auto-shunting microfluid apparatus
CN103389303A (en) * 2013-08-07 2013-11-13 苏州扬清芯片科技有限公司 Multi-index analysis paper chip and preparation method thereof
CN104226385A (en) * 2013-06-09 2014-12-24 北京百康芯生物科技有限公司 A novel micro-fluidic chip and a using method thereof
CN205879952U (en) * 2016-07-15 2017-01-11 陶少强 A intelligent detection equipment for detecting calcitonin is former

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6090330B2 (en) * 2012-10-31 2017-03-08 日立化成株式会社 Sensor chip and measurement system

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2565022Y (en) * 2002-08-23 2003-08-06 上海博昇微晶科技有限公司 Microfluid chip with three-layer structure
CN101382538A (en) * 2007-09-04 2009-03-11 财团法人工业技术研究院 Auto-shunting microfluid apparatus
CN104226385A (en) * 2013-06-09 2014-12-24 北京百康芯生物科技有限公司 A novel micro-fluidic chip and a using method thereof
CN103389303A (en) * 2013-08-07 2013-11-13 苏州扬清芯片科技有限公司 Multi-index analysis paper chip and preparation method thereof
CN205879952U (en) * 2016-07-15 2017-01-11 陶少强 A intelligent detection equipment for detecting calcitonin is former

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Address after: 241000 Anhui Province, Wuhu city Jinghu District long Fang Culture Park (big long Fang No. 77) B03 Building Room 303

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