CN106000148B - Automatic cycle liquid feeding system - Google Patents
Automatic cycle liquid feeding system Download PDFInfo
- Publication number
- CN106000148B CN106000148B CN201610536606.6A CN201610536606A CN106000148B CN 106000148 B CN106000148 B CN 106000148B CN 201610536606 A CN201610536606 A CN 201610536606A CN 106000148 B CN106000148 B CN 106000148B
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- China
- Prior art keywords
- liquid
- wet tank
- valve
- consumed
- branch
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/50—Circulation mixers, e.g. wherein at least part of the mixture is discharged from and reintroduced into a receptacle
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/01—Separation of suspended solid particles from liquids by sedimentation using flocculating agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/21—Measuring
- B01F35/211—Measuring of the operational parameters
- B01F35/2111—Flow rate
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/21—Measuring
- B01F35/211—Measuring of the operational parameters
- B01F35/2113—Pressure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/21—Measuring
- B01F35/211—Measuring of the operational parameters
- B01F35/2115—Temperature
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/80—Forming a predetermined ratio of the substances to be mixed
- B01F35/88—Forming a predetermined ratio of the substances to be mixed by feeding the materials batchwise
- B01F35/883—Forming a predetermined ratio of the substances to be mixed by feeding the materials batchwise using flow rate controls for feeding the substances
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/90—Heating or cooling systems
- B01F35/92—Heating or cooling systems for heating the outside of the receptacle, e.g. heated jackets or burners
Abstract
Automatic cycle liquid feeding system disclosed by the invention, including wet tank, heat exchanger, circulating pump, liquid-consumed branch and controller, the liquid outlet of the inlet connection wet tank of circulating pump, the import of the liquid outlet connection heat exchanger of circulating pump, the outlet of heat exchanger connects the circulating liquid entrance of wet tank by pipeline, wet tank is provided with temperature sensor A, liquid level sensor and liquid-level switch, liquid-consumed branch is connected in the connecting pipe between the outlet of heat exchanger and the circulating liquid entrance of wet tank, temperature sensor B is set in the connecting pipe between the outlet of heat exchanger and liquid-consumed branch, temperature sensor C is provided in connecting pipe between liquid-consumed branch and the circulating liquid entrance of wet tank, pressure sensor and pressure-regulating valve.High degree of automation of the present invention, can Improving The Quality of Products, raising efficiency.
Description
Technical field
The present invention relates to a kind of pharmaceutical production equipment more particularly to a kind of automatic cycle liquid feeding systems.
Background technique
In pharmaceutical production, existing mode needs to prepare in advance, adds by storage tank, and operator monitors that tank level becomes
Change or other manual types adjust liquid acceleration etc., cumbersome, low efficiency.
Summary of the invention
The present invention is intended to provide a kind of automatic cycle liquid feeding system, high degree of automation can Improving The Quality of Products, promotion effect
Rate.
In order to achieve the above objectives, realization that the present invention adopts the following technical solutions:
Automatic cycle liquid feeding system disclosed by the invention, including wet tank, heat exchanger, circulating pump, liquid-consumed branch
And controller, the circulating pump inlet connection wet tank liquid outlet, circulating pump liquid outlet connection heat exchanger into
Mouthful, the outlet of the heat exchanger connects the circulating liquid entrance of wet tank by pipeline, and the wet tank is provided with temperature
Sensors A, liquid level sensor and liquid-level switch, the liquid-consumed branch are connected to the outlet of heat exchanger and following for wet tank
In connecting pipe between ring liquid inlet, liquid-consumed branch road setting mass flowmenter, flow control valve and automatic switch
Valve B, heat exchanger export and setting temperature sensor B, heat exchanger refrigerant feed liquor in the connecting pipe between liquid-consumed branch
Temperature control valve (TCV) is set on pipeline, automatic switch valve A, the circulation fluid of liquid-consumed branch and wet tank are set on back liquid pipeline
Temperature sensor C, pressure sensor and pressure-regulating valve, the temperature sensor are provided in connecting pipe between body entrance
A, temperature sensor B, temperature sensor C, pressure sensor, mass flowmenter, flow control valve, temperature control valve (TCV), pressure tune
Section valve, liquid level sensor, liquid-level switch, circulating pump are electrically connected with the controller.
Preferably, the controller includes central processing unit, filtering/amplifying circuit, A/D conversion circuit, D/A conversion electricity
Road, display screen, key；The temperature sensor A, temperature sensor B, temperature sensor C, pressure sensor, liquid level sensor,
Mass flowmenter is all connected with filtering/amplifying circuit, and the filtering/amplifying circuit connects A/D conversion circuit, the A/D conversion electricity
Road connects central processing unit, and the central processing unit connection D/A conversion circuit, circulating pump, automatic switch valve, liquid level are opened
It closes, the D/A conversion circuit connection flow control valve, temperature control valve (TCV) and pressure-regulating valve, the display screen, key are all connected with
Central processing unit.
Further, the wet tank is provided with filling opening, and the filling opening, circulating liquid entrance are respectively positioned on liquid storage
Tank top, the liquid outlet are located at the bottom of wet tank.
Further, the end of the liquid-consumed branch connects alcohol nozzle.
Preferably, the liquid-consumed branch has 12.
Further, the wet tank top is equipped with overflow port.
Further, fire-retardant breather valve is equipped at the top of the wet tank.
Further, the liquid outlet of the wet tank, the refrigerant inlet of heat exchanger, the inlet of liquid-consumed branch are equal
It is provided with hand valve.
Further, the circulating pump is provided with exhaust-valve, and the exhaust-valve is hand valve.
In the use of the present invention, operating parameter, start-up and shut-down control, operation data inquiry and process can be arranged by operation interface
Message notifying, including circulation and liquid feeding.Specifically, can include: circulating start and outage, temperature, pressure, wet tank Liquid level add
The start and stop of liquid point, liquid feeding total amount, each stage flow velocity and each stage receiving tank products temperature control, the liquid feeding time, Daily temperature range,
The operation datas such as liquid volume added are counted and are inquired.
Beneficial effects of the present invention are as follows:
1, liquid feeding process simplification: the present invention can realize determining for liquid by the terminal flowmeter and regulating valve of each liquid feeding point
Amount, constant speed are added automatically, simple and quick.It avoids traditional approach to need to prepare in advance, be added by storage tank, operator
Monitor tank level variation or the troublesome operation that other manual types adjustment liquid accelerates.
2, occupy equipment to reduce: a wet tank, heat exchanger, circulating pump and addition point terminal flow is used only in this system
Meter and regulating valve are not take up other storage containers, reduce process operation and cleaning, accordingly reducing the ejected wash waters such as water for injection makes
Dosage.
3, can guarantee fluid temperature: the present invention can make fluid temperature control be guaranteed using heat exchanger according to demand, by
In liquid from major cycle pipeline to each liquid feeding point apart from short and have Insulation, so that fluid temperature variation is small, it is ensured that liquid
Temperature meets manufacturing technique requirent.
4, high degree of automation: this system is automatically controlled by computer program, and user can require control according to process requirements
The emergency disposal program that computer system automatically controls, when including occurring abnormal is realized in write-in program, such as wet tank low liquid level
Protective program, fluid temperature hypervisor limit protective program, protective program when unit exception, protection journey when liquid feeding volume exception
Sequence etc., utmostly improves security of system.The system control program can be with various processes in liquid adding procedure
The control of product requires cooperation, as the product temperature control during liquid feeding can be automatically controlled according to demand by program.Liquid feeding is automatic
The realization for changing control, reduces labor intensity while improving the safety of liquid feeding process.
5, product quality and yield are promoted: the automation control of liquid feeding improves the fine degree of production technology, reduces
The stable different batches of product of quality can be obtained in the differences between batches of product.
Specific to the production of blood product, significant advantage is during Protein Separation, and ethyl alcohol adds uniform, controllable,
Reduce the heat of solution that ethyl alcohol adding procedure is discharged, ethyl alcohol mixes more uniform with product, makes albumin Quality advance, white egg
Bai Chundu is increased, and polymer reduces.Since precipitating forms more excellent in ethyl alcohol adding procedure, the globulin rate of recovery is mentioned
It rises.Albumin and the differences between batches of the globulin rate of recovery reduce and tend towards stability.
Detailed description of the invention
Fig. 1 is schematic structural view of the invention；
Fig. 2 is the functional block diagram of controller；
In figure: 1- wet tank, 2- circulating pump, 3- heat exchanger, 4- refrigerant exit, 5- automatic switch valve A, 6- refrigerant into
Mouth, 7- hand valve B, 8- temperature control valve (TCV), 9- pressure sensor, 10- temperature sensor C, 11- hand valve C, 12- mass flowmenter,
13- flow control valve, 14- automatic switch valve B, 15- alcohol nozzle, 16- filling opening, 17- circulating liquid entrance, 18- overflow port,
19- liquid-level switch, 20- liquid level sensor, 21- hand valve A, 22- temperature sensor A, 23- exhaust-valve, 24- pressure-regulating valve, 25-
Temperature sensor B, 26- fire-retardant breather valve.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, below in conjunction with attached drawing, to the present invention into
Row is further described.
As shown in Figure 1, automatic cycle liquid feeding system disclosed by the invention, including wet tank 1, heat exchanger 3, circulating pump 2,
Liquid-consumed branch and controller, the liquid outlet of the inlet connection wet tank of circulating pump 2, the liquid outlet connection of circulating pump are changed
The import of hot device 3, the outlet of heat exchanger connect the circulating liquid entrance 17 of wet tank 1 by pipeline, and wet tank 1 is provided with
Temperature sensor A22, liquid level sensor 20,1 top of wet tank are equipped with liquid-level switch 19, overflow port 18；Liquid-consumed branch
It is connected in the connecting pipe between the outlet of heat exchanger 3 and the circulating liquid entrance 17 of wet tank 1, the outlet of heat exchanger 3
Temperature sensor B25, the circulation of liquid-consumed branch and wet tank 1 are set in the connecting pipe between liquid-consumed branch
Temperature sensor C10, pressure sensor 9 and pressure-regulating valve 24, temperature are provided in connecting pipe between liquid inlet 17
Sensors A 22, temperature sensor B25, temperature sensor C10, pressure sensor 9, pressure-regulating valve 24, liquid level sensor 20,
Liquid-level switch 19, circulating pump 2 are electrically connected with the controller；Filling opening 16, filling opening 16, circulation are provided at the top of wet tank 1
Liquid inlet 17, fire-retardant breather valve 26, liquid outlet are located at the bottom of wet tank 1；It is provided in the refrigerant inlet 6 of heat exchanger 3
Temperature control valve (TCV) 8 is provided with automatic switch valve A5 on 3 refrigerant exits 4 of heat exchanger；Liquid-consumed branch includes being sequentially communicated
Mass flowmenter 12, flow control valve 13, automatic switch valve B14 and alcohol nozzle 15, liquid-consumed branch can have multiple, tool
Body is 12；Circulating pump 2 is provided with exhaust-valve 23, and exhaust-valve 23 uses hand valve；The liquid outlet of wet tank 1, heat exchanger 3
Refrigerant inlet, liquid-consumed branch inlet be respectively arranged with hand valve A21, hand valve B7, hand valve C11.Temperature control valve (TCV) 8, matter
Amount flowmeter 12, flow control valve 13 are electrically connected with the controller.
As shown in Fig. 2, controller includes central processing unit, filtering/amplifying circuit, A/D conversion circuit, D/A conversion electricity
Road, display screen, key；Temperature sensor A, temperature sensor B, temperature sensor C, pressure sensor, liquid level sensor, quality
Flowmeter is all connected with filtering/amplifying circuit, and filtering/amplifying circuit connects A/D conversion circuit, in the A/D conversion circuit connection
Central Processing Unit, central processing unit connect D/A conversion circuit, circulating pump, automatic switch valve, liquid-level switch, D/A conversion circuit
Connection flow control valve, temperature control valve (TCV) and pressure-regulating valve, display screen, key are all connected with central processing unit.
Certainly, the present invention can also have other various embodiments, without deviating from the spirit and substance of the present invention, ripe
Various corresponding changes and modifications, but these corresponding changes and modifications can be made according to the present invention by knowing those skilled in the art
All it should fall within the scope of protection of the appended claims of the present invention.
Claims (9)
1. automatic cycle liquid feeding system, it is characterised in that: including wet tank, heat exchanger, circulating pump, liquid-consumed branch and control
Device processed, the liquid outlet of the inlet connection wet tank of the circulating pump, the import of the liquid outlet connection heat exchanger of circulating pump, institute
The outlet for stating heat exchanger connects the circulating liquid entrance of wet tank by pipeline, and the wet tank is provided with temperature sensor
A, liquid level sensor and liquid-level switch, the liquid-consumed branch are connected to the outlet of heat exchanger and the circulating liquid of wet tank
In connecting pipe between entrance, liquid-consumed branch road setting mass flowmenter, flow control valve and automatic switch valve B are changed
Temperature sensor B is set in the connecting pipe between the outlet of hot device and liquid-consumed branch, in heat exchanger refrigerant input duct
Automatic switch valve A, the circulating liquid entrance of liquid-consumed branch and wet tank are set on setting temperature control valve (TCV), back liquid pipeline
Between connecting pipe on be provided with temperature sensor C, pressure sensor and pressure-regulating valve, the temperature sensor A, temperature
Sensor B, temperature sensor C, pressure sensor, mass flowmenter, flow control valve, temperature control valve (TCV), pressure-regulating valve, liquid
Level sensor, liquid-level switch, circulating pump are electrically connected with the controller.
2. automatic cycle liquid feeding system according to claim 1, it is characterised in that: the controller includes central processing list
Member, filtering/amplifying circuit, A/D conversion circuit, D/A conversion circuit, display screen, key；The temperature sensor A, temperature sensing
Device B, temperature sensor C, pressure sensor, liquid level sensor, mass flowmenter are all connected with filtering/amplifying circuit, and the filtering/
Amplifying circuit connects A/D conversion circuit, and the A/D conversion circuit connects central processing unit, the central processing unit connection
D/A conversion circuit, circulating pump, automatic switch valve, liquid-level switch, the D/A conversion circuit connection flow control valve, temperature are adjusted
Valve and pressure-regulating valve, the display screen, key are all connected with central processing unit.
3. automatic cycle liquid feeding system according to claim 1, it is characterised in that: the wet tank is provided with liquid feeding
Mouthful, the filling opening, circulating liquid entrance are respectively positioned at the top of wet tank, and the liquid outlet is located at the bottom of wet tank.
4. automatic cycle liquid feeding system according to claim 1, it is characterised in that: the end of the liquid-consumed branch connects
Connect alcohol nozzle.
5. automatic cycle liquid feeding system according to claim 1, it is characterised in that: the liquid-consumed branch has 12.
6. automatic cycle liquid feeding system according to claim 1, it is characterised in that: the wet tank top is equipped with overflow
Mouthful.
7. automatic cycle liquid feeding system according to claim 1, it is characterised in that: be equipped with back-fire relief at the top of the wet tank
Breather valve.
8. automatic cycle liquid feeding system according to claim 1, it is characterised in that: the liquid outlet of the wet tank changes
The refrigerant inlet of hot device, liquid-consumed branch inlet be provided with hand valve.
9. automatic cycle liquid feeding system according to claim 1, it is characterised in that: the circulating pump is provided with exhaust-valve,
The exhaust-valve is hand valve.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610536606.6A CN106000148B (en) | 2016-07-08 | 2016-07-08 | Automatic cycle liquid feeding system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610536606.6A CN106000148B (en) | 2016-07-08 | 2016-07-08 | Automatic cycle liquid feeding system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106000148A CN106000148A (en) | 2016-10-12 |
| CN106000148B true CN106000148B (en) | 2019-01-18 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610536606.6A Active CN106000148B (en) | 2016-07-08 | 2016-07-08 | Automatic cycle liquid feeding system |
Country Status (1)
| Country | Link |
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| CN (1) | CN106000148B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107056882B (en) * | 2017-03-15 | 2023-06-06 | 上海朗脉洁净技术股份有限公司 | Full-automatic ethanol adding system for blood product production |
| CN107678320B (en) * | 2017-11-27 | 2023-10-24 | 广东路得斯环境科技有限公司 | Full-automatic proportioning machine controller for cleaning agent of printing equipment |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0113831B1 (en) * | 2000-09-22 | 2010-11-30 | method for treating a body of liquid in a tank, method for operating a processing facility, and, processing facility. | |
| US9533270B2 (en) * | 2013-06-10 | 2017-01-03 | Robert James Law | Passive injection of a chemical solution into a process stream |
| CN204237657U (en) * | 2014-11-18 | 2015-04-01 | 华瑞制药有限公司 | For the aseptic preparation facilities without chlorine water coolant of food, medicine |
| CN205797001U (en) * | 2016-07-08 | 2016-12-14 | 成都蓉生药业有限责任公司 | Automatic Cycle liquid feeding system |
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2016
- 2016-07-08 CN CN201610536606.6A patent/CN106000148B/en active Active
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| Publication number | Publication date |
|---|---|
| CN106000148A (en) | 2016-10-12 |
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