CN106000148A - Automatic cycling liquid adding system - Google Patents
Automatic cycling liquid adding system Download PDFInfo
- Publication number
- CN106000148A CN106000148A CN201610536606.6A CN201610536606A CN106000148A CN 106000148 A CN106000148 A CN 106000148A CN 201610536606 A CN201610536606 A CN 201610536606A CN 106000148 A CN106000148 A CN 106000148A
- Authority
- CN
- China
- Prior art keywords
- liquid
- valve
- temperature sensor
- heat exchanger
- outlet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/50—Circulation mixers, e.g. wherein at least part of the mixture is discharged from and reintroduced into a receptacle
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D21/00—Separation of suspended solid particles from liquids by sedimentation
- B01D21/01—Separation of suspended solid particles from liquids by sedimentation using flocculating agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/21—Measuring
- B01F35/211—Measuring of the operational parameters
- B01F35/2111—Flow rate
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/21—Measuring
- B01F35/211—Measuring of the operational parameters
- B01F35/2113—Pressure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/21—Measuring
- B01F35/211—Measuring of the operational parameters
- B01F35/2115—Temperature
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/80—Forming a predetermined ratio of the substances to be mixed
- B01F35/88—Forming a predetermined ratio of the substances to be mixed by feeding the materials batchwise
- B01F35/883—Forming a predetermined ratio of the substances to be mixed by feeding the materials batchwise using flow rate controls for feeding the substances
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/90—Heating or cooling systems
- B01F35/92—Heating or cooling systems for heating the outside of the receptacle, e.g. heated jackets or burners
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- Filling Or Discharging Of Gas Storage Vessels (AREA)
Abstract
The invention discloses an automatic cycling liquid adding system. The automatic cycling liquid adding system comprises a liquid storage tank, a heat exchanger, a circulating pump, a liquid consuming branch and a controller. The liquid inlet of the circulating pump communicates with the liquid outlet of the liquid storage tank, the liquid outlet of the circulating pump communicates with the inlet of the heat exchanger, and the outlet of the heat exchanger is connected with the circulating liquid inlet of the liquid storage tank through a pipeline. The liquid storage tank is provided with a temperature sensor A, a liquid level sensor and a liquid level switch. The liquid consuming branch is connected to the connection pipeline between the outlet of the heat exchanger and the circulating liquid inlet of the liquid storage tank. A temperature sensor B is arranged on a connection pipeline between the outlet of the heat exchanger and the liquid consuming branch. A temperature sensor C, a pressure sensor and a pressure adjusting valve are arranged on a connection pipeline between the liquid consuming branch and the circulating liquid inlet of the liquid storage tank. The automatic cycling liquid adding system is high in automation degree, and the product quality and the efficiency can be improved.
Description
Technical field
The present invention relates to a kind of pharmaceutical production equipment, particularly relate to a kind of Automatic Cycle liquid feeding system.
Background technology
In pharmaceutical production, existing mode needs to prepare in advance, adds through storage tank, and operator monitor
Tank level change or other manual types adjust liquid acceleration etc., and complex operation, efficiency is low.
Summary of the invention
It is desirable to provide a kind of Automatic Cycle liquid feeding system, automaticity is high, can improving product matter
Amount, raising efficiency.
For reaching above-mentioned purpose, the present invention realizes by the following technical solutions:
Automatic Cycle liquid feeding system disclosed by the invention, including wet tank, heat exchanger, circulating pump, liquid
Body depletion arm and controller, the liquid outlet of the inlet connection wet tank of described circulating pump, circulating pump
The import of liquid outlet connection heat exchanger, the outlet of described heat exchanger connects the following of wet tank by pipeline
Ring liquid inlet, described wet tank is provided with temperature sensor A, liquid level sensor and liquid-level switch,
Described liquid-consumed branch road is connected to the company between the outlet of heat exchanger and the circulating liquid entrance of wet tank
On adapter road, liquid-consumed branch road arranges mass flowmenter, flow control valve and automatic switch valve B,
On connection pipeline between outlet and the liquid-consumed branch road of heat exchanger, temperature sensor B, heat exchanger are set
Arrange in coolant input duct and automatic switch valve A is set on temperature control valve (TCV), back liquid pipeline, liquid-consumed
It is provided with temperature sensor C, pressure on connection pipeline between the circulating liquid entrance of branch road and wet tank
Force transducer and pressure-regulating valve, described temperature sensor A, temperature sensor B, temperature sensor C,
Pressure transducer, mass flowmenter, flow control valve, temperature control valve (TCV), pressure-regulating valve, liquid level pass
Sensor, liquid-level switch, circulating pump are all electrically connected with the controller.
Preferably, described controller include CPU, filtering/amplifying circuit, A/D change-over circuit,
D/A change-over circuit, display screen, button；Described temperature sensor A, temperature sensor B, temperature sensing
Device C, pressure transducer, liquid level sensor, mass flowmenter are all connected with filtering/amplifying circuit, described filter
Ripple/amplifying circuit connects A/D change-over circuit, and described A/D change-over circuit connects CPU, described
CPU connects D/A change-over circuit, circulating pump, automatic switch valve, liquid-level switch, described D/A
Change-over circuit connection traffic regulation valve, temperature control valve (TCV) and pressure-regulating valve, described display screen, button are equal
Connect CPU.
Further, described wet tank is provided with filling opening, and described filling opening, circulating liquid entrance are equal
Being positioned at wet tank top, described liquid outlet is positioned at the bottom of wet tank.
Further, the end of described liquid-consumed branch road connects ethanol nozzle.
Preferably, described liquid-consumed branch road has 12.
Further, described wet tank top is provided with overfall.
Further, described wet tank top is provided with fire-retardant breather valve.
Further, the liquid outlet of described wet tank, the coolant import of heat exchanger, liquid-consumed branch road
Porch be provided with hands valve.
Further, described circulating pump is provided with exhaust-valve, and described exhaust-valve is hands valve.
The present invention in use, can arrange operational factor, on off control, service data by operation interface
Inquiry and procedure message are pointed out, including circulation and liquid feeding.Concrete, it may include: circulating start and outage, temperature,
Pressure, wet tank Liquid level, liquid feeding point start and stop, liquid feeding total amount, each stage flow velocity and each stage connect
Closed cans products temperature controls, and the service data such as liquid feeding time, Daily temperature range, liquid volume added is added up
And inquiry.
Beneficial effects of the present invention is as follows:
1, liquid feeding process simplification: the present invention can realize liquid by the terminal effusion meter of each liquid feeding point and regulation valve
Quantitative, the constant speed of body are added automatically, simple and quick.Avoid traditional approach to need to prepare in advance,
Adding through storage tank, operator monitor that tank level change or other manual types adjust what liquid accelerated
Troublesome operation.
2, the equipment that takies reduces: native system only uses a wet tank, heat exchanger, circulating pump and interpolation
Point terminal effusion meter and regulation valve, be not take up other storage containers, reduces process operation and cleaning, accordingly
Decrease the rinse water usage amounts such as water for injection.
3, temperature of liquid can be ensured: the present invention can use heat exchanger to make temperature of liquid control according to demand
To ensureing, due to liquid from major cycle pipeline to each liquid feeding point apart from short and have Insulation so that liquid
Variations in temperature is little, it is ensured that temperature of liquid meets manufacturing technique requirent.
4, automaticity is high: native system is automatically controlled by computer program, and user can incite somebody to action according to process requirements
Control to require that realizing computer system in write-in program automatically controls, including emergency disposal journey when exception occurs
Sequence, liquid level defence program as low in wet tank, temperature of liquid hypervisor limit defence program, during unit exception
Defence program, the defence program etc. during liquid feeding volume exception, at utmost improve security of system.
The control of product in liquid adding procedure can be required to coordinate with various processes by this system control program, as
Product temperature during liquid feeding controls to be automatically controlled according to demand by program.Liquid feeding Automated condtrol
Realize, reduce labor intensity and improve the safety of liquid feeding process simultaneously.
5, product quality and yield promote: the Automated condtrol of liquid feeding improves the fine degree of production technology,
Reduce the differences between batches of product, available stay-in-grade different batches product.
Specific to the production of blood products, during its significant advantage is Protein Separation, ethanol adds
Uniform, controllable, reduces the heat of solution that ethanol adding procedure is discharged, and ethanol mixes more uniform with goods,
Making albumin Quality advance, albumin purity raises, and polymer reduces.Due to heavy in ethanol adding procedure
Forming sediment, it is more excellent to be formed, and the globulin response rate gets a promotion.Albumin and the difference between batch of the globulin response rate
Different reduction and tending towards stability.
Accompanying drawing explanation
Fig. 1 is present configuration schematic diagram；
Fig. 2 is the theory diagram of controller；
In figure: 1-wet tank, 2-circulating pump, 3-heat exchanger, 4-refrigerant exit, 5-automatic switch valve
A, 6-coolant import, 7-hands valve B, 8-temperature control valve (TCV), 9-pressure transducer, 10-temperature sensor C,
11-hands valve C, 12-mass flowmenter, 13-flow control valve, 14-automatic switch valve B, 15-ethanol spray
Mouth, 16-filling opening, 17-circulating liquid entrance, 18-overfall, 19-liquid-level switch, 20-level sensing
Device, 21-hands valve A, 22-temperature sensor A, 23-exhaust-valve, 24-pressure-regulating valve, 25-temperature pass
Sensor B, 26-fire-retardant breather valve.
Detailed description of the invention
In order to make the purpose of the present invention, technical scheme and advantage clearer, below in conjunction with accompanying drawing,
The present invention is further elaborated.
As it is shown in figure 1, Automatic Cycle liquid feeding system disclosed by the invention, including wet tank 1, heat exchange
Device 3, circulating pump 2, liquid-consumed branch road and controller, the inlet connection wet tank of circulating pump 2
Liquid outlet, the import of the liquid outlet connection heat exchanger 3 of circulating pump, the outlet of heat exchanger is connected by pipeline
The circulating liquid entrance 17 of wet tank 1, wet tank 1 is provided with temperature sensor A22, liquid level passes
Sensor 20, wet tank 1 top is provided with liquid-level switch 19, overfall 18；Liquid-consumed branch road connects
On the connection pipeline between the outlet and the circulating liquid entrance 17 of wet tank 1 of heat exchanger 3, heat exchange
Arranging temperature sensor B25 on connection pipeline between outlet and the liquid-consumed branch road of device 3, liquid disappears
It is provided with temperature sensor on connection pipeline between consumption branch road and the circulating liquid entrance 17 of wet tank 1
C10, pressure transducer 9 and pressure-regulating valve 24, temperature sensor A22, temperature sensor B25, temperature
Degree sensor C10, pressure transducer 9, pressure-regulating valve 24, liquid level sensor 20, liquid-level switch 19,
Circulating pump 2 is all electrically connected with the controller；Wet tank 1 top is provided with filling opening 16, filling opening 16,
Circulating liquid entrance 17, fire-retardant breather valve 26, liquid outlet is positioned at the bottom of wet tank 1；Heat exchanger 3
Coolant import 6 on be provided with temperature control valve (TCV) 8,3 refrigerant exits 4 of heat exchanger are provided with automatically
Switch valve A5；Mass flowmenter 12 that liquid-consumed branch road includes being sequentially communicated, flow control valve 13,
Automatic switch valve B14 and ethanol nozzle 15, liquid-consumed branch road can have multiple, concrete for 12；
Circulating pump 2 is provided with exhaust-valve 23, and exhaust-valve 23 uses hands valve；The liquid outlet of wet tank 1, change
The coolant import of hot device 3, the porch of liquid-consumed branch road be respectively arranged with hands valve A21, hands valve B7,
Hands valve C11.Temperature control valve (TCV) 8, mass flowmenter 12, flow control valve 13 are all electrically connected with the controller.
As in figure 2 it is shown, controller include CPU, filtering/amplifying circuit, A/D change-over circuit,
D/A change-over circuit, display screen, button；Temperature sensor A, temperature sensor B, temperature sensor C,
Pressure transducer, liquid level sensor, mass flowmenter are all connected with filtering/amplifying circuit, filtering/amplify electricity
Road connects A/D change-over circuit, and described A/D change-over circuit connects CPU, CPU
Connecting D/A change-over circuit, circulating pump, automatic switch valve, liquid-level switch, D/A change-over circuit connects stream
Adjustable valve, temperature control valve (TCV) and pressure-regulating valve, display screen, button are all connected with CPU.
Certainly, the present invention also can have other various embodiments, spiritual and essence without departing substantially from the present invention
In the case of, those of ordinary skill in the art can make various corresponding change and deformation according to the present invention,
But these change accordingly and deform the protection domain that all should belong to appended claims of the invention.
Claims (9)
1. Automatic Cycle liquid feeding system, it is characterised in that: include wet tank, heat exchanger, circulating pump,
Liquid-consumed branch road and controller, the liquid outlet of the inlet connection wet tank of described circulating pump, circulation
The import of the liquid outlet connection heat exchanger of pump, the outlet of described heat exchanger connects wet tank by pipeline
Circulating liquid entrance, described wet tank is provided with temperature sensor A, liquid level sensor and liquid-level switch,
Described liquid-consumed branch road is connected to the company between the outlet of heat exchanger and the circulating liquid entrance of wet tank
On adapter road, liquid-consumed branch road arranges mass flowmenter, flow control valve and automatic switch valve B,
On connection pipeline between outlet and the liquid-consumed branch road of heat exchanger, temperature sensor B, heat exchanger are set
Arrange in coolant input duct and automatic switch valve A is set on temperature control valve (TCV), back liquid pipeline, liquid-consumed
It is provided with temperature sensor C, pressure on connection pipeline between the circulating liquid entrance of branch road and wet tank
Force transducer and pressure-regulating valve, described temperature sensor A, temperature sensor B, temperature sensor C,
Pressure transducer, mass flowmenter, flow control valve, temperature control valve (TCV), pressure-regulating valve, liquid level pass
Sensor, liquid-level switch, circulating pump are all electrically connected with the controller.
Automatic Cycle liquid feeding system the most according to claim 1, it is characterised in that: described controller
Including CPU, filtering/amplifying circuit, A/D change-over circuit, D/A change-over circuit, display screen,
Button；Described temperature sensor A, temperature sensor B, temperature sensor C, pressure transducer, liquid level
Sensor, mass flowmenter are all connected with filtering/amplifying circuit, and described filtering/amplifying circuit connects A/D and turns
Changing circuit, described A/D change-over circuit connects CPU, and described CPU connects D/A
Change-over circuit, circulating pump, automatic switch valve, liquid-level switch, described D/A change-over circuit connection traffic is adjusted
Joint valve, temperature control valve (TCV) and pressure-regulating valve, described display screen, button are all connected with CPU.
Automatic Cycle liquid feeding system the most according to claim 1, it is characterised in that: described liquid stores up
Tank is provided with filling opening, and described filling opening, circulating liquid entrance are respectively positioned on wet tank top, described in go out
Liquid mouth is positioned at the bottom of wet tank.
Automatic Cycle liquid feeding system the most according to claim 1, it is characterised in that: described liquid disappears
The end of consumption branch road connects ethanol nozzle.
Automatic Cycle liquid feeding system the most according to claim 1, it is characterised in that: described liquid disappears
Consumption branch road has 12.
Automatic Cycle liquid feeding system the most according to claim 1, it is characterised in that: described liquid stores up
Tank top is provided with overfall.
Automatic Cycle liquid feeding system the most according to claim 1, it is characterised in that: described liquid stores up
Tank top is provided with fire-retardant breather valve.
Automatic Cycle liquid feeding system the most according to claim 1, it is characterised in that: described liquid stores up
The liquid outlet of tank, the coolant import of heat exchanger, the porch of liquid-consumed branch road are provided with hands valve.
Automatic Cycle liquid feeding system the most according to claim 1, it is characterised in that: described circulating pump
Being provided with exhaust-valve, described exhaust-valve is hands valve.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610536606.6A CN106000148B (en) | 2016-07-08 | 2016-07-08 | Automatic cycle liquid feeding system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610536606.6A CN106000148B (en) | 2016-07-08 | 2016-07-08 | Automatic cycle liquid feeding system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106000148A true CN106000148A (en) | 2016-10-12 |
| CN106000148B CN106000148B (en) | 2019-01-18 |
Family
ID=57108979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610536606.6A Active CN106000148B (en) | 2016-07-08 | 2016-07-08 | Automatic cycle liquid feeding system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106000148B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107056882A (en) * | 2017-03-15 | 2017-08-18 | 上海朗脉洁净技术股份有限公司 | A kind of full-automatic ethanol add-on system produced for blood product |
| CN107678320A (en) * | 2017-11-27 | 2018-02-09 | 中山路得斯空调有限公司 | A kind of printing equipment cleaning agent automatically matches machine controller |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1482942A (en) * | 2000-09-22 | 2004-03-17 | - | Method and device for processing a set of liquid |
| US20140360606A1 (en) * | 2013-06-10 | 2014-12-11 | Robert James Law | Passive Injection of a Chemical Solution into a Process Stream |
| CN204237657U (en) * | 2014-11-18 | 2015-04-01 | 华瑞制药有限公司 | For the aseptic preparation facilities without chlorine water coolant of food, medicine |
| CN205797001U (en) * | 2016-07-08 | 2016-12-14 | 成都蓉生药业有限责任公司 | Automatic Cycle liquid feeding system |
-
2016
- 2016-07-08 CN CN201610536606.6A patent/CN106000148B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1482942A (en) * | 2000-09-22 | 2004-03-17 | - | Method and device for processing a set of liquid |
| US20140360606A1 (en) * | 2013-06-10 | 2014-12-11 | Robert James Law | Passive Injection of a Chemical Solution into a Process Stream |
| CN204237657U (en) * | 2014-11-18 | 2015-04-01 | 华瑞制药有限公司 | For the aseptic preparation facilities without chlorine water coolant of food, medicine |
| CN205797001U (en) * | 2016-07-08 | 2016-12-14 | 成都蓉生药业有限责任公司 | Automatic Cycle liquid feeding system |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107056882A (en) * | 2017-03-15 | 2017-08-18 | 上海朗脉洁净技术股份有限公司 | A kind of full-automatic ethanol add-on system produced for blood product |
| CN107056882B (en) * | 2017-03-15 | 2023-06-06 | 上海朗脉洁净技术股份有限公司 | Full-automatic ethanol adding system for blood product production |
| CN107678320A (en) * | 2017-11-27 | 2018-02-09 | 中山路得斯空调有限公司 | A kind of printing equipment cleaning agent automatically matches machine controller |
| CN107678320B (en) * | 2017-11-27 | 2023-10-24 | 广东路得斯环境科技有限公司 | Full-automatic proportioning machine controller for cleaning agent of printing equipment |
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| Publication number | Publication date |
|---|---|
| CN106000148B (en) | 2019-01-18 |
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