CN105998185A - Antipyretic gel - Google Patents

Antipyretic gel Download PDF

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Publication number
CN105998185A
CN105998185A CN201610494500.4A CN201610494500A CN105998185A CN 105998185 A CN105998185 A CN 105998185A CN 201610494500 A CN201610494500 A CN 201610494500A CN 105998185 A CN105998185 A CN 105998185A
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CN
China
Prior art keywords
percent
antipyretic
antipyretic gel
gel
essential oil
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Pending
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CN201610494500.4A
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Chinese (zh)
Inventor
罗银根
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HUBEI BOKANG PHARMACEUTICAL TECHNOLOGY Co Ltd
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HUBEI BOKANG PHARMACEUTICAL TECHNOLOGY Co Ltd
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Priority to CN201610494500.4A priority Critical patent/CN105998185A/en
Publication of CN105998185A publication Critical patent/CN105998185A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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Abstract

The invention relates to antipyretic gel. The antipyretic gel is prepared from the following raw materials in percentage by mass: 20-45 percent of alcohol, 2-10 percent of propylene glycol, 5-20 percent of menthol, 8-15 percent of plant essential oil, 1-30 percent of borneol, 10-40 percent of xanthan gum and 2-10 percent of methyl 4-hydroxybenzoate sodium. The antipyretic gel has the beneficial effects that rosemary is added to abate fever and achieve the effects of tranquilizing, calming and restoring consciousness; the combination of menthol and plant essential oil has a remarkable antipyretic effect; and the humectant is added to achieve the effect of deep moistening, so that the drug duration is longer. The antipyretic gel has the advantages of being safe, comfortable, cooling, refreshing, convenient and the like.

Description

A kind of antipyretic gel
Technical field
The present invention relates to pharmaceutical technology field, particularly relate to a kind of antipyretic gel.
Background technology
It is known that cause the reason of fever a lot, especially children fever treatment gets up to bother especially, Because of children's torso physiogeny the most not exclusively, before not finding the reason causing fever, it is impossible to simply Use drug for abating fever to treat, the most easily cover the state of an illness, impact further treatment.Therefore, mesh What front fever less than 38.5 DEG C was advocated is to use Physical temperature-lowering mode to bring down a fever.Prior art is commonly used clinically Possess that physical cold is treated, the product brought down a fever is defervescence plaster used or viscose glue of bringing down a fever.
Although existing antipyretic gel uses certain effect, but there is shortcoming, ingredient Relatively low and single, effect of bringing down a fever is not fine.
Summary of the invention
The technical problem to be solved is to provide a kind of effective antipyretic gel of bringing down a fever.
The technical scheme is that a kind of antipyretic gel, by following quality The raw material of percentage ratio prepares: ethanol 20%-45%, propylene glycol 2%-10%, Mentholum 5%-20%, plant essence Oil 8%-15%, Borneolum Syntheticum 1%-30%, xanthan gum 10%-40%, sodium methyl phydroxybenzoate 2%-10%.
The invention has the beneficial effects as follows: add Herba Rosmarini Officinalis, calmness can be played while treatment is brought down a fever Calm the nerves, the effect of refreshment；Mentholum coordinates with plants essential oil, and effect of bringing down a fever is notable；Add wetting agent, Deeply preserving moisture, the sustained drug time is longer；The most also there are safety and comfort, refrigerant frankness, convenient and swift Etc. advantage.
On the basis of technique scheme, the present invention can also do following improvement.
Further, the raw material of following mass percent prepare: ethanol 30%-45%, propylene glycol 4%-8%, Mentholum 8%-15%, plants essential oil 8%-12%, Borneolum Syntheticum 5%-15%, xanthan gum 15%-30%, to hydroxyl Benzoate sodium 3%-7%.
Further, the mass percent of plants essential oil is 10%.
Further, the mass percent of sodium methyl phydroxybenzoate is 5%.
Further, plants essential oil by Herba Rosmarini Officinalis, Herba Schizonepetae, the quintessence oil of Rhizoma Chuanxiong form.
Detailed description of the invention
Being described principle and the feature of the present invention below in conjunction with embodiment, example is served only for explaining The present invention, is not intended to limit the scope of the present invention.
Embodiment one: a kind of antipyretic gel, is prepared by the raw material of following mass percent: ethanol 35%, Propylene glycol 6%, Mentholum 10%, plants essential oil 9%, Borneolum Syntheticum 16%, xanthan gum 18%, para hydroxybenzene first Acid esters sodium 6%.
Embodiment two: a kind of antipyretic gel, is prepared by the raw material of following mass percent: ethanol 40%, Propylene glycol 5%, Mentholum 10%, plants essential oil 10%, Borneolum Syntheticum 10%, xanthan gum 20%, para hydroxybenzene first Acid esters sodium 5%.
Plants essential oil by Herba Rosmarini Officinalis, Herba Schizonepetae, the quintessence oil of Rhizoma Chuanxiong form.
Plants essential oil can also add the quintessence oil of one or several plants following in addition: Flos Matricariae chamomillae, rose Rare, Folium Artemisiae Argyi, Herba Pogostemonis, Camellia sinensis, Lignum Santali Albi, Fructus Citri Limoniae, Radix Angelicae Sinensis, Herba Ephedrae, Ramulus Cinnamomi, Styrax, Folium Perillae Leaf, lavandula angustifolia, Flos Chrysanthemi Indici, Cortex Cinnamomi, Flos Caryophylli, Folium eucalypti globueli (Eucalyptus globulus Labill.), Herba Pelargonii Graveolentis, Radix Bupleuri, Radix Scutellariae, Rhizoma Coptidis, Radix Saposhnikoviae, Herba thymi vulgaris, Fructus Forsythiae, Rhizoma Zingiberis Recens, Flos Lonicerae, Pericarpium Citri Reticulatae, Fructus Hippophae, Rhizoma Et Radix Notopterygii.
Ethanol is good organic solvent, and has stronger osmosis, and Mentholum, Borneolum Syntheticum are dissolved in second In alcohol, can strengthen bring down a fever, cooling effect.Organic solvent propylene glycol has moisture-keeping function, makes antipyretic gel Nice and cool lubrication after external.
Herba Rosmarini Officinalis has tranquillizing and allaying excitement, refreshment effect it can also be used to treatment insomnia, cardiopalmus, have a headache, disappear Changing the multiple diseases such as bad, external can treat wound and arthritis.Also have strong heart, promote metabolism, The blood circulation etc. promoting peripheral vessel acts on.
Rhizoma Chuanxiong, acrid in the mouth, temperature, cure mainly activating QI to alleviate the depression, method wind-dryness is wet, promoting blood circulation and stopping pain.Control air-cooled headache rotation Dizzy, hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.For the moon Through uncomfortable, amenorrhea dysmenorrhea, abdominal mass stomachache, breast side of body twinge, tumbling and swelling, headache, rheumatic arthralgia.
Herba Schizonepetae, taste is flat, and warm in nature, nontoxic, faint scent is dense.Herba Schizonepetae is diaphoresis, antipyretic, is that China is normal With one of medical herbs, can town expectorant, dispel the wind, removing heat from blood.Control influenza, headache cold and heat diaphoresis, vomiting.
Mentholum is reasonably combined with plants essential oil, has the work of dispelling wind and heat pathogens, heat-clearing and toxic substances removing, anti-inflammatory analgetic With, there is for bringing down a fever good curative effect, and the purpose for the treatment of both the principal and secondary aspects of a disease can be reached.
Sodium methyl phydroxybenzoate is as preservative.
Xanthan gum is a kind of monospore polysaccharide produced by false yellow sporangium fermentation, owing to its macromole is special Property, structure and colloid property, and there is several functions, collect emulsifying, suspension, thickening, moisturizing, infiltration Deng in one, bionical lubrication, superior performance, and the thickening characteristic possessed due to xanthan gum itself, make Obtain in the present invention and need not add various thickening agent, and make solution itself possess certain viscosity, can be made this Various compositions in invention are the most persistently distributed, and uniformly play effect, non-stimulated to human body, avirulence.
Owing to antipyretic gel is external preparation for skin product, it is not involved in microcirculation in human body, not impairing the liver kidney, continues thing Reason cooling, protects brain, during use, by corresponding proportion mix and blend, gel is placed in forehead, the sun Cave or DAZHUI acupoint etc. skin surface is smeared back and forth, and each position can be smeared 3 to 4 times repeatedly.For accelerating Cooling rate, can be applied in simultaneously axillary fossa, inside the knee, the position such as thigh and medial leg.
Although above it has been shown and described that embodiments of the invention, it is to be understood that above-mentioned enforcement Example is exemplary, it is impossible to being interpreted as limitation of the present invention, those of ordinary skill in the art is at this Above-described embodiment can be changed in bright scope, revise, replace and modification.

Claims (5)

1. an antipyretic gel, it is characterised in that prepared by the raw material of following mass percent:
Ethanol 20%-45%, propylene glycol 2%-10%, Mentholum 5%-20%, plants essential oil 8%-15%, ice Sheet 1%-30%, xanthan gum 10%-40%, sodium methyl phydroxybenzoate 2%-10%.
A kind of antipyretic gel the most according to claim 1, it is characterised in that by following quality hundred The raw material of proportion by subtraction prepares: ethanol 30%-45%, propylene glycol 4%-8%, Mentholum 8%-15%, plants essential oil 8%-12%, Borneolum Syntheticum 5%-15%, xanthan gum 15%-30%, sodium methyl phydroxybenzoate 3%-7%.
A kind of antipyretic gel the most according to claim 2, it is characterised in that the matter of plants essential oil Amount percentage ratio is 10%.
A kind of antipyretic gel the most according to claim 2, it is characterised in that P-hydroxybenzoic acid The mass percent of ester sodium is 5%.
5. according to described a kind of antipyretic gel arbitrary in claims 1 to 3, it is characterised in that plant Thing quintessence oil by Herba Rosmarini Officinalis, Herba Schizonepetae, the quintessence oil of Rhizoma Chuanxiong form.
CN201610494500.4A 2016-06-29 2016-06-29 Antipyretic gel Pending CN105998185A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106491875A (en) * 2016-11-03 2017-03-15 天津工业大学 A kind of formula of antipyretic gel ballpoint and preparation method
CN106691669A (en) * 2016-12-01 2017-05-24 湖北硅金凝节能减排科技有限公司 Antipyretic gel and roll-on device thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106491875A (en) * 2016-11-03 2017-03-15 天津工业大学 A kind of formula of antipyretic gel ballpoint and preparation method
CN106691669A (en) * 2016-12-01 2017-05-24 湖北硅金凝节能减排科技有限公司 Antipyretic gel and roll-on device thereof

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Application publication date: 20161012