CN105980827B - 生物标本的自动化组织处理及关联技术的背景中的热管理 - Google Patents

生物标本的自动化组织处理及关联技术的背景中的热管理 Download PDF

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CN105980827B
CN105980827B CN201480075469.XA CN201480075469A CN105980827B CN 105980827 B CN105980827 B CN 105980827B CN 201480075469 A CN201480075469 A CN 201480075469A CN 105980827 B CN105980827 B CN 105980827B
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staining
liquid
internal environment
specimen
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CN105980827A (zh
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T.凯勒
M.梅特
C.谢
G.沃德
C.威尔金森
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Ventana Medical Systems Inc
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31Apparatus therefor
    • G01N1/312Apparatus therefor for samples mounted on planar substrates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0822Slides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1838Means for temperature control using fluid heat transfer medium
    • B01L2300/1844Means for temperature control using fluid heat transfer medium using fans
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N2001/302Stain compositions
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00039Transport arrangements specific to flat sample substrates, e.g. pusher blade
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099Characterised by type of test elements
    • G01N2035/00138Slides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178Special arrangements of analysers
    • G01N2035/00306Housings, cabinets, control panels (details)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346Heating or cooling arrangements
    • G01N2035/00356Holding samples at elevated temperature (incubation)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346Heating or cooling arrangements
    • G01N2035/00356Holding samples at elevated temperature (incubation)
    • G01N2035/00376Conductive heating, e.g. heated plates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N2035/00891Displaying information to the operator
    • G01N2035/0091GUI [graphical user interfaces]
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1002Reagent dispensers

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Robotics (AREA)
  • Sampling And Sample Adjustment (AREA)
CN201480075469.XA 2013-12-13 2014-12-08 生物标本的自动化组织处理及关联技术的背景中的热管理 Active CN105980827B (zh)

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US201361916126P 2013-12-13 2013-12-13
US61/916126 2013-12-13
PCT/EP2014/076814 WO2015086485A1 (fr) 2013-12-13 2014-12-08 Gestion thermique dans le contexte de traitement histologique automatisé d'échantillons biologiques et technologie associée

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CN105980827A CN105980827A (zh) 2016-09-28
CN105980827B true CN105980827B (zh) 2021-01-05

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US (1) US10495654B2 (fr)
EP (1) EP3080577B1 (fr)
JP (1) JP6378770B2 (fr)
CN (1) CN105980827B (fr)
AU (1) AU2014363718B2 (fr)
CA (1) CA2932803C (fr)
ES (1) ES2890489T3 (fr)
WO (1) WO2015086485A1 (fr)

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EP4113097A1 (fr) 2013-12-13 2023-01-04 Ventana Medical Systems, Inc. Systèmes de traitement automatisé et procédés pour traiter thermiquement des platines porte-objets de microscope
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DE102015121929A1 (de) * 2015-12-16 2017-06-22 Bit Analytical Instruments Gmbh Verfahren zum Entfernen von Flüssigkeit von einem Objektträger, sowie Objektträger-Transportgestell und Automatisierungssystem dafür
US11460383B2 (en) 2016-06-16 2022-10-04 Nanocytomics, LLC Automated staining system
GB201613173D0 (en) 2016-07-29 2016-09-14 Medical Res Council Electron microscopy
US10238004B2 (en) * 2016-11-07 2019-03-19 Rockwell Automation Technologies, Inc. Controller with enhanced thermal properties
CN110621975A (zh) * 2017-05-24 2019-12-27 文塔纳医疗系统公司 使用平行四边形流的气刀
CN111492224A (zh) * 2017-12-24 2020-08-04 文塔纳医疗系统公司 伊红染色技术
WO2019137980A1 (fr) * 2018-01-11 2019-07-18 Ventana Medical Systems, Inc. Lecteur de codes à barres antibuée
CN109112060B (zh) * 2018-09-13 2021-09-14 青岛大学附属医院 一种微生物样本涂片笔
CN109297793B (zh) * 2018-10-18 2023-12-26 广州安必平医药科技股份有限公司 制片染色一体机
WO2020197819A1 (fr) * 2019-03-22 2020-10-01 Siemens Healthcare Diagnostics Inc. Analyseur d'échantillon biologique à chambre d'air à convection forcée
WO2020197812A1 (fr) 2019-03-22 2020-10-01 Siemens Healthcare Diagnostics Inc. Analyseur d'échantillon biologique avec détection de consommables froids
WO2021262501A1 (fr) * 2020-06-25 2021-12-30 Siemens Healthcare Diagnostics Inc. Analyseur d'échantillon biologique pourvu d'un ajustement automatique thermique de refroidissement en raison de l'altitude
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CN201149563Y (zh) * 2007-11-07 2008-11-12 赵宝忠 生物组织切片恒温染色台
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CN102967499A (zh) * 2012-12-13 2013-03-13 麦克奥迪(厦门)医疗诊断系统有限公司 一种细胞核dna染色方法

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AU2014363718A1 (en) 2016-06-16
AU2014363718B2 (en) 2017-02-23
WO2015086485A1 (fr) 2015-06-18
CA2932803C (fr) 2020-09-08
CN105980827A (zh) 2016-09-28
US10495654B2 (en) 2019-12-03
EP3080577B1 (fr) 2021-07-28
JP2016540223A (ja) 2016-12-22
EP3080577A1 (fr) 2016-10-19
ES2890489T3 (es) 2022-01-20
US20160282376A1 (en) 2016-09-29
JP6378770B2 (ja) 2018-08-22
CA2932803A1 (fr) 2015-06-18

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