CN1059797C - 双氯芬酸钠喷雾剂 - Google Patents
双氯芬酸钠喷雾剂 Download PDFInfo
- Publication number
- CN1059797C CN1059797C CN95112225A CN95112225A CN1059797C CN 1059797 C CN1059797 C CN 1059797C CN 95112225 A CN95112225 A CN 95112225A CN 95112225 A CN95112225 A CN 95112225A CN 1059797 C CN1059797 C CN 1059797C
- Authority
- CN
- China
- Prior art keywords
- diclofenac sodium
- sodium
- spray containing
- tween
- glycerol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229960001193 diclofenac sodium Drugs 0.000 title claims abstract description 22
- JGMJQSFLQWGYMQ-UHFFFAOYSA-M sodium;2,6-dichloro-n-phenylaniline;acetate Chemical compound [Na+].CC([O-])=O.ClC1=CC=CC(Cl)=C1NC1=CC=CC=C1 JGMJQSFLQWGYMQ-UHFFFAOYSA-M 0.000 title claims abstract description 22
- 239000007921 spray Substances 0.000 title claims description 8
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 30
- GEHJYWRUCIMESM-UHFFFAOYSA-L sodium sulfite Chemical compound [Na+].[Na+].[O-]S([O-])=O GEHJYWRUCIMESM-UHFFFAOYSA-L 0.000 claims abstract description 20
- 239000003814 drug Substances 0.000 claims abstract description 10
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 claims abstract description 10
- 229920000053 polysorbate 80 Polymers 0.000 claims abstract description 10
- 235000010265 sodium sulphite Nutrition 0.000 claims abstract description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 9
- 210000000214 mouth Anatomy 0.000 claims abstract description 8
- 239000012153 distilled water Substances 0.000 claims abstract description 7
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 27
- 238000002360 preparation method Methods 0.000 claims description 6
- 201000007100 Pharyngitis Diseases 0.000 claims description 2
- 208000007565 gingivitis Diseases 0.000 claims description 2
- 206010044008 tonsillitis Diseases 0.000 claims description 2
- 206010061218 Inflammation Diseases 0.000 abstract description 3
- 230000000694 effects Effects 0.000 abstract description 2
- 230000004054 inflammatory process Effects 0.000 abstract description 2
- 230000007794 irritation Effects 0.000 abstract description 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 238000005507 spraying Methods 0.000 abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000001525 mentha piperita l. herb oil Substances 0.000 abstract 1
- 235000019477 peppermint oil Nutrition 0.000 abstract 1
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical compound CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 abstract 1
- 229940079593 drug Drugs 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 210000004907 gland Anatomy 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- -1 Oleum menthae Chemical compound 0.000 description 2
- 206010065716 Pharyngeal inflammation Diseases 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- OJIYIVCMRYCWSE-UHFFFAOYSA-M Domiphen bromide Chemical compound [Br-].CCCCCCCCCCCC[N+](C)(C)CCOC1=CC=CC=C1 OJIYIVCMRYCWSE-UHFFFAOYSA-M 0.000 description 1
- 244000246386 Mentha pulegium Species 0.000 description 1
- 235000016257 Mentha pulegium Nutrition 0.000 description 1
- 235000004357 Mentha x piperita Nutrition 0.000 description 1
- IWUCXVSUMQZMFG-AFCXAGJDSA-N Ribavirin Chemical compound N1=C(C(=O)N)N=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 IWUCXVSUMQZMFG-AFCXAGJDSA-N 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 208000036142 Viral infection Diseases 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 229960001859 domiphen bromide Drugs 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 235000001050 hortel pimenta Nutrition 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000012046 mixed solvent Substances 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 235000013772 propylene glycol Nutrition 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 229940124530 sulfonamide Drugs 0.000 description 1
- 150000003456 sulfonamides Chemical class 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 229940100050 virazole Drugs 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Description
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN95112225A CN1059797C (zh) | 1995-11-22 | 1995-11-22 | 双氯芬酸钠喷雾剂 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN95112225A CN1059797C (zh) | 1995-11-22 | 1995-11-22 | 双氯芬酸钠喷雾剂 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1150541A CN1150541A (zh) | 1997-05-28 |
| CN1059797C true CN1059797C (zh) | 2000-12-27 |
Family
ID=5079416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN95112225A Expired - Lifetime CN1059797C (zh) | 1995-11-22 | 1995-11-22 | 双氯芬酸钠喷雾剂 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1059797C (zh) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20020986A1 (it) * | 2002-05-10 | 2003-11-10 | Acraf | Composizione a base di diclofenac per il trattamento topico di affezioni del cavo orofaringeo |
| CN101269058B (zh) * | 2007-03-20 | 2010-09-29 | 郭德 | 一种含双氯芬酸的喷雾剂及其用途 |
| ITMI20121205A1 (it) | 2012-07-11 | 2014-01-12 | Glycores 2000 Srl | Composizione con attivita' antinfiammatoria ed analgesica da somministrare per uso esterno mediante vaporizzazione |
| CN112972385B (zh) * | 2021-02-26 | 2022-03-29 | 广东同德药业有限公司 | 一种消炎镇痛气雾剂及其制备方法 |
-
1995
- 1995-11-22 CN CN95112225A patent/CN1059797C/zh not_active Expired - Lifetime
Non-Patent Citations (1)
| Title |
|---|
| 实用医学杂志11,3 1995.3.1 宁苛从双大 栓的13解 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1150541A (zh) | 1997-05-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: YANGPU HUAHAI PHARMACEUTICAL MATERIALS CO., LTD. Free format text: FORMER OWNER: WANG SHULI Effective date: 20030718 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20030718 Address after: 578101 Industrial Zone, Yangpu Economic Development Zone, Hainan, 5 Patentee after: Huahai Medicine Material Co., Ltd., Yangpu Address before: 250002 5-2-2, six mile south road, Ji'nan, Shandong, 7 Patentee before: Wang Shuli |
|
| C56 | Change in the name or address of the patentee |
Owner name: YANGPU WITHUB MEDICAL CO., LTD. Free format text: FORMER NAME: YANGPU HUAHAI MEDICAL MATERIAL CO., LTD. |
|
| CP03 | Change of name, title or address |
Address after: Yangpu Economic Development Zone of Hainan Province, Hong Kong Road Jinlan mall A204 room Patentee after: Yangpu Huigu Pharmaceutical Co., Ltd. Address before: No. 5, industrial zone, Yangpu Economic Development Zone, Hainan Patentee before: Huahai Medicine Material Co., Ltd., Yangpu |
|
| ASS | Succession or assignment of patent right |
Owner name: JINGWEI PHARMACEUTICAL CO., LTD., SHANDONG Free format text: FORMER OWNER: YANGPU HUIGU PHARMACEUTICAL CO.,LTD. Effective date: 20100819 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 578101 ROOM A204, JINLAN SHOP, GANGBEI ROAD, YANGPU ECONOMIC DEVELOPMENT ZONE, HAINAN PROVINCE TO: 271000 MIDDLE SECTION, CHUANGYE STREET, NEW+HIGH TECHNOLOGY INDUSTRY DEVELOPMENT AREA, TAIAN CITY, SHANDONG PROVINCE |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20100819 Address after: 271000 middle section of pioneering street, Tai'an hi tech Industrial Development Zone, Shandong Patentee after: Jingwei Pharmaceutical Co., Ltd., Shandong Address before: Yangpu Economic Development Zone in Hainan province 578101 Hong Kong Road Jinlan mall A204 room Patentee before: Yangpu Huigu Pharmaceutical Co., Ltd. |
|
| CX01 | Expiry of patent term |
Granted publication date: 20001227 |
|
| EXPY | Termination of patent right or utility model | ||
| DD01 | Delivery of document by public notice |
Addressee: Mao Dexiang Document name: Notification of Expiration of Patent Right Duration |