CN1059663A - The xian-le power compound method of treatment epilepsy - Google Patents

The xian-le power compound method of treatment epilepsy Download PDF

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Publication number
CN1059663A
CN1059663A CN 91106233 CN91106233A CN1059663A CN 1059663 A CN1059663 A CN 1059663A CN 91106233 CN91106233 CN 91106233 CN 91106233 A CN91106233 A CN 91106233A CN 1059663 A CN1059663 A CN 1059663A
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powder
phenobarbital
compound method
medicine
treatment
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CN 91106233
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CN1024499C (en
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邹广杰
吴宏
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Abstract

The present invention relates to the compound method of oral drugs, specifically a kind of powder preparation method for the treatment of epileptics.It is to send hothouse respectively with Chinese herbal medicine Radix Salviae Miltiorrhizae 1-3 part, Radix Astragali 1-3 part, Rhizoma Gastrodiae 0.5-1 part, Bombyx Batryticatus 0.5-1 part, Ramulus Uncariae Cum Uncis 0.6-0.7 part, is under the 80-90 ℃ of condition after continuous drying 70-75 hour in temperature, pulverizes the 80-100 mesh sieve; Mixing and stirring is a powder; Other adds and joins phenobarbital, and its powder and phenobarbital powder proportioning are 2.5-10: 0.005-0.06.The medicine of making can impel cerebral cell recovery normal, improve intelligence of patient, and side effect is minimum, and the other system of body is not had any infringement.

Description

The xian-le power compound method of treatment epilepsy
The present invention relates to the compound method of oral drugs, specifically a kind of powder compounding process for the treatment of epileptics.
Essential epilepsy is a kind of disease by brain cell local damage due to the multiple reason, for this kind treatment of diseases, at present mainly be to adopt some antiepileptic Western medicine to suppress the excessive paradoxical discharge of pathological changes brain cell, rather than the problem of focus of solution paradoxical discharge own, be the method that a kind of house originally takes stopgap measures.Some antiepileptics that adopted are Western medicine, and its toxic and side effects is bigger, and intelligence of patient is all had in various degree infringement.And medicine time need reach several years, can not be interrupted, can produce in various degree infringement to the other system of body.For intractable epilepsy the employing operative therapy is also arranged,, can bring new brain tissue damage though original focus is eased.Postoperative still need rely on antiepileptic medicine to keep.
The objective of the invention is the shortcoming at above-mentioned existence, a kind of epilepsy for the treatment of is provided, side effect is minimum, to the compound method of the harmless antiepileptic of other system of body.
Technical essential of the present invention is:
Sending hothouse respectively with Chinese herbal medicine Radix Salviae Miltiorrhizae 1-3 part, Radix Astragali 1-3 part, Rhizoma Gastrodiae 0.5-1 part, Bombyx Batryticatus 0.5-1 part, Ramulus Uncariae Cum Uncis 0.6-0.7 part, is under the 80-90 ℃ of condition after continuous drying 70-75 hour in temperature, pulverizes the 80-100 mesh sieve; Stir by the mixed of respectively distinguishing the flavor of in the last prescription and to be powder; Other adds and joins the phenobarbital powder and be used as medicine, and its powder and phenobarbital powder proportioning are 2.5-10:0.005-0.06.
Adopt the made medicine of the present invention, after taking, can control the outbreak of epileptics, can fundamentally eliminate focus again.Can impel cerebral cell recovery normal, improve intelligence of patient, and side effect be minimum, the other system of body is not had any infringement.Drawing materials conveniently of the used medicine of respectively distinguishing the flavor of, the processing method of powder is simple, is beneficial to the pharmaceutical factory and produces.
Said Bombyx Batryticatus is the silkworm in spring of collecting May, gives birth to after drying and uses; Ramulus Uncariae cum Uncis is to gather March, dries after the steaming; The spring fiber crops of Rhizoma Gastrodiae for gathering the 3-4 month, drying, Sucus Zingberis run through section.The Radix Salviae Miltiorrhizae decoction pieces of making a living, the stir-fry of giving up alcohol.The Radix Astragali decoction pieces of making a living is avoided and is processed usefulness.
Give a specific embodiment below:
Get Radix Salviae Miltiorrhizae dry powder 900 grams, Radix Astragali dry powder 900 grams, Ramulus Uncariae Cum Uncis dry powder 450 grams, Rhizoma Gastrodiae dry powder 375 grams, Bombyx Batryticatus dry powder 375 grams, phenobarbitone tablet 18 is restrained powdering.The dry powder that above-mentioned each Chinese medicine is made is divided into 300 bags after mixing and stirring, the phenobarbital powder is divided into 300 bags, respectively obeys a bag at every turn, and per 12 hours clothes once.The consumption of phenobarbital powder is for beginning monthly to successively decrease 1/3 till subtracted (total approximately clothes 15 months) after taking medicine 1 year; In dose serve on 4 years constant, also can continue to take.
Pathological study confirms in recent years: the brain cell necrosis at epilepsy focus center, form local little scar tissue, and capillary tremulous pulse and vein around the cicatrix compressing cause perilesional cerebral cell ischemia and edema.Thereby unusual, the of short duration excessive exaltation discharge of the function of brain cell of ischemia and edema causes epilepsy, and every outbreak once, makes the brain cell of degeneration increase a collection of.Increase the weight of gradually so primary disease shows effect with the growth of duration of seizure, intelligence progressively descends.
The Radix Salviae Miltiorrhizae that the present invention adopts has the blood circulation promoting and blood stasis dispelling function, promotes the absorption of focus scar tissue, improves perilesional blood circulation, alleviates the edema and the ischemia of local brain cell, fundamentally improves the brain cell of degeneration, prevents its paradoxical discharge.Can promote blood operation with the Radix Astragali, collaborative Radix Salviae Miltiorrhizae reaches blood circulation promoting and blood stasis dispelling, improves focus peripheral blood circulation purpose.Bombyx Batryticatus has the function of the eliminating stagnation of passing through; Ramulus Uncariae Cum Uncis has the effect of expansion peripheral vessels.Assist Radix Salviae Miltiorrhizae, the Radix Astragali to reach jointly with this two medicine and dissolve cicatrix, improve cicatrix brain cell blood circulation on every side, impel the degeneration resuming function of brain cell normal, prevent its paradoxical discharge, reach therapeutic purposes.Rhizoma Gastrodiae has the spiritual innervation of obvious inhibition in addition.
Because blood circulation promoting and blood stasis dispelling, eliminating cicatrix needs the regular hour, according to the principle for the treatment of both the principal and secondary aspects of a disease, adds in the scheme and has used low dose of phenobarbital.Its purpose is: do not absorb and before degeneration brain cell blood circulation is not fully improved, suppress its discharge of being overexcited temporarily at scar tissue, prevent the continuation necrosis of brain cell, for the thorough treatment of Chinese medicine is raced against time.Because phenobarbital dosage is less, and short treating period, the Chinese medicine that still has can be offset its side effect, so its side effect is very little.
It is for reference to provide formula table below:
Figure 911062335_IMG1
Over 13 years with this side treatment epileptics 576 examples, wherein surpass the course of treatment 24 months be 512 examples, reach the drug withdrawal course of treatment 1.5 years not recurrence be 251 examples, total effective rate reaches 98.73%.

Claims (2)

1, a kind of xian-le power compound method for the treatment of epilepsy, it is characterized in that sending hothouse respectively with Chinese herbal medicine Radix Salviae Miltiorrhizae 1-3 part, Radix Astragali 1-3 part, Rhizoma Gastrodiae 0.5-1 part, Bombyx Batryticatus 0.5-1 part, Ramulus Uncariae Cum Uncis 0.6-0.7 part, in temperature is under the 80-90 ℃ of condition after continuous drying 70-75 hour, pulverizes the 80-100 mesh sieve; Stir by the mixed of respectively distinguishing the flavor of in the last prescription and to be powder; Other adds and joins the phenobarbital powder and be used as medicine, and its powder and phenobarbital powder proportioning are 2.5-10: 0.005-0.06.
2, according to the described compound method of claim 1, it is characterized in that said Bombyx Batryticatus is the silkworm in spring of collecting May, after drying, give birth to and use; Ramulus Uncariae cum Uncis is to gather March, dries after the steaming; The spring fiber crops of Rhizoma Gastrodiae for gathering the 3-4 month, drying, Sucus Zingberis run through section.
CN 91106233 1991-09-07 1991-09-07 Preparation method of "xian-le" for curing of epilepsy Expired - Fee Related CN1024499C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 91106233 CN1024499C (en) 1991-09-07 1991-09-07 Preparation method of "xian-le" for curing of epilepsy

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 91106233 CN1024499C (en) 1991-09-07 1991-09-07 Preparation method of "xian-le" for curing of epilepsy

Publications (2)

Publication Number Publication Date
CN1059663A true CN1059663A (en) 1992-03-25
CN1024499C CN1024499C (en) 1994-05-18

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CN 91106233 Expired - Fee Related CN1024499C (en) 1991-09-07 1991-09-07 Preparation method of "xian-le" for curing of epilepsy

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1051237C (en) * 1994-06-30 2000-04-12 许新升 Meicinal prepn. "Kexianling" for curing epilepsy
CN102579849A (en) * 2012-03-13 2012-07-18 山东仁和堂药业有限公司 Sodium valproate and preparation process thereof
CN111000872A (en) * 2019-11-27 2020-04-14 广东慧达康制药有限公司 Preparation method of ginger and stiff silkworm decoction pieces

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1051237C (en) * 1994-06-30 2000-04-12 许新升 Meicinal prepn. "Kexianling" for curing epilepsy
CN102579849A (en) * 2012-03-13 2012-07-18 山东仁和堂药业有限公司 Sodium valproate and preparation process thereof
CN111000872A (en) * 2019-11-27 2020-04-14 广东慧达康制药有限公司 Preparation method of ginger and stiff silkworm decoction pieces

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