CN105963817A - Integrated module used for intermittent plasma collector - Google Patents
Integrated module used for intermittent plasma collector Download PDFInfo
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- CN105963817A CN105963817A CN201610255561.5A CN201610255561A CN105963817A CN 105963817 A CN105963817 A CN 105963817A CN 201610255561 A CN201610255561 A CN 201610255561A CN 105963817 A CN105963817 A CN 105963817A
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- module
- integration module
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- integration
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/38—Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
- A61M1/382—Optimisation of blood component yield
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
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- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
Abstract
The invention discloses an integrated module used for an intermittent plasma collector. The integrated module is characterized in that connectors are arranged on the integrated module and used for connecting with a collecting module, an anticoagulant module, a gathering module, a separating module, a drug delivery module and an anticoagulant whole blood pump pipe of the collector, wherein a filter cavity and a butterfly cavity are arranged in the integrated module and are connected with the abovementioned modules/pump tubes through connecting channels, and an air monitoring module and a pressure monitoring module are arranged in the integrated module. The integrated module has the beneficial effects that through the integrated arrangement of the modules, the mounting time of an operator is saved, further, the time needed by the reinfusion process during the collecting process is saved, the collecting efficiency is improved, the liquid medicine reinfusion efficiency aiming at the adverse reaction is improved, meanwhile, the running state of the whole device is monitored in real time, and thus the running safety and stability of the device are improved.
Description
Technical field
The present invention relates to a kind of medical apparatus, a kind of integration module being applied on intermittent type sampled plasma device.
Background technology
Sampled plasma needs sampled plasma equipment and collection consumptive material to support the use, and carries out human vein puncture by the blood taking needle of consumptive material
Flowed by liquid such as the blood in collecting device driving consumptive material passage afterwards so that anticoagulated blood enters into and driven height by centrifuge
In the Centrifuge Cup that speed rotates, being centrifuged anticoagulated blood separating, the centrifugal blood plasma obtained enters in blood plasma collecting bag, single
After circulation completes, centrifuge stops operating, and is centrifuged the feedback of component blood in cup, carries out next single cycle after having fed back,
Until gathering the blood plasma of set amount, this kind gathers the method for blood plasma and is referred to as intermittent type collecting flowchart.
Existing intermittent type collecting device and the design of supporting collection consumptive material structure suffer from the drawback that
1. the monitoring modular of acquisition system is many and disperses, and equipment volume is relatively big, and consumptive material installation on each monitoring modular is both needed to hands
Dynamic, limit the efficiency of operator.
2., in gatherer process, need just can be fed back to human body by Centrifuge Cup as run into the medicinal liquid of fat slurry or process untoward reaction,
This flow process reduces collecting efficiency, is unfavorable for alleviating as early as possible the untoward reaction of acquisition target simultaneously.
3., in collecting flowchart, separation module duty lacks pressure monitor means, is unfavorable for that operator grasp collection feelings
Condition.
Summary of the invention
It is an object of the invention to: provide a kind of integration module being applied on intermittent type sampled plasma device, by following skill
Art scheme realizes:
A kind of integration module on intermittent type sampled plasma device, integration module is provided with adopting of joint and harvester
Collection module, anticoagulant module, collection module, separation module, loading module are connected with anticoagulated whole blood pump line, integration module
It is internally provided with filter chamber and butterfly chamber, by interface channel, filter chamber is connected with above-mentioned module/pump line with butterfly chamber, collection
It is provided with air monitering module and pressure monitoring module in becoming module.
As selection, being provided with interface channel and be connected with anticoagulant module by acquisition module in integration module, internal connection leads to
Air monitering module it is provided with on road.
As selection, it is provided with interface channel in integration module and acquisition module is connected with anticoagulated whole blood pump line, interface channel
On be provided with air monitering module and pressure monitoring module.
As selection, butterfly chamber is made up of with right chamber left chamber, is provided with interface channel by left chamber with anti-in integration module
Solidifying whole blood pump line and filter chamber are connected, and are provided with pressure monitoring module in filter chamber.
As selection, it is provided with interface channel in integration module and loading module is connected with right chamber.
As selection, it is provided with interface channel in integration module and right chamber is connected with separation module and collection module.
As selection, it is provided with interface channel in integration module and right chamber is connected with filter chamber, interface channel is provided with
Pressure monitoring module.
As selection, butterfly chamber is connected with each passage by node, connects to be provided with on node and is connected with electronic valve
Through hole.
Present invention is characterized in that
1. by integrated setting, producers are when carrying out assembling product, it is not necessary to the most additionally will be gathered by pipeline or passage
The each parts of device are attached each other, only each parts pipeline need to be inserted the joint that module-external is corresponding, pass through
The passage that inside modules pre-sets can realize connecting between parts, has saved the set-up time of operator, has carried
Rise collecting efficiency.
2. being arranged by integration module internal structure, particularly in integration module, the structure in butterfly chamber arranges and respectively connects node
The setting that is connected with electronic valve of through hole, according to running status, electronic valve is carried out opening and closing regulation, forms difference
Fluid path, make medicinal liquid and fat slurry can no longer via separate cup direct feedback to human body, be greatly saved fat slurry
The feedback time, improve collecting efficiency, make medicinal liquid input as early as possible to acquisition target body, with improper release simultaneously
Reaction.
3. it is provided with air monitering module in integration module, the amount of liquid in anticoagulant branch road is monitored, anti-when monitoring
When solidifying agent branch road has gas to enter, prompting operator change anticoagulant storage device or carry out loop monitoring；Simultaneously
Fluid passage in integration module is monitored by air monitering module, to confirm that the liquid in passage inputs/feeds back
Progress.
4. it is additionally provided with pressure monitoring module in integration module, the blood supply in fluid passage and feedback pressure is monitored, protects
Hindering whole process to carry out in normally-pressured neighbor, as beyond setting value, then prompting operator process；With
Time, pressure in Centrifuge Cup is monitored by pressure monitoring module, it is to avoid in Centrifuge Cup, pressure anomaly causes Centrifuge Cup to leak
Liquid or quick-fried cup.
In sum, the invention has the beneficial effects as follows: by the integrated setting of module, when having saved the installation of operator
Between, save the time required for flow process that feeds back in gatherer process, improve collecting efficiency and the medicinal liquid for untoward reaction returns
Defeated efficiency, carries out implementing monitoring to whole plant running state simultaneously, improves the safety and stablization of plant running.
Accompanying drawing explanation
Fig. 1-Fig. 4 is the internal structure schematic diagram of integration module；
Fig. 5 is the annexation schematic diagram of integration module and each parts of sampled plasma device；
In figure, 1 is integration module, and 2-1 to 2-11 is the first to the 11st joint being arranged on module outer wall, and 3-1 is extremely
3-10 is each joint of connection and the first to the tenth passage of module in module, and 3-11 is for feeding back passage, and 4-1 to 4-3 is first
To the 3rd air monitering module, 5-1 to 5-2 is the first to the second pressure monitoring module, and 6-1 to 6-6 is each passage and mould
The first to the 6th node that block interconnects, 7 is filter chamber, and 8 is blood filter screen, and 9 is butterfly chamber left chamber, and 10 is butterfly
The right chamber in chamber, 11 is blood taking needle, and 12 is three-way connector, 12-1 to 12-3 be three-way connector first to the 3rd branch road,
12-4 is plug joint, and 13-1 is anticoagulant branch road, and 13-2 is anticoagulant pump line, and 13-3 is anticoagulant puncture needle, and 14 are
Anticoagulated whole blood pump line, 15 is centrifugation cup, and 15-1 to 15-2 is separation module the first to the second branch road, and 16 receive for blood plasma
Collection bag, 16-1 for collect branch road, 17 is loading branch road, and 17-1 is loading branch road puncture needle, 18-1 to 18-2 be first to
Second peristaltic pump, 19 is the normally opened through hole in the second pressure detecting module, and 20 is the through hole being connected with electronic valve on node.
Detailed description of the invention
Below in conjunction with specific embodiments and the drawings, the present invention is further illustrated.
With reference to shown in Fig. 1-Fig. 5, it is provided with filter chamber 7 in integration module 1, in filter chamber, is provided with blood filter screen 8；Integrated
It is additionally provided with butterfly chamber in module, is made up of with right chamber 10 left chamber 9；First passage 3-1 it is provided with even in integration module
Meet the tenth joint 2-10 and the first joint 2-1, three-way connector the second branch road 12-2 is connected with anticoagulant pump line 13-2；
It is provided with second channel 3-2 and connects the second joint 2-2 and the 3rd joint 2-3, by anticoagulant branch road 13-1 and anticoagulant pump line
It is connected, makes anticoagulant pass through above-mentioned passage at three-way connector 2 and via the venous blood in blood taking needle 1 acquisition target body
Liquid is mixed into anticoagulated whole blood, inputs integration module by three-way connector the 3rd branch road 12-3, second channel 3-2 is provided with
Whether the first air monitering module 4-1, have gas to enter in being used for monitoring anticoagulant module path, and anticoagulant liquid in path
Amount is the most sufficient；
It is provided with third channel 3-3 in integration module and connects the 4th joint 2-4 and the 11st joint 2-11, by anticoagulated whole blood pump
Pipe 14 is connected with three-way connector the 3rd branch road 12-3, and anticoagulated whole blood pump line is provided with the second peristaltic pump 18-2；Arrange
Have fourth lane 3-4 to connect the 5th joint 2-5 to be connected with left chamber by the 6th node 6-6；It is provided with on third channel
Second air monitering module 4-2 and the first pressure monitoring module 5-1, third channel and fourth lane are blood collection and feed back logical
The important channel in road, the first pressure monitoring module is monitored for the blood supply pressure of acquisition target and the most defeated pressure of liquid,
To ensure to carry out under normal pressure, as beyond setting value, system will be prompted to operator and processes；
It is provided with the tenth passage 3-10 in integration module and connects left chamber and filter chamber by the 3rd node 6-3；It is provided with the 5th
Passage 3-5 connects filter chamber, clematis stem road 3-6 jointing 2-6, feeds back passage 3-11 and is connected by secondary nodal point 6-2
Right chamber, Five-channel, clematis stem road, feedback passage are formed by the normally opened through hole 19 in the second pressure monitoring module 5-2
Intercommunication, the second pressure monitoring module 5-2 is for monitoring the pressure in centrifugation cup 15.
It is provided with the 7th passage 3-7 in integration module and connects primary nodal point 6-1 and the 7th joint 2-7, by separation module second
Road 15-2 is connected with right chamber, is provided with the 8th passage 3-8 and passes through fourth node 6-4, will collect branch road 16-1 and right chamber
Room is connected, and is provided with the 9th passage 3-9 and connects the 5th node 6-5 and the 9th joint 2-9, makes loading branch road 15 and right chamber
Room is connected.
It is provided with the 3rd air monitering module 4-3 in filter chamber 7, feeds back progress for monitoring the blood collection/liquid in passage,
It is provided with the second air monitering module 4-2 on third channel to prevent and standby monitoring as it, when the 3rd air monitering module is sent out
By the second air monitering module as standby monitoring during raw fault.
Three-way connector the first branch road 12-1 is connected with blood taking needle 11, and three-way connector the second branch road 12-2 connects by the tenth
Head 2-10, three-way connector the 3rd branch road 12-3 are connected with integration module respectively by joint 2-11；Anticoagulant branch road 13-1
Connect anticoagulant storage device by puncture needle 13-3, anticoagulant pump line 13-2 is provided with the first peristaltic pump 18-1, passes through
Joint 2-1,2-2 connect integration module, anticoagulated whole blood pump line 14 are provided with the second peristaltic pump 18-2, by the 4th joint
2-4, the 5th joint 2-5 connect integration module；Separation module include centrifugation cup 15 and separation module the first branch road 15-1,
Separation module the second branch road 15-2, separation module the first branch road by joint 2-6, separation module the second branch road 15-2 by the
Seven joint 2-7 connect integration module respectively；Collection module includes blood plasma collecting bag 16 and collects branch road 16-1, collects branch road and leads to
Cross the 8th joint 2-8 and connect integration module；Loading module includes loading branch road 17, and loading branch road passes through loading branch road puncture needle
17-1 connects medicinal liquid storage device, connects integration module by the 9th joint 2-9 simultaneously.
The workflow of the present invention:
1. gather: blood taking needle is acquired the venipuncture of object, makes blood be connected by threeway by the second peristaltic pump effect
Device, with under the first peristaltic pump effect, enters the anticoagulant of three-way connector by anticoagulant branch road-anticoagulant pump line
Enter the 3rd branch road after being mixed into anticoagulated whole blood, enter through third channel-anticoagulated whole blood pump line-fourth lane-left chamber
Enter filter chamber；
2. filter: enter the anticoagulated whole blood of filter chamber after blood strainer filtering, put aside in filter chamber, long-pending full after by the
Five-channel the-the clematis stem road-separation module the first branch road enters centrifugation cup；
3. separate: anticoagulated whole blood, under centrifuge effect, is separated into red blood cell layer, tunica albuginea layer and plasma layer by centrifugation cup,
The plasma layer of density minimum is positioned at separate cup innermost layer；
4. collect: when hold-up in centrifugation cup, blood plasma overflows from Centrifuge Cup, separated module the second branch road-
7th passage enters right chamber, the now closedown of secondary nodal point and the 5th node, blood plasma through fourth node the-the eight passage-
Collect branch road and enter blood plasma collecting bag；
5. blood recovery: after sampled plasma reaches single cycle collection set amount, centrifuge brake stops operating, and is now centrifuged
At the bottom of component blood (erythrocyte and tunica albuginea layer) in separate cup sinks to glass, the second peristaltic pump reversion, make the one-tenth in cup
After dividing the acquired path of blood to be fed back in acquisition target body, enter next one collection and circulate；
6. saline/fat slurry feeds back: when acquisition target generation untoward reaction, and normal saline/medicinal liquid is through loading branch road, and the 9th leads to
Road enters right chamber, now first, fourth node close, the second, the 5th node is opened, and liquid is through secondary nodal point
-the second pressure monitoring module the-the Five-channel-filter chamber-left chamber-fourth lane-anticoagulated whole blood pump line-third channel
-three-way connector three branch roads-blood taking needle is fed back to human body, and when the blood plasma collected is fat slurry, fat is starched also according to upper
State in flow process direct feedback the pure man body, it is not necessary to again through centrifugation cup, saved the feedback time, improved collection
Efficiency；When collecting flowchart enters last collection circulation, blood plasma collecting bag reaches to preset and gathers target, blood recovery
Still remaining fractions blood bottom rear centrifugation cup, now primary nodal point is opened, and normal saline passes through first segment
Separated module the first branch road of point enters centrifugation cup, is taken away by the component blood remained, through anticoagulated whole in separate cup
Blood input path is fed back in human body.
The advantage of this device is: by the integrated setting of module, has saved the set-up time of operator, has saved and adopted
Feed back the time required for flow process during collection, improve collecting efficiency and the medicinal liquid for untoward reaction feeds back efficiency, simultaneously
Whole plant running state is carried out implementing monitoring, improves the safety and stablization of plant running.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all spirit in the present invention and
Any amendment, equivalent and the improvement etc. made within principle, should be included within the scope of the present invention.
Claims (8)
1. the integration module on intermittent type sampled plasma device, it is characterised in that be provided with joint and collection on integration module
The acquisition module of device, anticoagulant module, collection module, separation module, loading module are connected with anticoagulated whole blood pump line,
Integration module is internally provided with filter chamber and butterfly chamber, by interface channel by filter chamber and butterfly chamber and above-mentioned module/pump line
It is connected, in integration module, is provided with air monitering module and pressure monitoring module.
A kind of integration module on intermittent type sampled plasma device, it is characterised in that integration module
Inside it is provided with interface channel to be connected with anticoagulant module by acquisition module, interface channel is provided with air monitering module.
A kind of integration module on intermittent type sampled plasma device, it is characterised in that integration module
Inside be provided with interface channel to be connected with anticoagulated whole blood pump line by acquisition module, interface channel is provided with air monitering module and
Pressure monitoring module.
A kind of integration module on intermittent type sampled plasma device, it is characterised in that butterfly chamber by
Left chamber forms with right chamber, is provided with interface channel and left chamber is connected with anticoagulated whole blood pump line and filter chamber in integration module
Connect, in filter chamber, be provided with pressure monitoring module.
A kind of integration module on intermittent type sampled plasma device, it is characterised in that integration module
Inside it is provided with interface channel to be connected with separation module and collection module by right chamber.
A kind of integration module on intermittent type sampled plasma device, it is characterised in that integration module
Inside it is provided with interface channel loading module to be connected with right chamber.
A kind of integration module on intermittent type sampled plasma device, it is characterised in that integration module
Inside it is provided with interface channel to be connected with filter chamber by right chamber, interface channel is provided with pressure monitoring module.
A kind of integration module on intermittent type sampled plasma device, it is characterised in that connect node
On be provided with the through hole being connected with electronic valve.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610255561.5A CN105963817B (en) | 2016-04-22 | 2016-04-22 | A kind of integration module on intermittent type sampled plasma device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610255561.5A CN105963817B (en) | 2016-04-22 | 2016-04-22 | A kind of integration module on intermittent type sampled plasma device |
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| Publication Number | Publication Date |
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| CN105963817A true CN105963817A (en) | 2016-09-28 |
| CN105963817B CN105963817B (en) | 2018-08-10 |
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| CN201610255561.5A Active CN105963817B (en) | 2016-04-22 | 2016-04-22 | A kind of integration module on intermittent type sampled plasma device |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4146172A (en) * | 1977-10-18 | 1979-03-27 | Baxter Travenol Laboratories, Inc. | Centrifugal liquid processing system |
| EP1674120A1 (en) * | 2004-12-21 | 2006-06-28 | Therakos, Inc. | Method and apparatus for collecting a blood component and performing a photopheresis treatment |
| CN201205379Y (en) * | 2008-05-26 | 2009-03-11 | 四川南格尔生物医学股份有限公司 | Disposable closed single blood-sampling blood cell separator |
| CN204723474U (en) * | 2015-05-08 | 2015-10-28 | 四川南格尔生物科技有限公司 | Blood collection integrating device |
| CN206007686U (en) * | 2016-04-22 | 2017-03-15 | 四川南格尔生物科技有限公司 | A kind of integration module on intermittent type sampled plasma device |
-
2016
- 2016-04-22 CN CN201610255561.5A patent/CN105963817B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4146172A (en) * | 1977-10-18 | 1979-03-27 | Baxter Travenol Laboratories, Inc. | Centrifugal liquid processing system |
| EP1674120A1 (en) * | 2004-12-21 | 2006-06-28 | Therakos, Inc. | Method and apparatus for collecting a blood component and performing a photopheresis treatment |
| CN201205379Y (en) * | 2008-05-26 | 2009-03-11 | 四川南格尔生物医学股份有限公司 | Disposable closed single blood-sampling blood cell separator |
| CN204723474U (en) * | 2015-05-08 | 2015-10-28 | 四川南格尔生物科技有限公司 | Blood collection integrating device |
| CN206007686U (en) * | 2016-04-22 | 2017-03-15 | 四川南格尔生物科技有限公司 | A kind of integration module on intermittent type sampled plasma device |
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| CN105963817B (en) | 2018-08-10 |
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