CN105962952A - Continuous plasma collection method and collection device thereof - Google Patents

Continuous plasma collection method and collection device thereof Download PDF

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Publication number
CN105962952A
CN105962952A CN201610257648.6A CN201610257648A CN105962952A CN 105962952 A CN105962952 A CN 105962952A CN 201610257648 A CN201610257648 A CN 201610257648A CN 105962952 A CN105962952 A CN 105962952A
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branch road
module
blood
anticoagulant
cup
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CN105962952B (en
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孟德颖
黄海涛
王鹏
李川
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Sichuan Nigale Biomedical Inc
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Sichuan Nigale Biomedical Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/150007Details
    • A61B5/150015Source of blood
    • A61B5/15003Source of blood for venous or arterial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/153Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/15Devices for taking samples of blood
    • A61B5/155Devices specially adapted for continuous or multiple sampling, e.g. at predetermined intervals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/38Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Molecular Biology (AREA)
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  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • External Artificial Organs (AREA)

Abstract

The invention discloses a continuous plasma collection method and a collection device thereof; and rapid return of normal saline/medicine liquid/fat pulp is achieved. The plasma collection method and the collection device disclosed by the invention have the beneficial effects that time required by a return process during collecting is saved, and collection efficiency and medicine liquid return efficiency for adverse reactions are improved; and meanwhile, the entire collecting process is monitored, so that the operating safety and stability of the device are improved.

Description

A kind of intermittent type sampled plasma method and its harvester used
Technical field
The present invention relates to a kind of sampled plasma device, and utilize a kind of sampled plasma method that this device realized.
Background technology
Sampled plasma needs sampled plasma equipment and collection consumptive material to support the use, and carries out human vein puncture by the blood taking needle of consumptive material Flowed by liquid such as the blood in collecting device driving consumptive material passage afterwards so that anticoagulated blood enters into and driven height by centrifuge In the Centrifuge Cup that speed rotates, being centrifuged anticoagulated blood separating, the centrifugal blood plasma obtained enters in blood plasma collecting bag, single After circulation completes, centrifuge stops operating, and is centrifuged the feedback of component blood in cup, carries out next single cycle after having fed back, Until gathering the blood plasma of set amount, this kind gathers the method for blood plasma and is referred to as intermittent type collecting flowchart.
There is problems in that in the prior art
1., in gatherer process, need just can be fed back to by centrifugation cup as run into the medicinal liquid of fat slurry or process untoward reaction Human body, this flow process reduces collecting efficiency, is unfavorable for alleviating as early as possible the untoward reaction of acquisition target simultaneously.
2. the monitoring modular of acquisition system is many and disperses, and equipment volume is relatively big, and consumptive material installation on each monitoring modular is both needed to hands Dynamic, limit the efficiency of operator.
3., in collecting flowchart, separation module duty lacks pressure monitor means, is unfavorable for that operator grasp collection feelings Condition.
Summary of the invention
It is an object of the invention to: a kind of sampled plasma device is provided, and utilize a kind of sampled plasma that this device realized Method.
The purpose of the present invention is realized by following technical proposals:
A kind of intermittent type sampled plasma device, including acquisition module, anticoagulant module, separation module, collection module, loading Module, anticoagulated whole blood pump line and integration module, integration module is provided with multiple interface respectively with aforementioned each module and pump line phase Connect, in integration module, be provided with monitoring modular and filter chamber.
As selection, acquisition module includes blood taking needle and three-way connector, and the first branch road of three-way connector is connected with blood taking needle Connecing, second, third branch road is connected with integration module by joint respectively;Anticoagulant module includes anticoagulant pump line and anticoagulant Agent branch road, anticoagulant branch road connects anticoagulant storage device, anticoagulant pump line and anticoagulated whole blood pump line is provided with peristaltic pump; Separation module includes centrifugation cup and separation module first, second branch road;Collection module includes blood plasma collecting bag and collection Road;Loading module includes loading branch road, and loading branch road connects medicinal liquid storage device by puncture needle;It is provided with in integration module Anticoagulant pump line, anticoagulant branch road and three-way connector the second branch road are connected by passage, and this passage is provided with air prison Survey module;It is provided with passage to be connected with three-way connector the 3rd branch road by anticoagulated whole blood pump line simultaneously, this passage is provided with Air monitering module and pressure monitoring module.
As selection, being provided with butterfly chamber in integration module, butterfly chamber is made up of left chamber and right chamber, left chamber and anticoagulant Whole blood pump line and filter chamber are connected, and filter chamber is connected with separation module the first branch road simultaneously;Right chamber and separation module Second branch road, collecting branch road, loading branch road and be connected, right chamber is by feeding back passage and being connected filter chamber and separation module the The passage of one branch road is connected, and this passage is provided with pressure monitoring module;Left and right chamber is connected node with each branch road/passage On be provided with through hole, be connected with electronic valve;Blood filter screen and air monitering module it is provided with in filter chamber.
A kind of intermittent type sampled plasma method, including below scheme:
1) gather: blood taking needle is acquired the venipuncture of object, makes blood pass through three-way connector by the second peristaltic pump effect With under the first peristaltic pump effect, the anticoagulant being entered three-way connector by anticoagulant branch road-anticoagulant pump line is mixed For entering the 3rd branch road after anticoagulated whole blood, enter through third channel-anticoagulated whole blood pump line-fourth lane-left chamber and filter Chamber;
2) filter: the anticoagulated whole blood of entrance filter chamber, after blood strainer filtering, is put aside in filter chamber, by the 5th after amassing completely Passage the-the clematis stem road-separation module the first branch road enters centrifugation cup;
3) separate: anticoagulated whole blood, under centrifuge effect, is separated into component blood and (includes red blood cell layer and tunica albuginea by centrifugation cup Layer) and plasma layer, the plasma layer of density minimum is positioned at separate cup innermost layer;
4) collect: when hold-up in centrifugation cup, blood plasma overflows from Centrifuge Cup, separated module the second branch road-the Seven passages enter right chamber, and now secondary nodal point and the 5th node are closed, and blood plasma is through fourth node the-the eight passages-collection Branch road enters blood plasma collecting bag;
5) component blood feeds back: after sampled plasma reaches single cycle collection set amount, centrifuge brake stops operating, and is now centrifuged At the bottom of erythrocyte in separate cup and tunica albuginea layer sink to glass, the second peristaltic pump reversion, make the acquired road of the component blood in cup Footpath is fed back in acquisition target body, enters the next one and gathers circulation;
6) feeding back: when acquisition target generation untoward reaction, normal saline/medicinal liquid enters right chamber through loading branch road, the 9th path Room, now first, fourth node close, the second, the 5th node is opened, and liquid is supervised through secondary nodal point the-the second pressure Survey module the-the Five-channel-filter chamber-fourth lane-anticoagulated whole blood pump line-third channel-three-way connector the 3rd branch road- Blood taking needle is fed back to human body, when the blood plasma collected is fat slurry, fat slurry also according in above-mentioned flow process direct feedback the pure man body, Without again through centrifugation cup, having saved the feedback time, improved collecting efficiency;Finally adopt when collecting flowchart enters During collection circulation, blood plasma collecting bag reaches to preset and gathers target, still remains part after blood recovery bottom centrifugation cup Component blood, now primary nodal point is opened, and normal saline enters centrifugal point by primary nodal point separated module the second branch road From cup, the component blood remained in separate cup is taken away, be fed back in human body through anticoagulated whole blood input path;
7) monitoring-report to the police: in gatherer process, when monitoring anticoagulant branch road and having gas to enter, prompting operator change anti- Coagulate agent storage device or carry out loop monitoring;When monitoring centrifugation cup pressure anomaly, device stops centrifuge fortune Turn, and each node in closing integration module, suspend collecting flowchart, and point out operator to carry out device inspection.
This device characteristic is:
1. being arranged by integration module internal structure, particularly in integration module, the structure in butterfly chamber arranges and respectively connects node The setting that is connected with electronic valve of through hole, according to by electronic valve is carried out opening and closing regulation, form different liquid Body path, make medicinal liquid and fat slurry can no longer via separate cup direct feedback to human body, be greatly saved the feedback time, Improve collecting efficiency, make medicinal liquid input as early as possible to acquisition target body simultaneously, react with improper release.
2. it is provided with air monitering module in integration module, the amount of liquid in anticoagulant branch road is monitored, anti-when monitoring When solidifying agent branch road has gas to enter, prompting operator change anticoagulant storage device or carry out loop monitoring;Simultaneously Fluid passage in integration module is monitored by air monitering module, to confirm that the liquid in passage inputs/feeds back Progress.
3. it is additionally provided with pressure monitoring module in integration module, the blood supply in fluid passage and feedback pressure is monitored, protects Hindering whole process to carry out in normally-pressured neighbor, as beyond setting value, then prompting operator process;With Time, pressure in centrifugation cup is monitored by pressure monitoring module, it is to avoid in centrifugation cup, pressure anomaly causes Centrifugation cup leakage or quick-fried cup.
The feature of this acquisition method is: achieves medicinal liquid/normal saline/fat by aforementioned means and starches not via centrifugation cup Directly it is fed back to human body by device internal channel, is greatly saved the feedback time, improves collecting efficiency, make medicinal liquid to the greatest extent simultaneously Input soon to acquisition target body, react with improper release.
The invention has the beneficial effects as follows: saved the time required for flow process that feeds back in gatherer process, improve collecting efficiency and Medicinal liquid for untoward reaction feeds back efficiency, whole collecting flowchart is carried out implementing monitoring simultaneously, improves the peace of plant running Complete and stability.
Accompanying drawing explanation
Fig. 1 is the overall structure schematic diagram of this method;
Fig. 2 is each module and the node schematic diagram of integration module;
Fig. 3 is the internal structure schematic diagram of integration module;
Fig. 4 is the schematic rear view of Fig. 3;
Fig. 5 is each connection node and the through hole schematic diagram of the second pressure detecting module;
Fig. 6 is the schematic flow sheet of acquisition method;
Fig. 7 is the contrast schematic diagram of prior art;
In figure, 1 is blood taking needle, and 2 is three-way connector, and 2-1 to 2-3 is respectively three-way connector first to the 3rd branch road, 2-4 is plug joint, and 3-1 is anticoagulant branch road, and 3-2 is anticoagulant pump line, and 3-3 is anticoagulated whole blood pump line;3-4 is for puncturing Pin, 4 is integration module, and 5 is centrifugation cup, and 5-1 to 5-2 is respectively separation module the first to the second branch road, and 6 is blood Slurry collecting bag, 6-1 is for collecting branch road, and 7 is loading branch road, and 7-1 is puncture needle, and 8-1 to 8-2 is the first to the second wriggling Pump, 9-1 to 9-6 is each passage and the first to the 7th node of module interconnection, and 10-1 to 10-11 is for being arranged on mould On block outer wall first is to the 11st joint, and 11-1 to 11-10 is to connect each joint in module to lead to the first to the tenth of module Road, 11-11 is for feeding back passage, and 12 is filter chamber, and 13 is blood filter screen, and 14-1 to 14-3 is the first to the 3rd air prison Surveying module, 15-1 to 15-2 is the first to the second pressure monitoring module, and 16 is butterfly chamber left chamber, and 17 is right chamber, butterfly chamber Room, 18 is the normally opened through hole in the second pressure detecting module, and 19 is the through hole being connected with electronic valve on node.
Detailed description of the invention
Below in conjunction with specific embodiments and the drawings, this method is further described.
With reference to shown in Fig. 1, a kind of intermittent type sampled plasma device, including acquisition module, anticoagulant module, separation module, Collection module, loading module and integration module 4, acquisition module includes blood taking needle 1 and three-way connector 2, three-way connector One branch road 2-1 is connected with blood taking needle 1, and three-way connector the second branch road 2-2 passes through joint 10-10, three-way connector the 3rd Branch road 2-3 is connected with integration module 4 respectively by joint 10-11;Anticoagulant module includes anticoagulant pump line 3-2 and resists Solidifying agent branch road 3-1, anticoagulant branch road 3-1 connect anticoagulant storage device by puncture needle 3-4, and anticoagulant pump line 3-2 sets It is equipped with the first peristaltic pump 8-1, connects integration module 4 by joint 10-1,10-2, anticoagulated whole blood pump line 3-3 is provided with Second peristaltic pump 8-2, connects integration module 4 by joint 10-4,10-5;Separation module includes centrifugation cup 5 and divides From module the first branch road 5-1, separation module the second branch road 5-2, separation module the first branch road 5-1 passes through joint 10-6, separation Module the second branch road 5-2 connects integration module 4 respectively by joint 10-7;Collection module includes blood plasma collecting bag 6 and collects Branch road 6-1, collects branch road 6-1 and connects integration module 4 by joint 10-8;Loading module includes loading branch road 7, and loading props up Road 7 connects medicinal liquid storage device by puncture needle 7-1, connects integration module 4 by joint 10-9 simultaneously.
With reference to shown in Fig. 2-Fig. 4, it is provided with filter chamber 12 in integration module 4, in filter chamber, is provided with blood filter screen 13, collection It is additionally provided with butterfly chamber in becoming module 4, is made up of with right chamber 17 left chamber 16;It is provided with first in integration module 4 to lead to Road 11-1 connects the tenth joint 10-10 and the first joint 10-1, by three-way connector the first branch road 2-1 and anticoagulant pump line 3-2 is connected;It is provided with second channel 11-2 and connects the second joint 10-2 and the 3rd joint 10-3, by anticoagulant branch road 3-1 It is connected with anticoagulant pump line 3-2, makes anticoagulant pass through above-mentioned passage and gather with via blood taking needle 1 at three-way connector 2 Blood in subject is mixed into anticoagulated whole blood, inputs integration module 4, second channel by three-way connector the 3rd branch road 2-3 It is provided with the first air monitering module 14-1 on 11-2, in being used for monitoring anticoagulant module path, whether has gas to enter, and In path, anticoagulant liquid measure is the most sufficient;
It is provided with third channel 11-3 in integration module 4 and connects the 4th joint 10-4 and the 11st joint 10-11, by anticoagulated whole Blood pump pipe 3-3 is connected with three-way connector the 3rd branch road 2-3, and anticoagulated whole blood pump line 3-3 is provided with the second peristaltic pump 8-2; It is provided with fourth lane 11-4 connection the 5th joint 10-5 to be connected with left chamber 16 by the 6th node 9-6;Third channel The second air monitering module 14-2 and the first pressure monitoring module 15-1, third channel 11-3 and four-way it is provided with on 11-3 Road 11-4 is blood collection and the important channel feeding back passage, and the first pressure monitoring module 15-1 is to the blood supply for acquisition target The most defeated pressure of pressure and liquid is monitored, and to ensure to carry out under normal pressure, as beyond setting value, system will carry Show that nurse processes;
It is provided with the tenth passage 11-10 in integration module 4 and connects left chamber 16 and filter chamber 12 by the 3rd node 9-3;If It is equipped with Five-channel 11-5 and connects filter chamber 12, clematis stem road 11-6 jointing 10-6, feed back passage 11-11 and connect the right side Chamber 17, Five-channel 11-5, clematis stem road 11-6, feedback passage 11-11 are by the second pressure monitoring module 15-2 Normally opened through hole 18 form intercommunication, the second pressure monitoring module 15-2 is for monitoring the pressure in centrifugation cup 5;
It is provided with the 7th passage 11-7 in integration module 4 and passes through primary nodal point 9-1 jointing 10-7, by separation module second Branch road 5-2 is connected with right chamber 17, is provided with the 8th passage 11-8 by fourth node 9-4, will collect branch road 6-1 with Right chamber 17 is connected, and is provided with the 9th passage 11-9 and connects the 9th joint 10-9 by the 5th node 9-5, makes loading prop up Road 7 is connected with right chamber 17;
Be provided with the 3rd air monitering module 14-3 in filter chamber 12, for monitor the blood collection/liquid in passage feed back into Degree, third channel is provided with the second air monitering module 14-2 and prevents and standby monitoring as it, when the 3rd air monitering mould By the second air monitering module 14-2 as standby monitoring when block 14-3 breaks down.
As it is shown in figure 5, each node is provided with the through hole 19 being connected with electronic valve on the adjacent position of passage or chamber, Control electronic valve opening and closing by system in integration module, form different fluid paths.
As shown in Figure 6, utilize a kind of intermittent type sampled plasma method that aforementioned intermittent type sampled plasma device is realized, including Following steps:
1. gather: blood taking needle is acquired the venipuncture of object, makes blood be connected by threeway by the second peristaltic pump effect Device, with under the first peristaltic pump effect, enters the anticoagulant of three-way connector by anticoagulant branch road-anticoagulant pump line Enter the 3rd branch road after being mixed into anticoagulated whole blood, enter through third channel-anticoagulated whole blood pump line-fourth lane-left chamber Enter filter chamber;
2. filter: enter the anticoagulated whole blood of filter chamber after blood strainer filtering, put aside in filter chamber, long-pending full after by the Five-channel the-the clematis stem road-separation module the first branch road enters centrifugation cup;
3. separate: anticoagulated whole blood, under centrifuge effect, is separated into red blood cell layer, tunica albuginea layer and plasma layer by centrifugation cup, The plasma layer of density minimum is positioned at separate cup innermost layer;
4. collect: when hold-up in centrifugation cup, blood plasma overflows from Centrifuge Cup, separated module the second branch road- 7th passage enters right chamber, the now closedown of secondary nodal point and the 5th node, blood plasma through fourth node the-the eight passage- Collect branch road and enter blood plasma collecting bag;
5. blood recovery: after sampled plasma reaches single cycle collection set amount, centrifuge brake stops operating, and is now centrifuged At the bottom of erythrocyte in separate cup and tunica albuginea layer sink to glass, the second peristaltic pump reversion, make the component blood in cup acquired Path is fed back in acquisition target body, enters the next one and gathers circulation;
6. feeding back: when acquisition target generation untoward reaction, normal saline/medicinal liquid enters the right side through loading branch road, the 9th path Chamber, now first, fourth node close, the second, the 5th node is opened, and liquid is pressed through secondary nodal point-the second Power monitoring modular the-the Five-channel-filter chamber-fourth lane-anticoagulated whole blood pump line-third channel-three-way connector Three branch roads-blood taking needle is fed back to human body, and when the blood plasma collected is fat slurry, fat slurry also directly returns according to above-mentioned flow process Transport in human body, it is not necessary to again through centrifugation cup, saved the feedback time, improved collecting efficiency;Work as collection Flow process enters last when gathering circulation, and blood plasma collecting bag reaches to preset and gathers target, centrifugation cup after blood recovery Bottom still remains fractions blood, and now primary nodal point is opened, and normal saline passes through the separated module of primary nodal point Second branch road enters centrifugation cup, the component blood remained is taken away in separate cup, returns through anticoagulated whole blood input path Transport in human body;
7. monitoring-report to the police: in gatherer process, when monitoring anticoagulant branch road and having gas to enter, prompting operator change Anticoagulant storage device or carry out loop monitoring;When monitoring centrifugation cup pressure anomaly, device stops centrifugal Machine operates, and each node in closing integration module, suspends collecting flowchart, and points out operator to carry out device inspection.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all spirit in the present invention and Any amendment, equivalent and the improvement etc. made within principle, should be included within the scope of the present invention.

Claims (4)

1. an intermittent type sampled plasma device, it is characterised in that include acquisition module, anticoagulant module, separation module, collect mould Block, loading module, anticoagulated whole blood pump line and integration module, integration module is provided with multiple interface respectively with aforementioned each module And pump line is connected, in integration module, it is provided with monitoring modular and filter chamber.
2. a kind of intermittent type sampled plasma device as claimed in claim 1, it is characterised in that acquisition module includes that blood taking needle and threeway connect Device, the first branch road of three-way connector is connected with blood taking needle, and second, third branch road is respectively by joint and integration module phase Connect;Anticoagulant module includes anticoagulant pump line and anticoagulant branch road, and anticoagulant branch road connects anticoagulant storage device, anticoagulant It is provided with peristaltic pump on agent pump line and anticoagulated whole blood pump line;Separation module includes centrifugation cup and separation module first, second Branch road;Collection module includes blood plasma collecting bag and collects branch road;Loading module includes loading branch road, and loading branch road is by puncturing Pin connects medicinal liquid storage device;Passage it is provided with by anticoagulant pump line, anticoagulant branch road and three-way connector in integration module Second branch road is connected, and this passage is provided with air monitering module;It is provided with passage by anticoagulated whole blood pump line and threeway simultaneously Adapter the 3rd branch road is connected, and this passage is provided with air monitering module and pressure monitoring module.
3. a kind of intermittent type sampled plasma device as claimed in claim 2, it is characterised in that be provided with butterfly chamber, butterfly in integration module Chamber is made up of left chamber and right chamber, and left chamber is connected with anticoagulated whole blood pump line and filter chamber, filter chamber simultaneously with separate Module the first branch road is connected;Right chamber is connected with separation module the second branch road, collection branch road, loading branch road, right chamber It is connected with being connected the filter chamber passage with separation module the first branch road by feeding back passage, this passage is provided with pressure monitoring Module;Left and right chamber is connected on node with each branch road/passage and is provided with through hole, is connected with electronic valve;In filter chamber It is provided with blood filter screen and air monitering module.
4. using a kind of intermittent type sampled plasma method that the intermittent type sampled plasma device described in claim 3 is realized, its feature exists In, including below scheme:
1) gather: blood taking needle is acquired the venipuncture of object, makes blood pass through three-way connector by the second peristaltic pump effect With under the first peristaltic pump effect, the anticoagulant being entered three-way connector by anticoagulant branch road-anticoagulant pump line is mixed For entering the 3rd branch road after anticoagulated whole blood, enter through third channel-anticoagulated whole blood pump line-fourth lane-left chamber and filter Chamber;
2) filter: the anticoagulated whole blood of entrance filter chamber, after blood strainer filtering, is put aside in filter chamber, by the 5th after amassing completely Passage the-the clematis stem road-separation module the first branch road enters centrifugation cup;
3) separate: anticoagulated whole blood, under centrifuge effect, is separated into component blood and (includes red blood cell layer and tunica albuginea by centrifugation cup Layer) and plasma layer, the plasma layer of density minimum is positioned at separate cup innermost layer;
4) collect: when hold-up in centrifugation cup, blood plasma overflows from Centrifuge Cup, separated module the second branch road-the Seven passages enter right chamber, and now secondary nodal point and the 5th node are closed, and blood plasma is through fourth node the-the eight passages-collection Branch road enters blood plasma collecting bag;
5) component blood feeds back: after sampled plasma reaches single cycle collection set amount, centrifuge brake stops operating, and is now centrifuged At the bottom of erythrocyte in separate cup and tunica albuginea layer sink to glass, the second peristaltic pump reversion, make the acquired road of the component blood in cup Footpath is fed back in acquisition target body, enters the next one and gathers circulation;
6) feeding back: when acquisition target generation untoward reaction, normal saline/medicinal liquid enters right chamber through loading branch road, the 9th path Room, now first, fourth node close, the second, the 5th node is opened, and liquid is supervised through secondary nodal point the-the second pressure Survey module the-the Five-channel-filter chamber-fourth lane-anticoagulated whole blood pump line-third channel-three-way connector the 3rd branch road- Blood taking needle is fed back to human body, when the blood plasma collected is fat slurry, fat slurry also according in above-mentioned flow process direct feedback the pure man body, Without again through centrifugation cup, having saved the feedback time, improved collecting efficiency;Finally adopt when collecting flowchart enters During collection circulation, blood plasma collecting bag reaches to preset and gathers target, still remains part after blood recovery bottom centrifugation cup Component blood, now primary nodal point is opened, and normal saline enters centrifugal point by primary nodal point separated module the second branch road From cup, the component blood remained in separate cup is taken away, be fed back in human body through anticoagulated whole blood input path;
7) monitoring-report to the police: in gatherer process, when monitoring anticoagulant branch road and having gas to enter, prompting operator change anti- Coagulate agent storage device or carry out loop monitoring;When monitoring centrifugation cup pressure anomaly, device stops centrifuge fortune Turn, and each node in closing integration module, suspend collecting flowchart, and point out operator to carry out device inspection.
CN201610257648.6A 2016-04-22 2016-04-22 A kind of intermittent type sampled plasma method and its acquisition device used Active CN105962952B (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06285158A (en) * 1993-04-01 1994-10-11 Kawasumi Lab Inc Gravity type device for both blood plasma collection and blood collection
CN204049654U (en) * 2014-06-27 2014-12-31 四川南格尔生物科技有限公司 A kind of novel sampled plasma device
CN204723474U (en) * 2015-05-08 2015-10-28 四川南格尔生物科技有限公司 Blood collection integrating device

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06285158A (en) * 1993-04-01 1994-10-11 Kawasumi Lab Inc Gravity type device for both blood plasma collection and blood collection
CN204049654U (en) * 2014-06-27 2014-12-31 四川南格尔生物科技有限公司 A kind of novel sampled plasma device
CN204723474U (en) * 2015-05-08 2015-10-28 四川南格尔生物科技有限公司 Blood collection integrating device

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