CN105963612A - Traditional Chinese medicine composition for treating diabetes and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating diabetes and preparation method thereof Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine composition for treating diabetes and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 12 to 20 parts of radix ophiopogonis, 5 to 15 parts of herba dendrobii, 5 to 15 parts of semen euryales, 5 to 15 parts of raspberry fruit, 5 to 15 parts of semen cuscutae, 5 to 15 parts of tenodera aridifolia stoll, 6 to 10 parts of sharpleaf galangal fruit, 2 to 6 parts of Chinese gall, 15 to 30 parts of radix astragali seu hedysari, 2 to 6 parts of rhizoma atractylodis, 3 to 8 parts of bighead atractylodes rhizome, 5 to 15 parts of scrophularia ningpoensis, 12 to 20 parts of poria cocos, 5 to 15 parts of radix rehmanniae, 12 to 20 parts of fruit of Chinese wolfberry, and 5 to 10 parts of achyranthes bidentata. The traditional Chinese medicine composition has the advantages that the diabetes is treated by the theory of invigorating qi, nourishing yin, nourishing kidney and generating body fluid; the pertinence is strong, the treatment effect is good, and the effective rate is high.
Description
[technical field]
The present invention relates to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine composition treating diabetes and preparation method thereof.
[background technology]
Diabetes are one group of metabolics being characterized with hyperglycemia caused by defect of insulin secretion or insulin action obstacle
Disease, can cause multiple complications, and persistent high blood sugar is disorderly with long-term metabolic etc. may result in body tissue's organ, particularly eye,
Kidney, cardiovascular and neural infringement and dysfunction thereof and exhaustion, severe patient can cause dehydration, electrolyte disturbance and soda acid
Acute complications ketoacidosis and the Hyperosmotic comas such as dysequilibrium.The clinical manifestation of diabetes is more with person in middle and old age, Major Clinical
It is characterized as polyuria, polydipsia, polyphagia and becomes thin, be i.e. " three-many-one-little "；Situation according to different patients, it is also possible to occur
Dizzy, weak, loss of appetite, Nausea and vomiting, stomachache, polyuria increases the weight of, dizzy, drowsiness, blurred vision, dyspnea,
The different symptoms such as stupor, the health of serious harm middle-aged and elderly people.And along with the development of society, people's living standard significantly carries
Height, the sickness rate of diabetes improves year by year, and diabetes have become one of principal disease of being detrimental to health.At present, treatment sugar
The medicine of urine disease is a lot, but big drug is expensive, and medical expense is high.Treatment still based on chemical synthetic drug, as sulfonamides,
Biguanides, glucosidase inhibitor, Lie Nai and euglycemic agent etc..So chemical classes antidiabetic drug long-term taking not only to liver,
Injury of kidney is relatively big, and easily produces drug resistance.Treat diabetes conditions, giving consideration to both the incidental and fundamental by the means of Chinese medicine, be one
Channel the most leaved for development, treatment aspect has the effect that it is original.
[summary of the invention]
The goal of the invention of the present invention is: for the problem of above-mentioned existence, it is provided that a kind of Chinese medicine composition treating diabetes and
Preparation method, treats diabetes by QI invigorating, yin nourishing, nourishing kidney, the principle promoted the production of body fluid, have that specific aim is high, therapeutic effect is good,
The advantage that effective percentage is high.
The symptom of diabetes can be divided into two big classes: a big class is the performance relevant with metabolism disorder, especially relevant with hyperglycemia
" three-many-one-little ", is more common in type 1 diabetes, and type 2 diabetes mellitus is the most fairly obvious or only has part performance, and another big class is
Various acute, the performances of chronic complicating diseases.Classical symptom: three-many-one-little symptom, i.e. polyuria, polydipsia, polyphagia and become thin；No
Classical symptom: some type 2 diabetes mellitus patients symptomatic be not true to type, the most dizzy, weak etc., the most asymptomatic.Some morbidities are early
Phase or onset diabetes last stage, may occur in which Hypoglycemic symptoms before lunch or dinner；The performance of acute complications: feelings stress waited
Aggravation under condition.May occur in which loss of appetite, Nausea and vomiting, stomachache, polyuria increases the weight of, dizzy, drowsiness, blurred vision,
Dyspnea, stupor etc.；The main performance of chronic complicating diseases: diabetic retinopathy, diabetic nephropathy, diabetes god
Through pathological changes, infection repeatedly.
The Chinese medicine composition prescription of the present invention is developed according to the mechanism of above-mentioned type 1 diabetes disease, and the technical scheme used is as follows:
A kind of Chinese medicine composition treating diabetes, is made up of the raw material of following weight portion: Radix Ophiopogonis 12-20 part, Herba Dendrobii 5-15 part,
Semen Euryales 5-15 part, Fructus Rubi 5-15 part, Semen Cuscutae 5-15 part, Ootheca Mantidis 5-15 part, Fructus Alpiniae Oxyphyllae 6-10 part, Galla Chinensis
2-6 part, Radix Astragali 15-25 part, Rhizoma Atractylodis 2-6 part, Rhizoma Atractylodis Macrocephalae 3-8 part, Radix Scrophulariae 5-15 part, Poria 12-20 part, Radix Rehmanniae 5-15
Part, Fructus Lycii 12-20 part, Radix Achyranthis Bidentatae 5-10 part.
Preferably, the Chinese medicine composition of above-mentioned treatment diabetes is made up of the raw material of following weight portion: Radix Ophiopogonis 14-18 part, Herba Dendrobii 8-12
Part, Semen Euryales 8-12 part, Fructus Rubi 8-12 part, Semen Cuscutae 8-12 part, Ootheca Mantidis 8-12 part, Fructus Alpiniae Oxyphyllae 7-9 part, five times
Sub-3-5 part, Radix Astragali 18-22 part, Rhizoma Atractylodis 3-5 part, Rhizoma Atractylodis Macrocephalae 4-6 part, Radix Scrophulariae 8-12 part, Poria 14-18 part, the Radix Rehmanniae
8-12 part, Fructus Lycii 14-18 part, Radix Achyranthis Bidentatae 6-9 part.
It is highly preferred that the Chinese medicine composition of above-mentioned treatment diabetes is made up of the raw material of following weight portion: Radix Ophiopogonis 16 parts, Herba Dendrobii
10 parts, Semen Euryales 10 parts, Fructus Rubi 10 parts, Semen Cuscutae 10 parts, Ootheca Mantidis 10 parts, Fructus Alpiniae Oxyphyllae 8 parts, Galla Chinensis 4 parts,
The Radix Astragali 20 parts, Rhizoma Atractylodis 4 parts, the Rhizoma Atractylodis Macrocephalae 5 parts, Radix Scrophulariae 10 parts, 16 parts of Poria, 10 parts of the Radix Rehmanniae, Fructus Lycii 16 parts, Radix Achyranthis Bidentatae
8 parts.
The preparation method of the Chinese medicine composition of above-mentioned treatment diabetes, comprises the following steps:
(1) by Semen Euryales, Semen Cuscutae, Ootheca Mantidis, Fructus Alpiniae Oxyphyllae, Galla Chinensis, the Radix Rehmanniae, it is dried, pulverizes, make fine powder；
(2) by Radix Ophiopogonis, Herba Dendrobii, Fructus Rubi, the Radix Astragali, Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Radix Scrophulariae, Poria, Fructus Lycii, Radix Achyranthis Bidentatae, it is dried, powder
It is broken into coarse powder；
(3) coarse powder step (2) prepared, adds 5-10 times amount water soaking 2-4 hour, decocts 1-3 hour；Filter, filter
Slag adds 3-5 times amount water, decocts 1-3 hour；Filtering, merge twice filtrate, filtrate is concentrated into relative density at 70 DEG C and is
The thick paste of 1.10-1.30, drying under reduced pressure, cross 100-200 mesh sieve after pulverizing, obtain uniform fine powder；
(4) pharmaceutical preparation commonly used it is prepared as after fine powder mix homogeneously step (1) and step (3) made.
Preferably, described fine powder was 100-200 mesh sieve and obtained.
Preferably, described coarse powder cross 10-50 mesh sieve and obtain.
The Chinese medicine composition of above-mentioned treatment diabetes can make medicament according to conventional pharmaceutical methods, and the dosage form of medicament can be punching
Agent, tablet, capsule or oral liquid.
The instructions of taking of this Chinese medicine composition is: each take 2-3g, daily three times, and point morning, noon and afternoon take, and within three months, are
One course for the treatment of, take 1-2 the course for the treatment of.
The concrete effect of raw material of Chinese medicine employed in the present invention is as follows:
Radix Ophiopogonis, hardship sweet, micro-, cool.GUIXIN, lung, stomach warp.Yin-nourishing and body fluid promoting, nourishing the lung to arrest cough, clear away heart-fire relieving restlessness.Cure mainly calentura wound
Tianjin, vexed, thirsty, dry pharynx lung-heat, cough, pulmonary tuberculosis.
Herba Dendrobii, sweet in the mouth, cold nature.Energy replenishing YIN and removing heat, reinforcing stomach reg fluid.For consumption of body fluid by heat, low grade fever excessive thirst, the few tongue of red tongue；
Deficiency of stomach-Yin, thirsty and dry pharynx, vomiting eats less, vague epigastralgia, the few tongue of tongue light；Deficiency of kidney yin, blurring of vision.
Semen Euryales, sweet in the mouth, puckery, property is put down.Return spleen, kidney channel.There is supplementing the kidney to control the nocturnal, tonifying spleen and stopping diarrhea, the function of damp eliminating leukorrhagia stopping.Raw
Moral character is put down, puckery and the most stagnant, spleen reinforcing kidney and hold concurrently can damp eliminating.Being usually used in nebulousurine, leukorrhagia, seminal emission, incontinence of urine, the turbid damp person that holds concurrently is outstanding
Preferably.
Fructus Rubi, sweet in the mouth is pungent, and property is put down.Invigorating the liver and kidney, urine reducing, supporing yang, controlling nocturnal emission with astringent drugs, improving eyesight.Control sexual impotence, seminal emission, frequency of micturition,
Incontinence of urine, asthenia, mesh is dark.
Semen Cuscutae, abnormal smells from the patient is pungent, sweet, flat nontoxic.The kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity.The waist knee joint muscles and bones being applicable to deficiency of the liver and kindey is ached,
Legs and feet weakness, impotence and seminal emission, crazy talk, frequent micturition, dripping urination, dizziness and blurred vision, blurring of vision, Hiccough and deaf with
And the disease such as women's leukorrhagia, habitual abortion.
Ootheca Mantidis, sweet, nontoxic, enter liver, kidney channel, bladder warp.Controlling nocturnal emission with astringent drugs reducing urination, reinforcing the kidney and supporting YANG.For emission due to deficiency of the kidney, premature ejaculation,
Sexual impotence, nebulousurine, leukorrhagia.
Fructus Alpiniae Oxyphyllae, acrid in the mouth is bitter, property heat.Enter spleen, kidney channel.Warming the spleen, warming the kidney, solid and gas, arresting seminal emission.Control cold air stomachache, middle vomiting due to pathogenic cold
Rush down, many salivas, seminal emission, dribbling urination, night many urine.
Galla Chinensis, sour in the mouth, puckery, cold in nature.Return lung, large intestine, kidney channel.Astringe the lung；Hidroschesis；Astringing intestine to stop diarrhea；Controlling nocturnal emission with astringent drugs；Hemostasis；Removing toxic substances.
Control chronic cough of deficiency lung, spontaneous sweating, chronic dysentery chronic diarrhea, proctoptosis, pass out semen, nebulousurine, various hemorrhage, carbuncle furuncle.
The Radix Astragali, sweet in the mouth tepor.Return lung, spleen, liver, kidney channel.There is invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation
Effect.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle difficulty is routed,
Bursting for a long time and do not hold back, blood deficiency and yellow complexion, interior-heat is quenched one's thirst.
Rhizoma Atractylodis, pungent, bitter, temperature.Return spleen, stomach, Liver Channel.Drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, let out
Removing water retention by purgation swells, tinea pedis flaccidity, rheumatic arthralgia, anemofrigid cold, nyctalopia.Main the spleen and stomach being stranded by dampness；Asthenia drowsiness；Born of the same parents' painful abdominal mass abdominal distention；Appetite
Depressed；Tell and have loose bowels；Phlegm retention；Damp-edema；Exterior syndrome folder is wet；Head heavy sensation of the body pain；Arthromyodynia warm nature；Podomere is ached and is weighed；Flaccidity folds in a garment.
The Rhizoma Atractylodis Macrocephalae, bitter, sweet, temperature.Return spleen, stomach warp.Invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite,
Abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Radix Scrophulariae is sweet in the mouth, hardship, salty；Cold nature.Return lung, stomach, kidney channel.Clearing away heat and cooling blood, eliminating fire and detoxication, YIN nourishing.Control temperature
Heresy is joined the army, and cave in pericardium, maculae caused by violent heat pathogen, consumption of YIN caused by febrile disease, crimson tongue excessive thirst, Tianjin hinder constipation, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia,
Scrofula, diphtheria, carbuncle sore tumefacting virus.
Poria, property slightly sweet flavor is put down, is entered the heart, lung, spleen channel.There is eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, effect of mind tranquilizing and the heart calming.
The Radix Rehmanniae, sweet in the mouth, hardship, cold nature.GUIXIN, liver, kidney channel.Matter profit fall is let out.There is clearing away heat and cooling blood, merit that tonifying YIN promotes the production of body fluid
Effect.Join the army blood for warming febrile disease, high fever coma, xerostomia crimson tongue.
Fructus Lycii, sweet in the mouth, property is put down.Return Liver Channel, kidney channel, lung meridian.Nourishing the liver, nourishing kidney, lung moistening.Control caused by liver and kidney deficiency, dizzy mesh
Dizzy, the most unclear, soreness of the waist and knees, impotence and seminal emission, cough due to consumptive disease, taking fluids profusely of quenching one's thirst.
Radix Achyranthis Bidentatae, bitter, acid, property is put down.Return liver, kidney channel.Invigorating the liver and kidney, bone and muscle strengthening, promoting blood circulation to restore menstrual flow, ignite (blood) is descending, profit
Urinate treating stranguria.
In sum, owing to have employed technique scheme, the invention has the beneficial effects as follows:
The prescription of the present invention, scientific and reasonable compatibility, it is to develop for type 1 diabetes, has the advantages that the present invention
The Chinese medicine composition of the treatment diabetes provided with Radix Ophiopogonis, Herba Dendrobii, Semen Euryales, Fructus Rubi, Semen Cuscutae, Ootheca Mantidis, Fructus Alpiniae Oxyphyllae,
Galla Chinensis, the Radix Astragali, Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Radix Scrophulariae, Poria, the Radix Rehmanniae, Fructus Lycii, Radix Achyranthis Bidentatae are raw material, wherein Radix Ophiopogonis, Poria can
Clear away heart-fire relieving restlessness, mind tranquilizing and the heart calming；Herba Dendrobii, Radix Scrophulariae, the Radix Rehmanniae can YIN nourishing and the production of body fluid promoting, clearing away heat and cooling blood；The Rhizoma Atractylodis Macrocephalae, the Radix Astragali have the merit of QI invigorating
Effect, Radix Achyranthis Bidentatae can promoting blood circulation to restore menstrual flow；Semen Euryales, Fructus Alpiniae Oxyphyllae, Fructus Lycii can spleen reinforcing lung moistening；Rhizoma Atractylodis invigorating the spleen for eliminating dampness；Fructus Rubi, Semen Cuscutae
Then can the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity；Ootheca Mantidis can controlling nocturnal emission with astringent drugs reducing urination, reinforcing the kidney and supporting YANG；Galla Chinensis can controlling nocturnal emission with astringent drugs removing toxic substances；Above-mentioned raw materials
Effective ingredient cooperates, and jointly plays nourishing YIN and clearing away heat, promoting the production of body fluid to quench thirst, invigorating the spleen and benefiting QI, the liver and the kidney tonifying, blood circulation promoting and blood stasis dispelling, clears away heart-fire
The effect of relieving restlessness, is possible not only to reduce blood glucose, and uses aggregate measures to release diabetics by the method for determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs
Clinical symptoms, prevents and treats the multiple complications of diabetes, and therapeutic effect is notable, can realize treating both the principal and secondary aspects of a disease, safe and reliable, without any
Toxic and side effects.
[detailed description of the invention]
The invention provides a kind of Chinese medicine composition treating diabetes, be made up of the raw material of following weight portion: Radix Ophiopogonis 12-20 part,
Herba Dendrobii 5-15 part, Semen Euryales 5-15 part, Fructus Rubi 5-15 part, Semen Cuscutae 5-15 part, Ootheca Mantidis 5-15 part, Fructus Alpiniae Oxyphyllae 6-10
Part, Galla Chinensis 2-6 part, Radix Astragali 15-25 part, Rhizoma Atractylodis 2-6 part, Rhizoma Atractylodis Macrocephalae 3-8 part, Radix Scrophulariae 5-15 part, Poria 12-20 part,
Radix Rehmanniae 5-15 part, Fructus Lycii 12-20 part, Radix Achyranthis Bidentatae 5-10 part.Kinds of traditional Chinese medicines complements each other, play altogether QI invigorating, yin nourishing, nourishing kidney,
The merit promoted the production of body fluid, and then type 1 diabetes problem can be cured the most accurately and rapidly.Below by way of specific embodiment to this
Invention is described in further detail.
Embodiment 1
A kind of Chinese medicine composition treating diabetes, is made up of the raw material of following weight portion: Radix Ophiopogonis 12 grams, Herba Dendrobii 5 grams, Gorgon euryale
Real 5 grams, Fructus Rubi 5 grams, Semen Cuscutae 5 grams, Ootheca Mantidis 5 grams, Fructus Alpiniae Oxyphyllae 6 grams, Galla Chinensis 2 grams, the Radix Astragali 15 grams, grey
Art 2 grams, the Rhizoma Atractylodis Macrocephalae 3 grams, Radix Scrophulariae 5 grams, 12 grams of Poria, 5 grams of the Radix Rehmanniae, Fructus Lycii 12 grams, Radix Achyranthis Bidentatae 5 grams.
Following method is used to prepare this Chinese medicine composition:
(1) by Semen Euryales, Semen Cuscutae, Ootheca Mantidis, Fructus Alpiniae Oxyphyllae, Galla Chinensis, the Radix Rehmanniae, it is dried, pulverizes, make 100-200 mesh thin
Powder；
(2) by Radix Ophiopogonis, Herba Dendrobii, Fructus Rubi, the Radix Astragali, Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Radix Scrophulariae, Poria, Fructus Lycii, Radix Achyranthis Bidentatae, it is dried, powder
It is broken into 10 mesh coarse powder；
(3) coarse powder step (2) prepared, adds 5 times amount water soaking 2 hours, decocts 1 hour；Filtering, filtering residue adds
3 times amount water, decoct 1 hour；Filtering, merge twice filtrate, it is the thick paste of 1.10 that filtrate is concentrated into relative density at 70 DEG C,
Drying under reduced pressure, crosses 100-200 mesh sieve, obtains uniform fine powder after pulverizing；
(4) pharmaceutical preparation commonly used it is prepared as after fine powder mix homogeneously step (1) and step (3) made.
Embodiment 2
A kind of Chinese medicine composition treating diabetes, is made up of the raw material of following weight portion: Radix Ophiopogonis 14 grams, Herba Dendrobii 8 grams, Gorgon euryale
Real 8 grams, Fructus Rubi 8 grams, Semen Cuscutae 8 grams, Ootheca Mantidis 8 grams, Fructus Alpiniae Oxyphyllae 7 grams, Galla Chinensis 3 grams, the Radix Astragali 18 grams, grey
Art 3 grams, the Rhizoma Atractylodis Macrocephalae 4 grams, Radix Scrophulariae 8 grams, 14 grams of Poria, 8 grams of the Radix Rehmanniae, Fructus Lycii 14 grams, Radix Achyranthis Bidentatae 6 grams.
Following method is used to prepare this Chinese medicine composition:
(1) by Semen Euryales, Semen Cuscutae, Ootheca Mantidis, Fructus Alpiniae Oxyphyllae, Galla Chinensis, the Radix Rehmanniae, it is dried, pulverizes, make 100-200 mesh thin
Powder；
(2) by Radix Ophiopogonis, Herba Dendrobii, Fructus Rubi, the Radix Astragali, Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Radix Scrophulariae, Poria, Fructus Lycii, Radix Achyranthis Bidentatae, it is dried, powder
It is broken into 50 mesh coarse powder；
(3) coarse powder step (2) prepared, adds 8 times amount water soaking 3 hours, decocts 2 hours；Filtering, filtering residue adds
4 times amount water, decoct 2 hours；Filtering, merge twice filtrate, it is the thick paste of 1.20 that filtrate is concentrated into relative density at 70 DEG C,
Drying under reduced pressure, crosses 100-200 mesh sieve, obtains uniform fine powder after pulverizing；
(4) pharmaceutical preparation commonly used it is prepared as after fine powder mix homogeneously step (1) and step (3) made.
Embodiment 3
A kind of Chinese medicine composition treating diabetes, is made up of the raw material of following weight portion: Radix Ophiopogonis 16 grams, Herba Dendrobii 10 grams,
Semen Euryales 10 grams, Fructus Rubi 10 grams, Semen Cuscutae 10 grams, Ootheca Mantidis 10 grams, Fructus Alpiniae Oxyphyllae 8 grams, Galla Chinensis 4 grams, the Radix Astragali 20
Gram, Rhizoma Atractylodis 4 grams, the Rhizoma Atractylodis Macrocephalae 5 grams, Radix Scrophulariae 10 grams, 16 grams of Poria, 10 grams of the Radix Rehmanniae, Fructus Lycii 16 grams, Radix Achyranthis Bidentatae 8 grams.
Following method is used to prepare this Chinese medicine composition:
(1) by Semen Euryales, Semen Cuscutae, Ootheca Mantidis, Fructus Alpiniae Oxyphyllae, Galla Chinensis, the Radix Rehmanniae, it is dried, pulverizes, make 100-200 mesh thin
Powder；
(2) by Radix Ophiopogonis, Herba Dendrobii, Fructus Rubi, the Radix Astragali, Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Radix Scrophulariae, Poria, Fructus Lycii, Radix Achyranthis Bidentatae, it is dried, powder
It is broken into 20 mesh coarse powder；
(3) coarse powder step (2) prepared, adds 10 times amount water soaking 4 hours, decocts 3 hours；Filtering, filtering residue adds
5 times amount water, decoct 3 hours；Filtering, merge twice filtrate, it is the thick paste of 1.30 that filtrate is concentrated into relative density at 70 DEG C,
Drying under reduced pressure, crosses 100-200 mesh sieve, obtains uniform fine powder after pulverizing；
(4) pharmaceutical preparation commonly used it is prepared as after fine powder mix homogeneously step (1) and step (3) made.
Embodiment 4
A kind of Chinese medicine composition treating diabetes, is made up of the raw material of following weight portion: Radix Ophiopogonis 20 grams, Herba Dendrobii 15 grams,
Semen Euryales 15 grams, Fructus Rubi 15 grams, Semen Cuscutae 15 grams, Ootheca Mantidis 15 grams, Fructus Alpiniae Oxyphyllae 10 grams, Galla Chinensis 6 grams, the Radix Astragali
25 grams, Rhizoma Atractylodis 6 grams, the Rhizoma Atractylodis Macrocephalae 8 grams, Radix Scrophulariae 15 grams, 20 grams of Poria, 15 grams of the Radix Rehmanniae, Fructus Lycii 20 grams, Radix Achyranthis Bidentatae 10
Gram.
The method identical with embodiment 3 is used to prepare this Chinese medicine composition.
Embodiment 5
A kind of Chinese medicine composition treating diabetes, is made up of the raw material of following weight portion: Radix Ophiopogonis 18 grams, Herba Dendrobii 12 grams,
Semen Euryales 12 grams, Fructus Rubi 12 grams, Semen Cuscutae 12 grams, Ootheca Mantidis 12 grams, Fructus Alpiniae Oxyphyllae 9 grams, Galla Chinensis 5 grams, the Radix Astragali 22
Gram, Rhizoma Atractylodis 5 grams, the Rhizoma Atractylodis Macrocephalae 6 grams, Radix Scrophulariae 12 grams, 18 grams of Poria, 12 grams of the Radix Rehmanniae, Fructus Lycii 18 grams, Radix Achyranthis Bidentatae 9 grams.
The method identical with embodiment 3 is used to prepare this Chinese medicine composition.
In order to observe the clinical efficacy of present composition treatment diabetes, the present invention is carried out Preliminary Clinical Observation, now faced
Bed result of the test is reported as follows:
(1) object of observation: during in January, 2016-June, uses the Chinese medicine composition of the present invention to treat 89 example patients altogether,
Man's 52 examples, female 37 example, 59.3 ± 8.3 years old age, the course of disease 5.1 ± 2.3.
(2) diagnostic criteria: polyuria, polydipsia, polyphagia, muscle power and weight loss, skin pruritus, visual deterioration, numb hand and foot,
Palpitation and short breath, diarrhoea constipation, urine retention and sexual impotence etc..
(3) Therapeutic Method: arbitrary Chinese medicine composition made in oral embodiment of the present invention 1-5, each takes 2-3g, every day
Taking three times, point morning, noon and afternoon take, and within three months, are a course for the treatment of, take 1-2 the course for the treatment of, follow up a case by regular visits to after six months, statistics recurrence
Situation.
(4) the standard of curative effect evaluation:
It is effective: clinical symptoms is improved substantially, and soreness of the waist and knees, fatigue and weak, dry mouth and throat, nocturia etc. disappear or substantially disappear,
Blood sugar level fluctuated within normal range, and blood pressure≤128/80mmHg, 24h urine protein ＜ 30mg, blood urea nitrogen and creatinine are equal
It is down to normal level.
Effective: clinical symptom relief, soreness of the waist and knees, fatigue and weak, dry mouth and throat, nocturia etc. be improved significantly, empty
Abdomen glycemic control is preferable, and fluctuation of blood pressure all has decline at about 140/90mmHg, 24h urine protein and blood urea nitrogen creatinine, but not
Take a turn for the better completely.
Invalid: clinical symptoms is improved inconspicuous, blood pressure and blood glucose without declining or having decline but undesirable, 24h urine protein quantitation and
Blood urea nitrogen creatinine does not all decline, or declines not up to effective standard.
(5) therapeutic outcome: in 89 example cases, through 1-2 course of therapy, the most effective 55 examples, effective 29 examples, invalid 5
Example, total effective rate 94.4%, the course for the treatment of is the shortest three months, the longest six months, follows up a case by regular visits to 1 year have no recurrence.
Model case:
King so-and-so, 53 years old, man, within nearly 3 months, without obvious inducement conscious xerostomia polydipsia, and frequent micturition, dreaminess symptom, Yi Xin occur
Vexatious unbearably, random thoughts dizziness, be diabetes after diagnosing.Taking the Chinese medicine composition of the present invention afterwards, after 1 month, symptom is obvious
Improving, after taking 2 courses for the treatment of, symptom is cured.
Huang, female, 51 years old, nearly half a year without obvious inducement occur thirsty, polydipsia, polyuria, nocturia 3-4 time, polyorexia,
Weak, it is diabetes after diagnosing, takes Chinese medicine composition two weeks of the present invention, symptom has alleviated, after persistently taking 2 courses for the treatment of,
Transference cure, is cured.
Described above is the detailed description for the preferable possible embodiments of the present invention, but embodiment is not limited to the special of the present invention
Profit application range, the equal change completed under the technical spirit suggested by all present invention or modification change, the present invention all should be belonged to
Contained the scope of the claims.
Claims (6)
1. the Chinese medicine composition treating diabetes, it is characterised in that: be made up of the raw material of following weight portion: Radix Ophiopogonis 12-20
Part, Herba Dendrobii 5-15 part, Semen Euryales 5-15 part, Fructus Rubi 5-15 part, Semen Cuscutae 5-15 part, Ootheca Mantidis 5-15 part, Fructus Alpiniae Oxyphyllae
6-10 part, Galla Chinensis 2-6 part, Radix Astragali 15-25 part, Rhizoma Atractylodis 2-6 part, Rhizoma Atractylodis Macrocephalae 3-8 part, Radix Scrophulariae 5-15 part, Poria 12-20
Part, Radix Rehmanniae 5-15 part, Fructus Lycii 12-20 part, Radix Achyranthis Bidentatae 5-10 part.
A kind of Chinese medicine composition treating diabetes the most according to claim 1, it is characterised in that: by following weight portion
Raw material is made: Radix Ophiopogonis 14-18 part, Herba Dendrobii 8-12 part, Semen Euryales 8-12 part, Fructus Rubi 8-12 part, Semen Cuscutae 8-12 part,
Ootheca Mantidis 8-12 part, Fructus Alpiniae Oxyphyllae 7-9 part, Galla Chinensis 3-5 part, Radix Astragali 18-22 part, Rhizoma Atractylodis 3-5 part, Rhizoma Atractylodis Macrocephalae 4-6 part,
Radix Scrophulariae 8-12 part, Poria 14-18 part, Radix Rehmanniae 8-12 part, Fructus Lycii 14-18 part, Radix Achyranthis Bidentatae 6-9 part.
A kind of Chinese medicine composition treating diabetes the most according to claim 1, it is characterised in that: by following weight portion
Raw material is made: Radix Ophiopogonis 16 parts, Herba Dendrobii 10 parts, Semen Euryales 10 parts, Fructus Rubi 10 parts, Semen Cuscutae 10 parts, Ootheca Mantidis 10 parts,
Fructus Alpiniae Oxyphyllae 8 parts, Galla Chinensis 4 parts, the Radix Astragali 20 parts, Rhizoma Atractylodis 4 parts, the Rhizoma Atractylodis Macrocephalae 5 parts, Radix Scrophulariae 10 parts, 16 parts of Poria, the Radix Rehmanniae
10 parts, Fructus Lycii 16 parts, Radix Achyranthis Bidentatae 8 parts.
4. according to the preparation method of a kind of Chinese medicine composition treating diabetes described in claim 1-3 any one, its feature
It is: comprise the following steps:
(1) by Semen Euryales, Semen Cuscutae, Ootheca Mantidis, Fructus Alpiniae Oxyphyllae, Galla Chinensis, the Radix Rehmanniae, it is dried, pulverizes, make fine powder；
(2) by Radix Ophiopogonis, Herba Dendrobii, Fructus Rubi, the Radix Astragali, Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Radix Scrophulariae, Poria, Fructus Lycii, Radix Achyranthis Bidentatae, it is dried, powder
It is broken into coarse powder；
(3) coarse powder step (2) prepared, adds 5-10 times amount water soaking 2-4 hour, decocts 1-3 hour；Filter, filter
Slag adds 3-5 times amount water, decocts 1-3 hour；Filtering, merge twice filtrate, filtrate is concentrated into relative density at 70 DEG C and is
The thick paste of 1.10-1.30, drying under reduced pressure, cross 100-200 mesh sieve after pulverizing, obtain uniform fine powder；
(4) pharmaceutical preparation commonly used it is prepared as after fine powder mix homogeneously step (1) and step (3) made.
The preparation method of a kind of Chinese medicine composition treating diabetes the most according to claim 4, it is characterised in that: described
Fine powder was 100-200 mesh sieve and obtained.
The preparation method of a kind of Chinese medicine composition treating diabetes the most according to claim 4, it is characterised in that: described
Coarse powder cross 10-50 mesh sieve and obtain.
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Citations (3)
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| CN104740469A (en) * | 2013-12-30 | 2015-07-01 | 华克宁 | Traditional Chinese medicine prescription for treating diabetes |
| CN105169078A (en) * | 2015-10-20 | 2015-12-23 | 吴国鑫 | Traditional Chinese medicinal composition for treating diabetes |
| CN105250758A (en) * | 2015-10-20 | 2016-01-20 | 吴国鑫 | Traditional Chinese medicine composition for treating diabetes |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104740469A (en) * | 2013-12-30 | 2015-07-01 | 华克宁 | Traditional Chinese medicine prescription for treating diabetes |
| CN105169078A (en) * | 2015-10-20 | 2015-12-23 | 吴国鑫 | Traditional Chinese medicinal composition for treating diabetes |
| CN105250758A (en) * | 2015-10-20 | 2016-01-20 | 吴国鑫 | Traditional Chinese medicine composition for treating diabetes |
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