CN105963551A - Prescription for treating skin diseases - Google Patents

Abstract

The invention belongs to the technical field of medicines and provides a prescription for treating skin diseases. The prescription is prepared from the following raw materials in parts by weight: 20 to 25 parts of common threewingnut root, 20 to 24 parts of rhizoma picrorhizae, 10 to 12 parts of betel nuts, 10 to 12 parts of radix paeoniae alba, 8 to 10 parts of Chinese angelica, 15 to 20 parts of herba cayratica jeponicae, 20 to 24 parts of cactuses, 20 to 24 parts of cortex dictamni, 10 to 12 parts of herba schizonepetae, 10 to 12 parts of radix saposhnikoviae, 8 to 10 parts of radix paeoniae rubrathe, 20 to 24 parts of radix geutianae, 10 to 12 parts of radix sophorae flavescentis, 15 to 20 parts of cortex phellodendri, 15 to 20 parts of nelumbium speciosum, 15 to 20 parts of fresh radix rehmanniae, 10 to 12 parts of radix lithospermi, 10 to 12 parts of herba senecionis scandentis, 15 to 20 parts of camphor, 15 to 20 parts of radix semiaquilegiae, 10 to 12 parts of honeysuckle flowers, 15 to 20 parts of radix tinosporae, 15 to 20 parts of fructus physalis, 15 to 20 parts of radix sophorae subprostratae, 15 to 20 parts of cortex fraxini, 15 to 20 parts of radix pulsatillae, 10 to 12 parts of radix ampelopsis, 10 to 12 parts of pseudobulbus cremastrae, 10 to 12 parts of herba orostachyos and 5 to 10 parts of borneol. With the adoption of the technical scheme, the problem of a traditional Chinese medicine formula in the prior art that the pharmaceutical effect is poor is solved.

Description

One treats dermopathic prescription

Technical field

The invention belongs to pharmaceutical technology field, relate to a kind of dermopathic prescription of eutherapeutic treatment.

Background technology

Dermatitis refers to general term, not an independent disease of the dermal inflammatory illness caused by the infection of various inside and outside portions or non-infectious factor, and its cause of disease and complicated clinical manifestation are various, and atoipc dermatitis is endogenous dermatitis.Traditional atoipc dermatitis external medicine, its function is the most single, and therapeutic effect and cost performance are not ideal enough, it is difficult to meets most skin patient and wishes rapid healing and the requirement without any sequela.

Therefore, the prescription of a kind of eutherapeutic treatment atoipc dermatitis or necessary is invented.

Summary of the invention

The present invention proposes one and treats dermopathic prescription, the problem solving prior art prescription weak curative effect.

The technical scheme is that and be achieved in that:

One treats dermopathic prescription,

It is made up of the raw material of following weight proportioning:

Radix Tripterygii Wilfordii 20-25, Rhizoma Picrorhizae 20-24, Semen Arecae 10-12, Radix Paeoniae Alba 10-12, Radix Angelicae Sinensis 8-10, Herba Cayatiae Japonicae 15-20, Radix et Caulis Opuntiae Dillenii 20-24, Cortex Dictamni 20-24, Herba Schizonepetae 10-12, Radix Saposhnikoviae 10-12, Radix Paeoniae Rubra 8-10, Radix Gentianae 20-24, Radix Sophorae Flavescentis 10-12, Cortex Phellodendri 15-20, the red lotus 15-20 of drought, Radix Rehmanniae 15-20, Radix Arnebiae (Radix Lithospermi) 10-12, Herba Senecionis Scandentis 10-12, Camphora 15-20, Radix Semiaquilegiae 15-20, Flos Lonicerae 10-12, Radix Tinosporae 15-20, Calyx seu Fructus physalis 15-20, Radix Sophorae Tonkinensis 15-20, Cortex Fraxini 15-20, Radix Pulsatillae 15-20, Radix Ampelopsis 10-12, Pseudobulbus Cremastrae Seu Pleiones 10-12, Herba Orostachyos 10-12, Borneolum Syntheticum 5-10.

Preferably, the quality proportioning of each raw material is:

Radix Tripterygii Wilfordii 24, Rhizoma Picrorhizae 22, Semen Arecae 11, the Radix Paeoniae Alba 11, Radix Angelicae Sinensis 8, Herba Cayatiae Japonicae 17, Radix et Caulis Opuntiae Dillenii 22, Cortex Dictamni 22, Herba Schizonepetae 10, Radix Saposhnikoviae 11, Radix Paeoniae Rubra 9, Radix Gentianae 24, Radix Sophorae Flavescentis 11, Cortex Phellodendri 18, non-irrigated red lotus 19, Radix Rehmanniae 18, Radix Arnebiae (Radix Lithospermi) 11, Herba Senecionis Scandentis 12, Camphora 17, Radix Semiaquilegiae 16, Flos Lonicerae 10, Radix Tinosporae 18, Calyx seu Fructus physalis 17, Radix Sophorae Tonkinensis 18, Cortex Fraxini 17, the Radix Pulsatillae 17, Radix Ampelopsis 11, Pseudobulbus Cremastrae Seu Pleiones 11, Herba Orostachyos 12, Borneolum Syntheticum 8.

Radix Tripterygii Wilfordii has expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, reducing swelling and alleviating pain, effect of removing toxic substances parasite killing.Treating lepra reaction, rheumatoid arthritis etc. with it clinically, pharmacological research also indicates that it has antitumor, antiinflammatory etc. to act on.Radix Tripterygii Wilfordii also has immunoregulation effect, gas alkaloid can suppress the formation of antibody, also improves microcirculatory effect, can distend the blood vessels, thus increase blood flow.The present invention mainly utilizes Radix Tripterygii Wilfordii blood circulation promoting, antiinflammatory, improves the effect of skin environment.

Rhizoma Picrorhizae is Scrophulariaceae herbaceos perennial, similar to Rhizoma Coptidis title, and is the product of clearing up internal heat by using drugs of bitter in taste and cold in nature dampness, is apt to, except gastrointestinal is damp and hot, be all the good medicine controlling damp-heat dysentery.Perennial herb, hairiness.Rhizome is cylindrical, slightly carries wooden, long 15-20cm.Rhizoma Picrorhizae is apt to reducing the asthenic fever, dispelling fever with infantile malnutrition；Rhizoma Coptidis is then apt to clearing away heart-fire, rushes down stomach-fire, for removing toxic substances key medicine.The present invention mainly utilizes the effect of Rhizoma Picrorhizae heat clearing away, and with Semen Arecae, the Radix Paeoniae Alba, Radix Angelicae Sinensis collocation, effect is more preferable.

Herba Cayatiae Japonicae heat-clearing and toxic substances removing, for laryngopharynx swelling and pain, acute mastitis, furuncle carbuncle sore, corneal nebula, erysipelas, mumps, dysentery, skin trauma, snakeworm stings；Radix et Caulis Opuntiae Dillenii mainly has the functions such as heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, promoting flow of QI and blood, benefiting stomach and stopping pain, additionally, Radix et Caulis Opuntiae Dillenii can remove the thick horny layer of skin, has the effect of skin whitening, accelerates skin rehabilitation speed.

Cortex Dictamni controls all pyretic toxicity wind, aversion to wind, wind skin ulcer, scabies are red rotten, and eyebrow loss of hairs is crisp, musculus cutaneus is anxious, high fever aversion to cold, principal solution heat Huang, wine Huang, acute jaundice, yellow, the labor Huang of paddy etc., there is the most antipruritic, anti-allergic effects, rubella caused by wind heat noxious dampness, eczema, scabies, jaundice, damp-heat arthralgia, wind-repellent itching-relieving, arranges in pairs or groups with Herba Schizonepetae, Radix Saposhnikoviae, Radix Paeoniae Rubra, more preferable to dermatosis.

Radix Gentianae heat clearing and damp drying, for jaundice due to damp-heat, pudendal pruritus swelling of the vulva, frequent micturition, leukorrhagia, eczema, removes damp-heat in lower-JIAO etc., and with Radix Sophorae Flavescentis, Cortex Phellodendri collocation, clearing heat and expelling damp is better.

The red lotus heat-clearing and toxic substances removing of drought, blood circulation promoting and blood stasis dispelling；Radix Rehmanniae clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting: send out macule for epidemic febrile disease, high heat, crimson tongue, body, preferable to dermatosis curative effect；Radix Arnebiae (Radix Lithospermi) removing heat from blood moves back rash, enters nutrient blood, the absurd row of epidemic febrile disease pathogenic heat forcing blood, measles for epidemic febrile disease heat；Herba Senecionis Scandentis is used for pyretic toxicity or damp-heat dysentery.

Camphora is the branch of canella Camphor tree, dry, leaf and root, through refining the crystalline particulate prepared.Camphora has orifice opening, qi stagnation removing, wards off foul, effect of killing parasites for relieving itching, reducing swelling and alleviating pain, cures mainly the symptoms such as scabies pruritus, traumatic pain, toothache, has slight local anesthetic action to skin, slow down dermopathic sense of discomfort.

Radix Semiaquilegiae heat-clearing and toxic substances removing, arranges in pairs or groups with Flos Lonicerae, suppresses scytitis, eliminates toxicity；Radix Tinosporae heat-clearing and toxic substances removing, has obvious antiinflammatory action to immune inflammation, and Calyx seu Fructus physalis also has elimination dermal toxicity, increases skin rehabilitation efficiency；Radix Sophorae Tonkinensis, heat-clearing and toxic substances removing；Cortex Fraxini has heat clearing away, removing fire from the liver effect.

The Radix Pulsatillae is called: how grass, powder silkweed, Bai Toucao, Lao Gucao, chrysanthemum chrysanthemum Seedling, Lao Wenghua, be always preced with flower, ram's horn flower, Lao Gonghua, Mao aunt piece flower.Bitter in the mouth, cold in nature.Return stomach, large intestine channel.There is heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, antibacterial, analgesia, disinsection efficiency.

Pseudobulbus Cremastrae Seu Pleiones, sweet, micro-pungent, cold.Return liver, stomach, spleen channel.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, for excess-heat carbuncle, carbuncle furunculosis, scrofula tuberculosis, innominate toxic swelling.Herba Orostachyos heat-clearing and toxic substances removing, hemostasis, dampness removing, detumescence, control haematemesis, epistaxis, dysentery, hepatitis, malaria, pyretic stranguria, hemorrhoid, eczema, carbuncle poison, furuncle, soup fire is burnt.

Radix Arnebiae (Radix Lithospermi) removing heat from blood and promoting blood circulation, rash of detoxifying；Radix Ampelopsis heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, blood activating and promoting tissue regeneration, removing toxic substances rash, bacteriostasis antibiosis, moreover it is possible to strengthen collagen protein synthesis；Borneolum Syntheticum, property is arduous, clearing heat for detumescence, antipruritic pain relieving.

Radix Saposhnikoviae has expelling pathogenic wind from the body surface, removing dampness to relieve pain, spasmolytic, antipruritic effect, and the present invention mainly utilizes Radix Saposhnikoviae to suppress inflammatory cell, and effect combing of timid wind, relieving exterior syndrome has the skin problem that inside causes, the simultaneously reflection of suppression part skin allergy.

Present invention have the beneficial effect that

The present invention, to atoipc dermatitis good effect, uses Chinese medicine formula entirely, will not cause the dependency of skin, being experimentally verified that, effect is notable, safety good, can effectively treat atoipc dermatitis, treat skin erythema, edema that dermatitis causes, be that one can effectively treat dermopathic effective Traditional Chinese medicinal prescription.

Detailed description of the invention

Technical scheme in the embodiment of the present invention will be clearly and completely described below, it is clear that described embodiment is only a part of embodiment of the present invention rather than whole embodiments.Based on the embodiment in the present invention, the every other embodiment that those of ordinary skill in the art are obtained under not making creative work premise, broadly fall into the scope of protection of the invention.

Embodiment 1: one treats dermopathic prescription, is made up of the raw material of following weight proportioning:

Radix Tripterygii Wilfordii 20, Rhizoma Picrorhizae 20, Semen Arecae 10, the Radix Paeoniae Alba 10, Radix Angelicae Sinensis 8, Herba Cayatiae Japonicae 15, Radix et Caulis Opuntiae Dillenii 20, Cortex Dictamni 20, Herba Schizonepetae 10, Radix Saposhnikoviae 10, Radix Paeoniae Rubra 8, Radix Gentianae 20, Radix Sophorae Flavescentis 10, Cortex Phellodendri 15, non-irrigated red lotus 15, Radix Rehmanniae 15, Radix Arnebiae (Radix Lithospermi) 10, Herba Senecionis Scandentis 10, Camphora 15, Radix Semiaquilegiae 15, Flos Lonicerae 10, Radix Tinosporae 15, Calyx seu Fructus physalis 15, Radix Sophorae Tonkinensis 15, Cortex Fraxini 15, the Radix Pulsatillae 15, Radix Ampelopsis 10, Pseudobulbus Cremastrae Seu Pleiones 10, Herba Orostachyos 10, Borneolum Syntheticum 5.

Embodiment 2: Radix Tripterygii Wilfordii 24, Rhizoma Picrorhizae 22, Semen Arecae 11, the Radix Paeoniae Alba 11, Radix Angelicae Sinensis 8, Herba Cayatiae Japonicae 17, Radix et Caulis Opuntiae Dillenii 22, Cortex Dictamni 22, Herba Schizonepetae 10, Radix Saposhnikoviae 11, Radix Paeoniae Rubra 9, Radix Gentianae 24, Radix Sophorae Flavescentis 11, Cortex Phellodendri 18, non-irrigated red lotus 19, Radix Rehmanniae 18, Radix Arnebiae (Radix Lithospermi) 11, Herba Senecionis Scandentis 12, Camphora 17, Radix Semiaquilegiae 16, Flos Lonicerae 10, Radix Tinosporae 18, Calyx seu Fructus physalis 17, Radix Sophorae Tonkinensis 18, Cortex Fraxini 17, the Radix Pulsatillae 17, Radix Ampelopsis 11, Pseudobulbus Cremastrae Seu Pleiones 11, Herba Orostachyos 12, Borneolum Syntheticum 8.

Embodiment 3: Radix Tripterygii Wilfordii 25, Rhizoma Picrorhizae 24, Semen Arecae 12, the Radix Paeoniae Alba 12, Radix Angelicae Sinensis 10, Herba Cayatiae Japonicae 20, Radix et Caulis Opuntiae Dillenii 24, Cortex Dictamni 24, Herba Schizonepetae 12, Radix Saposhnikoviae 12, Radix Paeoniae Rubra 10, Radix Gentianae 24, Radix Sophorae Flavescentis 12, Cortex Phellodendri 20, non-irrigated red lotus 20, Radix Rehmanniae 20, Radix Arnebiae (Radix Lithospermi) 12, Herba Senecionis Scandentis 12, Camphora 20, Radix Semiaquilegiae 20, Flos Lonicerae 12, Radix Tinosporae 20, Calyx seu Fructus physalis 20, Radix Sophorae Tonkinensis 20, Cortex Fraxini 20, the Radix Pulsatillae 20, Radix Ampelopsis 12, Pseudobulbus Cremastrae Seu Pleiones 12, Herba Orostachyos 12, Borneolum Syntheticum 10.

Clinical trial 1:

1.1 description of test

Collect 200 patients altogether, it is randomly divided into: embodiment 1 group 50, embodiment 2 groups 50, embodiment 3 groups 50 and matched group 50 groups, age of four groups of patients, the state of an illness, the course of disease is compared, statistical procedures, difference nonsignificance, two groups of cases have comparability.

1.2 experimental technique

Embodiment 1 group: the prescription smeared in the embodiment of the present invention 1 every 12 hours, two weeks courses for the treatment of.

Embodiment 2 groups: the prescription smeared in the embodiment of the present invention 2 every 12 hours, two weeks courses for the treatment of.

Embodiment 3 groups: the prescription smeared in the embodiment of the present invention 3 every 12 hours, two weeks courses for the treatment of.

Matched group: be left intact.

To red swelling of the skin before and after treatment, itch, the symptom such as decortication is observed.

1.3 experimental result

1.3.1 criterion of therapeutical effect

Recovery from illness: clinical symptoms all disappears, and drug withdrawal has no recurrence in one week.

Effective: clinical symptoms substantially alleviates.

Effective: clinical symptom relief.

Invalid: clinical symptoms is without being clearly better or increasing the weight of.

1.3.2 therapeutic outcome is shown in Table 1

1 four groups of comparitive study of table

As seen from the above table, atoipc dermatitis can safely and effectively be treated by the medicine that the present invention prepares, the symptom such as skin erythema that treatment dermatitis causes, edema, pruritus.

Test 2 materials and methods:

2.1 animal packets:

Take healthy albino guinea-pig 24, be randomly divided into 4 groups by sex body weight, often group 6, male and female half and half, respectively embodiment 1 group, embodiment 2 groups, embodiment 3 groups, blank group.

2.2 experimental techniques:

In testing the previous day, the routine depilation of guinea pig back both sides, lose hair or feathers scope 3cm × 3cm, observes local skin intact unbroken after losing hair or feathers 24 hours, experiment uses self compares on the right side of same Guinea Pig Left, left side embrocates embodiment 1 prescription, embodiment 2 prescription, embodiment 3 prescription respectively, and pure water comparison, the blank group not side of applying medicinal lotion or ointment are wiped in right side, do blank, every 4 hours each coatings once, smear continuously three times, observe with warm water cleaning medicine-feeding part after 24 hours.

2.3 observation index

After cleaning topical, perusal in 24,48,72 hours recording medicine position are with or without erythema and edema situation, calculate each point of observation by table 1 and respectively organize the mean scores of Cavia porcellus, carry out stimulus intensity evaluation by table 2, observe Cavia porcellus diet, defecation, active situation etc. simultaneously.

Table 1 skin wound repair standards of grading

Table 2 skin irritation intensity evaluation standard

2.4 experimental result

Table 2 experimental result contrast table

Owing to the skin physiology of Cavia porcellus is similar to that the skin of people, still select Cavia porcellus to do skin irritation test.More than test result indicate that, user, to no skin irritation, will be caused skin to endanger by the prescription in the present invention.

In sum, prescription in the present invention is to atoipc dermatitis good effect, entirely use Chinese medicine formula, the dependency of skin will not be caused, being experimentally verified that, effect is notable, safety good, can effectively treat atoipc dermatitis, treat skin erythema, edema that dermatitis causes, be that one can effectively treat dermopathic effective Traditional Chinese medicinal prescription.

These are only presently preferred embodiments of the present invention, not in order to limit the present invention, all within the spirit and principles in the present invention, any modification, equivalent substitution and improvement etc. made, should be included within the scope of the present invention.

Claims (2)

1. treat dermopathic prescription for one kind, it is characterised in that: it is made up of the raw material of following weight proportioning:

Radix Tripterygii Wilfordii 20-25, Rhizoma Picrorhizae 20-24, Semen Arecae 10-12, Radix Paeoniae Alba 10-12, Radix Angelicae Sinensis 8-10, Herba Cayatiae Japonicae 15-20, Radix et Caulis Opuntiae Dillenii 20-24, Cortex Dictamni 20-24, Herba Schizonepetae 10-12, Radix Saposhnikoviae 10-12, Radix Paeoniae Rubra 8-10, Radix Gentianae Grass 20-24, Radix Sophorae Flavescentis 10-12, Cortex Phellodendri 15-20, non-irrigated red lotus 15-20, Radix Rehmanniae 15-20, Radix Arnebiae (Radix Lithospermi) 10-12, Herba Senecionis Scandentis 10-12, Camphora 15-20, Radix Semiaquilegiae 15-20, Flos Lonicerae 10-12, Radix Tinosporae 15-20, Calyx seu Fructus physalis 15-20, Radix Sophorae Tonkinensis 15-20, Cortex Fraxini 15-20, Radix Pulsatillae 15-20, Radix Ampelopsis 10-12, Pseudobulbus Cremastrae Seu Pleiones 10-12, Herba Orostachyos 10-12, Borneolum Syntheticum 5-10.

One the most according to claim 1 treats dermopathic prescription, it is characterised in that: by following heavy The raw material of amount proportioning is made:

Radix Tripterygii Wilfordii 24, Rhizoma Picrorhizae 22, Semen Arecae 11, the Radix Paeoniae Alba 11, Radix Angelicae Sinensis 8, Herba Cayatiae Japonicae 17, Radix et Caulis Opuntiae Dillenii 22, Cortex Dictamni 22, Herba Schizonepetae 10, Radix Saposhnikoviae 11, Radix Paeoniae Rubra 9, Radix Gentianae 24, Radix Sophorae Flavescentis 11, Cortex Phellodendri 18, non-irrigated red lotus 19, Radix Rehmanniae 18, Radix Arnebiae (Radix Lithospermi) 11, Herba Senecionis Scandentis 12, Camphora 17, Radix Semiaquilegiae 16, Flos Lonicerae 10, Radix Tinosporae 18, Calyx seu Fructus physalis 17, Radix Sophorae Tonkinensis 18, Cortex Fraxini 17, the Radix Pulsatillae 17, Radix Ampelopsis 11, Pseudobulbus Cremastrae Seu Pleiones 11, Herba Orostachyos 12, Borneolum Syntheticum 8.