CN105963528A - ASD (atrial septal defect) postoperation traditional Chinese medicine and preparation method thereof - Google Patents

Abstract

The invention provides an ASD (atrial septal defect) postoperation traditional Chinese medicine and a preparation method thereof. Raw materials of the traditional Chinese medicine include: tea tree root, flower of Japanese glorybower, herba Salvia cavaleriei, Chaenomeles speciosa, chicory, limonium bicolor, mandarin pip, chinese wampee seed, Himalayan Eriosema, Champion Bauhinia seed, Chinese Osbeckia herb, Alectoria asiatica Du Rietz, Russian olive, Aeschynanthus acuminatus Wall., fruit of purpleflower holly, streptopus simplex, Polyalthia nemoralis, gymnadenia conopsea, root of burmann cinnamon, herba Loureiro Clematis, and herba michel galingale. The ASD postoperation traditional Chinese medicine has the beneficial effects: the postoperation traditional Chinese medicine is matched with an ASD operation for use, can effectively improve the cure rate and the total effective rate, and neither toxic and side effects nor adverse reactions appear.

Description

A kind of postoperative Chinese medicine of atrial septal defect and preparation method thereof

Technical field

The present invention relates to, containing the medicinal preparation deriving from plant, animal or mineral component, particularly relate to A kind of postoperative Chinese medicine of atrial septal defect and preparation method thereof.

Background technology

Atrial septal defect refers to that primitive atrium is spaced in occurring, occurring exception, the left and right heart when absorbing and merge Still remain the foramen primum of patent between room, cause the shunting of face, room blood flow.Room lacks can be with individualism, also Can exist with other cardiovascular malformations.Room lacks point foramen primum room and lacks scarce with secondary openings room, and commonly called room lacks I.e. refer to that secondary openings room lacks.Atrial septal defect is common congenital heart disease in children's period, the morbidity of this disease Rate is about the l/1500 of life birth baby, accounts for the 5%～10% of congenital heart disease sum, is interatrial septum In embryo development procedure caused by dysplasia.Occurring according to embryo, atrial septal defect can be divided into inhomogeneity Type, most commonly seen with ostium secundum defect clinically.Women is more common, and gender's ratio is 1:(2～3).

The symptom of primary disease and PD depend on defect size, and defect I asymptomatic long-term, defect is big Then symptom occurs early, and progressively develops into pulmonary hypertension.Diagnose the suitable early operation of clear and definite person, typically at school age Front operation is preferred.Room lacks greatly, shunting is big or heart failure person to perform the operation in advance.But severe pulmonary hypertension companion's dextrad is left Shunting, person is not suitable for performing an operation to occur cyanosis when calming down.Primary disease operative effect is definite, and operative mortality is relatively Low, postoperative can recover normal cardiac function completely.But companion's pulmonary hypertension person's operative mortality is high, and post-operative recovery is slow, Indivedual severe pulmonary hypertension persons lose the chance of operation, therefore answer early operation.Postoperative anti symptom treatment, prevention sense Dye, heart tonifying diuresis etc. is treated most important for the rehabilitation of infant with nursing.

Summary of the invention

The technical problem to be solved is, it is provided that a kind of postoperative Chinese medicine of atrial septal defect and Preparation method, this Chinese medicine can improve the therapeutic effect of atrial septal defect art, have no side effect.

In order to solve above-mentioned technical problem, the invention provides a kind of postoperative Chinese medicine of atrial septal defect, its Raw medicinal material includes: Radix Camelliae sinensis, Flos clerodendri japonici, Herba Salviae Cavaleriei, Caulis et folium stauntoniae, Herba Cichorii, Herba Limoii Bicoloris, Citrus chachiensis Hort. Core, Semen clausenae lansii, Eriosema himalaicum Ohashi, Semen Bauhiniae championii, Herba Osbeckiae, Alectoria asiatica Du Rietz, Fructus Elaeagni Angustifoliae, Shi Rong, Fructus Ilicis Purpureae, Streptopus simplex D. Don, Polyalthia nemoralis A. D C., Rhizoma Gymnadeniae, Radix Cinnamomi Burmanni, Herba Clematidis loureirianae and Cyperus michelianus(L.) Link (Herba Cyperi Micheliani).

Wherein, in described Chinese medicine, the ratio of weight and number of each raw medicinal material can be preferably as follows: Radix Camelliae sinensis 20～ 30 parts, Flos clerodendri japonici 15～25 parts, Herba Salviae Cavaleriei 10～20 parts, Caulis et folium stauntoniae 25～35 parts, Herba Cichorii 20～ 30 parts, Herba Limoii Bicoloris 25～40 parts, Citrus chachiensis Hort. (C．Suavissima Tanaka) 15～25 parts, Semen clausenae lansii 10～20 parts, continuous three 7 25～35 parts, Semen Bauhiniae championii 15～25 parts, Herba Osbeckiae 10～20 parts, Alectoria asiatica Du Rietz 25～35 parts, Fructus Elaeagni Angustifoliae 5～15 parts, Shi Rong 20～30 parts, Fructus Ilicis Purpureae 15～25 parts, Streptopus simplex D. Don 10～20 parts, casting skin Root 25～35 parts, Rhizoma Gymnadeniae 20～30 parts, Radix Cinnamomi Burmanni 25～40 parts, Herba Clematidis loureirianae 10～20 parts and Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 25～35 parts.

Wherein, in described Chinese medicine, the ratio of weight and number of each raw medicinal material can also be preferably as follows: Radix Camelliae sinensis 25～30 parts, Flos clerodendri japonici 15～20 parts, Herba Salviae Cavaleriei 10～15 parts, Caulis et folium stauntoniae 30～35 parts, Herba Cichorii 20～25 parts, Herba Limoii Bicoloris 30～35 parts, Citrus chachiensis Hort. (C．Suavissima Tanaka) 15～20 parts, Semen clausenae lansii 10～15 parts, Eriosema himalaicum Ohashi 25～30 parts, Semen Bauhiniae championii 15～20 parts, Herba Osbeckiae 10～15 parts, Alectoria asiatica Du Rietz 30～35 Part, Fructus Elaeagni Angustifoliae 5～10 parts, Shi Rong 25～30 parts, Fructus Ilicis Purpureae 20～25 parts, Streptopus simplex D. Don 15～20 parts, Polyalthia nemoralis A. D C. 30～35 parts, Rhizoma Gymnadeniae 20～25 parts, Radix Cinnamomi Burmanni 30～35 parts, Herba Clematidis loureirianae 10～15 Part and Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 25～30 parts.

Wherein, in described Chinese medicine, the ratio of weight and number of each raw medicinal material can be preferably as follows again: Radix Camelliae sinensis 26 Part, Flos clerodendri japonici 19 parts, Herba Salviae Cavaleriei 12 parts, Caulis et folium stauntoniae 35 parts, Herba Cichorii 21 parts, Herba Limoii Bicoloris 35 Part, Citrus chachiensis Hort. (C．Suavissima Tanaka) 17 parts, Semen clausenae lansii 15 parts, Eriosema himalaicum Ohashi 27 parts, Semen Bauhiniae championii 17 parts, Herba Osbeckiae 14 Part, Alectoria asiatica Du Rietz 32 parts, 9 parts of Fructus Elaeagni Angustifoliae, Shi Rong 27 parts, Fructus Ilicis Purpureae 25 parts, Streptopus simplex D. Don 16 parts is black Dermatome 35 parts, Rhizoma Gymnadeniae 21 parts, Radix Cinnamomi Burmanni 35 parts, Herba Clematidis loureirianae 15 parts and Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 26 parts.

Wherein, in described Chinese medicine, the ratio of weight and number of each raw medicinal material can be preferably as follows again: Radix Camelliae sinensis 29 Part, Flos clerodendri japonici 17 parts, Herba Salviae Cavaleriei 15 parts, Caulis et folium stauntoniae 32 parts, Herba Cichorii 25 parts, Herba Limoii Bicoloris 31 Part, Citrus chachiensis Hort. (C．Suavissima Tanaka) 18 parts, Semen clausenae lansii 12 parts, Eriosema himalaicum Ohashi 29 parts, Semen Bauhiniae championii 18 parts, Herba Osbeckiae 12 Part, Alectoria asiatica Du Rietz 35 parts, 7 parts of Fructus Elaeagni Angustifoliae, Shi Rong 29 parts, Fructus Ilicis Purpureae 21 parts, Streptopus simplex D. Don 19 parts is black Dermatome 32 parts, Rhizoma Gymnadeniae 25 parts, Radix Cinnamomi Burmanni 31 parts, Herba Clematidis loureirianae 12 parts and Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 28 parts.

Present invention also offers the preparation method of above-mentioned Chinese medicine, when the dosage form of described Chinese medicine is tablet, its system Preparation Method comprises the following steps:

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, add relative to mixture quality 2～ The determining alcohol of 4 times is the ethanol of 85～95%, is heated to reflux 1～3 hour, extracts, and filters acquisition first Extracting solution；Filter obtain medicinal residues add relative to the determining alcohol of described medicinal residues quality 1～2 times be 85～ The ethanol of 95%, is heated to reflux 1～3 hour, extracts, and filters and obtains the second extracting solution；Extract first Liquid and the second extracting solution merge, and concentrating under reduced pressure removes alcohol solvent, are dried, it is thus achieved that dry cream；

Second step, is placed in super micron mill pulverizing 1～2 hour by the dry cream that the first step obtains, and pulverizes, Sieve, it is thus achieved that 300 mesh～the micropowders of 400 mesh；

3rd step, the micropowders obtained by second step, add relative to its quality 0.1～0.3 times is micro- Crystalline cellulose, 0.05～0.15 times of lactose, starch of 0.1～0.3 times, sieve, mix homogeneously, pelletizes, It is dried, adds relative to micropowders quality 0.005～0.05 times of magnesium stearate, granulate, tabletting, system Become.

Present invention also offers the preparation method of above-mentioned Chinese medicine, when the dosage form of described Chinese medicine is capsule, its Preparation method comprises the following steps:

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, add relative to mixture quality 2～ The determining alcohol of 4 times is the ethanol of 85～95%, is heated to reflux 1～3 hour, extracts, and filters acquisition first Extracting solution；Filter obtain medicinal residues add relative to the determining alcohol of described medicinal residues quality 1～2 times be 85～ The ethanol of 95%, is heated to reflux 1～3 hour, extracts, and filters and obtains the second extracting solution；Extract first Liquid and the second extracting solution merge, and concentrating under reduced pressure removes alcohol solvent, are dried, it is thus achieved that dry cream；

Second step, is placed in super micron mill pulverizing 1～2 hour by the dry cream that the first step obtains, and pulverizes, Sieve, it is thus achieved that 300 mesh～the micropowders of 400 mesh；

3rd step, is sequentially added into Pulvis Talci, magnesium stearate in the micropowders that second step obtains, carries out Mixing processes, and obtains capsule 's content；Described micropowders, magnesium stearate and talcous weight ratio are 100: 0.15～0.5:0.15～0.5, described capsule 's content is loaded in capsule housing, obtains capsule Agent finished product.

Beneficial effects of the present invention: Chinese medicine of the present invention coordinates atrial septal defect art to use, it is possible to is effectively improved and controls More rate and total effective rate, have no side effect and untoward reaction.

Detailed description of the invention

The invention provides a kind of postoperative Chinese medicine of atrial septal defect, its raw medicinal material includes: Radix Camelliae sinensis, Flos clerodendri japonici, Herba Salviae Cavaleriei, Caulis et folium stauntoniae, Herba Cichorii, Herba Limoii Bicoloris, Citrus chachiensis Hort. (C．Suavissima Tanaka), Semen clausenae lansii, Eriosema himalaicum Ohashi, Semen Bauhiniae championii, Herba Osbeckiae, Alectoria asiatica Du Rietz, Fructus Elaeagni Angustifoliae, Shi Rong, Fructus Ilicis Purpureae, Herba Clematidis loureirianae and Cyperus michelianus(L.) Link (Herba Cyperi Micheliani).

In described Chinese medicine, the pharmacology of each raw medicinal material is as follows:

Flos clerodendri japonici: [another name] Flos paulowniae, loyal Flos paulowniae, close bag flower, dragon wears flower, fragrant small cup flower, Flos Ixorae Chinensis (Cacumen et Folium Clerodendri paniculati), Basilima sorbifolia, Caulis Akebiae lotus.[source] medical material Ji Yuan: for the flower of Verbenaceae paulownia.[nature and flavor] Sweet；Flat；[return through] spleen channel.[function cures mainly] calms the nerves；Hemostasis.Main palpitation and insomnia；Bleeding hemorrhoids. [each discussion] " Traditional Chinese Medicine in Sichuan will ": enrich blood, controls band disease, hemorrhoid, hernia, insomnia.[extracts] " China's book on Chinese herbal medicine "

Herba Salviae Cavaleriei: [another name] Radix ceratostigmatis willemottiani.[source] medical material Ji Yuan: for Maguireothamnus speciosus Guangzhou serpentaria The rhizome of grass.[nature and flavor] are bitter；Cold.[function cures mainly] clearing and antitussive；Tranquillizing and allaying excitement；Reducing swelling and alleviating pain. Main epersalgia cough；Cholera is vomited and diarrhoea；Neurasthenia；Menoxenia；Traumatic injury.[extracts] " China Book on Chinese herbal medicine "

Caulis et folium stauntoniae: move in [another name] Radix seu Herba Tetrastigmatis Hypoglauci, Wu Teng, August, Radix Stauntoniae chinensis, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), schefflera arboricola, Fructus Fici Pumilae.[source] medical material Ji Yuan: for plants of Lardizabalaceae Caulis et folium stauntoniae root, rhizome and stem and leaf.[nature and flavor] Sweet；Warm in nature.[return through] heart；Kidney channel.[function cures mainly] dispels the wind and network；Promoting blood circulation and stopping pain；Diuresis disappears Swollen.Main air pain of dampness syndrome；The pain of stomach, intestinal and biliary diseases；Trigeminal neuralgia；Traumatic injury；Bitterly Warp；Dysuria；Edema.[each discussion] 1. " pharmacologys of traditional Chinese medicines ": for heart tonifying, diuretic. 2. " GUIHAIA register ": rattan, pain relieving；Rattan and root, diuresis.[extracts] " China's book on Chinese herbal medicine "

Herba Cichorii: [source] is the aerial parts of feverfew saussurea intybus and Herba Cichorii.[nature and flavor] micro-hardship, Salty, cool.[function cures mainly] liver heat removing function of gallbladder promoting, invigorating the stomach and promoting digestion, inducing diuresis to remove edema.For jaundice due to damp-heat, stomach Lack of appetite bitterly, edema oliguria.[extracts] " Chinese Pharmacopoeia "

Herba Limoii Bicoloris: [another name] Scorpio Herba Astragali Sinici, wild spinach, burn eyebrow Artemisia, Herba Limonii Gmelinii, Radix limonii sinensis, Herba Chenopodii Hybridi, Limonium spp..[source] medical material Ji Yuan: for the root or complete of Plumbaginaceae plant Herba Limoii Bicoloris Grass.[nature and flavor] are sweet；Micro-hardship；Slightly warm in nature；[return through] spleen；Liver；Bladder warp.[function cures mainly] Replenishing QI and blood；Dissipating blood stasis stops blooding.Main the most weak；Gastric abscess；Dyspepsia；Menoxenia, metrorrhagia； Leukorrhagia；Hematuria；Hemorrhoidal bleeding.[each discussion] 1. " Gansu Chinese herbal medicine handbook ": blood yiqi, invigorates blood circulation Regulating menstruation.After curing the disease weak, dyspepsia, menoxenia.[extracts] " China's book on Chinese herbal medicine "

Citrus chachiensis Hort. (C．Suavissima Tanaka): [source] medical material Ji Yuan: for the seed of the multiple Citrus chachiensis Hort. classes such as rutaceae Citrus reticulata Blanco cv. Chachiensis.[property Taste] bitter；Pungent；Temperature；[return through] heart；Liver.[function cures mainly] the kidney warming pain relieving；Promoting QI to circulate and dispersing the agglomeration of the pathogens.Main Lumbago；Colicky pain of bladder；Inguinal hernia；The testis swelling and hanging down of either of the testes swells and ache.[extracts] " China's book on Chinese herbal medicine "

Semen clausenae lansii: [another name] Clausena lansium (Lour.) Skeels core.[source] medical material Ji Yuan: for rutaceae Clausena lansium (Lour.) Skeels Seed.[nature and flavor] acrid in the mouth；Micro-hardship；Tepor；[return through] lung；Stomach；Liver Channel.[function cures mainly] Promoting the circulation of QI to relieve pain；Detoxicating and resolving stagnation of pathogens.Staple food indigestion pain；Stagnation of QI epigastric pain；Colic；Painful and swollen testis；Dysmenorrhea； Children's's head sore；Centipete bite.[each discussion] " Guangxi Chinese medicinal herbal ": circulation of qi promoting, disappears stagnant, eliminating stagnation. Control dyspepsia stomachache, painful and swollen testis.[extracts] " China's book on Chinese herbal medicine "

Eriosema himalaicum Ohashi: [another name] grass young potato, mountain Fructus Tsaoko, Gallus jabouillei head, mountain Fructus Tsaoko, Ipomoea hungaiensis Lingelsh. Et Borza., Herba Violae mundae. [source] medical material Ji Yuan: for the tuber of leguminous plant Eriosema himalaicum Ohashi.[nature and flavor] are sweet；Bitter；Flat；[return Warp] spleen；Stomach；Liver Channel.[function cures mainly] spleen invigorating removing food stagnancy；Promoting the circulation of QI to relieve pain；Removing toxic substances and promoting subsidence of swelling.Main infantile malnutrition； Dyspepsia；Epigastric pain；Diarrhoea；Dysentery；Painful and swollen testis；Shen gas；Throat pain；Traumatic injury； Sore.[each discussion] 1. " Kunming conventional medical herbs among the people ": analgesia, pulls out sore.[extracts] " in China's book on Chinese herbal medicine "

Semen Bauhiniae championii: [source] medical material Ji Yuan: for the seed of leguminous plant Caulis Bauhihiae Championii.[nature and flavor] are bitter Pungent；Temperature；[return through] liver；Stomach warp.[function cures mainly] promoting the circulation of QI to relieve pain；Blood circulation promoting and blood stasis dispelling.Main side of body rib is swollen Bitterly, gastric abscess, traumatic injury.[each discussion] 1. " south of the Five Ridges gather medicinal herbs record ": only pain due to disorder of QI, reason traumatic injury wound, Eliminating blood stasis to promote regeneration of blood.[extracts] " China's book on Chinese herbal medicine "

Herba Osbeckiae: [another name] Zijin kind, sky hang perfume (or spice), cup of looking up to heaven, Cortex Argyreiae Seguinii Radicis, gold pomegranate, Zijin clock, Gold incense burner, clock of looking up to heaven.[source] medical material Ji Yuan: for herb or the root of Melastomateae plants Radix Osbeckiae Crinitae. [nature and flavor] acrid in the mouth；Light；Property flat；[return through] returns lung；Spleen；Liver；Large intestine channel.[function cures mainly] Reduce phlegm dampness removing；Hemostasis by removing blood stasis；Removing toxic substances and promoting subsidence of swelling.Main cough；Asthma；Dysentery；Have loose bowels；Spit blood；Spitting of blood； Have blood in stool；Amenorrhea；Infantile malnutrition；Rheumatic ostalgia；Traumatic injury.[each discussion] 1. " Nanning City's medicine will ": Eliminating blood stasis to promote regeneration of blood, pain relieving restrains.Control interior external haemorrhage, infantile malnutrition, ulcerative gingivitis, toothache, cough.2. " south of the Five Ridges grass Medicine will ": removing dampness disappears stagnant, antipyretic-antalgic.[extracts] " China's book on Chinese herbal medicine "

Alectoria asiatica Du Rietz: [another name] black silk grass, Rhizoma Tupistrae Chinensis, black silk ribbon.[source] medical material Ji Yuan: for pine Trailing plants section plant Asia tree sends out, double-colored tree sends out, set send out, the thallus of ditch tree.[nature and flavor] are light；Property flat； [return through] liver；Kidney；Bladder warp.[function cures mainly] nourishing the kidney and liver；Arresting seminal emission hidroschesis；Inducing diuresis to remove edema； Removing dampness sore.Main kidney deficiency and bodily weakness；The vertigo；Cardiopalmus；Seminal emission；Night sweat；Stranguria；Edema；Yellow fluid Skin ulcer.[extracts] " China's book on Chinese herbal medicine "

Fructus Elaeagni Angustifoliae: [another name] four taste fruit, Semen Phaseoli, gigue reach.[source] medical material Ji Yuan: for Fructus Elaeagni Section's plant Fructus Elaeagni Angustifoliae, east Fructus Elaeagni Angustifoliae and the mature fruit of point fruit Fructus Elaeagni Angustifoliae.[nature and flavor] sour in the mouth；Micro-sweet；Cool in nature； [return through] lung；Liver；Spleen；Stomach；Kidney channel.[function cures mainly] liver-nourishing kidney-boosting；Spleen invigorating regulating menstruation.Main liver Empty dizzy；Lumbago due to renal deficiency；Insufficiency of the spleen diarrhoea；Dyspepsia；Leukorrhagia；Menoxenia.[each discussion] " Chinese Herbal Medicine in Xinjiang handbook ": strong, calm, controlling nocturnal emission with astringent drugs, stomach invigorating, antidiarrheal, regulating menstruation, diuresis.Control stomach Bitterly, diarrhoea, physical weakness, cough due to lung-heat.[extracts] " China's book on Chinese herbal medicine "

Shi Rong: [another name] great Ye banyan rattan, cliff wind, Fici hispidae, the most leeward, Shi Nanfeng.[source] Medical material Ji Yuan: for the herb of Gesneriaceae awns hair lettuce tongue.[nature and flavor] sweet in the mouth；Property flat.[function Cure mainly] mind calming；Nourishing the liver；Cough-relieving；Pain relieving.Main neurasthenia, chronic hepatitis；Cough；Rheumatic ostalgia； Traumatic injury.[extracts] " China's book on Chinese herbal medicine "

Fructus Ilicis Purpureae: [another name] Ilicis Purpureae is real, freeze blue or green tree.[source] medical material Ji Yuan: plant for Aquifoliaceae The fruit of thing Ilicis Purpureae.[nature and flavor] are sweet；Bitter；Cool；[return through] liver；Kidney channel.[function cures mainly] mends Liver and kidney；Curing rheumatism；Arresting bleeding and healing up ulcer.Main early whitening of beard and hair；Wind shows arthralgia pain；Digestive ulcerative bleeding；Hemorrhoid； Ulcer being unable to heal.[each discussion] " book on Chinese herbal medicine is looked for the truth ": the strong muscle of tonifying liver, reinforcing the kidney to strengthen the bone.[extracts] " in China's book on Chinese herbal medicine "

Streptopus simplex D. Don: [another name] Radix Streptopi Simplicis, female's short, bristly hair or beard.[source] medical material Ji Yuan: for liliaceous plant axil Flower turns round the root of handle flower.[nature and flavor] are sweet；It is slightly cold.[function cures mainly] clearing away lung-heat to relieve cough；Invigorating the spleen and regulating the stomach.Main Cough due to lung-heat；Deficiency of YIN chronic cough；Few food of incoordination between the spleen and stomach；Nausea.[extracts] " China's book on Chinese herbal medicine "

Polyalthia nemoralis A. D C.: [another name] falls bank potato.[source] medical material Ji Yuan: dark for annonaceae plant Lingshui The root of sieve.[nature and flavor] are sweet；Flat；[return through] spleen；Stomach；Kidney channel.[function cures mainly] strengthens the spleen and stomach； Nourishing kidney controlling nocturnal emission with astringent drugs；Main chronic gastritis；Taste lose；Inappetence；Myasthenia of limbs；Seminal emission.[extracts] " China's book on Chinese herbal medicine " " Chinese medicine voluminous dictionary "

Rhizoma Gymnadeniae: [another name] hides Radix Notoginseng, Fructus Citri Sarcodactylis ginseng, palm ginseng, hands ginseng, negative and positive ginseng.[source] Medical material Ji Yuan: for orchid Rhizoma Gymnadeniae or the tuber of gymnadenia crassinervis Finet.[nature and flavor] are sweet；Flat；[return through] Lung；Spleen；Stomach warp.[function cures mainly] relieving cough and asthma；Yishen Jianpi；Regulate the flow of vital energy and blood；Pain relieving.Main lung Empty cough with asthma；Asthenia is become thin；Neurasthenia；Suffer from a deficiency of the kidney lassitude loin and legs；Sexual impotence；Spermatorrhea；Frequent micturition；Chronic Liver Scorching；Chronic diarrhea；Lose blood；Leukorrhagia；Breast is few；Traumatic injury.[each discussion] " Shaanxi Chinese herbal medicine ": Strengthening by means of tonics, spleen reinforcing lung moistening, calm the nerves relieving convulsion, QI invigorating pain relieving.Control physical weakness, neurasthenia, impairment caused by overstrain, Cough, asthma.[extracts] " China's book on Chinese herbal medicine "

Radix Cinnamomi Burmanni: [source] medical material Ji Yuan: the root fragrant for canella the moon or root bark.[nature and flavor] are pungent； Micro-sweet；Warm in nature；[return through] stomach warp.[function cures mainly] warming middle-JIAO to promote flow of QI pain relieving.Cure mainly the cold pain of gastral cavilty； The stagnation of QI is pained, watery diarrhea.[each discussion] " south of the Five Ridges gather medicinal herbs record ": decoction, controls pained, pain due to disorder of QI.[pluck Record] " China's book on Chinese herbal medicine " " Chinese medicine voluminous dictionary "

Herba Clematidis loureirianae: [another name] wild Caulis Akebiae, Caulis Clematidis Chrysocomae, ferrum foot Wheeling, RADIX ANEMONAE.[source] Medical material Ji Yuan: for rattan or the root of ranunculaceae plant gold pig-iron line.[nature and flavor] sweet in the mouth；Light；Property flat； [return through] returns liver；Kidney；Bladder warp.[function cures mainly] clearing away heat and promoting diuresis；Promoting blood circulation to restore menstrual flow；Expelling wind and removing dampness. Main dysuria；Edema；Damp-heat gonorrhoea；Rheumatic arthralgia；Traumatic injury；Inflammation on wind-fire；Eye red pain； Amenorrhea；Mange.[extracts] " China's book on Chinese herbal medicine "

Cyperus michelianus(L.) Link (Herba Cyperi Micheliani): [another name] attached heart grass.[source] medical material Ji Yuan: revolve squama dried tuber for sedge Herb.[nature and flavor] acrid in the mouth；Light；Property flat；[return through] liver；Spleen channel.[function cures mainly] circulation of qi promoting Nourish blood；Regulating menstruation.Main menoxenia；Dysmenorrhea.[each discussion] " classifying herbal ": nourishing blood for regulating menstruation. [extracts] " China's book on Chinese herbal medicine "

Wherein, in described Chinese medicine, the ratio of weight and number of each raw medicinal material can be preferably as follows: Radix Camelliae sinensis 20～ 30 parts, Flos clerodendri japonici 15～25 parts, Herba Salviae Cavaleriei 10～20 parts, Caulis et folium stauntoniae 25～35 parts, Herba Cichorii 20～ 30 parts, Herba Limoii Bicoloris 25～40 parts, Citrus chachiensis Hort. (C．Suavissima Tanaka) 15～25 parts, Semen clausenae lansii 10～20 parts, continuous three 7 25～35 parts, Semen Bauhiniae championii 15～25 parts, Herba Osbeckiae 10～20 parts, Alectoria asiatica Du Rietz 25～35 parts, Fructus Elaeagni Angustifoliae 5～15 parts, Shi Rong 20～30 parts, Fructus Ilicis Purpureae 15～25 parts, Streptopus simplex D. Don 10～20 parts, casting skin Root 25～35 parts, Rhizoma Gymnadeniae 20～30 parts, Radix Cinnamomi Burmanni 25～40 parts, Herba Clematidis loureirianae 10～20 parts and Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 25～35 parts.

Wherein, in described Chinese medicine, the ratio of weight and number of each raw medicinal material can also be preferably as follows: Radix Camelliae sinensis 25～30 parts, Flos clerodendri japonici 15～20 parts, Herba Salviae Cavaleriei 10～15 parts, Caulis et folium stauntoniae 30～35 parts, Herba Cichorii 20～25 parts, Herba Limoii Bicoloris 30～35 parts, Citrus chachiensis Hort. (C．Suavissima Tanaka) 15～20 parts, Semen clausenae lansii 10～15 parts, Eriosema himalaicum Ohashi 25～30 parts, Semen Bauhiniae championii 15～20 parts, Herba Osbeckiae 10～15 parts, Alectoria asiatica Du Rietz 30～35 Part, Fructus Elaeagni Angustifoliae 5～10 parts, Shi Rong 25～30 parts, Fructus Ilicis Purpureae 20～25 parts, Streptopus simplex D. Don 15～20 parts, Polyalthia nemoralis A. D C. 30～35 parts, Rhizoma Gymnadeniae 20～25 parts, Radix Cinnamomi Burmanni 30～35 parts, Herba Clematidis loureirianae 10～15 Part and Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 25～30 parts.

Wherein, in described Chinese medicine, the ratio of weight and number of each raw medicinal material can be preferably as follows again: Radix Camelliae sinensis 26 Part, Flos clerodendri japonici 19 parts, Herba Salviae Cavaleriei 12 parts, Caulis et folium stauntoniae 35 parts, Herba Cichorii 21 parts, Herba Limoii Bicoloris 35 Part, Citrus chachiensis Hort. (C．Suavissima Tanaka) 17 parts, Semen clausenae lansii 15 parts, Eriosema himalaicum Ohashi 27 parts, Semen Bauhiniae championii 17 parts, Herba Osbeckiae 14 Part, Alectoria asiatica Du Rietz 32 parts, 9 parts of Fructus Elaeagni Angustifoliae, Shi Rong 27 parts, Fructus Ilicis Purpureae 25 parts, Streptopus simplex D. Don 16 parts is black Dermatome 35 parts, Rhizoma Gymnadeniae 21 parts, Radix Cinnamomi Burmanni 35 parts, Herba Clematidis loureirianae 15 parts and Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 26 parts.

Wherein, in described Chinese medicine, the ratio of weight and number of each raw medicinal material can be preferably as follows again: Radix Camelliae sinensis 29 Part, Flos clerodendri japonici 17 parts, Herba Salviae Cavaleriei 15 parts, Caulis et folium stauntoniae 32 parts, Herba Cichorii 25 parts, Herba Limoii Bicoloris 31 Part, Citrus chachiensis Hort. (C．Suavissima Tanaka) 18 parts, Semen clausenae lansii 12 parts, Eriosema himalaicum Ohashi 29 parts, Semen Bauhiniae championii 18 parts, Herba Osbeckiae 12 Part, Alectoria asiatica Du Rietz 35 parts, 7 parts of Fructus Elaeagni Angustifoliae, Shi Rong 29 parts, Fructus Ilicis Purpureae 21 parts, Streptopus simplex D. Don 19 parts is black Dermatome 32 parts, Rhizoma Gymnadeniae 25 parts, Radix Cinnamomi Burmanni 31 parts, Herba Clematidis loureirianae 12 parts and Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 28 parts.

Present invention also offers the preparation method of above-mentioned Chinese medicine, when the dosage form of described Chinese medicine is tablet, its system Preparation Method comprises the following steps:

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, add relative to mixture quality 2～ The determining alcohol of 4 times is the ethanol of 85～95%, is heated to reflux 1～3 hour, extracts, and filters acquisition first Extracting solution；Filter obtain medicinal residues add relative to the determining alcohol of described medicinal residues quality 1～2 times be 85～ The ethanol of 95%, is heated to reflux 1～3 hour, extracts, and filters and obtains the second extracting solution；Extract first Liquid and the second extracting solution merge, and concentrating under reduced pressure removes alcohol solvent, are dried, it is thus achieved that dry cream；

Second step, is placed in super micron mill pulverizing 1～2 hour by the dry cream that the first step obtains, and pulverizes, Sieve, it is thus achieved that 300 mesh～the micropowders of 400 mesh；

3rd step, the micropowders obtained by second step, add relative to its quality 0.1～0.3 times is micro- Crystalline cellulose, 0.05～0.15 times of lactose, starch of 0.1～0.3 times, sieve, mix homogeneously, pelletizes, It is dried, adds relative to micropowders quality 0.005～0.05 times of magnesium stearate, granulate, tabletting, system Become.

Present invention also offers the preparation method of above-mentioned Chinese medicine, when the dosage form of described Chinese medicine is capsule, its Preparation method comprises the following steps,

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, add relative to mixture quality 2～ The determining alcohol of 4 times is the ethanol of 85～95%, is heated to reflux 1～3 hour, extracts, and filters acquisition first Extracting solution；Filter obtain medicinal residues add relative to the determining alcohol of described medicinal residues quality 1～2 times be 85～ The ethanol of 95%, is heated to reflux 1～3 hour, extracts, and filters and obtains the second extracting solution；Extract first Liquid and the second extracting solution merge, and concentrating under reduced pressure removes alcohol solvent, are dried, it is thus achieved that dry cream；

Second step, is placed in super micron mill pulverizing 1～2 hour by the dry cream that the first step obtains, and pulverizes, Sieve, it is thus achieved that 300 mesh～the micropowders of 400 mesh；

3rd step, is sequentially added into Pulvis Talci, magnesium stearate in the micropowders that second step obtains, carries out Mixing processes, and obtains capsule 's content；Described micropowders, magnesium stearate and talcous weight ratio are 100: 0.15～0.5:0.15～0.5, described capsule 's content is loaded in capsule housing, obtains capsule Agent finished product.

Hereinafter use embodiment to describe embodiments of the present invention in detail, fully understand that the present invention is such as whereby What application technology means solves technical problem, reaches technique effect and implements according to this.

Embodiment 1: tablet

Take Radix Camelliae sinensis 260g, Flos clerodendri japonici 190g, Herba Salviae Cavaleriei 120g, Caulis et folium stauntoniae 350g, Herba Cichorii 210g, Herba Limoii Bicoloris 350g, Citrus chachiensis Hort. (C．Suavissima Tanaka) 170g, Semen clausenae lansii 150g, Eriosema himalaicum Ohashi 270g, Semen Bauhiniae championii 170g, Herba Osbeckiae 140g, Alectoria asiatica Du Rietz 320g, Fructus Elaeagni Angustifoliae 90g, Shi Rong 270g, Fructus Ilicis Purpureae 250g, Streptopus simplex D. Don 160g, Polyalthia nemoralis A. D C. 350g, Rhizoma Gymnadeniae 210g, Radix Cinnamomi Burmanni 350g, Herba Clematidis loureirianae 150g and Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 260g.

Prepare according to the following steps:

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, adds relative to mixture quality 4 The ethanol that determining alcohol is 95% again, is heated to reflux 3 hours, extracts, and filters and obtains the first extracting solution； Filter the medicinal residues obtained and add the ethanol that determining alcohol is 85% relative to described medicinal residues quality 2 times, add Hot reflux 3 hours, extracts, and filters and obtains the second extracting solution；First extracting solution and the second extracting solution are closed And, concentrating under reduced pressure removes alcohol solvent, is dried, it is thus achieved that dry cream；

Second step, is placed in super micron mill pulverizing 2 hours by the dry cream that the first step obtains, and pulverizes, Sieve, it is thus achieved that the micropowders of 400 mesh；

3rd step, the micropowders that second step is obtained, add fine relative to the crystallite of its quality 0.28 times Dimension element, 0.44 times of lactose, starch of 0.26 times, sieve, and mix homogeneously is pelletized, and is dried, and adds phase For 0.035 times of magnesium stearate of micropowders quality, granulate, tabletting, make.

Embodiment 2: capsule

Take Radix Camelliae sinensis 290g, Flos clerodendri japonici 170g, Herba Salviae Cavaleriei 150g, Caulis et folium stauntoniae 320g, Herba Cichorii 250g, Herba Limoii Bicoloris 310g, Citrus chachiensis Hort. (C．Suavissima Tanaka) 180g, Semen clausenae lansii 120g, Eriosema himalaicum Ohashi 290g, Semen Bauhiniae championii 180g, Herba Osbeckiae 120g, Alectoria asiatica Du Rietz 350g, Fructus Elaeagni Angustifoliae 70g, Shi Rong 290g, Fructus Ilicis Purpureae 210g, Streptopus simplex D. Don 190g, Polyalthia nemoralis A. D C. 320g, Rhizoma Gymnadeniae 250g, Radix Cinnamomi Burmanni 310g, Herba Clematidis loureirianae 120g and Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 280g.

Prepare according to the following steps:

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, adds relative to mixture quality 4 The ethanol that determining alcohol is 95% again, is heated to reflux 3 hours, extracts, and filters and obtains the first extracting solution； Filter the medicinal residues obtained and add the ethanol that determining alcohol is 95% relative to described medicinal residues quality 2 times, add Hot reflux 3 hours, extracts, and filters and obtains the second extracting solution；First extracting solution and the second extracting solution are closed And, concentrating under reduced pressure removes alcohol solvent, is dried, it is thus achieved that dry cream；

Second step, is placed in super micron mill pulverizing 2 hours by the dry cream that the first step obtains, and pulverizes, Sieve, it is thus achieved that the micropowders of 400 mesh；

3rd step, is sequentially added into Pulvis Talci, magnesium stearate in the micropowders that second step obtains, carries out Mixing processes, and obtains capsule 's content；Described micropowders, magnesium stearate and talcous weight ratio are 100: 0.45:0.25, described capsule 's content is loaded in capsule housing, obtains capsule finished product.

Toxicity test:

Acute toxicity testing: application mice 60, male and female half and half, body weight 20-32g, carries out acute poison Property test.Mice is randomly divided into two groups, i.e. matched group and administration group, fasting 12 hours before experiment, incite somebody to action this The Chinese medicinal tablet of inventive embodiment 1 preparation is dissolved in water, and (concentration is 8.85g crude drug/ml, the highest Concentration) gavage, gavage volume is 5ml/kg (i.e. unit dosage form is 44.25 crude drugs/kg), right Give normal saline according to group, within one day, be administered 2 times, delivery time 6 hours, after administration continuously Observe 14 days, and record mice toxic reaction and death toll.Test result indicate that: with matched group ratio Relatively, after administration, mice has no notable difference, experiment Continuous Observation 14 days, mouse systemic situation, diet, Drinking-water, body weight increase the most normal.Tablet LD50 > 44.25 crude drugs/the kg of the Mouse oral gavage present invention, Every day, maximum dosage-feeding was 88.5 crude drugs/kg/ day.The Chinese medicine clinical application amount of the present invention be 8.2g crude drug/ Day/people, adult's body weight is in terms of 60KG, and average dosage is 0.137g crude drug/kg/ day.By weighing machine: The dosis tolerata of the Chinese medicine of mice (average weight is in terms of 26g) the oral administration gavage present invention as quantity 646 Times.Therefore the Chinese medicine acute toxicity of the present invention is extremely low, clinical drug safety.

Long term toxicity test: three groups of mices (often group 20) are pressed by Chinese medicine embodiment 1 tablet of the present invention 15.74,23.58 and 45.92g crude drugs/kg continuous use 15 weeks (1.0ml/100g body weight, every day 2 Secondary) and drug withdrawal 3 weeks after, result shows: Chinese medicine of the present invention is to the hair of mice, behavior, defecation, body The indexs such as weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat all have no significant effect, internal organs meat Eye does not find that difference change and histological indications show, after medication 15 weeks and drug withdrawal 3 weeks, and mice Each internal organs are all without substantially changing.Illustrate that Chinese medicine of the present invention is little, after drug withdrawal also to toxicity after mice long-term prescription There is no difference reaction, application safety.

Clinical data:

Case selection: 68 selected example patients are all from the patients with atrial septal defect that my institute accepts for medical treatment, divide at random It is two groups, treatment group 34 example, male 14 examples, female 20 example.Age 2～54 years old.Matched group 34 example, Man's 13 examples, female 21 example, age 2～52 years old.Two groups of patients are in sex, age and clinical symptoms etc. As data aspect compare and there was no significant difference, there is comparability.

Diagnostic criteria: 1, symptom: the little person of defect can be asymptomatic, defect big person shunt volume is big, right cardiac load Increase, may occur in which cardiopalmus, asthma, weak after activity, may occur in which pulmonary hypertension late period, cause dextrad left Shunting.Easily cause heart failure, be susceptible to suffer from pulmonary infection, affect growth promoter.2, sign: can intentionally expand on boundary Greatly, precordial prominence, heartbeat disperse, II systole can be heard in second and third intercostal of left border of sternum Noise, pulmonic second sound is hyperfunction and solid divides.The big person of M-mode echocardiography, owing to Tricuspid valve is relative Narrow, diastolic murmur can be heard below left border of sternum.3, x-ray inspection: have right atrium, right ventricle Expanding, pulmonary artery section substantially highlights, and hilar vascular shadows increases thick, and hilus pulumonis " dancing " can be had to levy, and lung field fills Blood, aortic arch reduces.4, electrocardiogram: RAD and incomplete right bundle-branch block, the right heart Hypertrophy, the case that the first hole is not rolled into a ball, common LAD and left ventricular hypertrophy.5, ultrasoundcardiogram: right Room, right ventricle increase, and Ad is less, and fan section ultrasound can directly display the position of atrial septal defect Put and size.Doppler color flow imaging can directly see the position of shunting, direction, can estimate shunting Size.6, cardiac catheterization: right room oxygen content is higher than superior and inferior vena cava average blood oxygen content, conduit May be by being entered left atrium by right room at defect.

Therapeutic Method:

Matched group: give routine operation treatment, punctures right lateral thigh vein under whole body or local anesthesia, gives Give heparin 100u/kg, complete right cardiac catheterization, through end-hole catheter, 0.035 × 260cm is replaced seal wire It is fed through left superior pulmonary vein, delivers to, in left room, withdraw from guiding steel wire, warp by ASD delivery sheath along seal wire TTE or transesophageal ultrasonography measure ASD size, select suitable stopper, are loaded on steel conveying, Send into along sheath pipe, under x-ray and ultrasonic monitoring, in left room, first open left room umbrella, pull back and make it be close to At atrial septal defect, " waist " is stuck in ASD completely, then withdraws delivery sheath, makes right atrium Opening, stopper position suitable is shown in row ultrasonic examination, and left to right shunt disappears, and checks after row distraction test Ultrasonic, if stopper is without displacement, rotate steel conveying counterclockwise, discharge stopper, exit conveyer device, Site of puncture hemostasis by compression, postoperative flat sleeping 1-2d, Low molecular heparin anticoagulant 24h, conventional application antibiotic 3d (preferably cephalo-type), oral aspirin 3 months, be grown up 5mg/kg d, child 3mg/kg d, Immediate postoperative, 1d, January, March, half a year check rabat, Color Sonography and electrocardiogram, observe lung blood and change Become and the shape and structure change etc. of stopper.

Treatment group: on the basis for the treatment of of control group, treatment group patient takes the embodiment of the present invention 1 simultaneously Tablet, each 3, three times a day.Chinese medicine 1 month is a course for the treatment of, treats 3 courses for the treatment of.

Curative effect judging standard: with reference to " clinical disease diagnosis and curative effect judging standard ".Cure: underwent operative Repairing or after intubation intervention method closure defect, without shunting and complication, symptom, sign disappear, heart merit Can recover normal.Take a turn for the better: symptom alleviates, and cardiac function makes moderate progress.Invalid: before and after treatment, symptom is without bright Aobvious alleviation or improvement, even deteriorate.

Therapeutic outcome: be shown in Table 1.

Two groups of Clinical efficacy comparisons (example) of table 13 months after operation

By table 1, relative to matched group, treatment group uses Chinese medicine of the present invention by postoperative adding, hence it is evident that Improve total effective rate and cure rate.

Untoward reaction: during two groups of patient treatments, all do not occur the hepatic and renal function injure relevant to medicine or Other untoward reaction.

Concrete case: high certain, female, 24 years old, occur climbing two to three floors without obvious inducement before about more than one month I.e. having obvious tachypnea, sense cardiopalmus to have palpitation after ladder, level walking is unrestricted, it is impossible to runs, can not put down night Lying, when turning round, tachypnea is obvious, can only left lateral position, start, without substantially cough, to generate heat without fear of cold, without robber Antiperspirant, without chest pain, sees a doctor to the court, and row chest film inspection shows a small amount of hydrothorax in left side, and Color Sonography shows: Atrial septal defect.Give the Closure of Atrial Septal Defect of matched group, postoperative Aspirin and the present invention The tablet of embodiment 1,3 months after operation is checked, and without shunting and complication, symptom, sign disappear, the heart Functional rehabilitation is normal, cures, and follows up a case by regular visits to postoperative 12 months without recurrence.

The above, be only presently preferred embodiments of the present invention, is not that the present invention makees other form Restriction, any those skilled in the art are changed possibly also with the technology contents of the disclosure above Or it is modified as the Equivalent embodiments of equivalent variations.But every without departing from technical solution of the present invention content, depend on Any simple modification, equivalent variations and remodeling above example made according to the technical spirit of the present invention, Still fall within the protection domain of technical solution of the present invention.

Claims (9)

1. the postoperative Chinese medicine of atrial septal defect, it is characterised in that each raw medicinal material bag in described Chinese medicine Include: Radix Camelliae sinensis, Flos clerodendri japonici, Herba Salviae Cavaleriei, Caulis et folium stauntoniae, Herba Cichorii, Herba Limoii Bicoloris, Citrus chachiensis Hort. (C．Suavissima Tanaka), Fructus clausenae lansii Core, Eriosema himalaicum Ohashi, Semen Bauhiniae championii, Herba Osbeckiae, Alectoria asiatica Du Rietz, Fructus Elaeagni Angustifoliae, Shi Rong, Fructus Ilicis Purpureae, Herba Clematidis loureirianae And Cyperus michelianus(L.) Link (Herba Cyperi Micheliani).

2. Chinese medicine as claimed in claim 1, it is characterised in that the weight of each raw medicinal material in described Chinese medicine Amount portion rate is as follows: Radix Camelliae sinensis 20～30 parts, Flos clerodendri japonici 15～25 parts, Herba Salviae Cavaleriei 10～20 parts, wild Fructus Chaenomelis 25～35 parts, Herba Cichorii 20～30 parts, Herba Limoii Bicoloris 25～40 parts, Citrus chachiensis Hort. (C．Suavissima Tanaka) 15～25 parts, Semen clausenae lansii 10～20 parts, Eriosema himalaicum Ohashi 25～35 parts, Semen Bauhiniae championii 15～25 parts, Herba Osbeckiae 10～ 20 parts, Alectoria asiatica Du Rietz 25～35 parts, Fructus Elaeagni Angustifoliae 5～15 parts, Shi Rong 20～30 parts, Fructus Ilicis Purpureae 15～25 Part, Streptopus simplex D. Don 10～20 parts, Polyalthia nemoralis A. D C. 25～35 parts, Rhizoma Gymnadeniae 20～30 parts, Radix Cinnamomi Burmanni 25～ 40 parts, Herba Clematidis loureirianae 10～20 parts and Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 25～35 parts.

3. Chinese medicine as claimed in claim 1 or 2, it is characterised in that each raw medicinal material in described Chinese medicine Ratio of weight and number as follows: Radix Camelliae sinensis 25～30 parts, Flos clerodendri japonici 15～20 parts, Herba Salviae Cavaleriei 10～15 Part, Caulis et folium stauntoniae 30～35 parts, Herba Cichorii 20～25 parts, Herba Limoii Bicoloris 30～35 parts, Citrus chachiensis Hort. (C．Suavissima Tanaka) 15～ 20 parts, Semen clausenae lansii 10～15 parts, Eriosema himalaicum Ohashi 25～30 parts, Semen Bauhiniae championii 15～20 parts, it is fragrant Stove 10～15 parts, Alectoria asiatica Du Rietz 30～35 parts, Fructus Elaeagni Angustifoliae 5～10 parts, Shi Rong 25～30 parts, Fructus Ilicis Purpureae 20～25 parts, Streptopus simplex D. Don 15～20 parts, Polyalthia nemoralis A. D C. 30～35 parts, Rhizoma Gymnadeniae 20～25 parts are cloudy fragrant Root 30～35 parts, Herba Clematidis loureirianae 10～15 parts and Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 25～30 parts.

4. the Chinese medicine as described in claims 1 to 3, it is characterised in that each raw medicinal material in described Chinese medicine Ratio of weight and number as follows: Radix Camelliae sinensis 26 parts, Flos clerodendri japonici 19 parts, Herba Salviae Cavaleriei 12 parts, Caulis et folium stauntoniae 35 Part, Herba Cichorii 21 parts, Herba Limoii Bicoloris 35 parts, Citrus chachiensis Hort. (C．Suavissima Tanaka) 17 parts, Semen clausenae lansii 15 parts, Eriosema himalaicum Ohashi 27 Part, Semen Bauhiniae championii 17 parts, Herba Osbeckiae 14 parts, Alectoria asiatica Du Rietz 32 parts, 9 parts of Fructus Elaeagni Angustifoliae, Shi Rong 27 parts, Fructus Ilicis Purpureae 25 parts, Streptopus simplex D. Don 16 parts, Polyalthia nemoralis A. D C. 35 parts, Rhizoma Gymnadeniae 21 parts, Radix Cinnamomi Burmanni 35 parts, gold Silk Caulis Akebiae 15 parts and Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 26 parts.

5. the Chinese medicine as described in Claims 1-4, it is characterised in that each raw medicinal material in described Chinese medicine Ratio of weight and number as follows: Radix Camelliae sinensis 29 parts, Flos clerodendri japonici 17 parts, Herba Salviae Cavaleriei 15 parts, Caulis et folium stauntoniae 32 Part, Herba Cichorii 25 parts, Herba Limoii Bicoloris 31 parts, Citrus chachiensis Hort. (C．Suavissima Tanaka) 18 parts, Semen clausenae lansii 12 parts, Eriosema himalaicum Ohashi 29 Part, Semen Bauhiniae championii 18 parts, Herba Osbeckiae 12 parts, Alectoria asiatica Du Rietz 35 parts, 7 parts of Fructus Elaeagni Angustifoliae, Shi Rong 29 parts, Fructus Ilicis Purpureae 21 parts, Streptopus simplex D. Don 19 parts, Polyalthia nemoralis A. D C. 32 parts, Rhizoma Gymnadeniae 25 parts, Radix Cinnamomi Burmanni 31 parts, gold Silk Caulis Akebiae 12 parts and Cyperus michelianus(L.) Link (Herba Cyperi Micheliani) 28 parts.

6. the Chinese medicine as described in claim 1 to 5, it is characterised in that the dosage form of described Chinese medicine is tablet, Its preparation method comprises the following steps:

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, add relative to mixture quality 2～ The determining alcohol of 4 times is the ethanol of 85～95%, is heated to reflux 1～3 hour, extracts, and filters acquisition first Extracting solution；Filter obtain medicinal residues add relative to the determining alcohol of described medicinal residues quality 1～2 times be 85～ The ethanol of 95%, is heated to reflux 1～3 hour, extracts, and filters and obtains the second extracting solution；Extract first Liquid and the second extracting solution merge, and concentrating under reduced pressure removes alcohol solvent, are dried, it is thus achieved that dry cream；

Second step, is placed in super micron mill pulverizing 1～2 hour by the dry cream that the first step obtains, and pulverizes, Sieve, it is thus achieved that 300 mesh～the micropowders of 400 mesh；

3rd step, the micropowders obtained by second step, add relative to its quality 0.1～0.3 times is micro- Crystalline cellulose, 0.05～0.15 times of lactose, starch of 0.1～0.3 times, sieve, mix homogeneously, pelletizes, It is dried, adds relative to micropowders quality 0.005～0.05 times of magnesium stearate, granulate, tabletting, system Become.

7. the Chinese medicine as described in claim 1 to 5, it is characterised in that the dosage form of described Chinese medicine is capsule Agent, its preparation method comprises the following steps:

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, add relative to mixture quality 2～ The determining alcohol of 4 times is the ethanol of 85～95%, is heated to reflux 1～3 hour, extracts, and filters acquisition first Extracting solution；Filter obtain medicinal residues add relative to the determining alcohol of described medicinal residues quality 1～2 times be 85～ The ethanol of 95%, is heated to reflux 1～3 hour, extracts, and filters and obtains the second extracting solution；Extract first Liquid and the second extracting solution merge, and concentrating under reduced pressure removes alcohol solvent, are dried, it is thus achieved that dry cream；

Second step, is placed in super micron mill pulverizing 1～2 hour by the dry cream that the first step obtains, and pulverizes, Sieve, it is thus achieved that 300 mesh～the micropowders of 400 mesh；

3rd step, is sequentially added into Pulvis Talci, magnesium stearate in the micropowders that second step obtains, carries out Mixing processes, and obtains capsule 's content；Described micropowders, magnesium stearate and talcous weight ratio are 100: 0.15～0.5:0.15～0.5, described capsule 's content is loaded in capsule housing, obtains capsule Agent finished product.

8. the preparation method of Chinese medicine described in a claim 1 to 5, it is characterised in that described Chinese medicine Dosage form is tablet, and its preparation method comprises the following steps:

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, add relative to mixture quality 2～ The determining alcohol of 4 times is the ethanol of 85～95%, is heated to reflux 1～3 hour, extracts, and filters acquisition first Extracting solution；Filter obtain medicinal residues add relative to the determining alcohol of described medicinal residues quality 1～2 times be 85～ The ethanol of 95%, is heated to reflux 1～3 hour, extracts, and filters and obtains the second extracting solution；Extract first Liquid and the second extracting solution merge, and concentrating under reduced pressure removes alcohol solvent, are dried, it is thus achieved that dry cream；

Second step, is placed in super micron mill pulverizing 1～2 hour by the dry cream that the first step obtains, and pulverizes, Sieve, it is thus achieved that 300 mesh～the micropowders of 400 mesh；

3rd step, the micropowders obtained by second step, add relative to its quality 0.1～0.3 times is micro- Crystalline cellulose, 0.05～0.15 times of lactose, starch of 0.1～0.3 times, sieve, mix homogeneously, pelletizes, It is dried, adds relative to micropowders quality 0.005～0.05 times of magnesium stearate, granulate, tabletting, system Become.

9. the preparation method of Chinese medicine described in a claim 1 to 5, it is characterised in that described Chinese medicine Dosage form is capsule, and its preparation method comprises the following steps:

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, add relative to mixture quality 2～ The determining alcohol of 4 times is the ethanol of 85～95%, is heated to reflux 1～3 hour, extracts, and filters acquisition first Extracting solution；Filter obtain medicinal residues add relative to the determining alcohol of described medicinal residues quality 1～2 times be 85～ The ethanol of 95%, is heated to reflux 1～3 hour, extracts, and filters and obtains the second extracting solution；Extract first Liquid and the second extracting solution merge, and concentrating under reduced pressure removes alcohol solvent, are dried, it is thus achieved that dry cream；

Second step, is placed in super micron mill pulverizing 1～2 hour by the dry cream that the first step obtains, and pulverizes, Sieve, it is thus achieved that 300 mesh～the micropowders of 400 mesh；

3rd step, is sequentially added into Pulvis Talci, magnesium stearate in the micropowders that second step obtains, carries out Mixing processes, and obtains capsule 's content；Described micropowders, magnesium stearate and talcous weight ratio are 100: 0.15～0.5:0.15～0.5, described capsule 's content is loaded in capsule housing, obtains capsule Agent finished product.