CN105963338B - Prevent and treat the herbal composite of cervical erosion - Google Patents
Prevent and treat the herbal composite of cervical erosion Download PDFInfo
- Publication number
- CN105963338B CN105963338B CN201610553426.9A CN201610553426A CN105963338B CN 105963338 B CN105963338 B CN 105963338B CN 201610553426 A CN201610553426 A CN 201610553426A CN 105963338 B CN105963338 B CN 105963338B
- Authority
- CN
- China
- Prior art keywords
- root
- herbal composite
- group
- cervical erosion
- herbal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/254—Acanthopanax or Eleutherococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The herbal composite of the present invention for preventing and treating cervical erosion is related to a kind of gynaecology's herbal composite, particularly a kind of herbal composite for preventing and treating cervical erosion.It is made up of the Chinese herbal medicine of following portions by weight：Valley dragon 60-90, charred CORTEX EUCOMMIAE 10-20, calcined CONCHA ARCAE 10-40, common pternopetalum root 3-6, trifoliate acanthopanax root or root-bark 2-12, hooker winghead root 2-11, Phoenix Tree Seed 1-2.Herbal composite of the present invention finds that model group vaginal mucosal epithelium inflammatory cell occurs and invades profit, thickens by the way that antipruritic, analgesia, anti-inflammatory, bacteriostatic test are studied display and had a significant effect by the influence experimental study of cervical erosion rat model；Rats in test groups inflammatory cell is invaded profit and substantially mitigated, and uterine mucosa erosion area is obviously reduced compared with XIAOMI SHUAN；This illustrates that therapeutic action of the herbal composite of the present invention to cervical erosion rat model is notable, and effect is superior to prior art.
Description
Technical field
The present invention relates to a kind of gynaecology's herbal composite, particularly a kind of Chinese herbal medicine combination for preventing and treating cervical erosion
Thing.
Background technology
The physiological structure feature of vagina determines its infection for being highly susceptible to exogenous virus and pathogen bacteria,
So that many women are suffering from different degrees of cervical disease, such as vulvitis, cervicitis, bacterial vaginosis BV, cervical erosion
And mycotic, trichomonas and nonspecific vaginitis even cervical carcinoma, oophoroma etc..Wherein, cervical erosion is cervical disease
Middle common disease, frequently-occurring disease, are the one of the main reasons for inducing cervical carcinoma.Cervical erosion not only increases patient suffering, and seriously
Influence the Health and Living quality of women.
At present, the treatment of cervical erosion is divided into physical therapy and medicinal treatment.Physical treatment is that current application is very extensive
A kind for the treatment of method, with short treating period, eutherapeutic advantage.Suitable for rotten to the corn area is larger and the deeper patient of inflammatory infiltration.
Conventional method has electricity to press method, laser therapy, cold therapy.Traditional leep knife (LEEP), focusing ultrasonic wave, micro-wave therapeutic, TMS
Optimize spectrotherapy, freezing, electron ion, carbon dioxide laser etc., most of principle for the treatment of is to utilize fuel factor or cold effect
It is denatured the histone of cervical erosion to come off, instead cambium.Therefore cause the cervical erosion wound after treatment big, palace
Neck head is stiff, nonelastic, allows patient by secondary injury, unrenewable physical therapy treatment, pair treatment are such as recurred in influence fertility
Greatly.Drug therapy is applied to that rotten to the corn area is smaller and the shallower patient of inflammatory infiltration.Medicine is broadly divided into Western medicine, Chinese medicine, and
Chinese and Western medicine is cooperateed with.But current drug therapy, generally existing weak curative effect, secondary treatment are big, the easy weak point such as recurrence after treatment.
The content of the invention
The problem of it is an object of the invention to exist to prior art solves can effectively prevent and treat uterine neck gruel there is provided one kind
Rotten herbal composite, to reduce or eliminate harm of the cervical erosion to WomanHealth.
The herbal composite of the present invention for preventing and treating cervical erosion, is made up of the Chinese herbal medicine of following portions by weight：River
Earthworm 60-90, charred CORTEX EUCOMMIAE 10-20, calcined CONCHA ARCAE 10-40, common pternopetalum root 3-6, trifoliate acanthopanax root or root-bark 2-12, hooker winghead root 2-11, Chinese parasol tree
Seeds of a tung oil tree 1-2.
Preferably it is made up of the Chinese herbal medicine of following portions by weight：
Valley dragon 75-85, charred CORTEX EUCOMMIAE 15-20, calcined CONCHA ARCAE 15-30, common pternopetalum root 3-5, trifoliate acanthopanax root or root-bark 5-10, the wing are first
Careless 6-9, Phoenix Tree Seed 1-2.
More preferably it is made up of the Chinese herbal medicine of following portions by weight：
Valley dragon 75, charred CORTEX EUCOMMIAE 17, calcined CONCHA ARCAE 17, common pternopetalum root 5, trifoliate acanthopanax root or root-bark 9, hooker winghead root 9, Phoenix Tree Seed 2.
The preparation method of the herbal composite of the present invention for preventing and treating cervical erosion, comprises the following steps：
（1）Prepare each clean dried raw material, each raw material is weighed by weight, it is standby；
（2）By step（1）In weigh raw material mixing insert decoction kettle in, add deionized water, big fire decoct 30-
45min, then 2-3h is cooked by slow fire, 200 mesh filters filtering decocting liquid collects filtrate, ointment shape is concentrated into evaporator i.e.
Can.
It is preferred that, the herbal composite is external preparation, in being gel, ointment, suppository or cleaning fluid
Any one.
Herbal composite of the present invention passes through to antipruritic, analgesia, anti-inflammatory, bacteriostatic test studies have shown that institute of the present invention
State herbal composite to have a significant effect, and found by the influence experimental study of cervical erosion rat model, model group
There is vaginal mucosal epithelium inflammatory cell and invade profit, thicken；Rats in test groups inflammatory cell is invaded profit and substantially mitigated, and uterine mucosa is rotten to the corn
Area is obviously reduced compared with XIAOMI SHUAN；This illustrates therapeutic action of the herbal composite of the present invention to cervical erosion rat model
Significantly, effect is superior to prior art.
Embodiment
Experimental example 1
1st, valley dragon 65g, charred CORTEX EUCOMMIAE 12g, calcined CONCHA ARCAE 15g, common pternopetalum root 3g, trifoliate acanthopanax root or root-bark 3g, hooker winghead root 3g, Chinese parasol tree are prepared
Sub- 1g.
2nd, clean up and each dried above-mentioned raw material, then above-mentioned raw materials are mixed and inserted in decoction kettle, are added
Deionized water, big fire decocts 30-45min, then is cooked by slow fire 2-3h, and 200 mesh filters filtering decocting liquid collects filtrate, in evaporation
Ointment shape is concentrated into device.
Experimental example 2
1st, valley dragon 90g, charred CORTEX EUCOMMIAE 20g, calcined CONCHA ARCAE 35g, common pternopetalum root 5g, trifoliate acanthopanax root or root-bark 10g, hooker winghead root 10g, Chinese parasol tree are prepared
Seeds of a tung oil tree 2g.
2nd, clean up and each dried above-mentioned raw material, then above-mentioned raw materials are mixed and inserted in decoction kettle, are added
Deionized water, big fire decocts 30-45min, then is cooked by slow fire 2-3h, and 200 mesh filters filtering decocting liquid collects filtrate, in evaporation
Ointment shape is concentrated into device.
Experimental example 3
1st, valley dragon 75g, charred CORTEX EUCOMMIAE 15g, calcined CONCHA ARCAE 15g, common pternopetalum root 3g, trifoliate acanthopanax root or root-bark 5g, hooker winghead root 6g, Chinese parasol tree are prepared
Sub- 1g.
2nd, clean up and each dried above-mentioned raw material, then above-mentioned raw materials are mixed and inserted in decoction kettle, are added
Deionized water, big fire decocts 30-45min, then is cooked by slow fire 2-3h, and 200 mesh filters filtering decocting liquid collects filtrate, in evaporation
Ointment shape is concentrated into device.
Experimental example 4
1st, valley dragon 85g, charred CORTEX EUCOMMIAE 20g, calcined CONCHA ARCAE 30g, common pternopetalum root 5g, trifoliate acanthopanax root or root-bark 10, hooker winghead root 9g, Chinese parasol tree are prepared
Sub- 2g.
2nd, clean up and each dried above-mentioned raw material, then above-mentioned raw materials are mixed and inserted in decoction kettle, are added
Deionized water, big fire decocts 30-45min, then is cooked by slow fire 2-3h, and 200 mesh filters filtering decocting liquid collects filtrate, in evaporation
Ointment shape is concentrated into device.
Experimental example 5
1st, valley dragon 75g, charred CORTEX EUCOMMIAE 17g, calcined CONCHA ARCAE 17g, common pternopetalum root 5g, trifoliate acanthopanax root or root-bark 9g, hooker winghead root 9g, Chinese parasol tree are prepared
Sub- 2g.
2nd, clean up and each dried above-mentioned raw material, then above-mentioned raw materials are mixed and inserted in decoction kettle, are added
Deionized water, big fire decocts 30-45min, then is cooked by slow fire 2-3h, and 200 mesh filters filtering decocting liquid collects filtrate, in evaporation
Ointment shape is concentrated into device.
Experimental example 6
First, to the influence of cavy itch-threshold caused by histamine phosphate
Test method and result：
1. animal packet：Cavy 50, body weight 250-300g, female.It is randomly divided into 5 groups, every group 10, i.e. Chinese medicine
Composition low dose group (1g/100mL), middle dose group (5g/100mL), high dose group (10g/100mL), FUFANG HUANGSONG XIYE
Group (stoste), and blank group (0.4% sodium carboxymethylcellulose).
Instep after 2. the basic, normal, high dosage group cavy of control group cavy, FUFANG HUANGSONG XIYE group cavy, Chinese medicine composition is right
Shaving is simultaneously coated with relative medicine 1 time, and shaving area is about 1cm2, and coating capacity is 0.2ml or so, uses mouse stomach pin
Head is equably coated in skin of unhairing surface, is contacted 4 hours with gauze wrapped immobilization with adhesive tape；Second day control group, compound yellow pine
Instep is abraded with coarse sandpaper after the basic, normal, high dosage group cavy of washing lotion group, Chinese medicine composition is right, using oozing of blood as degree, and is coated with phase
Answer medicine 1 time, coating capacity is 0.2ml or so, and skin of unhairing surface is equably coated in mouse stomach syringe needle；30 points
Zhong Hou, cleans the surface of a wound, affected part is gently dried with gauze, then coats the histamine phosphate of concentration 0.02%, every three minutes once, often
Secondary is 0.05ml/, when licking metapedes up to there is cavy, and it is itch-threshold, each group cavy to record the histamine phosphate total amount given
Itch-threshold see the table below：
Table 1：Influence of the herbal composite to histamine phosphate induced mice itch-threshold
As can be seen from the above table, in addition to herbal composite low dose group, the herbal composite of middle and high dosage group and multiple
Cavy itch-threshold caused by Fang Huangsong washing lotions group can improve histamine phosphate, illustrates that this medicine has obvious itching-relieving action.
2nd, to mouse analgesic activity influence (writhing method)：
1. animal packet：Mouse, 60, Kunming kind 18-22g, female.Animal is randomly divided into 6 groups, every group 10
Only, i.e. the basic, normal, high dosage group of herbal composite, Sauteralgyl group, model group and control group.
2. observation index：Model group and control group give 0.4% sodium carboxymethylcellulose, and the equal vagina of other each groups is given
Relative medicine 0.2ml is given, introitus is closed with vaseline；After administration 60 minutes, except control group intraperitoneal injection of saline,
0.6% acetic acid 0.2ml is injected intraperitoneally in each mouse, observes each group in 10 minutes and writhing response mouse number of elements (belly occurs
Indent, stretching, extension hind leg, buttocks are raised) and number of times, as a result it see the table below.
Influence of the herbal composite of table 2 to mouse analgesic activity
As can be seen from the above table, 0.6% glacial acetic acid of intraperitoneal injection can cause mouse pain reaction occur, and it is success to illustrate modeling
, the herbal composite and Sauteralgyl of basic, normal, high dosage group can obviously reduce mouse writhing quantity, illustrate that this medicine has substantially
The effect of town pain.
3rd, the influence (auricle edema method) acted on mouse corrosion disease
1. animal packet：Mouse, 60, Kunming kind 18-22g, female.Animal is randomly divided into 6 groups, every group 10
Only, i.e. the basic, normal, high dosage group of herbal composite, prednisone group, FUFANG HUANGSONG XIYE group and control group.
2. observation index：Control group give 0.4% sodium carboxymethylcellulose -+, the equal vagina of other each groups is given accordingly
Medicine 0.2ml, introitus is closed with vaseline；30 minutes rear left auricles apply 100% dimethylbenzene 0.02ml/ only, 4 hours
Afterwards, mouse is pulled into cervical vertebra to put to death, cuts two ears along auricle baseline, circle is laid at same position respectively with the straight card punch of 8mm
Auricle, weighing scale to test twisting force is weighed；It is swelling again that auris dextra piece is subtracted per the left auricle of mouse.As a result it see the table below.
Influence of the herbal composite of table 3 to mice auricle swelling
As can be seen from the above table, the herbal composite and prednisone of basic, normal, high dosage group have to mice auricle swelling degree
Substantially mitigate, i.e. paraxylene induced mice auricle inflammation has obvious inhibitory action.
4th, to the influence of rat bacterial vaginitis caused by S. aureus L-forms
Test objective：By injury rats vaginal wall along with inoculation S. aureus L-forms cause the scorching model of rat vagina, medicine is given
Thing, observation medicine is to the integral status of animal, vagina congestion and edema, vaginal smear examination leucocyte and bacterium and pathologic finding
As a result change, to weigh therapeutic action of the medicine to bacterial vaginitis.
1. animal packet：Animal is randomly divided into 6 groups, every group 10, the i.e. basic, normal, high dosage of herbal composite
Group, FUFANG HUANGSONG XIYE group, model group and Normal group.
2. observation index：With No. 7 blunt syringe needles, every mouse draws 30 to each group rat from inside to outside on the vaginal wall
Secondary, by one man operation, to ensure dynamics uniformity, in addition to control group, other each groups inject 108/L S. aureus L-forms liquid
0.2ml, introitus is sealed with vaseline；In addition to control group, see that obvious WBC increases under remaining each group mirror, smear within second day
In have a large amount of S. aureus L-forms, vaginal fluid increases, and vagina mucosa is congested, swelling, and surface is covered with white thing；It is right from 3rd day
0.4% sodium carboxymethylcellulose is given according to group, the equal vagina of other each groups gives relative medicine 0.2ml, vagina is closed with vaseline
Mouthful；Visually observe the integrality of each group animal, vagina daily and whether there is congested swelling, and in plate coating checking its vaginal fluid
Inflammatory cell and bacterium, administration in the 7th day make vaginal fluid smear after 5 hours, see WBC and S. aureus L-forms；De- cervical vertebra puts to death big
Mouse, takes out its vagina, observes its vagina mucosa whether there is congested, oedema situation, then vagina is put into BolinShi fixers,
Send and do check pathological section；
3rd, vaginitis therapeutic evaluation is formulated using the lesion gross examination of skeletal muscle of vagina tissue as criterion, see the table below.
The S. aureus L-forms vaginitis rat standards of grading of table 4
3rd, result：
(1) vagina local patholoic change is visually observed：There is obvious congested, swelling in the 1-3 days vaginas after rat moulding,
Secretion rolls up, and surface covers a large amount of white sticky secretion.In the 1-3 days vaginal fluid smears, it is seen that have big
The inflammatory cell and S. aureus L-forms of amount, comprehensive scores do not have notable difference between model sets up each group.Start within the 3rd day administration in modeling,
Greatly, middle dose group was in administration the 3rd day, and vagina contrafluxion, oedema, secretion, mucosal erosion mitigate, and have in 4-5 days
Slight congested swelling, except having mild hyperaemia swelling individually, remaining recovers normal to the 7th day vagina lesion, comprehensive scores and mould
Type group, control group relatively have pole significant difference.Small dose group and positive drug group lesion when being administered 4-5 days also substantially mitigate,
At the 7th day, vagina local patholoic change majority was returned to normal, and comprehensive scores are compared also with model group, Normal group has inspection aobvious
Sex differernce is write, specifically be see the table below.
Influence of the herbal composite of table 5 to S. aureus L-forms vaginitis lesion comprehensive scores
(2) vaginal smear examination：Vaginal fluid smear is positive after each assembly molding, it is seen that have substantial amounts of golden Portugal
Bacterium and Exfoliative cells and inflammatory cell.The 7th day after administration, model group 10,0 smear of Normal group is visible S. aureus L-forms
And a large amount of inflammatory cells and downright bad Exfoliative cells.Administration group is visible except herbal composite small dose group 3 and positive drug
Have outside S. aureus L-forms, the big middle dose group of herbal composite, which only has 1 and 2, there are S. aureus L-forms, rarely seen to have a small amount of inflammatory cell and de-
The epithelial cell fallen, concrete condition see the table below.
Influence of the table 6 to vaginal fluid smear (WBC and S. aureus L-forms)
(3) histological examination：Each layer tissue structure of matrix group is normal, and epithelium is rotten to the corn without breakage, and mucous membrane has no congested
And oedema, submucosa and muscle layer no abnormality seen；There is obvious congestion and edema, upper micromicro in model group vagina mucosa lower floor and muscle layer
See that part is incomplete；Low dose group mucous membrane and submucosa congestion and edema mitigate, and have 1 epithelium incompleteness；Middle dose group part is big
Mouse vagina mucosa visible hyperemia swelling, portion weave structure recovers normal；High dose group rat portions vagina mucosa, which has, slightly to be filled
Watery blood swells, and portion weave structure recovers normal completely；Positive drug group rat portions vagina mucosa has mild hyperaemia oedema, part group
Knit structure and recover normal completely.
5th, to the influence of cervical erosion rat model
Healthy female rat 48, is randomly divided into blank control group, model control group, positive controls, test group.Take
Phenol 30mL, Arabic gum 40g, distilled water 50mL is made into Hydroxybenzene mucilage, cuts pin with taper vein and enters the injection of people's rat vagina
Hydroxybenzene mucilage 0.2mL, 1 time/3 days, totally 4 times.After modeling success, start drug treatment.The side of each group rat according to the form below
Formula gives tested material.
Table 7 is grouped and administering mode
Each group is administered once/day, and successive administration 7 days puts to death animal on the 8th day, takes its vagina, uterus to visually observe and carry out
Histopathologic examination.
Dissection rat takes uterine tissue to visually observe, and model control group rat vagina, cervical tissue are congested, oedema.Treatment
Group has a certain degree of improvement.Pathologic finding, the vagina and uterine tissue of blank control group rat have no obvious lesion, model
There is vaginal mucosal epithelium inflammatory cell and invades profit in group, thickens.Rats in test groups inflammatory cell is invaded profit and substantially mitigated, and uterine mucosa is rotten
Rotten area is obviously reduced compared with XIAOMI SHUAN.Therapeutic action of the Chinese medicine suppository of this explanation present invention to cervical erosion rat model shows
Write, better than prior art.Concrete outcome see the table below.
Pathological examination of the table 8 to uterus erosion rat model
Claims (3)
1. prevent and treat the herbal composite of cervical erosion, it is characterised in that be made up of the Chinese herbal medicine of following portions by weight：Valley dragon
60-90, charred CORTEX EUCOMMIAE 10-20, calcined CONCHA ARCAE 10-40, common pternopetalum root 3-6, trifoliate acanthopanax root or root-bark 2-12, hooker winghead root 2-11, Phoenix Tree Seed
1-2.
2. the herbal composite as claimed in claim 1 for preventing and treating cervical erosion, it is characterised in that by following portions by weight
Chinese herbal medicine is constituted：Valley dragon 75-85, charred CORTEX EUCOMMIAE 15-20, calcined CONCHA ARCAE 15-30, common pternopetalum root 3-5, trifoliate acanthopanax root or root-bark 5-10, the wing
First grass 6-9, Phoenix Tree Seed 1-2.
3. the herbal composite as claimed in claim 2 for preventing and treating cervical erosion, it is characterised in that by following portions by weight
Chinese herbal medicine is constituted：Valley dragon 75, charred CORTEX EUCOMMIAE 17, calcined CONCHA ARCAE 17, common pternopetalum root 5, trifoliate acanthopanax root or root-bark 9, hooker winghead root 9, Phoenix Tree Seed 2.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610553426.9A CN105963338B (en) | 2016-07-14 | 2016-07-14 | Prevent and treat the herbal composite of cervical erosion |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610553426.9A CN105963338B (en) | 2016-07-14 | 2016-07-14 | Prevent and treat the herbal composite of cervical erosion |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105963338A CN105963338A (en) | 2016-09-28 |
| CN105963338B true CN105963338B (en) | 2017-08-11 |
Family
ID=56951675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610553426.9A Expired - Fee Related CN105963338B (en) | 2016-07-14 | 2016-07-14 | Prevent and treat the herbal composite of cervical erosion |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105963338B (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526342A (en) * | 2012-02-02 | 2012-07-04 | 李坤 | Traditional Chinese medicine preparation for treating chronic cervicitis |
-
2016
- 2016-07-14 CN CN201610553426.9A patent/CN105963338B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526342A (en) * | 2012-02-02 | 2012-07-04 | 李坤 | Traditional Chinese medicine preparation for treating chronic cervicitis |
Non-Patent Citations (3)
| Title |
|---|
| 土家族药紫金砂的生药学研究;汪植等;《时珍国医国药》;20070920;第18卷(第09期);全文 * |
| 带下治验两则;张佃民;《山东医药》;19790720(第07期);第46页右栏第1-5段 * |
| 近年来中医药治疗子宫颈癌的概况;李应存等;《甘肃中医》;19951231;第09卷(第01期);全文 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105963338A (en) | 2016-09-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102091203A (en) | External traditional Chinese medicine preparation for treating chronic wounds and preparation method thereof | |
| CN103751663B (en) | A kind of Chinese medicine for external application treating anal eczema and preparation method thereof | |
| CN101744976B (en) | Sterilizing and antipruritic lotion and preparation method thereof | |
| CN110179918A (en) | Treat vaginitis, cervicitis, the Chinese medicine of cervical erosion and preparation and preparation method | |
| CN102145073B (en) | Pharmaceutical composition for treating gynecological inflammation and preparation method thereof | |
| CN104274601A (en) | External traditional Chinese medicinal composition for treating xerophthalmia and preparation method thereof | |
| CN102772712B (en) | Traditional Chinese medicine composition for treating heat-toxicity, flourishing and blood stasis type diabetic foot | |
| CN105963338B (en) | Prevent and treat the herbal composite of cervical erosion | |
| CN100589834C (en) | Therapeutic agent for respiration diseases | |
| CN102988844A (en) | Gynaecological gel and extraction method thereof | |
| CN103721138B (en) | A kind of traditional Chinese medicine for external application and its preparation method treating rosacea | |
| CN104324317B (en) | A kind of Chinese medicine composition and medical usage for treating fibroid | |
| CN102327360B (en) | Gel preparation for treating cervical erosion and preparation method thereof | |
| CN109925367A (en) | A kind of prevention and treatment hemorrhoid fit perfectly | |
| CN103169846B (en) | Skin burn-scald spraying agent and preparation method thereof | |
| CN102727794B (en) | Traditional Chinese medical prescription for treating burn and scald, traumatic injury and rheumatism bone pain | |
| CN102274328B (en) | Medicament for treating psoriasis and preparation method thereof | |
| CN103536706B (en) | A kind of Chinese medicine for the treatment of trimester of pregnancy monilial vaginitis smokes lotion | |
| CN105596480A (en) | Traditional Chinese medicine composition for treating rhinitis as well as preparation method thereof and method for preparing collunarium | |
| CN104606402B (en) | A kind of Chinese medicine composition, preparation and preparation method, purposes | |
| CN102068572B (en) | Pedate pinallia jackinthepulpit rhizome externally applied preparation for treating bruises | |
| CN102416087A (en) | Chinese medicinal composition for treating pelvic inflammatory disease and preparation method as well as application thereof | |
| CN102058755A (en) | Pharmaceutical composition for treatment of psoriasis | |
| CN108186737B (en) | External drop for treating paronychia and preparation method thereof | |
| CN117503793A (en) | Application of burdock root polysaccharide in preparation of medicine for treating burn |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB03 | Change of inventor or designer information | ||
| CB03 | Change of inventor or designer information |
Inventor after: Li Mingjie Inventor before: Li Mingjie Inventor before: Wang Mingquan Inventor before: Wang Zhikun |
|
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20170710 Address after: 723000 Far East Mansion, Wangjiang Road, Hantai District, Shaanxi, Hanzhoung Applicant after: Hanzhoung Shaanxi Qin Hui Biomedical Technology Co., Ltd. Address before: 723000 Shaanxi Province, Hanzhoung City Bank of the big silver Ditch Bridge District, building 4, unit 601, Room 201 Applicant before: Li Mingjie |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170811 Termination date: 20200714 |