CN105960239A - 利用含有噻吩并三唑并二氮杂*化合物的药物制剂治疗白血病的方法 - Google Patents

利用含有噻吩并三唑并二氮杂*化合物的药物制剂治疗白血病的方法 Download PDF

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Publication number
CN105960239A
CN105960239A CN201480065213.0A CN201480065213A CN105960239A CN 105960239 A CN105960239 A CN 105960239A CN 201480065213 A CN201480065213 A CN 201480065213A CN 105960239 A CN105960239 A CN 105960239A
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China
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compound
thienotriazolodiazepine
formula
solid dispersion
pharmaceutically acceptable
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CN201480065213.0A
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English (en)
Chinese (zh)
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马里亚·E·里韦罗
埃里克·雷蒙德
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Oncoethix GmbH
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Oncoethix GmbH
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201480065213.0A 2013-11-27 2014-11-26 利用含有噻吩并三唑并二氮杂*化合物的药物制剂治疗白血病的方法 Pending CN105960239A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361909702P 2013-11-27 2013-11-27
US61/909,702 2013-11-27
US201462012128P 2014-06-13 2014-06-13
US62/012,128 2014-06-13
US201462080804P 2014-11-17 2014-11-17
US62/080,804 2014-11-17
PCT/EP2014/075709 WO2015078929A1 (en) 2013-11-27 2014-11-26 Method of treating leukemia using pharmaceutical formulation containing thienotriazolodiazepine compounds

Publications (1)

Publication Number Publication Date
CN105960239A true CN105960239A (zh) 2016-09-21

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CN201480065213.0A Pending CN105960239A (zh) 2013-11-27 2014-11-26 利用含有噻吩并三唑并二氮杂*化合物的药物制剂治疗白血病的方法

Country Status (6)

Country Link
US (1) US9757385B2 (https=)
EP (1) EP3074018A1 (https=)
JP (1) JP2016538310A (https=)
KR (1) KR20160079823A (https=)
CN (1) CN105960239A (https=)
WO (1) WO2015078929A1 (https=)

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CN108743591A (zh) * 2018-07-17 2018-11-06 苏州大学 用于治疗癌症的药物组合物及其应用
CN116098870A (zh) * 2023-04-10 2023-05-12 上海赛默罗生物科技有限公司 α5-GABAA受体调节剂的固体分散体及其制备方法

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WO2015014998A1 (en) * 2013-08-01 2015-02-05 Oncoethix Sa Pharmaceutical formulation containing thienotriazolodiazepine compounds
JP2017514907A (ja) * 2014-05-02 2017-06-08 オンコエシックス ゲーエムベーハー チエノトリアゾロジアゼピン化合物を用いる耐性非ホジキンリンパ腫、髄芽腫及び／又はａｌｋ＋非小細胞肺癌の治療方法
CN107073014A (zh) * 2014-05-02 2017-08-18 翁科埃斯克斯有限公司 利用噻吩并三唑并二氮杂*化合物治疗急性髓细胞白血病和/或急性淋巴细胞性白血病的方法
CN107427524A (zh) * 2014-08-28 2017-12-01 翁科埃斯克斯有限公司 利用包含噻吩并三唑并二氮杂*化合物的药物组合物治疗急性髓细胞白血病或急性淋巴性白血病的方法
US10702517B2 (en) 2015-04-22 2020-07-07 Celgene Quanticel Research, Inc. Bromodomain inhibitor
AU2016304856B8 (en) 2015-08-10 2021-02-18 Dana-Farber Cancer Institute, Inc. Mechanism of resistance to BET bromodomain inhibitors
EP3795563B1 (en) 2016-03-31 2024-07-17 Oncternal Therapeutics, Inc. Indoline analogs and uses thereof
CA3029851A1 (en) * 2016-07-29 2018-02-01 Oncternal Therapeutics, Inc. Uses of indoline compounds such as tk216 for the treatment of cancer
JP7129973B2 (ja) * 2016-10-20 2022-09-02 セルジーン クオンティセル リサーチ，インク． ブロモドメイン阻害剤
MX2020013608A (es) 2018-06-13 2021-03-09 Worg Pharmaceuticals Hangzhou Co Ltd Preparacion de derivados de triazepina condensados y su uso como inhibidores de bet.
KR20240028420A (ko) 2021-06-08 2024-03-05 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 항암 화합물
WO2023229535A1 (en) 2022-05-27 2023-11-30 Engine Biosciences Pte. Ltd. Bet polypeptide therapeutic agents for generating synthetic lethality in tumors

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