CN105943978A - Medicine for treating gynecologic inflammation and preparation method of medicine - Google Patents
Medicine for treating gynecologic inflammation and preparation method of medicine Download PDFInfo
- Publication number
- CN105943978A CN105943978A CN201610321041.XA CN201610321041A CN105943978A CN 105943978 A CN105943978 A CN 105943978A CN 201610321041 A CN201610321041 A CN 201610321041A CN 105943978 A CN105943978 A CN 105943978A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- preparation
- medicine
- pill
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 38
- 238000002360 preparation method Methods 0.000 title claims abstract description 31
- 206010061218 Inflammation Diseases 0.000 title claims abstract description 15
- 230000004054 inflammatory process Effects 0.000 title claims abstract description 15
- 229940079593 drug Drugs 0.000 title claims description 22
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 23
- 239000006187 pill Substances 0.000 claims abstract description 23
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 claims abstract description 17
- 241000628997 Flos Species 0.000 claims description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 20
- QQILFGKZUJYXGS-UHFFFAOYSA-N Indigo dye Chemical compound C1=CC=C2C(=O)C(C3=C(C4=CC=CC=C4N3)O)=NC2=C1 QQILFGKZUJYXGS-UHFFFAOYSA-N 0.000 claims description 19
- 238000000034 method Methods 0.000 claims description 18
- 239000000843 powder Substances 0.000 claims description 18
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 claims description 17
- 239000002994 raw material Substances 0.000 claims description 17
- 238000003809 water extraction Methods 0.000 claims description 14
- 238000002156 mixing Methods 0.000 claims description 10
- 230000001954 sterilising effect Effects 0.000 claims description 10
- 238000004659 sterilization and disinfection Methods 0.000 claims description 10
- 239000007788 liquid Substances 0.000 claims description 7
- 238000002425 crystallisation Methods 0.000 claims description 6
- 230000008025 crystallization Effects 0.000 claims description 6
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 claims description 5
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 claims description 5
- 240000004460 Tanacetum coccineum Species 0.000 claims description 5
- 235000008384 feverfew Nutrition 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 230000005855 radiation Effects 0.000 claims description 5
- -1 Alumen Chemical compound 0.000 claims description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 4
- 239000006185 dispersion Substances 0.000 claims description 4
- 238000000605 extraction Methods 0.000 claims description 4
- 239000012567 medical material Substances 0.000 claims description 4
- NOOLISFMXDJSKH-UHFFFAOYSA-N p-menthan-3-ol Chemical compound CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims description 4
- 230000000694 effects Effects 0.000 abstract description 35
- 210000001215 vagina Anatomy 0.000 abstract description 13
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 12
- 208000003251 Pruritus Diseases 0.000 abstract description 7
- 208000002193 Pain Diseases 0.000 abstract description 5
- 230000001737 promoting effect Effects 0.000 abstract description 3
- 230000002175 menstrual effect Effects 0.000 abstract description 2
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract 2
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 1
- 241000205585 Aquilegia canadensis Species 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 235000017443 Hedysarum boreale Nutrition 0.000 abstract 1
- 235000007858 Hedysarum occidentale Nutrition 0.000 abstract 1
- 235000000177 Indigofera tinctoria Nutrition 0.000 abstract 1
- 241001676573 Minium Species 0.000 abstract 1
- 241001502500 Trichomonadida Species 0.000 abstract 1
- 230000000740 bleeding effect Effects 0.000 abstract 1
- 229940116229 borneol Drugs 0.000 abstract 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 1
- 239000001947 glycyrrhiza glabra rhizome/root Substances 0.000 abstract 1
- 230000012010 growth Effects 0.000 abstract 1
- 230000008821 health effect Effects 0.000 abstract 1
- 229940097275 indigo Drugs 0.000 abstract 1
- COHYTHOBJLSHDF-UHFFFAOYSA-N indigo powder Natural products N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 abstract 1
- 230000007803 itching Effects 0.000 abstract 1
- 230000003020 moisturizing effect Effects 0.000 abstract 1
- 230000017423 tissue regeneration Effects 0.000 abstract 1
- 231100000614 poison Toxicity 0.000 description 11
- 201000010099 disease Diseases 0.000 description 10
- 239000003440 toxic substance Substances 0.000 description 10
- 230000001717 pathogenic effect Effects 0.000 description 7
- 206010007247 Carbuncle Diseases 0.000 description 5
- 206010046914 Vaginal infection Diseases 0.000 description 5
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 244000045947 parasite Species 0.000 description 5
- 244000052769 pathogen Species 0.000 description 5
- 201000004624 Dermatitis Diseases 0.000 description 4
- 208000025865 Ulcer Diseases 0.000 description 4
- 208000010668 atopic eczema Diseases 0.000 description 4
- 206010008323 cervicitis Diseases 0.000 description 4
- 238000001035 drying Methods 0.000 description 4
- 230000008961 swelling Effects 0.000 description 4
- 231100000397 ulcer Toxicity 0.000 description 4
- 208000006374 Uterine Cervicitis Diseases 0.000 description 3
- 206010047799 Vulvovaginitis trichomonal Diseases 0.000 description 3
- 208000002399 aphthous stomatitis Diseases 0.000 description 3
- 239000000796 flavoring agent Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 206010063409 Acarodermatitis Diseases 0.000 description 2
- 206010068402 Cervix inflammation Diseases 0.000 description 2
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 2
- 206010010904 Convulsion Diseases 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- 208000015220 Febrile disease Diseases 0.000 description 2
- 206010017553 Furuncle Diseases 0.000 description 2
- 208000000616 Hemoptysis Diseases 0.000 description 2
- 206010062717 Increased upper airway secretion Diseases 0.000 description 2
- 206010023126 Jaundice Diseases 0.000 description 2
- 206010028116 Mucosal inflammation Diseases 0.000 description 2
- 241000517307 Pediculus humanus Species 0.000 description 2
- 206010035664 Pneumonia Diseases 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 241000447727 Scabies Species 0.000 description 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 2
- 201000008100 Vaginitis Diseases 0.000 description 2
- 201000007096 Vulvovaginal Candidiasis Diseases 0.000 description 2
- 241000607479 Yersinia pestis Species 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 239000003908 antipruritic agent Substances 0.000 description 2
- 230000036461 convulsion Effects 0.000 description 2
- 208000002173 dizziness Diseases 0.000 description 2
- 208000001848 dysentery Diseases 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 239000003205 fragrance Substances 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000023597 hemostasis Effects 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 208000026435 phlegm Diseases 0.000 description 2
- 239000002574 poison Substances 0.000 description 2
- 208000005687 scabies Diseases 0.000 description 2
- 239000011593 sulfur Substances 0.000 description 2
- 229910052717 sulfur Inorganic materials 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- DTGKSKDOIYIVQL-QXFUBDJGSA-N (-)-borneol Chemical compound C1C[C@]2(C)[C@H](O)C[C@H]1C2(C)C DTGKSKDOIYIVQL-QXFUBDJGSA-N 0.000 description 1
- 229930006703 (-)-borneol Natural products 0.000 description 1
- 206010003011 Appendicitis Diseases 0.000 description 1
- 208000006400 Arbovirus Encephalitis Diseases 0.000 description 1
- 206010003693 Atrophic vulvovaginitis Diseases 0.000 description 1
- 208000004429 Bacillary Dysentery Diseases 0.000 description 1
- 208000004926 Bacterial Vaginosis Diseases 0.000 description 1
- 241001252601 Blumea Species 0.000 description 1
- 241000255789 Bombyx mori Species 0.000 description 1
- 241001674345 Callitropsis nootkatensis Species 0.000 description 1
- 201000009030 Carcinoma Diseases 0.000 description 1
- 206010008479 Chest Pain Diseases 0.000 description 1
- 208000010445 Chilblains Diseases 0.000 description 1
- 241000723346 Cinnamomum camphora Species 0.000 description 1
- 206010010726 Conjunctival oedema Diseases 0.000 description 1
- 206010012374 Depressed mood Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 206010014080 Ecchymosis Diseases 0.000 description 1
- 206010052369 Encephalitis lethargica Diseases 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 241000498255 Enterobius vermicularis Species 0.000 description 1
- 201000000297 Erysipelas Diseases 0.000 description 1
- 206010017915 Gastroenteritis shigella Diseases 0.000 description 1
- 208000012671 Gastrointestinal haemorrhages Diseases 0.000 description 1
- 208000008454 Hyperhidrosis Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010020880 Hypertrophy Diseases 0.000 description 1
- 208000015817 Infant Nutrition disease Diseases 0.000 description 1
- 206010024229 Leprosy Diseases 0.000 description 1
- 206010025421 Macule Diseases 0.000 description 1
- 201000005505 Measles Diseases 0.000 description 1
- 201000010927 Mucositis Diseases 0.000 description 1
- 208000005647 Mumps Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 206010034038 Parotitis Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 206010040047 Sepsis Diseases 0.000 description 1
- 241000130764 Tinea Species 0.000 description 1
- 208000002474 Tinea Diseases 0.000 description 1
- 206010046814 Uterine prolapse Diseases 0.000 description 1
- 208000037009 Vaginitis bacterial Diseases 0.000 description 1
- 208000005946 Xerostomia Diseases 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 201000010442 acute cervicitis Diseases 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- RAWGYCTZEBNSTP-UHFFFAOYSA-N aluminum potassium Chemical compound [Al].[K] RAWGYCTZEBNSTP-UHFFFAOYSA-N 0.000 description 1
- 229910052934 alunite Inorganic materials 0.000 description 1
- 239000010424 alunite Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000002924 anti-infective effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 201000009361 ascariasis Diseases 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000003679 cervix uteri Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 201000003988 chronic cervicitis Diseases 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000007123 defense Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 206010013781 dry mouth Diseases 0.000 description 1
- 206010014599 encephalitis Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 206010014881 enterobiasis Diseases 0.000 description 1
- 206010015037 epilepsy Diseases 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 229940011871 estrogen Drugs 0.000 description 1
- 239000000262 estrogen Substances 0.000 description 1
- 208000011404 female reproductive system disease Diseases 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 208000014617 hemorrhoid Diseases 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 230000037315 hyperhidrosis Effects 0.000 description 1
- 210000003026 hypopharynx Anatomy 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000003780 keratinization Effects 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 230000001050 lubricating effect Effects 0.000 description 1
- 201000007227 lymph node tuberculosis Diseases 0.000 description 1
- HCWCAKKEBCNQJP-UHFFFAOYSA-N magnesium orthosilicate Chemical compound [Mg+2].[Mg+2].[O-][Si]([O-])([O-])[O-] HCWCAKKEBCNQJP-UHFFFAOYSA-N 0.000 description 1
- 239000000391 magnesium silicate Substances 0.000 description 1
- 229910052919 magnesium silicate Inorganic materials 0.000 description 1
- 235000019792 magnesium silicate Nutrition 0.000 description 1
- 208000004396 mastitis Diseases 0.000 description 1
- 210000004914 menses Anatomy 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 208000010805 mumps infectious disease Diseases 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 206010029410 night sweats Diseases 0.000 description 1
- 230000036565 night sweats Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 201000010808 postmenopausal atrophic vaginitis Diseases 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 230000001047 pyretic effect Effects 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 208000013223 septicemia Diseases 0.000 description 1
- 201000005113 shigellosis Diseases 0.000 description 1
- 210000005125 simple columnar epithelium Anatomy 0.000 description 1
- 206010040872 skin infection Diseases 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 206010044008 tonsillitis Diseases 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- KPZTWMNLAFDTGF-UHFFFAOYSA-D trialuminum;potassium;hexahydroxide;disulfate Chemical compound [OH-].[OH-].[OH-].[OH-].[OH-].[OH-].[Al+3].[Al+3].[Al+3].[K+].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O KPZTWMNLAFDTGF-UHFFFAOYSA-D 0.000 description 1
- 201000002327 urinary tract obstruction Diseases 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 201000002498 viral encephalitis Diseases 0.000 description 1
- 210000003905 vulva Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/12—Magnesium silicate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/634—Forsythia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/904—Stemonaceae (Stemona family), e.g. croomia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Neurosurgery (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a medicine for treating gynecologic inflammation. The medicine is prepared from the following medicinal materials in parts by weight: 0.1-4 parts of borneol, 0.3-5 parts of minium, 0.2-10 parts of natural indigo, 1-15 parts of talcum powder, 0.3-15 parts of alumen, 1-17 parts of licorice root, 2-20 parts of cortex phellodendri, 1-10 parts of radix scutellariae, 5-15 parts of honeysuckle flowers, 2-17 parts of fructus forsythiae, 1-10 parts of radix stemonae, 1-15 parts of Radix Arnebiae seu Lithospermi, and 2-17 parts of radix sophorae flavescentis. A preparation method comprises the preparation of pills and preparation of aqueous preparations. The medicine has the efficacies of killing bacteria and resisting trichomonads, clearing away heat and toxic materials, removing slough and promoting growth of tissue regeneration, relieving pain and stopping itching, removing peculiar smell, as well as stopping bleeding and restoring menstrual flow, has very good effects for different gynecologic inflammation diseases, and also can achieve the health effect of moisturizing and compacting the vagina.
Description
Technical field
The present invention relates to a kind of medicine and preparation method thereof, a kind of medicine for gynecological inflammation and preparation method thereof.
Background technology
Gynecological inflammation is the disease of female reproductive system, and cardinal symptom is based on leucorrhoea grow in quantity, and and itch pain uncomfortable with pudendum,
The traditional Chinese medical science claims leukorrheal diseases.The most common are vaginitis, cervicitis.
Normal healthy women vagina has nature defense function due to the feature of anatomical tissue to the intrusion of pathogen, such as closing of vaginal orifice
Closing, vagina front and rear wall is close to, vaginal epithelial cell hypertrophy under the influence of estrogen and cells of superficial layer keratinization, vagina acid-base degree
Keep balance, make the breeding of the pathogen of adaptation alkalescence be suppressed, and neck tube mucus is alkalescence, when the defence merit naturally of vagina
When can be destroyed, pathogen is prone to invade, and causes colpitis.
There are aerobe and anaerobe to reside in intravaginal under normal circumstances, form normal vaginal microbial flora.Any reason by vagina with
Ecological balance between flora is broken, it is possible to formation condition pathogenic bacterium.The most common have: bacterial vaginosis, monilial
Vaginitis, trichomonal vaginitis, senile vaginitis, infantile vaginitis.
Cervicitis is one of gynecological's common disease, including vaginal part of cervix inflammation and cervical canal mucosal inflammation.Because of cervical canal
Portio vaginalis squamous epithelial cancer continues mutually with vagina squamous, and colpitis all can cause vaginal part of cervix inflammation.Owing to cervical canal sticks
Film epithelium is simple columnar epithelium, and anti-infection ability is poor, easily infects.Clinical common cervicitis is Semen Impatientis cervix uteri
Pipe mucositis, if acute cervicitis is without timely diagnosis and treatment or pathogen sustainable existence, may result in chronic cervicitis disease.
Summary of the invention
The invention provides a kind of medicine for gynecological inflammation and preparation method thereof.
A kind of medicine for gynecological inflammation, it is characterised in that be made up of the raw material of following weight ratio: Borneolum Syntheticum 0.1~4 parts, Camphor tree
Red 0.3~5 part, Indigo Naturalis 0.2~10 parts, Pulvis Talci 1~15 parts, Alumen 0.3~15 parts, Radix Glycyrrhizae 1~17 parts, Cortex Phellodendri 2~
20 parts, Radix Scutellariae 1~10 parts, Flos Lonicerae 5~15 parts, Fructus Forsythiae 2~17 parts, the Radix Stemonae 1~10 parts, Radix Arnebiae (Radix Lithospermi) 1~15 parts are bitter
Join 2~17 parts;
Optimizing further, medicine is made up of the raw material of following weight ratio: Borneolum Syntheticum 1~3 parts, Plumbum preparatium 1~3 parts, Indigo Naturalis 3~7 parts,
Pulvis Talci 5~10 parts, Alumen 1~10 parts, Radix Glycyrrhizae 5~12 parts, Cortex Phellodendri 10~13 parts, Radix Scutellariae 3~7 parts, Flos Lonicerae 7~
12 parts, Fructus Forsythiae 7~12 parts, the Radix Stemonae 4~6 parts, Radix Arnebiae (Radix Lithospermi) 2~7 parts, Radix Sophorae Flavescentis 5~12 parts;
Borneolum Syntheticum described in medicine is the extracted crystallization being processed into of fresh stem and leaf of feverfew Herba Blumeae Balsamiferae;
Indigo Naturalis described in medicine, Radix Glycyrrhizae, Cortex Phellodendri, Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, the Radix Stemonae, Radix Arnebiae (Radix Lithospermi), Radix Sophorae Flavescentis are dry medical material;
The preparation of pill comprises the steps:
(1), each raw material is weighed;
(2) Borneolum Syntheticum that, step (1) weighed, Plumbum preparatium, Indigo Naturalis, Pulvis Talci, Alumen, Radix Glycyrrhizae powder process;
(3) the powder sterilization, by step (2) prepared, places standby;
(4) Cortex Phellodendri, Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, the Radix Stemonae, the Radix Arnebiae (Radix Lithospermi) that, step (1) are weighed, Radix Sophorae Flavescentis is cataclasm, cataclasm length
It is 5~10mm, with alcohol extraction, prepares extracting solution, then extracting solution is concentrated into containing crude drug 1~2g/ml;
(5) the medicinal residues water extraction, by step (4) produced, is 60~90 degree by the temperature of water extraction, prepares extracting solution, then will
Extracting solution is concentrated into containing crude drug 1~2g/ml;
(6), the concentrated solution mixing pill that powder step (3) prepared prepares with step (4) and (5);
(7) the pill parcel coat, by step (6) prepared, slowly dissolves so that discharging medicine;
(8) the pill coat, by step (7) prepared disposes silk thread, stays vagina outer for pulling out residual drug pill.
The method that sterilization described in step (3) uses is ultraviolet radiation disinfection;
The method that pill described in step (6) uses is water-bindered pill-making method or moulds pill method, also can add adjuvant, it is ensured that ball
Agent intensity, the most fugitive rotten;
In step (2), the fineness of powder process is 100~200 mesh;
In step (8), wire length is 20~40cm, uses silkworm silk or nylon cord, uses the sides such as compacting, colligation, stickup
Formula is fixed on pill, packs after sterilizing.
Water preparation preparation comprises the steps:
(1), each raw material is weighed;
(2) Plumbum preparatium that, by step (1) weighs, Indigo Naturalis, Alumen, Pulvis Talci mix dispersion respectively with water, place standby;
(3) Borneolum Syntheticum, by step (1) weighed adds Mentholum mixing, prepares mixed liquor;
(4) Radix Glycyrrhizae, Cortex Phellodendri, Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, the Radix Stemonae, the Radix Arnebiae (Radix Lithospermi) that, step (1) are weighed, Radix Sophorae Flavescentis is cataclasm, cataclasm
A length of 5~10mm, with water extraction, be 60~90 degree by the temperature of water extraction, prepare extracting solution, then by extracting solution concentrate
To containing crude drug 1~2g/ml, place standby;
(5) liquid mixing, by step (2), (3), (4) prepared, prepares mixed liquor;
(6), the mixed liquor that step (5) prepares is added water and is configured to, containing crude drug 0.1~1g/ml, obtain described water preparation.
The present invention has the effect of uniqueness to gynecological inflammation, can not only control inflammation from the cause of disease, has the effect of sterilization sterilizing, also
Can effectively alleviate the pudendal pruritus symptom that inflammation is brought, and there is moist and effect of the vagina that compacts.
Borneolum Syntheticum acrid in the mouth, hardship, be slightly cold, and delicate fragrance a surname dissipate, and has refreshment of having one's ideas straightened out, the effect for the treatment of carbuncle sore infantile malnutrition hemorrhoid, has moist vagina,
Strengthening the effect of comfort, selected Borneolum Syntheticum is Blumeae preparatum Tabellae (L-Borneol), for feverfew Herba Blumeae Balsamiferae Blumea balsami
The extracted crystallization being processed into of fresh stem and leaf of fera (L.) DC., is more easy to be absorbed and nontoxic.
Plumbum preparatium has another name called Plumbum preparatium, red powder, Zhu Fen, lead powder used in cosmetics, is to close refining with lead, sulfur, Sal Nitri etc. to form, has removing toxic substances, granulation promoting,
The effect of eliminating phlegm down to arrest convulsion, often joins Alumen external, is used for treating skin sore, eczema tinea scabies, aphtha of the mouth and tongue, suppurates in ear, female
Cloudy ulcer.
Indigo Naturalis has a heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, the effect of pathogenic fire purging arresting convulsion, and for maculae caused by violent heat pathogen, heat in blood tells nosebleed, chest pain hemoptysis,
Aphtha, mumps, sore throat, pediatric epilepsy scared, scorching effective for the endogenous toxin that gynecological inflammation is adjoint.
Pulvis Talci selects medicine-food grade talc powder, for native hydrous magnesium silicate, hydroaropic substance, in vain to pale white crystals powder,
Acid water insoluble, cold and alkali liquor, for pharmaceutical preparation being applied wide lubricant hold concurrently fluidizer antiplastering aid, its stable chemical nature,
Without toxicity, side effect, when this invention effect is and mixes raw material, play anti-stick effect, simultaneously work as lubricating vagina effect.
The Alumen selected in invention, for the crystallization of the processed refinement of mineral alunite, main chemical compositions is 12 hydration sulfur
Acid aluminum potassium, external can detoxify parasite killing, dampness removing to stop itchin, leukorrhagia pudendal pruritus, leukorrhagia is had good effect, has convergence simultaneously
Effect, has, to uterine prolapse, slack vagina, the effect of compacting.
Radix Glycyrrhizae is used for ulcer sores, laryngopharynx swelling and pain etc..Can be alone, for oral administration or external application, or compatibility application.Ulcer sores, often with
Flos Lonicerae, Fructus Forsythiae equivalent use, play the merit of heat-clearing and toxic substances removing, altogether such as Xian fang Huoming Yin.
Cortex Phellodendri nature and flavor: bitter, cold, have effect of heat-clearing and toxic substances removing, heat clearing and damp drying, cure mainly hygropyretic dysentery, have loose bowels, jaundice, dream
Something lost, stranguria with turbid discharge, leukorrhagia, hectic fever due to YIN-deficiency consumptive fever, night sweat;And aphtha of the mouth and tongue, conjunctival congestion and swelling pain, skin sore, skin eczema.
Radix Scutellariae bitter in the mouth, cold in nature, there are heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive.Cure mainly epidemic febrile disease, upper respiratory tract
The diseases such as infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle,
Closing for woman's blood, drenching dew hematochezia also has unique effects.
Flos Lonicerae is cold in nature, sweet in the mouth, enters lung, the heart, stomach warp, has heat-clearing and toxic substances removing, antiinflammatory, effect of qi-restoratives treatment wind, cures mainly swollen
Disease, epidemic febrile disease is completely descended to generate heat, the disease such as pyretic toxicity carbuncle and ulcer and tumor.Its for dizzy dizzy, xerostomia make thirsty, hyperhidrosis unhappiness, enteritis,
Bacillary dysentery, measles, pneumonia, encephalitis b, epidemic encephalitis, acute mastitis, septicemia, appendicitis, skin infection, carbuncle furuncle, pellet
The diseases such as poison, parotitis, suppurative tonsillitis all have certain curative effect, the normal and same use of Fructus Forsythiae, have heat-clearing and toxic substances removing, dispelling wind solution
Table effect.
Fructus Forsythiae nature and flavor: bitter, cool, there is heat clearing away, removing toxic substances, eliminating stagnation, the function of detumescence, cure mainly warm, erysipelas, macule, carbuncle
Infections toxic swelling, scrofula, urine stranguria with urinary obstruction, moreover it is possible to pain relieving, logical menstruation.
The Radix Stemonae have relieving cough and resolving phlegm, gentle lung qi, heat radiation induce sweat, the effect of parasite killing delousing, Radix Stemonae parasite killing and QI and blood is not lost,
Most useful for people, outward for diseases such as head louse, body louse, pinworm, pudendal pruritus, ascariasis, use same with Radix Sophorae Flavescentis, can removing dampness and detoxicating
Parasite killing, cures mainly monilial vaginitis.
Radix Arnebiae (Radix Lithospermi) function removing pathogenic heat from blood and toxic substance from the body, removing the necrotic tissue and promoting granulation.Cure mainly burn due to hot liquid or fire, the disease such as chilblain is festered, for a long time not closing in.Long with Radix Scutellariae,
The multi-flavor medicines such as Cortex Phellodendri, Radix Glycyrrhizae, Borneolum Syntheticum with the use of.
Radix Sophorae Flavescentis has heat clearing and damp drying, parasite killing, and effect of diuresis, for leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin
Pruritus, scabies leprosy, external treatment trichomonal vaginitis.
The present invention, for gynecological inflammation, can sterilize pest-resistant from source, and Alumen has bactericidal action widely, and the Radix Stemonae has treatment
Candidal vaginitis effect, Radix Sophorae Flavescentis has the effect for the treatment of trichomonal vaginitis;Radix Glycyrrhizae, Flos Lonicerae, Fructus Forsythiae then have heat clearing away solution
Poison, the effect of dispelling wind to relieve the exterior syndrome;Plumbum preparatium and Radix Arnebiae (Radix Lithospermi) energy putrefaction-removing granulation-promoting, fester for pudendum and have good effect;Borneolum Syntheticum has uniqueness
The effect of antalgesic-antipruritic, and there is delicate fragrance can go to eliminate the unusual smell;Alumen and Fructus Forsythiae also have the effect of hemostasis;Fructus Forsythiae and Radix Scutellariae are also
Menses Guan Bi the most freely there is effect very well;Cortex Phellodendri has effect of heat-clearing and toxic substances removing, heat clearing and damp drying, and leukorrheal diseases are had unique effects.
The present invention has sterilization pest-resistant, heat-clearing and toxic substances removing, putrefaction-removing granulation-promoting, antalgesic-antipruritic, the effect stimulated the menstrual flow of going to eliminate the unusual smell, stop blooding,
Inhomogeneous gynecological inflammation is had good effect, and the health-care effect of the moist vagina that compacts can also be played.
Detailed description of the invention
Being described principle and the feature of the present invention below in conjunction with embodiment, example is served only for explaining the present invention, not uses
In limiting the scope of the present invention.
Embodiment 1
Parts by weight of raw materials: Borneolum Syntheticum 2 parts, Plumbum preparatium 2 parts, Indigo Naturalis 5 parts, Pulvis Talci 7 parts, Alumen 7 parts, 7 parts of Radix Glycyrrhizae, yellow
Cypress 12 parts, Radix Scutellariae 5 parts, Flos Lonicerae 10 parts, Fructus Forsythiae 10 parts, the Radix Stemonae 5 parts, Radix Arnebiae (Radix Lithospermi) 5 parts, Radix Sophorae Flavescentis 8 parts;
Described Borneolum Syntheticum is the extracted crystallization being processed into of fresh stem and leaf of feverfew Herba Blumeae Balsamiferae.
Described Indigo Naturalis, Radix Glycyrrhizae, Cortex Phellodendri, Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, the Radix Stemonae, Radix Arnebiae (Radix Lithospermi), Radix Sophorae Flavescentis are dry medical material;
Prepared by pill:
(1), each raw material is weighed;
(2) Borneolum Syntheticum that, by step (1) weighs, Plumbum preparatium, Indigo Naturalis, Pulvis Talci, Alumen, Radix Glycyrrhizae powder process, the fineness of powder process is 200
Mesh;
(3), the powder that step (2) prepares is carried out ultraviolet radiation disinfection sterilizing, place standby;
(4) Cortex Phellodendri, Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, the Radix Stemonae, the Radix Arnebiae (Radix Lithospermi) that, step (1) are weighed, Radix Sophorae Flavescentis is cataclasm, cataclasm length
For 5mm, with alcohol extraction, prepare extracting solution, then extracting solution is concentrated into containing crude drug 2g/ml;
(5) the medicinal residues water extraction, by step (4) produced, is 90 degree by the temperature of water extraction, prepares extracting solution, then will extract
Liquid is concentrated into containing crude drug 2g/ml;
(6), the concentrated solution that powder step (3) prepared prepares with step (4) and (5) uses water-bindered pill-making method to mix pill;
(7) the pill parcel coat, step (6) prepared;
(8) the pill coat, by step (7) prepared disposes silk thread, and staying line length is 20cm.
Embodiment 2
Raw material prepares same as in Example 1, then prepares water preparation.
Water preparation preparation comprises the steps:
(1), each raw material is weighed;
(2) Plumbum preparatium that, by step (1) weighs, Indigo Naturalis, Alumen, Pulvis Talci mix dispersion respectively with water, place standby;
(3) Borneolum Syntheticum, by step (1) weighed adds Mentholum mixing, prepares mixed liquor;
(4) Radix Glycyrrhizae, Cortex Phellodendri, Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, the Radix Stemonae, the Radix Arnebiae (Radix Lithospermi) that, step (1) are weighed, Radix Sophorae Flavescentis is cataclasm, cataclasm
A length of 10mm, with water extraction, be 80 degree by the temperature of water extraction, prepare extracting solution, then extracting solution is concentrated into containing raw
Medicine 1g/ml, places standby;
(5) liquid mixing, by step (2), (3), (4) prepared, prepares mixed liquor;
(6), the mixed liquor that step (5) prepares is added water and is configured to, containing crude drug 1g/ml, obtain described water preparation.
Embodiment 3
Parts by weight of raw materials: Borneolum Syntheticum 1 part, Plumbum preparatium 1 part, Indigo Naturalis 4 parts, Pulvis Talci 10 parts, Alumen 10 parts, 5 parts of Radix Glycyrrhizae,
Cortex Phellodendri 10 parts, Radix Scutellariae 3 parts, Flos Lonicerae 12 parts, Fructus Forsythiae 12 parts, the Radix Stemonae 6 parts, Radix Arnebiae (Radix Lithospermi) 7 parts, Radix Sophorae Flavescentis 12 parts;
Described Borneolum Syntheticum is the extracted crystallization being processed into of fresh stem and leaf of feverfew Herba Blumeae Balsamiferae.
Described Indigo Naturalis, Radix Glycyrrhizae, Cortex Phellodendri, Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, the Radix Stemonae, Radix Arnebiae (Radix Lithospermi), Radix Sophorae Flavescentis are dry medical material;
Prepared by pill:
(1), each raw material is weighed;
(2) Borneolum Syntheticum that, by step (1) weighs, Plumbum preparatium, Indigo Naturalis, Pulvis Talci, Alumen, Radix Glycyrrhizae powder process, the fineness of powder process is 150
Mesh;
(3), the powder that step (2) prepares is carried out ultraviolet radiation disinfection sterilizing, place standby;
(4) Cortex Phellodendri, Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, the Radix Stemonae, the Radix Arnebiae (Radix Lithospermi) that, step (1) are weighed, Radix Sophorae Flavescentis is cataclasm, cataclasm length
For 7mm, with alcohol extraction, prepare extracting solution, then extracting solution is concentrated into containing crude drug 1g/ml;
(5) the medicinal residues water extraction, by step (4) produced, is 90 degree by the temperature of water extraction, prepares extracting solution, then will extract
Liquid is concentrated into containing crude drug 2g/ml;
(6), the concentrated solution that powder step (3) prepared prepares with step (4) and (5) uses water-bindered pill-making method to mix pill;
(7) the pill parcel coat, step (6) prepared;
(8) the pill coat, by step (7) prepared disposes silk thread, and staying line length is 25cm.
Embodiment 4
Raw material prepares same as in Example 3, then prepares water preparation.
Water preparation preparation comprises the steps:
(1), each raw material is weighed;
(2) Plumbum preparatium that, by step (1) weighs, Indigo Naturalis, Alumen, Pulvis Talci mix dispersion respectively with water, place standby;
(3) Borneolum Syntheticum, by step (1) weighed adds Mentholum mixing, prepares mixed liquor;
(4) Radix Glycyrrhizae, Cortex Phellodendri, Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, the Radix Stemonae, the Radix Arnebiae (Radix Lithospermi) that, step (1) are weighed, Radix Sophorae Flavescentis is cataclasm, cataclasm
A length of 6mm, with water extraction, be 60 degree by the temperature of water extraction, prepare extracting solution, then extracting solution is concentrated into containing crude drug
1.5g/ml, places standby;
(5) liquid mixing, by step (2), (3), (4) prepared, prepares mixed liquor;
(6), the mixed liquor that step (5) prepares is added water and is configured to, containing crude drug 0.6g/ml, obtain described water preparation.
Claims (10)
1. the medicine for gynecological inflammation, it is characterised in that be made up of the raw material of following weight ratio: Borneolum Syntheticum 0.1~4 parts,
Plumbum preparatium 0.3~5 parts, Indigo Naturalis 0.2~10 parts, Pulvis Talci 1~15 parts, Alumen 0.3~15 parts, Radix Glycyrrhizae 1~17 parts, Cortex Phellodendri
2~20 parts, Radix Scutellariae 1~10 parts, Flos Lonicerae 5~15 parts, Fructus Forsythiae 2~17 parts, the Radix Stemonae 1~10 parts, Radix Arnebiae (Radix Lithospermi) 1~15 parts,
Radix Sophorae Flavescentis 2~17 parts.
Medicine the most according to claim 1, it is characterised in that be made up of the raw material of following weight ratio: Borneolum Syntheticum 1~3 parts,
Plumbum preparatium 1~3 parts, Indigo Naturalis 3~7 parts, Pulvis Talci 5~10 parts, Alumen 1~10 parts, Radix Glycyrrhizae 5~12 parts, Cortex Phellodendri 10~13
Part, Radix Scutellariae 3~7 parts, Flos Lonicerae 7~12 parts, Fructus Forsythiae 7~12 parts, the Radix Stemonae 4~6 parts, Radix Arnebiae (Radix Lithospermi) 2~7 parts, Radix Sophorae Flavescentis 5~
12 parts.
Medicine the most according to claim 1, it is characterised in that described Borneolum Syntheticum is the fresh stem and leaf of feverfew Herba Blumeae Balsamiferae
The extracted crystallization being processed into.
Medicine the most according to claim 1, it is characterised in that described Indigo Naturalis, Radix Glycyrrhizae, Cortex Phellodendri, Radix Scutellariae, Flos Lonicerae,
Fructus Forsythiae, the Radix Stemonae, Radix Arnebiae (Radix Lithospermi), Radix Sophorae Flavescentis are dry medical material.
5. according to the preparation method of the medicine described in claim 1,2,3 or 4, it is characterised in that under the preparation of pill includes
State step:
(1), each raw material is weighed;
(2) Borneolum Syntheticum that, step (1) weighed, Plumbum preparatium, Indigo Naturalis, Pulvis Talci, Alumen, Radix Glycyrrhizae powder process;
(3) the powder sterilization, by step (2) prepared, places standby;
(4) Cortex Phellodendri, Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, the Radix Stemonae, the Radix Arnebiae (Radix Lithospermi) that, by step (1) weigh, Radix Sophorae Flavescentis is cataclasm, with alcohol extraction,
Prepare extracting solution, then extracting solution is concentrated into containing crude drug 1~2g/ml;
(5) the medicinal residues water extraction, by step (4) produced, prepares extracting solution, then is concentrated into by extracting solution containing crude drug 1~2g/ml;
(6), the concentrated solution mixing pill that powder step (3) prepared prepares with step (4) and (5);
(7) the pill parcel coat, step (6) prepared;
(8), the pill coat that step (7) prepares is disposed silk thread.
6. according to the preparation method of the medicine described in claim 1,2,3 or 4, it is characterised in that water preparation preparation includes following
Step:
(1), each raw material is weighed;
(2) Plumbum preparatium that, by step (1) weighs, Indigo Naturalis, Alumen, Pulvis Talci mix dispersion respectively with water, place standby;
(3) Borneolum Syntheticum, by step (1) weighed adds Mentholum mixing, prepares mixed liquor;
(4) Radix Glycyrrhizae, Cortex Phellodendri, Radix Scutellariae, Flos Lonicerae, Fructus Forsythiae, the Radix Stemonae, the Radix Arnebiae (Radix Lithospermi) that, step (1) are weighed, Radix Sophorae Flavescentis is cataclasm, uses water
Extract, prepare extracting solution, then extracting solution is concentrated into containing crude drug 1~2g/ml, place standby;
(5) liquid mixing, by step (2), (3), (4) prepared, prepares mixed liquor;
(6), the mixed liquor that step (5) prepares is added water and is configured to, containing crude drug 0.1~1g/ml, obtain described water preparation.
Preparation method the most according to claim 5, it is characterised in that the side that the sterilization described in step (3) uses
Method is ultraviolet radiation disinfection.
Preparation method the most according to claim 5, it is characterised in that the method that the pill described in step (6) uses is
Water-bindered pill-making method or mould pill method.
Preparation method the most according to claim 5, it is characterised in that in step (2), the fineness of powder process is 100~200
Mesh.
10. according to the preparation method described in claim 5 or 6, it is characterised in that described cataclasm a length of 5~10mm;
The temperature of described water extraction is 60~90 degree.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610321041.XA CN105943978A (en) | 2016-05-16 | 2016-05-16 | Medicine for treating gynecologic inflammation and preparation method of medicine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610321041.XA CN105943978A (en) | 2016-05-16 | 2016-05-16 | Medicine for treating gynecologic inflammation and preparation method of medicine |
Publications (1)
Publication Number | Publication Date |
---|---|
CN105943978A true CN105943978A (en) | 2016-09-21 |
Family
ID=56911884
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610321041.XA Pending CN105943978A (en) | 2016-05-16 | 2016-05-16 | Medicine for treating gynecologic inflammation and preparation method of medicine |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN105943978A (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101337040A (en) * | 2008-07-11 | 2009-01-07 | 丁绍余 | Gynecology lotion |
-
2016
- 2016-05-16 CN CN201610321041.XA patent/CN105943978A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101337040A (en) * | 2008-07-11 | 2009-01-07 | 丁绍余 | Gynecology lotion |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102160887B (en) | Medicament for treating gynecological inflammation and preparation method thereof | |
CN102895163B (en) | Natural green talcum powder | |
CN102145111B (en) | Traditional Chinese medicine composition for treating colpitis mycotica and preparation method thereof | |
CN102697961B (en) | Gynecological cleaning solution and preparation method thereof | |
CN101537107A (en) | External use liniment capable of treating dermatomycosis and preparation method thereof | |
CN103494958B (en) | Traditional Chinese medicine lotion for treating gynecological inflammations as well as preparation method thereof | |
CN102697857B (en) | Maternal towel liquid medicament for preventing puerperal infection and preparation method thereof | |
CN111991498B (en) | Heavy chain antibody composite gel for treating HPV and preparation method thereof | |
CN103301271B (en) | Tibetan medicine for treating pharyngitis and preparation method thereof | |
CN105727209A (en) | Traditional Chinese medicine composition for postpartum care | |
CN110393768A (en) | A kind of combined traditional Chinese medicine dabbling drug of Gilt Uterus anti-inflammatory and its preparation method and application | |
CN103071096B (en) | External preparation for treating senile vaginitis and preparation method of external preparation | |
CN103920073B (en) | A kind of chitosan reproductive tract biological antibiotic liquid and preparation method thereof | |
CN105998966A (en) | Drug for relieving vulval swelling and itching and preparing method thereof | |
CN105920462A (en) | Anti-inflammation and pain-relieving medicine acting on vagina and preparation method thereof | |
CN105943978A (en) | Medicine for treating gynecologic inflammation and preparation method of medicine | |
CN103028040B (en) | Traditional Chinese medicine composition for treating infantile chronic nasosinusitis and preparation method of traditional Chinese medicine composition | |
CN105998299A (en) | Detoxifying and dampness restraining medicine applied to gynecology and preparation method thereof | |
CN111743982A (en) | Vulva lotion and preparation method thereof | |
CN103768472A (en) | Suppository for treating gynecologic diseases and production method thereof | |
CN108853410A (en) | A kind of Chinese drugs agentia and its preparation method and application for preventing and treating gynecological disease | |
CN112294922A (en) | Chinese herbal medicine for treating vaginitis and preparation method thereof | |
CN104274617A (en) | Traditional Chinese medicine composition for nursing treatment of acute cervicitis | |
CN103599437A (en) | Traditional Chinese medicinal liquid for treatment of vaginitis | |
CN105920116A (en) | Medicine for treating impeded discharge of menses and preparation method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20160921 |
|
WD01 | Invention patent application deemed withdrawn after publication |