CN105943725A - Traditional Chinese medicine preparation for treating breast eczema and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for treating breast eczema and preparation method thereof Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/76—Salicaceae (Willow family), e.g. poplar
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention discloses a traditional Chinese medicine preparation for treating breast eczema and a preparation method thereof, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine preparation is prepared from folium eucalypti, jews marro, Polygonum caespitosum Bl., nauclea officinalis pierre ex petard, the root of fangji, golden cypress, Rubus ellipticus Smit, Entireleaf Neoalsomitra, willow roots, adenosma indianum, Polygonum aviculare, pollen pini, Hemigraphis procumbens (Lour.) Merr., Herb of Knottedflower Phyla, red fruit fig-tree leaves and bitter herbs. All the selected medicines are suitably compatible, the traditional Chinese medicine preparation conforms to the traditional Chinese medicine and modern medicine theory, the effects of clearing away heat and toxic materials, relieving itching and pain, achieving sterilization and antiphlogosis are achieved, use is convenient, the absorption effect is good, no poor or toxic or side effect exists, clinical verification shows that the good relief and treatment effect on breast eczema is achieved, and the traditional Chinese medicine preparation is suitable for being applied and popularized in clinical treatment and nursing of breast eczema.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation for treating breast eczema and preparation method.
Background technology
Breast eczema is apt to occur in nipple, mammary areola and about, and boundary understands, skin lesion is brownish red, rotten to the corn substantially, coated with
Squama or thin crust, can chap when having infiltration, and conscious pruritus has pain concurrently, is divided into acute eczema, subacute eczema with chronic
Eczema, is more common in nursing women.
1. acute eczema
Erythra is little pimple, papulovesicle or the phlysis that most intensive foxtail millet grain is big, substrate flushing.Owing to scratching, skin lesion
Can ooze out in obvious point-like and little rotten to the corn face, pathological changes center is the most heavier, and gradually spreads as surrounding, and periphery is dispersed in again mound
Rash, papulovesicle, therefore indefinite border.When being associated with infection, then inflammation can become apparent from, and forms pustule, and pus oozes out or ties Huang
Green or dirty brown crust.Also can merge folliculitis, furuncle, regional nodes's inflammation etc..
2. subacute eczema
After acute eczema inflammation alleviates, or acute stage, does not the most suitably process, and stalls for time and occurs sub-anxious relatively for a long time
Property eczema.Skin lesion based on little pimple, squama and incrustation, only minority papulovesicle or phlysis and erosion, also can have slight leaching
Profit, conscious still have violent pruritus.
3. chronic eczema
How form because of the differentiation of not healing of acute, subacute eczema recurrent exerbation, also can start i.e. to present chronic inflammatory disease.Affected part skin
Skin infiltration thickens, and becomes kermesinus and pigmentation, rough surface, coated with a little pityrosporum sample squama, or forms a scab because scratching, individual
Not having lichenification in various degree, have limitation, edge is the clearest, and periphery also can have pimple, papulovesicle to be dispersed in, when acute
Obvious sepage can be had during outbreak.Subjective symptoms also has obvious pruritus, often in paroxysm.The course of disease is indefinite, easily recurs, and prolonged does not heals.
The most acute, subacute, the equal course of disease of chronic eczema is indefinite, easily the most repeatedly, can phase transformation mutually, prolonged do not heal.Conscious scabies
Itch acutely.Drink, scratch, suds, hot water scald etc. all can make skin lesion increase the weight of, and gargalesthesia increases, and severe one can affect sleep, does not allows little
Look.
Be currently used for treat breast eczema medicament categories various, as Loratadine, intravenous drip 5% calcium bromide,
10% calcium gluconate, 10% hypo solution etc., but quickly recur after this kind of drug deactivated, prolonged application easily causes perhaps
Many untoward reaction.And Chinese materia medica is as the traditional medicine of China, there is the advantages such as effect strong, instant effect, lasting medicine, and do not have
Dependency, drug resistance and toxic and side effects, therefore select a kind of Chinese medicine preparation treatment breast eczema, will have for breast eczema
Highly important clinical meaning.
Summary of the invention
The invention provides a kind of Chinese medicine preparation for treating breast eczema and preparation method, Chinese medicine preparation institute of the present invention
Select medical material compatibility suitable, meet Chinese medicine and modern medicine is theoretical, there is heat-clearing and toxic substances removing, antipruritic pain relieving, effect of bactericidal antiphlogistic,
Easy to use, good absorbing effect, without bad and toxic and side effects, according to clinical verification, breast eczema is had fabulous alleviation and treatment
Effect, is suitable to clinical treatment and the nursing popularization and application of breast eczema.
For achieving the above object, technical scheme is implemented as follows:
A kind of Chinese medicine preparation for treating breast eczema, makes raw material composition and the weight of described Chinese medicine preparation effective ingredient
Amount number is:
Make described Chinese medicine preparation effective ingredient raw material composition and parts by weight be:
Make described Chinese medicine preparation effective ingredient raw material composition and parts by weight be:
Make described Chinese medicine preparation effective ingredient raw material composition and parts by weight be:
The preparation method of a kind of Chinese medicine preparation for treating breast eczema, comprises the following steps that:
(1) Folium eucalypti globueli (Eucalyptus globulus Labill.), Flos kerriae japonicae and attached column having been spent the removal of impurity, cleaned, put in container, the micro-stir-fry of little fire to tack-free is
Can, taking-up is dried in the air cool, grinds into powder, obtained the fine powder of 140 mesh in being placed in mortar, standby；
(2) Herba Polygoni caespitosi, Lignum et Radix Naucleae, Radix Stephaniae Tetrandrae, Cortex Phellodendri, Neoalsomitra integrifoliola (Cogn.) Hucth., Radix Salicis Babylonicae and Pollen Pini are gone the removal of impurity, clean, put into container
In, add 6 times amount distilled water, soak 2～3 hours, then add 5 times amount distilled water, decoct 2 hours, extract decoction liquor；Add
3 times amount distilled water, decoct 1.5 hours, extract decoction liquor, finally merge the decoction liquor extracted 2 times, filter, obtain filtrate, be condensed into
At 60 DEG C, relative density is the thick paste of 1.10～1.13, standby；
(3) Huang leaf, Folium fici wightianae (Ficus wightiana Wall) and Herba Sonchi Oleracei are gone the removal of impurity, clean, dry, grind into powder in being placed in mortar, obtained 160 mesh
Fine powder, standby；
(4) Herba Adenosmae Glutinosi, Herba Polygoni Avicularis and Herba phylae nodieflorae are gone the removal of impurity, clean, put into and container is smash juice, filter, obtain filtrate, concentrate
At becoming 60 DEG C, relative density is the thick paste of 1.10～1.13, standby；
(5) medicine is made after step (1), the fine powder of step (3) gained being mixed with the thick paste of step (2), step (4) gained
Cream, is the Chinese medicine preparation for treating breast eczema of the present invention.
The property of medicine of Chinese medicine used by the present invention is as follows:
Folium eucalypti globueli (Eucalyptus globulus Labill.): bitter in the mouth, pungent, cool in nature；Return lung, stomach, spleen, Liver Channel.Dispelling wind to relieve the exterior syndrome, heat-clearing and toxic substances removing, phlegm-eliminiating and qi-regulating, parasite killing is only
Itch.For catching a cold, high dyspnea of heat type is coughed, pertussis, abdominal distention, dysentery of suffering from diarrhoea, rheumatalgia, breast eczema, scabies, burn and scald." see
For Practical Chinese medicinal " carry: " antipyretic, control enteritis and bladder illness.”
Flos kerriae japonicae: bitter in the mouth, puckery, property is put down；Return lung, stomach, spleen channel.Preventing phlegm from forming and stopping coughing, inducing diuresis to remove edema, removing toxic substances.For coughing, rheumatism
Arthralgia pain, puerperal impairment caused by overstrain pain, edema, dysuria, dyspepsia, swollen ulcer drug, eczema, urticaria." Traditional Chinese Medicine in Sichuan will " carries:
" control chronic cough, dyspepsia；Washout children's's urticaria.”
Herba Polygoni caespitosi: acrid in the mouth, property is put down.Heat clearing and damp drying, spleen invigorating disappears infantile malnutrition, promoting blood flow to regulate menstruation, removing toxic substances and promoting subsidence of swelling.For dysentery, infantile malnutrition
Disease, menoxenia, eczema tinea pedis, venom.
Lignum et Radix Naucleae: bitter in the mouth, cold in nature.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain.For cold, fever, acute tonsillitis, pharyngolaryngitis, prop up
Tracheitis, pneumonia, urinary system infection, enteritis and dysentery, cholecystitis, mastitis, carbuncle furuncle abscess." conventional Chinese herbal medicine handbook " carries: " clear
Thermal detoxification, reducing swelling and alleviating pain.Treating acute tonsillitis, pharyngolaryngitis, mastitis, enteritis, bacillary dysentery, urinary tract infection, cholecystitis, lower limb are burst
Infections, tinea pedis infects, furuncle and phyma pus infections, dermatitis and eczema.”
Radix Stephaniae Tetrandrae: bitter in the mouth, cold in nature；Return bladder, lung meridian.Inducing diuresis to remove edema, wind-expelling pain-stopping.For edema tinea pedis, dysuria is wet
Rash sore, rheumatic arthralgia, hypertension." property of medicine is fallen " carries: " controlling wet wind facial palsy, brothers ache, and dissipate and stay expectorant, main lung qi to cough and breathe heavily.Wood
Radix Stephaniae Tetrandrae: control in man's podomere pathogenic wind toxic wind in silence, main eliminating stagnation gas carbuncle, pyrexial malaria, edema caused by wind, control bladder.”
Cortex Phellodendri: bitter in the mouth, cold in nature；Return kidney, bladder warp.Heat clearing and damp drying, pathogenic fire purging is except steaming, detoxification sore treatment.For damp-heat dysentery, yellow
Subcutaneous ulcer leukorrhagia, pyretic stranguria tinea pedis, hectic fever due to YIN-deficiency consumptive fever, night sweat seminal emission, sore swollen toxin, eczema pruritus." Japan hanako materia medica " carries: " feel at ease except labor,
Control hectic fever due to YIN-deficiency, wash liver, improving eyesight, many tears, xerostomia, heat in the heart, kill infantile malnutrition worm, control ascarid pained, scabies, processed with honey controls serious epistaxis, hemorrhoidal hamorrhage, rushes down blood, after
Anxious heat is divided to swell and ache.”
Huang Ye: salty in the mouth, acid, property is put down；GUIXIN, lung meridian.Removing toxic substances parasite killing, removing dampness is antipruritic.For eczema pruritus, impetigo,
Traumatic hemorrhage, burn and scald.
Neoalsomitra integrifoliola (Cogn.) Hucth.: bitter in the mouth, puckery, cold in nature.Heat-clearing and toxic substances removing, anti-inflammation and sterilization, restrain pain relieving.For bacillary dysentery, acute gastroenteritis, stomach
And duodenal ulcer, abdominal pain, diarrhoea, urinary tract infection, high heat, pharyngolaryngitis, tonsillitis, have blood in stool, neurasthenia.
Radix Salicis Babylonicae: bitter in the mouth, cold in nature；GUIXIN warp.Relieving stranguria by diuresis, expelling wind and removing dampness.For gonorrhea nebulousurine, edema jaundice, arthritis pain
Bitterly, yellow fluid eczema, toothache is scalded." experiment of TCM research " carries: " water eczema of harnessing the Yellow River, hemorrhoid, itch in stranguria with turbid discharge stem.”
Herba Adenosmae Glutinosi: acrid in the mouth, hardship, warm in nature；Attach to the lung and stomach meridians.Wind-damp dispelling, detumescence poison, circulation of qi promoting eliminating stasis to stop pain.For rheumatic bone
Bitterly, abdominal pain due to stagnation of QI, furuncle toxic swelling, skin eczema, pruritus, traumatic injury." conventional Chinese herbal medicine handbook " carries: " wind-damp dispelling, detumescence
Bitterly.Controlling poliomyelitis, rheumatic ostalgia, wind and cold is suffered from abdominal pain, venom, traumatic injury, furuncle toxic swelling.”
Herba Polygoni Avicularis: bitter in the mouth, cold nature；Return bladder warp.Diuresis, heat clearing away, parasite killing.For the pyretic stranguria difficulty in urination, the jaundice erosion of the vulva, leucorrhea ascarid
Worm, infantile malnutrition hemorrhoid swell, eczema." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " diuresis.Control five types of stranguria nebulousurine, pyretic stranguria, the stasis of blood puckery key that closes the border of essence, and control married woman's gas
Strongly fragrant, damp and hot in stomach, or the disease of leucorrhea.”
Pollen Pini: sweet in the mouth, warm in nature；Return liver, spleen channel.Dispeling the wind QI invigorating, removing dampness stops blooding.Revolving dizziness for head, middle void has a stomach-ache, for a long time
Dysentery, all skin ulcers are wet rotten, wound hemorrhage." Traditional Chinese Medicine in Sichuan will " carries: " astringing to arrest bleeding.Controlling skin eczema, impetigo is wet rotten not to form a scab.”
Attached column flower: taste is micro-pungent, cool in nature.Heat-clearing and toxic substances removing, dampness removing is antipruritic, reducing swelling and alleviating pain.For dysentery skin infection, eczema, skin
Pruritus, caterpillar stabs, traumatic injury.
Herba phylae nodieflorae: mildly bitter flavor, cool in nature；Return lung, the heart, small intestine meridian.Heat-clearing and toxic substances removing.For laryngopharynx swelling and pain, ulcerative gingivitis is had loose bowels, dysentery
Disease, skin sore, herpes zoster, eczema scabies." Quanzhou book on Chinese herbal medicine " carries: " heat clearing away, dispels the wind, removing toxic substances.Control swollen ulcer drug, swelling throat
Bitterly, hematodiarrhoea, mad dog such as is bitten at the card.”
Folium fici wightianae (Ficus wightiana Wall): sweet in the mouth, micro-hardship, property is put down.Heat-clearing and toxic substances removing, removing damp to relieve itching.For painting allergy, eczema, thrush." Fujian
Traditional herbal medicine " carry: " antipyretic circulation of qi promoting, dehumidify the rash that disappears.”
Herba Sonchi Oleracei: bitter in the mouth, cold in nature；GUIXIN, stomach, large intestine channel.Heat-clearing and toxic substances removing, removing blood stasis with potent drugs invigorates blood circulation, evacuation of pus.For appendicitis, abdominal cavity
Abscess, enteritis and dysentery, acute and chronic pelvic inflammatory disease, cough due to lung-heat, pulmonary tuberculosis, hematemesis and epistaxis, traumatic injury, eczema scrotum.
The present invention compared with prior art, has the advantages that
Selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meets Chinese medicine and modern medicine theoretical, have heat-clearing and toxic substances removing,
Antipruritic pain relieving, effect of bactericidal antiphlogistic, easy to use, good absorbing effect, without bad and toxic and side effects, according to clinical verification, to breast
Room eczema has fabulous alleviation and therapeutic effect, is suitable to clinical treatment and the nursing popularization and application of breast eczema.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The processing step of Chinese medicine preparation preparation method of the present invention is:
(1) Folium eucalypti globueli (Eucalyptus globulus Labill.), Flos kerriae japonicae and attached column having been spent the removal of impurity, cleaned, put in container, the micro-stir-fry of little fire to tack-free is
Can, taking-up is dried in the air cool, grinds into powder, obtained the fine powder of 140 mesh in being placed in mortar, standby；
(2) Herba Polygoni caespitosi, Lignum et Radix Naucleae, Radix Stephaniae Tetrandrae, Cortex Phellodendri, Neoalsomitra integrifoliola (Cogn.) Hucth., Radix Salicis Babylonicae and Pollen Pini are gone the removal of impurity, clean, put into container
In, add 6 times amount distilled water, soak 2～3 hours, then add 5 times amount distilled water, decoct 2 hours, extract decoction liquor；Add
3 times amount distilled water, decoct 1.5 hours, extract decoction liquor, finally merge the decoction liquor extracted 2 times, filter, obtain filtrate, be condensed into
At 60 DEG C, relative density is the thick paste of 1.10～1.13, standby；
(3) Huang leaf, Folium fici wightianae (Ficus wightiana Wall) and Herba Sonchi Oleracei are gone the removal of impurity, clean, dry, grind into powder in being placed in mortar, obtained 160 mesh
Fine powder, standby；
(4) Herba Adenosmae Glutinosi, Herba Polygoni Avicularis and Herba phylae nodieflorae are gone the removal of impurity, clean, put into and container is smash juice, filter, obtain filtrate, concentrate
At becoming 60 DEG C, relative density is the thick paste of 1.10～1.13, standby；
(5) medicine is made after step (1), the fine powder of step (3) gained being mixed with the thick paste of step (2), step (4) gained
Cream, is the Chinese medicine preparation for treating breast eczema of the present invention.
Usage and dosage: external, every day 1～2 times, each 1.5～2ml, uniform application, at breast eczema skin, 3 days is
One course for the treatment of, usual 1～3 course for the treatment of of recovery from illness.
Embodiment 2
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 3
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 4
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage are same as in Example 1.
Clinical data:
1, case selection:
Selecting the breast eczema patient 350 example clinical observation that my institute or outer court make a definite diagnosis, patient is randomly divided into two groups, treatment group
175 examples, age 21～35 years old, 28 years old mean age, the course of disease 10 days～1 month, average 20 days.Matched group 175 example, the age 20～
34 years old, 27 years old mean age, the course of disease 7 days～1 month, average 18 days.The course of disease of two groups of cases, degrees of symptoms basic one
Cause, without significant difference, there is comparability.
2, medicament selection:
Treatment group patient uses Chinese medicine preparation of the present invention, external, every day 1～2 times, each 1.5～2ml, uniform application in
At breast eczema skin, within 3 days, it is a course for the treatment of, usual 1～3 course for the treatment of of recovery from illness.
Matched group patient uses Halometasone Cream, is applied to affected part with thin layer, according to symptom every day 1～2 times, and rubs lenitively
Wipe.
3, efficacy determination:
(1) cure: the transference cures such as breast itching, papulovesicle, vesicle are rotten to the corn；Getting well, health is fully recovered.
(2) effective: above-mentioned symptom has been alleviated.
(3) invalid: above-mentioned symptom is unchanged.
4, result:
Use in the treatment group of medicine of the present invention, cure 130 examples, effective 32 examples, invalid 13 examples, cure rate 74.3%, always
Effective percentage 92.6%.
Matched group is cured 96 examples, effective 36 examples, invalid 43 examples, cure rate 54.9%, total effective rate 75.4%.
Result above shows, treatment group cure rate and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, ×× slowly, female, 22 years old, civilian, Zhejiang Hangzhou people.Patient's nipple, mammary areola and about, skin lesion is brownish red,
Rotten to the corn substantially, coated with squama, be diagnosed as breast eczema by my institute.After using 1 course for the treatment of of Chinese medicine preparation of the present invention, symptom is obvious
Alleviating, be continuing with 1 course for the treatment of, symptom all disappears.Follow up a case by regular visits to not recur so far.
2, grandson's ××, female, 25 years old, unemployed, people from Sichuan.Patient suffers from breast eczema, and erythra is most intensive
The little pimple that foxtail millet grain is big, substrate flushing, owing to scratching, skin lesion is that obvious point-like is oozed out and little rotten to the corn face, and pathological changes center is the most relatively
Weight, and gradually spread as surrounding.Using multi-medicament, effect is the best.After using 1 course for the treatment of of Chinese medicine preparation of the present invention, body
Body gradually rehabilitation, symptom is substantially alleviated, and is continuing with 1 course for the treatment of, above transference cure.Follow up a case by regular visits to not recur so far.
3, Yuan's ××, female, 29 years old, Enterprise Staff, people from Wuhan, Hubei.Little pimple, squama and incrustation is had at patient's chest, acute
Strong pruritus.After using 2 courses for the treatment of of Chinese medicine preparation of the present invention, symptom is clearly better, and after being continuing with 1 course for the treatment of, pruritus disappears, breast
Room eczema is removed.Follow up a case by regular visits to not recur so far.
4, old ××, female, 30 years old, company clerk, Zhengzhou, henan people.At patient's chest, skin infiltration thickens, and becomes dark red
Color, pigmentation, rough surface, scratch and form a scab, be diagnosed as chronic breast eczema by my institute.Use medicine of the present invention 1 treatment
Journey, no longer pruritus at breast eczema, be continuing with 2 the course for the treatment of rear udder attachment skin recover normal.Follow up a case by regular visits to not recur so far.
5, Xue's ××, female, 33 years old, sales promotion person, people from Hanzhong.Patient suffers from breast eczema, recurrent exerbation, prolonged not
More, conscious acute pruritus.Once multi-medicament, poor effect were used.After using 2 courses for the treatment of of Chinese medicine preparation of the present invention, above disease
Shape takes a turn for the better, and after being continuing with 1 course for the treatment of, above transference cure, breast is fully recovered.Follow up a case by regular visits to not recur so far.
6, merchant's ××, female, 35 years old, accounting, people from Lanzhou, Gansu.Patient suffers from breast eczema, acute pruritus, therefore uses suds
Cleaning, even more serious, gargalesthesia increases, and has a strong impact on sleep.After using 1 course for the treatment of of Chinese medicine preparation of the present invention, symptom takes a turn for the better, and continues
And after using 1 course for the treatment of, breast recovers normal.Follow up a case by regular visits to not recur so far.
Claims (5)
1. the Chinese medicine preparation being used for treating breast eczema, it is characterised in that: make the former of described Chinese medicine preparation effective ingredient
Material forms and parts by weight are:
Folium eucalypti globueli (Eucalyptus globulus Labill.) 58～88 parts of Flos kerriae japonicaes 55～85 parts of Herba Polygoni caespitosis 53～83 portions of Lignum et Radix Naucleae 51～81 parts
Radix Stephaniae Tetrandrae 48～43～73 parts of yellow leaves 40 of 78 portions of Cortex Phellodendris～70 parts of Neoalsomitra integrifoliola (Cogn.) Hucth.s 38～68 parts
Radix Salicis Babylonicae 36～66 parts of Herba Adenosmae Glutinosis 33～63 parts of Herba Polygoni Avicularis 31～61 parts of Pollen Pinis 29～59 parts
Attached column spends 28～58 parts of Herba phylae nodiefloraes 24～54 parts of Folium fici wightianae (Ficus wightiana Wall)s 23～53 parts of Herba Sonchi Oleracei 18～48 parts.
A kind of Chinese medicine preparation for treating breast eczema the most according to claim 1, it is characterised in that: make described in
The raw material of medicine preparation effective ingredient forms and parts by weight are:
81 parts of Flos kerriae japonicaes of Folium eucalypti globueli (Eucalyptus globulus Labill.), 76 portions of Lignum et Radix Naucleae of 78 parts of Herba Polygoni caespitosis 74 parts
71 portions of Cortex Phellodendris of Radix Stephaniae Tetrandrae, 64 parts of Neoalsomitra integrifoliola (Cogn.) Hucth.s of 66 parts of yellow leaves 62 parts
60 parts of Herba Adenosmae Glutinosis of Radix Salicis Babylonicae, 54 parts of Pollen Pinis of 56 parts of Herba Polygoni Avicularis 52 parts
Attached column spends 51 parts of Herba phylae nodiefloraes, 46 parts of Herba Sonchi Oleracei of 47 parts of Folium fici wightianae (Ficus wightiana Wall)s 41 parts.
A kind of Chinese medicine preparation for treating breast eczema the most according to claim 1, it is characterised in that: make described in
The raw material of medicine preparation effective ingredient forms and parts by weight are:
74 parts of Flos kerriae japonicaes of Folium eucalypti globueli (Eucalyptus globulus Labill.), 69 portions of Lignum et Radix Naucleae of 71 parts of Herba Polygoni caespitosis 67 parts
64 portions of Cortex Phellodendris of Radix Stephaniae Tetrandrae, 57 parts of Neoalsomitra integrifoliola (Cogn.) Hucth.s of 59 parts of yellow leaves 54 parts
53 parts of Herba Adenosmae Glutinosis of Radix Salicis Babylonicae, 47 parts of Pollen Pinis of 49 parts of Herba Polygoni Avicularis 45 parts
Attached column spends 44 parts of Herba phylae nodiefloraes, 39 parts of Herba Sonchi Oleracei of 40 parts of Folium fici wightianae (Ficus wightiana Wall)s 34 parts.
A kind of Chinese medicine preparation for treating breast eczema the most according to claim 1, it is characterised in that: make described in
The raw material of medicine preparation effective ingredient forms and parts by weight are:
66 parts of Flos kerriae japonicaes of Folium eucalypti globueli (Eucalyptus globulus Labill.), 61 portions of Lignum et Radix Naucleae of 62 parts of Herba Polygoni caespitosis 60 parts
56 portions of Cortex Phellodendris of Radix Stephaniae Tetrandrae, 48 parts of Neoalsomitra integrifoliola (Cogn.) Hucth.s of 51 parts of yellow leaves 47 parts
42 parts of Herba Adenosmae Glutinosis of Radix Salicis Babylonicae, 40 parts of Pollen Pinis of 41 parts of Herba Polygoni Avicularis 37 parts
Attached column spends 36 parts of Herba phylae nodiefloraes, 31 parts of Herba Sonchi Oleracei of 32 parts of Folium fici wightianae (Ficus wightiana Wall)s 26 parts.
5. a preparation method for the Chinese medicine preparation for treating breast eczema as described in any one of Claims 1 to 4, it is special
Levy and be: comprise the following steps that:
(1) Folium eucalypti globueli (Eucalyptus globulus Labill.), Flos kerriae japonicae and attached column having been spent the removal of impurity, cleaned, put in container, the micro-stir-fry of little fire, to tack-free, takes
Go out to dry in the air cool, grind into powder in being placed in mortar, obtained the fine powder of 140 mesh, standby；
(2) Herba Polygoni caespitosi, Lignum et Radix Naucleae, Radix Stephaniae Tetrandrae, Cortex Phellodendri, Neoalsomitra integrifoliola (Cogn.) Hucth., Radix Salicis Babylonicae and Pollen Pini are gone the removal of impurity, clean, put in container, add
Enter 6 times amount distilled water, soak 2～3 hours, then add 5 times amount distilled water, decoct 2 hours, extract decoction liquor；Add 3 times amount
Distilled water, decocts 1.5 hours, extracts decoction liquor, finally merges the decoction liquor extracted 2 times, filter, obtain filtrate, be condensed into 60 DEG C
Lower relative density is the thick paste of 1.10～1.13, standby；
(3) Huang leaf, Folium fici wightianae (Ficus wightiana Wall) and Herba Sonchi Oleracei are gone the removal of impurity, clean, dry, grind into powder in being placed in mortar, obtained 160 purposes thin
Powder, standby；
(4) Herba Adenosmae Glutinosi, Herba Polygoni Avicularis and Herba phylae nodieflorae are gone the removal of impurity, clean, put into and container is smash juice, filter, obtain filtrate, be condensed into 60
At DEG C, relative density is the thick paste of 1.10～1.13, standby；
(5) ointment is made after step (1), the fine powder of step (3) gained being mixed with the thick paste of step (2), step (4) gained,
It is the described Chinese medicine preparation for treating breast eczema.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101129644A (en) * | 2007-09-24 | 2008-02-27 | 北京艺信堂医药研究所 | Traditional Chinese medicine formulated product for treating breast salt rheum |
| CN105663937A (en) * | 2016-04-06 | 2016-06-15 | 杨彩云 | Traditional Chinese medicine preparation for treating breast eczema and preparation method thereof |
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2016
- 2016-07-24 CN CN201610587296.0A patent/CN105943725A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101129644A (en) * | 2007-09-24 | 2008-02-27 | 北京艺信堂医药研究所 | Traditional Chinese medicine formulated product for treating breast salt rheum |
| CN105663937A (en) * | 2016-04-06 | 2016-06-15 | 杨彩云 | Traditional Chinese medicine preparation for treating breast eczema and preparation method thereof |
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