CN105942517A - Anxiety-improving health-care food and preparing method thereof - Google Patents
Anxiety-improving health-care food and preparing method thereof Download PDFInfo
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- CN105942517A CN105942517A CN201610558437.6A CN201610558437A CN105942517A CN 105942517 A CN105942517 A CN 105942517A CN 201610558437 A CN201610558437 A CN 201610558437A CN 105942517 A CN105942517 A CN 105942517A
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- 208000019901 Anxiety disease Diseases 0.000 title claims abstract description 35
- 235000013305 food Nutrition 0.000 title claims abstract description 7
- 238000000034 method Methods 0.000 title abstract description 3
- 230000036506 anxiety Effects 0.000 claims abstract description 26
- 240000001432 Calendula officinalis Species 0.000 claims abstract description 13
- 235000005881 Calendula officinalis Nutrition 0.000 claims abstract description 13
- 235000003724 spirulina extract Nutrition 0.000 claims abstract description 10
- 235000013402 health food Nutrition 0.000 claims description 23
- 238000003815 supercritical carbon dioxide extraction Methods 0.000 claims description 22
- 239000000203 mixture Substances 0.000 claims description 20
- 238000000605 extraction Methods 0.000 claims description 18
- 238000010298 pulverizing process Methods 0.000 claims description 14
- 238000000926 separation method Methods 0.000 claims description 14
- 238000010025 steaming Methods 0.000 claims description 13
- 241000756943 Codonopsis Species 0.000 claims description 12
- 238000002360 preparation method Methods 0.000 claims description 10
- UAJTZZNRJCKXJN-UHFFFAOYSA-M sodium;2-dodecoxy-2-oxoethanesulfonate Chemical compound [Na+].CCCCCCCCCCCCOC(=O)CS([O-])(=O)=O UAJTZZNRJCKXJN-UHFFFAOYSA-M 0.000 claims description 9
- 240000002900 Arthrospira platensis Species 0.000 claims description 7
- 235000016425 Arthrospira platensis Nutrition 0.000 claims description 7
- 229940082787 spirulina Drugs 0.000 claims description 7
- 238000009835 boiling Methods 0.000 claims description 6
- 238000007738 vacuum evaporation Methods 0.000 claims description 6
- 239000002775 capsule Substances 0.000 claims description 5
- 238000001035 drying Methods 0.000 claims description 5
- 238000000265 homogenisation Methods 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 238000004806 packaging method and process Methods 0.000 claims description 5
- 230000001954 sterilising effect Effects 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 239000000843 powder Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 5
- 238000002474 experimental method Methods 0.000 abstract description 4
- 244000189799 Asimina triloba Species 0.000 abstract 1
- 235000006264 Asimina triloba Nutrition 0.000 abstract 1
- 235000009467 Carica papaya Nutrition 0.000 abstract 1
- 244000037364 Cinnamomum aromaticum Species 0.000 abstract 1
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 abstract 1
- 241000007126 Codonopsis pilosula Species 0.000 abstract 1
- 241001289529 Fallopia multiflora Species 0.000 abstract 1
- 235000013717 Houttuynia Nutrition 0.000 abstract 1
- 240000000691 Houttuynia cordata Species 0.000 abstract 1
- 244000084767 Potentilla indica Species 0.000 abstract 1
- 241000220286 Sedum Species 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 230000000050 nutritive effect Effects 0.000 abstract 1
- 229940095110 selaginella tamariscina extract Drugs 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 9
- 241000699670 Mus sp. Species 0.000 description 5
- 229960004424 carbon dioxide Drugs 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 5
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 4
- 229910002092 carbon dioxide Inorganic materials 0.000 description 4
- 239000001569 carbon dioxide Substances 0.000 description 4
- 241000251468 Actinopterygii Species 0.000 description 3
- 244000025254 Cannabis sativa Species 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 3
- 229910052799 carbon Inorganic materials 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 235000020995 raw meat Nutrition 0.000 description 3
- 241000699666 Mus <mouse, genus> Species 0.000 description 2
- WEQAYVWKMWHEJO-UHFFFAOYSA-N chlormezanone Chemical compound O=S1(=O)CCC(=O)N(C)C1C1=CC=C(Cl)C=C1 WEQAYVWKMWHEJO-UHFFFAOYSA-N 0.000 description 2
- 229960002810 chlormezanone Drugs 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 206010025482 malaise Diseases 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 239000013641 positive control Substances 0.000 description 2
- 239000004408 titanium dioxide Substances 0.000 description 2
- 241000195493 Cryptophyta Species 0.000 description 1
- 241000790917 Dioxys <bee> Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000028017 Psychotic disease Diseases 0.000 description 1
- 229940125713 antianxiety drug Drugs 0.000 description 1
- 230000006400 anxiety behaviour Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 235000021028 berry Nutrition 0.000 description 1
- 229910002090 carbon oxide Inorganic materials 0.000 description 1
- 230000027288 circadian rhythm Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 235000008935 nutritious Nutrition 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000007086 side reaction Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/748—Cyanobacteria, i.e. blue-green bacteria or blue-green algae, e.g. spirulina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/41—Crassulaceae (Stonecrop family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/732—Chaenomeles, e.g. flowering quince
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention discloses anxiety-improving health-care food and a preparing method thereof. The anxiety-improving health-care food comprises, by weight, 20-30 parts of radix achyranthis bidentatae, 12-20 parts of dragon bones, 10-15 parts of codonopsis pilosula, 8-15 parts of cordate houttuynia, 8-15 parts of polygonum multiflorum, 5-10 parts of calendula officinalis, 5-10 parts of sedum, 5-8 parts of pawpaws, 5-8 parts of cassia twigs, 2-4 parts of indian strawberry extrac, 2-4 parts of selaginella tamariscina extract and 2-4 parts of spirulina extract. Compared with the prior art, the health-care food is free of toxic and side effects, and has the nutritive value and the anxiety improving function, and an experiment verifies and shows that the anxiety-improving health-care food has the remarkable effect of improving anxiety.
Description
Technical field
The present invention relates to field of food health care, a kind of health food improving anxiety and preparation method thereof.
Background technology
Anxiety neurosis is equally the psychosis of class serious harm people's quality of life with depression, and affects face relatively
Depression is more extensive.The generation of anxiety neurosis is accelerated to social rhythm, competition is fiercer the most relevant, therefore sends out along with society
Exhibition, the sickness rate of anxiety neurosis is improving.According to statistics, in China's urban population, the sickness rate of anxiety neurosis is about 1-2%, and flourishing state
Family nearly 10%, and still show a rising trend.According to a current research of Decision Resources, the main doctor in 7, the current world
More than 8,700 ten thousand anxiety neurosis patients are had on medicine market (U.S., France, Germany, Italy, Spain, Britain and Japan).Make medication
Thing improves anxiety function, not only inconvenient, and usually can bring pain with a series of side reaction to patient's daily life
Hardship, is therefore badly in need of the health food researched and developed a kind of human body effect good absorbing, have no side effect.
Summary of the invention
It is an object of the invention to provide a kind of health food improving anxiety and preparation method thereof.
For achieving the above object, the present invention provides following technical scheme:
A kind of health food improving anxiety, according to the component of weight portion be: Radix Achyranthis Bidentatae 20-30 part, Os Draconis 12-20 part, Radix Codonopsis 10-
15 parts, Herba Houttuyniae 8-15 part, Radix Polygoni Multiflori 8-15 part, Calendula officinalis 5-10 part, Herba hylotelephii erythrosticti 5-10 part, Fructus Chaenomelis 5-8 part, Ramulus Cinnamomi 5-8 part, Serpentis
Certain kind of berries extract 2-4 part, Herba Selaginellae extract 2-4 part, spirulina extract 2-4 part.
As the further scheme of the present invention: the described health food improving anxiety, according to the component of weight portion it is: Radix Achyranthis Bidentatae
25 parts, Os Draconis 16 parts, Radix Codonopsis 13 parts, Herba Houttuyniae 12 parts, Radix Polygoni Multiflori 13 parts, Calendula officinalis 8 parts, Herba hylotelephii erythrosticti 8 parts, Fructus Chaenomelis 7 parts, Ramulus Cinnamomi 7
Part, Herba Duchesneae Indicae extract 3 parts, Herba Selaginellae extract 3 parts, spirulina extract 3 parts.
As the further scheme of the present invention: described Herba Duchesneae Indicae extract is by supercritical titanium dioxide by the Herba Duchesneae Indicae after pulverizing
Carbon extraction is the most freeze-dried to be obtained, supercritical carbon dioxide extraction pressure 17MPa, extraction temperature 44 DEG C, separating pressure
3MPa, separation temperature 40 DEG C.
As the further scheme of the present invention: described Herba Selaginellae extract is by supercritical titanium dioxide by the Herba Selaginellae after pulverizing
Carbon extraction is the most freeze-dried to be obtained, supercritical carbon dioxide extraction pressure 8MPa, extraction temperature 38 DEG C, separating pressure
4MPa, separation temperature 38 DEG C.
As the further scheme of the present invention: described spirulina extract is by supercritical two by the spirulina after pulverizing
Carbonoxide extraction is the most freeze-dried to be obtained, supercritical carbon dioxide extraction pressure 17MPa, and extraction temperature 42 DEG C separates pressure
Power 8MPa, separation temperature 37 DEG C.
The preparation method of the described health food improving anxiety, is made as follows:
(1) be first according to described weight portion and weigh Radix Achyranthis Bidentatae, Os Draconis, Radix Codonopsis, Herba Houttuyniae, steaming and decocting after adding water, boiling temperature 40 DEG C-
50 DEG C, steaming and decocting carries out vacuum evaporation at 20 DEG C-30 DEG C after terminating, and obtains mixture I;
(2) then, Radix Polygoni Multiflori, Calendula officinalis, Herba hylotelephii erythrosticti, Fructus Chaenomelis, Ramulus Cinnamomi are carried out micronizing, is sufficiently stirred for mixture I subsequently
Mixing, obtains mixtures II;
(3) last, mixtures II is carried out high-speed homogenization, after drying with Herba Duchesneae Indicae extract, Herba Selaginellae extract and spiral extract
It is fabricated to tabletting or fills capsule, and carrying out packaging sterilizing.
As the further scheme of the present invention: step (1) boiling temperature is at 45 DEG C, and steaming and decocting carries out vacuum at 25 DEG C after terminating
Evaporation and concentration.
Compared with prior art, the invention has the beneficial effects as follows:
The health food of gained of the present invention, has no side effect, the most nutritious, can improve again anxiety function, experiment proves that
Find that there is the remarkable result improving anxiety.
Detailed description of the invention
Below in conjunction with detailed description of the invention, the technical scheme of this patent is described in more detail.
Embodiment 1
A kind of health food improving anxiety, according to the component of weight portion be: Radix Achyranthis Bidentatae 20 parts, Os Draconis 12 parts, Radix Codonopsis 10 parts, fish raw meat
Grass 8 parts, Radix Polygoni Multiflori 8 parts, Calendula officinalis 5 parts, Herba hylotelephii erythrosticti 5 parts, Fructus Chaenomelis 5 parts, Ramulus Cinnamomi 5 parts, Herba Duchesneae Indicae extract 2 parts, Herba Selaginellae extract 2
Part, spirulina extract 2 parts;Described Herba Duchesneae Indicae extract is to be passed through supercritical carbon dioxide extraction again through cold by the Herba Duchesneae Indicae after pulverizing
Freeze and be dried to obtain, supercritical carbon dioxide extraction pressure 17MPa, extraction temperature 44 DEG C, separating pressure 3MPa, separation temperature 40
℃;Described Herba Selaginellae extract is to be obtained by supercritical carbon dioxide extraction is the most freeze-dried by the Herba Selaginellae after pulverizing, super
Critical carbon dioxide extracting pressure 8MPa, extraction temperature 38 DEG C, separating pressure 4MPa, separation temperature 38 DEG C;Described spirulina carries
Taking thing is to be obtained by supercritical carbon dioxide extraction is the most freeze-dried by the spirulina after pulverizing, supercritical carbon dioxide
Extracting pressure 17MPa, extraction temperature 42 DEG C, separating pressure 8MPa, separation temperature 37 DEG C.
The preparation method of the described health food improving anxiety, is made as follows:
(1) be first according to described weight portion and weigh Radix Achyranthis Bidentatae, Os Draconis, Radix Codonopsis, Herba Houttuyniae, steaming and decocting after adding water, boiling temperature at 40 DEG C,
Steaming and decocting carries out vacuum evaporation at 20 DEG C after terminating, and obtains mixture I;
(2) then, Radix Polygoni Multiflori, Calendula officinalis, Herba hylotelephii erythrosticti, Fructus Chaenomelis, Ramulus Cinnamomi are carried out micronizing, is sufficiently stirred for mixture I subsequently
Mixing, obtains mixtures II;
(3) last, mixtures II is carried out high-speed homogenization, after drying with Herba Duchesneae Indicae extract, Herba Selaginellae extract and spiral extract
It is fabricated to tabletting or fills capsule, and carrying out packaging sterilizing.
Embodiment 2
A kind of health food improving anxiety, according to the component of weight portion be: Radix Achyranthis Bidentatae 25 parts, Os Draconis 16 parts, Radix Codonopsis 13 parts, fish raw meat
Grass 12 parts, Radix Polygoni Multiflori 13 parts, Calendula officinalis 8 parts, Herba hylotelephii erythrosticti 8 parts, Fructus Chaenomelis 7 parts, Ramulus Cinnamomi 7 parts, Herba Duchesneae Indicae extract 3 parts, Herba Selaginellae extract 3
Part, spirulina extract 3 parts;Described Herba Duchesneae Indicae extract is to be passed through supercritical carbon dioxide extraction again through cold by the Herba Duchesneae Indicae after pulverizing
Freeze and be dried to obtain, supercritical carbon dioxide extraction pressure 17MPa, extraction temperature 44 DEG C, separating pressure 3MPa, separation temperature 40
℃;Described Herba Selaginellae extract is to be obtained by supercritical carbon dioxide extraction is the most freeze-dried by the Herba Selaginellae after pulverizing, super
Critical carbon dioxide extracting pressure 8MPa, extraction temperature 38 DEG C, separating pressure 4MPa, separation temperature 38 DEG C;Described spirulina carries
Taking thing is to be obtained by supercritical carbon dioxide extraction is the most freeze-dried by the spirulina after pulverizing, supercritical carbon dioxide
Extracting pressure 17MPa, extraction temperature 42 DEG C, separating pressure 8MPa, separation temperature 37 DEG C.
The preparation method of the described health food improving anxiety, is made as follows:
(1) be first according to described weight portion and weigh Radix Achyranthis Bidentatae, Os Draconis, Radix Codonopsis, Herba Houttuyniae, steaming and decocting after adding water, boiling temperature at 45 DEG C,
Steaming and decocting carries out vacuum evaporation at 25 DEG C after terminating, and obtains mixture I;
(2) then, Radix Polygoni Multiflori, Calendula officinalis, Herba hylotelephii erythrosticti, Fructus Chaenomelis, Ramulus Cinnamomi are carried out micronizing, is sufficiently stirred for mixture I subsequently
Mixing, obtains mixtures II;
(3) last, mixtures II is carried out high-speed homogenization, after drying with Herba Duchesneae Indicae extract, Herba Selaginellae extract and spiral extract
It is fabricated to tabletting or fills capsule, and carrying out packaging sterilizing.
Embodiment 3
A kind of health food improving anxiety, according to the component of weight portion be: Radix Achyranthis Bidentatae 30 parts, Os Draconis 20 parts, Radix Codonopsis 15 parts, fish raw meat
Grass 15 parts, Radix Polygoni Multiflori 15 parts, Calendula officinalis 10 parts, Herba hylotelephii erythrosticti 10 parts, Fructus Chaenomelis 8 parts, Ramulus Cinnamomi 8 parts, Herba Duchesneae Indicae extract 4 parts, Herba Selaginellae are extracted
Thing 4 parts, spirulina extract 4 parts;Described Herba Duchesneae Indicae extract is by the Herba Duchesneae Indicae after pulverizing by supercritical carbon dioxide extraction again
Freeze-dried obtain, supercritical carbon dioxide extraction pressure 17MPa, extraction temperature 44 DEG C, separating pressure 3MPa, separate temperature
Spend 40 DEG C;Described Herba Selaginellae extract is to be obtained by supercritical carbon dioxide extraction is the most freeze-dried by the Herba Selaginellae after pulverizing
, supercritical carbon dioxide extraction pressure 8MPa, extraction temperature 38 DEG C, separating pressure 4MPa, separation temperature 38 DEG C;Described spiral
Algae extract is to be obtained by supercritical carbon dioxide extraction is the most freeze-dried by the spirulina after pulverizing, supercritical dioxy
Change carbon extracting pressure 17MPa, extraction temperature 42 DEG C, separating pressure 8MPa, separation temperature 37 DEG C.
The preparation method of the described health food improving anxiety, is made as follows:
(1) be first according to described weight portion and weigh Radix Achyranthis Bidentatae, Os Draconis, Radix Codonopsis, Herba Houttuyniae, steaming and decocting after adding water, boiling temperature at 50 DEG C,
Steaming and decocting carries out vacuum evaporation at 30 DEG C after terminating, and obtains mixture I;
(2) then, Radix Polygoni Multiflori, Calendula officinalis, Herba hylotelephii erythrosticti, Fructus Chaenomelis, Ramulus Cinnamomi are carried out micronizing, is sufficiently stirred for mixture I subsequently
Mixing, obtains mixtures II;
(3) last, mixtures II is carried out high-speed homogenization, after drying with Herba Duchesneae Indicae extract, Herba Selaginellae extract and spiral extract
It is fabricated to tabletting or fills capsule, and carrying out packaging sterilizing.
The test of pesticide effectiveness:
Given the test agent: the health food of the present embodiment 2 preparation.
Positive control: chlormezanone sheet (Dandong Yi Chuan Pharmaceutical Co., Ltd).
Employing elevated plus maze test is tested, according to Lister(Lister R.The use of a plus-maze to
measure anxiety in the mouse.Psychopharmacology, 92,180-185 (1987)) method, experiment
Animal is provided by Medical University Of Anhui's Experimental Animal Center for NIH kind mice 18-22g(), it is randomly divided into (the high agent of given the test agent group
Amount 1000mg/kg, middle dosage 500mg/kg, low dosage 250mg/kg), blank group, positive control (20mg/kg), often group
50.Experiment is at room temperature carried out, and keeps nature circadian rhythm simultaneously.First mice adaptability in elevated plus maze test is allowed to instruct
Practicing 3 days, each 5 minutes, then carry out drug study, every mice is once carried out 5 minutes, and observational record mice enters open logical
Residence time after road, closed access.Experimental result is shown in Table 1.
The impact on mouse anxiety behavior in Elevated plus-maze of table 1 given the test agent
* P < 0.01, compared with blank group
Can be obtained by upper table 1, given the test agent can dramatically increase mice and enter residence time after open access, reduces at closed access
The time of staying, similar with antianxiety drug chlormezanone sheet effect, illustrate that this health food has activity antianxity.
It is obvious to a person skilled in the art that the invention is not restricted to the details of above-mentioned one exemplary embodiment, Er Qie
In the case of the spirit or essential attributes of the present invention, it is possible to realize the present invention in other specific forms.Therefore, no matter
From the point of view of which point, all should regard embodiment as exemplary, and be nonrestrictive, the scope of the present invention is by appended power
Profit requires rather than described above limits, it is intended that all by fall in the implication of equivalency and scope of claim
Change is included in the present invention.
Although moreover, it will be appreciated that this specification is been described by according to embodiment, but the most each embodiment only wraps
Containing an independent technical scheme, this narrating mode of description is only that for clarity sake those skilled in the art should
Description can also be formed those skilled in the art through appropriately combined as an entirety, the technical scheme in each embodiment
May be appreciated other embodiments.
Claims (7)
1. the health food improving anxiety, it is characterised in that be according to the component of weight portion: Radix Achyranthis Bidentatae 20-30 part, Os Draconis
12-20 part, Radix Codonopsis 10-15 part, Herba Houttuyniae 8-15 part, Radix Polygoni Multiflori 8-15 part, Calendula officinalis 5-10 part, Herba hylotelephii erythrosticti 5-10 part, Fructus Chaenomelis 5-8
Part, Ramulus Cinnamomi 5-8 part, Herba Duchesneae Indicae extract 2-4 part, Herba Selaginellae extract 2-4 part, spirulina extract 2-4 part.
The health food improving anxiety the most according to claim 1, it is characterised in that the described health care food improving anxiety
Product, according to the component of weight portion be: Radix Achyranthis Bidentatae 25 parts, Os Draconis 16 parts, Radix Codonopsis 13 parts, Herba Houttuyniae 12 parts, Radix Polygoni Multiflori 13 parts, Calendula officinalis
8 parts, Herba hylotelephii erythrosticti 8 parts, Fructus Chaenomelis 7 parts, Ramulus Cinnamomi 7 parts, Herba Duchesneae Indicae extract 3 parts, Herba Selaginellae extract 3 parts, spirulina extract 3 parts.
The health food improving anxiety the most according to claim 1 and 2, it is characterised in that described Herba Duchesneae Indicae extract be by
Herba Duchesneae Indicae after pulverizing obtains by supercritical carbon dioxide extraction is the most freeze-dried, supercritical carbon dioxide extraction pressure
17MPa, extraction temperature 44 DEG C, separating pressure 3MPa, separation temperature 40 DEG C.
The health food improving anxiety the most according to claim 3, it is characterised in that described Herba Selaginellae extract is by pulverizing
After Herba Selaginellae obtain by supercritical carbon dioxide extraction is the most freeze-dried, supercritical carbon dioxide extraction pressure 8MPa,
Extraction temperature 38 DEG C, separating pressure 4MPa, separation temperature 38 DEG C.
The health food improving anxiety the most according to claim 4, it is characterised in that described spirulina extract is by powder
Spirulina after broken obtains by supercritical carbon dioxide extraction is the most freeze-dried, supercritical carbon dioxide extraction pressure
17MPa, extraction temperature 42 DEG C, separating pressure 8MPa, separation temperature 37 DEG C.
6. according to the preparation method of the arbitrary described health food improving anxiety of claim 1-5, it is characterised in that by such as
Lower step is made:
(1) being first according to described weight portion and weigh Radix Achyranthis Bidentatae, Os Draconis, Radix Codonopsis, Herba Houttuyniae, steaming and decocting after adding water, boiling temperature is 40
DEG C-50 DEG C, steaming and decocting carries out vacuum evaporation at 20 DEG C-30 DEG C after terminating, and obtains mixture I;
(2) then, Radix Polygoni Multiflori, Calendula officinalis, Herba hylotelephii erythrosticti, Fructus Chaenomelis, Ramulus Cinnamomi are carried out micronizing, is sufficiently stirred for mixture I subsequently
Mixing, obtains mixtures II;
(3) last, mixtures II is carried out high-speed homogenization, after drying with Herba Duchesneae Indicae extract, Herba Selaginellae extract and spiral extract
It is fabricated to tabletting or fills capsule, and carrying out packaging sterilizing.
The preparation method of the health food improving anxiety the most according to claim 6, it is characterised in that step (1) steaming and decocting
Temperature is at 45 DEG C, and steaming and decocting carries out vacuum evaporation at 25 DEG C after terminating.
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