CN102614235A - Acanthopanax root tea paste and preparation method thereof - Google Patents
Acanthopanax root tea paste and preparation method thereof Download PDFInfo
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- CN102614235A CN102614235A CN2012101319000A CN201210131900A CN102614235A CN 102614235 A CN102614235 A CN 102614235A CN 2012101319000 A CN2012101319000 A CN 2012101319000A CN 201210131900 A CN201210131900 A CN 201210131900A CN 102614235 A CN102614235 A CN 102614235A
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Abstract
The invention relates to acanthopanax root tea paste and a preparation method thereof. The acanthopanax root tea paste is mainly prepared from an acanthopanax extract and a disintegrating agent. The preparation method comprises the following steps of: firstly, drying the acanthopanax extract, mixing the disintegrating agent with the dried acanthopanax extract into a pile which is completely wet, in a consistent color, of appropriate hardness, non-sticky and non-cracking; preparing a piled soft material into wet pills; and packing the wet pills into a product. The acanthopanax root tea paste has the effects of tonifying qi and spleen, tonifying kidney and calming the nerves, and has good curative effects on insufficiency of both the spleen and the kindey, adynamia, inappetency, soreness of the waist and knees, insomnia and dreamful sleep. In the acanthopanax root tea paste, a pure natural pollution-free plant, i.e., acanthopanax is taken as a raw material, so that the acanthopanax root tea paste has the function of regulating organism metabolism, and can be used for enhancing the resistance of organisms to various diseases.
Description
Technical field
The present invention relates to the health food technology field, specifically, relate to a kind of Radix Et Caulis Acanthopanacis Senticosi tea ointment and preparation method thereof.
Background technology
Radix Et Caulis Acanthopanacis Senticosi belongs to Araliaceae, with Radix Ginseng be same section, main product ground is the mountain area northeastward, is the distinctive a kind of rare Chinese medicine in the Northeast.Its active ingredient mainly is syringoside, flavonoid active substance, has replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization, to the prevention heart, cerebrovascular disease, and deficiency of spleen-YANG and kidneyYANG, body void is weak, inappetence, soreness of waist and knee joint, insomnia and dreamful sleep has certain curative effect.
The effect characteristics and the Radix Ginseng of modern medicine research proof Radix Et Caulis Acanthopanacis Senticosi are basic identical, have the disorder of the body of adjusting and make it to be tending towards normal function.Good antifatigue effect is arranged, remarkable than Radix Ginseng, and can significantly improve hypoxia-bearing capability.Have functions such as invigorating middle warmer, smart, the strong will of benefit, wind-damp dispelling, strengthening bone and muscle, blood circulation and promoting silt, the diuresis of being good for the stomach.Radix Et Caulis Acanthopanacis Senticosi contains acanthoside, and it can stimulate the mind & body vigor.Numerous scientific publication things about Radix Et Caulis Acanthopanacis Senticosi have proved its antifatigue effect, strengthen endurance and ability, increase alertness and learning capacity.Numerous usages have all obtained confirmation in human experimentation.At present there is the report of considerable quantity to point out that it has the support immune system equally, recovers improper hypotension, improve blood circulation, make disorderly glycolipid metabolism normalization, liver, testis, the anabolic effect of bone density and other vitals.
CN 1989988A relates to a kind of acanthopanax root dispersed tablet.This invention medicine is raw material with the Radix Et Caulis Acanthopanacis Senticosi, and the fine powder of preparation Radix Et Caulis Acanthopanacis Senticosi extract adds the acanthopanax root dispersed tablet that appropriate amount of auxiliary materials is processed in 3 minutes disintegrate fully and reached homogeneously dispersed state, replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization.
CN 1530121A discloses a kind of Radix Et Caulis Acanthopanacis Senticosi soft capsule, has solved Chinese medicine onset shortcoming slowly.Get Radix Et Caulis Acanthopanacis Senticosi extractum, add tween 80, Semen sojae atricolor wet goods vegetable oil, mixing is pressed into soft capsule.Be used to treat deficiency of spleen-YANG and kidneyYANG, body void is weak, inappetence, soreness of waist and knee joint, insomnia and dreamful sleep.
The existing acanthopanax senticosus health promoting beverage aspect dosage form, is main with capsule, tablet mainly; Type of dosage form is few, and the amount of taking is greatly and very inconvenient, and health-care effect is not remarkable; On effect, there is serious deficiency, and method for preparing and processing step more complicated.Tea is approved by whole world each age group crowd as a kind of good merchantable brand of health care that as three big non-alcoholic drinks especially bottled ball is taking convenience safety not only, and can avoid the poisoning that causes owing to the infusion of tea overlong time.
Summary of the invention
For overcome existing acanthopanax senticosus drinks health care effect not significantly, deficiencies such as method for preparing and complex process, the present invention provides a kind of Radix Et Caulis Acanthopanacis Senticosi tea ointment and preparation method thereof.The object of the invention at first is to provide a kind of Radix Et Caulis Acanthopanacis Senticosi tea ointment with health role.Another object of the present invention provides a kind of method for preparing of Radix Et Caulis Acanthopanacis Senticosi tea ointment.
For reaching this purpose, the present invention adopts following technical scheme:
A kind of Radix Et Caulis Acanthopanacis Senticosi tea ointment, said Radix Et Caulis Acanthopanacis Senticosi tea ointment is mainly processed by Radix Et Caulis Acanthopanacis Senticosi extractum and disintegrating agent.Other adjuvants can be added according to common practise and practical experience by those skilled in the art.
The parts by weight of Radix Et Caulis Acanthopanacis Senticosi extractum according to the invention are 60～95, for example 61～94,65～90,73～87,78～83,81 etc., and preferred 75～85, further preferred 80.
Further, said disintegrating agent parts by weight are 5～40, for example 6～38,10～32,13～29,17～25,19～22,20 etc., and preferred 15～25, further preferred 20.
For example; Radix Et Caulis Acanthopanacis Senticosi tea ointment according to the invention is processed by the Radix Et Caulis Acanthopanacis Senticosi extractum of 60 weight portions and the disintegrating agent of 40 weight portions; Or process by the Radix Et Caulis Acanthopanacis Senticosi extractum of 95 weight portions and the disintegrating agent of 5 weight portions; Or process by the Radix Et Caulis Acanthopanacis Senticosi extractum of 75 weight portions and the disintegrating agent of 25 weight portions, or process by the Radix Et Caulis Acanthopanacis Senticosi extractum of 85 weight portions and the disintegrating agent of 15 weight portions, most preferably process by the Radix Et Caulis Acanthopanacis Senticosi extractum of 80 weight portions and the disintegrating agent of 20 weight portions.
Further, the content >=120mg of total flavonoid in per 0.3 gram Radix Et Caulis Acanthopanacis Senticosi tea ointment.Flavone compound in the Radix Et Caulis Acanthopanacis Senticosi has pharmacologically active widely.Biological general flavone is meant flavone compound, is one big type of natural product, extensively is present in plant kingdom, is many medium-height grass the effective elements of the medicines.Modal at occurring in nature is flavone and flavonol, and other comprises two hydrogen yellow (alcohol), isoflavone, bisflavone, flavonol, chalcone, aurones, anthocyanin and neoflavonoid etc.
Disintegrating agent is meant and can makes medicament in gastro-intestinal Fluid, split the material that is broken into fine particle rapidly, thereby makes functional component dissolve absorption rapidly, plays a role.This type material mostly has good water absorption and dilatancy, thereby realizes the disintegrate of medicament.Disintegrating agent according to the invention is selected from the mixture of a kind of in carboxymethyl starch sodium, low-substituted hydroxypropyl cellulose, cross-linking sodium carboxymethyl cellulose or the crospolyvinylpyrrolidone or at least two kinds; Carboxymethyl starch sodium for example; Low-substituted hydroxypropyl cellulose/cross-linking sodium carboxymethyl cellulose; Carboxymethyl starch sodium/low-substituted hydroxypropyl cellulose/crospolyvinylpyrrolidone etc., further preferred carboxymethyl starch sodium and/or crospolyvinylpyrrolidone, most preferably crospolyvinylpyrrolidone.Crospolyvinylpyrrolidone is white or near-white, has the runny powder of hygroscopicity, odorless or little smelly, water insoluble, alkali, acid and organic solvent commonly used, have very strong expansion character and with the complexing power of multiclass material.In medical industry,, also can be used as the disintegrating agent and the filler of pill, granule, hard capsule mainly as the disintegrating agent of tablet.
Of the present invention " mainly by ... process ", mean it except that said component, can also comprise other components, these other components are given said Radix Et Caulis Acanthopanacis Senticosi tea ointment different characteristic.In addition, of the present invention " mainly by ... process ", can also replace with enclosed " being " or " by ... process ".
The present invention also provides a kind of method for preparing of Radix Et Caulis Acanthopanacis Senticosi tea ointment, may further comprise the steps:
(1) Radix Et Caulis Acanthopanacis Senticosi extractum being dried to water content is 10～35%;
(2) disintegrating agent and dried Radix Et Caulis Acanthopanacis Senticosi extractum are mixed to become to stick together and all moisten, color and luster is consistent, and soft or hard is suitable, and is tack-free, not dry and cracked;
(3) become the soft material after sticking together to process wet pill step (2);
(4) pill that will wet is dried to water content≤8% back packing and processes product.
Further, the baking temperature of said step (1) is 35～80 ℃, for example 36～78 ℃, and 40～72 ℃, 44～65 ℃, 48～62 ℃, 53～58 ℃, 56 ℃ etc., preferred 45～60 ℃, further preferred 55 ℃.
Further, the incorporation time of said step (2) is 6～22min, 8～20min for example, 11～17min, 13～15min, 14min etc., preferred 10～15min, further preferred 12min.
Further, the wet pill particle diameter that said step (3) is processed is 2～13mm, 2～11mm for example, 3～9mm, 5～8mm, 6mm etc., preferred 3～8mm, further preferred 5mm.
Further, the baking temperature of said step (4) is 30～80 ℃, for example 32～75 ℃, and 38～68 ℃, 45～60 ℃, 48～55 ℃, 50 ℃ etc., preferred 45～60 ℃, further preferred 52 ℃.
Further, be 2～5.5h drying time, 2.05～5.4h for example, 2.3～5h, 2.5～4.7h, 2.9～4.4h, 3.5～4h, 3.8h etc., preferred 3～4h, further preferred 3.6h.
Again further, put into desiccant during packing.Desiccant also is absorbent, is to be used in protection against the tide, and the mildew-resistant aspect plays desiccation, is not all branch physical absorption desiccant and chemisorbed desiccant by suction type and product.The desiccant of physical absorption has silica gel, alumina gel, molecular sieve, active carbon, bone black, Linesless charcoal, mineral agent, or active hargil etc., its drying principles is exactly through physics mode hydrone to be adsorbed in the structure of self.
The present invention with the mode of disintegrating agent for adding, Nei Jia or in add, add bonded mode.
A kind of method for preparing of Radix Et Caulis Acanthopanacis Senticosi tea ointment may further comprise the steps after the optimization of process conditions:
(1) take by weighing the Radix Et Caulis Acanthopanacis Senticosi extractum of 75～85 weight portions, putting into the hot air circulation drying baker, to be dried to water content be 15～25%, and baking temperature is set to 45～60 ℃;
(2) disintegrating agent and the dried Radix Et Caulis Acanthopanacis Senticosi extractum that take by weighing 15～25 weight portions mix 10～15min in mixer, one-tenth sticks together and all moistens, and color and luster is consistent, and soft or hard is suitable, and is tack-free, not dry and cracked;
(3) become the soft material after sticking together to process the wet pill that particle diameter is 3～8mm step (2);
(4) pill that will wet moves in the hot air circulation drying baker, and dry 3～4h is dried to water content≤5% under 45～60 ℃ of temperature;
(5) with dried pill bottling, and in bottle, put into desiccant, packing is processed product.
Compare with the prior art scheme, the present invention has following beneficial effect:
The present invention has the effect of replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization, and to deficiency of spleen-YANG and kidneyYANG, body void is weak, inappetence, and soreness of waist and knee joint, insomnia and dreamful sleep has certain curative effect.And have and meet water disintegrate fast, more be prone to patient's acceptance and take, portably use characteristics such as more convenient.The preferred adjuvant of the present invention can make that the disintegrate of Radix Et Caulis Acanthopanacis Senticosi tea ointment is more quick.
Raw material of the present invention adopts fully natural green pollution plants-Radix Et Caulis Acanthopanacis Senticosi, has the metabolic function of the body of adjusting, and enhancing body is the health product of good tranquillizing and allaying excitement to the resistivity of various diseases.
Inner packing of the present invention adopts bottled form, has no side effect, and box-packed form is adopted in outer package, and is easy to carry.
Down in the face of further explain of the present invention.But following instance only is a simple and easy example of the present invention, does not represent or limits rights protection scope of the present invention, and interest field of the present invention is as the criterion with claims.
The specific embodiment
For the present invention is described better, be convenient to understand technical scheme of the present invention, typical case of the present invention but non-restrictive example is following:
Embodiment 1
The Radix Et Caulis Acanthopanacis Senticosi extractum of 85 weight portions is dried to water content under 50 ℃ in the hot air circulation drying baker be 20%, and the crospolyvinylpyrrolidone that takes by weighing 15 weight portions puts into mixer mixing 8min as disintegrating agent with dried Radix Et Caulis Acanthopanacis Senticosi extractum simultaneously, becomes to stick together and all moisten; Color and luster is consistent, and soft or hard is suitable, and is tack-free; Not dry and cracked, selecting mould is the pellet processing machine of φ=5mm, and the soft material after one-tenth is sticked together is processed the wet pill that particle diameter is 5mm; Move in the hot air circulation drying baker, 50 ℃ of dry 3.6h are 5% to water content, every 0.1g; Adopt ultraviolet spectrophotometry 510nm wavelength to detect down, every contains total flavones 40mg, then bottling; 120 every bottle, two bottled boxes are finished product.Get 5～6 of Radix Et Caulis Acanthopanacis Senticosi tea ointment when taking, bubble is gone into molten opening, i.e. orally-ingestible in the boiled water at every turn.Take every day 1～2 time.
Embodiment 2
The Radix Et Caulis Acanthopanacis Senticosi extractum of 60 weight portions is dried to water content under 35 ℃ in the hot air circulation drying baker be 35%, and the crospolyvinylpyrrolidone that takes by weighing 40 weight portions puts into mixer mixing 12min as disintegrating agent with dried Radix Et Caulis Acanthopanacis Senticosi extractum simultaneously, becomes to stick together and all moisten; Color and luster is consistent, and soft or hard is suitable, and is tack-free; Not dry and cracked, selecting mould is the pellet processing machine of φ=8mm, and the soft material after one-tenth is sticked together is processed the wet pill that particle diameter is 8mm; Move in the hot air circulation drying baker, 80 ℃ of dry 2h are to moisture content 6%, every 0.3g; Adopt ultraviolet spectrophotometry 510nm wavelength to detect down, every contains total flavones 125mg, then bottling; 90 every bottle, two bottled boxes are finished product.Get 1～2 of Radix Et Caulis Acanthopanacis Senticosi tea ointment when taking, bubble is gone into boiled water and is dissolved and open, i.e. orally-ingestible at every turn.Take every day 1～2 time.
Embodiment 3
The Radix Et Caulis Acanthopanacis Senticosi extractum of 75 weight portions is dried to water content under 80 ℃ in the hot air circulation drying baker be 10%, and the crospolyvinylpyrrolidone that takes by weighing 25 weight portions puts into mixer mixing 6min as disintegrating agent with dried Radix Et Caulis Acanthopanacis Senticosi extractum simultaneously, becomes to stick together and all moisten; Color and luster is consistent, and soft or hard is suitable, and is tack-free; Not dry and cracked, selecting mould is the pellet processing machine of φ=11mm, and the soft material after one-tenth is sticked together is processed the wet pill that particle diameter is 11mm; Move in the hot air circulation drying baker, 30 ℃ of dry 5.5h are 8% to water content, every 0.7g; Adopt ultraviolet spectrophotometry 510nm wavelength to detect down, every contains total flavones 280mg, then bottling; 30 every bottle, two bottled boxes are finished product.Get 1～2 of Radix Et Caulis Acanthopanacis Senticosi tea ointment when taking, bubble is gone into molten opening, i.e. orally-ingestible in the boiled water at every turn.Take every day 1 time.
Embodiment 4
The Radix Et Caulis Acanthopanacis Senticosi extractum of 95 weight portions is dried to water content under 45 ℃ in the hot air circulation drying baker be 16%, and the low-substituted hydroxypropyl cellulose that takes by weighing 5 weight portions puts into mixer mixing 22min as disintegrating agent with dried Radix Et Caulis Acanthopanacis Senticosi extractum simultaneously, becomes to stick together and all moisten; Color and luster is consistent, and soft or hard is suitable, and is tack-free; Not dry and cracked, selecting mould is the pellet processing machine of φ=2mm, and the soft material after one-tenth is sticked together is processed the wet pill that particle diameter is 2mm; Move in the hot air circulation drying baker, 60 ℃ of dry 3h are 4% to water content, every 0.06g; Adopt ultraviolet spectrophotometry 510nm wavelength to detect down, every contains total flavones 25mg, then bottling; 200 every bottle, two bottled boxes are finished product.Get 7～8 of Radix Et Caulis Acanthopanacis Senticosi tea ointment when taking, bubble is gone into molten opening, i.e. orally-ingestible in the boiled water at every turn.Take every day 1～2 time.
Embodiment 5
The Radix Et Caulis Acanthopanacis Senticosi extractum of 80 weight portions is dried to water content under 60 ℃ in the hot air circulation drying baker be 22%, and the cross-linking sodium carboxymethyl cellulose that takes by weighing 20 weight portions puts into mixer mixing 10min as disintegrating agent with dried Radix Et Caulis Acanthopanacis Senticosi extractum simultaneously, becomes to stick together and all moisten; Color and luster is consistent, and soft or hard is suitable, and is tack-free; Not dry and cracked, selecting mould is the pellet processing machine of φ=13mm, and the soft material after one-tenth is sticked together is processed the wet pill that particle diameter is 13mm; Move in the hot air circulation drying baker, 45 ℃ of dry 4h are 5% to water content, every 1g; Adopt ultraviolet spectrophotometry 510nm wavelength to detect down, every contains total flavones 400mg, then bottling; 20 every bottle, two bottled boxes are finished product.Get 1 of Radix Et Caulis Acanthopanacis Senticosi tea ointment when taking, bubble is gone into molten opening, i.e. orally-ingestible in the boiled water at every turn.Take every day 1 time.
Embodiment 6
The Radix Et Caulis Acanthopanacis Senticosi extractum of 78 weight portions is dried to water content under 55 ℃ in the hot air circulation drying baker be 28%, and the crospolyvinylpyrrolidone that takes by weighing 22 weight portions puts into mixer mixing 15min as disintegrating agent with dried Radix Et Caulis Acanthopanacis Senticosi extractum simultaneously, becomes to stick together and all moisten; Color and luster is consistent, and soft or hard is suitable, and is tack-free; Not dry and cracked, selecting mould is the pellet processing machine of φ=5mm, and the soft material after one-tenth is sticked together is processed the wet pill that particle diameter is 5mm; Move in the hot air circulation drying baker, 52 ℃ of dry 3.5h are 5% to water content, every 0.25g; Adopt ultraviolet spectrophotometry 510nm wavelength to detect down, every contains total flavones 135mg, then bottling; 100 every bottle, two bottled boxes are finished product.Get 4～5 of Radix Et Caulis Acanthopanacis Senticosi tea ointment when taking, bubble is gone into molten opening, i.e. orally-ingestible in the boiled water at every turn.Take every day 1 time.
Applicant's statement; The person of ordinary skill in the field is on the basis of the foregoing description, and is with the concrete content point value of the foregoing description component, combined with the technical scheme of summary of the invention part; Thereby the new numerical range that produces; Also be one of record scope of the present invention, the application is no longer enumerated these numerical rangies for making description simple and clear.
Function of the present invention is mainly replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization, clinically is mainly used in the treatment deficiency of both the splenic and pulmonary QI, suffers from a deficiency of the kidney, diseases such as soreness of waist and knee joint, deficiency of both the heart and spleen, insomnia forgetfulness.
1, for the therapeutical effect of test the present invention, selects leukopenia to 4 * 10 that cause because of multiple reason to leukopenia
9Following patient's 300 examples of individual/L are carried out clinical observation, select suitable leukopenia patient's 230 examples of medical history, the state of an illness, age and former Therapeutic Method as matched group simultaneously.The Radix Et Caulis Acanthopanacis Senticosi tea ointment that test group adopts the embodiment of the invention 1 to process is treated, and matched group is treated by conventional method.
Therapeutic Method: 5～6 of the Radix Et Caulis Acanthopanacis Senticosi tea ointment that every day, oral embodiment 1 processed, divide and take continuous use 14d 2 times.
Therapeutic outcome: test group causes leukopenic cancer patient because of chemotherapy, radiotherapy, and leukocyte all returns to normal level (4～10 * 10
9Individual/as L), can to continue to accept chemotherapy and radiation, all the other Most patients leukocyte all have rising in various degree.Wherein, produce effects 182 examples, effective 103 examples, invalid 15 examples, total effective rate is 95%.Show that the Radix Et Caulis Acanthopanacis Senticosi tea ointment truly has chemotherapy, the leukopenic effect of caused by radiation of preventing.
And according to the matched group patient of conventional method treatment, behind treatment 14d, produce effects 120 examples, effective 54 examples, invalid 56 examples, total effective rate is 75.6%.
2, for the therapeutical effect of test the present invention, select patient's 450 examples to carry out clinical observation, select suitable angina pectoris patient 500 examples of medical history, the state of an illness, age and former Therapeutic Method simultaneously as matched group to angina pectoris.The Radix Et Caulis Acanthopanacis Senticosi tea ointment that test group adopts the embodiment of the invention 3 to process is treated, and matched group is treated by conventional method.
Therapeutic Method: 1～2 of the Radix Et Caulis Acanthopanacis Senticosi tea ointment that every day, oral embodiment 3 processed, divide and take continuous use 14d 1 time.
Therapeutic outcome: test group produce effects 312 examples, effective 104 examples, invalid 34 examples, total effective rate is 92.4%.And according to the matched group patient of conventional method treatment, behind treatment 14d, produce effects 280 examples, effective 85 examples, invalid 135 examples, total effective rate is 73%, is starkly lower than test group.
In addition, test group patient's angina pectoris attacks number of times, angina pectoris attacks frequency are starkly lower than matched group, and aspects such as nitroglycerin consumption, electrocardiogram improvement and hemorheology figureofmerit all are superior to matched group.It is thus clear that Radix Et Caulis Acanthopanacis Senticosi tea ointment of the present invention is the active drug of treatment angina pectoris.
Applicant's statement, the present invention explains preparation process of the present invention through the foregoing description, but the present invention is not limited to above-mentioned preparation process, does not mean that promptly the present invention must rely on above-mentioned preparation process and could implement.The person of ordinary skill in the field should understand, and to any improvement of the present invention, to the interpolation of the equivalence replacement of raw material that the present invention selects for use and auxiliary element, the selection of concrete mode etc., all drops within protection scope of the present invention and the open scope.
Claims (10)
1. a Radix Et Caulis Acanthopanacis Senticosi tea ointment is characterized in that, said Radix Et Caulis Acanthopanacis Senticosi tea ointment is mainly processed by Radix Et Caulis Acanthopanacis Senticosi extractum and disintegrating agent.
2. Radix Et Caulis Acanthopanacis Senticosi tea ointment as claimed in claim 1 is characterized in that, the parts by weight of said Radix Et Caulis Acanthopanacis Senticosi extractum are 60～95, preferred 75～85, further preferred 80;
Preferably, the parts by weight of said disintegrating agent are 5～40, preferred 15～25, further preferred 20;
Preferably, the content >=120mg of total flavonoid in per 0.3 gram Radix Et Caulis Acanthopanacis Senticosi tea ointment.
3. according to claim 1 or claim 2 Radix Et Caulis Acanthopanacis Senticosi tea ointment; It is characterized in that; Said disintegrating agent is selected from the mixture of a kind of in carboxymethyl starch sodium, low-substituted hydroxypropyl cellulose, cross-linking sodium carboxymethyl cellulose or the crospolyvinylpyrrolidone or at least two kinds; Further preferred carboxymethyl starch sodium and/or crospolyvinylpyrrolidone, most preferably crospolyvinylpyrrolidone.
4. the method for preparing of a Radix Et Caulis Acanthopanacis Senticosi tea ointment is characterized in that, may further comprise the steps:
(1) Radix Et Caulis Acanthopanacis Senticosi extractum being dried to water content is 10～35%;
(2) disintegrating agent and dried Radix Et Caulis Acanthopanacis Senticosi extractum are mixed to become to stick together and all moisten, color and luster is consistent, and soft or hard is suitable, and is tack-free, not dry and cracked;
(3) become the soft material after sticking together to process wet pill step (2);
(4) pill that will wet is dried to water content≤8% back packing and processes product.
5. method as claimed in claim 4 is characterized in that, the baking temperature of said step (1) is 35～80 ℃, preferred 45～60 ℃, and further preferred 55 ℃.
6. like claim 4 or 5 described methods, it is characterized in that the incorporation time of said step (2) is 6～22min, preferred 10～15min, further preferred 12min.
7. like the described method of one of claim 4-6, it is characterized in that the wet pill particle diameter that said step (3) is processed is 2～13mm, preferred 3～8mm, further preferred 5mm.
8. like the described method of one of claim 4-7, it is characterized in that the baking temperature of said step (4) is 30～80 ℃, preferred 45～60 ℃, further preferred 52 ℃;
Preferably, be 2～5.5h drying time, preferred 3～4h, further preferred 3.6h;
Preferably, put into desiccant during packing.
9. like the described method of one of claim 4-8, it is characterized in that, with the mode of disintegrating agent for add and/or in add.
10. like the described method of one of claim 4-9, it is characterized in that, may further comprise the steps:
(1) take by weighing the Radix Et Caulis Acanthopanacis Senticosi extractum of 75～85 weight portions, putting into the hot air circulation drying baker, to be dried to water content be 15～25%, and baking temperature is 45～60 ℃;
(2) disintegrating agent and the dried Radix Et Caulis Acanthopanacis Senticosi extractum that take by weighing 15～25 weight portions mix 10～15min in mixer, one-tenth sticks together and all moistens, and color and luster is consistent, and soft or hard is suitable, and is tack-free, not dry and cracked;
(3) become the soft material after sticking together to process the wet pill that particle diameter is 3～8mm step (2);
(4) pill that will wet moves in the hot air circulation drying baker, and dry 3～4h is dried to water content≤5% under 45～60 ℃ of temperature;
(5) with dried pill bottling, and in bottle, put into desiccant, packing is processed product.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103392855A (en) * | 2013-07-18 | 2013-11-20 | 淄博职业学院 | Spleen-tonifying and blood-controlling health-care tea paste and preparation method thereof |
| CN106526156A (en) * | 2016-10-26 | 2017-03-22 | 王喜军 | Method for detecting, screening and identifying kidney-yang deficiency metabolism biomarkers |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1989988A (en) * | 2005-12-29 | 2007-07-04 | 江西本草天工科技有限责任公司 | Acanthopanax root dispersed tablet |
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2012
- 2012-04-28 CN CN2012101319000A patent/CN102614235A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1989988A (en) * | 2005-12-29 | 2007-07-04 | 江西本草天工科技有限责任公司 | Acanthopanax root dispersed tablet |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103392855A (en) * | 2013-07-18 | 2013-11-20 | 淄博职业学院 | Spleen-tonifying and blood-controlling health-care tea paste and preparation method thereof |
| CN106526156A (en) * | 2016-10-26 | 2017-03-22 | 王喜军 | Method for detecting, screening and identifying kidney-yang deficiency metabolism biomarkers |
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Application publication date: 20120801 |