CN104013789A - Traditional Chinese medicine preparation for relaxing bowel and expelling toxin and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for relaxing bowel and expelling toxin and preparation method thereof Download PDFInfo
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- CN104013789A CN104013789A CN201410228078.9A CN201410228078A CN104013789A CN 104013789 A CN104013789 A CN 104013789A CN 201410228078 A CN201410228078 A CN 201410228078A CN 104013789 A CN104013789 A CN 104013789A
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Abstract
The invention discloses a traditional Chinese medicine preparation for relaxing bowel and expelling toxin and a preparation method thereof. The traditional Chinese medicine comprises raw materials of an aloe dry powder, polygonum multiflorum, radix astragali and Radix Ophiopogonis. Raw materials includin polygonum multiflorum, radix astragali and Radix Ophiopogonis are leached for power process, the power is blended with the aloe dry powder, and the mixture is filled in capsules. The product is not only safe for administration, but also has significant disease control effect and low industrialized production cost.
Description
Technical field
The present invention relates to a kind of Chinese medicine with catharsis and toxin expelling and preparation method thereof, belong to medicine and field of health care food.
Background technology
In recent years, along with improving of medical research condition, utilize developmental research and the clinical significant progress that obtained of Chinese medicine constipation.Constipation is modal chronic digestible road symptom clinically, main manifestations be stool amount very little, too hard, discharge too difficulty, or merge some characteristic symptoms, as: firmly defecation, rectum is swollen sense, defecation are felt not to the utmost for a long time, even need to help defecation by maneuver.Clinically, general patient is after life conditioning and Drug therapy, and constipation symptom all can improve.Some patient is due to prolonged constipation, thereby makes foul smell decline, the clear YANG failing to ascend of body occur the symptoms such as abdominal distention, dizzy feeling of fullness in the head, the vexed belch of gastral cavity, loss of appetite, sleep disorder, susceptible to lose temper due to restlessness.Severe patient can cause that hemorrhoid, anal fissure even has blood in stool.And if the patient of constipation Overexertion in the time of defecation also can bring out the diseases such as hernia, hypertension, heart disease.Along with the change of social senilization, modern life rhythm and dietary habit, constipation becomes affect modern one of the important diseases of middle-aged and elderly people quality of life particularly day by day, actively develop clinically the treatment to constipation, not only be the hardship of energy constipation relieving, also can reduce the generation of other relevant disease, meaning is very great simultaneously.
Motherland's medical science thinks, " large intestine person, the organ in charge of transportation change and here.If " with age, weak, after being ill, eating and drinking without temperance, the quiet evil of happiness be moving etc., and factor causes large intestine conduction mistake department, the imbalance of intestinal internal organs ascending or descending movement of vital Qi, production of dryness-heat in the interior; impairment of body fluid consumption liquid, with bringing about the spread of body fluid's virtual loss, intestinal internal organs loses in making moist; the dry and astringent dryness accumulated in the stomach and intestine of intestinal, especially as " anhydrous sailing a boat " forms constipation.This disease belongs to deficiency in origin and excess in superficiality, and void is QI and blood and YIN fluid being insufficient, is knot in dryness accumulated in the stomach and intestine in fact.On principle for the treatment of, follow " treating both the principal and secondary aspects of a disease " principle, with benefiting QI and nourishing blood, nourishing YIN is promoted the production of body fluid and is moisturized, the toxin expelling that expels the heat-evil, and loosening bowel to relieve constipation is main.Therefore product of the present invention according to the traditional Chinese medical science Therapeutic Principle to constipation toxin expelling, screening has the raw material of effect of relaxing bowel effect, exploitation has taking convenience, the product of the present invention that safe and effective, toxic and side effects is little.Formula is made up of raw materials such as Aloe dry powder, Radix Polygoni Multiflori, the Radix Astragali, Radix Ophiopogonis, and its principles of formulating prescriptions are based on regulate yin-yang, are filled blood, protect body fluid, Shi Run leads, and with righting, and holds concurrently with eliminating evil, is used as to rush down with the body of its benefits, resides and rushes down in benefit, and reinforcing and reducing take into account.Whole formula meets the formula requirement of Chinese medicine and health food, and all medicines share, and can reach pleasant row stagnant, benefiting QI and nourishing blood, the efficacy effect of loosening bowel to relieve constipation toxin expelling.
Aloe is Liliaceae Aloe Aloe perennial evergreen meat herbaceous plant, originates in Mediterranean and south, Africa, and major part is grown in subtropical and tropical zones.There is cultivation on the ground such as China Guangdong, Hainan, Yunnan, Fujian.The history of worldwide applying Aloe has more than 4000 year, has recorded for a long time the medical value of Aloe in the supplement to the Herbal of China's the Tang Dynasty.Chinese medicine tradition is thought: Aloe is cold in nature, and bitter in the mouth is returned liver, stomach, large intestine channel, has relieving constipation by purgation, purging liver-heat, effect of the infantile malnutrition that disappears parasite killing, is used for the treatment of the diseases such as constipation with heat retention, liver-fire headache, conjunctival congestion infantile convulsion, infantile malnutrition with fever malnutrition due to parasitic infestation.So far, research is both at home and abroad found, the effective ingredient of Aloe is nearly more than 72 kinds, and wherein main bioactive ingredients has anthraquinones, mucopolysaccharide, polypeptide, aminoacid, organic acid, vitamin, mineral, chlorophyll, bioactive enzyme, protein, various trace elements etc.
radix Polygoni Multiflorifor Polygonaceae arsesmart Radix Polygoni Multiflori
polygonum thunbdried root.Medicinal Radix Polygoni Multiflori have Radix Polygoni Multiflori and Radix Polygoni Multiflori Preparata point, the two effect is variant: Radix Polygoni Multiflori bitter in the mouth, puckery, property are flat, has the merit of intestine moistening, removing toxic substances and preventing the attack (or recurrence) of malaria, for scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation, hyperlipidemia etc.Radix Polygoni Multiflori Preparata bitter in the mouth, puckery, warm in nature, has the effect of invigorating the liver and kidney, benefiting essence-blood, strengthening bone and muscle, black beard and hair, for Liver and kidney blood and essence asthenia, Light-headedness, early whitening of beard and hair, soreness of the waist and knees and seminal emission etc.The chemical composition of Radix Polygoni Multiflori mainly comprises: diphenylethylene, Anthraquinones, phospholipid etc.
The Radix Astragali (Astragalus membranaceus) is the root of herbaceos perennial Radix Astagali or Radix Astragali.It is sweet in flavor and warm in property, has tonifying Qi and lifting yang, benefit is defended the effects such as consolidating superficial resistance, inducing diuresis to remove edema, holder skin ulcer granulation promoting.Shennong's Herbal is classified as top grade, the Materia Medica of Decoction meaning Radix Astragali " soft taste are to call Central Region medicine also ".Modern pharmacology research shows that the Radix Astragali contains the plurality of active ingredients such as glycoside, polysaccharide, aminoacid and trace element, and cellular metabolism, nucleic acid metabolism, antibacterial and viral infection etc. are had to remarkable effect, and immune system, hormonal system etc. are all had to wide influence.
Chronic senile functional constipation (FC) is one of clinical common disease, the weak points such as although at present the treatment of constipation is had to a lot of methods, its curative effect is unstable, side effect large, drug resistance.Guan Ruijian etc. fail according to old people's function, large intestine conducts unable feature, adopts air making-up and spleen enlivening, the prescription astragali seu Hedysari Decoction oral liquid treatment senile (FC) of loosening bowel to relieve constipation, and by with the randomized controlled research of Maziren Wan group, inquire into the curative effect of astragali seu Hedysari Decoction in treatment senile (FC).Result: astragali seu Hedysari Decoction group can obviously improve the elimination factor of the 72h mark of Colonic transit, can obviously shorten infrequent defecation and defecation time-histories, to patient's defecation effort sensation, and stool character, rectum initial perception and rectum maximum tolerated dose are all improved effect.
Be the Liliaceae Ophiopogon plant dried root of Radix Ophiopogonis Radix Ophiopogonis, has YIN nourishing and the production of body fluid promoting, effect that lung moistening clears away heart-fire.Its sweet and slightly bitter taste, cold nature, GUIXIN, lung, stomach through, there is nourishing YIN and moistening the lung, reinforcing stomach reg fluid, effect of the relieving restlessness that clears away heart-fire, Traditional Chinese Medicine is mainly used to and lung, stomach, insufficiency of heart-YIN or thermal burn lung, stomach, disease that the heart-yin is relevant.The chemical composition of Radix Ophiopogonis is mainly saponins, flavonoid etc.The main pharmacological of Radix Ophiopogonis is effect of the impact on cardiovascular system, immunoregulatory effect, hypoglycemic effect, relieving constipation etc.
It is primary raw material that product of the present invention is selected Aloe dry powder, Radix Polygoni Multiflori, the Radix Astragali, the Radix Ophiopogonis that defecating feces excretion is very strong, the determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs prescription according to the traditional Chinese medical science to constipation.Aloe dry powder relieving constipation by purgation, purging liver-fire, is used for the treatment of the diseases such as constipation with heat retention, liver-fire headache, conjunctival congestion infantile convulsion, infantile malnutrition with fever malnutrition due to parasitic infestation; Radix Polygoni Multiflori removing toxic substances, eliminating carbuncle, loosening bowel to relieve constipation, for scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation etc.; Radix Astragali tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promotes the production of body fluid and nourishes blood, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation, Shennong's Herbal is classified as top grade, the Materia Medica of Decoction meaning Radix Astragali " soft taste are to call Central Region medicine also ".Radix Ophiopogonis YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire, loosening bowel to relieve constipation, Traditional Chinese Medicine is mainly used to and lung, stomach, insufficiency of heart-YIN or thermal burn lung, stomach, disease that the heart-yin is relevant.
Raw material of Chinese medicine has it from ancient times, very long, and its safety is approved.And each raw material all meets the requirement of Chinese Pharmacopoeia specification in formula, all within the scope of 2010 editions specified volumes of Chinese Pharmacopoeia, and without incompatibility.Be simultaneously again that State Food and Drug Administration ratifies spendable healthy food material, raw material of Chinese medicine mainly has safety for health food, the feature such as can eat for a long time, plays the effect of conditioning human body, auxiliary treatment.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine with catharsis and toxin expelling and preparation method thereof, this product is not only taken safety, have effect of significant disease preventing and treating, and industrial production cost is low.
For achieving the above object, the present invention adopts following technical scheme:
Have a Chinese medicine preparation for catharsis and toxin expelling, the composition of its raw material of Chinese medicine is by mass percentage: Aloe dry powder 29-31%, Radix Polygoni Multiflori 19-21%, Radix Astragali 22-24%, Radix Ophiopogonis 13-15%, starch 11-13%, magnesium stearate 0.5-1.5%.
There is a Chinese medicine preparation for catharsis and toxin expelling, the composition of its raw material and mass fraction: Aloe dry powder 30%, Radix Polygoni Multiflori 20%, the Radix Astragali 23%, Radix Ophiopogonis 14%, starch 12%, magnesium stearate 1.0%.
Have a preparation method for the Chinese medicine preparation of catharsis and toxin expelling, described preparation method comprises the steps:
(1) supplementary material requires and pre-treatment:
All meet raw material Aloe dry powder, Radix Polygoni Multiflori, the Radix Astragali, Radix Ophiopogonis " 2010 editions one of Chinese Pharmacopoeia " corresponding quality standard requirement; Purified water meets 2010 editions two purified water standard-requireds of Chinese Pharmacopoeia;
Raw material Radix Polygoni Multiflori, the Radix Astragali, Radix Ophiopogonis after the assay was approved, take formula ratio, for subsequent use; Raw material Aloe dry powder is through Co
60irradiation sterilization, dosage is: 6KGy; Supplementary product starch, magnesium stearate are after the assay was approved, for subsequent use;
(2) Radix Polygoni Multiflori, the Radix Astragali, raw material extraction powder process Radix Ophiopogonis:
Formula ratio Radix Polygoni Multiflori, the Radix Astragali, Radix Ophiopogonis are put in extraction pot, add the water extraction 2 times of 10 times of amounts, each 2 hours, extracting liquid filtering, merged twice filtrate, obtains water extraction liquid, for subsequent use; Medicinal residues discard, by water extraction liquid-0.08MPa, 70-80 DEG C reduce pressure, and is concentrated into relative density 1.20-1.25, temperature is 60 DEG C, obtains its concentrated solution; Concentrated solution is put in vacuum drying oven and carried out vacuum drying, and setting vacuum is-0.08MPa that 70 DEG C of baking temperatures, obtain dry extract; Dry extract is put in pulverizer and pulverized, cross 80 mesh sieves, obtain dry extract, for subsequent use;
(3) Aloe dry powder, starch, magnesium stearate are sieved:
The Aloe dry powder being up to the standards, starch, magnesium stearate are crossed respectively to 80 mesh sieves, take formula ratio, for subsequent use;
(4) mix:
Above-mentioned dry extract is put in mixer with formula ratio Aloe dry powder, starch, magnesium stearate mix homogeneously, no color differnece, obtain total mixed powder, incorporation time is 30-35 minute;
(5) filled capsules, polishing, subpackage:
By total mixed powder fully-automatic capsule filling machine filled capsules, loading amount specification is 0.45g/ grain, and the capsule inspection after filling, removes the inferior defective work of Denging; The polishing in capsule polisher of capsule after fill, picks out the underproof capsule of outward appearance in time; After polishing, be distributed into oral stable medicinal polythene bottle with high density, meet the standard-required of YBB00122002,60 every bottle;
(6) production environment sanitary cleaning level requires:
Production environment and management should meet GMP requirement, are dried, pulverize, sieve, the technique such as mixing, capsule-filling, polishing and subpackage all operates under the production clean area condition of 100,000 grades in production process, and other steps are carried out in general production area.
The invention has the advantages that:
Raw material of Chinese medicine of the present invention is by forming Aloe dry powder, Radix Polygoni Multiflori, the Radix Astragali, Radix Ophiopogonis, and it is the determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs prescription to constipation according to the traditional Chinese medical science.Raw material of Chinese medicine has it from ancient times, very long, and its safety is approved.Can eat for a long time, play the effect of conditioning human body, auxiliary treatment.In the present invention formula, be rich in bioactive ingredients have saponins material, barbaloin,, polysaccharide, aminoacid, organic acid, mineral, bioactive enzyme, protein, various trace elements etc.Human feeding trial result shows: after experimenter's test-meal with before test-meal, compare, defecation frequency obviously increases, and defecation condition and feces character are obviously improved (P<0.05).Point out product of the present invention to there is the effect of bowel relaxing functions.Experimenter all within normal range, does not observe obvious adverse reaction in every detection index such as hemogram, blood biochemistry during test-meal.Production Technology of the present invention has reached advanced international level.This technique convenient operation, can realize industrialization and produce continuously, therefore production cost is low.
Detailed description of the invention
embodiment 1
The composition of raw material of Chinese medicine is by mass percentage: Aloe dry powder 30%, Radix Polygoni Multiflori 20%, the Radix Astragali 23%, Radix Ophiopogonis 14%, starch 12%, magnesium stearate 1.0%.
Described preparation method comprises the steps:
(1) supplementary material requires and pre-treatment:
All meet raw material Aloe dry powder, Radix Polygoni Multiflori, the Radix Astragali, Radix Ophiopogonis " 2010 editions one of Chinese Pharmacopoeia " corresponding quality standard requirement; Purified water meets 2010 editions two purified water standard-requireds of Chinese Pharmacopoeia;
Raw material Radix Polygoni Multiflori, the Radix Astragali, Radix Ophiopogonis after the assay was approved, take formula ratio, for subsequent use; Raw material Aloe dry powder is through Co
60irradiation sterilization, dosage is: 6KGy; Supplementary product starch, magnesium stearate are after the assay was approved, for subsequent use;
(2) Radix Polygoni Multiflori, the Radix Astragali, raw material extraction powder process Radix Ophiopogonis:
Formula ratio Radix Polygoni Multiflori, the Radix Astragali, Radix Ophiopogonis are put in extraction pot, add the water extraction 2 times of 10 times of amounts, each 2 hours, extracting liquid filtering, merged twice filtrate, obtains water extraction liquid, for subsequent use; Medicinal residues discard, by water extraction liquid-0.08MPa, 70-80 DEG C reduce pressure, and is concentrated into relative density 1.20-1.25, temperature is 60 DEG C, obtains its concentrated solution; Concentrated solution is put in vacuum drying oven and carried out vacuum drying, and setting vacuum is-0.08MPa that 70 DEG C of baking temperatures, obtain dry extract; Dry extract is put in pulverizer and pulverized, cross 80 mesh sieves, obtain dry extract, for subsequent use;
(3) Aloe dry powder, starch, magnesium stearate are sieved:
The Aloe dry powder being up to the standards, starch, magnesium stearate are crossed respectively to 80 mesh sieves, take formula ratio, for subsequent use;
(4) mix:
Above-mentioned dry extract is put in mixer with formula ratio Aloe dry powder, starch, magnesium stearate mix homogeneously, no color differnece, obtain total mixed powder, incorporation time is 30 minutes;
(5) filled capsules, polishing, subpackage:
By total mixed powder fully-automatic capsule filling machine filled capsules, loading amount specification is 0.45g/ grain, and the capsule inspection after filling, removes the inferior defective work of Denging; The polishing in capsule polisher of capsule after fill, picks out the underproof capsule of outward appearance in time; After polishing, be distributed into oral stable medicinal polythene bottle with high density, meet the standard-required of YBB00122002,60 every bottle;
(6) production environment sanitary cleaning level requires:
Production environment and management should meet GMP requirement, are dried, pulverize, sieve, the technique such as mixing, capsule-filling, polishing and subpackage all operates under the production clean area condition of 100,000 grades in production process, and other steps are carried out in general production area.
embodiment 2
the composition of raw material of Chinese medicine is by mass percentage: Aloe dry powder 29%, Radix Polygoni Multiflori 22%, the Radix Astragali 23%, Radix Ophiopogonis 13%, starch 11%, magnesium stearate 1%.
Preparation method is as embodiment 1.
embodiment 3
Subjects extracts slight constipation patient 40 examples, and the age is 35-55 year; Poisoning constipation patient 40 examples, the age is 35-55 year; Severe constipation patient 40 examples, the age is 35-55 year.Its mild or moderate constipation person refers to 2-3 days defecations once, and moderate constipation refers to 3-6 days defecations once, and severe constipation refers to more than 7 days defecation once or dependence cathartic defecation, and once a day or two days once.
The Chinese medicine preparation for catharsis and toxin expelling that test method adopts the embodiment of the present invention 1 to provide is treated constipation patient.Slight constipation patient is taken said preparation 7 days, within first 3 days, takes 6,3 of 4 day afterwards every days, directly swallows.Moderate constipation patient is taken preparation 7 days, and take 12 first 3 day every day, and take 64 day afterwards every day, directly swallows.Severe constipation patient is taken said preparation 7 days, takes 18 first three day every day, 9 of 4 day afterwards every days, directly swallows.
Test effect: slight constipation patient, in first 3 days that take preparation, is arranged soft partially loose stool every day 2 to 3 times, and constipation situation significantly improves, and after decrement was taken in 4-7 days, arranges soft stool every day 1 to 2 time.Moderate constipation patient, taking in first 3 days of preparation, wherein has 33 routine patients to arrange soft partially loose stool every day 2-3 time, and 7 routine patients arrange soft stool every day 1-2 time, and after 4-7 days decrements, 40 routine patients arrange soft stool whole every days 1-2 time.Severe constipation patient is taking in first 3 days of preparation, wherein there are 16 routine patients to arrange soft partially loose stool every day 2-3 time, 20 routine patients arrange soft stool every day 1-2 time, in all the other 4 routine patients 3 days, defecation once, constipation situation also makes moderate progress, after within 4-7 days, decrement is taken, 38 routine patients arrange 1-2 time whole every days.All constipation patient in various degree has all obtained effective treatment.
The foregoing is only preferred embodiment of the present invention, all equalizations of doing according to the present patent application the scope of the claims change and modify, and all should belong to covering scope of the present invention.
Claims (3)
1. a Chinese medicine preparation with catharsis and toxin expelling, is characterized in that: the composition of its raw material of Chinese medicine is by mass percentage: Aloe dry powder 29-31%, Radix Polygoni Multiflori 19-21%, Radix Astragali 22-24%, Radix Ophiopogonis 13-15%, starch 11-13%, magnesium stearate 0.5-1.5%.
2. a kind of Chinese medicine preparation with catharsis and toxin expelling according to claim 1, is characterized in that: the composition of its raw material and mass fraction: Aloe dry powder 30%, Radix Polygoni Multiflori 20%, the Radix Astragali 23%, Radix Ophiopogonis 14%, starch 12%, magnesium stearate 1.0%.
3. a preparation method for a kind of Chinese medicine preparation with catharsis and toxin expelling as claimed in claim 1 or 2, is characterized in that: described preparation method comprises the steps:
(1) supplementary material requires and pre-treatment:
All meet raw material Aloe dry powder, Radix Polygoni Multiflori, the Radix Astragali, Radix Ophiopogonis " 2010 editions one of Chinese Pharmacopoeia " corresponding quality standard requirement; Purified water meets 2010 editions two purified water standard-requireds of Chinese Pharmacopoeia;
Raw material Radix Polygoni Multiflori, the Radix Astragali, Radix Ophiopogonis after the assay was approved, take formula ratio, for subsequent use; Raw material Aloe dry powder is through Co
60irradiation sterilization, dosage is: 6KGy; Supplementary product starch, magnesium stearate are after the assay was approved, for subsequent use;
(2) Radix Polygoni Multiflori, the Radix Astragali, raw material extraction powder process Radix Ophiopogonis:
Formula ratio Radix Polygoni Multiflori, the Radix Astragali, Radix Ophiopogonis are put in extraction pot, add the water extraction 2 times of 10 times of amounts, each 2 hours, extracting liquid filtering, merged twice filtrate, obtains water extraction liquid, for subsequent use; Medicinal residues discard, by water extraction liquid-0.08MPa, 70-80 DEG C reduce pressure, and is concentrated into relative density 1.20-1.25, temperature is 60 DEG C, obtains its concentrated solution; Concentrated solution is put in vacuum drying oven and carried out vacuum drying, and setting vacuum is-0.08MPa that 70 DEG C of baking temperatures, obtain dry extract; Dry extract is put in pulverizer and pulverized, cross 80 mesh sieves, obtain dry extract, for subsequent use;
(3) Aloe dry powder, starch, magnesium stearate are sieved:
The Aloe dry powder being up to the standards, starch, magnesium stearate are crossed respectively to 80 mesh sieves, take formula ratio, for subsequent use;
(4) mix:
Above-mentioned dry extract is put in mixer with formula ratio Aloe dry powder, starch, magnesium stearate mix homogeneously, no color differnece, obtain total mixed powder, incorporation time is 30-35 minute;
(5) filled capsules, polishing, subpackage:
By total mixed powder fully-automatic capsule filling machine filled capsules, loading amount specification is 0.45g/ grain, and the capsule inspection after filling, removes the inferior defective work of Denging; The polishing in capsule polisher of capsule after fill, picks out the underproof capsule of outward appearance in time; After polishing, be distributed into oral stable medicinal polythene bottle with high density, meet the standard-required of YBB00122002,60 every bottle;
(6) production environment sanitary cleaning level requires:
Production environment and management should meet GMP requirement, are dried, pulverize, sieve, the technique such as mixing, capsule-filling, polishing and subpackage all operates under the production clean area condition of 100,000 grades in production process, and other steps are carried out in general production area.
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Cited By (5)
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| CN106074977A (en) * | 2016-07-27 | 2016-11-09 | 张志杰 | A kind of Chinese medicine oral liquid of YIN nourishing relieving constipation |
| CN106075045A (en) * | 2016-07-27 | 2016-11-09 | 张志杰 | A kind of Chinese medicine composition of catharsis and toxin expelling |
| CN107440118A (en) * | 2017-08-16 | 2017-12-08 | 河南树铭药业有限公司 | A kind of health food with defecating feces excretion and preparation method thereof |
| CN109939175A (en) * | 2019-03-21 | 2019-06-28 | 清华德人西安幸福制药有限公司 | Chinese medicine composition, preparation method and the application of relax bowel and defecation |
| CN113952412A (en) * | 2021-12-10 | 2022-01-21 | 安发（福建）生物科技有限公司 | Traditional Chinese medicine composition for relaxing bowels and expelling toxin and preparation method thereof |
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| CN1579449A (en) * | 2003-08-08 | 2005-02-16 | 柴雪琼 | Health-care skin-care food |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106074977A (en) * | 2016-07-27 | 2016-11-09 | 张志杰 | A kind of Chinese medicine oral liquid of YIN nourishing relieving constipation |
| CN106075045A (en) * | 2016-07-27 | 2016-11-09 | 张志杰 | A kind of Chinese medicine composition of catharsis and toxin expelling |
| CN107440118A (en) * | 2017-08-16 | 2017-12-08 | 河南树铭药业有限公司 | A kind of health food with defecating feces excretion and preparation method thereof |
| CN109939175A (en) * | 2019-03-21 | 2019-06-28 | 清华德人西安幸福制药有限公司 | Chinese medicine composition, preparation method and the application of relax bowel and defecation |
| CN113952412A (en) * | 2021-12-10 | 2022-01-21 | 安发（福建）生物科技有限公司 | Traditional Chinese medicine composition for relaxing bowels and expelling toxin and preparation method thereof |
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