CN105920541A - 一种治疗花斑癣的中药组合物 - Google Patents

一种治疗花斑癣的中药组合物 Download PDF

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CN105920541A
CN105920541A CN201610468556.2A CN201610468556A CN105920541A CN 105920541 A CN105920541 A CN 105920541A CN 201610468556 A CN201610468556 A CN 201610468556A CN 105920541 A CN105920541 A CN 105920541A
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丁常燕
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Abstract

本发明公开了一种治疗花斑癣的中药组合物，其中药原料及重量份配比为：金银花10‑30份，珍珠莲10‑20份，黄芩10‑20份，丹参5‑15份，玄参10‑20份，薄荷10‑20份，夏枯草10‑20份，虎杖10‑20份，黄连5‑15份，郁金10‑20份，川芎10‑20份，苍耳子5‑15份，太子参10‑20份，大青叶10‑20份，吊干麻10‑20份，青蒿5‑15份，贯众10‑20份，龙船花10‑20份，大黄10‑20份，凤仙花5‑15份，柳叶10‑20份，铜锤玉带草10‑20份，地肤子5‑15份，甘草5‑15份。其具有清热解毒、祛风除湿、活血止痒、益气健脾的功效，治疗花斑癣疗效显著，作用可靠。

Description

一种 治疗花斑癣的中药组合物
技术领域
本发明涉及一种传统草药的未确定结构的医用配制品，尤其是一种治疗花斑癣的中药组合物。
背景技术
花斑癣是由马拉色菌感染表皮角质层引起的一种浅表真菌病，发生于成人，多与夏季出汗有关，好发于躯干及上肢等汗腺丰富的部位，故俗称汗斑。本病自觉症状轻微，常在炎热季节发病或加重。损害一般为粟粒、黄豆至蚕豆大的圆形或类圆形斑疹，表面覆以细薄的糠秕状鳞屑。初起皮疹色泽较深呈淡褐色，以后可以出现色素减退斑，由于新旧皮损混合存在而呈花斑状。目前，临床上治疗本病主要为角质剥脱剂和杀菌剂两类，如硫化硒、硫代硫酸钠等，虽然具有一定疗效，但药物的副作用会对人体产生很大的伤害，不能根治。
中医认为，花斑癣多因素体热盛，风湿相侵，留于腠理而成，亦有因汗衣湿溻，淹渍肌肤，复受日曝，暑湿浸滞毛窍所致。
根据中医理论，针对花斑癣的发病机理，以祛风除湿、活血止痒为治则，进行辩证配伍组方，以达到标本兼治的目的。
发明内容
为了克服现有技术中采用角质剥脱剂、杀菌剂类药物治疗花斑癣存在副作用大的不足，本发明提供一种配制方便、药源广、疗效显著、作用可靠、无副作用的治疗花斑癣的中药组合物。
本发明解决其技术问题所采用的技术方案是：一种治疗花斑癣的中药组合物，其特征在于：其中药原料及重量份配比为：金银花10-30份，珍珠莲10-20份，黄芩10-20份，丹参5-15份，玄参10-20份，薄荷10-20份，夏枯草10-20份，虎杖10-20份，黄连5-15份，郁金10-20份，川芎10-20份，苍耳子5-15份，太子参10-20份，大青叶10-20份，吊干麻10-20份，青蒿5-15份，贯众10-20份，龙船花10-20份，大黄10-20份，凤仙花5-15份，柳叶10-20份，铜锤玉带草10-20份，地肤子5-15份，甘草5-15份。
本发明的优选技术方案是：一种治疗花斑癣的中药组合物，其特征在于：其中药原料及重量份配比为：金银花20份，珍珠莲15份，黄芩15份，丹参10份，玄参15份，薄荷15份，夏枯草15份，虎杖15份，黄连10份，郁金15份，川芎15份，苍耳子10份，太子参15份，大青叶15份，吊干麻15份，青蒿10份，贯众15份，龙船花15份，大黄15份，凤仙花10份，柳叶15份，铜锤玉带草15份，地肤子10份，甘草10份。
本发明中药组合物是在传统中医理论和临床经验指导下，精选药物组方。本发明中药组合物中：金银花具有清热解毒、凉散风热的功效；珍珠莲具有祛风除湿、消肿止痛、解毒杀虫的功效；黄芩具有清热燥湿、泻火解毒、止血安胎的功效；丹参具有活血调经、祛瘀止痛、凉血消痈、清心除烦、养血安神的功效；玄参具有凉血滋阴、泻火解毒的功效；薄荷具有疏散风热、清利解毒、疏肝解郁的功效；夏枯草具有清肝明目、清热利尿、散结消肿的功效；虎杖具有活血散瘀、祛风通络、清热利湿、解毒、止咳化痰的功效；黄连具有清热燥湿、泻火解毒的功效；郁金具有行气化瘀、清心解郁的功效；川芎具有活血祛瘀、行气开郁、祛风止痛的功效；苍耳子具有散风寒、通鼻窍、祛风湿、止痒的功效；太子参具有益气健脾、生津润肺的功效；大青叶具有清热解毒、凉血消斑的功效；吊干麻具有清热利湿、杀虫的功效；青蒿具有清透虚热、凉血除蒸、截疟的功效；贯众具有清热解毒、凉血止血、杀虫的功效；龙船花具有清热凉血、散瘀止痛的功效；大黄具有泻火消积、清热解毒、凉血止血、祛瘀止咳的功效；凤仙花具有祛风除湿、活血止痛、解毒杀虫的功效；柳叶具有清热利尿、解毒透疹、平肝止痛的功效；铜锤玉带草具有祛风除湿、活血解毒的功效；地肤子具有清热利湿、祛风止痒的功效；甘草具有补脾益气、清热解毒、祛痰止咳、调和诸药的功效。本发明组合物中的药物组分经辩证配伍，在作用上相辅相成，具有协同作用，共奏清热解毒、祛风除湿、活血止痒、益气健脾之功效，对花斑癣达到标本兼治的目的。
本发明组合物的组分均采用天然的中药原料，其配制简便、药源广、成本低。其遵循中医的处方用药原则，各种组分药物采用水煎服用。经临床应用验证，其疗效显著，作用可靠，药性平和，未出现毒副作用，总有效率91.9%，治愈率达64.9%。
具体实施方式
下面结合实施例对本发明做进一步说明。
实施例1
一种治疗花斑癣的中药组合物，其中药原料及重量配比为：金银花20g，珍珠莲15g，黄芩15g，丹参10g，玄参15g，薄荷15g，夏枯草15g，虎杖15g，黄连10g，郁金15g，川芎15g，苍耳子10g，太子参15g，大青叶15g，吊干麻15g，青蒿10g，贯众15g，龙船花15g，大黄15g，凤仙花10g，柳叶15g，铜锤玉带草15g，地肤子10g，甘草10g。
实施例2
一种治疗花斑癣的中药组合物，其中药原料及重量配比为：金银花30g，珍珠莲10g，黄芩20g，丹参5g，玄参20g，薄荷10g，夏枯草20g，虎杖10g，黄连15g，郁金10g，川芎20g，苍耳子5g，太子参20g，大青叶10g，吊干麻20g，青蒿5g，贯众20g，龙船花10g，大黄20g，凤仙花5g，柳叶20g，铜锤玉带草10g，地肤子15g，甘草5g。
实施例3
一种治疗花斑癣的中药组合物，其中药原料及重量配比为：金银花10g，珍珠莲20g，黄芩10g，丹参15g，玄参10g，薄荷20g，夏枯草10g，虎杖20g，黄连5g，郁金20g，川芎10g，苍耳子15g，太子参10g，大青叶20g，吊干麻10g，青蒿15g，贯众10g，龙船花20g，大黄10g，凤仙花15g，柳叶10g，铜锤玉带草20g，地肤子5g，甘草15g。
实施例4
一种治疗花斑癣的中药组合物，其中药原料及重量配比为：金银花23g，珍珠莲12g，黄芩18g，丹参7g，玄参18g，薄荷12g，夏枯草18g，虎杖12g，黄连13g，郁金12g，川芎18g，苍耳子7g，太子参18g，大青叶12g，吊干麻18g，青蒿7g，贯众18g，龙船花12g，大黄18g，凤仙花7g，柳叶18g，铜锤玉带草12g，地肤子13g，甘草7g。
实施例5
一种治疗花斑癣的中药组合物，其中药原料及重量配比为：金银花17g，珍珠莲18g，黄芩12g，丹参13g，玄参12g，薄荷18g，夏枯草12g，虎杖18g，黄连7g，郁金18g，川芎12g，苍耳子13g，太子参12g，大青叶18g，吊干麻12g，青蒿13g，贯众12g，龙船花18g，大黄12g，凤仙花13g，柳叶12g，铜锤玉带草18g，地肤子7g，甘草13g。
本发明实施例中的中药组合物按常规的水煎法制取药剂。具体方法如下：将组方的中药原料放入容器中，加冷水漫过药面，浸泡15～20分钟，再加水没过药面约8厘米，进行第一次煎煮，未沸前采用武火煎煮，沸后用文火煎煮20～30分钟；第二次煎煮，加水没过药面约7厘米，水沸后煎煮15～20分钟。两次煎煮去渣取汁，合并。
本发明以实施例1所给出的一种治疗花斑癣的中药组合物，做临床疗效总结如下：
一、一般性资料：本发明中药组合物应用于临床观察病例74例，其中男38例，女36例，年龄20～65岁。
二、诊断标准：
1、皮疹好发于胸背部、颈部和四肢近端等部位；
2、常于夏季发病或加重，冬季好转或消退；
3、皮疹为圆形或不规则形的黄豆大或更大的斑疹，境界清楚，呈淡白色、淡红色、淡褐色甚至黑色，其上附着有糠状的微发亮的细小鳞屑；皮疹可逐渐扩大增多，并可互相融合成大片状，但边缘清楚；
4、一般无自觉症状，或有轻度痒感；
5、必要时可作真菌直接镜检，以进一步明确诊断。
三、用法用量：临床应用时，一天一剂，水煎两遍取汁约300ml，分早、晚两次温热服用，六天为一疗程。服药期间忌食生冷、辛辣之物。
四、疗效标准：
1、治愈：花斑癣块全部消失；
2、好转：花斑癣块消失50％面积；
3、未愈：花斑癣块尚存20％面积。
五、治疗效果：该临床观察病例中，服药3-12个疗程，治愈48例，好转20例，未愈6例。治疗期间未发生毒副作用。
六、典型病例：
病例1：周某，男，60岁。患者自述：初起时胸部出现淡红色黄豆大小的皮疹，微痒，并未重视，后逐渐扩大增多至四肢，夏季尤为严重。服用本发明的中药组合物制备的药剂3个疗程后，自觉皮损消退许多；继续服用4个疗程，症状消失，治愈。随访半年未复发。
病例2：孙某，女，47岁。患者自述：已有2年花斑癣病史，圆形斑疹遍布四肢及面部，日晒或多汗后伴有瘙痒感。期间使用过很多抗菌剂等西药治疗，病情总是反复。服用本发明的中药组合物制备的药剂6个疗程，皮损明显消退，瘙痒感减轻；继续服用3个疗程后，各症状消失，治愈。

Claims (2)

1.一种治疗花斑癣的中药组合物，其特征在于：其中药原料及重量份配比为：金银花10-30份，珍珠莲10-20份，黄芩10-20份，丹参5-15份，玄参10-20份，薄荷10-20份，夏枯草10-20份，虎杖10-20份，黄连5-15份，郁金10-20份，川芎10-20份，苍耳子5-15份，太子参10-20份，大青叶10-20份，吊干麻10-20份，青蒿5-15份，贯众10-20份，龙船花10-20份，大黄10-20份，凤仙花5-15份，柳叶10-20份，铜锤玉带草10-20份，地肤子5-15份，甘草5-15份。
2.根据权利要求1所述的一种治疗花斑癣的中药组合物，其特征在于：其中药原料及重量份配比为：金银花20份，珍珠莲15份，黄芩15份，丹参10份，玄参15份，薄荷15份，夏枯草15份，虎杖15份，黄连10份，郁金15份，川芎15份，苍耳子10份，太子参15份，大青叶15份，吊干麻15份，青蒿10份，贯众15份，龙船花15份，大黄15份，凤仙花10份，柳叶15份，铜锤玉带草15份，地肤子10份，甘草10份。
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