CN105920295A - Traditional Chinese medicine composition with effects of moistening throat and relieving sore throat and its preparation method and use - Google Patents
Traditional Chinese medicine composition with effects of moistening throat and relieving sore throat and its preparation method and use Download PDFInfo
- Publication number
- CN105920295A CN105920295A CN201610274517.9A CN201610274517A CN105920295A CN 105920295 A CN105920295 A CN 105920295A CN 201610274517 A CN201610274517 A CN 201610274517A CN 105920295 A CN105920295 A CN 105920295A
- Authority
- CN
- China
- Prior art keywords
- parts
- weight
- chinese medicine
- medicine composition
- radix
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 45
- 239000000203 mixture Substances 0.000 title claims abstract description 33
- 201000007100 Pharyngitis Diseases 0.000 title claims abstract description 29
- 206010068319 Oropharyngeal pain Diseases 0.000 title claims abstract description 28
- 230000000694 effects Effects 0.000 title claims abstract description 28
- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- 238000000605 extraction Methods 0.000 claims abstract description 14
- 239000000284 extract Substances 0.000 claims abstract description 11
- 229940079593 drug Drugs 0.000 claims abstract description 6
- 230000036541 health Effects 0.000 claims abstract description 5
- 241000756943 Codonopsis Species 0.000 claims description 14
- 239000009609 fructus phyllanthi Substances 0.000 claims description 14
- 239000000341 volatile oil Substances 0.000 claims description 12
- 239000002671 adjuvant Substances 0.000 claims description 7
- 239000000706 filtrate Substances 0.000 claims description 6
- 239000008187 granular material Substances 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 6
- 239000012567 medical material Substances 0.000 claims description 6
- 239000000843 powder Substances 0.000 claims description 6
- 239000002994 raw material Substances 0.000 claims description 6
- 238000001256 steam distillation Methods 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims description 4
- 240000002853 Nelumbo nucifera Species 0.000 claims description 4
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims description 4
- 239000000047 product Substances 0.000 claims description 4
- 201000010099 disease Diseases 0.000 claims description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 2
- 238000002474 experimental method Methods 0.000 abstract description 5
- 239000002552 dosage form Substances 0.000 abstract description 2
- 239000012535 impurity Substances 0.000 abstract description 2
- 244000119298 Emblica officinalis Species 0.000 abstract 1
- 235000015489 Emblica officinalis Nutrition 0.000 abstract 1
- 241000605372 Fritillaria Species 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 235000017443 Hedysarum boreale Nutrition 0.000 abstract 1
- 235000007858 Hedysarum occidentale Nutrition 0.000 abstract 1
- 235000006679 Mentha X verticillata Nutrition 0.000 abstract 1
- 235000002899 Mentha suaveolens Nutrition 0.000 abstract 1
- 235000001636 Mentha x rotundifolia Nutrition 0.000 abstract 1
- 235000006753 Platycodon grandiflorum Nutrition 0.000 abstract 1
- 240000003582 Platycodon grandiflorus Species 0.000 abstract 1
- 241000405414 Rehmannia Species 0.000 abstract 1
- 239000001947 glycyrrhiza glabra rhizome/root Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 9
- 208000024891 symptom Diseases 0.000 description 8
- 206010011224 Cough Diseases 0.000 description 4
- 230000006872 improvement Effects 0.000 description 4
- 230000007812 deficiency Effects 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 239000002893 slag Substances 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000013642 negative control Substances 0.000 description 2
- 239000000419 plant extract Substances 0.000 description 2
- 230000002685 pulmonary effect Effects 0.000 description 2
- 230000000391 smoking effect Effects 0.000 description 2
- 206010013952 Dysphonia Diseases 0.000 description 1
- 208000010473 Hoarseness Diseases 0.000 description 1
- 208000018569 Respiratory Tract disease Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 210000000867 larynx Anatomy 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8966—Fritillaria, e.g. checker lily or mission bells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/346—Platycodon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine composition with effects of moistening throat and relieving sore throat and its preparation method and use. The traditional Chinese medicine composition is prepared from 15-20 parts by weight of Zhejiang fritillaria bulb, 10-15 parts by weight of phyllanthus emblica, 10-15 parts by weight of dried orange peel, 10-15 parts by weight of pilose asiabell root, 5-10 parts by weight of unprocessed rehmannia root, 5-10 parts by weight of balloonflower root, 5-10 parts by weight of mint and 5-10 parts by weight of licorice root. A lot of experiments screen pure natural Chinese medicinal herb extract with effects of moistening throat and relieving sore throat. The traditional Chinese medicine composition can effectively improve throat discomfort, has a scientific and reasonable formula, is environmentally friendly and safe and has a wide application range. The preparation method comprises the optimal extraction processes screened by a lot of experiments according to drug active components and physical and chemical properties. The traditional Chinese medicine composition has high extract active component content, less impurities, high safety and reliable curative effects, can be processed to form needed drug or health product dosage forms according to actual demands and is convenient for eating.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, a kind of Chinese medicine composition with the sore-throat relieving effect that wets one's whistle and preparation method thereof
And application.
Background technology
Along with environmental pollution, and smoking and second hand smoking, the number drunk increase, and long-term excessive throat, stay up late etc. unhealthy
Life style, the situation of the health risk such as throat discomfort, chronic pharyngitis and respiratory tract disease frequently occurs, common bottleneck throat
Swell and ache, be dried, block, hoarseness, the situation such as discomfort, cough of swallowing are valued by the people all the more.The most not
Effective in cure reliably, medicine in good taste.
Therefore, necessary on the basis of prior art, design research and development one has a sore-throat relieving that well wets one's whistle, relieving cough and moistening lung,
Taste is good, the Chinese medicine composition of green safety.
Summary of the invention
Goal of the invention: the invention aims to overcome the deficiencies in the prior art, it is provided that one has the sore-throat relieving that well wets one's whistle,
Relieving cough and moistening lung, taste is good, the Chinese medicine composition of green safety.Another object of the present invention is to provide the preparation of this Chinese medicine composition
Method.
Technical scheme, in order to realize object above, the technical scheme that the present invention takes is:
A kind of Chinese medicine composition with the sore-throat relieving effect that wets one's whistle, it comprises the raw material of following parts by weight:
Bulbus Fritillariae Thunbergii 15-20 part, Fructus Phyllanthi 10-15 part, Pericarpium Citri Reticulatae 10-15 part, Radix Codonopsis 10-15 part, Radix Rehmanniae 5-10 part, Radix Platycodonis
5-10 part, Herba Menthae 5-10 part, Radix Glycyrrhizae 5-10 part.
Preferably, the above-described Chinese medicine composition with the sore-throat relieving effect that wets one's whistle, it comprises the former of following parts by weight
Material:
Bulbus Fritillariae Thunbergii 15 parts, Fructus Phyllanthi 10 parts, Pericarpium Citri Reticulatae 10 parts, Radix Codonopsis 10 parts, 5 parts of the Radix Rehmanniae, Radix Platycodonis 5 parts, Herba Menthae 5 parts,
5 parts of Radix Glycyrrhizae.
Preferably, the above-described Chinese medicine composition with the sore-throat relieving effect that wets one's whistle, it comprises the former of following parts by weight
Material:
Bulbus Fritillariae Thunbergii 20 parts, Fructus Phyllanthi 15 parts, Pericarpium Citri Reticulatae 15 parts, Radix Codonopsis 15 parts, 10 parts of the Radix Rehmanniae, Radix Platycodonis 10 parts, Herba Menthae 10
Part, 10 parts of Radix Glycyrrhizae.
The preparation method of the Chinese medicine composition with the sore-throat relieving effect that wets one's whistle that the present invention provides, comprises the following steps:
(1) take Herba Menthae by weight, use extraction by steam distillation, isolated volatile oil and Herba Menthae medicinal residues；
(2) Fructus Phyllanthi is taken by weight, Pericarpium Citri Reticulatae, Radix Codonopsis, the Radix Rehmanniae, Radix Platycodonis, Radix Glycyrrhizae and step (1) Herba Menthae medicinal residues, add
The soak by water 1 of medical material weight 8～10 times amount volume～3 times, each 1～2 hour, filter and remove residue, united extraction liquid, filtrate concentrated
Obtain extractum；
(3) taking step (2) and extract the extractum that obtains, add Bulbus Fritillariae Thunbergii fine powder, be subsequently adding that step (1) prepares is thin
Lotus volatile oil, is subsequently adding adjuvant, granule processed, is dried.
Preferably, the preparation method of the above-described Chinese medicine composition with the sore-throat relieving effect that wets one's whistle, it includes following step
Rapid:
(1) take Herba Menthae by weight, use extraction by steam distillation, isolated volatile oil and Herba Menthae medicinal residues；
(2) Fructus Phyllanthi is taken by weight, Pericarpium Citri Reticulatae, Radix Codonopsis, the Radix Rehmanniae, Radix Platycodonis, Radix Glycyrrhizae and step (1) Herba Menthae medicinal residues, add
The soak by water of medical material weight 10 times amount volume 2 times, each 1 hour, filter and remove residue, united extraction liquid, filtrate was concentrated to give extractum；
(3) taking step (2) and extract the extractum that obtains, add Bulbus Fritillariae Thunbergii fine powder, be subsequently adding that step (1) prepares is thin
Lotus volatile oil, is subsequently adding adjuvant, granule processed, is dried.
Of the present invention have the Chinese medicine composition of the sore-throat relieving effect that wets one's whistle in preparation prevents and treats medicine or the health product of pharyngolaryngitis disease
Application.
The present invention is directed to deficiency of the prior art, screen prescription, eight taste medicines in side by great many of experiments, complement each other, Xiang get
Benefit is evident, and wet one's whistle sore-throat relieving, relieving cough and moistening lung, and excellent in taste, is easily accepted.
Beneficial effect: compared to the prior art the Chinese medicine composition with the sore-throat relieving effect that wets one's whistle that the present invention provides, has following excellent
Point:
The present invention, according to the deficiency of prior art larynx moistening candy, is filtered out by great many of experiments in the pure natural with the sore-throat relieving effect that wets one's whistle
Medicine plant extract, the Chinese medicine composition that the present invention provides can be effectively improved the symptoms such as throat discomfort, and whole scientific formulation is reasonable,
Green safety, and the scope of application is widely.
The preparation method of the Chinese medicine composition with the sore-throat relieving effect that wets one's whistle that the present invention provides, according to active component and the reason of each flavour of a drug
Changing character, filter out optimal extraction process by great many of experiments, the extract active component content prepared is high, and impurity is few,
Safety is high, and curative effect is reliable.And can be prepared as according to actual needs needing the medicine of dosage form or health product, conveniently take.
Detailed description of the invention
Be further elucidated with the present invention below in conjunction with specific embodiment, it should be understood that these embodiments be merely to illustrate the present invention rather than
Limit the scope of the present invention, after having read the present invention, those skilled in the art's amendment to the various equivalent form of values of the present invention
All fall within the application claims limited range.
Embodiment 1
1, a kind of Chinese medicine composition with the sore-throat relieving effect that wets one's whistle, it is made up of the raw material of following parts by weight:
Bulbus Fritillariae Thunbergii 15 parts, Fructus Phyllanthi 10 parts, Pericarpium Citri Reticulatae 10 parts, Radix Codonopsis 10 parts, 5 parts of the Radix Rehmanniae, Radix Platycodonis 5 parts, Herba Menthae 5 parts,
5 parts of Radix Glycyrrhizae.
2, there is the preparation method of the Chinese medicine composition of the sore-throat relieving effect that wets one's whistle: it comprises the following steps:
(1) take thin 5 parts by weight, use extraction by steam distillation 2 hours, isolated volatile oil and Herba Menthae medicine
Slag；
(2) Fructus Phyllanthi 10 parts, Pericarpium Citri Reticulatae 10 parts, Radix Codonopsis 10 parts, 5 parts of the Radix Rehmanniae, Radix Platycodonis 5 parts, Radix Glycyrrhizae 5 are taken by weight
Part and step (1) Herba Menthae medicinal residues, the soak by water of addition medical material weight 10 times amount volume 2 times, each 1 hour, filter and remove residue,
United extraction liquid, filtrate is concentrated to give extractum；
(3) take step (2) and extract the extractum obtained, add Bulbus Fritillariae Thunbergii fine powder 15 parts, be subsequently adding step (1) and prepare
Herba Menthae Haplocalycis volatile oil, be subsequently adding adjuvant, granule processed, be dried, bag subpackage, 5 grams/bag.
Embodiment 2
1, a kind of Chinese medicine composition with the sore-throat relieving effect that wets one's whistle: it is made up of the raw material of following parts by weight:
Bulbus Fritillariae Thunbergii 20 parts, Fructus Phyllanthi 15 parts, Pericarpium Citri Reticulatae 15 parts, Radix Codonopsis 15 parts, 10 parts of the Radix Rehmanniae, Radix Platycodonis 10 parts, Herba Menthae 10
Part, 10 parts of Radix Glycyrrhizae.
2, there is the preparation method of the Chinese medicine composition of the sore-throat relieving effect that wets one's whistle: it comprises the following steps:
(1) take thin 10 parts by weight, use extraction by steam distillation 3 hours, isolated volatile oil and Herba Menthae medicine
Slag；
(2) Fructus Phyllanthi 15 parts, Pericarpium Citri Reticulatae 15 parts, Radix Codonopsis 15 parts, 10 parts of the Radix Rehmanniae, Radix Platycodonis 10 parts, Radix Glycyrrhizae are taken by weight
10 parts and step (1) Herba Menthae medicinal residues, the soak by water of addition medical material weight 8 times amount volume 2 times, each 2 hours, cross and filter off
Slag, united extraction liquid, filtrate is concentrated to give extractum；
(3) take step (2) and extract the extractum obtained, add Bulbus Fritillariae Thunbergii fine powder 20 parts, be subsequently adding step (1) and prepare
Herba Menthae Haplocalycis volatile oil, be subsequently adding adjuvant, granule processed, be dried, bag subpackage, 5 grams/bag.
Embodiment 3 example effects
Throat discomfort patient is carried out clinical treatment research, determines the effectiveness of this product.
1, case selection: observing 200 examples and suffer from chronic pharyngolaryngitis, pulmonary discomfort patient, randomized, double-blind is divided into two groups: test 1 group
70 examples, male 38 example, women 32 example, 36.8 years old mean age；Test 2 group of 70 example, male 39 example, women 31 example,
36.4 years old mean age；Negative control group 60 example, male 34 example, women 26 example, 36.7 years old mean age.
2, Therapeutic Method:
Test group: test 1 group and take and use the made Chinese medicine extract of example 1, test 2 groups take employing example 2 made in
Medicament extract, the most daily 3 times, each 5 grams.
Negative control group: not adding the adjuvant group of Chinese medicinal plant extract, profile, taste are similar to test group, dose and test
Organize identical.
Evaluation criteria:
Effective: after taking 7 days, symptom has clear improvement, after 2 weeks, symptom disappears substantially.
Effective: after taking 7 days, symptom makes moderate progress, after 2 weeks, major part symptom alleviates or disappears.
Invalid: to take rear symptom without significant change or improvement.
3, result: as shown in table 1:
Table 1 test group and matched group evaluation result
* P < 0.01 is compared with matched group；
By test result indicate that above, tested crowd does not has significant discomfort symptom at the Chinese medicine composition taking present invention offer,
And throat and pulmonary's malaise symptoms can be effectively improved, there were significant differences compared with matched group for total effective rate, and result shows the present invention
The Chinese medicine composition provided has the sore-throat relieving effect that significantly wets one's whistle, and security performance is high.
The above is only the preferred embodiment of the present invention, it is noted that for those skilled in the art,
Under the premise without departing from the principles of the invention, it is also possible to make some improvements and modifications, these improvements and modifications also should be regarded as this
Bright protection domain.
Claims (6)
1. a Chinese medicine composition with the sore-throat relieving effect that wets one's whistle, it is characterised in that it comprises the raw material of following parts by weight:
Bulbus Fritillariae Thunbergii 15-20 part, Fructus Phyllanthi 10-15 part, Pericarpium Citri Reticulatae 10-15 part, Radix Codonopsis 10-15 part, Radix Rehmanniae 5-10 part, Radix Platycodonis
5-10 part, Herba Menthae 5-10 part, Radix Glycyrrhizae 5-10 part.
The Chinese medicine composition with the sore-throat relieving effect that wets one's whistle the most according to claim 1, it is characterised in that it comprises following weight
The raw material of amount number:
Bulbus Fritillariae Thunbergii 15 parts, Fructus Phyllanthi 10 parts, Pericarpium Citri Reticulatae 10 parts, Radix Codonopsis 10 parts, 5 parts of the Radix Rehmanniae, Radix Platycodonis 5 parts, Herba Menthae 5 parts,
5 parts of Radix Glycyrrhizae.
The Chinese medicine composition with the sore-throat relieving effect that wets one's whistle the most according to claim 1, it is characterised in that it comprises following weight
The raw material of amount number:
Bulbus Fritillariae Thunbergii 20 parts, Fructus Phyllanthi 15 parts, Pericarpium Citri Reticulatae 15 parts, Radix Codonopsis 15 parts, 10 parts of the Radix Rehmanniae, Radix Platycodonis 10 parts, Herba Menthae 10
Part, 10 parts of Radix Glycyrrhizae.
4. having described in claim 1 wets one's whistle the preparation method of Chinese medicine composition of sore-throat relieving effect, it is characterised in that include with
Lower step:
(1) take Herba Menthae by weight, use extraction by steam distillation, isolated volatile oil and Herba Menthae medicinal residues；
(2) Fructus Phyllanthi is taken by weight, Pericarpium Citri Reticulatae, Radix Codonopsis, the Radix Rehmanniae, Radix Platycodonis, Radix Glycyrrhizae and step (1) Herba Menthae medicinal residues, add
The soak by water 1 of medical material weight 8～10 times amount volume～3 times, each 1～2 hour, filter and remove residue, united extraction liquid, filtrate concentrated
Obtain extractum；
(3) taking step (2) and extract the extractum that obtains, add Bulbus Fritillariae Thunbergii fine powder, be subsequently adding that step (1) prepares is thin
Lotus volatile oil, is subsequently adding adjuvant, granule processed, is dried.
The preparation method of the Chinese medicine composition with the sore-throat relieving effect that wets one's whistle the most according to claim 4, it is characterised in that bag
Include following steps:
(1) take Herba Menthae by weight, use extraction by steam distillation, isolated volatile oil and Herba Menthae medicinal residues；
(2) Fructus Phyllanthi is taken by weight, Pericarpium Citri Reticulatae, Radix Codonopsis, the Radix Rehmanniae, Radix Platycodonis, Radix Glycyrrhizae and step (1) Herba Menthae medicinal residues, add
The soak by water of medical material weight 10 times amount volume 2 times, each 1 hour, filter and remove residue, united extraction liquid, filtrate was concentrated to give extractum；
(3) taking step (2) and extract the extractum that obtains, add Bulbus Fritillariae Thunbergii fine powder, be subsequently adding that step (1) prepares is thin
Lotus volatile oil, is subsequently adding adjuvant, granule processed, is dried.
6. the wet one's whistle Chinese medicine composition of sore-throat relieving effect of having described in any one of claims 1 to 3 prevents and treats pharyngolaryngitis disease in preparation
Medicine or health product in application.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610274517.9A CN105920295A (en) | 2016-04-28 | 2016-04-28 | Traditional Chinese medicine composition with effects of moistening throat and relieving sore throat and its preparation method and use |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610274517.9A CN105920295A (en) | 2016-04-28 | 2016-04-28 | Traditional Chinese medicine composition with effects of moistening throat and relieving sore throat and its preparation method and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105920295A true CN105920295A (en) | 2016-09-07 |
Family
ID=56836566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610274517.9A Pending CN105920295A (en) | 2016-04-28 | 2016-04-28 | Traditional Chinese medicine composition with effects of moistening throat and relieving sore throat and its preparation method and use |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105920295A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106138360A (en) * | 2016-09-27 | 2016-11-23 | 无限极（中国）有限公司 | A kind of Chinese medicine composition and preparation method thereof, application |
| CN107029159A (en) * | 2017-06-08 | 2017-08-11 | 湖南云从科技有限公司 | It is a kind of to treat oral liquid that throat swells and ache and preparation method thereof |
| CN109511982A (en) * | 2018-12-26 | 2019-03-26 | 江苏朸健生命科技发展有限公司 | Composition and its preparation method and application with throat-clearing lung-moistening effect |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1663604A (en) * | 2003-12-31 | 2005-09-07 | 赵恒� | Spray for treating chronic pharyngitis |
| CN101461888A (en) * | 2009-01-07 | 2009-06-24 | 杨少辉 | Traditional Chinese medicine formula for treating pharyngitis |
| CN103800693A (en) * | 2014-03-07 | 2014-05-21 | 山东理工大学 | Traditional Chinese medicine preparation for treating chronic pharyngitis |
| CN105232939A (en) * | 2015-11-23 | 2016-01-13 | 贵州省仁怀市雨花中药材种植有限公司 | Lozenge treating chronic pharyngitis |
-
2016
- 2016-04-28 CN CN201610274517.9A patent/CN105920295A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1663604A (en) * | 2003-12-31 | 2005-09-07 | 赵恒� | Spray for treating chronic pharyngitis |
| CN101461888A (en) * | 2009-01-07 | 2009-06-24 | 杨少辉 | Traditional Chinese medicine formula for treating pharyngitis |
| CN103800693A (en) * | 2014-03-07 | 2014-05-21 | 山东理工大学 | Traditional Chinese medicine preparation for treating chronic pharyngitis |
| CN105232939A (en) * | 2015-11-23 | 2016-01-13 | 贵州省仁怀市雨花中药材种植有限公司 | Lozenge treating chronic pharyngitis |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106138360A (en) * | 2016-09-27 | 2016-11-23 | 无限极（中国）有限公司 | A kind of Chinese medicine composition and preparation method thereof, application |
| CN107029159A (en) * | 2017-06-08 | 2017-08-11 | 湖南云从科技有限公司 | It is a kind of to treat oral liquid that throat swells and ache and preparation method thereof |
| CN109511982A (en) * | 2018-12-26 | 2019-03-26 | 江苏朸健生命科技发展有限公司 | Composition and its preparation method and application with throat-clearing lung-moistening effect |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104041650B (en) | Heat-removing throat-smoothing lozenges containing traditional Chinese medicine plant extracts and preparation method thereof | |
| CN102293303A (en) | Fire-clearing health-care tea | |
| CN103169891B (en) | Novel vitamin C yinqiao tablet | |
| WO2022134245A1 (en) | Heat-clearing and exterior syndrome-relieving traditional chinese medicine composition and preparation method therefor | |
| CN104189588A (en) | Vitamin C Yinqiao tablets and preparation method thereof | |
| CN102973776A (en) | Chicken respiratory disease prevention and treatment traditional Chinese medicine composition and preparation method thereof | |
| CN102319367A (en) | Medicine used for treating chronic pharyngolaryngitis and vocal cord diseases | |
| CN105920295A (en) | Traditional Chinese medicine composition with effects of moistening throat and relieving sore throat and its preparation method and use | |
| CN105641419A (en) | Traditional Chinese medicine composition for treating Yin deficiency type cough caused by lung cancer | |
| CN102949526A (en) | Healthcare particles for treating chronic pharyngitis and preparation method thereof | |
| CN1985923A (en) | Medicine composition for preventing and treating throat diseases and its preparing method | |
| CN103417875A (en) | Traditional Chinese medicine preparation for treating chronic bronchitis and preparing method thereof | |
| CN107362271A (en) | A kind of Chinese medicine composition for treating breathing problem and preparation method thereof | |
| CN104524256A (en) | Traditional Chinese medicine for treating viral pneumonia | |
| CN104800288A (en) | Traditional Chinese medicine for treating acute viral pharyngitis | |
| CN105797092B (en) | Yiyuan anti-cold mixture | |
| CN103110743B (en) | Traditional Chinese medicine composition for treating or preventing neurasthenia and preparation method thereof | |
| CN109674854A (en) | A kind of shield pharynx treasure pill and preparation method thereof | |
| CN102772645B (en) | Traditional Chinese medicine for treating cold and preparation method thereof | |
| CN103585434B (en) | Traditional Chinese medicine composition for treating anemia | |
| CN109157632B (en) | Formula and preparation method of granules for treating epigastric pain | |
| CN105055882A (en) | Traditional Chinese medicine for treating acute epiglottitis | |
| CN107041923A (en) | It is a kind of that there is clearing lung-heat, cough-relieving, composition of resolving sputum function and preparation method thereof | |
| CN105362938A (en) | Traditional Chinese medicine preparation for treating pharyngolaryngitis and preparation method of traditional Chinese medicine preparation for treating pharyngolaryngitis | |
| CN103610884B (en) | A kind of preparation method of composite reineckia carnea oral preparation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160907 |
|
| RJ01 | Rejection of invention patent application after publication |