CN105920219A - Medicine for treating eczema - Google Patents
Medicine for treating eczema Download PDFInfo
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- CN105920219A CN105920219A CN201610246737.0A CN201610246737A CN105920219A CN 105920219 A CN105920219 A CN 105920219A CN 201610246737 A CN201610246737 A CN 201610246737A CN 105920219 A CN105920219 A CN 105920219A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
- A61K36/515—Gentiana
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Abstract
The invention relates to a medicine for treating eczema. The medicine is prepared from the following medicinal materials in parts by weight: 7 parts of rhizoma belamcandae, 4 parts of radix gentianae, 7 parts of puncturevine caltrop fruits, 9 parts of bark of himalayan coralbean, 8 parts of herba eupatorii, 10 parts of fructus kochiae, and 9 parts of meadowrue root and rhizome. According to the medicine, rhizoma belamcandae has the efficacies of clearing away heat and toxic materials, eliminating phlegm and relieving sore throat, as well as removing blood stasis and dispersing stagnation; radix gentianae has the efficacies of clearing away heat and drying dampness, as well as clearing away the liver-fire and arresting convulsion; puncturevine caltrop fruits have the efficacies of calming the liver and dispelling melancholy, and dispelling pathogenic wind for improving eyesight; the bark of himalayan coralbean has the efficacies of dispelling wind and eliminating dampness, relaxing muscles and tendons and removing obstruction from meridians, as well as killing parasites to relieve itching; herba eupatorii has the efficacies of relieving summer-heat and resolving dampness, as well as repelling the foulness and regulating the middle warmer; fructus kochiae has the efficacies of clearing heat and promoting diuresis, as well as dispelling wind and arresting itching; meadowrue root and rhizome have the efficacies of clearing away heat and drying dampness, and purging fire for removing toxins. The medicinal materials are mixed for achieving the efficacies of clearing away heat and toxic materials, clearing damp, nourishing blood to expel wind, as well as clearing away heat and eliminating dampness. The clinical experiment proves that the medicine can safely and effectively treat eczema.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of medicine for treating eczema.
Background technology
Eczema is the allergy of the easily recurrence of a kind of common acute pruritus caused by multiple internal and external factor
Dermatosis, is apt to occur in head, extremity bend the position such as side and perineum, often in general or symmetry distribution.Eczema
It is many because of property disease, it is considered that closely related with allergy.Part and endocrine dysfunction, plant
Nervous dysfunction is relevant；Inherited genetic factors is also one of primary disease factor.The cause of disease is complicated to be brought to primary disease treatment
Certain difficulty.Divide three phases acute, subacute, chronic.Acute stage tool oozes out tendency, chronic phase then infiltrates,
Plump.Some patient directly translates into chronic eczema.Skin lesion has pleomorphism, symmetry, pruritus and the most anti-
The features such as recurrence work.
Ancient Chinese medicine document is without the name of disease of " eczema ", according to its Clinical symptoms, Master Home in " acute eczema ",
The category of " noxious dampness ", according to its site of pathological change is different, title is different again.It is " ecthyma " such as be born in shank,
It is born in the fossa cubitalis or muscular prominence fossa part " atopic eczema ", is born in scrotum lower more than ten kinds such as " eczema of scrotum " title.
The cause of disease
Eczematosis, because of complexity, is often internal and external reasons interaction result.Endogenous cause of ill such as chronic digestive system disease, essence
God anxiety, insomnia, fatigue, emotion changes, endocrine disturbance, infection, dysbolism etc.,
Exopathogenic factor such as living environment, climate change, food etc. all can affect the generation of eczema.Environmental stimuli such as daylight,
Cold, be dried, hot, hot water is scalded and various animal skin, plant, cosmetics, soap, artificial
Fibers etc. all can induce.It it is a kind of delayed allergy that causes of the complicated inside and outside factor.
Clinical manifestation
It is divided into three phases acute, subacute, chronic by skin lesion performance.
1. it is pimple, papulovesicle or the phlysis of most intensive foxtail millet grain size at the beginning of acute eczema skin lesion, substrate
Flushing, gradually merges in flakes, owing to scratching, pimple, papulovesicle or vesicle top scratch after in obvious point
Shape oozes out and little rotten to the corn face, blur margin.Such as secondary infection, inflammation becomes apparent from, can be formed pustule, pus crusts,
Folliculitis, furuncle etc..Conscious violent pruritus.After being apt to occur in head, ear, distal limbs, scrotum, crissum etc.,
Many symmetrical issues.
2., after subacute eczema acute eczema inflammation alleviates, skin lesion is based on little pimple, incrustation and squama, only
See a small amount of papulovesicle and erosion.Still there is violent pruritus.
3. chronic eczema does not often more transfer chronic eczema to because of acute, subacute eczema recurrent exerbation；Also can open
Begin to be chronic eczema.Show as illing skin to thicken, infiltrate, brownish red or pigmentation, rough surface,
Cover squama, or form a scab because scratching.Conscious acute pruritus.Be common in shank, hands, foot, the fossa cubitalis, nest,
Pudendum, anus etc..The course of disease is indefinite, easily recurs, and prolonged does not heals.
The scope involved according to skin lesion, is divided into limitation eczema and the big class of universal eczema two.
1. limitation eczema occurs over just specific part, i.e. can name with position, as wet in hand eczema, cysthus
Rash, eczema scrotum, ear eczema, breast eczema, anal eczema, legs eczema etc..
2. universal eczema skin lesion is many, general or distribute in the multiple position of whole body.As coin eczema, self
Sensitivity eczema, weary lipid eczema.
Drug therapy
1. selecting antihistaminic antipruritic, two kinds coordinate or are used alternatingly if desired.Universal eczema orally available or
Injection glucocorticoid, but unsuitable life-time service.
2. treatment by Chinese herbs is started with marrow, whole body therapeutic, makes disease start to take a turn for the better, and human body recovers normal physiological machine
Energy.
Medical material involved in the present invention all seen from be recorded in " China book on Chinese herbal medicine ".
Summary of the invention
It is desirable to provide a kind of medicine for treating eczema, by selecting suitable medical material and proportioning thereof,
Reach safely and effectively to cure the purpose of eczema.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of medicine for treating eczema, it is characterised in that it is by the raw medicinal material of following weight proportion
Be prepared from: crow fan 7 parts, Radix Gentianae 4 parts, Fructus Tribuli 7 parts, Cortex erythrinae 9 parts, Herba Eupatorii 8 parts,
Certain herbaceous plants with big flowers 10 parts, Radix et Rhizoma Thalictri 9 parts.
Illustrate the method have the benefit that below in conjunction with theories of Chinese materia medica
It has been recognised by the inventors that eczema is inside and outside because having it concurrently.Endogenous cause of ill is main and body constitution, feelings will, the dirty function of internal organs are lost
Adjust relevant；Exopathogenic factor is the most relevant to diseases caused by exogenous pathogenic factor wind, wet, pathogenic heat and improper diet, and its pathogenesis can be summarized as following
Several aspects.Exopathogen attacks table: space between skin and muscles element is empty, the most often paddles and soaks, and damp pathogen being sticky and stagnant in nature gathers in the flesh natural fibre line of meat, shadow
Ringing and defend gas a surname and send out, battalion defends and becomes estranged, hematogenous blockage, defends outward solid, is easily invaded by the heresy of wind heat, wet with wind,
Heat three heresies are fought mutually knot, fill in the flesh natural fibre line of meat, skin of contaminating, and sending out is eczema.Retention of damp-heat in the interior: innate excess of YANG in the body, addicted to
Food processs arm savoury, wine, cigarette, strong tea, pungent product, and taste are cut down, dysfunction of the spleen in transportation and transformation, and retention of water-damp in the body is strongly fragrant
Heat-transformation for a long time, damp-heat gluing each other is stopped up in skin, affects QI-blood circulation, and sends out eczema.The dry domination of wind of blood: to for heat in blood
Body, because seven emotions are excessive, cause heart-fire flourishing, inside disturb the heart-nutriment, secretly consume painstaking effort, blood deficiency domination of wind, be interwoven in flesh
Skin, causes flesh natural fibre line of meat cervical carcinoma with cachexia, and skin ulcer rash stacks.Spleen asthenia and dampness retention: emptiness of spleen and stomach, or because of intemperance of taking food, kill imapirment of the spleen and stomach,
Cause dysfunction of the spleen in transportation, body fluid not cloth, the wet accumulation of water, stagnate in interior, skin of contaminating, and send out eczema.Therefore treatment
Then taking clearing away heat-damp and promoting diuresis, removing toxic substances of dispeling the wind, invigorating the spleen and stomach, dehumidifying is dispeled the wind.
The present invention uses: crow fan heat-clearing and toxic substances removing, dispelling phlegm and relieving sore-throat, repercussive eliminating stagnation；Radix Gentianae heat clearing and damp drying, rushes down
Liver is calmed the frightened；Fructus Tribuli suppressing the hyperactive liver resolving depression, dispelling pathogenic wind for improving eyesight；Cortex erythrinae expelling wind and removing dampness, channels sootheing and network vessel quickening, killing parasites for relieving itching；
Herba Eupatorii expelling summer-heat and damp, ward off dirty and in；DIKUI clearing away heat-damp and promoting diuresis, method wind is antipruritic；Radix et Rhizoma Thalictri heat clearing and damp drying, pathogenic fire purging
Removing toxic substances.All medicines share, and reach heat-clearing and toxic substances removing, assistant with damp eliminating, nourishing blood to expel wind, effect of clearing away heat and eliminating dampness.
Below in conjunction with clinical laboratory data beneficial effects of the present invention is described:
1, physical data
Inventor collects 84 example eczema patients between in May ,-2015 in March, 2012 altogether.It is randomly divided into: treatment
Organize 42 examples, matched group 42 example.Male 26 examples of wherein treatment group, female 16 example, age 18～63 years old, the course of disease
1 month～4 years；Matched group man 19 examples, female 23 example, between age 19～64 years old, the course of disease 3 months～3 years.
The data such as two groups of sexes, age, courses of disease there was no significant difference, and has comparability.
Diagnostic criteria
1. acute onset, skin lesion is made up of erythema, pimple, vesicle.Cluster slabbing, often causes because scratching
Rotten to the corn, ooze out, form a scab and suppuration etc. changes, blur margin, be often symmetric.
2. can cause from acute eczema recurrent exerbation or start i.e. in chronic.
3. after being apt to occur in face, ear, the position such as elbow, nest, shank, pudendum and anus, companion's play is itched.
4. skin lesion relatively limits to, and plump infiltration is notable, and boundary understands, has pigmentation more.
5. the course of disease is chronic, often has acute attack.
1. inclusive criteria meets diagnostic criteria；2. the age 18～70 years old；3. compliance is good；Sign the most voluntarily
Informed Consent Form.
Exclusion standard 1. gestation, women breast-feeding their children；2. suffer from severe cardiac, lung, liver, renal disease patient；
3. spiritedness systemic disease, it is impossible to partner treatment person；4. through the patient of other drug treatment after morbidity.
2, Therapeutic Method
Treatment group is administered orally the capsule that the present invention prepares according to specific embodiment 3, three times a day.One week treatment.
Matched group is administered orally chlorphenamine, each 4mg, three times a day.One week treatment.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
1. recovery from illness: skin lesion recovers normal, does not itches, or has slight gargalesthesia；
The most effective: 30% skin lesion recovers normal, remaining skin lesion has plumpness or few liquid to ooze out, with scratchiness,
But still can stand；
The most invalid: locally skin lesion is less than improvement standard, or without improving, even deteriorate.
3.2 treatment statistical results are shown in Table 1.
1 liang of table group comparitive study
Visible, eczema can safely and effectively be treated by the medicine that the present invention prepares, and cure rate is high.
Detailed description of the invention
In order to be more fully understood that and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Weigh: crow fan 7 grams, Radix Gentianae 4 grams, Fructus Tribuli 7 grams, Cortex erythrinae 9 grams, Herba Eupatorii 8 grams,
Certain herbaceous plants with big flowers 10 grams, Radix et Rhizoma Thalictri 9 grams；Add 8 times amount water, decoct 1.5 hours, filter；Filtering residue adds 6 times amount water,
Decoct 1 hour, filter；Merging filtrate, is concentrated into 120 grams, must meet one day consumption of adult normal
Decoct.
For treating eczema.Oral, the most once.
Embodiment 2
Weigh: crow fan 7 grams, Radix Gentianae 4 grams, Fructus Tribuli 7 grams, Cortex erythrinae 9 grams, Herba Eupatorii 8 grams,
Certain herbaceous plants with big flowers 10 grams, Radix et Rhizoma Thalictri 9 grams；Add 10 times amount water, decoct 2 hours, filter；Filtering residue adds 8 times amount water,
Decoct 1.5 hours, filter；Merging filtrate, concentrates, and is dried, and packaging must meet adult normal one day
The powder of consumption.
For treating eczema.Oral, every bu is taken for twice sooner or later.
Embodiment 3
Weigh: crow fan 7 grams, Radix Gentianae 4 grams, Fructus Tribuli 7 grams, Cortex erythrinae 9 grams, Herba Eupatorii 8 grams,
Certain herbaceous plants with big flowers 10 grams, Radix et Rhizoma Thalictri 9 grams；Add 6 times amount water, decoct 3 times, decoct 1 hour every time, merge decoction liquor,
Concentrate, be dried, load capsule shells, the capsule of one day consumption of adult normal must be met.
For treating eczema.Oral, every bu morning, noon and afternoon take for three times.
Claims (4)
1. the medicine being used for treating eczema, it is characterised in that it is by the crude drug of following weight proportion
Material is prepared from: crow fan 7 parts, Radix Gentianae 4 parts, Fructus Tribuli 7 parts, Cortex erythrinae 9 parts, Herba Eupatorii 8 parts,
DIKUI 10 parts, Radix et Rhizoma Thalictri 9 parts.
A kind of medicine for treating eczema, it is characterised in that its preparation side
Method is: weigh: crow fan 7 parts, Radix Gentianae 4 parts, Fructus Tribuli 7 parts, Cortex erythrinae 9 parts, Herba Eupatorii 8 parts,
DIKUI 10 parts, Radix et Rhizoma Thalictri 9 parts；Add 8 times amount water, decoct 1.5 hours, filter；Filtering residue adds 6 times amount water,
Decoct 1 hour, filter；Merging filtrate, is concentrated into 120 parts, obtains decoct；Above-mentioned part each means weight
Part.
A kind of medicine for treating eczema, it is characterised in that its preparation side
Method is: weigh: crow fan 7 parts, Radix Gentianae 4 parts, Fructus Tribuli 7 parts, Cortex erythrinae 9 parts, Herba Eupatorii 8 parts,
DIKUI 10 parts, Radix et Rhizoma Thalictri 9 parts；Add 10 times amount water, decoct 2 hours, filter；Filtering residue adds 8 times amount water,
Decoct 1.5 hours, filter；Merging filtrate, concentrates, and is dried, and packaging obtains powder；Above-mentioned part is all
Refer to weight portion.
A kind of medicine for treating eczema, it is characterised in that its preparation side
Method is: weigh: crow fan 7 parts, Radix Gentianae 4 parts, Fructus Tribuli 7 parts, Cortex erythrinae 9 parts, Herba Eupatorii 8 parts,
DIKUI 10 parts, Radix et Rhizoma Thalictri 9 parts；Add 6 times amount water, decoct 3 times, decoct 1 hour every time, merge and decoct
Liquid, concentrates, and is dried, and loads capsule shells, obtains capsule；Above-mentioned part each means weight portion.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610246737.0A CN105920219A (en) | 2016-04-20 | 2016-04-20 | Medicine for treating eczema |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610246737.0A CN105920219A (en) | 2016-04-20 | 2016-04-20 | Medicine for treating eczema |
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| Publication Number | Publication Date |
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| CN105920219A true CN105920219A (en) | 2016-09-07 |
Family
ID=56838462
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN201610246737.0A Withdrawn CN105920219A (en) | 2016-04-20 | 2016-04-20 | Medicine for treating eczema |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101019952B (en) * | 2006-11-20 | 2011-01-12 | 深圳市北科联药业科技有限公司 | Medicine for treating eczema and preparation process of its ointment |
| CN103565980A (en) * | 2012-08-03 | 2014-02-12 | 天津太平洋制药有限公司 | Medicament for treating eczema |
-
2016
- 2016-04-20 CN CN201610246737.0A patent/CN105920219A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101019952B (en) * | 2006-11-20 | 2011-01-12 | 深圳市北科联药业科技有限公司 | Medicine for treating eczema and preparation process of its ointment |
| CN103565980A (en) * | 2012-08-03 | 2014-02-12 | 天津太平洋制药有限公司 | Medicament for treating eczema |
Non-Patent Citations (3)
| Title |
|---|
| 杨阳，等。: ""湿疹辨治经验之处方方法学辨证"", 《中医杂志》 * |
| 程金丽，等。: ""湿疹的中医药治疗概况"", 《药学实践杂志》 * |
| 赖庆远: ""祛湿汤治疗肛门湿疹32例"", 《江西中医药》 * |
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Application publication date: 20160907 |