CN105920170A - Traditional herba preparation preventing hair loss - Google Patents

Traditional herba preparation preventing hair loss Download PDF

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Publication number
CN105920170A
CN105920170A CN201610362756.XA CN201610362756A CN105920170A CN 105920170 A CN105920170 A CN 105920170A CN 201610362756 A CN201610362756 A CN 201610362756A CN 105920170 A CN105920170 A CN 105920170A
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parts
chinese medicine
extracting solution
medicine preparation
mixed
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廖鲜芳
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/37Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/41Crassulaceae (Stonecrop family)
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    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533Leonurus (motherwort)
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/76Salicaceae (Willow family), e.g. poplar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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    • A61K2236/30Extraction of the material
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    • A61K2236/50Methods involving additional extraction steps
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    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

The invention discloses a traditional herba preparation preventing hair loss. The traditional herba preparation is composed of an essence extracting solution and concentration cream. The essence extracting solution is prepared from, by weight, 10-13 parts of wintercreeper, 10-13 parts of peach kernels, 8-10 parts of black sesame, 20-25 parts of leonurus, 5-7 parts of hairyvein agrimony, 3-7 parts of gray gum, 9-12 parts of white polygonum multiflorum, 3-7 parts of serissa serissoide and 3-7 parts of ginseng. The concentration cream is prepared from, by weight, 1-2 parts of rubus idaeus, 3-5 parts of white willow bark extract, 3-5 parts of randia cochinchinensis, 3-5 parts of ox horns, 8-10 parts of wild jujube root bark, 1-2 parts of radix rubiae, 3-5 parts of lavender, 3-5 parts of roasted polygala tenuifolia and 3-5 parts of mulberries. The traditional herba preparation has the effects that few toxic and side effect is caused, and the treatment period is short.

Description

Prevent the Chinese medicine preparation of alopecia
Technical field
The present invention relates to the field of Chinese medicines.It is more particularly related to a kind of Chinese medicine preparation preventing alopecia.
Background technology
Alopecia refers to the phenomenon of alopecia.The hair normally come off is at the hair of catagen and resting stage, pathologic Alopecia refers to hair exception or excessive coming off.Cause a lot of because have of alopecia, substantially have three kinds, the first spirit or body The factor of body, stress be excessively cause alopecia commonly encountered diseases because of.All energy such as psychentonia, melancholy, fear or serious insomnia Causing nervous dysfunction, blood capillary to be continuously in contraction state, hair follicle can not get the blood supply of abundance, and scalp position In the top of human body, thus hair is the most easy to fall off.If pressure continues, it is more weak to add psychological diathesis, the most easily occurs disconnected Send out addiction, food sends out addiction, trichotillomania etc..Injury of head, the pathological changes of spinal cord, oblongata, midbrain and brain stem, all can cause hair Come off.Nervous and Mental Factors also can severely impact the growth cycle of hair, and long asthenopia, stress are overweight, refreshing Through hypertonicity, irritability or worried mood, stay up late, all may result in natural on-off cycles of hair growth cycle time, depilation phenomenon occurs, lead Cause male pattern alopecia.The medicine of some hormoness, though there being certain effect, but its toxic and side effects is relatively big, and after discontinuing medication, also has multiple The possibility sent out.
Summary of the invention
It is an object of the invention to solve at least the above, and the advantage that at least will be described later is provided.
It is a still further object of the present invention to provide a kind of Chinese drugs agentia preventing alopecia, the hair located that comes off can be promoted simultaneously Regeneration, toxic and side effects is little, and treatment cycle is short.
In order to realize according to object of the present invention and further advantage, it is provided that a kind of Chinese medicine preparation preventing alopecia, Described Chinese medicine preparation is made up of elite extracting solution and condensed cream;
Wherein, described elite extracting solution includes the raw material of following weight portion meter: 10-13 part Caulis Seu Folium Euonymi Fortunei, 10-13 part Semen Persicae, 8-10 Part Semen Sesami Nigrum, 20-25 part Herba Leonuri, 5-7 part Herba Agrimoniae, 3-7 part gray gum, the white Radix Polygoni Multiflori of 9-12 part, 3-7 part June Snow and 3-7 part Radix Ginseng;
Described condensed cream includes the raw material of following weight portion meter: 1-2 part Fructus Rubi, 3-5 part Salix Babylonica L.P.E, 3-5 part mountain Clausena lansium (Lour.) Skeels, 3-5 part Cornu Bovis seu Bubali, 8-10 part Cortex Ziziphi spinosae Radicis, 1-2 part Radix Rubiae, 3-5 part lavandula angustifolia, 3-5 part Cortex et Radix Polygalae (processed) and 3-5 part Fructus Mori.
Preferably, described Caulis Seu Folium Euonymi Fortunei, described Semen Persicae, described Semen Sesami Nigrum, described Herba Leonuri, described Herba Agrimoniae, described carefully 80 mesh sieves pulverized respectively by Ye An, described white Radix Polygoni Multiflori, described Serissa foetida and described Radix Ginseng.
Preferably, the preparation method of described elite extracting solution comprises the following steps:
A1: by the Caulis Seu Folium Euonymi Fortunei of above-mentioned parts by weight, Herba Leonuri, Semen Sesami Nigrum and Semen Persicae mix homogeneously, obtain the first mixed-powder, In described first mixed-powder, add the water of its 4-5 times of quality, slow fire boiling 4-6h, be 11000 dalton with molecular weight Ultrafiltration membrance filter, obtain the first filtrate;
A2: by the Herba Agrimoniae of above-mentioned parts by weight, gray gum, white Radix Polygoni Multiflori, Serissa foetida and Radix Ginseng mix homogeneously, obtain second Mixed-powder, the yellow wine of the quality such as addition in described second mixed-powder, soaks 5-7 days at 35 DEG C, with molecular weight is 11000 daltonian ultrafiltration membrance filters, obtain the second filtrate;
A3: the first filtrate and the second filtrate are mixed, obtains described elite extracting solution.
Preferably, the preparation method of described condensed cream comprises the following steps:
B1: by the Fructus Rubi of above-mentioned weight portion, Salix Babylonica L.P.E, Cortex Clausenae Excavatae, Cornu Bovis seu Bubali, Radix Rubiae, lavandula angustifolia, Cortex et Radix Polygalae (processed) Being dried to water content with Fructus Mori is less than 10%, pulverized 80 mesh sieves, and obtained xeraphium;
B2: by the acetone soln reflux, extract, that described xeraphium volume fraction is 70%, Extracting temperature is set to 65 DEG C -75 DEG C, extraction time is 4 hours, extracts 1-2 time, and united extraction liquid obtains xeraphium extracting solution;
B3: by described xeraphium extracting solution concentrating under reduced pressure, and reclaim acetone solvent, obtain thick paste;
B4: by the Cortex Ziziphi spinosae Radicis extraction by steam distillation Cortex Ziziphi spinosae Radicis volatile oil of above-mentioned weight portion;
B5: described thick paste and the described Cortex Ziziphi spinosae Radicis volatile oil that takes are mixed, obtains described condensed cream.
Preferably, in described B3 concentrating under reduced pressure pressure be-0.075MPa, temperature is 58 DEG C.
Preferably, described elite extracting solution and described condensed cream are mixed for 1:3-5 in mass ratio, obtain the 3rd mixture, To join in described 3rd mixture with water-dispersible sodium alginate, and be stirred continuously to described 3rd mixture surface formation Layer of gel, obtains described Chinese medicine preparation.
Preferably, described Chinese medicine preparation is capsule preparations.
The present invention at least includes following beneficial effect: the Chinese medicine preparation of the hair growth of the present invention is minimum to human body toxic and side effects, Curative effect is high, short treating period, can promote the blood circulation of scalp, promotes the growth of hair, supplements vitality of human body, has peace simultaneously God, the effect of suppression scalp antibacterial, prevent hair from continuing to come off, and repairs hair and dries up bifurcated, also has certain black hair merit Effect.Utilize sodium alginate to form gel on the 3rd mixture and extend drug effect, extend the shelf-life of medicine.
Part is embodied by the further advantage of the present invention, target and feature by description below, and part also will be by the present invention Research and practice and be understood by the person skilled in the art.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, to make those skilled in the art with reference to description word Can implement according to this.
Embodiment 1
A kind of Chinese medicine preparation preventing alopecia, described Chinese medicine preparation is made up of elite extracting solution and condensed cream;
Wherein, described elite extracting solution includes the raw material of following weight portion meter: 10 portions of Caulis Seu Folium Euonymi Fortuneis, 10 parts of Semen Persicaes, 8 parts black Semen Sesami, 20 parts of Herba Leonuris, 5 parts of Herba Agrimoniaes, 3 portions of gray gums, 9 parts of white Radix Polygoni Multiflori, 3 parts of Serissa foetida and 3 parts of Radix Ginsengs; 80 mesh sieves pulverized respectively by above-mentioned Chinese medicine.
The preparation method of described elite extracting solution comprises the following steps:
A1: by the Caulis Seu Folium Euonymi Fortunei of above-mentioned parts by weight, Herba Leonuri, Semen Sesami Nigrum and Semen Persicae mix homogeneously, obtain the first mixed-powder, Adding the water of its 4 times of quality in described first mixed-powder, slow fire boiling 4h, is 11000 daltonian super with molecular weight Membrane filtration, obtains the first filtrate;
A2: by the Herba Agrimoniae of above-mentioned parts by weight, gray gum, white Radix Polygoni Multiflori, Serissa foetida and Radix Ginseng mix homogeneously, obtain second Mixed-powder, the yellow wine of the quality such as addition in described second mixed-powder, soaks 5 days at 35 DEG C, with molecular weight is 11000 daltonian ultrafiltration membrance filters, obtain the second filtrate;
A3: the first filtrate and the second filtrate are mixed, obtains described elite extracting solution.
Described condensed cream includes the raw material of following weight portion meter: 1 portion of Fructus Rubi, 3 parts of Salix Babylonica L.P.Es, 3 parts of Cortex Clausenae Excavataes, 3 parts of Cornu Boviss seu Bubali, 8 parts of Cortex Ziziphi spinosae Radiciss, 1 portion of Radix Rubiae, 3 parts of lavandula angustifoliaes, 3 parts of Cortex et Radix Polygalae (processed) and 3 parts of Fructus Mori.
The preparation method of described condensed cream comprises the following steps:
B1: by the Fructus Rubi of above-mentioned weight portion, Salix Babylonica L.P.E, Cortex Clausenae Excavatae, Cornu Bovis seu Bubali, Radix Rubiae, lavandula angustifolia, Cortex et Radix Polygalae (processed) Being dried to water content with Fructus Mori is less than 10%, pulverized 80 mesh sieves, and obtained xeraphium;
B2: by the acetone soln reflux, extract, that described xeraphium volume fraction is 70%, Extracting temperature is set to 65 DEG C, Extraction time is 4 hours, extracts 1 time, united extraction liquid, obtains xeraphium extracting solution;
B3: by described xeraphium extracting solution concentrating under reduced pressure, pressure is-0.075MPa, and temperature is 58 DEG C, and it is molten to reclaim acetone Agent, obtains thick paste;
B4: by the Cortex Ziziphi spinosae Radicis extraction by steam distillation Cortex Ziziphi spinosae Radicis volatile oil of above-mentioned weight portion;
B5: described thick paste and the described Cortex Ziziphi spinosae Radicis volatile oil that takes are mixed, obtains described condensed cream.
Described elite extracting solution and described condensed cream are mixed for 1:3 in mass ratio, obtains the 3rd mixture, by with water-dispersible Sodium alginate joins in described 3rd mixture, and is stirred continuously to described 3rd mixture surface formation layer of gel, i.e. Obtain described Chinese medicine preparation, described Chinese medicine preparation is made as capsule preparations.
Embodiment 2
A kind of Chinese medicine preparation preventing alopecia, described Chinese medicine preparation is made up of elite extracting solution and condensed cream;
Wherein, described elite extracting solution includes the raw material of following weight portion meter: 13 portions of Caulis Seu Folium Euonymi Fortuneis, 13 parts of Semen Persicaes, 10 parts black Semen Sesami, 25 parts of Herba Leonuris, 7 parts of Herba Agrimoniaes, 7 portions of gray gums, 12 parts of white Radix Polygoni Multiflori, 7 parts of Serissa foetida and 7 parts of Radix Ginsengs; 80 mesh sieves pulverized respectively by above-mentioned Chinese medicine.
The preparation method of described elite extracting solution comprises the following steps:
A1: by the Caulis Seu Folium Euonymi Fortunei of above-mentioned parts by weight, Herba Leonuri, Semen Sesami Nigrum and Semen Persicae mix homogeneously, obtain the first mixed-powder, Adding the water of its 5 times of quality in described first mixed-powder, slow fire boiling 6h, is 11000 daltonian super with molecular weight Membrane filtration, obtains the first filtrate;
A2: by the Herba Agrimoniae of above-mentioned parts by weight, gray gum, white Radix Polygoni Multiflori, Serissa foetida and Radix Ginseng mix homogeneously, obtain second Mixed-powder, the yellow wine of the quality such as addition in described second mixed-powder, soaks 7 days at 35 DEG C, with molecular weight is 11000 daltonian ultrafiltration membrance filters, obtain the second filtrate;
A3: the first filtrate and the second filtrate are mixed, obtains described elite extracting solution.
Described condensed cream includes the raw material of following weight portion meter: 2 portions of Fructus Rubies, 5 parts of Salix Babylonica L.P.Es, 5 parts of Cortex Clausenae Excavataes, 5 parts of Cornu Boviss seu Bubali, 10 parts of Cortex Ziziphi spinosae Radiciss, 2 portions of Radix Rubiaes, 5 parts of lavandula angustifoliaes, 5 parts of Cortex et Radix Polygalae (processed) and 5 parts of Fructus Mori.
The preparation method of described condensed cream comprises the following steps:
B1: by the Fructus Rubi of above-mentioned weight portion, Salix Babylonica L.P.E, Cortex Clausenae Excavatae, Cornu Bovis seu Bubali, Radix Rubiae, lavandula angustifolia, Cortex et Radix Polygalae (processed) Being dried to water content with Fructus Mori is less than 10%, pulverized 80 mesh sieves, and obtained xeraphium;
B2: by the acetone soln reflux, extract, that described xeraphium volume fraction is 70%, Extracting temperature is set to 75 DEG C, Extraction time is 4 hours, extracts 2 times, united extraction liquid, obtains xeraphium extracting solution;
B3: by described xeraphium extracting solution concentrating under reduced pressure, pressure is-0.075MPa, and temperature is 58 DEG C, and it is molten to reclaim acetone Agent, obtains thick paste;
B4: by the Cortex Ziziphi spinosae Radicis extraction by steam distillation Cortex Ziziphi spinosae Radicis volatile oil of above-mentioned weight portion;
B5: described thick paste and the described Cortex Ziziphi spinosae Radicis volatile oil that takes are mixed, obtains described condensed cream.
Described elite extracting solution and described condensed cream are mixed for 1:5 in mass ratio, obtains the 3rd mixture, by with water-dispersible Sodium alginate joins in described 3rd mixture, and is stirred continuously to described 3rd mixture surface formation layer of gel, i.e. Obtain described Chinese medicine preparation, described Chinese medicine preparation is made as capsule preparations.
Embodiment 3
A kind of Chinese medicine preparation preventing alopecia, described Chinese medicine preparation is made up of elite extracting solution and condensed cream;
Wherein, described elite extracting solution includes the raw material of following weight portion meter: 11 parts of Caulis Seu Folium Euonymi Fortuneis, 11 parts of Semen Persicaes, 9 parts of Fructificatio Amaurodermatis Rudae Fiber crops, 22 parts of Herba Leonuris, 6 parts of Herba Agrimoniaes, 5 portions of gray gums, 10 parts of white Radix Polygoni Multiflori, 5 parts of Serissa foetida and 5 parts of Radix Ginsengs;On State Chinese medicine and pulverize 80 mesh sieves respectively.
The preparation method of described elite extracting solution comprises the following steps:
A1: by the Caulis Seu Folium Euonymi Fortunei of above-mentioned parts by weight, Herba Leonuri, Semen Sesami Nigrum and Semen Persicae mix homogeneously, obtain the first mixed-powder, Adding the water of its 4 times of quality in described first mixed-powder, slow fire boiling 5h, is 11000 daltonian super with molecular weight Membrane filtration, obtains the first filtrate;
A2: by the Herba Agrimoniae of above-mentioned parts by weight, gray gum, white Radix Polygoni Multiflori, Serissa foetida and Radix Ginseng mix homogeneously, obtain second Mixed-powder, the yellow wine of the quality such as addition in described second mixed-powder, soaks 6 days at 35 DEG C, with molecular weight is 11000 daltonian ultrafiltration membrance filters, obtain the second filtrate;
A3: the first filtrate and the second filtrate are mixed, obtains described elite extracting solution.
Described condensed cream includes the raw material of following weight portion meter: 1 portion of Fructus Rubi, 4 parts of Salix Babylonica L.P.Es, 4 parts of Cortex Clausenae Excavataes, 4 parts of Cornu Boviss seu Bubali, 9 parts of Cortex Ziziphi spinosae Radiciss, 1 portion of Radix Rubiae, 4 parts of lavandula angustifoliaes, 4 parts of Cortex et Radix Polygalae (processed) and 4 parts of Fructus Mori.
The preparation method of described condensed cream comprises the following steps:
B1: by the Fructus Rubi of above-mentioned weight portion, Salix Babylonica L.P.E, Cortex Clausenae Excavatae, Cornu Bovis seu Bubali, Radix Rubiae, lavandula angustifolia, Cortex et Radix Polygalae (processed) Being dried to water content with Fructus Mori is less than 10%, pulverized 80 mesh sieves, and obtained xeraphium;
B2: by the acetone soln reflux, extract, that described xeraphium volume fraction is 70%, Extracting temperature is set to 70 DEG C, Extraction time is 4 hours, extracts 1 time, united extraction liquid, obtains xeraphium extracting solution;
B3: by described xeraphium extracting solution concentrating under reduced pressure, pressure is-0.075MPa, and temperature is 58 DEG C, and it is molten to reclaim acetone Agent, obtains thick paste;
B4: by the Cortex Ziziphi spinosae Radicis extraction by steam distillation Cortex Ziziphi spinosae Radicis volatile oil of above-mentioned weight portion;
B5: described thick paste and the described Cortex Ziziphi spinosae Radicis volatile oil that takes are mixed, obtains described condensed cream.
Described elite extracting solution and described condensed cream are mixed for 1:4 in mass ratio, obtains the 3rd mixture, by with water-dispersible Sodium alginate joins in described 3rd mixture, and is stirred continuously to described 3rd mixture surface formation layer of gel, i.e. Obtain described Chinese medicine preparation, described Chinese medicine preparation is made as capsule preparations.
Clinical trial:
300 example hair loss patients local to the North Sea carry out clinical observation treatment, and wherein male's case is 220 examples, and women case is 80 examples, the mean age is 30-70 year, 55 years old mean age.
Therapeutic Method:
The capsule that oral embodiment 3 prepares, twice on the one, each one, one after each meal, according to the weight meter of conditions of patients Calculating treatment time, patients with mild is taken 20-30 days, and severe case takes 31-60 days.
Outcome measure:
Curing, it is more than 95% that former alopecia director makes new advances that fermentation amasss.
Effectively, former alopecia director makes new advances that fermentation amasss is more than 40%.
Invalid, it is less than 40% that former alopecia director makes new advances that fermentation amasss.
Therapeutic outcome:
Clinical cure 258 example (86%), effective 36 examples (12%), invalid 6 examples (2%), total effective rate is 98%.
Although embodiment of the present invention are disclosed as above, but it is not restricted in description and embodiment listed fortune With, it can be applied to various applicable the field of the invention completely, for those skilled in the art, and can be easily Realizing other amendment, therefore under the general concept limited without departing substantially from claim and equivalency range, the present invention does not limit In specific details with shown here as the embodiment with description.

Claims (7)

1. the Chinese medicine preparation preventing alopecia, it is characterised in that described Chinese medicine preparation is by elite extracting solution and concentration Cream forms;
Wherein, described elite extracting solution includes the raw material of following weight portion meter: 10-13 part Caulis Seu Folium Euonymi Fortunei, 10-13 part Semen Persicae, 8-10 Part Semen Sesami Nigrum, 20-25 part Herba Leonuri, 5-7 part Herba Agrimoniae, 3-7 part gray gum, the white Radix Polygoni Multiflori of 9-12 part, 3-7 part June Snow and 3-7 part Radix Ginseng;
Described condensed cream includes the raw material of following weight portion meter: 1-2 part Fructus Rubi, 3-5 part Salix Babylonica L.P.E, 3-5 part mountain Clausena lansium (Lour.) Skeels, 3-5 part Cornu Bovis seu Bubali, 8-10 part Cortex Ziziphi spinosae Radicis, 1-2 part Radix Rubiae, 3-5 part lavandula angustifolia, 3-5 part Cortex et Radix Polygalae (processed) and 3-5 part Fructus Mori.
Prevent the Chinese medicine preparation of alopecia the most as claimed in claim 1, it is characterised in that described Caulis Seu Folium Euonymi Fortunei, described Semen Persicae, described Semen Sesami Nigrum, described Herba Leonuri, described Herba Agrimoniae, described gray gum, described white Radix Polygoni Multiflori, described Serissa foetida 80 mesh sieves were pulverized respectively with described Radix Ginseng.
Prevent the Chinese medicine preparation of alopecia the most as claimed in claim 2, it is characterised in that described elite extracting solution Preparation method comprises the following steps:
A1: by the Caulis Seu Folium Euonymi Fortunei of above-mentioned parts by weight, Herba Leonuri, Semen Sesami Nigrum and Semen Persicae mix homogeneously, obtain the first mixed-powder, In described first mixed-powder, add the water of its 4-5 times of quality, slow fire boiling 4-6h, be 11000 dalton with molecular weight Ultrafiltration membrance filter, obtain the first filtrate;
A2: by the Herba Agrimoniae of above-mentioned parts by weight, gray gum, white Radix Polygoni Multiflori, Serissa foetida and Radix Ginseng mix homogeneously, obtain second Mixed-powder, the yellow wine of the quality such as addition in described second mixed-powder, soaks 5-7 days at 35 DEG C, with molecular weight is 11000 daltonian ultrafiltration membrance filters, obtain the second filtrate;
A3: the first filtrate and the second filtrate are mixed, obtains described elite extracting solution.
Prevent the Chinese medicine preparation of alopecia the most as claimed in claim 2, it is characterised in that the preparation of described condensed cream Method comprises the following steps:
B1: by the Fructus Rubi of above-mentioned weight portion, Salix Babylonica L.P.E, Cortex Clausenae Excavatae, Cornu Bovis seu Bubali, Radix Rubiae, lavandula angustifolia, Cortex et Radix Polygalae (processed) Being dried to water content with Fructus Mori is less than 10%, pulverized 80 mesh sieves, and obtained xeraphium;
B2: by the acetone soln reflux, extract, that described xeraphium volume fraction is 70%, Extracting temperature is set to 65 DEG C -75 DEG C, extraction time is 4 hours, extracts 1-2 time, and united extraction liquid obtains xeraphium extracting solution;
B3: by described xeraphium extracting solution concentrating under reduced pressure, and reclaim acetone solvent, obtain thick paste;
B4: by the Cortex Ziziphi spinosae Radicis extraction by steam distillation Cortex Ziziphi spinosae Radicis volatile oil of above-mentioned weight portion;
B5: described thick paste and the described Cortex Ziziphi spinosae Radicis volatile oil that takes are mixed, obtains described condensed cream.
Prevent the Chinese medicine preparation of alopecia the most as claimed in claim 4, it is characterised in that described B3 reduces pressure dense Contracting pressure be-0.075MPa, temperature is 58 DEG C.
Prevent the Chinese medicine preparation of alopecia the most as claimed in claim 2, it is characterised in that described elite extracted Liquid and described condensed cream mix for 1:3-5 in mass ratio, obtain the 3rd mixture, will join with water-dispersible sodium alginate In described 3rd mixture, and it is stirred continuously to described 3rd mixture surface formation layer of gel, obtains described Chinese medicine system Agent.
Prevent the Chinese medicine preparation of alopecia the most as claimed in claim 6, it is characterised in that described Chinese medicine preparation is Capsule preparations.
CN201610362756.XA 2016-05-27 2016-05-27 Traditional herba preparation preventing hair loss Pending CN105920170A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113057927A (en) * 2021-03-29 2021-07-02 中科瑞晟芳香产业研究院(湖北)有限公司 Hair-strengthening shampoo containing aromatic Chinese herbal medicines

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1087267A (en) * 1992-11-23 1994-06-01 梅晓春 A kind of prescription for the treatment of seborrheic alopecia
CN101293040A (en) * 2008-06-06 2008-10-29 思雪花 Chinese medicine for generating and nourishing hair
CN104689285A (en) * 2015-03-31 2015-06-10 刘凤伟 Traditional Chinese preparation for treating alopecia
CN104984141A (en) * 2015-07-29 2015-10-21 张光泉 Prescription for treating constipation and preparation method thereof
CN105596940A (en) * 2015-12-26 2016-05-25 薛学明 Drug for treating alopecia and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1087267A (en) * 1992-11-23 1994-06-01 梅晓春 A kind of prescription for the treatment of seborrheic alopecia
CN101293040A (en) * 2008-06-06 2008-10-29 思雪花 Chinese medicine for generating and nourishing hair
CN104689285A (en) * 2015-03-31 2015-06-10 刘凤伟 Traditional Chinese preparation for treating alopecia
CN104984141A (en) * 2015-07-29 2015-10-21 张光泉 Prescription for treating constipation and preparation method thereof
CN105596940A (en) * 2015-12-26 2016-05-25 薛学明 Drug for treating alopecia and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113057927A (en) * 2021-03-29 2021-07-02 中科瑞晟芳香产业研究院(湖北)有限公司 Hair-strengthening shampoo containing aromatic Chinese herbal medicines

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Application publication date: 20160907