CN105920170A - Traditional herba preparation preventing hair loss - Google Patents
Traditional herba preparation preventing hair loss Download PDFInfo
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- CN105920170A CN105920170A CN201610362756.XA CN201610362756A CN105920170A CN 105920170 A CN105920170 A CN 105920170A CN 201610362756 A CN201610362756 A CN 201610362756A CN 105920170 A CN105920170 A CN 105920170A
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/37—Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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Abstract
The invention discloses a traditional herba preparation preventing hair loss. The traditional herba preparation is composed of an essence extracting solution and concentration cream. The essence extracting solution is prepared from, by weight, 10-13 parts of wintercreeper, 10-13 parts of peach kernels, 8-10 parts of black sesame, 20-25 parts of leonurus, 5-7 parts of hairyvein agrimony, 3-7 parts of gray gum, 9-12 parts of white polygonum multiflorum, 3-7 parts of serissa serissoide and 3-7 parts of ginseng. The concentration cream is prepared from, by weight, 1-2 parts of rubus idaeus, 3-5 parts of white willow bark extract, 3-5 parts of randia cochinchinensis, 3-5 parts of ox horns, 8-10 parts of wild jujube root bark, 1-2 parts of radix rubiae, 3-5 parts of lavender, 3-5 parts of roasted polygala tenuifolia and 3-5 parts of mulberries. The traditional herba preparation has the effects that few toxic and side effect is caused, and the treatment period is short.
Description
Technical field
The present invention relates to the field of Chinese medicines.It is more particularly related to a kind of Chinese medicine preparation preventing alopecia.
Background technology
Alopecia refers to the phenomenon of alopecia.The hair normally come off is at the hair of catagen and resting stage, pathologic
Alopecia refers to hair exception or excessive coming off.Cause a lot of because have of alopecia, substantially have three kinds, the first spirit or body
The factor of body, stress be excessively cause alopecia commonly encountered diseases because of.All energy such as psychentonia, melancholy, fear or serious insomnia
Causing nervous dysfunction, blood capillary to be continuously in contraction state, hair follicle can not get the blood supply of abundance, and scalp position
In the top of human body, thus hair is the most easy to fall off.If pressure continues, it is more weak to add psychological diathesis, the most easily occurs disconnected
Send out addiction, food sends out addiction, trichotillomania etc..Injury of head, the pathological changes of spinal cord, oblongata, midbrain and brain stem, all can cause hair
Come off.Nervous and Mental Factors also can severely impact the growth cycle of hair, and long asthenopia, stress are overweight, refreshing
Through hypertonicity, irritability or worried mood, stay up late, all may result in natural on-off cycles of hair growth cycle time, depilation phenomenon occurs, lead
Cause male pattern alopecia.The medicine of some hormoness, though there being certain effect, but its toxic and side effects is relatively big, and after discontinuing medication, also has multiple
The possibility sent out.
Summary of the invention
It is an object of the invention to solve at least the above, and the advantage that at least will be described later is provided.
It is a still further object of the present invention to provide a kind of Chinese drugs agentia preventing alopecia, the hair located that comes off can be promoted simultaneously
Regeneration, toxic and side effects is little, and treatment cycle is short.
In order to realize according to object of the present invention and further advantage, it is provided that a kind of Chinese medicine preparation preventing alopecia,
Described Chinese medicine preparation is made up of elite extracting solution and condensed cream;
Wherein, described elite extracting solution includes the raw material of following weight portion meter: 10-13 part Caulis Seu Folium Euonymi Fortunei, 10-13 part Semen Persicae, 8-10
Part Semen Sesami Nigrum, 20-25 part Herba Leonuri, 5-7 part Herba Agrimoniae, 3-7 part gray gum, the white Radix Polygoni Multiflori of 9-12 part, 3-7 part June
Snow and 3-7 part Radix Ginseng;
Described condensed cream includes the raw material of following weight portion meter: 1-2 part Fructus Rubi, 3-5 part Salix Babylonica L.P.E, 3-5 part mountain
Clausena lansium (Lour.) Skeels, 3-5 part Cornu Bovis seu Bubali, 8-10 part Cortex Ziziphi spinosae Radicis, 1-2 part Radix Rubiae, 3-5 part lavandula angustifolia, 3-5 part Cortex et Radix Polygalae (processed) and 3-5 part
Fructus Mori.
Preferably, described Caulis Seu Folium Euonymi Fortunei, described Semen Persicae, described Semen Sesami Nigrum, described Herba Leonuri, described Herba Agrimoniae, described carefully
80 mesh sieves pulverized respectively by Ye An, described white Radix Polygoni Multiflori, described Serissa foetida and described Radix Ginseng.
Preferably, the preparation method of described elite extracting solution comprises the following steps:
A1: by the Caulis Seu Folium Euonymi Fortunei of above-mentioned parts by weight, Herba Leonuri, Semen Sesami Nigrum and Semen Persicae mix homogeneously, obtain the first mixed-powder,
In described first mixed-powder, add the water of its 4-5 times of quality, slow fire boiling 4-6h, be 11000 dalton with molecular weight
Ultrafiltration membrance filter, obtain the first filtrate;
A2: by the Herba Agrimoniae of above-mentioned parts by weight, gray gum, white Radix Polygoni Multiflori, Serissa foetida and Radix Ginseng mix homogeneously, obtain second
Mixed-powder, the yellow wine of the quality such as addition in described second mixed-powder, soaks 5-7 days at 35 DEG C, with molecular weight is
11000 daltonian ultrafiltration membrance filters, obtain the second filtrate;
A3: the first filtrate and the second filtrate are mixed, obtains described elite extracting solution.
Preferably, the preparation method of described condensed cream comprises the following steps:
B1: by the Fructus Rubi of above-mentioned weight portion, Salix Babylonica L.P.E, Cortex Clausenae Excavatae, Cornu Bovis seu Bubali, Radix Rubiae, lavandula angustifolia, Cortex et Radix Polygalae (processed)
Being dried to water content with Fructus Mori is less than 10%, pulverized 80 mesh sieves, and obtained xeraphium;
B2: by the acetone soln reflux, extract, that described xeraphium volume fraction is 70%, Extracting temperature is set to 65 DEG C
-75 DEG C, extraction time is 4 hours, extracts 1-2 time, and united extraction liquid obtains xeraphium extracting solution;
B3: by described xeraphium extracting solution concentrating under reduced pressure, and reclaim acetone solvent, obtain thick paste;
B4: by the Cortex Ziziphi spinosae Radicis extraction by steam distillation Cortex Ziziphi spinosae Radicis volatile oil of above-mentioned weight portion;
B5: described thick paste and the described Cortex Ziziphi spinosae Radicis volatile oil that takes are mixed, obtains described condensed cream.
Preferably, in described B3 concentrating under reduced pressure pressure be-0.075MPa, temperature is 58 DEG C.
Preferably, described elite extracting solution and described condensed cream are mixed for 1:3-5 in mass ratio, obtain the 3rd mixture,
To join in described 3rd mixture with water-dispersible sodium alginate, and be stirred continuously to described 3rd mixture surface formation
Layer of gel, obtains described Chinese medicine preparation.
Preferably, described Chinese medicine preparation is capsule preparations.
The present invention at least includes following beneficial effect: the Chinese medicine preparation of the hair growth of the present invention is minimum to human body toxic and side effects,
Curative effect is high, short treating period, can promote the blood circulation of scalp, promotes the growth of hair, supplements vitality of human body, has peace simultaneously
God, the effect of suppression scalp antibacterial, prevent hair from continuing to come off, and repairs hair and dries up bifurcated, also has certain black hair merit
Effect.Utilize sodium alginate to form gel on the 3rd mixture and extend drug effect, extend the shelf-life of medicine.
Part is embodied by the further advantage of the present invention, target and feature by description below, and part also will be by the present invention
Research and practice and be understood by the person skilled in the art.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, to make those skilled in the art with reference to description word
Can implement according to this.
Embodiment 1
A kind of Chinese medicine preparation preventing alopecia, described Chinese medicine preparation is made up of elite extracting solution and condensed cream;
Wherein, described elite extracting solution includes the raw material of following weight portion meter: 10 portions of Caulis Seu Folium Euonymi Fortuneis, 10 parts of Semen Persicaes, 8 parts black
Semen Sesami, 20 parts of Herba Leonuris, 5 parts of Herba Agrimoniaes, 3 portions of gray gums, 9 parts of white Radix Polygoni Multiflori, 3 parts of Serissa foetida and 3 parts of Radix Ginsengs;
80 mesh sieves pulverized respectively by above-mentioned Chinese medicine.
The preparation method of described elite extracting solution comprises the following steps:
A1: by the Caulis Seu Folium Euonymi Fortunei of above-mentioned parts by weight, Herba Leonuri, Semen Sesami Nigrum and Semen Persicae mix homogeneously, obtain the first mixed-powder,
Adding the water of its 4 times of quality in described first mixed-powder, slow fire boiling 4h, is 11000 daltonian super with molecular weight
Membrane filtration, obtains the first filtrate;
A2: by the Herba Agrimoniae of above-mentioned parts by weight, gray gum, white Radix Polygoni Multiflori, Serissa foetida and Radix Ginseng mix homogeneously, obtain second
Mixed-powder, the yellow wine of the quality such as addition in described second mixed-powder, soaks 5 days at 35 DEG C, with molecular weight is
11000 daltonian ultrafiltration membrance filters, obtain the second filtrate;
A3: the first filtrate and the second filtrate are mixed, obtains described elite extracting solution.
Described condensed cream includes the raw material of following weight portion meter: 1 portion of Fructus Rubi, 3 parts of Salix Babylonica L.P.Es, 3 parts of Cortex Clausenae Excavataes,
3 parts of Cornu Boviss seu Bubali, 8 parts of Cortex Ziziphi spinosae Radiciss, 1 portion of Radix Rubiae, 3 parts of lavandula angustifoliaes, 3 parts of Cortex et Radix Polygalae (processed) and 3 parts of Fructus Mori.
The preparation method of described condensed cream comprises the following steps:
B1: by the Fructus Rubi of above-mentioned weight portion, Salix Babylonica L.P.E, Cortex Clausenae Excavatae, Cornu Bovis seu Bubali, Radix Rubiae, lavandula angustifolia, Cortex et Radix Polygalae (processed)
Being dried to water content with Fructus Mori is less than 10%, pulverized 80 mesh sieves, and obtained xeraphium;
B2: by the acetone soln reflux, extract, that described xeraphium volume fraction is 70%, Extracting temperature is set to 65 DEG C,
Extraction time is 4 hours, extracts 1 time, united extraction liquid, obtains xeraphium extracting solution;
B3: by described xeraphium extracting solution concentrating under reduced pressure, pressure is-0.075MPa, and temperature is 58 DEG C, and it is molten to reclaim acetone
Agent, obtains thick paste;
B4: by the Cortex Ziziphi spinosae Radicis extraction by steam distillation Cortex Ziziphi spinosae Radicis volatile oil of above-mentioned weight portion;
B5: described thick paste and the described Cortex Ziziphi spinosae Radicis volatile oil that takes are mixed, obtains described condensed cream.
Described elite extracting solution and described condensed cream are mixed for 1:3 in mass ratio, obtains the 3rd mixture, by with water-dispersible
Sodium alginate joins in described 3rd mixture, and is stirred continuously to described 3rd mixture surface formation layer of gel, i.e.
Obtain described Chinese medicine preparation, described Chinese medicine preparation is made as capsule preparations.
Embodiment 2
A kind of Chinese medicine preparation preventing alopecia, described Chinese medicine preparation is made up of elite extracting solution and condensed cream;
Wherein, described elite extracting solution includes the raw material of following weight portion meter: 13 portions of Caulis Seu Folium Euonymi Fortuneis, 13 parts of Semen Persicaes, 10 parts black
Semen Sesami, 25 parts of Herba Leonuris, 7 parts of Herba Agrimoniaes, 7 portions of gray gums, 12 parts of white Radix Polygoni Multiflori, 7 parts of Serissa foetida and 7 parts of Radix Ginsengs;
80 mesh sieves pulverized respectively by above-mentioned Chinese medicine.
The preparation method of described elite extracting solution comprises the following steps:
A1: by the Caulis Seu Folium Euonymi Fortunei of above-mentioned parts by weight, Herba Leonuri, Semen Sesami Nigrum and Semen Persicae mix homogeneously, obtain the first mixed-powder,
Adding the water of its 5 times of quality in described first mixed-powder, slow fire boiling 6h, is 11000 daltonian super with molecular weight
Membrane filtration, obtains the first filtrate;
A2: by the Herba Agrimoniae of above-mentioned parts by weight, gray gum, white Radix Polygoni Multiflori, Serissa foetida and Radix Ginseng mix homogeneously, obtain second
Mixed-powder, the yellow wine of the quality such as addition in described second mixed-powder, soaks 7 days at 35 DEG C, with molecular weight is
11000 daltonian ultrafiltration membrance filters, obtain the second filtrate;
A3: the first filtrate and the second filtrate are mixed, obtains described elite extracting solution.
Described condensed cream includes the raw material of following weight portion meter: 2 portions of Fructus Rubies, 5 parts of Salix Babylonica L.P.Es, 5 parts of Cortex Clausenae Excavataes,
5 parts of Cornu Boviss seu Bubali, 10 parts of Cortex Ziziphi spinosae Radiciss, 2 portions of Radix Rubiaes, 5 parts of lavandula angustifoliaes, 5 parts of Cortex et Radix Polygalae (processed) and 5 parts of Fructus Mori.
The preparation method of described condensed cream comprises the following steps:
B1: by the Fructus Rubi of above-mentioned weight portion, Salix Babylonica L.P.E, Cortex Clausenae Excavatae, Cornu Bovis seu Bubali, Radix Rubiae, lavandula angustifolia, Cortex et Radix Polygalae (processed)
Being dried to water content with Fructus Mori is less than 10%, pulverized 80 mesh sieves, and obtained xeraphium;
B2: by the acetone soln reflux, extract, that described xeraphium volume fraction is 70%, Extracting temperature is set to 75 DEG C,
Extraction time is 4 hours, extracts 2 times, united extraction liquid, obtains xeraphium extracting solution;
B3: by described xeraphium extracting solution concentrating under reduced pressure, pressure is-0.075MPa, and temperature is 58 DEG C, and it is molten to reclaim acetone
Agent, obtains thick paste;
B4: by the Cortex Ziziphi spinosae Radicis extraction by steam distillation Cortex Ziziphi spinosae Radicis volatile oil of above-mentioned weight portion;
B5: described thick paste and the described Cortex Ziziphi spinosae Radicis volatile oil that takes are mixed, obtains described condensed cream.
Described elite extracting solution and described condensed cream are mixed for 1:5 in mass ratio, obtains the 3rd mixture, by with water-dispersible
Sodium alginate joins in described 3rd mixture, and is stirred continuously to described 3rd mixture surface formation layer of gel, i.e.
Obtain described Chinese medicine preparation, described Chinese medicine preparation is made as capsule preparations.
Embodiment 3
A kind of Chinese medicine preparation preventing alopecia, described Chinese medicine preparation is made up of elite extracting solution and condensed cream;
Wherein, described elite extracting solution includes the raw material of following weight portion meter: 11 parts of Caulis Seu Folium Euonymi Fortuneis, 11 parts of Semen Persicaes, 9 parts of Fructificatio Amaurodermatis Rudae
Fiber crops, 22 parts of Herba Leonuris, 6 parts of Herba Agrimoniaes, 5 portions of gray gums, 10 parts of white Radix Polygoni Multiflori, 5 parts of Serissa foetida and 5 parts of Radix Ginsengs;On
State Chinese medicine and pulverize 80 mesh sieves respectively.
The preparation method of described elite extracting solution comprises the following steps:
A1: by the Caulis Seu Folium Euonymi Fortunei of above-mentioned parts by weight, Herba Leonuri, Semen Sesami Nigrum and Semen Persicae mix homogeneously, obtain the first mixed-powder,
Adding the water of its 4 times of quality in described first mixed-powder, slow fire boiling 5h, is 11000 daltonian super with molecular weight
Membrane filtration, obtains the first filtrate;
A2: by the Herba Agrimoniae of above-mentioned parts by weight, gray gum, white Radix Polygoni Multiflori, Serissa foetida and Radix Ginseng mix homogeneously, obtain second
Mixed-powder, the yellow wine of the quality such as addition in described second mixed-powder, soaks 6 days at 35 DEG C, with molecular weight is
11000 daltonian ultrafiltration membrance filters, obtain the second filtrate;
A3: the first filtrate and the second filtrate are mixed, obtains described elite extracting solution.
Described condensed cream includes the raw material of following weight portion meter: 1 portion of Fructus Rubi, 4 parts of Salix Babylonica L.P.Es, 4 parts of Cortex Clausenae Excavataes,
4 parts of Cornu Boviss seu Bubali, 9 parts of Cortex Ziziphi spinosae Radiciss, 1 portion of Radix Rubiae, 4 parts of lavandula angustifoliaes, 4 parts of Cortex et Radix Polygalae (processed) and 4 parts of Fructus Mori.
The preparation method of described condensed cream comprises the following steps:
B1: by the Fructus Rubi of above-mentioned weight portion, Salix Babylonica L.P.E, Cortex Clausenae Excavatae, Cornu Bovis seu Bubali, Radix Rubiae, lavandula angustifolia, Cortex et Radix Polygalae (processed)
Being dried to water content with Fructus Mori is less than 10%, pulverized 80 mesh sieves, and obtained xeraphium;
B2: by the acetone soln reflux, extract, that described xeraphium volume fraction is 70%, Extracting temperature is set to 70 DEG C,
Extraction time is 4 hours, extracts 1 time, united extraction liquid, obtains xeraphium extracting solution;
B3: by described xeraphium extracting solution concentrating under reduced pressure, pressure is-0.075MPa, and temperature is 58 DEG C, and it is molten to reclaim acetone
Agent, obtains thick paste;
B4: by the Cortex Ziziphi spinosae Radicis extraction by steam distillation Cortex Ziziphi spinosae Radicis volatile oil of above-mentioned weight portion;
B5: described thick paste and the described Cortex Ziziphi spinosae Radicis volatile oil that takes are mixed, obtains described condensed cream.
Described elite extracting solution and described condensed cream are mixed for 1:4 in mass ratio, obtains the 3rd mixture, by with water-dispersible
Sodium alginate joins in described 3rd mixture, and is stirred continuously to described 3rd mixture surface formation layer of gel, i.e.
Obtain described Chinese medicine preparation, described Chinese medicine preparation is made as capsule preparations.
Clinical trial:
300 example hair loss patients local to the North Sea carry out clinical observation treatment, and wherein male's case is 220 examples, and women case is
80 examples, the mean age is 30-70 year, 55 years old mean age.
Therapeutic Method:
The capsule that oral embodiment 3 prepares, twice on the one, each one, one after each meal, according to the weight meter of conditions of patients
Calculating treatment time, patients with mild is taken 20-30 days, and severe case takes 31-60 days.
Outcome measure:
Curing, it is more than 95% that former alopecia director makes new advances that fermentation amasss.
Effectively, former alopecia director makes new advances that fermentation amasss is more than 40%.
Invalid, it is less than 40% that former alopecia director makes new advances that fermentation amasss.
Therapeutic outcome:
Clinical cure 258 example (86%), effective 36 examples (12%), invalid 6 examples (2%), total effective rate is 98%.
Although embodiment of the present invention are disclosed as above, but it is not restricted in description and embodiment listed fortune
With, it can be applied to various applicable the field of the invention completely, for those skilled in the art, and can be easily
Realizing other amendment, therefore under the general concept limited without departing substantially from claim and equivalency range, the present invention does not limit
In specific details with shown here as the embodiment with description.
Claims (7)
1. the Chinese medicine preparation preventing alopecia, it is characterised in that described Chinese medicine preparation is by elite extracting solution and concentration
Cream forms;
Wherein, described elite extracting solution includes the raw material of following weight portion meter: 10-13 part Caulis Seu Folium Euonymi Fortunei, 10-13 part Semen Persicae, 8-10
Part Semen Sesami Nigrum, 20-25 part Herba Leonuri, 5-7 part Herba Agrimoniae, 3-7 part gray gum, the white Radix Polygoni Multiflori of 9-12 part, 3-7 part June
Snow and 3-7 part Radix Ginseng;
Described condensed cream includes the raw material of following weight portion meter: 1-2 part Fructus Rubi, 3-5 part Salix Babylonica L.P.E, 3-5 part mountain
Clausena lansium (Lour.) Skeels, 3-5 part Cornu Bovis seu Bubali, 8-10 part Cortex Ziziphi spinosae Radicis, 1-2 part Radix Rubiae, 3-5 part lavandula angustifolia, 3-5 part Cortex et Radix Polygalae (processed) and 3-5 part
Fructus Mori.
Prevent the Chinese medicine preparation of alopecia the most as claimed in claim 1, it is characterised in that described Caulis Seu Folium Euonymi Fortunei, described
Semen Persicae, described Semen Sesami Nigrum, described Herba Leonuri, described Herba Agrimoniae, described gray gum, described white Radix Polygoni Multiflori, described Serissa foetida
80 mesh sieves were pulverized respectively with described Radix Ginseng.
Prevent the Chinese medicine preparation of alopecia the most as claimed in claim 2, it is characterised in that described elite extracting solution
Preparation method comprises the following steps:
A1: by the Caulis Seu Folium Euonymi Fortunei of above-mentioned parts by weight, Herba Leonuri, Semen Sesami Nigrum and Semen Persicae mix homogeneously, obtain the first mixed-powder,
In described first mixed-powder, add the water of its 4-5 times of quality, slow fire boiling 4-6h, be 11000 dalton with molecular weight
Ultrafiltration membrance filter, obtain the first filtrate;
A2: by the Herba Agrimoniae of above-mentioned parts by weight, gray gum, white Radix Polygoni Multiflori, Serissa foetida and Radix Ginseng mix homogeneously, obtain second
Mixed-powder, the yellow wine of the quality such as addition in described second mixed-powder, soaks 5-7 days at 35 DEG C, with molecular weight is
11000 daltonian ultrafiltration membrance filters, obtain the second filtrate;
A3: the first filtrate and the second filtrate are mixed, obtains described elite extracting solution.
Prevent the Chinese medicine preparation of alopecia the most as claimed in claim 2, it is characterised in that the preparation of described condensed cream
Method comprises the following steps:
B1: by the Fructus Rubi of above-mentioned weight portion, Salix Babylonica L.P.E, Cortex Clausenae Excavatae, Cornu Bovis seu Bubali, Radix Rubiae, lavandula angustifolia, Cortex et Radix Polygalae (processed)
Being dried to water content with Fructus Mori is less than 10%, pulverized 80 mesh sieves, and obtained xeraphium;
B2: by the acetone soln reflux, extract, that described xeraphium volume fraction is 70%, Extracting temperature is set to 65 DEG C
-75 DEG C, extraction time is 4 hours, extracts 1-2 time, and united extraction liquid obtains xeraphium extracting solution;
B3: by described xeraphium extracting solution concentrating under reduced pressure, and reclaim acetone solvent, obtain thick paste;
B4: by the Cortex Ziziphi spinosae Radicis extraction by steam distillation Cortex Ziziphi spinosae Radicis volatile oil of above-mentioned weight portion;
B5: described thick paste and the described Cortex Ziziphi spinosae Radicis volatile oil that takes are mixed, obtains described condensed cream.
Prevent the Chinese medicine preparation of alopecia the most as claimed in claim 4, it is characterised in that described B3 reduces pressure dense
Contracting pressure be-0.075MPa, temperature is 58 DEG C.
Prevent the Chinese medicine preparation of alopecia the most as claimed in claim 2, it is characterised in that described elite extracted
Liquid and described condensed cream mix for 1:3-5 in mass ratio, obtain the 3rd mixture, will join with water-dispersible sodium alginate
In described 3rd mixture, and it is stirred continuously to described 3rd mixture surface formation layer of gel, obtains described Chinese medicine system
Agent.
Prevent the Chinese medicine preparation of alopecia the most as claimed in claim 6, it is characterised in that described Chinese medicine preparation is
Capsule preparations.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN113057927A (en) * | 2021-03-29 | 2021-07-02 | 中科瑞晟芳香产业研究院(湖北)有限公司 | Hair-strengthening shampoo containing aromatic Chinese herbal medicines |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1087267A (en) * | 1992-11-23 | 1994-06-01 | 梅晓春 | A kind of prescription for the treatment of seborrheic alopecia |
CN101293040A (en) * | 2008-06-06 | 2008-10-29 | 思雪花 | Chinese medicine for generating and nourishing hair |
CN104689285A (en) * | 2015-03-31 | 2015-06-10 | 刘凤伟 | Traditional Chinese preparation for treating alopecia |
CN104984141A (en) * | 2015-07-29 | 2015-10-21 | 张光泉 | Prescription for treating constipation and preparation method thereof |
CN105596940A (en) * | 2015-12-26 | 2016-05-25 | 薛学明 | Drug for treating alopecia and preparation method thereof |
-
2016
- 2016-05-27 CN CN201610362756.XA patent/CN105920170A/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1087267A (en) * | 1992-11-23 | 1994-06-01 | 梅晓春 | A kind of prescription for the treatment of seborrheic alopecia |
CN101293040A (en) * | 2008-06-06 | 2008-10-29 | 思雪花 | Chinese medicine for generating and nourishing hair |
CN104689285A (en) * | 2015-03-31 | 2015-06-10 | 刘凤伟 | Traditional Chinese preparation for treating alopecia |
CN104984141A (en) * | 2015-07-29 | 2015-10-21 | 张光泉 | Prescription for treating constipation and preparation method thereof |
CN105596940A (en) * | 2015-12-26 | 2016-05-25 | 薛学明 | Drug for treating alopecia and preparation method thereof |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN113057927A (en) * | 2021-03-29 | 2021-07-02 | 中科瑞晟芳香产业研究院(湖北)有限公司 | Hair-strengthening shampoo containing aromatic Chinese herbal medicines |
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Application publication date: 20160907 |