CN105902899A - Wind-dispelling Qianzheng mixture, as well as method and equipment thereof - Google Patents

Wind-dispelling Qianzheng mixture, as well as method and equipment thereof Download PDF

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CN105902899A
CN105902899A CN201610485105.XA CN201610485105A CN105902899A CN 105902899 A CN105902899 A CN 105902899A CN 201610485105 A CN201610485105 A CN 201610485105A CN 105902899 A CN105902899 A CN 105902899A
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housing
radix
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stream cover
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周仲瑜
黄伟
李家康
焦杨
韦丹
邓杰
陈霞
高锋
宋爱群
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Li Jiakang
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238—Saposhnikovia
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/19—Acanthaceae (Acanthus family)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/237—Notopterygium
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/534—Mentha (mint)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/752—Citrus, e.g. lime, orange or lemon
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8998—Hordeum (barley)
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The invention discloses a wind-dispelling Qianzheng mixture, as well as a method and equipment thereof. The mixture is prepared from the following medicinal raw materials in parts by weight: 8-12 parts of radix saposhnikoviae, 8-12 parts of radix angelicae, 8-12 parts of herba schizonepetae, 8-12 parts of incised notopterygium, 8-12 parts of peppermint, 13-17 parts of lonicera japonica, 13-17 parts of fructus forsythiae, 13-17 parts of radix isatidis, 18-22 parts of rhizoma phragmitis, 4-8 parts of radix bupleuri, 8-12 parts of honey-fried licorice root, 8-12 parts of silkworm larva, 4-8 parts of pericarpium citri reticulatae, 13-17 parts of roasted rice sprouts and 13-17 parts of roasted malt. The wind-dispelling Qianzheng mixture has main effects of dispelling wind, eliminating evil factors, clearing and activating the channels and collaterals, and is mainly used for treating facial paralysis, especially the facial paralysis in the acute phase with symptoms of superficies attacked by exterior evil and unsolved exterior evil.

Description

Dispel the wind and lead positive mixture and method and apparatus thereof
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly relate to dispeling the wind of a kind of facial paralysis and lead positive mixture.
Background technology
Facial paralysis, formal name used at school facial paralysis, also referred to as facial neuritis, bell's palsy, hunter syndrome, it is commonly called as " wapperijaw bar ", " wapperijaw ", " facial paralysis ", " hanging skew wind ", " facial neuritis ", " wapperijaw wind " etc., being a kind of commonly encountered diseases with facial expression muscle group dyskinesia as principal character, general symptom is facial hemiparalysis.
Facial paralysis is common clinical, and document report sickness rate in various countries' is in 30-70/10 ten thousand populations/year, and the patient that must cross facial paralysis in Chinese has ten million, and annual new fermentation paralysis patient is more than 400,000 people.What can suffer from facial paralysis at the age.Do not include neonate obstetric forceps to crush, just birth 29 days minimum in patient, maximum 91 years old.But it is more within about 40 years old, to fall ill.Old man Beijing-Tianjin area about 70 years old is also susceptible to suffer from this disease, and men and women's disease rates is about 1:1.It is the highest that face paralysis sends out rate, the most in the winter time, owing to being winter, is also various disease season occurred frequently in weather changeable and dry season, so, facial paralysis is the most just easy to disease.
Modern medicine thinks that the cause of disease to primary disease and pathogenesis illustrate the most completely, spasm, ischemia, edema is there is in the blood vessel that great majority are considered because virus infects and cold stimulation makes supply neural because stimulating, again because being limited by surrounding long and narrow sclerotin neurocele, nervus facialis pressurized is made to occur.
Western medical treatment Bei Ershi facial paralysis is mainly medicine and two kinds of methods of operation, what the dispute of its drug treatment was more is the use problem of hormone, but actually, outside expanding blood vessel medicine and neurotrophy medicine, steroid drugs (SD) is used almost to have become as pandemic method in a large number in early days.Kinishi etc. are thought by many cases case Ureteral Calculus, and application SD curative effect is preferable.Compared with using vitamin and medicament for expanding vascellum, the complete Bei Ershi facial paralysis 87% of application SD treatment is recovered completely, and carries out vitamin and expand blood vessel medicine therapist, and only 68% is cured.Operative treatment facial paralysis is general the most just implements operation, needs patient meninges and the brain of patient to be pressed into intracranial in operation, and patient is postoperative to be also needed to ICU ward mornitoring one day.This operative therapy requires height the most very to technology and equipment, and expensive, is difficult to be widely popularized clinically, and it is disadvantageous in that operation risk is big, and medical expense is high, can bring the misery of operation to patient, and effect is the most undesirable.
Acupuncture in the traditional Chinese medical science, moxibustion therapy, rubbing hot medicated compress, outward apply medicinal lotion or ointment thing etc., for conventional method, enriched again the multiple acupuncture-moxibustion therapy methods such as acusector, acupoint injection therapy, composite treatment modern age, and facial paralysis curative effect is preferable, is widely deployed in clinical practice.There is no patent medicine listing facial paralysis in the market, facial paralysis mixture can effectively replace Chinese medicine decoction, can exempt trouble of boiling medicine, it is simple to carry, i.e. convenient the most effective.In view of the highest sickness rate, the wide coverage rate at age, accounts for the present situation of main population, and the inconvenience of existing market Chinese medicine decoction with young working clan, facial paralysis mixture can the effectively economic misery solving many patients easily, and it is more cheap easy to compare traditional decocting medicine mode.
Summary of the invention
It is an object of the invention to for the deficiencies in the prior art, it is provided that positive mixture is led in dispeling the wind of a kind of facial paralysis, have that therapeutic effect is notable, treatment cycle is short, have no side effect, the feature such as easy to carry.
The invention provides the Chinese medicine composition of a kind of facial paralysis, be made up of the crude drug of following weight portion:
Radix Saposhnikoviae 8-12 part, Radix Angelicae Dahuricae 8-12 part, Herba Schizonepetae 8-12 part, Rhizoma Et Radix Notopterygii 8-12 part, Herba Menthae 8-12 part, Flos Lonicerae 13-17 part, Fructus Forsythiae 13-17 part, Radix Isatidis 13-17 part, Rhizoma Phragmitis 18-22 part, Radix Bupleuri 4-8 part, Radix Glycyrrhizae Preparata 8-12 part, Bombyx Batryticatus 8-12 part, Pericarpium Citri Reticulatae 4-8 part, fry two buds each 13-17 part.
Preferably, the Chinese medicine composition of described facial paralysis, it is made up of the crude drug of following weight portion:
Radix Saposhnikoviae 10 parts, the Radix Angelicae Dahuricae 10 parts, Herba Schizonepetae 10 parts, Rhizoma Et Radix Notopterygii 10 parts, Herba Menthae 10 parts, Flos Lonicerae 15 parts, Fructus Forsythiae 15 parts, Radix Isatidis 15 parts, Rhizoma Phragmitis 20 parts, Radix Bupleuri 6 parts, Radix Glycyrrhizae Preparata 10 parts, Bombyx Batryticatus 10 parts, Pericarpium Citri Reticulatae 6 parts, fry each 15 parts of two buds.
Wherein, Radix Saposhnikoviae: expelling pathogenic wind from the body surface, removing dampness to relieve pain, spasmolytic is antipruritic.
The Radix Angelicae Dahuricae: warm in nature, acrid in the mouth, return lung, spleen, stomach warp, there is relieving exterior syndrome and dispelling cold, wind-expelling pain-stopping, clearing the nasal passage, dampness leukorrhagia stopping, effect of detumescence and apocenosis, cure mainly headache, supraorbital bone pain, toothache, nasal sinusitis, the cards such as cold-damp is suffered from abdominal pain, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.
Herba Schizonepetae: deliver scattered wind, rash, belong to the pungent and warm medicine for relieving the exterior syndrome of diaphoretic medicine subordinate classification.
Rhizoma Et Radix Notopterygii: for impotence and seminal emission, enuresis frequent micturition, chills and pain of the waist and kness, suffer from a deficiency of the kidney and breathe heavily, Diarrhoea；External curing vitiligo, alopecia areata；Affection of exogenous wind-cold, have a headache lossless, mimeograph cold-damp numbness, edema due to wind pathogen edema, sore swollen toxin.
Herba Menthae: be pungent cool property sweating antipyretic medicine, controls influenza, the disease such as headache, conjunctival congestion, fever of the body, throat, dental bed swell and ache.External can training the mind dysmenorrhoea, skin pruritus, erythra and eczema etc..
Flos Lonicerae: cold in nature, sweet in the mouth, enter lung, the heart, stomach warp, there is heat-clearing and toxic substances removing, antiinflammatory, qi-restoratives treat effect of wind, cure mainly disease under distension, epidemic febrile disease heating, the disease such as pyretic toxicity carbuncle and ulcer and tumor.
Fructus Forsythiae: nature and flavor are bitter, cool.It is included into the heart, liver, gallbladder meridian.Cure mainly heat clearing away, removing toxic substances, eliminating stagnation, detumescence.Control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.
Radix Isatidis: cold in nature, taste is the most micro-sweet rear pained, has the effect of heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, relieving sore throat and pain.
Rhizoma Phragmitis: nature and flavor: sweet, cold.Return lung meridian, stomach warp.For calentura excessive thirst, gastropyretic vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.
Radix Bupleuri: acrid in the mouth, hardship, cold nature.Return liver, gallbladder, lung meridian.For reconciling superficies and interior, dispersing the stagnated live-QI to relieve the stagnation of QI, ascending up spleen-Qi and Yang, preventing the attack (or recurrence) of malaria of bringing down a fever.
Radix Glycyrrhizae Preparata: sweet in the mouth, property is put down, nontoxic.Function cures mainly: treating disorders in five ZANG-organs six internal organs cold and heat pathogen, hard muscles and bones, long muscle, times strength, and removing toxic substances, clothes are made light of one's life by commiting suicide and prolonged life for a long time.Raw by pathogenic fire purging heat, ripe with dissipating exterior cold, go pharyngalgia, evil removing heat, slow healthy energy, yin nourishing blood, tonifying the spleen and stomach, lung moistening.
Bombyx Batryticatus: acrid in the mouth, salty, property is put down, is returned liver, lung, stomach warp, have expelling wind to relieve convulsion, dissipating phlegm and resolving masses, effect of heat-clearing and toxic substances removing dampness, cures mainly convulsion with spasms, laryngopharynx swelling and pain, the cards such as submandibular lymph nodes is scorching, facial paralysis, skin pruritus.
Pericarpium Citri Reticulatae: return lung, spleen channel.For distension and fullness in the abdomen, lack of appetite and vomiting, cough with copious phlegm.
Frying two buds: wherein Fructus Hordei Germinatus (parched), cure mainly food stagnation and do not disappear, abdominal distention, insufficiency of the spleen lack of appetite, breast antiperspirant smoulders, distending pain of the breast, and women weans.Wherein Fructus Setariae Germinatus (parched) is sweet, temperature, enters spleen, stomach warp, controls indigestion, distension, have loose bowels, anorexia.
It is presently believed that facial paralysis be during collaterals being void and defenceless, ailment said due to cold or exposure enter, the resistance of QI and blood numbness and there is facial hemiparalysis.In facial paralysis mixture, the pungent temperature of Radix Saposhnikoviae dissipates, and can discongest the heresy at table, and the Radix Angelicae Dahuricae, Herba Schizonepetae, Rhizoma Et Radix Notopterygii abnormal smells from the patient all rise, and can discongest the heresy at table, " main flesh table eight winds coming from eight orientations harmful climatic factors ", and " controlling harmful wind, actinal surface is evil ", four medicines are combined into monarch.Flos Lonicerae, Fructus Forsythiae, Radix Isatidis, Herba Menthae, Rhizoma Phragmitis heat-clearing and toxic substances removing, dispelling wind and heat pathogens, the effect of removing heat from blood, Bombyx Batryticatus has to walk to alter stimulates the menstrual flow, and reduce phlegm relieving convulsion, the effect of the wind can dispelled in network, Radix Bupleuri has a liter act yang-energy, and seven medicines share sensible face venation QI and blood, and the duty of ministerial drug carried on a shoulder pole altogether by all medicines.Pericarpium Citri Reticulatae, fry two bud energy regulating qi-flowing for harmonizing stomach, promote QI-blood circulation, share altogether for the assistant in side.
Dispelling face pathogenic factor in the exterior with the agent dispeled the wind in a large number in side's medicine of the present invention, primary efficacy is to dispel the wind to dissipate heresy, dredge the meridian passage, and cures mainly face paralysis, and especially facial paralysis acute stage exopathogen attacks table, the disease that pathogenic factor in the exterior does not solves.The present invention is with classical theory for this, with clinical efficacy as root, and elite side's medicine that facial paralysis mixture is summed up during facial paralysis disease for many years, all achieve good curative effect for treating the facial paralysis of various pattern of syndrome.The present invention selects natural Chinese medicinal herb, for facial paralysis instant effect, has determined curative effect, has no side effect, low cost, short treating period, the feature that cure rate is high.
Present invention also offers and a kind of led positive mixture by dispeling the wind of making of the Chinese medicine composition of above-mentioned facial paralysis, described in dispel the wind and lead positive mixture and include oral liquid, tablet, capsule, pill etc., preferred dosage form is oral liquid, three times on the one, and point morning, noon and afternoon take for three times.
The Chinese medicine composition of the present invention can be prepared as multiple dosage form.Such as, pack after the medicinal liquid sterilizing after decocting, make oral liquid；Or the medicinal liquid after decocting concentrates, and after drying, adds the most receivable adjuvant, then makes tablet, capsule, pill etc..
The most receivable described adjuvant includes starch, dextrin, sodium carboxymethyl cellulose, Polyethylene Glycol, calcium hydrogen phosphate, sodium alginate, potassium sorbate etc., cane sugar powder.
Present invention also offers a kind of described in dispel the wind and lead the preparation method of positive mixture, comprise the following steps: pack after the medicinal liquid sterilizing after decocting, make oral liquid；Or the medicinal liquid after decocting concentrates, and after drying, adds the most receivable adjuvant, then makes tablet, capsule, pill, oral liquid, granule etc..
Preferably, described preparation method comprises the following steps:
A, each Chinese medicine ingredients are by raw material: weight ratio 1:30-50 of water add water respectively decoct three times, the most each 20 minutes；
B, merge each medicinal liquid, filtering residue；
C, concentrate filtrate to be the thick paste of 1.2 1.35 for density relatively, drying under reduced pressure,
D, thick paste after the drying add the most receivable adjuvant, pelletizes, be dried；
E, need to be prepared as required dosage form according to preparation formulation.
Present invention also offers the application in preparing facial paralysis medicine of the described Chinese medicine composition.
The Chinese medicine composition of the present invention was a course for the treatment of with 7 days, according to the order of severity of the facial paralysis state of an illness, treated 1,2,3 or 4 courses for the treatment of.
According to the Chinese medicine composition of facial paralysis of the present invention, cooperate between each raw material, coordinate, facial paralysis is had good curative effect.
The oral liquid that Chinese medicine composition according to the present invention is made, good stability, bioavailability is high, and treatment cycle is short, instant effect, and cure rate is high.
The present invention dispels the wind and leads the equipment of positive mixture, it is characterised in that include housing, feed pipe, funnel, current controlled switch, the first expansion stream cover, the second expansion stream cover, permeability cell, storage cream pond, the pump housing, shower nozzle；nullDescribed case top is provided with feed pipe，The discharging opening of described feed pipe just bottom to housing，The funnel being fixedly connected with the casing it is provided with on the downside of feed pipe，Described funnel includes the cylindrical drum being positioned at upside and is positioned at the first frustum cone cylinder of downside，Funnel bottom is provided with filter screen，Described first frustum cone cylinder for up big and down small truncated cone-shaped，It is provided with current controlled switch between described cylindrical drum and the first frustum cone cylinder，Described current controlled switch is for controlling the opening and closing of feed pipe，The bottom of described funnel has communicated therewith the first expansion stream cover，Described first expands stream covers for up-small and down-big truncated cone-shaped，First expands stream cover bottom is fixed with the second expansion stream cover，Described second expands stream covers for up-small and down-big truncated cone-shaped，The gradient of the described first side expanding stream cover is more than the gradient of the side of the second expansion stream cover，The inner peripheral surface of the second outer face and housing expanding stream cover is fixed，Described housing bottom is provided with through hole，Described through hole is just to storage cream pond，The position of 2/3 height in described storage cream pond is provided with the pump housing，The described pump housing is connected with shower nozzle by connecting tube，Described shower nozzle is positioned at housing and is positioned at the underface of the second expansion stream cover，Permeability cell it is provided with on the downside of shower nozzle，Described permeability cell is fixed with housing，The ventilation mouth of described permeability cell is positioned at the outside of housing，Described permeability cell from up to down tilts；Described first expanding stream cover, second expand stream cover and include the outer layer being made up of 304 rustless steels, the middle level being made up of temperature regulating device, the internal layer be made up of carbon fiber from outside to inside, described temperature regulating device includes outer housing, frictional heat portion and connects sheet；Described frictional heat portion includes motor and the Corii Caprae seu Ovis of the output shaft being wrapped in motor；Described outer housing has between outer layer and internal layer；Many described frictional heat portions are fixedly mounted in described outer housing, and the outer surface of the Corii Caprae seu Ovis in described frictional heat portion is fixed by the inner surface of latex with housing；At least three it is provided with for accommodating the heating groove in described frictional heat portion in described outer housing；One end of the end of the close output shaft of described frictional heat portion Corii Caprae seu Ovis is provided with the nut directly contacted with output shaft, and described nut is connected with housing by plain washer, spring washer；Described connection sheet is copper sheet.
Accompanying drawing explanation
Fig. 1 is that the application dispels the wind the structural representation of the equipment leading positive mixture.
Detailed description of the invention
Below in conjunction with embodiment, the Chinese medicine composition of the facial paralysis of the present invention is elaborated.It will be obvious to those skilled in the art that following preferred embodiment is merely cited for, and it is not construed as limiting the invention.
In the present invention, if not refering in particular to, all of part, percentage ratio are unit of weight, and all of equipment and raw material etc. are all commercially available or the industry is conventional.Method in following embodiment, if no special instructions, is the conventional method of this area.
One, the preparation of Chinese medicine composition
Embodiment 1
(1) raw material of Chinese medicine of following weight is taken
Radix Saposhnikoviae 10g, Radix Angelicae Dahuricae 10g, Herba Schizonepetae 10g, Rhizoma Et Radix Notopterygii 10g, Herba Menthae 10g, Flos Lonicerae 15g, Fructus Forsythiae 15g, Radix Isatidis 15g, Rhizoma Phragmitis 20g, Radix Bupleuri 6g, Radix Glycyrrhizae Preparata 10g, Bombyx Batryticatus 10g, Pericarpium Citri Reticulatae 6g, fry the two each 15g of bud.
(2) take the crude drug of above-mentioned weight, add decocting in water 20 minutes, boil three merging filtrates, concentrate and prepare oral liquid.
Embodiment 2
(1) raw material of Chinese medicine of following weight is taken
Radix Saposhnikoviae 8g, Radix Angelicae Dahuricae 8g, Herba Schizonepetae 12g, Rhizoma Et Radix Notopterygii 12g, Herba Menthae 8g, Flos Lonicerae 13g, Fructus Forsythiae 17g, Radix Isatidis 17g, Rhizoma Phragmitis 18g, Radix Bupleuri 8g, Radix Glycyrrhizae Preparata 8g, Bombyx Batryticatus 8g, Pericarpium Citri Reticulatae 4g, fry the two each 15g of bud.
(2) take the crude drug of above-mentioned weight, add decocting in water 20 minutes, boil three merging filtrates, concentrate and prepare oral liquid.
Embodiment 3
(1) raw material of Chinese medicine of following weight is taken
Radix Saposhnikoviae 12g, Radix Angelicae Dahuricae 10g, Herba Schizonepetae 12g, Rhizoma Et Radix Notopterygii 8g, Herba Menthae 8g, Flos Lonicerae 17g, Fructus Forsythiae 17g, Radix Isatidis 13g, Rhizoma Phragmitis 22g, Radix Bupleuri 4g, Radix Glycyrrhizae Preparata 12g, Bombyx Batryticatus 8g, Pericarpium Citri Reticulatae 6g, fry the two each 17g of bud.
(2) take the crude drug of above-mentioned weight, add decocting in water 2 hours, then filter, prepare oral liquid.
The preparation of the present invention is not limited to above-mentioned oral liquid, it is possible to making other dosage forms, such as, the medicinal liquid after decocting concentrates, and after drying, adds the most receivable adjuvant, then makes tablet, capsule, pill, granule etc..
Two, test examples
For further illustrating the effect of the Chinese medicine composition of the present invention, facial paralysis patient is treated by the oral liquid utilizing embodiment 1 to prepare.
Prepared by the present invention dispel the wind leads positive mixture and is mainly used in peripheral facial paralysis, " Chinese medical disease diagnosis and the criterion of therapeutical effect " that its symptom is promulgated with reference to State Administration of Traditional Chinese Medicine, clinical manifestation is that mouth eye is oblique, slobbering, Ipsilateral volume stricture of vagina, disapperance of nasolabial sulcus or shoal, catacleisis can not, or with mastoid region tenderness, external auditory meatus herpes etc..Concrete clinical data sees the description below.
One, clinical data
1, physical data
200 example patients derive from Hubei Provincial Hospital of TCM's department of acupuncture and moxibustion, are the Peripheral Facial Paralysis Patients being in acute stage that October, in December, 2012 was accepted for medical treatment 2008.It is randomly divided into 2 groups: treatment group 100 example, male 52 examples, female 48 example；Year at age 26～52 (37.57 ± 10.72)；The course of disease 1～5d.Matched group 100 example, male 44 examples, female 56 example；Year at age 31～56 (39.70 ± 11.08), the course of disease 1～7d.Outpatient 54 example in wherein treatment group, inpatient 46 example, matched group outpatient 48 people, inpatient 52 people.Through statistical analysis, difference (the equal ＞ of P 0.05) that the physical data such as the age of 2 groups of patients, the course of disease, severity extent, outpatient service and number of hospitalized compares that there are no significant, there is comparability.
2, the diagnostic criteria of facial paralysis
(1) Western medicine diagnose standard
A () onset is unexpected；
B () Ipsilateral palpebral fissure is big, eyelid can not close, and sheds tears, and volume stricture of vagina disappears, it is impossible to frown；
(c) Ipsilateral nasolabial fold shoal or smooth, bicker is low and to strong side-lining；
(d) level diagnosis: infringement, in facial canal, in addition to facial muscle is paralysed, can have 2/3 dysgeusia, hyperacusis etc. before tongue.
(2) Syndrome Differentiation of Traditional Chinese Medicine
A () ailment said due to cold or exposure visitor is in meridians: facial hemiparalysis suddenly, can be with aversion to wind, heating, sweating or lossless, and limbs arrest tight, joint aches, have the accompanied symptoms such as tenderness under ear.Thin white fur of tongue, or BOHUANG, floating and tense pulse or floating number.
B () wind-phlegm enters network, passages through which vital energy circulates blocks: facial hemiparalysis, and mesh can not close, slobbering, is often accompanied by numb limbs and tense tendons, dizziness and nausea, coughs spit foam or feeling of oppression and fullness in the chest and epigastrium, stomachache vomiting.Pale tongue, tongue is the most greasy or whitens, stringy pulse or cunning.
(c) deficiency of both QI and blood, venation block: first bicker is numb, and continue then facial hemiparalysis, dizzy unable, lusterless complexion, lazy speech of losing heart, cardiopalmus sweating.Pale tongue, white and thin fur, thready pulse without strength.
3, inclusive criteria
(1) meet above diagnostic criteria, and level diagnosis is the patient's (in addition to facial muscle is paralysed, also the going down of 2/3 sense of taste before Ipsilateral tongue, check by five tastes bottle method) in facial canal；
(2) age is the patient in 16---65 year；
(3) course of disease is within 7 days, and medical before the patient that effectively treats；
(4) H B facial nerve functional classification is IV grade and V level level, and the patient that the scoring of Sunnybrook (Toronto) facial nerve function divides at 20--40.
4, exclusion standard
(1) do not meet diagnostic criteria, or sick position is facial canal outer (only facial muscle paralysis) or the patient that belongs to Hunt syndrome；
(2) patient of the peripheral facial paralysis of the diseases such as otitis media, parotitis, tumor it is secondary to:
(3) age patient less than 16 years old or more than 65 years old；
(4) course of disease is more than 7 days, or medical before once accepted the patient of effectively treatment:
5H-B facial nerve functional classification is in I～III level level, or the scoring of Sunnybrook (Toronto) facial nerve function is the patient less than 20 points or more than 40 points.
(5) serious diseases such as other serious cardiovascular, cerebrovascular, liver, kidney, lung and hemopoietic system and psychosis and puerperal patient are removed；
(6) being cautious use of or avoiding with disease except hormone: do not control the patients such as hyperglycemia, digestive tract ulcer, active tuberculosis, epilepsy, osteoporosis, corneal ulcer, extensive ulcer, fungal infection, drug-fast bacteria infection.
5, standard is rejected
(1) included in and be grouped, but therapeutic process has occurred herpes, having examined as Hunt syndrome person；
(2) included in and be grouped, after be diagnosed as the peripheral facial paralysis being secondary to other diseases (such as otitis media, tumor etc.):
(3) included in and be grouped, because a variety of causes fails to carry out treating by the therapeutic scheme of regulation and cause cannot be carried out the efficacy determination person of science.
6, come off standard
(1) meet inclusive criteria and be grouped, but because of a variety of causes person that is not fully complete this Ureteral Calculus, as occurred the person of having a fainting spell during acupuncture treatment during acupuncture, observation of curative effect records imperfect person；
(2) compliance is poor, serious adverse events or responder occur；
(3) not cooperate, bolter voluntarily.
Two, research method
200 example patients are derived from Hubei Provincial Hospital of TCM's department of acupuncture and moxibustion, it is the Peripheral Facial Paralysis Patients being in acute stage that October, in December, 2012 was accepted for medical treatment 2008, including in by appeal diagnostic criteria, be randomly divided into two groups, two groups of patients all give trophic nerve, improve the department of acupuncture and moxibustion conventional therapies such as circulation.Trophic nerve choice of drug cobamamide 1mg, intramuscular injection.Improve circulation choice of drug Safflower Yellow Injection injection 150mg, intravenous drip.Treatment group patient, on the basis of conventional therapy, takes facial paralysis mixture simultaneously, each 15ml, three times a day.Matched group is trophic nerve, improves circulation, acupuncture conventional therapy.2 groups is all 1 course for the treatment of with 7d, evaluates its curative effect after terminating 4 courses for the treatment of.If patient fully recovers before evaluation curative effect, stopped treatment the most in advance.
Three, efficacy assessment standard
According to " clinical common disease diagnosis and treatment standard ", the patient after treatment is carried out efficacy evaluation.
Recovery from illness: the symmetries such as facial muscle motion is the most normal, bilateral volume stricture of vagina nasolabial fold, without any discomfort sense.
Effective: facial muscle motion is clearly better earlier above, to close mesh and the drum cheek is normal, feed does not hinders, but when firmly doing expression action, two sided stricture of vagina is the most asymmetric；
Take a turn for the better: take a turn for the better seen from before facial muscle motion relatively treatment, but two sided stricture of vagina is the most asymmetric or closes mesh, feed dysfunction；
Invalid: to be not improved before and after treatment.
Data process and statistics
Four, data management
1, data management
(1) all MethodsThe cases enrolled all must complete case observation table.
(2) to all qualified and enter this test and fill in the patient of Informed Consent Form through screening, must all items conscientiously, in itemized record observation table, must not omit.
2, data process
After clinical trial end-of-job, data base hands over statistical analysis personnel carry out statistical analysis, statistic analysis result, hand over the principal investigator of this test to write out research report.
3, statistical analysis
Each medical enumeration data of different treatment groups uses frequency (constituting ratio) to carry out statistics and describes.Change before and after two groups of treatments uses X2 inspection, uses SPSS 16.0 software to carry out statistical analysis, the total effective rate that comparison therapy group is improved with matched group clinical symptoms, uses four fold table X2Inspection, α=0.05 is inspection level.Therapeutic outcome sees below group comparitive study example (%)
Come off analysis: two groups of total expulsion rates and the comparison of expulsion rate will use X due to adverse events2Inspection.
Table 1, treatment group compares with matched group efficacy result
Table 2, cures the comparison of number of cases between two groups
Through X2Inspection, treatment group is better than matched group, P < 0.05, has statistical significance, and treatment group cure rate is better than matched group.
Five, concrete case
Case 1: Jiang, man, 38 years old, patient suffered from face paralysis 8 days, and acupuncture-moxibustion are after 6 days, took Chinese medicine 1 of the present invention course for the treatment of simultaneously, and symptom is clearly better, acupuncture-moxibustion and the preparation taking the embodiment of the present invention 1, three times a day, each 15ml, fully recovers after 15 days, follows up a case by regular visits to 1 year not recur.
Case 2: Huang, female, 29 years old, after production still in suckling, first three sky of falling ill is in back scrape therapy, and aftersensation is slept front right side surface part nerve and twitched, saccade, choosing on lip, sleeping at night auris dextra root pain, distending pain is difficult to fall asleep unbearably, after rising morning, conscious right side face musculation is slow, muscle rigidity is uncontrolled, neck, waist, back are ached, the most tired, mood is low, just adjust.Falling ill and examined here later on 2nd, examine as the medium-sized facial paralysis of positive exogenous pathogen, oral administration Drug therapy of the present invention is fully recovered after one course for the treatment of.Follow up a case by regular visits to 1 year not recur.
Case 3: Hu, female, 47 years old, because operating pressure is big, facial paralysis occurred before January, local is had to have a cold invasion and attack history, unexpected slobbering, tiltedly, hypogeusia, hyperacusis, hypophasis, alleviates by taking the medicine 2 symptom course for the treatment of of the present invention, shares for 4 courses for the treatment of, and symptom eliminates.Follow up a case by regular visits to, do not recur.
As it is shown in figure 1, prepare the equipment of above-mentioned Bu Shen Zhuang waist cream, expand stream cover 104, second expand stream cover 105, permeability cell 107, storage cream pond 109, the pump housing 111, shower nozzle 106 including housing 108, feed pipe 101, funnel 102, current controlled switch 103, first；
nullDescribed housing 108 top is provided with feed pipe 101，The discharging opening of described feed pipe 101 just bottom to housing 108，The funnel 102 that be connected fixing with housing 108 it is provided with on the downside of feed pipe 101，Described funnel 102 includes the cylindrical drum being positioned at upside and is positioned at the first frustum cone cylinder of downside，It is provided with filter screen bottom funnel 102，Described first frustum cone cylinder for up big and down small truncated cone-shaped，Current controlled switch 103 it is provided with between described cylindrical drum and the first frustum cone cylinder，Described current controlled switch 103 is for controlling the opening and closing of feed pipe 101，The bottom of described funnel 102 has communicated therewith the first expansion stream cover 104，Described first expansion stream cover 104 is up-small and down-big truncated cone-shaped，First expands stream cover 104 bottoms is fixed with the second expansion stream cover 105，Described second expansion stream cover 105 is up-small and down-big truncated cone-shaped，The gradient of the described first side expanding stream cover 104 is more than the gradient of the side of the second expansion stream cover 105，The inner peripheral surface of the second outer face and housing 108 expanding stream cover 105 is fixed，It is provided with through hole bottom described housing 108，Described through hole is just to storage cream pond 109，The position of 2/3 height in described storage cream pond 109 is provided with the pump housing 111，The described pump housing 111 is connected with shower nozzle 106 by connecting tube，Described shower nozzle 106 is positioned at housing 108 and is positioned at the underface of the second expansion stream cover 105，Permeability cell 107 it is provided with on the downside of shower nozzle 106，Described permeability cell 107 is fixed with housing 108，The ventilation mouth 110 of described permeability cell is positioned at the outside of housing 108，Described permeability cell 107 from up to down tilts；
Described first expands stream cover 104, second expands stream cover 105 and includes the outer layer being made up of 304 rustless steels, the middle level being made up of temperature regulating device, the internal layer be made up of carbon fiber from outside to inside, and described temperature regulating device includes outer housing, frictional heat portion and connects sheet；Described frictional heat portion includes motor and the Corii Caprae seu Ovis of the output shaft being wrapped in motor；
Described outer housing has between outer layer and internal layer；Many described frictional heat portions are fixedly mounted in described outer housing, and the outer surface of the Corii Caprae seu Ovis in described frictional heat portion is fixed by the inner surface of latex with housing；At least three it is provided with for accommodating the heating groove in described frictional heat portion in described outer housing；One end of the end of the close output shaft of described frictional heat portion Corii Caprae seu Ovis is provided with the nut directly contacted with output shaft, and described nut is connected with housing by plain washer, spring washer；Described connection sheet is copper sheet.
The present invention can make first expansion stream cover the 104, second expansion stream cover 105 generate heat and produce vibrations by above-mentioned frictional heat portion, thus drives housing 108 to shake, and makes atomization postadhesion flow in storage cream pond 109 at the ointment of housing 108 inner surface.
The present invention can pour the medicinal liquid merged into feed pipe 101 by said structure, feed pipe can carry out filtering residue by funnel, then the first expansion stream cover 104 and the second expansion stream cover 105 is utilized medicinal liquid to be dried, concentrates, and, the unnecessary moisture utilizing the pump housing 111 layering to be separated out carries out redrying, so that medicinal liquid becomes mastic by shower nozzle 106.It is noted that the redrying carried out in housing 108 by shower nozzle 106, the volatilization of medicinal liquid can be avoided to greatest extent, thus improve drug rate, reduce production cost.
Preferably, described filter screen uses polythene fishing net preparation technology, and filter screen includes dispensing, melt extrudes, cools down preliminary draft, drafting forming, rolling, line processed, knitmesh,
nullIt comprises the steps: super high molecular weight germane and high molecular polyolefine are mixed nitrile rubber resin concentrates in proportion，Masterbatch base material is nitrile rubber resin，Super high molecular weight germane content 2%～7%，High molecular nitrile rubber content 6%～9%，The wear-resistant masterbatch being blended in proportion and nitrile rubber resin carry out dispensing by weight proportion，The weight of wear-resistant masterbatch is the 7%～10% of nitrile rubber weight，The compound prepared is stirred and is melt extruded by plastic extruder，The fiber melt extruded is put in temperature 50～80 DEG C of tanks and is cooled down，Pre-draft multiple 7～9 times，Monfil after cooling carries out drawing-off，Drawing temperature is 130 DEG C～170 DEG C，Drafting multiple 15～19 times，The monofilament being drawn through is shaped，Setting temperature is 150 DEG C～210 DEG C，Relaxation shrinkage is 7%～10%，The monfil shaped on winder with winding tension 300 ± 30cN、Coiling speed 220 ms/min～250 ms/min is batched，Monofilament is made the twist 336～416 twists/m、A diameter of 10mm～15mm netting twine，Then it is spun into reticulate body with this netting twine.
Owing to ointment is with certain acidity, the most easily corroding filter screen, the present invention can be anticorrosive by the filter screen of above-mentioned material, improves its service life, it is to avoid its residue pollutes ointment, medicament.
nullPreferably，It is provided with an intermediate plate near described entrance in the described pump housing 111，A sleeve it is provided with in pump case between described intermediate plate and piston，The cavity of closing is formed between described sleeve and intermediate plate，A connecting shaft it is rotatablely equipped with on described sleeve，Described connecting shaft runs through described cavity，Described connecting shaft one end passes described sleeve，The other end passes described intermediate plate，It is positioned in the described connecting shaft of described cavity and is installed with a connection dish，It is provided with a floating disc at described intermediate plate with being connected between dish in described cavity，A platen it is provided with between described floating disc and intermediate plate，Described platen is provided with screw rod，Described screw rod passes described intermediate plate and threadeds with described intermediate plate，Some compression springs it are provided with between described platen and floating disc，Under described compression spring effect，Described floating disc offsets with the described dish end face that is connected，An impeller it is installed with in described connecting shaft，Described impeller passes described floating disc and described intermediate plate，On described impeller, circular array shows the blade of some radial arrangement，Feeding-passage is formed between blade described in adjacent two，Described feeding-passage is connected with described entrance，Described floating disc forms passage gaps with being connected between dish，Described sleeve is provided with the through hole that some and described passage gaps position is corresponding，Described through hole is connected with described feeding-passage by described passage gaps；Described connecting shaft passes one end of described sleeve and connects described piston by the power conversion mechanism being converted to the reciprocating motion of described piston drive described connecting shaft to rotate, the outer surface of described sleeve is slidably fitted with one for blocking the sleeve of described through hole, and described sleeve connects described piston by a connecting rod；Described pump case between described sleeve and piston is provided with an outlet, and described outlet connects a ball valve being controlled by described piston.
The present invention can enable the pump housing aspirate water and the ointment of half thickness by said structure, thus facilitates it to be transported at shower nozzle 106.
Preferably, described pump housing shower nozzle 106 includes nozzle housing, shower nozzle water inlet it is provided with in described nozzle housing, middle liquid pipe, second water pipe, first round platform atomizer, middle atomization chamber and the second round platform atomizer, the outlet of described first round platform atomizer connects with middle atomization chamber, described middle atomization chamber passes through pipe with spiral pipe and the inlet communication of the second round platform atomizer, the middle part of described pipe with spiral pipe connects radiation through holes, described nozzle housing is provided with for controlling the water inlet switch that shower nozzle water inlet only connects with middle liquid pipe or connects with middle liquid pipe and the first round platform atomizer simultaneously, the outlet switch that liquid pipe connects with the second water pipe and radiation through holes respectively or disconnects in controlling；
Described water inlet switch includes the injection changer lever being installed in nozzle housing with being flexibly connected, and described injection changer lever is provided with by being movably connected on the second switching hole and the first atomization slotted eye that connection shower nozzle water inlet with the first of middle liquid pipe the switching hole and makes shower nozzle water inlet connect by activity with middle liquid pipe and the first round platform atomizer simultaneously；Described outlet switch includes the fogging degree regulation changer lever being installed in nozzle housing with being flexibly connected, and described fogging degree regulation changer lever is provided with liquid pipe and the 3rd direct projection slotted eye of the second water pipe in only being connected by activity, by liquid pipe in movable only connection and the second atomization slotted eye of radiation through holes and by the seal washer of liquid pipe in movable disconnection；
Described injection changer lever and fogging degree regulation changer lever are equipped with movable stopper slot, and described nozzle housing is provided with the gag lever post being inserted in each movable stopper slot.
The present invention can switch different fogging degrees according to water and the different proportion of ointment, prevent shower nozzle from blocking.
Embodiment described above is only to be described the preferred embodiment of the present invention; not the scope of the present invention is defined; on the premise of designing spirit without departing from the present invention; various deformation that technical scheme is made by those of ordinary skill in the art and improvement, all should fall in the protection domain that claims of the present invention determines.

Claims (10)

1. a Chinese medicine composition for facial paralysis, is made up of the crude drug of following weight portion:
Radix Saposhnikoviae 8-12 part, Radix Angelicae Dahuricae 8-12 part, Herba Schizonepetae 8-12 part, Rhizoma Et Radix Notopterygii 8-12 part, Herba Menthae 8-12 part, Flos Lonicerae 13-17 part, Fructus Forsythiae 13-17 part, Radix Isatidis 13-17 part, Rhizoma Phragmitis 18-22 part, Radix Bupleuri 4-8 Part, Radix Glycyrrhizae Preparata 8-12 part, Bombyx Batryticatus 8-12 part, Pericarpium Citri Reticulatae 4-8 part, fry two buds each 13-17 part.
The Chinese medicine composition of facial paralysis the most according to claim 1, by the raw material of following weight portion Medicine forms:
Radix Saposhnikoviae 10 parts, the Radix Angelicae Dahuricae 10 parts, Herba Schizonepetae 10 parts, Rhizoma Et Radix Notopterygii 10 parts, Herba Menthae 10 parts, Flos Lonicerae 15 parts, Fructus Forsythiae 15 parts, Radix Isatidis 15 parts, Rhizoma Phragmitis 20 parts, Radix Bupleuri 6 parts, Radix Glycyrrhizae Preparata 10 parts, white Bombyx Batryticatus 10 parts, Pericarpium Citri Reticulatae 6 parts, fry each 15 parts of two buds.
3. lead positive mixture according to dispeling the wind of preparing of the Chinese medicine composition of one of claim 1-2.
The most according to claim 3 dispeling the wind leads positive mixture, it is characterised in that described in dispel the wind to lead and be just accord with Agent is powder, pill, tablet, capsule, patch, granule or oral liquid, preferred oral liquid.
5. dispel the wind described in an any one of claim 3-4 and lead the preparation method of positive mixture, it is characterised in that Comprise the following steps: pack after the medicinal liquid sterilizing after decocting, make oral liquid；Or will decoct After medicinal liquid concentrate, after drying, add the most receivable adjuvant, then make tablet, glue Wafer, pill, oral liquid, granule etc..
Preparation method the most according to claim 5, it is characterised in that comprise the following steps:
A, each Chinese medicine ingredients are by raw material: weight ratio 1:30-50 of water add water respectively decoct three times, respectively 20 minutes；
B, merge each medicinal liquid, filtering residue；
C, concentrate filtrate to be the thick paste of 1.2 1.35 for density relatively, drying under reduced pressure,
D, thick paste after the drying add the most receivable adjuvant, pelletizes, be dried；
E, need to be prepared as required dosage form according to preparation formulation.
7. a Chinese medicine composition as according to any one of claim 1-2 is preparing facial paralysis medicine In application.
8. dispeling the wind described in preparation claim 6 leads the equipment of positive mixture, it is characterised in that include housing (108), feed pipe (101), funnel (102), current controlled switch (103), first expand stream cover (104), Second expands stream cover (105), permeability cell (107), storage cream pond (109), the pump housing (111), shower nozzle (106)；
Described housing (108) top is provided with feed pipe (101), the discharging opening of described feed pipe (101) The just bottom to housing (108), feed pipe (101) downside is provided with to fix with housing (108) and is connected Funnel (102), described funnel (102) includes the cylindrical drum being positioned at upside and is positioned at the first round platform of downside Cylinder, funnel (102) bottom is provided with filter screen, described first frustum cone cylinder for up big and down small truncated cone-shaped, institute Stating and be provided with current controlled switch (103) between cylindrical drum and the first frustum cone cylinder, described current controlled switch (103) is used for Controlling the opening and closing of feed pipe (101), the bottom of described funnel (102) has communicated therewith first Expanding stream cover (104), described first expansion stream cover (104) is up-small and down-big truncated cone-shaped, and first expands stream covers (104) Bottom is fixed with the second expansion stream cover (105), and described second expansion stream cover (105) is up-small and down-big truncated cone-shaped, The gradient of the described first side expanding stream cover (104) expands inclining of the side of stream cover (105) more than second Gradient, the outer face of the second expansion stream cover (105) and the inner peripheral surface of housing (108) are fixed, described shell Body (108) bottom is provided with through hole, and described through hole is just to storage cream pond (109), described storage cream pond (109) The position of 2/3 height be provided with the pump housing (111), the described pump housing (111) is by connecting tube and shower nozzle (106) Connect, described shower nozzle (106) be positioned at housing (108) and be positioned at the second expansion stream cover (105) just under Side, shower nozzle (106) downside is provided with permeability cell (107), described permeability cell (107) and housing (108) Fixing, the ventilation mouth (110) of described permeability cell is positioned at the outside of housing (108), described permeability cell (107) From up to down tilt；
Described first expansion stream cover (104), the second expansion stream cover (105) and include from outside to inside by 304 rustless steels The outer layer made, the middle level being made up of temperature regulating device, the internal layer be made up of carbon fiber, described temperature regulating device Including outer housing, frictional heat portion and connection sheet；Described frictional heat portion includes motor and is wrapped in motor The Corii Caprae seu Ovis of output shaft；
Described outer housing has between outer layer and internal layer；Many described frictional heat portions are fixedly mounted on institute Stating in outer housing, the outer surface of the Corii Caprae seu Ovis in described frictional heat portion is fixed by the inner surface of latex with housing； At least three it is provided with for accommodating the heating groove in described frictional heat portion in described outer housing；Described friction is raw One end of the end of the close output shaft of hot portion Corii Caprae seu Ovis is provided with the nut directly contacted with output shaft, described Nut is connected with housing by plain washer, spring washer；Described connection sheet is copper sheet.
The most according to claim 8 dispeling the wind leads the equipment of positive mixture, it is characterised in that described filter screen Use polythene fishing net preparation technology, filter screen include dispensing, melt extrude, to cool down preliminary draft, drawing-off fixed Type, rolling, line processed, knitmesh,
It is fine that it comprises the steps: that super high molecular weight germane and high molecular polyolefine are mixed fourth in proportion Rubber resin masterbatch, masterbatch base material is nitrile rubber resin, super high molecular weight germane content 2%～7%, High molecular nitrile rubber content 6%～9%, the wear-resistant masterbatch being blended in proportion is pressed with nitrile rubber resin Part by weight carries out dispensing, and the weight of wear-resistant masterbatch is the 7%～10% of nitrile rubber weight, prepares Compound stir and melt extruded by plastic extruder, the fiber melt extruded put into temperature 50～ Cooling down in 80 DEG C of tanks, pre-draft multiple 7～9 times, the monfil after cooling carries out drawing-off, drawing-off temperature Degree is 130 DEG C～170 DEG C, drafting multiple 15～19 times, and the monofilament being drawn through is shaped, sizing temperature Degree is 150 DEG C～210 DEG C, and relaxation shrinkage is 7%～10%, the monfil shaped on winder with Winding tension 300 ± 30cN, coiling speed 220 ms/min～250 ms/min are batched, and monofilament is made the twist 336～416 twists/m, a diameter of 10mm～15mm netting twine, be then spun into reticulate body with this netting twine.
The most according to claim 8 dispeling the wind leads the equipment of positive mixture, it is characterised in that described pump It is provided with an intermediate plate near described entrance in body (111), sets in the pump case between described intermediate plate and piston There is a sleeve, form the cavity of closing between described sleeve and intermediate plate, described sleeve is rotatablely equipped with One connecting shaft, described connecting shaft runs through described cavity, and described connecting shaft one end passes described sleeve, another End passes described intermediate plate, is positioned in the described connecting shaft of described cavity and is installed with a connection dish, Being provided with a floating disc at described intermediate plate with being connected between dish in described cavity, described floating disc is with middle Being provided with a platen between plate, described platen is provided with screw rod, and described screw rod passes described intermediate plate and with described Intermediate plate is threaded, is provided with some compression springs between described platen and floating disc, at described compression bullet Under spring effect, described floating disc offsets with the described dish end face that is connected, and described connecting shaft is installed with one Impeller, described impeller passes described floating disc and described intermediate plate, and on described impeller, circular array is shown some The blade of radial arrangement, forms feeding-passage between blade described in adjacent two, described feeding-passage is with described Entrance is connected, and described floating disc forms passage gaps with being connected between dish, and described sleeve is provided with some The through hole corresponding with described passage gaps position, described through hole is by described passage gaps and described charging Passage is connected；Described connecting shaft passes one end of described sleeve by the reciprocating motion of described piston being turned The power conversion mechanism being changed to drive described connecting shaft to rotate connects described piston, the outer surface of described sleeve Being slidably fitted with one for blocking the sleeve of described through hole, described sleeve connects described piston by a connecting rod； Described pump case between described sleeve and piston is provided with an outlet, and described outlet connection one is controlled by described The ball valve of piston；
Preferably, described pump housing shower nozzle (106) includes nozzle housing, is provided with shower nozzle in described nozzle housing Water inlet, middle liquid pipe, the second water pipe, the first round platform atomizer, middle atomization chamber and the atomization of the second round platform Nozzle, the outlet of described first round platform atomizer connects with middle atomization chamber, and described middle atomization chamber passes through spiral shell Rotation water pipe and the inlet communication of the second round platform atomizer, the middle part connection of described pipe with spiral pipe have dissipate logical Hole, described nozzle housing be provided with for control shower nozzle water inlet only connect with middle liquid pipe or simultaneously with middle liquid pipe Connect with the first round platform atomizer water inlet switch, for control in liquid pipe respectively with the second water pipe and Radiation through holes connection or the outlet switch disconnected；
Described water inlet switch includes the injection changer lever being installed in nozzle housing with being flexibly connected, described Injection changer lever be provided with the first switching hole by being movably connected on connection shower nozzle water inlet and middle liquid pipe and Shower nozzle water inlet connect with middle liquid pipe and the first round platform atomizer simultaneously second is made to switch hole by activity With the first atomization slotted eye；Described outlet switch includes the atomization being installed in nozzle housing with being flexibly connected Degree regulation changer lever, described fogging degree regulation changer lever is provided with liquid Guan Yu in only being connected by activity 3rd direct projection slotted eye of two water pipes, the second atomization slotted eye by liquid pipe in movable only connection with radiation through holes And the seal washer of liquid pipe in being disconnected by activity；
Described injection changer lever and fogging degree regulation changer lever are equipped with movable stopper slot, described shower nozzle shell Body is provided with the gag lever post being inserted in each movable stopper slot.
CN201610485105.XA 2016-06-27 2016-06-27 Wind-dispelling Qianzheng mixture, as well as method and equipment thereof Withdrawn CN105902899A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100119606A1 (en) * 2001-05-04 2010-05-13 Gw Pharma Limited Processes and apparatus for extraction of active substances and enriched extracts from natural products
CN102198171A (en) * 2011-06-01 2011-09-28 刘学成 Traditional Chinese medicine preparation for mainly treating angina, prosopalgia and headache, and preparation method thereof
CN102560732A (en) * 2011-12-16 2012-07-11 杭州贝斯特化纤有限公司 Manufacturing technology for far-infrared polyester short fibers
CN105343383A (en) * 2014-08-21 2016-02-24 李新民 Formula for treating prosopoplegia

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100119606A1 (en) * 2001-05-04 2010-05-13 Gw Pharma Limited Processes and apparatus for extraction of active substances and enriched extracts from natural products
CN102198171A (en) * 2011-06-01 2011-09-28 刘学成 Traditional Chinese medicine preparation for mainly treating angina, prosopalgia and headache, and preparation method thereof
CN102560732A (en) * 2011-12-16 2012-07-11 杭州贝斯特化纤有限公司 Manufacturing technology for far-infrared polyester short fibers
CN105343383A (en) * 2014-08-21 2016-02-24 李新民 Formula for treating prosopoplegia

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
罗丽丹等: "姜玲主任医师治疗周围性面瘫经验", 《河南中医》 *

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