CN102198171A

CN102198171A - Traditional Chinese medicine preparation for mainly treating angina, prosopalgia and headache, and preparation method thereof

Info

Publication number: CN102198171A
Application number: CN 201110145869
Authority: CN
Inventors: 刘学成
Original assignee: 刘学成
Priority date: 2011-06-01
Filing date: 2011-06-01
Publication date: 2011-09-28
Anticipated expiration: 2031-06-01
Also published as: CN102198171B

Abstract

The invention relates a traditional Chinese medicine preparation for mainly treating angina, prosopalgia and headache, and a preparation method thereof. The traditional Chinese medicine preparation for mainly treating angina, prosopalgia and headache comprises raw materials of ligusticum wallichii, divaricate saposhnikovia roots, notopterygium roots, radix bupleuri, and schizonepeta, and is prepared by the above raw materials according to a certain parts by weight. The traditional Chinese medicine preparation has functions of relieving pain, tonifying qi, promoting blood circulation, removing blood stasis, regulating vital energy and dredging collaterals, and can relieve patients' pain. The invention has advantages of simple formula, sufficiency of raw materials, simple preparation, and low cost, and has unique curative effects to angina, prosopalgia and headache. The traditional Chinese medicine preparation can greatly reduce patients' pain, and reduce the economic burden of patients to the maximum extent.

Description

A kind of Chinese medicine preparation and preparation method that cures mainly angina pectoris, trigeminal neuralgia, headache

Technical field

The present invention relates to field of traditional Chinese, particularly a kind of Chinese medicine preparation and preparation method that cures mainly angina pectoris, trigeminal neuralgia, headache; This cures mainly in the raw material of Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache and contains Rhizoma Chuanxiong, Radix Saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Bupleuri, Herba Schizonepetae.

Background technology

Angina pectoris is a coronary insufficiency, and rapid, the temporary transient ischemia of cardiac muscle is caused with anoxia to be the clinical syndrome that mainly shows with ictal chest pain or chest discomfort.Its characteristics are paroxysmal shirtfront squeezing property pain perception, can be with other symptoms, and pain mainly is positioned at the breastbone rear portion, can be radiated to pareordia and left upper extremity, often betides work or when excited.

Prosopalgic cardinal symptom is or a highly branched ictal severe pain of face nervi trigeminus areal area, though the time of pain is comparatively of short duration, but usually send suddenly and violent take out pain, twinge, radiating pain, causalgia, lancinate sample or electric shock sample pain, simultaneously, can with shed tears, watery nasal discharge, be everlasting and speak, wash one's face, lured when chewing pain outbreak.Prosopalgic etiology and pathology is very complicated, and is not clear fully as yet so far.Trigeminal neuralgia not only is difficult to cure, and recurrence easily.

Headache is one of common clinically symptom, typically refers to be confined to the head first half, comprises geisoma, helix upper limb and the outer knuckle line of the pillow pain with the upper part.Headache is a human body to the various pain subjective sensations that factor produced that cause, and belongs to the category of pain.It can be physics, chemistry, biochemical or mechanical causing the pain factor, or the like.These factors have stimulated the sensory nerve ending that is arranged in the outer organizational structure of intracranial, pass to brain and perception by corresponding pathway.The reason of headache is various, and wherein some is serious fatal illness, but etiological diagnosis is often relatively more difficult.

More than the pathogeny complexity of several diseases, rapid onset, pain and is difficult to cure unbearably during outbreak.At present doctor trained in Western medicine adopts block therapy more or uses hormone and parahormone medicines such as ibuprofen or prednisone, though temporary transient disease controlling can't be effected a radical cure.

Therefore, need in the clinical treatment a kind of evident in efficacy, a kind of Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache that side effect is less, economic.

Summary of the invention

The objective of the invention is to study a kind of Chinese medicine preparation and preparation method that cures mainly angina pectoris, trigeminal neuralgia, headache; This cures mainly in the raw material of Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache and contains Rhizoma Chuanxiong, Radix Saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Bupleuri, Herba Schizonepetae; The present invention has pain relieving, QI invigorating, the effect of blood circulation promoting and blood stasis dispelling, regulating qi and dredging collateral.

The objective of the invention is to realize by following technical scheme:

A kind of Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, contain Rhizoma Chuanxiong, Radix Saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Bupleuri, Herba Schizonepetae in the raw material of the described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, described each raw material weight umber ratio that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache is:

Rhizoma Chuanxiong 2 ~ 11

Radix Saposhnikoviae 1 ~ 5

Rhizoma Et Radix Notopterygii 1 ~ 5

Radix Bupleuri 1 ~ 5

Herba Schizonepetae 1 ~ 5;

The described dosage form that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache can be powder, decoct, tablet, pill, capsule.

The Chinese medicine preparation function of described angina pectoris, trigeminal neuralgia, sciatica cures mainly: pain relieving, activating blood circulation and supplementing qi are applicable to angina pectoris, trigeminal neuralgia, headache, also applicable to symptoms such as sciatica, facial spasm, facial paralysis.

Another object of the present invention is achieved through the following technical solutions:

A kind of preparation method that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache, contain Rhizoma Chuanxiong, Radix Saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Bupleuri, Herba Schizonepetae in the raw material of the described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, described each raw material weight umber ratio that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache is:

Rhizoma Chuanxiong 2 ~ 11

Radix Saposhnikoviae 1 ~ 5

Rhizoma Et Radix Notopterygii 1 ~ 5

Radix Bupleuri 1 ~ 5

Herba Schizonepetae 1 ~ 5;

The described dosage form that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache is a powder, and preparation process is as follows:

A. raw material is handled

A. described Rhizoma Chuanxiong is cleaned processing, dried, pulverization process successively, obtain the Rhizoma Chuanxiong fine powder;

B. described Radix Saposhnikoviae is cleaned processing, dried, pulverization process successively, obtain the Radix Saposhnikoviae fine powder;

C. described Rhizoma Et Radix Notopterygii is cleaned processing, dried, pulverization process successively, obtain the Rhizoma Et Radix Notopterygii fine powder;

D. described Radix Bupleuri is cleaned processing, dried, pulverization process successively, obtain the Radix Bupleuri fine powder;

E. described Herba Schizonepetae is cleaned processing, dried, pulverization process successively, obtain the Herba Schizonepetae fine powder;

B. finished product preparation:

With described Rhizoma Chuanxiong fine powder, Radix Saposhnikoviae fine powder, Rhizoma Et Radix Notopterygii fine powder, Radix Bupleuri fine powder, Herba Schizonepetae fine powder,, obtain the described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache by above-mentioned weight proportion mix homogeneously; The described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache is carried out getting product after packing is handled.

Rhizoma Chuanxiong 2 ~ 11

Radix Saposhnikoviae 1 ~ 5

Rhizoma Et Radix Notopterygii 1 ~ 5

Radix Bupleuri 1 ~ 5

Herba Schizonepetae 1 ~ 5;

The described dosage form that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache is a decoct, and preparation process is as follows:

The A raw material is handled

B. finished product preparation:

The a mixed processing

With described Rhizoma Chuanxiong fine powder, Radix Saposhnikoviae fine powder, Rhizoma Et Radix Notopterygii fine powder, Radix Bupleuri fine powder, Herba Schizonepetae fine powder,, obtain raw material fine powder mixture by above-mentioned weight proportion mix homogeneously;

B decocts processing

Water with described raw material fine powder mixture adding constant weight umber decocts processing, can obtain the described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache; The described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache is carried out getting product after packing is handled.

Rhizoma Chuanxiong 2 ~ 11

Radix Saposhnikoviae 1 ~ 5

Rhizoma Et Radix Notopterygii 1 ~ 5

Radix Bupleuri 1 ~ 5

Herba Schizonepetae 1 ~ 5;

The described dosage form that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache is a tablet, and preparation process is as follows:

The A raw material is handled

B. finished product preparation:

A. mixed processing

B. with described raw material fine powder mixture and microcrystalline Cellulose, carboxymethyl starch sodium mixing, obtain total mixture; Described total mixture is carried out pelletization treatment, dried, obtain tablet mixture;

The ratio of weight and number that described microcrystalline Cellulose accounts for described total mixture is 0.02～0.05:100;

The ratio of weight and number that described carboxymethyl starch sodium accounts for described total mixture is 0.1～1:100;

In the described dried, temperature is 38～40 ℃;

C. with described tablet mixture and magnesium stearate mixing, obtain pressing mixt;

The ratio of weight and number that described magnesium stearate accounts for described pressing mixt is 0.15～1:100;

Described pressing mixt is carried out compression process, the Chinese medicinal tablet finished product of the angina pectoris that obtains medical treatment, trigeminal neuralgia, sciatica.

Rhizoma Chuanxiong 2 ~ 11

Radix Saposhnikoviae 1 ~ 5

Rhizoma Et Radix Notopterygii 1 ~ 5

Radix Bupleuri 1 ~ 5

Herba Schizonepetae 1 ~ 5

The described dosage form that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache is a pill, and preparation process is as follows:

The A raw material is handled

B. finished product preparation:

A. mixed processing

B. with described raw material fine powder mixture and Mel mixing, obtain the pill mixture; The ratio of weight and number of described raw material fine powder mixture and described Mel is 10:2～7;

C. described pill mixture is carried out mixing and handle, carry out again dried, cold preservation processing, dried, pill processing, promptly get the medicine pill finished product for the treatment of angina pectoris, trigeminal neuralgia, sciatica;

During described mixing was handled, temperature was 19～24 ℃;

During described cold preservation was handled, temperature was 13～20 ℃;

In the described dried, temperature is 35～37 ℃.

?

Rhizoma Chuanxiong 2 ~ 11

Radix Saposhnikoviae 1 ~ 5

Rhizoma Et Radix Notopterygii 1 ~ 5

Radix Bupleuri 1 ~ 5

Herba Schizonepetae 1 ~ 5

The described dosage form that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache is a capsule, and preparation process is as follows:

The A raw material is handled

B. finished product preparation:

A. mixed processing

B. with described raw material fine powder mixture and magnesium stearate mixing, obtain capsule 's content; The ratio of weight and number that described magnesium stearate accounts for described capsule 's content is 0.15～1:100; Again described capsule 's content is incapsulated in the housing, promptly get the Chinese medicinal capsule agent finished product for the treatment of angina pectoris, trigeminal neuralgia, sciatica.

Beneficial effect of the present invention is:

1, because the present invention with various raw material synergy, play unique therapeutical effect, so the present invention is applicable to multiple symptom: can pain relieving, QI invigorating, blood circulation promoting and blood stasis dispelling, regulating qi and dredging collateral, angina pectoris, trigeminal neuralgia, headache both be applicable to, again also applicable to symptoms such as sciatica, facial spasm, facial paralysis, premature beat, bradycardias.

2, the used prescription of the present invention is simple, the raw material abundance, and method for making is easy, and is cheap, economic and practical, can reduce patient's financial burden, is applicable to extensive popularization.

The specific embodiment

Embodiment 1:

Rhizoma Chuanxiong 2 ~ 11

Radix Saposhnikoviae 1 ~ 5

Rhizoma Et Radix Notopterygii 1 ~ 5

Radix Bupleuri 1 ~ 5

Herba Schizonepetae 1 ~ 5;

The described dosage form that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache can be a powder, hermetically storing; Usage is: one day 2 times, each 9 grams, eliminating cold for resuscitation mouth of a river clothes on an empty stomach, taking 7 days continuously is a course of treatment, general 2 the course of treatment symptom improvement is promptly arranged, general 6 the course of treatment symptom have clear improvement.

The dosage form of the Chinese medicine preparation of described angina pectoris, trigeminal neuralgia, sciatica can be decoct, tablet, pill, capsule, usage is: one day 2 times, each 9 grams, obey at the eliminating cold for resuscitation mouth of a river on an empty stomach, taking 7 days continuously is a course of treatment, general 2 the course of treatment symptom improvement is promptly arranged, general 6 the course of treatment symptom have clear improvement.

The Chinese medicine preparation function of described angina pectoris, trigeminal neuralgia, sciatica cures mainly:

Pain relieving, QI invigorating, blood circulation promoting and blood stasis dispelling, regulating qi and dredging collateral are applicable to angina pectoris, trigeminal neuralgia, headache, also applicable to sciatica, facial spasm, facial paralysis, premature beat, bradycardia symptom.

The theoretical basis of the above-mentioned raw materials that present embodiment is selected for use is:

Rhizoma Chuanxiong in the side: according to " Chinese pharmacopoeia is carried, the Rhizoma Chuanxiong nature and flavor: suffering, temperature; Gui Jing: return liver, gallbladder, pericardium channel; Effect: blood-activating and qi-promoting, wind-expelling pain-stopping; Cure mainly: be used for menoxenia. amenorrhea dysmenorrhea, mass in the abdomen stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.

Radix Saposhnikoviae in the side: according to " Chinese pharmacopoeia is carried, nature and flavor: hot, sweet. temperature; Gui Jing: return bladder, liver, spleen channel; Effect: inducing diaphoresis to dispel wind, win and wet, relieving convulsion; Cure mainly: be used for headache due to common cold, rheumatic arthralgia, rubella pruritus, tetanus.

Rhizoma Et Radix Notopterygii in the side: according to " Chinese pharmacopoeia is carried, nature and flavor: hot, bitter, and temperature; Gui Jing: return bladder, kidney channel; Effect: cold expelling, dispel the wind dehumidifying, pain relieving; Cure mainly: be used for the anemofrigid cold headache, rheumatic arthralgia, aching pain in should and back.

Radix Bupleuri in the side: according to " Chinese pharmacopoeia is carried, nature and flavor: hardship is slightly cold; Gui Jing: return liver, gallbladder meridian; Effect: reconciling superficies and interior, soothing the liver, yang invigorating; Cure mainly: be used for cold, fever. alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia; Uterine prolapse, proctoptosis.

Herba Schizonepetae in the side: according to " Chinese pharmacopoeia is carried, nature and flavor: suffering, tepor; Gui Jing: return lung, Liver Channel; Effect: the diffusing wind that induces sweat, rash; Cure mainly: be used for the flu, the headache, measles, rubella, skin infection from the beginning of.

In the present embodiment, above-mentioned 5 kinds of raw materials are handled through science, treated described disease according to the Chinese medical discrimination principle, utilize the dual regulation of Chinese medicine on the one hand, some imbalance of body can make that the pain increased, and Chinese medicine can make it balance; The traditional Chinese medical science has saying of " stagnation of QI and blood may bring about pain " on the other hand, adopt above-mentioned 5 kinds of raw materials can blood circulation promoting and blood stasis dispelling, regulating qi and dredging collateral, play the effect of " general rule is not bitterly ".

Rhizoma Chuanxiong 2 ~ 11

Radix Saposhnikoviae 1 ~ 5

Rhizoma Et Radix Notopterygii 1 ~ 5

Radix Bupleuri 1 ~ 5

Herba Schizonepetae 1 ~ 5;

B. raw material is handled

A. described Rhizoma Chuanxiong is cleaned processing, dried, pulverization process successively, obtain the Rhizoma Chuanxiong fine powder; Described dried temperature is 20 ~ 40 ℃, is preferably 30 ℃;

B. described Radix Saposhnikoviae is cleaned processing, dried, pulverization process successively, obtain the Radix Saposhnikoviae fine powder; Described dried temperature is 20 ~ 40 ℃, is preferably 30 ℃;

C. described Rhizoma Et Radix Notopterygii is cleaned processing, dried, pulverization process successively, obtain the Rhizoma Et Radix Notopterygii fine powder; Described dried temperature is 20 ~ 40 ℃, is preferably 30 ℃;

D. described Radix Bupleuri is cleaned processing, dried, pulverization process successively, obtain the Radix Bupleuri fine powder; Described dried temperature is 20 ~ 40 ℃, is preferably 30 ℃;

E. described Herba Schizonepetae is cleaned processing, dried, pulverization process successively, obtain the Herba Schizonepetae fine powder; Described dried temperature is 20 ~ 40 ℃, is preferably 30 ℃;

B. finished product preparation:

In the present embodiment, the consumption of each raw material in the described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache can be in the ratio range that provides flexible combination, do not enumerate one by one at this;

In the present embodiment, the unit of weight of each raw material of the described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache is a gram, also can be kilogram;

In the present embodiment, each raw material in the described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache is a conventional products, all can be in market and associated mechanisms buy and obtain;

In the present embodiment, equipment used in described pulverization process, the dried is conventional equipment, all can buy to obtain on market.

In the present embodiment, the overall process of described preparation method is carried out in medicine GMP workshop.

Embodiment 2

Present embodiment is the another kind of preferred version on embodiment 1 basis, is when the described dosage form that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache is decoct, the preparation method of employing.Disclosed content also should be as the content of present embodiment among the embodiment one.

The A raw material is handled

B. finished product preparation:

The a mixed processing

B decocts processing

Described raw material fine powder mixture is added entry, decoct processing, can obtain the described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache; The described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache is carried out getting product after packing is handled.

It can be conventional decocting method that described decoction is handled, preferred following decoction step:

A, described raw material fine powder mixture is added entry, carry out immersion treatment, obtain the raw material immersion; The ratio of weight and number of raw material fine powder mixture and water is 1:1 ~ 5, is preferably 1:5; The time of described immersion treatment is 10-50min, is preferably 30min;

B, described raw material immersion boiled with high heat after, reuse slow fire boiling 20 ~ 30 minutes, preferred 30 minutes; Refilter the raw material immersion that separates after decocting, obtain decocting liquid and medicinal residues for the first time for the first time;

C, add entry in the medicinal residues, obtain the medicinal residues mixed liquor in the described first time; Described first time, the ratio of weight and number of medicinal residues and water was 1:1 ~ 3, preferred 1:2;

D, described medicinal residues mixed liquor boiled with high heat after, reuse slow fire boiling 10 ~ 20 minutes, preferred 15 minutes; Refilter the medicinal residues mixed liquor that separates after decocting, obtain decocting liquid and medicinal residues for the second time for the second time;

E, general medicinal residues for the second time carry out the processing of marc extracting juice, and medicinal liquid obtains squeezing the juice;

F, merge described first time of decocting liquid, the decocting liquid and the medicinal liquid of squeezing the juice for the second time, can obtain the described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache.

Also can in the described Chinese medicine preparation decoct that cures mainly angina pectoris, trigeminal neuralgia, headache, add adjuvants such as glucose, make the extract oral liquid preparation of treatment angina pectoris, trigeminal neuralgia, sciatica.

Embodiment 3

Present embodiment is the another kind of preferred version on embodiment 1 basis, is when the described dosage form that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache is tablet, the preparation method of employing.Disclosed content also should be as the content of present embodiment among the embodiment one.

The A raw material is handled

B. finished product preparation:

The a mixed processing

The ratio of weight and number that described microcrystalline Cellulose accounts for described total mixture is 0.02～0.05:100; Be preferably 0.035:100;

The ratio of weight and number that described carboxymethyl starch sodium accounts for described total mixture is 0.1～1:100; Be preferably 0.6:100;

In the described dried, temperature is 38～40 ℃, is preferably 39 ℃;

The ratio of weight and number that described magnesium stearate accounts for described pressing mixt is 0.15～1:100, is preferably 0.5:100;

The Chinese medicinal tablet finished product of described treatment angina pectoris, trigeminal neuralgia, sciatica can be plain sheet; Can coated again processing back be coated tablet also, the coating of described coated tablet be sugar-coat or film-coat.

Embodiment 4

Present embodiment is the another kind of preferred version on embodiment 1 basis, is when the described dosage form that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache is pill, the preparation method of employing.Disclosed content also should be as the content of present embodiment among the embodiment one.

The described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache dosage form be pill, preparation process is as follows:

The A raw material is handled

B. finished product preparation:

The a mixed processing

B. with described raw material fine powder mixture and Mel mixing, obtain the pill mixture; The ratio of weight and number of described raw material fine powder mixture and described Mel is 10:2～7, is preferably 10:3;

C. described pill mixture is carried out mixing and handle, carry out again dried, cold preservation processing, dried, pill processing, promptly get the medicine pill finished product of described treatment angina pectoris, trigeminal neuralgia, sciatica; And will this described treatment angina pectoris, store behind the medicine pill finished product packing of trigeminal neuralgia, sciatica.

During described mixing was handled, temperature was 19～24 ℃, is preferably 21 ℃;

During described cold preservation was handled, temperature was 13～20 ℃, is preferably 15 ℃;

In the described dried, temperature is 35～37 ℃, is preferably 36 ℃;

Described pill is handled and is carried out according to relevant regulations.

In the present embodiment, described pill can be a honeyed pill, can be water-honeyed pill, the watered pill, concentrated pill, paste pill, wax pill etc. also, and its preparation method is those skilled in the art's a conventional means, does not give unnecessary details one by one at this.

Embodiment 5

Present embodiment is the another kind of preferred version on embodiment 1 basis, is when the described dosage form that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache is capsule, the preparation method of employing.Disclosed content also should be as the content of present embodiment among the embodiment one.

The A raw material is handled

B. finished product preparation:

The a mixed processing

B. with described raw mix and magnesium stearate mixing, obtain capsule 's content; The ratio of weight and number that described magnesium stearate accounts for described capsule 's content is 0.15～1:100, is preferably 0.5:100;

Again described capsule 's content is incapsulated in the housing, promptly get the Chinese medicinal capsule agent finished product for the treatment of angina pectoris, trigeminal neuralgia, sciatica.

Described capsule housing is the hard capsule housing, and the Chinese medicinal capsule agent finished product of described treatment angina pectoris, trigeminal neuralgia, sciatica is a hard capsule; Described capsule housing also can be the soft capsule shell body, and the Chinese medicinal capsule agent finished product of described treatment angina pectoris, trigeminal neuralgia, sciatica is for being soft capsule.

In the present embodiment, described pulverization process, the used equipment of dried are conventional equipment, all can buy to obtain on market.

Embodiment 6

Embodiment is the preferred version on embodiment 1 basis, and the quality of raw materials used (component) is identical with embodiment 1, and each raw materials in part by weight ratio is in the described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache:

Rhizoma Chuanxiong 2

Radix Saposhnikoviae 1

Rhizoma Et Radix Notopterygii 5

Radix Bupleuri 5

Herba Schizonepetae 1

In the present embodiment, the unit of weight of each raw material in the described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache is a gram, also can be kilogram.

When the described Chinese medicine preparation dosage form that cures mainly angina pectoris, trigeminal neuralgia, headache was powder, preparation method was referring to embodiment 1; When the described Chinese medicine preparation dosage form that cures mainly angina pectoris, trigeminal neuralgia, headache was decoct, preparation method was referring to embodiment 2; When the described Chinese medicine preparation dosage form that cures mainly angina pectoris, trigeminal neuralgia, headache was tablet, preparation method was referring to embodiment 3; When the described Chinese medicine preparation dosage form that cures mainly angina pectoris, trigeminal neuralgia, headache was pill, preparation method was referring to embodiment 4; When the described Chinese medicine preparation dosage form that cures mainly angina pectoris, trigeminal neuralgia, headache was capsule, preparation method was referring to embodiment 5.

Embodiment 7

Present embodiment is the preferred version on embodiment 1 basis, and the quality of raw materials used (component) is identical with embodiment 1, and each raw materials in part by weight ratio is in the described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache:

Rhizoma Chuanxiong 6

Radix Saposhnikoviae 3

Rhizoma Et Radix Notopterygii 3

Radix Bupleuri 3

Herba Schizonepetae 3;

Embodiment 8

Rhizoma Chuanxiong 11

Radix Saposhnikoviae 5

Rhizoma Et Radix Notopterygii 1

Radix Bupleuri 1

Herba Schizonepetae 5;

Embodiment 9

Rhizoma Chuanxiong 3

Radix Saposhnikoviae 4

Rhizoma Et Radix Notopterygii 3

Radix Bupleuri 2

Herba Schizonepetae 5;

Embodiment 10

Rhizoma Chuanxiong 2

Radix Saposhnikoviae 5

Rhizoma Et Radix Notopterygii 5

Radix Bupleuri 1

Herba Schizonepetae 1;

Embodiment 11

Rhizoma Chuanxiong 10

Radix Saposhnikoviae 2

Rhizoma Et Radix Notopterygii 1

Radix Bupleuri 4

Herba Schizonepetae 4;

Embodiment 11

Rhizoma Chuanxiong 9

Radix Saposhnikoviae 2

Rhizoma Et Radix Notopterygii 4

Radix Bupleuri 4

Herba Schizonepetae 2;

Below in conjunction with model case, the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache of the present invention is described further:

Angor case wholeheartedly

1 Wang, the man, 45 years old, existing 4 months of precordialgia, follow uncomfortable in chest, breathe hard, pain increases the weight of during physical exertion.Pained each a slice of oral at ordinary times nitre before the treatment, every day 2 times; Each 1 of Xin Kang, every day 2 times; Each 1 of nifedipine, every day 2 times, no positive effect; Have only nitroglycerine tablets to alleviate during pain, contain every day 2 ~ 3 times, each 1; After taking the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache of the present invention, consumption is each 9g, every day 2 times, obvious curative effects was promptly arranged after 4 days, and pain obviously alleviates, and cuts out nitroglycerine tablets behind the two weeks, pain is eliminated after 20 days, recovers substantially after 1 month.

2 Zhangs, the woman, 56 years old, precordialgia, back pain is radiated to shoulder, shows effect every day 3,4 times, is angina pectoris after diagnosing, and therapeutic scheme is pained each 2 of an oral nitre before, every day 2 times; Each 1 of diltiazem, every day 2 times; Train each half sheet of its happy gram, take the no positive effect in back every day 2 times, SUXIAO JIUXIN WAN does not have obvious curative effects yet.After taking the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, obvious curative effects was arranged in 7 days, afterwards every day potion, pain was eliminated in 25 days, basic rehabilitation in 40 days.

3 Zhao, woman, 47 years old.Angina pectoris has 5 years medical histories.Pain is 2,3 times weekly, and angry, worried, movable pain later on increases the weight of, and also has the premature beat symptom.Therapeutic scheme is that Western medicine such as oral nitre is pained, persantin, nifedipine, U.S. western rate are kept before; Taking medicine can relief of symptoms, but still has pain; After taking the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, obvious curative effects was promptly arranged in 5 days, also decrement thereupon of Western medicine simultaneously, basic rehabilitation in 40 days.

4 grandsons, man, 58 years old.Angina pectoris has 4 years medical histories, and every day 1 time or 3 pain are indefinite, the activity symptom that can aggravate the pain, and it is all not good enough to take multiple medicine effect.Closely half a year, pain increased the weight of, and need suck 4 ~ 5 nitroglycerin at every turn and keep.The expensive expense that is difficult to pay operation because of family's difficulty.After taking the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, 10 days take effect, and cooperate nitroglycerine tablets simultaneously, do not need to suck nitroglycerine tablets, basic rehabilitation in 70 days in 40 days later on.

5 Lee, the man, 60 years old, self-induction was uncomfortable in chest, breathe hard, precordialgia, back pain and omoplate osteodynia, frequent premature beat, symptom continues more than 2 months; Nearly two weeks symptom obviously increases the weight of, and need take a large amount of SUXIAO JIUXIN WAN during outbreak and come alleviating pain, be angina pectoris through hospital diagnosis, it is invalid to give the titration of coronary dilating medicine vein.After taking the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, 8 days take effect, basic rehabilitation in 50 days.

6 Zhao, woman, 58 years old.The twinge of pareordia paroxysmal easily shows effect when tired or excited, existing 2 years of medical history.Need suck nitroglycerin during pain and alleviate for the moment, electrocardiogram repeatedly check result is myocardial ischemia.In the recent period because the feelings of causing a disease of being busy with one's work increase the weight of, and the precordialgia outbreak is frequent, also follows bradycardia, pain unbearably, follow uncomfortable in chest, breathe hard; After taking the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, 8 days take effect, basic rehabilitation in 40 days.

7 Wang, man, 71 years old.The companion is uncomfortable in chest for precordialgia, existing 3 years of medical history, and pain increases the weight of and shows effect frequently closely over the past half year, shows effect every day 4 ~ 5 times, all continues 2,3 minutes at every turn, mostly occurs at night, generally sucks nitroglycerine tablets.The state of an illness increased the weight of to be the persistence precordialgia in nearly 1 month, especially with night for very, follow uncomfortable in chest, perspire, nervous, can't put down for sleeping inly, take the nitroglycerin DeGrain.After taking the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, 7 days take effect, painless substantially after 15 days, basic rehabilitation in 50 days.

8 weeks certain, the woman, 67 years old, uncomfortable in chest nervous, existing 1 year of chest pain was found blood supply insufficiency in the electrocardiogram, exciting, tired back sx; Take diltiazem, Radix Salviae Miltiorrhizae drop pill, propranolol DeGrain before.After taking the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, each 9 grams, every day 2 times, 7 days take effect, painless substantially after 15 days, basic rehabilitation in 40 days.

9 Hus, the woman, 67 years old, the WA pain of easily making up one's mind, pain is radiated to left arm and little finger of toe, and feeling of numbness is arranged, dizziness during outbreak, nervous, uncomfortable in chest, breathe hard, be diagnosed as angina pectoris.Take that Western medicine nitre is pained, diltiazem, persantin poor effect.After taking the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, 8 days take effect, basic rehabilitation in 40 days.

10 Feng, man, 57 years old.Existing 5 years of angina pectoris has the insomnia at ordinary times, palpitation and dizziness, and blurring of vision, gastrointestinal is uncomfortable.Chinese medicines such as Western medicine such as oral at ordinary times nitre is pained, Xin Kang, oryzanol, diazepam and XIANGSHA YANGWEI WAN, Radix Salviae Miltiorrhizae drop pill, SUXIAO JIUXIN WAN.Midwinter, season, angina pectoris took place frequently, and showed effect every day about 4 times, all continued 1 ~ 5 minute at every turn, radiated in the side arm left during pain, followed sensation of oppression over the chest with shortness of breath, cardiopalmus to have palpitation fatigue and weakness, aversion to cold and cold limbs; Electrocardiographic diagnosis is a myocardial ischemia.After taking the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, pain relief in 7 days, every day, outbreak was kept to 1 time, and symptom alleviates painless substantially sense in 20 days, basic rehabilitation in 70 days a little during pain.

The trigeminal neuralgia case

1 Lee, the man, 63 years old, existing 3 years of trigeminal neuralgia medical history, having a meal in the daily life opened one's mouth, speaks, washes one's face, brushed teeth etc. and also cause and have an intense pain, pain generally lasting 4 ~ 5 seconds, oral calorescence, sore place are looked like and are lancinated, and analgesic does not have positive effect.After taking the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, 15 days take effect, basic rehabilitation in 40 days.

2 Liu, the woman, 43 years old, suffering from the trigeminal neuralgia medical history has 2 years, dehisces to cause pain, and the burst absence of aura has an intense pain as electric shock, when serious with the facial muscle pain of twitching, sometimes rubescent with face, skin temperature symptom such as obviously increase, shed tears, the several seconds to 2 of at every turn showing effect minute stops suddenly.Therapeutic scheme is 6 of carbamazepines before, 3 of phenytoin Sodiums, poor effect.After taking the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, 10 days take effect, basic rehabilitation in 40 days.

3 Wang, the woman, 50 years old, existing 3 years of trigeminal neuralgia medical history was paroxysmal, the sample that lancinates has an intense pain, and continues 1 ~ 2 minute at every turn, shows effect every day 3 to 4 times, generally breaks out, and stops suddenly.After be developed to sx, continue 5 ~ 15 minutes at every turn, show effect every day 6 ~ 8 times, the washing one's face of daily life, brush teeth, size etc. all causes pain, take the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache after, 10 days take effect, basic rehabilitation in 40 days.

The headache case

1 Shandong, the man, 47 years old, existing 6 years of headache medical history, pain have when acute vomitted the sense of feeling sick, and influences appetite, and face has bitter color during pain, and the head blue veins exposes, and pushes head with hands.Seizure frequency is to show effect every day 1 time, and each about 1 hour, every day all takes dipyrone or brain is peaceful, and stomach has been caused very big stimulation.After taking the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, 10 days fruits that promptly take effect, basic rehabilitation in 45 days.

The facial paralysis case

1 Zhang, man, 35 years old, healthy and strong, pain, buccal numbness immediately behind the ear of prominent feel right side, the inconvenience of dehiscing, water flows out from bicker when drinking water, and the volume stricture of vagina disappears, facial hemiparalysis, slobbering, a sidelong glance can not be closed, disapperance of nasolabial sulcus, the gas leakage of the drum cheek, disease is first quarter moon, after use cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache, basic rehabilitation in 20 days.

The sciatica case

1 Feng, man, 50 years old, patient's sciatica 7 years.Whenever increase the weight of in cold and cool, fatigue, pain spot is in arm, thigh rear side, the shank outside.Cough, sneeze, hold one's breath, also occur firmly the time pain.Take Western medicine such as prednisone, Phenylbutazone, ibuprofen before; After taking the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, 10 days take effect, basic rehabilitation in 40 days.

The facial spasm case

1 Zhao, man, 37 years old.Existing 3 years of disease, the right side face spasm, double lip is held up, and is inferior surplus the frequency per minute about 20 during outbreak, outbreak too in bed, the right side palpebral fissure is smaller, and the companion sees insomnia; Take stable grade of Western medicine and all do not have obvious curative effects; After taking behind the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, each 9 grams, every day 2 times, 10 days take effect, basic rehabilitation in 40 days.

Claims

1. Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, it is characterized in that containing Rhizoma Chuanxiong, Radix Saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Bupleuri, Herba Schizonepetae in the raw material of the described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, described each raw material weight umber ratio that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache is:

Rhizoma Chuanxiong 2 ~ 11

Radix Saposhnikoviae 1 ~ 5

Rhizoma Et Radix Notopterygii 1 ~ 5

Radix Bupleuri 1 ~ 5

Herba Schizonepetae 1 ~ 5.

2. the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache according to claim 1 is characterized in that: described each raw material weight umber ratio of Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache is:

Rhizoma Chuanxiong 2

Radix Saposhnikoviae 1

Rhizoma Et Radix Notopterygii 5

Radix Bupleuri 5

Herba Schizonepetae 1.

3. the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache according to claim 1 is characterized in that: described each raw material weight umber ratio of Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache is:

Rhizoma Chuanxiong 6

Radix Saposhnikoviae 3

Rhizoma Et Radix Notopterygii 3

Radix Bupleuri 3

Herba Schizonepetae 3.

4. the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache according to claim 1 is characterized in that: described each raw material weight umber ratio of Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache is:

Rhizoma Chuanxiong 11

Radix Saposhnikoviae 5

Rhizoma Et Radix Notopterygii 1

Radix Bupleuri 1

Herba Schizonepetae 5.

5. the Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache according to claim 1 and 2 is characterized in that: the described dosage form that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache is powder, decoct, tablet, pill, capsule.

6. preparation method that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache, it is characterized in that: contain Rhizoma Chuanxiong, Radix Saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Bupleuri, Herba Schizonepetae in the raw material of the described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, described each raw material weight umber ratio that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache is:

Rhizoma Chuanxiong 2 ~ 11

Radix Saposhnikoviae 1 ~ 5

Rhizoma Et Radix Notopterygii 1 ~ 5

Radix Bupleuri 1 ~ 5

Herba Schizonepetae 1 ~ 5;

The A raw material is handled

B. finished product preparation:

7. preparation method that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache, it is characterized in that: contain Rhizoma Chuanxiong, Radix Saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Bupleuri, Herba Schizonepetae in the raw material of the described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, described each raw material weight umber ratio that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache is:

Rhizoma Chuanxiong 2 ~ 11

Radix Saposhnikoviae 1 ~ 5

Rhizoma Et Radix Notopterygii 1 ~ 5

Radix Bupleuri 1 ~ 5

Herba Schizonepetae 1 ~ 5;

The A raw material is handled

B. finished product preparation:

The a mixed processing

B decocts processing

8. preparation method that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache, it is characterized in that: contain Rhizoma Chuanxiong, Radix Saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Bupleuri, Herba Schizonepetae in the raw material of the described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, described each raw material weight umber ratio that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache is:

Rhizoma Chuanxiong 2 ~ 11

Radix Saposhnikoviae 1 ~ 5

Rhizoma Et Radix Notopterygii 1 ~ 5

Radix Bupleuri 1 ~ 5

Herba Schizonepetae 1 ~ 5;

The A raw material is handled

B. finished product preparation:

A. mixed processing

In the described dried, temperature is 38～40 ℃;

9. preparation method that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache, it is characterized in that: contain Rhizoma Chuanxiong, Radix Saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Bupleuri, Herba Schizonepetae in the raw material of the described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, described each raw material weight umber ratio that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache is:

Rhizoma Chuanxiong 2 ~ 11

Radix Saposhnikoviae 1 ~ 5

Rhizoma Et Radix Notopterygii 1 ~ 5

Radix Bupleuri 1 ~ 5

Herba Schizonepetae 1 ~ 5;

The A raw material is handled

B. finished product preparation:

A. mixed processing

During described mixing was handled, temperature was 19～24 ℃;

During described cold preservation was handled, temperature was 13～20 ℃;

In the described dried, temperature is 35～37 ℃.

10. preparation method that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache, it is characterized in that: contain Rhizoma Chuanxiong, Radix Saposhnikoviae, Rhizoma Et Radix Notopterygii, Radix Bupleuri, Herba Schizonepetae in the raw material of the described Chinese medicine preparation that cures mainly angina pectoris, trigeminal neuralgia, headache, described each raw material weight umber ratio that cures mainly the Chinese medicine preparation of angina pectoris, trigeminal neuralgia, headache is:

Rhizoma Chuanxiong 2 ~ 11

Radix Saposhnikoviae 1 ~ 5

Rhizoma Et Radix Notopterygii 1 ~ 5

Radix Bupleuri 1 ~ 5

Herba Schizonepetae 1 ~ 5;

The A raw material is handled

B. finished product preparation:

A. mixed processing