CN105891428B - A kind of full-automatic Bionic digestive system for monogastric animals - Google Patents
A kind of full-automatic Bionic digestive system for monogastric animals Download PDFInfo
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- CN105891428B CN105891428B CN201610426936.XA CN201610426936A CN105891428B CN 105891428 B CN105891428 B CN 105891428B CN 201610426936 A CN201610426936 A CN 201610426936A CN 105891428 B CN105891428 B CN 105891428B
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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Abstract
A kind of full-automatic Bionic digestive system for monogastric animals.A kind of full-automatic monogastric animal bionic digestion instrument, the upper left side of casing are equipped with digestion reaction room, and constant temperature air bath shaking table device is arranged in digestion reaction room；Automatic enzyme device is fixedly mounted in casing, and automatic enzyme device is connected with Bionic digestion device by woven hose；It buffers liquid circulating device and cleaning device is arranged on the lower section of casing, buffering liquid circulating device, cleaning device are connected respectively by woven hose with Bionic digestion device；Control circuit is arranged in casing, and pass through conducting wire and be connected with constant temperature air bath shaking table device, automatic enzyme device, buffering liquid circulating device, cleaning device, control circuit is connected with the industrial personal computer in casing, and industrial personal computer is connected with the display mounted on casing upper right side；Bionic digestion device is vertically installed above constant temperature air bath shaking table.Full-automatic monogastric animal bionic digestion instrument, it is simple in structure, it is easy to use, Bionic digestion reaction solution can be avoided to reveal, simulate the accuracy of digestion and reproducible, error is small.
Description
Technical field
The present invention relates to a kind of animal Bionic digestion devices, and bionical disappear is placed vertically more particularly, to a kind of simulation digester
Change indoor full-automatic Bionic digestive system for monogastric animals.
Background technology
In modern farming, the objective nutrient biological value for accurately evaluating feedstuff is to determine that Animal nutrition needs
Measure and optimize the primary decision-making basis of feed formula.In China, feedstuff species is various, renewal speed is faster,
If with the general survey of animal experiment method whole, predicting that the biological value of feed nutrient at least needs many decades, and result is only capable of
Obtain very limited static parameter.Therefore, the newer technology bottle of China's feed nutrient biological value parameter is restricted in order to break through
Neck, designs a kind of science, accurately and rapidly feed nutrient biological value testing tool is to be badly in need of, it can be modern supports
It grows industry and technical support is provided.
CN104034912A discloses a kind of full-automatic monogastric animal bionic digestion instrument, is shaken including casing, constant temperature air bath
Bed apparatus, Bionic digestion device, automatic enzyme device, buffering liquid circulating device, cleaning device, control circuit, the casing
Upper left side is equipped with digestion reaction room；The constant temperature air bath shaking table device and Bionic digestion device are arranged on the digestion reaction room
It is interior；The automatic enzyme device is fixedly mounted on the housing, and automatic enzyme device passes through defeated with the Bionic digestion device
Liquid pipe is connected；The buffering liquid circulating device and cleaning device are arranged on the lower section of the casing, buffering liquid circulating device, cleaning dress
It puts and is connected respectively by woven hose with the Bionic digestion device；The control circuit be arranged on casing below, and with cross conducting wire with
The constant temperature air bath shaking table device, automatic enzyme device, buffering liquid circulating device, cleaning device are connected.The full-automatic simple stomach
The simulation digester of animal Bionic digestion instrument is in horizontal（It is i.e. laterally disposed）In constant temperature air bath shaking table device, simulation digested
Journey easily causes the rubber stopper of Bionic digestion tube end outwards to take off due to feedstuff aerogenesis in digestion process in dialysis tubing
Fall, reaction solution leakage the problems such as, secondly, during Bionic digestion, treat that sample digestion is easily sticky causes on bag filter
Bag filter is blocked, and then influences the digestion effect of Feed Sample.
The content of the invention
The technical problem to be solved by the present invention is to：Overcome the deficiencies of the prior art and provide a kind of simple in structure, operation side
Just, Bionic digestion reaction solution can be avoided to reveal and simulate the complete of phenomena such as bag filter in digester is by cellulose degraded
Automatic Bionic digestive system for monogastric animals；Under in vitro conditions, the system can realistic simulation feed disappeared in animal gastrointestinal tract
The process changed, absorbed.
The technical solution adopted by the present invention to solve the technical problems is：A kind of full-automatic monogastric animal bionic digestion instrument,
Including casing, constant temperature air bath shaking table, Bionic digestion device, automatic enzyme device, buffering liquid circulating device, cleaning device, control
Circuit processed, the upper left side of the casing are equipped with digestion reaction room, and the constant temperature air bath shaking table device is arranged in digestion reaction room；
The automatic enzyme device is fixedly mounted in casing, and automatic enzyme device is connected with Bionic digestion device by woven hose；Institute
It states buffering liquid circulating device and cleaning device is arranged on the lower section of casing, buffering liquid circulating device, cleaning device pass through infusion respectively
Pipe is connected with Bionic digestion device；The control circuit is arranged in casing, and pass through conducting wire and constant temperature air bath shaking table device, from
It moves enzyme device, buffering liquid circulating device, cleaning device to be connected, the control circuit connects with the industrial personal computer in casing
It connects, the industrial personal computer is connected with the display mounted on casing upper right side；The Bionic digestion device is vertically installed at constant temperature sky
Above gas bath shaking table, i.e., the central axis of Bionic digestion device is vertical with constant temperature air bath shaking table.
Further, the Bionic digestion device includes fixing bracket, vertical simulation digester, glass pipe clip, stirring
Stick, motor and transmission device；The vertical simulation digester simulates digest tube and/or double glazing mould by the dialysis of several series connection
Paragastric canals forms；Clamping is mounted in the glass pipe clip the vertical simulation digester vertically, the stirring rod peace
In vertical simulation digest tube, top is detachably connected with transmission device；The transmission device is with being mounted on fixing bracket
The motor electrical connection on top；The glass pipe clip is fixedly mounted in the middle part of fixing bracket.
Further, the double glazing simulate digest tube by vertical glass tube, be set in the in vivo glass inner tube of hollow tube
It is formed with enzyme pipe, the vertical glass tube is a hollow tube, and the hollow tube upper and lower side is respectively provided with a ground, in ground
It is plugged with sealing-plug；Hollow tube side wall lower ends and upper end are respectively equipped with the second input pipe and the second efferent duct；The enzyme pipe is worn
It crosses hollow tube side wall and extends in glass inner tube, hollow tube inner space is separated into outer cavity volume and content by glass inner tube
Chamber.The second input pipe on double glazing simulation digest tube is heat preservation constant temperature water input, and the second efferent duct is permanent for heat preservation
Warm water delivery outlet, adjacent two double glazings are simulated in digest tubes, the constant temperature of forward double glazing simulation digest tube
Water input is connected with the constant temperature water output of another double glazing simulation digest tube by delivery hose, all double-deck glass
Glass simulation digest tube is sequentially connected in series by the delivery hose；Constant temperature water output near preceding double glazing simulation digest tube,
The constant temperature water input of double glazing simulation digest tube after is connected respectively by water-supply-pipe with the circulating water device.Institute
The vertical enzyme pipe in glass tube upper end is stated as digestive juice input port or buffer solution input port；Each described double glazing simulation digestion
The digestive juice input port of pipe is connected with the automatic enzyme device by hose, and buffer solution input port connects with buffering liquid circulating device
It connects.
Further, the transmission device includes connecting bushing and heightens drive link, and it is defeated that the connecting bushing is set in motor
On shaft, synchronously rotate with motor；The bottom for heightening drive link is connected with stirring rod, and top is socketed solid by screw rod
It is scheduled in the sliding slot below connecting bushing, enables to heighten drive link and moved up and down in connecting bushing；It is described to heighten on drive link
Equipped with locking nut, for heightening the locking degree between drive link and stirring rod.
Further, the drive link of heightening includes the body of rod and clamping jaw, and one end of the body of rod is fixedly connected with clamping jaw, close
The body of rod outer wall of clamping jaw is equipped with external screw thread, the internal thread phase of locking nut of the external screw thread with being used to adjust clamping jaw locking degree
Match somebody with somebody, one end away from clamping jaw at least offers 2 for installing the mounting hole of screw rod；Groove is additionally provided in the middle part of the body of rod.
Further, the fixing bracket by bottom plate, lower frame plate, backboard, side plate and gripper shoe groups into the bottom plate and undercarriage
Plate is fixedly connected；The lower frame plate is molded by one piece of sheet metal bent, the risers including a horizontal fixed plate and two pieces of settings, and two
Riser is located at below horizontal fixed plate, and with the left and right ends integrally connected of horizontal fixed plate；The lower end of riser is folded upward at
Into fixed block, mounting hole is equipped with location hole；It offers to fix the first of vertical glass pipe clip on horizontal fixed plate
Through hole, the backboard, side plate are fixed on the back upper place of lower frame plate, and the top of the backboard and side plate is fixedly connected with support plate,
Motor fixing threaded hole and motor shaft perforation are additionally provided in the support plate.
Further, the backboard, side plate and support plate are equipped with venthole, are additionally provided in the backboard and/or support plate
Pipeline is perforated.
Further, U-shaped card slot and mounting hole are offered on the bottom plate.
Further, the glass pipe clip is made of first clamping plate, second clamping plate and lock, the first clamping plate and
The end face that second splint contacts with each other is equipped with several clamp grooves for being used to place vertical glass tube, is also set in the clamp groove
There is the cushion course that shape is adapted with clamp groove.The first clamping plate is equipped with the second through hole, the first clamping plate and second
The middle part of clamping plate side be equipped with connection mounting hole, it is described lock by through connection mounting hole screw be fixed on first clamping plate and
The side of second clamping plate, for fixed first clamping plate and the second clamping plate of being buckled.
Further, the dialysis simulation digest tube includes vertical glass tube and dialysis tubing, and dialysis tubing is placed on the vertical glass
In glass pipe；The vertical glass tube is a hollow tube, and the hollow tube upper and lower side is respectively provided with a ground, side bottom and
Upper end is respectively equipped with the first input pipe and the first efferent duct；The both ends of dialysis tubing are respectively at two grounds of the vertical glass tube
It stretches out and turns up, the dialysis tube end being exposed on the outside of ground that turns up is tied up by rubber item to be fixed on ground, above and below hollow tube
It ties up the ground after dialysis tube end and is plugged with silica gel plug and solid silica gel plug at least one woven hose, the band respectively in end
There is the groove for being offered in the middle part of the silica gel plug of at least one woven hose and placing transmission device.First on dialysis simulation digest tube is defeated
Enter pipe for buffer solution input port, the first efferent duct is buffer solution delivery outlet, and adjacent two dialysis are simulated in digest tubes, forward
The buffer solution input port of one dialysis simulation digest tube and the buffer solution delivery outlet of another dialysis simulation digest tube pass through infusion
Hose is connected, and all dialysis simulation digest tube is sequentially connected in series by the infusion tube；Near preceding dialysis simulation digest tube
The buffer solution input port that buffer solution delivery outlet, the dialysis after simulate digest tube is followed respectively by woven hose and the buffer solution
Loop device is connected.The middle part of the woven hose is equipped with check valve, and the end of woven hose is equipped with quick coupling, and the quick coupling is
The digestive juice input port；The digestive juice input port of each dialysis simulation digest tube passes through with the automatic enzyme device
Hose is connected.
Further, the transmission device includes magnetic core, magnetic core fixed seat and connecting shaft；It is equipped on the outside of the magnetic core fixed seat
Magnetic loop cover；The magnetic core is connected by bearing with magnetic core fixed seat；The bottom of the magnetic core is connected with groove gap；It is described
The upper end of connecting shaft is set on the outside of magnetic core, and the hollow top of bottom and stirring rod is clamped.
Further, the transmission device includes outer magnetic ring set, outer magnetic ring, isolation cover, internal magnetic ring and internal magnetic ring pitman；Institute
Outer magnetic ring set is stated to be fixedly connected with output shaft, the upper seal bootr of motor；The outer magnetic ring, which is nested, to be located in outer magnetic ring；The interior magnetic
Isolation cover is equipped between ring and outer magnetic ring；The internal magnetic ring is mounted in isolation cover；One end of the internal magnetic ring pitman is caught in
In internal magnetic ring, the other end is inserted through lower seal bootr and silica gel plug, is connected with the top of stirring rod.
Further, the middle part of the digestion reaction room is equipped with one piece of partition plate, and wind-tunnel is equipped among partition plate；The partition plate is by institute
It states digestion reaction room and is divided into first half and latter half, the first half is connected with latter half by the wind-tunnel；
Baffle is further respectively had at left and right sides of the first half, baffle is equipped with multiple air holes；Positioned at the left side of first half
Baffle and casing outer wall enclosed space are connected with the latter half, in the baffle and casing on the right side of first half
Between plate enclosed space be connected with the latter half；The constant temperature air bath shaking table includes shaking table, electric fan, electric heater,
The shaking table is mounted in the first half, and the electric fan is mounted at the wind-tunnel, and the electric heater is mounted on institute
It states in latter half；The Bionic digestion device is fixedly mounted on the top of the shaking table.
Further, the shaking table includes shaking table driving motor, long axis, short axle, fixed plate, pallet fixed plate, shaking table driving
Motor, long axis and short axle are mounted on the different position of fixed plate；Long axis and short axle both pass through fixed plate, one end installation of long axis
There is the first belt pulley, the other end is connected with pallet fixed plate, and one end of short axle is connected with pallet fixed plate；Shaking table driving motor
Fixing end is mounted in fixed plate, and round end is connected with the second belt pulley；First belt pulley and the second belt pulley pass through skin
Band connection is together.
Further, the long axis and short axle are eccentric shaft；The quantity of the long axis is one, and the quantity of short axle is two
It is a；Long axis and two short axles are mounted in the shaped formation of equilateral triangle in fixed plate, i.e. long axis axle center and two short axle axle center
The triangle that 3 lines are formed is equilateral triangle；The fixed plate is equipped with to install with long axis, short axle corresponding section
First mounting hole of long axis and short axle, long axis and short axle are mounted on through the first mounting hole in fixed plate by screw；The length
Bearing is mounted on axis, short axle；The fixed plate is equipped with to install the second mounting hole of shaking table driving motor.
Further, the automatic enzyme device includes refrigerating box, peristaltic pump, refrigeration mechanism, and one is equipped in the refrigerating box
A heat exchanger, a rack for test tube and multiple Sheng enzyme pipes, the heat exchanger and rack for test tube are fixedly mounted in the refrigerating box；It is described
Enzyme pipe is contained to be placed on the rack for test tube；The heat exchanger is connected with the refrigeration mechanism by refrigerant pipe；The Sheng enzyme pipe
Upper end for open end, each lower end for containing enzyme pipe is connected with a defeated enzyme hose；The defeated enzyme hose passes through the refrigeration
The tank wall of case is connected by the peristaltic pump with the digestive juice input port of the simulation digester.
Further, the peristaltic pump is equipped with motor, pump seat, drive end bearing bracket, rear end cap, connecting rod, roller beam, fastener；It is described
Motor is fixedly mounted on the pump seat, and the front end of the pump seat is fixedly connected with the rear end of the rear end cap, the rear end cap
Front end be fixedly connected with the rear end of the drive end bearing bracket by the connecting rod；The roller beam is equipped with more rollers, roller beam
Between the drive end bearing bracket and rear end cap, the rear end of roller beam is connected with the motor, and by motor drive roller beam around
The central axis of roller beam；The fastener across in the top of the roller beam, with the connecting rod fix by the lower end of fastener
Connection, fastener is interior to be equipped with through hole, and the defeated enzyme hose passes through the digestive juice input port company of the through hole and the simulation digester
It connects.
A kind of advantageous effect of full-automatic Bionic digestive system for monogastric animals of the present invention：
1）Bionic digestive system for monogastric animals of the present invention and based on the system simulation nonruminant digestion method realize
The process that simulation feed is digested in animal gastrointestinal tract, absorbs under in vitro conditions, entire simulation process are controlled automatically by computer
System is completed, can be unattended, eliminates interference from human factor, and reliability is high, and simulation verisimilitude is high, and simulation repeatability is good.This hair
Bright system structure is simple, and the method for the present invention is easy to operate, especially suitable for the monogastric animal feeds nutrient biology such as pig, chicken, duck
The quick measure of potency.
2）By injecting the different alimentary canal sections such as Stomach duodenum, jejunum, ileum, large intestine, small intestine into dialysis tubing
Digestive juice and it is corresponding change the buffer solution being passed through in vertical glass tube, alternatively, by injecting such as stomach, ten to glass inner tube
The digestive juice and buffer solution of the difference alimentary canal section such as two duodenum 12, jejunum, ileum, large intestine, small intestine, and lead in vertical glass tube
Enter the water of constant temperature, driven by the rotation of constant temperature air bath shaking table and motor under the collective effect that stirring rod is stirred, the present invention
The situation that conditions in vitro Imitating feed is digested and absorbs in each section of animal intestines and stomach alimentary canal is may be implemented in, such as is realized pair
Nonruminant stomach, small intestine and big intestinal digestion, the simulation of absorption process.
3）Present system and method not only can be to the stomach of nonruminant, small intestine and large intestine digestion, absorption process point
It is not simulated individually, digestion, absorption process progress continuous analog that can also be to the stomach of nonruminant, small intestine and large intestine, this
The continuous continual analog form of kind can avoid occurring residue problem occur in chyme transfer.
4）It is sequentially connected in series between each vertical input pipe for simulating digester, efferent duct in present system, this series connection
Mode ensure that the electrochemical conditions in all simulation digesters are consistent, so as to reduce simulation error, improve simulation precision.
5）Since the Bionic digestion device in present system is vertically installed above constant temperature air bath shaking table, vertical simulation
The gas that liquid, only vertical glass tube or the interior residual of glass inner tube is not present in the upper end of digester and digestion reaction generates,
Since gas is weaker to the active force of silica gel plug, and there is the gravity acted on downwards in silica gel plug/sealing-plug, therefore during use,
The gas that simulation digestion generates is difficult to come off silica gel plug/sealing-plug out of vertical glass tube end ground, can effectively avoid
The glass tube of traverse causes the rubber stopper at glass tube both ends due in simulating digestion process because digestion reaction aerogenesis in the prior art
Come off, reaction solution leakage the phenomenon that, improve the Stability and veracity of Bionic digestion；
6）Since the dialysis tubing in present system with the position that is in contact of vertical glass tube is tied up and used with rubber item
Turned welt rubber stopper stoppers, and therefore, the container for the splendid attire liquid that dialysis tubing and glass tube respectively constitute is independent of each other, separates
, buffer solution is respectively at from the digestion product generated in glass tube, dialysis tubing the two different containers, the object between them
Mass transter must be carried out by the molecular sieve on dialysis tubing, so, present system can to avoid because dialysis tubing it is poorly sealed
And the phenomenon that occurring directly to carry out mass exchange between buffer solution and digestion product, ensure that simulation animal gastrointestinal tract accuracy with
Verisimilitude.Also, dialysis tubing, dialysis tubing can not be returned to after flowing into glass tube via the molecular sieve on dialysis tubing due to digestion product
Other digestion reactions are can proceed with, therefore, this independent design of two containers of dialysis tubing and glass tube, which can be reduced effectively, to disappear
Change inhibition of the product to the digested reaction of dialysis tubing, accurately distinguish out digestion substance and undigested material, be conducive to move simulation
The digestion process of object gastrointestinal tract more approaches virtual condition.
7）When using present system, each input pipe for simulating digester, efferent duct are located at lower section, top respectively, this
The placement design of sample not only improves the cycling of buffer solution, but be conducive to remain buffer solution in a glass tube after digestion can be with
Thoroughly emptied.
8）In the present invention, by controlling the temperature and flow velocity of buffer solution, the saturating of simulation digester can be accurately controlled indirectly
The temperature in pipe is analysed, so that the temperature variations amplitude of Bionic digestion process is maintained in 0.4 DEG C, closer to the change of animal heat
Different scope, simulation effect are good.
Description of the drawings
Fig. 1-illustrate for a kind of stereochemical structure of full-automatic Bionic digestive system for monogastric animals in embodiment 1；
Fig. 2-it is a kind of rearview of full-automatic Bionic digestive system for monogastric animals in embodiment 1；
Fig. 3-for the enlarged diagram at A in Fig. 1；
Fig. 4-for the sectional view in C-C sections in Fig. 3；
Fig. 5-it is the sectional view that double glazing simulates dialysis tubing in Fig. 3；
Fig. 6-it is the dimensional structure diagram that drive link is heightened in Fig. 3；
Fig. 7-it is support bracket fastened dimensional structure diagram in Fig. 3；
Fig. 8-for the dimensional structure diagram of glass tube test tube clamp in Fig. 3；
Fig. 9-for the enlarged diagram of constant temperature air bath shaking table at B in Fig. 2；
Figure 10-for the front view of Bionic digestion device in embodiment 2；
Figure 11-for the sectional view in D-D sections in Figure 10；
Figure 12-for the enlarged diagram at E in Figure 11；
Figure 13-for the front view of Bionic digestion device in embodiment 3；
Figure 14-for the sectional view in F-F sections in Figure 13；
Figure 15-for the enlarged diagram at G in Figure 14.
Specific embodiment
The invention will be further described with reference to the accompanying drawings and embodiments.
Embodiment 1
With reference to Fig. 1 ~ 5, a kind of full-automatic monogastric animal bionic digestion instrument of the present embodiment, including casing 2, constant temperature air bath
Shaking table 6, Bionic digestion device 4, automatic enzyme device, buffering liquid circulating device, cleaning device, control circuit 5, the casing 2
Upper left side be equipped with digestion reaction room 3,6 device of constant temperature air bath shaking table be arranged on digestion reaction room 3 in；It is described automatic enzyme
Device is fixedly mounted in casing 2, and automatic enzyme device is connected with Bionic digestion device 4 by woven hose 58；The buffer solution
Circulator and cleaning device are arranged on the lower section of casing 2, and buffering liquid circulating device, cleaning device are respectively by woven hose 58 with imitating
Raw slaking apparatus 4 is connected；The control circuit 5 is arranged in casing 2, and passes through conducting wire and 6 device of constant temperature air bath shaking table, automatic
Enzyme device, buffering liquid circulating device, cleaning device are connected, and the control circuit 5 is connected with the industrial personal computer in casing,
The industrial personal computer is connected with the display 1 mounted on 2 upper right side of casing；The Bionic digestion device 4 is vertically installed at constant temperature sky
6 top of gas bath shaking table, i.e., the central axis of Bionic digestion device 4 is vertical with constant temperature air bath shaking table 6.
With reference to Fig. 3, the Bionic digestion device 4 includes fixing bracket, vertical simulation digester, glass pipe clip 7, stirs
Mix stick 11, motor 15 and transmission device；The vertical simulation digester simulates digestion by the double glazing of 2 groups, every group 5 series connection
Pipe forms；Clamping is mounted in the glass pipe clip 7 the vertical simulation digester vertically, and the stirring rod 11 is mounted on
In vertical simulation digest tube, top is detachably connected with transmission device；The transmission device is with being mounted on fixing bracket top
Motor 15 be electrically connected；The glass pipe clip 7 is fixedly mounted in the middle part of fixing bracket.
With reference to Fig. 5, the double glazing simulate digest tube by vertical glass tube 8, be set in the in vivo glass of hollow tube
Pipe 26 and enzyme pipe 9 form, and the vertical glass tube 8 is a hollow tube, and the hollow tube upper and lower side is respectively provided with a ground,
Sealing-plug 21 is plugged in ground；Hollow tube side wall lower ends and upper end are respectively equipped with the second input pipe 27 and the second efferent duct 10；
The enzyme pipe 9 is through hollow tube side wall and extending in glass inner tube 26, and glass inner tube 26 is by hollow tube inner space
It is separated into outer cavity volume and content cavity.
With reference to Fig. 6, the transmission device includes connecting bushing 14 and heightens drive link 13, and the connecting bushing 14 is set in
On 15 output shaft of motor, synchronously rotate with motor 15；The bottom for heightening drive link 13 is connected with stirring rod 11, top
It is fixed by socket by screw rod 22 in the sliding slot 23 below connecting bushing 14, enables to heighten drive link 13 on connecting bushing 14 is interior
Lower movement；The drive link 13 of heightening is equipped with locking nut 12, for heightening between drive link 13 and stirring rod 11
Locking degree.
The drive link 13 of heightening includes the body of rod and clamping jaw 25, and one end of the body of rod is fixedly connected with clamping jaw 25, close
The body of rod outer wall of clamping jaw 25 is equipped with external screw thread 28, locking nut 12 of the external screw thread 28 with being used to adjust the locking degree of clamping jaw 25
Internal thread matches, and one end away from clamping jaw 25 at least offers 2 for installing the mounting hole 30 of screw rod 22；In the body of rod
Portion is additionally provided with groove 29.
With reference to Fig. 7, the fixing bracket is made of bottom plate 20, lower frame plate 19, backboard 18, side plate 17 and support plate 16, institute
Bottom plate 20 is stated to be fixedly connected with lower frame plate 19；The lower frame plate 19 is molded by one piece of sheet metal bent, including a horizontal fixed plate
With two pieces setting riser, two risers be located at horizontal fixed plate lower section, and with the left and right ends integrally connected of horizontal fixed plate；It is vertical
The lower end of plate is folded upward at into fixed block, and mounting hole 30 is equipped with location hole 37；It offers to fix on horizontal fixed plate
The first through hole 34 of 8 geometrical clamp 7 of vertical glass tube, the backboard 18, side plate 17 are fixed on the back upper place of lower frame plate 19, the back of the body
The top of plate 18 and side plate 17 is fixedly connected with support plate 16, and motor fixing threaded hole 32 and motor are additionally provided in the support plate 16
Axis perforation 31.
The backboard 18, side plate 17 and support plate 16 are equipped with venthole 24, are gone back on the backboard 18 and/or support plate 16
Equipped with pipeline perforation 33.
U-shaped card slot 36 and mounting hole 35 are offered on the bottom plate 20.
With reference to Fig. 8, the glass pipe clip 7 is made of first clamping plate 38, second clamping plate 41 and lock 42, and described first
The end face that clamping plate 38 and second clamping plate 41 contact with each other is equipped with several clamp grooves 40 for being used to place vertical glass tube 8, institute
It states and the cushion course that shape is adapted with clamp groove 40 is additionally provided in clamp groove 40.It is logical that the first clamping plate 38 is equipped with second
Hole, the middle part of 41 side of the first clamping plate 38 and second clamping plate are equipped with connection mounting hole 43, and the lock 42 passes through the company of passing through
The screw for connecing mounting hole 43 is fixed on the side of first clamping plate 38 and second clamping plate 41, for fixed first clamping plate 38 and of being buckled
Second splint 41.
The middle part of the digestion reaction room 3 is equipped with one piece of partition plate, and wind-tunnel is equipped among partition plate；The partition plate is by the digestion
Reative cell 3 is divided into first half and latter half, and the first half is connected with latter half by the wind-tunnel；Before described
Baffle is further respectively had at left and right sides of half part, baffle is equipped with multiple air holes；Positioned at the left side of first half baffle and
2 outer wall enclosed space of casing is connected with the latter half, positioned at the baffle on the right side of first half and the intermediate plate of casing 2
Enclosed space is connected with the latter half；The constant temperature air bath shaking table 6 includes shaking table, electric fan, electric heater, described
Shaking table is mounted in the first half, and the electric fan is mounted at the wind-tunnel, and the electric heater installation is in the rear
In half part；The Bionic digestion device 4 is fixedly mounted on the top of the shaking table.
With reference to Fig. 9, the shaking table includes shaking table driving motor 51, long axis 48, short axle 46, fixed plate 49, pallet fixed plate
44, shaking table driving motor 51, long axis 48 and short axle 46 are mounted on the different position of fixed plate 49；Long axis 48 and short axle 46 are worn
Fixed plate 49 is crossed, one end of long axis 48 is equipped with the first belt pulley（It does not indicate）, the other end is connected with pallet fixed plate 44, short axle
46 one end is connected with pallet fixed plate 44；The fixing end of shaking table driving motor 51 is mounted in fixed plate 49, round end connection
There is the second belt pulley 53；First belt pulley（It does not indicate）It is linked together with the second belt pulley 53 by belt 52.
The long axis 48 and short axle 46 are eccentric shaft；The quantity of the long axis 48 is one, and the quantity of short axle 46 is two
It is a；Long axis 48 and two short axles 46 are mounted in the shaped formation of equilateral triangle in fixed plate 49, i.e. 48 axle center of long axis and two
The triangle that 3,46 axle center of short axle line is formed is equilateral triangle；The fixed plate 49 is corresponding with long axis 48, short axle 46
Place is equipped with to install long axis 48 and the first mounting hole 45 of short axle 46, and long axis 48 and short axle 46 pass through first by screw 47
Mounting hole 45 is mounted in fixed plate 49；Bearing 54 is mounted on the long axis 48, short axle 46；Fixed plate 49 is equipped with and is used for
Second mounting hole 50 of shaking table driving motor 51 is installed.
The automatic enzyme device includes refrigerating box, peristaltic pump, refrigeration mechanism, sets that there are one heat exchange in the refrigerating box
Device, a rack for test tube and multiple Sheng enzyme pipes, the heat exchanger and rack for test tube are fixedly mounted in the refrigerating box；The Sheng enzyme pipe
It is placed on the rack for test tube；The heat exchanger is connected with the refrigeration mechanism by refrigerant pipe；The upper end for containing enzyme pipe
For open end, each lower end for containing enzyme pipe is connected with a defeated enzyme hose；The defeated enzyme hose passes through the case of the refrigerating box
Wall is connected by the peristaltic pump with the digestive juice input port of the simulation digester.
The peristaltic pump is equipped with motor, pump seat, drive end bearing bracket, rear end cap, connecting rod, roller beam, fastener；The motor is fixed
On the pump seat, the front end of the pump seat is fixedly connected with the rear end of the rear end cap, the front end of the rear end cap with
The rear end of the drive end bearing bracket is fixedly connected by the connecting rod；The roller beam is equipped with more rollers, and roller beam is mounted on institute
It states between drive end bearing bracket and rear end cap, the rear end of roller beam is connected with the motor, and drives roller beam around roller beam by motor
Central axis；The fastener is across in the top of the roller beam, and the lower end of fastener is fixedly connected with the connecting rod, fastener
Interior to be equipped with through hole, the defeated enzyme hose is connected through the through hole with the digestive juice input port of the simulation digester.
Embodiment 2
Referring to Figures 1 and 2 and Figure 10 ~ 12, a kind of full-automatic nonruminant gastrointestinal tract Bionic digestion system of the present embodiment,
Compared with the full-automatic nonruminant gastrointestinal tract Bionic digestion system described in embodiment 1, there are following differences：
The vertical simulation digester is made of the dialysis simulation digest tube of 2 groups, every group 5 series connection.
With reference to Figure 11, the dialysis simulation digest tube includes vertical glass tube 8 and dialysis tubing 60, and dialysis tubing 60 is placed on this
In vertical glass tube 8；The vertical glass tube 8 is a hollow tube, and the hollow tube upper and lower side is respectively provided with a ground, side
Face bottom and upper end are respectively equipped with the first input pipe 56 and the first efferent duct 57；The both ends of dialysis tubing 60 are respectively from the vertical glass
It stretches out and turns up at two grounds of pipe 8,60 end of dialysis tubing being exposed on the outside of ground of turning up is tied up by rubber item is fixed on mill
On mouth, hollow tube upper and lower side ties up the ground behind 60 end of dialysis tubing and is plugged with the silica gel at least one woven hose 58 respectively
Plug 59 and solid silica gel plug 55, the silica gel plug middle part at least one woven hose 58, which offers, places the recessed of transmission device
Slot 29.The first input pipe 56 on dialysis simulation digest tube is buffer solution input port, and the first efferent duct 57 is buffer solution delivery outlet,
In two adjacent dialysis simulation digest tubes, buffer solution input port and another dialysis of forward dialysis simulation digest tube
Simulation digest tube buffer solution delivery outlet be connected by infusion tube, all dialysis simulate digest tube by the infusion tube according to
Secondary series connection；Buffer solution delivery outlet near preceding dialysis simulation digest tube, the buffer solution of the dialysis simulation digest tube after are defeated
Entrance is connected respectively by woven hose 58 with the buffering liquid circulating device.The middle part of the woven hose 58 is equipped with check valve, defeated
The end of liquid pipe 58 is equipped with quick coupling, and the quick coupling is the digestive juice input port.Each described dialysis simulation disappears
The digestive juice input port for changing pipe is connected with the automatic enzyme device by hose.
With reference to Figure 12, the transmission device includes magnetic core 68,68 fixed seat 65 of magnetic core and connecting shaft 61；The magnetic core 68 is solid
65 outside of reservation is equipped with magnetic loop cover 66；The magnetic core 68 is connected by bearing 67 with 68 fixed seat 65 of magnetic core；The magnetic core 68
Bottom is connected with 29 clearance fit of groove；The upper end of the connecting shaft 61 is set in 68 outside of magnetic core, bottom and stirring rod 11
Hollow top clamping.
The junction of the transmission device and the silica gel plug 59 with woven hose is equipped with the first sealing ring 62.
Motor cover 64 is arranged on the motor, the bottom of the motor cover 64 is connected with motor fixing seat 64, the electricity
Machine fixed seat 64 is made of upper seal bootr 64-1 and lower seal bootr 64-2.
Embodiment 3
Reference Fig. 1, Fig. 2, Figure 13 ~ 15, a kind of full-automatic nonruminant gastrointestinal tract Bionic digestion system of the present embodiment, with
Full-automatic nonruminant gastrointestinal tract Bionic digestion system described in embodiment 2 is compared, and there are following differences：
With reference to Figure 13 ~ 15, the transmission device includes outer magnetic ring set 71, outer magnetic ring 72, isolation cover 73, internal magnetic ring 74 and interior
Magnet ring pitman 76；The outer magnetic ring set 71 is fixedly connected with output shaft, the upper seal bootr 64-1 of motor 15；The outer magnetic ring set
71 are embedded in outer magnetic ring 72；Isolation cover 73 is equipped between the internal magnetic ring 74 and outer magnetic ring 72；The internal magnetic ring 74 is mounted on
In isolation cover 73；One end of the internal magnetic ring pitman 76 is caught in internal magnetic ring 74, and the other end is inserted through lower seal bootr 64-
2 and silica gel plug, it is connected with the top of stirring rod 11.
The Bionic digestion device further include the pumping peristaltic pump 69 that is connected with the first input pipe 56 and with the first efferent duct
The pumping peristaltic pump 70 of 57 connections.
The second sealing ring 75 is equipped between the upper seal bootr 64-1 and lower seal bootr 64-2, is bolted to connection.
Embodiment 4
A kind of full-automatic nonruminant gastrointestinal tract Bionic digestion system of the present embodiment, it is full-automatic described in embodiment 1
Nonruminant gastrointestinal tract Bionic digestion system is compared, and there are following differences：
The double glazing simulation that the vertical simulation digester is simulated digest tube and 5 series connection by the dialysis of 5 series connection disappears
Change pipe composition.
Dialysis simulation digest tube is the same as described in embodiment 2.
A kind of full-automatic nonruminant gastrointestinal tract Bionic digestion system described in embodiment 2 and 3, operation principle：Pass through
The stirring action of stirring rod 11 in the concussion of constant temperature air bath shaking table 6 and dialysis simulation digest tube is simulation nonruminant stomach, small
Intestines, large intestine are to the digestion process of Feed Sample.
Its application method：
With the method phase of the Bionic digestive system for monogastric animals simulation nonruminant digestion described in 101482460 A of CN
Than there are following differences：
The concrete operations of 1-3 in preparation process are：Open constant temperature air bath shaking table 6, the dialysis on the first fixing bracket
Simulation digest tube starts to shake, meanwhile, start the motor 15 on dialysis simulation digest tube, the stirring rod dialysed in simulation digest tube
Feed Sample in 11 stirring dialysis tubings 60, strengthen mixing in follow-up Bionic digestion step between Feed Sample and digestive juice and
The adequacy of digestion reaction.
During Bionic digestion：Feed Sample is packed into dialysis tubing, stomach simulated digestive juice is injected by woven hose in dialysis tubing.So
Afterwards, there is the stomach buffer solution of a design temperature, in the pumping peristaltic pump and pump being connected with simulating input pipe, the efferent duct of digest tube
It under the action of inhaling peristaltic pump, is injected via input pipe in vertical glass tube, then flows out vertical glass tube via efferent duct, and pump
Send peristaltic pump power be less than pumping peristaltic pump power, make between the vertical glass tube of simulation digest tube and dialysis tubing formed compared with
Low negative pressure（Such as -0.01MPa ~ -0.04MPa）, and the liquid level of reaction solution does not generate fluctuation in bag filter, makes to treat in bag filter
The non-sticky error for adhering on dialysis tube wall, reducing simulation digestion process of the sample of digestion.Like this, the stomach buffering of certain volume
Liquid such circularly vertical glass tube of inflow and outflow in a setting time, at the same time, motor drives magnetic drives dress
The magnetic core put does cutting magnetic line movement with respect to magnetic core fixed seat, and then magnetic core rotates, and by connecting shaft stirring rod is driven to turn
It is dynamic, alternatively, motor drives outer magnetic ring set and outer magnetic ring to rotate, outer magnetic ring is made to generate rotating excitation field in isolation cover, magnetic in drive
Ring rotates, and the internal magnetic ring pitman being caught in internal magnetic ring drives stirring rod to rotate, and then realizes to the Feed Sample in bag filter
With being stirred for stomach simulated digestive juice, rotating speed >=100r/min of stirring rod, it is ensured that between stomach simulated digestive juice and Feed Sample
Sealing stirring is realized in vertical glass pipe, is sufficiently mixed, completes the simulation digestion process that stomach stage chyme is wriggled.In the setting
In time, with Feed Sample digestion reaction occurs in dialysis tubing for the stomach simulated digestive juice under stirring, and generation disappears
Change product by the molecular sieve outflow of dialysis tubing and carry out mass exchange with the stomach buffer solution in vertical glass tube, digestion product is molten
Enter in stomach buffer solution and cannot return in dialysis tubing that (digestion product generated is taken away by stomach buffer solution, so that is generated disappears
Change product and do not interfere with other reactions then carried out in dialysis tubing), indigested product has been left behind in dialysis tubing, then,
The stomach buffer solution dissolved with digestion product in vertical glass tube is all discharged, deionized water is by pumping peristaltic pump via input
Pipe is injected in vertical glass tube, and after through pumping peristaltic pump vertical glass tube is flowed out by efferent duct, like this, certain volume is gone
Ionized water circularly the vertical glass tube of inflow and outflow for several times, by remaining stomach buffer solution and dialysis in vertical glass tube
Remaining digestion product cleans up in pipe, so as to complete the simulation digestion process of stomach.
A kind of full-automatic nonruminant gastrointestinal tract Bionic digestion system described in embodiment 1, operation principle：Pass through constant temperature
The stirring action of stirring rod 11 in the concussion of air bath shaking table 6 and double glazing simulation digest tube is simulation nonruminant stomach, small
Intestines, large intestine are to the digestion process of Feed Sample.Dialysis in digestive juice reconvert to simulation digest tube of dialysing after having digested, simulation
The absorption process of nutrient.
Its application method：It is used to simulate nonruminant digestion with the Bionic digestive system for monogastric animals described in example 2 and 3
Method is compared, and there are following differences：
The concrete operations of 1-3 in preparation process are：Open constant temperature air bath shaking table 6, the bilayer on the first fixing bracket
Glass molds paragastric canals starts to shake, meanwhile, start the motor 15 on double glazing simulation digest tube, double glazing simulation digestion
Stirring rod 11 in pipe stirs the Feed Sample in glass inner tube 26, strengthens Feed Sample and digestion in follow-up Bionic digestion step
The adequacy of mixing and digestion reaction between liquid.
It treats after reaction, enzyme pipe 9 of the digestive juice under the action of pumping peristaltic pump 70 through lower end or is manually transferred to
Filtering in dialysis simulation digest tube makes the digestion product in dialysis tubing 60 carry out object with the stomach outside dialysis tubing 60/small intestine buffer solution
Mass transter, digestion product dissolve in stomach/small intestine buffer solution and cannot return in dialysis tubing 60 that (digestion product generated is delayed by stomach
Fliud flushing is taken away, so that the digestion product generated does not interfere with other reactions then carried out in dialysis tubing 60), in bag filter only
Indigested product is left, then, the stomach dissolved with the digestion product/small intestine buffer solution dialysed in simulation digest tube is all arranged
Go out, deionized water is injected via input pipe in vertical glass tube 8 by pumping peristaltic pump 69, and after through pumping peristaltic pump 70 by defeated
Outlet pipe flows out vertical glass tube 8, and like this, circularly the vertical glass tube 8 of inflow and outflow counts the deionized water of certain volume
It is secondary, remaining digestion product in remaining stomach buffer solution in vertical glass tube 8 and dialysis tubing 60 is cleaned up, so as to complete
Into the simulation digestion process of stomach/small intestine.
Claims (8)
1. a kind of full-automatic Bionic digestive system for monogastric animals, which is characterized in that including casing, constant temperature air bath shaking table, bionical
Slaking apparatus, automatic enzyme device, buffering liquid circulating device, cleaning device, control circuit, the upper left side of the casing, which is equipped with, to disappear
Change reative cell, the constant temperature air bath shaking table device is arranged in digestion reaction room；The automatic enzyme device is fixedly mounted on machine
In shell, automatic enzyme device is connected with Bionic digestion device by woven hose；The buffering liquid circulating device and cleaning device are set
In the lower section of casing, buffering liquid circulating device, cleaning device are connected respectively by woven hose with Bionic digestion device；The control
Circuit is arranged in casing, and is passed through conducting wire and constant temperature air bath shaking table device, automatic enzyme device, buffered liquid circulating device, is clear
Cleaning device is connected, and the control circuit is connected with the display mounted on casing upper right side；The Bionic digestion device is pacified vertically
Above constant temperature air bath shaking table；The Bionic digestion device, which includes fixing bracket, vertical simulation digester, glass tube, to be fixed
Folder, stirring rod, motor and transmission device；Dialysis simulation digest tube and double-deck glass of the vertical simulation digester by several series connection
Glass is simulated digest tube or is made of the double glazing simulation digest tube of several series connection；The vertical simulation digester clamps vertically
In the glass pipe clip, the stirring rod is mounted in vertical simulation digest tube, and top can with transmission device
Dismantling connection；The transmission device is electrically connected with the motor mounted on fixing bracket top；The glass pipe clip fixes peace
In the middle part of fixing bracket；The double glazing simulate digest tube by vertical glass tube, be set in the in vivo glass of hollow tube
Pipe and enzyme pipe composition, the vertical glass tube are a hollow tube, and the hollow tube upper and lower side is respectively provided with a ground, ground
Inside it is plugged with sealing-plug；Hollow tube side wall lower ends and upper end are respectively equipped with the second input pipe and the second efferent duct；The enzyme pipe
It through hollow tube side wall and extends in glass inner tube, hollow tube inner space is separated into outer cavity volume and interior by glass inner tube
Cavity volume.
2. full-automatic Bionic digestive system for monogastric animals as described in claim 1, which is characterized in that the transmission device includes connecting
Spindle covers and heightens drive link, and the connecting bushing is set on motor output shaft, synchronously rotates with motor；It is described to heighten biography
The bottom of lever is connected with stirring rod, and top is socketed by screw rod in the sliding slot being fixed below connecting bushing, makes to heighten biography
Lever can move up and down in connecting bushing；The drive link of heightening equipped with locking nut, for heighten drive link and
Locking degree between stirring rod.
3. full-automatic Bionic digestive system for monogastric animals as claimed in claim 2, which is characterized in that the drive link of heightening includes
The body of rod and clamping jaw, one end of the body of rod are fixedly connected with clamping jaw, and the body of rod outer wall close to clamping jaw is equipped with external screw thread, external screw thread
With matching for adjusting the internal thread of the locking nut of clamping jaw locking degree, one end away from clamping jaw at least offers 2 use
In the mounting hole of installation screw rod；Groove is additionally provided in the middle part of the body of rod.
4. full-automatic Bionic digestive system for monogastric animals as claimed in claim 1 or 2, which is characterized in that the fixing bracket by
Bottom plate, lower frame plate, backboard, side plate and gripper shoe groups are into the bottom plate is fixedly connected with lower frame plate；The lower frame plate is by one block of gold
Belong to plate bending and molding, including a horizontal fixed plate and two pieces of risers erect, two risers are located at below horizontal fixed plate, and and water
The left and right ends integrally connected of flat fixed plate；The lower end of riser is folded upward at into fixed block, and mounting hole is equipped with location hole；Water
Offer to fix the first through hole of vertical glass pipe clip in flat fixed plate, the backboard, side plate are fixed on lower frame plate
Back upper place, the top of the backboard and side plate is fixedly connected with support plate, and motor fixing threaded hole is additionally provided in the support plate
It perforates with motor shaft；The backboard, side plate and support plate are equipped with venthole, and pipe is additionally provided in the backboard and/or support plate
It perforates on road；U-shaped card slot and mounting hole are offered on the bottom plate.
5. full-automatic Bionic digestive system for monogastric animals as claimed in claim 1 or 2, which is characterized in that the glass tube is fixed
Folder is made of first clamping plate, second clamping plate and lock, and the end face that the first clamping plate and second clamping plate contact with each other is equipped with number
It is a for placing the clamp groove of vertical glass tube, the cushion that shape is adapted with clamp groove is additionally provided in the clamp groove
Layer.The first clamping plate is equipped with the second through hole, and the middle part of the first clamping plate and second clamping plate side is equipped with connection mounting hole,
The lock fixes the by being fixed on the side of first clamping plate and second clamping plate through the screw of connection mounting hole, for being buckled
One clamping plate and second clamping plate.
6. full-automatic Bionic digestive system for monogastric animals as claimed in claim 1 or 2, which is characterized in that the dialysis simulation disappears
Changing pipe includes vertical glass tube and dialysis tubing, and dialysis tubing is placed in the vertical glass tube；The vertical glass tube is hollow for one
Tube body, the hollow tube upper and lower side are respectively provided with a ground, and side bottom and upper end are respectively equipped with the first input pipe and first
Efferent duct；The both ends of dialysis tubing are stretched out at the two of the vertical glass tube grounds and are turned up respectively, turn up and are exposed on the outside of ground
Dialysis tube end tied up and be fixed on ground by rubber item, hollow tube upper and lower side ties up the ground difference after dialysis tube end
The silica gel plug at least one woven hose and solid silica gel plug are plugged with, in the middle part of the silica gel plug at least one woven hose
Offer the groove for placing transmission device.
7. full-automatic Bionic digestive system for monogastric animals as claimed in claim 1 or 2, which is characterized in that the transmission device bag
Include magnetic core, magnetic core fixed seat and connecting shaft；Magnetic loop cover is equipped on the outside of the magnetic core fixed seat；The magnetic core passes through bearing and magnetic core
Fixed seat connects；The bottom of the magnetic core is connected with groove gap；The upper end of the connecting shaft is set on the outside of magnetic core,
The hollow top of bottom and stirring rod is clamped.
8. full-automatic Bionic digestive system for monogastric animals as claimed in claim 1 or 2, which is characterized in that the transmission device bag
Include outer magnetic ring set, outer magnetic ring, isolation cover, internal magnetic ring and internal magnetic ring pitman；Output shaft, the upper envelope of the outer magnetic ring set and motor
Cover is closed to be fixedly connected；The outer magnetic ring, which is nested, to be located in outer magnetic ring；Isolation cover is equipped between the internal magnetic ring and outer magnetic ring；It is described
Internal magnetic ring is mounted in isolation cover；One end of the internal magnetic ring pitman is caught in internal magnetic ring, and the other end is inserted through lower envelope
Cover and silica gel plug are closed, is connected with the top of stirring rod.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610426936.XA CN105891428B (en) | 2016-06-16 | 2016-06-16 | A kind of full-automatic Bionic digestive system for monogastric animals |
| PCT/CN2017/087400 WO2017215498A1 (en) | 2016-06-16 | 2017-06-07 | Fully-automatic bionic digestive system for monogastric animals |
Applications Claiming Priority (1)
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| CN201610426936.XA CN105891428B (en) | 2016-06-16 | 2016-06-16 | A kind of full-automatic Bionic digestive system for monogastric animals |
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| CN105891428B (en) * | 2016-06-16 | 2018-05-25 | 湖南中本智能科技发展有限公司 | A kind of full-automatic Bionic digestive system for monogastric animals |
| CN110057964B (en) * | 2019-04-30 | 2021-11-16 | 中国农业科学院北京畜牧兽医研究所 | Program-controlled bionic pig digestion system and method for rapidly determining digestion energy value of pig feed by using same |
| CN110244007B (en) * | 2019-07-10 | 2022-03-08 | 湖南中本智能科技发展有限公司 | Bionic digestion simulation device and use method |
| CN113341059B (en) * | 2021-05-31 | 2023-09-22 | 中国农业科学院北京畜牧兽医研究所 | Bionic digestion method for growing pig stomach-small intestine-large intestine and application of bionic digestion method to estimation of effective value of feed |
| CN118109293B (en) * | 2024-03-13 | 2024-08-27 | 江南大学 | High-flux small intestine organ chip bionic system |
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