CN105853641A - 一种接骨紫金散及其制备方法 - Google Patents
一种接骨紫金散及其制备方法 Download PDFInfo
- Publication number
- CN105853641A CN105853641A CN201610194703.1A CN201610194703A CN105853641A CN 105853641 A CN105853641 A CN 105853641A CN 201610194703 A CN201610194703 A CN 201610194703A CN 105853641 A CN105853641 A CN 105853641A
- Authority
- CN
- China
- Prior art keywords
- mass
- zijin
- synthetism
- raw material
- dissipates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 title abstract description 5
- 239000000843 powder Substances 0.000 title abstract description 5
- 239000002994 raw material Substances 0.000 claims abstract description 26
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 19
- 239000004863 Frankincense Substances 0.000 claims abstract description 14
- 239000012535 impurity Substances 0.000 claims abstract description 4
- 238000007873 sieving Methods 0.000 claims abstract description 4
- 238000004806 packaging method and process Methods 0.000 claims abstract description 3
- 239000000203 mixture Substances 0.000 claims description 19
- 241001489978 Eupolyphaga Species 0.000 claims description 18
- 241001057584 Myrrha Species 0.000 claims description 18
- 239000009286 sanguis draxonis Substances 0.000 claims description 18
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 claims description 17
- 235000006226 Areca catechu Nutrition 0.000 claims description 17
- 239000000470 constituent Substances 0.000 claims description 16
- 241000717739 Boswellia sacra Species 0.000 claims description 13
- 244000080767 Areca catechu Species 0.000 claims description 11
- 238000002360 preparation method Methods 0.000 claims description 7
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 3
- 229910052802 copper Inorganic materials 0.000 claims description 3
- 239000010949 copper Substances 0.000 claims description 3
- 210000000481 breast Anatomy 0.000 claims 5
- 235000009508 confectionery Nutrition 0.000 claims 1
- 210000000582 semen Anatomy 0.000 claims 1
- 208000010392 Bone Fractures Diseases 0.000 abstract description 17
- 210000000988 bone and bone Anatomy 0.000 abstract description 16
- 208000026137 Soft tissue injury Diseases 0.000 abstract description 14
- 230000000694 effects Effects 0.000 abstract description 12
- 244000235603 Acacia catechu Species 0.000 abstract description 7
- 230000017531 blood circulation Effects 0.000 abstract description 6
- 239000011505 plaster Substances 0.000 abstract description 6
- 230000001737 promoting effect Effects 0.000 abstract description 6
- 230000036407 pain Effects 0.000 abstract description 5
- 210000003734 kidney Anatomy 0.000 abstract description 4
- 208000008822 Ankylosis Diseases 0.000 abstract description 3
- 206010023198 Joint ankylosis Diseases 0.000 abstract description 3
- 230000008961 swelling Effects 0.000 abstract description 3
- 210000002435 tendon Anatomy 0.000 abstract description 3
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 1
- 235000006020 Acacia catechu Nutrition 0.000 abstract 1
- 235000003717 Boswellia sacra Nutrition 0.000 abstract 1
- 240000007551 Boswellia serrata Species 0.000 abstract 1
- 235000012035 Boswellia serrata Nutrition 0.000 abstract 1
- 241000131329 Carabidae Species 0.000 abstract 1
- 240000007311 Commiphora myrrha Species 0.000 abstract 1
- 235000006965 Commiphora myrrha Nutrition 0.000 abstract 1
- 244000124209 Crocus sativus Species 0.000 abstract 1
- 235000015655 Crocus sativus Nutrition 0.000 abstract 1
- 244000241257 Cucumis melo Species 0.000 abstract 1
- 235000009847 Cucumis melo var cantalupensis Nutrition 0.000 abstract 1
- 241000123589 Dipsacus Species 0.000 abstract 1
- 235000007265 Myrrhis odorata Nutrition 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 229940116229 borneol Drugs 0.000 abstract 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- NIFIFKQPDTWWGU-UHFFFAOYSA-N pyrite Chemical compound [Fe+2].[S-][S-] NIFIFKQPDTWWGU-UHFFFAOYSA-N 0.000 abstract 1
- 229910052683 pyrite Inorganic materials 0.000 abstract 1
- 239000011028 pyrite Substances 0.000 abstract 1
- 230000003014 reinforcing effect Effects 0.000 abstract 1
- 239000011347 resin Substances 0.000 abstract 1
- 229920005989 resin Polymers 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 21
- 206010017076 Fracture Diseases 0.000 description 15
- 208000024779 Comminuted Fractures Diseases 0.000 description 7
- 210000003205 muscle Anatomy 0.000 description 7
- 239000008280 blood Substances 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 208000034656 Contusions Diseases 0.000 description 4
- 206010024453 Ligament sprain Diseases 0.000 description 4
- 208000034526 bruise Diseases 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 206010052428 Wound Diseases 0.000 description 3
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 238000005728 strengthening Methods 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 206010061363 Skeletal injury Diseases 0.000 description 2
- 210000003797 carpal joint Anatomy 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 210000004394 hip joint Anatomy 0.000 description 2
- 238000009940 knitting Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 206010002027 Amyotrophy Diseases 0.000 description 1
- 206010003694 Atrophy Diseases 0.000 description 1
- 241001172538 Daemonorops draco Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 206010020649 Hyperkeratosis Diseases 0.000 description 1
- 208000002565 Open Fractures Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000037444 atrophy Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 210000002683 foot Anatomy 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 210000000281 joint capsule Anatomy 0.000 description 1
- 230000002232 neuromuscular Effects 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000000399 orthopedic effect Effects 0.000 description 1
- 208000024335 physical disease Diseases 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- OARRHUQTFTUEOS-UHFFFAOYSA-N safranin Chemical compound [Cl-].C=12C=C(N)C(C)=CC2=NC2=CC(C)=C(N)C=C2[N+]=1C1=CC=CC=C1 OARRHUQTFTUEOS-UHFFFAOYSA-N 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Insects & Arthropods (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
本发明公开了一种接骨紫金散及其制备方法，原料组分及各组分质量百分含量如下：乳香5％‑20％，没药5％‑20％，续断5％‑20％，儿茶5％‑20％，血竭5％‑30％，土鳖虫5％‑20％，甜瓜子5％‑20％，藏红花5％‑20％，自然铜5％‑20％，冰片5％‑20％。将各原料烘干后，混合均匀，粉碎，过筛去除杂质，按份单独包装，干燥处储藏。本发明的接骨紫金散，具有活血化瘀、消肿止痛、续筋接骨、补肾壮骨等功能，可有效预防各种骨折，骨裂缝，骨不愈合，石膏固定后关节僵硬引起的伸屈困难，同时对对软组织损伤有较好的疗效，见效快，安全无副作用。
Description
技术领域
本发明属于中药技术领域，具体涉及一种接骨紫金散及其制备方法。
背景技术
长期以来中医正骨临床对新鲜骨折，软组织损伤的各种治疗具足，但效果侧次不齐。如骨不愈合，关节僵硬，关节囊萎缩，肌肉萎缩，神经肌肉粘连等，除外科手术外没有确切稳定的疗效。各种骨折、骨裂缝、骨不愈合、石膏固定后关节僵硬引起的伸屈困难都很棘手，如果骨折初期外敷活血祛瘀的中药情况会大有改观。目前多数医院骨科还是以单纯石膏固定为主，并无外敷接骨散。患者早期血肿吸收往往很慢，既影响骨痂形成又妨碍早期功能锻炼。临床医师多以口服消炎镇痛药和输液辅助治疗，再无它法。
发明内容
为了解决上述问题，本发明提供一种接骨紫金散及其制备方法，具有活血化瘀、消肿止痛、续筋接骨、补肾壮骨等功能，可有效预防各种骨折，骨裂缝，骨不愈合，石膏固定后关节僵硬引起的伸屈困难，同时对对软组织损伤有较好的疗效。
为了实现上述目的，本发明采用的技术手段为：
一种接骨紫金散，原料组分及各组分质量百分含量如下：乳香5％-20％，没药5％-20％，续断5％-20％，儿茶5％-20％，血竭5％-30％，土鳖虫5％-20％，甜瓜子5％-20％，藏红花5％-20％，自然铜5％-20％，冰片5％-20％。
一种接骨紫金散，原料组分及各组分质量百分含量优选如下：乳香5％-10％，没药5％-10％，续断5％-15％，儿茶10％-20％，血竭10％-30％，土鳖虫5％-15％，甜瓜子10％-15％，藏红花5％-10％，自然铜5％-10％，冰片5％-10％。
一种接骨紫金散，原料组分及各组分质量百分含量优选如下：乳香5％，没药10％，续断10％，儿茶10％，血竭15％，土鳖虫10％，甜瓜子10％，藏红花10％，自然铜10％，冰片10％。
一种接骨紫金散，原料组分及各组分质量百分含量优选如下：乳香10％，没药10％，续断15％，儿茶15％，血竭10％，土鳖虫10％，甜瓜子10％，藏红花10％，自然铜5％，冰片5％。
一种接骨紫金散，原料组分及各组分质量百分含量优选如下：乳香10％，没药5％，续断5％，儿茶20％，血竭10％，土鳖虫15％，甜瓜子15％，藏红花10％，自然铜5％，冰片5％。
一种接骨紫金散，原料组分及各组分质量百分含量优选如下：乳香10％，没药10％，续断10％，儿茶10％，血竭30％，土鳖虫5％，甜瓜子10％，藏红花5％，自然铜5％，冰片5％。
所述一种接骨紫金散的制备方法，将各原料烘干后，混合均匀，粉碎，过筛去除杂质，每10克为一份单独包装，干燥处储藏。
本发明中所述血竭(Daemonorops draco Bl.)、乳香、没药、续断、儿茶、土鳖虫、甜瓜子、藏红花、自然铜和冰片均为本领域技术人员熟知的中药组分，可以从普通商业途径获得。
本发明药物组分的用量是经过发明人进行大量摸索总结得出的，各组分用量在上述范围都有较好的疗效。以上组成中的中药原料，尤其是佐药和使药可以用适当的具有相同药性的中药替换，替换后的中药制剂其药物作用不变。
本发明的中药制剂，是通过将上述配方组成的中药原料经过提取或其他方式加工，制成药物活性物质，随后，以该物质为原料，需要时加入药物可接受的载体，按照制剂学的常规技术制成。所述活性物质可以通过分别提取中药原料得到，也可以通过共同提取中药原料得到，也可以通过其他方式得到，如：粉碎、压榨、煅烧、研磨、过筛、萃取、水提、醇提、酯提、层析等常规方法得到。
本发明接骨紫金散可以用作骨折、关节僵硬引起的伸屈困难以及软组织损伤的内服治疗，无论老年人、中年人、青年人和少幼，还是粉碎性骨折或开放性骨折，均已临床治愈成功。
临床研究证明本发明接骨紫金散对新鲜骨折具有促进骨折早期愈合的作用。具有活血化瘀、消肿止痛、续筋接骨、补肾壮骨等功能。配合夹板外固定，早期功能锻炼，已达到快速临床治愈标准。
本发明提供的接骨紫金散可有效预防各种骨折，骨裂缝，骨不愈合，石膏固定后关节僵硬引起的伸屈困难。
本发明提供的接骨紫金散对软组织损伤新伤如：腰扭伤，踝关节扭伤，颈部扭挫伤，髋关节扭伤，腕关节扭挫伤，踝关节扭伤，颈部扭挫伤，髋关节扭伤，腕关节扭挫伤等消肿奇快。一般骨伤、软组织损伤使用接骨散后10-30天骨伤、软组织损伤就基本痊愈了。
本发明接骨紫金散为外敷药，以外敷法治疗，1个损伤部位使用一份药(可根据具体情况酌情加减)，一周换药一次，一般骨折新伤使用7天就能止痛消肿，活血化瘀，3-4份药达到临床治愈标准，严重的、陈伤需要6份药。软组织损伤新伤一般1-2副药就治愈了。严重的需要3-6副药。
有益效果：
本发明的接骨紫金散，具有活血化瘀、消肿止痛、续筋接骨、补肾壮骨等功能，可有效预防各种骨折，骨裂缝，骨不愈合，石膏固定后关节僵硬引起的伸屈困难，同时对对软组织损伤有较好的疗效，见效快，安全无副作用。
具体实施方式
以下实施例中血竭、乳香、没药、续断、儿茶、土鳖虫、甜瓜子、藏红花、自然铜和冰片由高碑店正人堂医药直供。
实施例1
一种接骨紫金散，原料组分及各组分质量百分含量如下：乳香5％，没药10％，续断10％，儿茶10％，血竭15％，土鳖虫10％，甜瓜子10％，藏红花10％，自然铜10％，冰片10％。
实施例2
一种接骨紫金散，原料组分及各组分质量百分含量如下：乳香10％，没药10％，续断15％，儿茶15％，血竭10％，土鳖虫10％，甜瓜子10％，藏红花10％，自然铜5％，冰片5％。
实施例3
一种接骨紫金散，原料组分及各组分质量百分含量如下：乳香10％，没药5％，续断5％，儿茶20％，血竭10％，土鳖虫15％，甜瓜子15％，藏红花10％，自然铜5％，冰片5％。
实施例4
一种接骨紫金散，原料组分及各组分质量百分含量如下：乳香10％，没药10％，续断10％，儿茶10％，血竭30％，土鳖虫5％，甜瓜子10％，藏红花5％，自然铜5％，冰片5％。
将各原料烘干后，混合均匀，粉碎，过筛去除杂质，每10克为一份单独包装，干燥处储藏。
经过近40年的临床试验，取得了较好的疗效，有关临床试验情况详述如下：
1、病人概况：选择对象为骨折、粉碎性骨折、软组织损伤、关节肌肉淤血；
2、年龄为20-80岁，性别不限。
2、病例入组标准：根据骨科疾病诊断标准，排除严重躯体疾病，治疗前停用各种内、外用药剂。
3、治疗方案：选择病例500例，其中：
骨折100例：治疗组50例；对照组50例；
粉碎性骨折200例：治疗组100例；对照组100例；
软组织损伤100例：治疗组50例；对照组50例；
关节肌肉淤血100例：治疗组50例；对照组50例；
4、治疗方法：治疗组使用本发明的接骨紫金散，外敷，每周换药一次，每次一包(每包10克)；对照组采用住院治疗。
5、疗效评定：
1)、痊愈：症状和体征完全消除，骨折或粉碎性骨折或软组织损伤或关节肌肉淤血完全修复；
2)、显效：症状和体征大部分消除，骨折或粉碎性骨折或软组织损伤或关节肌肉淤血基本修复；
3)、有效：症状和体征明显有所好转，骨折或粉碎性骨折或软组织损伤或关节肌肉淤血有所修复；
4)、无效：病症及体征没有明显好转，骨折或粉碎性骨折或软组织损伤或关节肌肉淤血没有修复迹象。
6、疗效评定结果：
7、通过对两组进行比较分析，使用本发明的接骨紫金散的治疗组临床效果明显高于使用常规西药对照组；具体参照下表：
| 例数 | 痊愈 | 显效 | 有效 | 无效 | 愈显率 | 总有效率 | |
| 治疗组 | 250 | 213 | 33 | 3 | 1 | 98.4％ | 99.6％ |
| 对照组 | 250 | 128 | 84 | 30 | 8 | 84.8％ | 96.8％ |
Claims (7)
1.一种接骨紫金散，其特征在于，原料组分及各组分质量百分含量如下：乳香5％-20％，没药5％-20％，续断5％-20％，儿茶5％-20％，血竭5％-30％，土鳖虫5％-20％，甜瓜子5％-20％，藏红花5％-20％，自然铜5％-20％，冰片5％-20％。
2.根据权利要求1所述的一种接骨紫金散，其特征在于，原料组分及各组分质量百分含量如下：乳香5％-10％，没药5％-10％，续断5％-15％，儿茶10％-20％，血竭10％-30％，土鳖虫5％-15％，甜瓜子10％-15％，藏红花5％-10％，自然铜5％-10％，冰片5％-10％。
3.根据权利要求2所述的一种接骨紫金散，其特征在于，原料组分及各组分质量百分含量如下：乳香5％，没药10％，续断10％，儿茶10％，血竭15％，土鳖虫10％，甜瓜子10％，藏红花10％，自然铜10％，冰片10％。
4.根据权利要求2所述的一种接骨紫金散，其特征在于，原料组分及各组分质量百分含量如下：乳香10％，没药10％，续断15％，儿茶15％，血竭10％，土鳖虫10％，甜瓜子10％，藏红花10％，自然铜5％，冰片5％。
5.根据权利要求2所述的一种接骨紫金散，其特征在于，原料组分及各组分质量百分含量如下：乳香10％，没药5％，续断5％，儿茶20％，血竭10％，土鳖虫15％，甜瓜子15％，藏红花10％，自然铜5％，冰片5％。
6.根据权利要求2所述的一种接骨紫金散，其特征在于，原料组分及各组分质量百分含量如下：乳香10％，没药10％，续断10％，儿茶10％，血竭30％，土鳖虫5％，甜瓜子10％，藏红花5％，自然铜5％，冰片5％。
7.权利要求1至6中任意一项所述一种接骨紫金散的制备方法，其特征在于，将各原料烘干后，混合均匀，粉碎，过筛去除杂质，每10克为一份单独包装，干燥处储藏。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610194703.1A CN105853641A (zh) | 2016-03-29 | 2016-03-29 | 一种接骨紫金散及其制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610194703.1A CN105853641A (zh) | 2016-03-29 | 2016-03-29 | 一种接骨紫金散及其制备方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105853641A true CN105853641A (zh) | 2016-08-17 |
Family
ID=56626617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610194703.1A Pending CN105853641A (zh) | 2016-03-29 | 2016-03-29 | 一种接骨紫金散及其制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105853641A (zh) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108619350A (zh) * | 2018-08-03 | 2018-10-09 | 吉林省九成科技开发有限公司 | 一种接骨续筋散及其制备方法 |
| CN110478425A (zh) * | 2019-08-19 | 2019-11-22 | 黑龙江蒿氏健康科技有限责任公司 | 一种治疗颈肩腰腿痛的贴膏 |
| CN117838791A (zh) * | 2023-03-31 | 2024-04-09 | 吴昊 | 一种消瘀续筋接骨散配方及工艺 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101239132A (zh) * | 2008-01-15 | 2008-08-13 | 孟宪铎 | 一种治疗骨折、跌打损伤的强力接骨药物 |
-
2016
- 2016-03-29 CN CN201610194703.1A patent/CN105853641A/zh active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101239132A (zh) * | 2008-01-15 | 2008-08-13 | 孟宪铎 | 一种治疗骨折、跌打损伤的强力接骨药物 |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108619350A (zh) * | 2018-08-03 | 2018-10-09 | 吉林省九成科技开发有限公司 | 一种接骨续筋散及其制备方法 |
| CN110478425A (zh) * | 2019-08-19 | 2019-11-22 | 黑龙江蒿氏健康科技有限责任公司 | 一种治疗颈肩腰腿痛的贴膏 |
| CN117838791A (zh) * | 2023-03-31 | 2024-04-09 | 吴昊 | 一种消瘀续筋接骨散配方及工艺 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101623415B (zh) | 一种治疗骨折骨伤的中药制剂 | |
| CN101703757B (zh) | 续筋活血接骨膏及其制备方法 | |
| CN105853641A (zh) | 一种接骨紫金散及其制备方法 | |
| CN101322786B (zh) | 一种治疗骨折、跌打损伤的外用药物 | |
| CN103566278B (zh) | 接骨丹 | |
| CN102342983B (zh) | 一种治疗腰腿疼痛的中药组合物及其制剂的制备方法 | |
| CN104225283B (zh) | 一种治疗颈椎、肩周炎、腰椎间盘突出、风湿性关节炎和类风湿性关节炎的中药内服药和膏药 | |
| CN102600256A (zh) | 一种用于跌打损伤中药组合物 | |
| CN103027978A (zh) | 一种治疗跌打损伤的药物组合物及其制备方法 | |
| CN104083569A (zh) | 一种接骨膏药及其制备方法 | |
| CN104083568A (zh) | 一种苗医骨痛膏药及其制备方法 | |
| CN109432309B (zh) | 中药组合物、外用药酒及其制备方法和应用 | |
| CN1927371A (zh) | 活血丹及其制备方法 | |
| CN103301215B (zh) | 一种治疗骨质疾病的药物组合物及其制备方法与用途 | |
| CN1290540C (zh) | 一种治疗骨折的内服中药及其配合使用的外敷中药 | |
| CN105748800A (zh) | 一种接骨紫金丹及其制备方法 | |
| CN113041323A (zh) | 一种治疗骨折的药物 | |
| CN112022940A (zh) | 一种用于治疗颈肩腰腿痛及癌痛的药物配方 | |
| CN1055862C (zh) | 一种治疗骨坏死疾病的中药制剂 | |
| CN105664013A (zh) | 一种生大黄复方跌打损伤外用止痛消肿软膏 | |
| CN103127344B (zh) | 治疗骨折不愈合、骨折迟缓性愈合的中药制剂及制备方法 | |
| CN103417944A (zh) | 消肿活血续骨膏及其制备方法 | |
| CN116173160B (zh) | 一种外用消肿止痛组方及其应用 | |
| CN1074679C (zh) | 治疗骨伤的中药复方制剂 | |
| CN107823392A (zh) | 一种接骨膏药及其制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160817 |