CN105853506A - Hypotensive healthcare medicine composition containing five-leaf gynostemma herb - Google Patents
Hypotensive healthcare medicine composition containing five-leaf gynostemma herb Download PDFInfo
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- CN105853506A CN105853506A CN201610301725.3A CN201610301725A CN105853506A CN 105853506 A CN105853506 A CN 105853506A CN 201610301725 A CN201610301725 A CN 201610301725A CN 105853506 A CN105853506 A CN 105853506A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/424—Gynostemma
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
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Abstract
The invention discloses a hypotensive healthcare medicine composition containing five-leaf gynostemma herb. The hypotensive healthcare medicine composition is prepared by mixing, by mass, 30-70% of the five-leaf gynostemma herb, 10-50 parts of Folium eucommia, 4-20% of frosted mulberry leaf, 2-10% of Radix codonopsis, 2-10% of Pueraria mirifica, 1-5% of America Eryngium foetidum and 1-5% of Achillea millefolium, wherein the five-leaf gynostemma herb is formed by proportionally mixing diploid five-leaf gynostemma herb and tetraploid five-leaf gynostemma herb. The hypotensive healthcare medicine composition has excellent hypotensive effect and good treatment effect on hyperglycemia and hyperlipidemia.
Description
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of antihypertensive health care medicine containing Herb Gynostemmae Pentaphylli
Compositions.
Background technology
Hyperlipidemia, hypertension, hyperglycemia, be commonly called as " three high ", is that current China has influence on people
The big problem that class is healthy, the crowd of the such issues that whole nation is existing reach several hundred million more than, but also by
Year increases.Many developed countries the most generally also exist this big problem in the world, are also medical circles
A difficult problem." three high " is the source of mankind's numerous disease and subhealth state, along with " three high "
Development and deterioration, a series of disease and complication can be caused, highly impact the mankind's
Health or even life-span.
Hypertension is the disease of lasting hyperpiesia, can cause apoplexy, heart disease, hemangioma,
The diseases such as renal failure, hypertension is that a kind of rising with blood pressure is characterized, can with heart, blood vessel,
Brain and the systemic disease of the functional or organic change of kidney and other organs.Cause the former of hypertension
Cause: one is that blood vessel follows the string, and makes blood difficulty of transportation, it has to strengthen blood pressure and make blood stream
Obtain ratio smoothly;Two is blood fat, cholesterol height, and the viscosity causing blood is high, works as blood
Viscosity increase after, on blood vessel deposition attachment get more and more, the speed of blood flow is more come
The slowest and cause hypertension.
At present medical circle to the preventing and treating of " three high " based on Western medicine, these medicines need be for a long time
To taking all the life, not only spend big, and have certain side effect.Preferably preventing and treating " three
High " means should be early preventions, early intervene, based on the synthetic prescription of health plant, and join
With good living habit.The most safe and effective, have no side effect, moreover it is possible to by these
The plant of tonification makes people more healthy.
Summary of the invention
For solving the problems referred to above, the invention provides a kind of antihypertensive health care medicine group containing Herb Gynostemmae Pentaphylli
Compound, by medical material compatibilities such as Herb Gynostemmae Pentaphylli and Folium Mori, Folium Eucommiae, Radix Codonopsis, Radix Puerariaes, removes
The dirt of blood inwall, rubbish and toxin, make blood unblocked at Ink vessel transfusing, makes the heart, brain,
The blood vessel of kidney, liver and each internal organs is softened, and makes the cell of aging clear out in human body,
The self regulation making human body recovers normal.
Described Herb Gynostemmae Pentaphylli (Gynostemma Pentaphyllum) is that Cucurbitaceae Gynostemma is many
Year SHENGCAO matter liana.The whole world has had been found that 16 kind of 3 subspecies, and there be 11 kind of 1 Asia in China
Kind, flat interest has 6 kinds of subspecies (short stalk, long stalk, Herba Gynostemmatis, white hair, light leaf, sweet taste, beak
Really), Herb Gynostemmae Pentaphylli is distributed mainly on the south the Qinling Mountains, all provinces and regions, the Yangtze river basin.Like dark and damp, scattering
At the bottom of rock between light, fertile soil, height above sea level 200 1500 meters, limes marginis, the environment of sylvan life.Strand
What stock was blue is mainly composed of soaping agents, flavonoid, polysaccharide and zinc, selenium, ferrum, calcium, magnesium etc.
Trace element, vitamin A, B etc..There is regulation human physiological functions, strengthen human immunity
Power, offsets the functions such as sugar skin hormone side effect, antioxidation, blood fat reducing.
Herb Gynostemmae Pentaphylli has many different kinds and cenospecies (initially coming) from wild species domestication,
Nature also has different times gonosomes (2X, 4X, 6X ...).Between the most of the same race, different
Between times gonosome, its bioactive functions and effective ingredient are widely different.And between different sources
Its difference is the biggest, especially saponin, Polyphenols, flavonoid and trace element-selenium etc., all
There is the biggest difference.According to us from the point of view of the analysis that U.S.'s laboratory is carried out, China and the world
The different Herb Gynostemmae Pentaphylli that upper different regions produce, its effective ingredient is the most widely different, and also
Not having a kind of single Herb Gynostemmae Pentaphylli is best on all principle active component.In all analyses
In sample, the Polyphenols that the diploid Herb Gynostemmae Pentaphylli of Shaanxi The Fiveleaf Gynostemma Research Institute of Pingli County analyzes and
Flavone content is the highest, and the content of the saponin of the tetraploid Herb Gynostemmae Pentaphylli of this institute and selenium is also all
Detecting in sample best, its total saponin content averagely reaches 8.5%.And plant difference portion
In Wei, no matter diploid or tetraploid, all effective ingredient with plant leaf are ideal.Close
The gynostemma pentaphylla dispensing (2X+4X) of reason, rich in various health factors, can be effectively reduced cholesterol
Thus reach blood fat reducing, vessel softening, promotion cardiovascular function, thus reach to regulate the work of blood pressure
With, and blood glucose also can be played certain regulation effect by its effective active composition.
The present invention is based on analysis for many years and research, and the cooperation with Univ Maryland-Coll Park USA is ground
Studying carefully, Herb Gynostemmae Pentaphylli various to various places have carried out system and careful analysis, detect and study.Thoroughly
Change over the most always based on the formula of single Herb Gynostemmae Pentaphylli, and be solely focused on strand
The thinking of the blue Saponin of stock.The combination side that the present invention is new is the soap from the most comprehensive comprehensive Herb Gynostemmae Pentaphylli
Glycoside, polyphenol compound, flavone compound, mineral (especially selenium), polysaccharide are raw
Active substances is started with.In proportion the Herb Gynostemmae Pentaphylli diploid of specific place of production certain species and four times
Body combination of materials becomes a brand-new Herb Gynostemmae Pentaphylli novel species formula.
The present invention is according to the bioactive ingredients detected, the health-care medicinal of compatibility selenium-rich so that it is
Totally the effect to conditioning three-hypers further enhances, if often taking, can not only regulate and control three
Height, also can promote the health of the vital organs of the human body, but also be free from side effects.
The same eucommia bark of Folium Eucommiae merit, is exactly the good medicine of strong internal organs since ancient times, and Folium Eucommiae is rich
Rich multiple Flavonoid substances and multiple phenolic acid can effectively facilitate cardiovascular health and coronary blood flow
Amount, and have detected that multiple (about 27 kinds) wood lipoid substance, particularly (+)-Pinoresinol two
This compound of glucoside has well regulation blood pressure function.
Alkaloid in Folium Mori and polysaccharides of Folium Mori can promote the activity of insulin β cell, especially
Be distinctive DNJ in Folium Mori (I-deoxynojirimycin) be potent carbohydrate metabolism enzyme inhibitor,
Insulin resistant can be effectively improved, and the multiple Flavonoid substances in Folium Mori also has regulation three-hypers
Effect.
Radix Puerariae grows for many years at selenium-rich soil, and Se content is abundant and rich in isoflavone, from ancient times with
Come just quench one's thirst for the deficiency of YIN, diarrhea due to hypofunction of the spleen, yang invigorating antidiarrheal, liver-protecting and stomach-nourishing, to vascular system also
There is good regulation effect, at aspects such as coronary artery dilator, blood fat reducing, blood pressure lowering, regulation blood glucose
The most powerful.
Radix Codonopsis nature and flavor are sweet flat, return spleen, lung meridian.Invigorating middle warmer, QI invigorating, promote the production of body fluid.Control weakness of the spleen and stomach,
Deficiency of both QI and blood, fatigue and lack of strength, lack of appetite, thirsty, chronic diarrhea, proctoptosis.Place of production north of China height above sea level
In the woods limit, mountain region of 1560-3100 rice and shrubbery.Radix Codonopsis is traditional tonic that China is conventional,
The flat interest Eight Immortals Radix Codonopsis that flat interest area, Shaanxi produces is known in China and abroad, and has invigorating the spleen and replenishing QI, spleen invigorating benefit
Effect of lung.Radix Codonopsis has enhancing immunity, expansion blood vessel, blood pressure lowering, improves microcirculation, enhancing
Hemopoietic functions etc. act on.
America thorn Coriander (Eryugium foetidum) originates in Centro-American and Caribbean ground
District, is planted by the whole world.As edible medicinal herbs, its fragrant has a kind of normal with us
The Rhizoma et radix valerianae (Coriander) eaten is similar, but has no bearing on Coriander.In Caribbean, local
People throughout the year this medical material as preventing and treating the omnipotent plant of all kinds of diseases and ailments, and a lot of area edible it be also for
The effect of its health care and nutrition.In Latin America and Central America, this plant the most widely eats
Material, but also have the longest history as the medical material preventing and treating hypertension, and have certain curative effect.
Common milfoil (Achillea millefolium), also Cheng Heye Millefolium, pool, west achillea millefolium, former
Produce Eurasia and North America.Owing to the floral leaf of its beauty is extensively planted by the world.Much
Area is also as edible medicinal herbs and the material made tea, and common milfoil is kind of a broad-spectrum guarantor
Being good for medical material, it can directly affect bone marrow and promote the renewal of blood, and it can improve the circulation of blood,
Blood pressure lowering, improves varicosis, therefore, is ideal for other medical material antihypertensive health cares of compatibility
Choosing.
For reaching above-mentioned purpose, the technical solution used in the present invention is:
A kind of antihypertensive health care pharmaceutical composition containing Herb Gynostemmae Pentaphylli, it is characterised in that described health care medicinal
Compositions with Herb Gynostemmae Pentaphylli, Folium Eucommiae, Folium Mori, Radix Codonopsis, Radix Puerariae, America thorn Coriander,
Common milfoil is that mixed raw material becomes, and is according to the mass fraction: Herb Gynostemmae Pentaphylli 30~70%, Folium Eucommiae
10~50%, Folium Mori 4~20%, Radix Codonopsis 2~10%, Radix Puerariae 2~10%, America thorn Coriander
1~5%, common milfoil 1~5%.
Further, described health medicine compositions is pressed from following raw material and is made with mass fraction
Become: Herb Gynostemmae Pentaphylli 40~60%, Folium Eucommiae 20~40%, Folium Mori 6~15%, Radix Codonopsis 2~6%,
Radix Puerariae 2~6%, America thorn Coriander 1~4%, common milfoil 1~4%.
Further, in described health medicine compositions, each raw material is according to the mass fraction: strand
Indigo plant 50%, Folium Eucommiae 30%, Folium Mori 10%, Radix Codonopsis 3%, Radix Puerariae 3%, America thorn
Coriander 2%, common milfoil 2%.
Further, described Herb Gynostemmae Pentaphylli is diploid Herb Gynostemmae Pentaphylli blade and tetraploid Herb Gynostemmae Pentaphylli blade
Mix.
Further, the most described diploid Herb Gynostemmae Pentaphylli blade: tetraploid Herb Gynostemmae Pentaphylli
Blade=2:5~5:2.Preferably, described diploid Herb Gynostemmae Pentaphylli blade: tetraploid leaf of Herb Gynostemmae Pentaphylli
Sheet=1:1.
Further, described health medicine compositions makes tablet, pill, electuary, granule.
The present invention by Herb Gynostemmae Pentaphylli and the mutual compatibility of multiple medical material, remove blood inwall dirt,
Rubbish and toxin, make blood unblocked at Ink vessel transfusing, makes the heart, brain, kidney, liver and each internal organs
Blood vessel softened, make aging cell clear out in human body, make human body oneself tune
Joint recovers normal.Reasonably gynostemma pentaphylla dispensing (2X+4X) cholesterol can be effectively reduced thus
Reach blood fat reducing, vessel softening, promotion cardiovascular function, thus reach to regulate the effect of blood pressure,
And blood glucose also can be played certain regulation effect by its effective active composition.
The present invention use diploid and tetraploid Herb Gynostemmae Pentaphylli and Folium Mori, Folium Eucommiae, Radix Codonopsis and
The Traditional health care drug matchings such as Radix Puerariae, and add America thorn Coriander and common milfoil, can effectively promote
Enter the self-regulating function of health, thus reach dredging blood vessel, exhale the old and inhale the new, strong dirty
Internal organs, reduction " three high ".This formula is all formed by the plant compatibility of unsoundness benefiting action,
Compared with Western medicine, not only low cost, have no side effect, and can also provide many useful for people's body
The nutrient substance such as healthy saponin, Polyphenols, flavonoid, polysaccharide and mineral element, make people
Body is more healthy.
Detailed description of the invention
Below in conjunction with embodiment, further instruction of the present invention, the percentage ratio in embodiment are
Percentage by weight, but the invention is not limited in this.
Embodiment 1
Diploid Herb Gynostemmae Pentaphylli 25%, tetraploid Herb Gynostemmae Pentaphylli 25%, Folium Eucommiae 30%,
Folium Mori 10%, Radix Codonopsis 3%, Radix Puerariae 3%, America thorn Coriander 2%, common milfoil 2%
Embodiment 2
Diploid Herb Gynostemmae Pentaphylli 20%, tetraploid Herb Gynostemmae Pentaphylli 50%, the Cortex Eucommiae 20%, Folium Mori 4%,
Radix Codonopsis 2%, Radix Puerariae 2%, America thorn Coriander 1%, common milfoil 1%
Embodiment 3
Diploid Herb Gynostemmae Pentaphylli 50%, tetraploid Herb Gynostemmae Pentaphylli 20%, the Cortex Eucommiae 12%, Folium Mori 5%,
Radix Codonopsis 6%, Radix Puerariae 3%, America thorn Coriander 2%, common milfoil 2%
Embodiment 4
Diploid Herb Gynostemmae Pentaphylli 25%, tetraploid Herb Gynostemmae Pentaphylli 25%, Folium Eucommiae 40%, Folium Mori
3%, Radix Codonopsis 3%, Radix Puerariae 2%, America thorn Coriander 1%, common milfoil 1%
Embodiment 5
Diploid Herb Gynostemmae Pentaphylli 30%, tetraploid Herb Gynostemmae Pentaphylli 20%, Folium Eucommiae 20%, Folium Mori
12%, Radix Codonopsis 5%, Radix Puerariae 5%, America thorn Coriander 4%, common milfoil 4%
Embodiment 6
Diploid Herb Gynostemmae Pentaphylli 20%, tetraploid Herb Gynostemmae Pentaphylli 30%, Folium Eucommiae 30%, Folium Mori
14%, Radix Codonopsis 2%, Radix Puerariae 2%, America thorn Coriander 1%, common milfoil 1%
Embodiment 7
Diploid Herb Gynostemmae Pentaphylli 30%, tetraploid Herb Gynostemmae Pentaphylli 15%, Folium Eucommiae 25%, Folium Mori
15%, Radix Codonopsis 6%, Radix Puerariae 5%, America thorn Coriander 2%, common milfoil 2%
Embodiment 8
Diploid Herb Gynostemmae Pentaphylli 30%, tetraploid Herb Gynostemmae Pentaphylli 30%, Folium Eucommiae 10%, Folium Mori
10%, Radix Codonopsis 6%, Radix Puerariae 6%, America thorn Coriander 4%, common milfoil 4%
Embodiment 9
By the product in the embodiment of the present invention 1~8 according to country's selenium-enriched food standard
" GB28050-2011 " detects, and testing result shows that selenium constituent content of the present invention exists
0.20~5.00mg/kg, meet selenium-enriched food product standard.With high performance liquid chromatography (HPLC)
Based on improvement new technique detect in its product and contain: saponin 108.4~188.2mg/g;
Polyphenol 23.5~37.5mg/g;Total flavones 22.5~36.5mg/g.
Embodiment 10
1, clinical data
Gently, moderate hypertension, all meet the whole nation hypertension meeting formulate diagnostic criteria.Altogether
80 examples, male 46 examples, female 34 example.Age 40-68 year, average 49 ± 15.6 years old.Compound recipe twists
The blue blood-pressure decreasing tea of stock is drunk for medicine, each 3-5 gram, and three times a day, every recording blood pressure changes, and within 2 weeks, is
1 course for the treatment of, carry out liver function, kidney merit inspection simultaneously.Blood pressure before age, sex and treatment between patient
Level there are no significant difference.Other is not all applied to affect the medicine of blood pressure.
2, efficacy assessment standard:
Sentence with reference to curative effect in Ministry of Health of the People's Republic of China's " Clinical Researches of New Drugs guideline "
Disconnected standard.Jiaogulan in treating hypertension criterion of therapeutical effect is effective: diastolic pressure decline >=1.3kPa
(10mmHg) to normal or decline more than 2.7kPa (20mmHg);Effective: diastolic pressure
Decline not up to 1.3kPa (10mmHg) but be down to normal or decline 1.3-2.5kPa, as
Systolic hypertension, it is also effective for shrinking drops > 4.OkPa (30n mmHg);Invalid:
Blood pressure drops is not up to above-mentioned scope.
3, therapeutic outcome
The forward and backward blood pressure level of Therapy of Patients with Hypertension be relatively shown in Table 1,
Clinical efficacy is shown in Table 2.
The comparison (X ± S kPa) of each group of blood pressure level before and after blood pressure patient treatment of table 1
The clinical effectiveness of table 2 compound gynostemma pentaphylla blood-pressure decreasing tea
Although the present invention describes with reference to specific embodiment as above, but the art
Those of ordinary skill it should be appreciated that above example is only to illustrate rather than
Limit the present invention, if in the spirit of the present invention to the change of above-described embodiment,
Modification all should fall in the range of following claims is claimed.
Claims (7)
1. the antihypertensive health care pharmaceutical composition containing Herb Gynostemmae Pentaphylli, it is characterised in that described health care
Pharmaceutical composition with Herb Gynostemmae Pentaphylli, Folium Eucommiae, Folium Mori, Radix Codonopsis, Radix Puerariae, America thorn Coriander,
Common milfoil is that mixed raw material becomes, and is according to the mass fraction: Herb Gynostemmae Pentaphylli 30~70%, Folium Eucommiae
10~50%, Folium Mori 4~20%, Radix Codonopsis 2~10%, Radix Puerariae 2~10%, America thorn Coriander
1~5%, common milfoil 1~5%.
Antihypertensive health care pharmaceutical composition containing Herb Gynostemmae Pentaphylli the most according to claim 1, it is special
Levying and be, described health medicine compositions is made up as with mass fraction of following raw material: strand
Blue 40~60%, Folium Eucommiae 20~40%, Folium Mori 6~15%, Radix Codonopsis 2~6%, Radix Puerariae
2~6%, America thorn Coriander 1~4%, common milfoil 1~4%.
Antihypertensive health care pharmaceutical composition containing Herb Gynostemmae Pentaphylli the most according to claim 2, it is special
Levying and be, in described health medicine compositions, each raw material is according to the mass fraction: Herb Gynostemmae Pentaphylli 50%,
Folium Eucommiae 30%, Folium Mori 10%, Radix Codonopsis 3%, Radix Puerariae 3%, America thorn Coriander 2%,
Common milfoil 2%.
4. according to the antihypertensive health care medicine group containing Herb Gynostemmae Pentaphylli according to any one of claims 1 to 3
Compound, it is characterised in that described Herb Gynostemmae Pentaphylli is diploid Herb Gynostemmae Pentaphylli blade and tetraploid Herb Gynostemmae Pentaphylli
Blade mixes.
Antihypertensive health care pharmaceutical composition containing Herb Gynostemmae Pentaphylli the most according to claim 4, it is special
Levy and be, the most described diploid Herb Gynostemmae Pentaphylli blade: tetraploid Herb Gynostemmae Pentaphylli blade=2:
5~5:2.
Antihypertensive health care pharmaceutical composition containing Herb Gynostemmae Pentaphylli the most according to claim 5, it is special
Levy and be, the most described diploid Herb Gynostemmae Pentaphylli blade: tetraploid Herb Gynostemmae Pentaphylli blade=1:
1。
7. according to the antihypertensive health care medicine group containing Herb Gynostemmae Pentaphylli according to any one of claims 1 to 3
Compound, it is characterised in that described health medicine compositions make tablet, pill, electuary,
Granule.
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CN107136506A (en) * | 2017-05-16 | 2017-09-08 | 陕西思尔生物科技有限公司 | A kind of Black Box Tracing piece with blood pressure reduction effect and preparation method thereof |
WO2017148183A1 (en) * | 2016-02-29 | 2017-09-08 | 谢其润 | Compound traditional chinese medicine composition containing gynostemma pentaphyllum and preparation method thereof |
CN108617821A (en) * | 2017-03-22 | 2018-10-09 | 平利县绞股蓝研究所 | A kind of anti-3-high health care tea beverage and preparation method thereof containing gynostemma pentaphylla |
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CN108617821A (en) * | 2017-03-22 | 2018-10-09 | 平利县绞股蓝研究所 | A kind of anti-3-high health care tea beverage and preparation method thereof containing gynostemma pentaphylla |
CN107136506A (en) * | 2017-05-16 | 2017-09-08 | 陕西思尔生物科技有限公司 | A kind of Black Box Tracing piece with blood pressure reduction effect and preparation method thereof |
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